Fraunhofer-Institut für Zelltherapie und Immunologie IZI

Publikationsliste

Publikationen 2025

Ahn D D, The N T, Song L H, Müller A, Velavan T P, Seliger B. Elevated soluble HLA-G levels associate with dengue severity in Vietnamese patients. J Med Virol. 2025, 97 (9):e70594. doi: 10.1002/jmv.70594
Ammar D, Sanges C, Henderson D, Schapitz I, Hudecek M, Luu M, Schüssler-Lenz M, Buchholz C, Franz P, Reiche K, Köhl U, Ifrah N, Quesnel B, Thermeli M, Kersten M J, Locatelli F, D'Amore M L, Bonini C, Casucci M, Philippar U, Doeswijk R, Thielen F, Uyl-de Groot C, Theelen J, Schröder B, Kremer A, Quaranta M, Prosper F, Brulle J van den, Grawunder U, Donnadieu E, Galy A, Ferrand C, Worel N, Busch D, Briones J, Sellner L, Kuball J, Sureda A, Awigena-Cook J. Call for preserving specialized knowledge and contributions of the CAT to advancing ATMPs in Europe. Cytotherapy. 2026, 28 (1):101984. doi: 10.1016/j.jcyt.2025.09.007. Epub 2025 Sep 23
Andersen J L, Banke S, Fagerberg R, Flamm C, Merkle D, Stadler P F. Pathway realizability in chemical networks. J Comput Biol. 2025, 32 (2): 164-187. doi: 10.1089/cmb.2024.0521
Arend L, Adamowicz K, Schmidt J R, Burankova Y, Zolotareva O, Tsoy O, Pauling J K, Kalkhof S, Baumbach J, List M, Laske T. Systematic evaluation of normalization approaches in tandem mass tag and label-free protein quantification data using PRONE. Brief Bioinform. 2025, 26 (3): bbaf201. doi: 10.1093/bib/bbaf201
Bauer M, Santos P, Wilfer A, Berg E van den, Zietsman A, Vetter M, Kaufhold S, Wickenhauser C, Dos-Santos-Silva I, Chen W C, Cubasch H, Murugan N, McCormack V, Joffe M, Seliger B, Kantelhardt E. HIV status alters immune cell infiltration and activation profile in women with breast cancer. Nat Commun. 2025, 16 (1): 4699. doi: 10.1038/s41467-025-59408-8
Bloße A, Pirlich M, Dietz A, Möser C, Arnold K, Freitag J, Neumuth T, Smith D M, Kubitschke H, Gaenzle M. Fluorescence-guided surgery in head and neck Squamous cell carcinoma (HNSCC). Int. J. Transl. Med. 2025, 5 (3), 40. doi: 10.3390/ijtm5030040
Blum A, Xiang W, Wien F, Thureau A, Chevreuil M, Raynal B, Geissler S, Wermann M, Schilling S, Bénas P, Hartlage-Rübsamen M, Schulze A, Sauter C, Roßner S. Monomers, dimers, and oligomers of pyroglutamate-modified α-Synuclein fragments exhibit distinct biophysical characteristics. ACS Chem Neurosci. 2025, 16 (10): 1919-1936. doi: 10.1021/acschemneuro.5c00106
Born P, Fandrei D, Wang S Y, Perez-Fernandez C, Fischer L, Ussmann J, Bach E, Hoffmann S, Metzeler K H, Herling M, Herling C, Jentzsch M, Boldt A, Seiffert S, Baber R, Weidner H, Franke G-N, Denecke T, Sabri O, Platzbecker U, Vucinic V, Meyer H J, Kurch L, Merz M. Prognostic significance of PET/CT for CAR T cell therapy in relapsed/refractory multiple myeloma. Hemasphere. 2025, 9 (6): e70159. doi: 10.1002/hem3.70159
Braun T, Kuschel F, Reiche K, Merz M, Herling M. Emerging T-cell lymphomas after CAR T-cell therapy. Leukemia. 2025, 9 (6): 1337-1341. doi: 10.1038/s41375-025-02574-x
Braun T, Rade M, Merz M, Klepzig H, Große F, Fandrei D, Pham N-N, Kreuz M, Kuhn C K, Kuschel F, Löffler D, Meinel J, Heger E, Schweinsberg V, Pflug N, Platzbecker U, Hallek M, Holtick U, Köhl U, Scheid C, Reiche K, Herling M, Richardson T. Multiomic profiling of T cell lymphoma after therapy with anti-BCMA CAR T cells and GPRC5D-directed bispecific antibody. Nat Med. 2025, 31 (4): 1145-1153. doi: 10.1038/s41591-025-03499-9
Burankova Y, Abele M, Bakhtiari M, Toerne C von, Barth T K, Schweizer L, Giesbertz P, Schmidt J R, Kalkhof S, Müller-Deile J, Veelen P A van, Mohammed Y, Hammer E, Arend L, Adamowicz K, Laske T, Hartebrodt A, Frisch T, Meng C, Matschinske J, Späth J, Röttger R, Schwämmle V, Hauck S M, Lichtenthaler S F, Imhof A, Mann M, Ludwig C, Kuster B, Baumbach J, Zolotareva O. Privacy-preserving multicenter differential protein abundance analysis with FedProt. Nat Comput Sci. 2025, 5 (8): 675-688. doi: 10.1038/s43588-025-00832-7
Cavina L, Alocén Portillo A, Balmer M P A, Dammer J C, Schillemans D, Hamdani S H, Ackerschott B, Dieteren C E J, Martina B E E, Buuren B N M van, Rockstroh A, Ulbert S, Hermkens P H H, Llinàs Brunet M, Gironés D, Feiters M, Rutjes F P J T. Development of lipopeptides as orthoflavivirin inhibitors with low micromolar broad-spectrum antiorthoflaviviral activity. J Med Chem. 2025, 68 (21): 22386-22400. doi: 10.1021/acs.jmedchem.5c01364
Ciok M, Diener J, Otte F, Feimer J, Nichterlein M, Kalkhof S, Noll M. Biocide-containing facades alter culture-based bacterial and fungal community composition and resistance patterns to octylisothiazolinone. Microorganisms. 2025, 13 (10): 2284. doi: 10.3390/microorganisms13102284
Coşkuner Leineweber Ö, Pothineni B K, Schumann N, Hofmann U, Möser C, Smith D M, Grundmeier G, Zhang Y, Keller A. Vancomycin-modiﬁed DNA origami nanostructures for targeting bacterial pathogens. Small Structures 2025, 6 (12): e202500246. doi: 10.1002/sstr.202500246
Couto P S, Stibbs D J, Springuel P, Schultz U, Effenberger M, Goldrick S, Navarro-Velázquez S, Juan M, Herbst L, Nießing B, Mestermann K, Sanges C, Hudecek M, Rafiq Q A. Impact of serum/xeno-free medium and cytokine supplementation on CAR-T cell therapy manufacturing in stirred tank bioreactors. Biotechnol J. 2025, 20 (9): e70114. doi: 10.1002/biot.70114
De Angelis B, D'Amore M L, Lecot P, Neininger K, Lorrain M, Gambotti L, Dreuillet C, Courcault E, Chatterjee S, Delgado J, Galy A, Franz P, Rodriguez-Madoz J R, Cabrerizo Y, Richter A, Girvalaki C, Noviello M, Tassi E, Sanges C, Luu M, Hudecek M, Kremer A, Locatelli F, Negre H, Quintarelli C. European survey on CAR T-Cell analytical methods from apheresis to post-infusion immunomonitoring. Front Immunol. 2025, 16: 1567582. doi: 10.3389/fimmu.2025.1567582
Di Giacomo A M, Subudhi S, Vos W, Andreatta M, Carmona S, McTavish W, Seliger B, Ibrahim R, Lahn M, Smith M, Eggermont A, Fox B A, Maio M. Perspectives on the role of “-Omics” in predicting response to immunotherapy. Eur J Cancer. 2025, 220: 115393. doi: 10.1016/j.ejca.2025.115393
Eick S, Taudte N, Ramsbeck D, Magdon A, Sculean A, Potempa J, Buchholz M. Effect of a bacterial glutaminyl cyclase inhibitor on multi-species-biofilms. Front. Oral Health, 01 December 2025, Sec. Oral Infections and Microbes, Volume 6 - 2025. doi: 10.3389/froh.2025.1716625
Fanti Z, Braumann U-D, Rauscher F G, Ebert T, Bribiesca E, Martinez-Perez M E. Slope chain code-based scale-independent tortuosity measurement on retinal vessels. Exp Eye Res. 2025, 254: 110286. doi: 10.1016/j.exer.2025.110286
Ferle M, Grieb N, Kreuz M, Ader J, Goldschmidt H, Mai E K, Bertsch U, Platzbecker U, Neumuth T, Reiche K, Oeser A, Merz M. Predicting progression events in multiple myeloma from routine blood work. NPJ Digit Med. 2025, 8 (1): 231. doi: 10.1038/s41746-025-01636-9
Fertey J, Makert G R, Becker P, Finkensieper J, Ulbert S. Low-energy electron irradiation inactivates viruses in serum and maintains growth-promoting properties in cell culture. Appl Biosaf. 2025, 30 (3): 264-271. doi: 10.1089/apb.2024.0031
Filippi Xavier L, Gacesa R, Oliveira Da Rocha G H, Broering M F, Scharf P, Silva Lima F da, Faber K N, Harmsen H, Hoffmann C, Poliselli Farsky S H. Annexin A1 levels affect microbiota in health and DSS-induced colitis/inflammatory bowel disease development. Front. Immunol 2025, 16: 1679071. doi: 10.3389/fimmu.2025.1679071
Friedrich VD, Neier K, Müller K, Fogal B, Loncova Z, Rade M, Shoaib M, Köhl U, Hoyt K, Pande P, Blanchard L, Raymond E, Scholz M, Reiche K, Kirsten H. Deep learning-aided inter-species-comparison reveals shared and distinct molecular patterns in cynomolgus monkey and humans following non-specific T cell activation. Front Immunol. 2025, 16: 1603716. doi: 10.3389/fimmu.2025.1603716
Gogesch P, Iannazzo S O, Rupp N, Rom J, Kreuz M, Reiche K, Anzaghe M, Waibler Z, on behalf the imSAVAR Consortium. Immune cells play a critical role in cytokine- and endotoxin-mediated endothelial permeability. PLoS One. 2025, 20 (8): e0329700. doi: 10.1371/journal.pone.0329700
Haupt J, Keminer O, Neser C, Windshügel B, Wiltzsch V, Schmidt J, Pliushcheuskaya P, Künze G, Scholz U, Müller C, Oliveira da Rocha G H, Biermann M, Zdzieblo D, Metzger M, Schiefke I, Neurath M, Siegmund B, Claussen C, Köhl U, Geisslinger G, Buchholz M, Kalkhof S, Lehmann J. Novel aryl hydrocarbon receptor agonists as potential anti-inflammatory therapeutics: Identification and validation through drug repurposing. Biochem Pharmacol. 2025, 240: 117066. doi: 10.1016/j.bcp.2025.117066
Horbas H, Bauer M, Eckert A, Bethmann D, Wilfer A, Seliger B, Wickenhauser C. Comparison of manual versus QuPath software-based immunohistochemical scoring using oral squamous cell carcinoma as a model. J Histochem Cytochem. 2025, 73 (5-6): 181-196. doi: 10.1369/00221554251335698
Jaeckel E, Friedman S L, Hudecek M, Protzer U. Chimeric antigen receptor (CAR) T-cell therapy: engineering immune cells to treat liver diseases. Review J Hepatol. 2025, 83 (5): 1156-1171. doi: 10.1016/j.jhep.2025.06.007
Keitel V, Kreissl MC, Goetze T, Dröge C, Kuhn CK, Pham NN, Löffler D, Borie D, Schreiber J, Boettcher M, Hippe K, Pech M, Mikusko M, Köhl U, Walther D, Reiche K, Mougiakakos D. CAR T-cell therapy induces remission in multiorgan IgG4-related disease with hepatobiliary involvement. J Hepatol. 2025 Dec 8:S0168-8278(25)02711-4. doi: 10.1016/j.jhep.2025.11.027
Kiefer N, Klein J, Beyer F, Burghardt B, Rohr M, Klein M, Burghardt M, Noll M, Kalkhof S. Experimental and computational identification of essential parameters governing biocide distribution in soil. Environ Toxicol Chem. 2025, 44 (10): 3037-3050. doi: 10.1093/etojnl/vgaf156
Kiefer N, Klein J, Rohr M, Noll M, Burkhart M, Klein M, Kalkhof S. Simulation of the biocide distribution in soil using PELMO coupled with COMLEAM. Environ Sci Pollut Res Int. 2025, 32 (5): 2425-2440. doi: 10.1007/s11356-024-35760-y
Kirchhoff H, Schoenherr C, Fleischer L, Schweighart E K, Esser R, Talbot S R, Schambach A, Köhl U, Heidenreich O, Eder M, Scherr M. Combination of targeted pharmacotherapy and immunotherapy with anti-CD19 CAR NK cells in acute lymphoblastic leukemia. Hemasphere. 2025, 9 (10): e70238. doi: 10.1002/hem3.70238
Kitte R, Serfling R, Blache U, Seitz C, Schrader S, Köhl U, Fricke S, Bär C, Tretbar S U. Optimal chimeric antigen receptor (CAR)-mRNA for transient CAR T cell generation. Int J Mol Sci. 2025, 26 (3): 965. doi: 10.3390/ijms26030965
Körtge A, Kamper C, Klinkmann G, Wasserkort R, Mitzner S. In vitro assessment of drug adsorption profiles during hemoadsorption therapy. Blood Purif. 2025, 54 (4-5): 218-225. doi: 10.1159/000545120
Krames W E A, Dayi D I, Kaiser L, Riester O, Himmelhaus M, Csuk R, Deigner H-P. WGM sensors for future diagnostics: small molecules to whole organisms. Biosens. Bioelectron. (UK). 2025, 26: 100671. doi: 10.1016/j.biosx.2025.100671
Kurz K S, Steinlein S, Kreuz M, Ziepert M, Staiger A M, Barth T F E, Möller P, Bernd H-W, Feller A C, Richter J, Klapper W, Stein H, Hartmann S, Hansmann M-L, Trümper L, Loeffler M, Schmitz N, Rosenwald A, Ott G, Horn H, DSHNHL/GLA. Age- and gender-specific molecular characteristics of diffuse large B-cell lymphoma: results from clinical trials of the DSHNHL/GLA. Hemasphere. 2025, 9 (3): e70093. doi: 10.1002/hem3.70093
Lehmann S, Lange U G, Oberbach A, Retschlag U, Morgenroth R, Busse H, Prettin C, Petroff D, Seidemann L, Blüher M, Dietrich A. The effect of 6 months of structured strength or endurance exercise program on weight loss after gastric bypass surgery in a randomized controlled trial. Langenbecks Arch Surg. 2025, ;410 (1): 194. doi: 10.1007/s00423-025-03731-7
Marton C, Clémenceau B, Dachy G, Demerle C, Derenne S, Ferrand C, Giverne C, Latouche J-B, Lemée L, Martinet J, Bonig H, Bensoussan D, Chabannon C, Köhl U, Deschamps M, Vos J de, Diana J, Dougé A, Forcade E, Galaine J, Thiant S, Galy A, Larghero J, Reppel L, Viel S, Boyer O, Yakoub-Agha I. Harmonisation of quality control tests for academic production of CAR-T cells: a position paper from the WP-bioproduction of the UNITC consortium. Bone Marrow Transplant. 2025, 60 (9): 1209-1217. doi: 10.1038/s41409-025-02637-8
Mazein A, Lopata O, Reiche K, Sewald K, Alb M, Sakellariou C, Gogesch P, Morgan H, Neuhaus V, Pham N-N, Sommer C, Perkins E, Fogal B, Shoaib M, Schneider R, Satagopam V, Ostaszewski M. An explorable model of an adverse outcome pathway of cytokine release syndrome related to the administration of immunomodulatory biotherapeutics and cellular therapies. Front Immunol. 2025, 16: 1601670. doi: 10.3389/fimmu.2025.1601670
Nelz S-C, Lück E, Schölzel A, Sauer M, Heskamp J, Doss S. Ex vivo plasma application on human brain microvascular endothelial-like cells for blood-brain barrier modeling. Int J Mol Sci. 2025, 26 (7): 3334. doi: 10.3390/ijms26073334
Nguven T T, Ho P, Staudt S, Gregoire C, Ziegler-Martin K, Jassin M, Block A, Hudecek M, Melenhorst J, Caers J, Luu M. Fine tuning towards the next generation of engineered T cells. Nat Biomed Eng. 2025, 9 (10): 1610-1631. doi: 10.1038/s41551-025-01492-8
Nichterlein M, Kiefer N, Hohner J, Stapf D, Schatz M, Noll M, Kalkhof S. Encapsulated biocides in facade materials impact leaching and UV stability, resulting in lower aquatic toxicity of the eluates. Environ Sci Pollut Res Int. 2025, 32 (27): 16324-16339. doi: 10.1007/s11356-025-36647-2
Peña‑Rodríguez A, Ramírez‑Sánchez I, Leptihn S, Quiroz‑Guzmán E. A novel vibriophage vB_Vp_PvVp04 against pathogenic Vibrio parahaemolyticus and its formulation for inclusion in shrimp feed. Aquaculture Int. 2025, 33: 117. doi: 10.1007/s10499-024-01797-6
Pennings E R, Spanjaart A M, Thielen F W, Oerlemans S, Fleischer A, Sanges C, Gomes Da Silva M, Cabrerizo Y, Lecot P, Roux-Opstaele L, Dreuillet C, Gonzalez-Marcano E, Millán O, Jaeger U, Delgado J, Luu M, Huber B, Lorrain M, Galhardas Pina M, Kremer A, Bolanos N, Clavreul S, Nier S, Liu R D K, Lissenberg-Witte B I, Anguille S, Robin M, Morris E C, Sureda A, Préau M, Pannard M, Bock G H de, Wagers S S, Trebeden-Negre H, Maucort-Boulch D, Hudecek M, Uyl-de Groot C A, Kersten M. Patient-reported outcomes in patients with hematologic malignancies treated with CAR T-cell therapy in Europe. Blood Adv. 2025, 9 (24): 6380-6393. doi: 10.1182/bloodadvances.2025017081
Petri K, D'Ippolito E, Künkele A, Köhl U, Busch D H, Einsele H, Hudecek M. Next-generation T cell immunotherapies engineered with CRISPR base and prime editing: challenges and opportunities. Nat Rev Clin Oncol. 2025, 22 (12): 902-923. doi: 10.1038/s41571-025-01072-4
Petroni G, Galassi C, Gouin K H, Chen H-H, Buqué A, Bloy N, Yamazaki T, Sato A, Beltrán-Visiedo M, Campia G, Jiménez-Cortegana C, Shah A, Kirchmair A, Massa C, Wickenhauser C, de Andrea C E, Navarro-Rubio B, Serrano-Mendioroz I, Navarro Manzano E, Satty A M, Rippon B, Finotello F, Trajanoski Z, Zhou X K, Scandura J M, García-Martínez E, Ayala de la Peña F, Rodríguez-Ruiz M E, Seliger B, Sánchez-Margalet V, de la Cruz-Merino L, Basho R K, Shiao S L, McArthur H L, Formenti S C, Knott S R V, Galluzzi L. IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR+HER2- breast cancer via CX3CR1+ macrophages. Nat Cancer. 2025, 6 (10): 1656-1675. doi: 10.1038/s43018-025-01007-z
Popp G, Jöckel L, Kläs M, Wiener T, Hilger N, Stumpf N, Groß J, Dünkel A, Blache U, Fricke S, Franz P. A user-centric approach to reliable automated flow cytometry data analysis for biomedical applications. Cytometry A. 2025, 107 (2): 111-125. doi: 10.1002/cyto.a.24913
Rade M, Fandrei D, Kreuz M, Seiffert S, Grahnert A, Friedrich M, Wiemers T, Born P, Fischer L, Weidner H, Hofbauer LC, Baber R, Wang SY, Bach E, Hoffmann S, Scolnick J, Friedrich M, Keramati F, Brazda P, Sebestyen Z, Kuball J, Alb M, Scheller L, Hudecek M, Einsele H, Metzeler KH, Herling M, Herling CD, Jentzsch M, Franke GN, Boldt A, Köhl U, Platzbecker U, Vucinic V, Reiche K, Merz M. A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma. Cancer Cell. 2025, S1535-6108 (25) 00490-8. doi: 10.1016/j.ccell.2025.10.014
Reis T, Ramírez-Guerrero G, Pecoits-Filho R, Lorenzin A, Cal M de, Corradi V, Klinkmann G, Ronco F, Neves F A R, Bellomo R, Ronco C. Iodinated contrast adsorption in cartridges with styrene-divinylbenzene sorbent. Artif Organs. 2025, 49 (5): 813-819. doi: 10.1111/aor.14949
Reiß F, Kiefer N, Tanunchai B, Reiss P, Kalkhof S, Noll M. Continuous intake of facade eluates affects active and total soil Microbiome. Biol. Fertil. Soils. 2025, 62: 75-95. doi: 10.1007/s00374-025-01955-9
Renner A, Finkbeiner M S C, Haas F V, Stahringer A, Lindow M, Delaroque N, Szardenings M, Fricke S, Köhl U, Engeland C E, Schmiedel D. Enhanced solid tumor cell targeting by a neoepitope-encoding oncolytic measles virus combined with CAR therapy. Mol Ther Oncol. 2025, 33 (4): 201043. doi: 10.1016/j.omton.2025.201043
Riester Z, Surowka M, Seifert N, Darowski D, Ghosh A, Spieler P, Weber J, Gianotti R, Freitag F, Alb M, Nerreter T, Gerhard-Hartmann E, Rosenwald A, Sauer M, Moessner E, Einsele H, Ferrara-Koller C, Klein C, Hudecek M, Danhof S. Co-expression of an adapter CAR retains efficacy of CAR T cells after single and dual antigen loss in lymphoma. Mol Ther. 2025, S1525-0016(25)00867-6. doi: 10.1016/j.ymthe.2025.10.046
Ritter J, Falckenhayn C, Qi M, Gather L, Gutjahr D, Schmidt J, Simm S, Kalkhof S, Hildebrand J, Bosch T, Winnefeld M, Grönniger E, Siracusa A. Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system. Aging (Albany NY). 2025, 17 (7): 1784-1809. doi: 10.18632/aging.206288
Roßbach L, Eichenberg T, Pietzsch N, Franz P, Fricke S, Sieg R, Dünkel A, Adlkofer KS. "Live" cell shipment-a forward-looking transport option for cryo-sensitive cell-based therapies. Front Bioeng Biotechnol. 2025, 13: 1706927. doi: 10.3389/fbioe.2025.1706927
Salti H, Nelz S-C, Lichtwark S, Pohl C, Kramer L, Lorenz M, Lemcke H, Doss S, Mitzner S, Wasserkort R. Recellularization of Scaffolds derived from precision-cut kidney slices. Biomed Mater. 2025, 20 (6). doi: 10.1088/1748-605X/ae05a4
Sandetskaya N, Kölsch A, Mattern K, Vater V, Kuhlmeier D, Priller F. CampyTube: Seamless Integration of a Molecular Test and Lateral Flow Detection of Campylobacter in a Single Vial. Biosensors (Basel). 2025, 15 (8), 497. doi: 10.3390/bios15080497
Sattler T, Benka B, Zimpernik I, Pürrer S, Waldner K, Duscher G G, Kuffer-Rosewick A, Fertey J, Ulbert S, Schmoll F. Retrospective cross-sectional study of occupational infection risk with zoonotic pathogens in austrian veterinary practitioners in the year 2022. Vet Med Sci. 2025, 11 (5): e70485. doi: 10.1002/vms3.70485
Scheller L, Zhou X, Loeffler-Wirth H, Kreuz M, Kadel SK, Schimanski S, Schulze H, Ruckdeschel A, Eisele F, Konetzki V, Jornet Culubret M, Merz M, Mersi J, Waldschmidt J, Danhof S, Köhl U, Kortüm KM, Rasche L, Einsele H, Düll J, Topp MS, Hudecek M, Reiche K, Alb M. Endothelial dysfunction and proinflammatory state determine severe hematotoxicity and inferior outcome of CAR-T therapy. Hemasphere. 2025, 9 (12): e70267. doi: 10.1002/hem3.70267
Schindler-Wnek K, Stahringer A, Heimer N, Köhl U, Fricke S, Schmiedel D. Divergent on-target off-tumor effects by CAR T and CAR NK cells suggest different efficacy and safety of cell therapies. Oncoimmunology. 2025, 14 (1): 2546443. doi: 10.1080/2162402X.2025.2546443
Schmidt J, Sopel N, Rist C, Ohs A, Dawid L, Simm S, Catanese L, Rupprecht H, Jobst-Schwan T, Lehmann J, Daniel C, Kalkhof S, Schiffer M, Müller-Deile J. Dysregulated protease homeostasis defines primary focal segmental glomerulosclerosis. Kidney360. 2025. ahead of print. doi: 10.34067/KID.0000001021
Schwarzer A, Ziegler U, Fertey J, Kreuz M, Vahlenkamp T W, Groschup M H, Ulbert S. Serological differentiation of West Nile, Usutu, and tick-borne encephalitis virus antibodies in birds and horses using mutant E protein ELISAs. Sci Rep. 2025, 15 (1): 28752. doi: 10.1038/s41598-025-14448-4
Seiffert S, Blaudszun, A-R, Shibru B, Körfer J, Köhl U, Fricke S, Sack U, Boldt A. Differential expression of immune checkpoints TIM-3, LAG-3, TIGIT, and Siglec-7 on circulating natural killer cells - insights from healthy donors compared to gastric cancer patients. Oncol Res Treat. 2025, 48 (10): 585-600. doi: 10.1159/000545429
Seiffert S, Kirchberg J, Bach E, Menger V, Brückner M, Sack U, Köhl U, Platzbecker U, Boldt A, Herling M, Vučinić V. Extracorporeal photopheresis - new insights into an old procedure. Transfus Med. 2025 Jun 10. doi: doi: 10.1111/tme.13156
Seliger B, Massa C. CyTOF as a suitable tool for stratification and monitoring of cancer patients. J Transl Med. 2025, 23 (1): 724. doi: 10.1186/s12967-025-06764-0
Selpiev Z, Leptihn S, Müsken M, Loh B. Deciphering shared receptor usage in genomically unrelated bacteriophages infecting hypervirulent Klebsiella pneumoniae K1 ST23. FEMS Microbes. 2025, 6: xtaf014. doi: 10.1093/femsmc/xtaf014
Song Y, Lee S, Heo S-W, Spohn J, Schmiedel D, Heo T, Kim S, Park J, Seo H R. HO-1197 as a multifaceted therapeutic: targeting the cell cycle, angiogenesis, metastasis, and tumor immunity in hepatocellular carcinoma. Int J Mol Sci. 2025, 26 (21): 10329. doi: 10.3390/ijms262110329
Stubenvoll A, Schmidt M, Moeller J, Lingner Chango M A, Schultz C, Antoniadou O, Loeffler-Wirth H, Bernhart S, Große F, Thier B, Paschen A, Anderegg U, Simon J C, Ziemer M, Schoeder C T, Binder H, Kunz M. Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity. Cancer Commun (Lond). 2025, 45 (4): 465-470. doi: 10.1002/cac2.12651
Subbarayan K, Bieber H, Massa C, Rodríguez F A E, Hossain S M AA, Neuder L, Wahbi W, Salo T, Tretbar S, Al-Samadi A, Seliger B. Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers. J Transl Med. 2025, 23 (1): 294. doi: 10.1186/s12967-025-06177-z
Tony L T, Stabile A, Schauer M P, Hudecek M, Weber J. CAR-T cell therapy for solid tumors. Transfus Med Hemother. 2025, 52 (1): 96–108. doi: 10.1159/000542438
Udinotti M, Sieboldts U, Bauer M, Vaxevanis C, Asiminas A, Lorenz K, Dierks C, Wickenhauser C, Seliger B. Fibroblast activation protein (FAP)-mediated promotion of metastasis via the FN1-TGFβ axis and immune suppression in aggressive thyroid cancer. J Transl Med. 2025, 23 (1): 1284. doi: 10.1186/s12967-025-07307-3
Uhlmann L, Pierer M, Krasselt M, Franke G, Zeidler R, Sabri O, Denecke T, Sack U, Köhl U, Boldt A, Borie D, Wagner U, Platzbecker U, Vucinic V. Effective use of anti-CD19 chimeric antigen receptor T cells in a case of treatment-resistant granulomatosis with polyangiitis. Ann Rheum Dis. 2025, 84 (7): 1280-1283. doi: 10.1016/j.ard.2025.04.029
Weber J, Rade M, Michael J, Tony L T, Freitag F, Spieler P, Müller C, Kalogirou C, Mainz L, Lehmann J, Klopfleisch R, Rosenfeldt M T, Danhof S, Kortüm K M, Köhl U, Einsele H, Rader C, Reiche K, Nerreter T, Hudecek M. ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice. Cell Rep Med. 2025, 6 (10): 102400. doi: 10.1016/j.xcrm.2025.102400
Wegner V D, Feile A, Alb M, Hudecek M, Hewitt P, Mosig A S. Short-chain fatty acids modulate anti-ROR1 CAR T-cell function and exhaustion in an intestinal adenocarcinoma-on-chip model. Adv Healthc Mater. 2025 May;14(13):e2405003. Epub 2025 Apr 18. doi: 10.1002/adhm.202405003
Weirauch U, Kreuz M, Birkenbihl C, Alb M, Quaranta M, Calzone L, Orozco-Ruiz S, Binder S, Fischer L, Clavreul S, Maguri M, Ferle M, Rade M, Azarias G, Hydren J R, Jamarik J, Schwarz D, Sebestyen Z, Kuball J, Popp G, Antoine C, Knockaert M, Schoeder C T, Fandrei D, Sanges C, Radvilas V, Gagelmann N, Rückert M, Penack O, Fricke S, Schmidt A, Ward C, Steinbeisser C, Van Gyseghem J-M, Niarakis A, Garderet L, Hudecek M, Neumuth T, Platzbecker U, Köhl U, Demlova R, Kremer A, Franke S, Fröhlich H, Merz M, Reiche K, CERTAINTY Consortium. Design specifications for biomedical virtual twins in engineered adoptive cellular immunotherapies. NPJ Digit Med. 2025, 8 (1): 493. doi: 10.1038/s41746-025-01809-6
Wiemers T, Ferle M, Ader J, Sotikova V, Fandrei D, Grieb N, Fischer L, Born P, Weidner H, Wang S Y, Jentzsch M, Franke G-N, Herling C, Metzeler K, Herling M, Heyn S, Denecke T, Reiche K, Platzbecker U, Vucinic V, Neumuth T, Meyer H-J, Merz M. Prognostic implications of splenomegaly in BCMA-directed CAR T-Cell therapy for relapsed myeloma. Transplant Cell Ther. 2025, 31 (10): 789-803. doi: 10.1016/j.jtct.2025.07.003
Wiltzsch V, Schmidt J R, Adamowicz K, Lauterbach T, Lehmann J, Baumbach J, Laske T, Kalkhof S. Systematic comparison of bone proteome extraction methods to allow for integrated proteomics-metabolomics correlation. J Proteome Res. 2025, 24 (9): 4362-4376. doi: 10.1021/acs.jproteome.4c01060
Yanik S D, Jameel K J, Rohde S, Bürger P, Bülthoff E, Grunwald T, Kronsbein J, Koch A, Edwards M R, Tenbusch M, Knobloch J. Cytokine production of mononuclear leukocytes in response to respiratory syncytial virus is increased in COPD but suppressed in non-COPD tobacco smokers. Mol Med. 2025 Jun 12;31(1):237. doi: 10.1186/s10020-025-01277-4
Ye J L, Grieger K, Lu D, Brandenberger C, Juchem M, Jordan M, Oehlsen L, Zardo P, Werlein C, Hesse C, Sewald K, Tretbar S, Thum T, Chatterjee S, Bär C. Telomerase modRNA offers a novel RNA-based approachto treat human pulmonary fibrosis. Aging Cell. 2025, 24 (11): e70240. doi: 10.1111/acel.70240

Publikationen 2024

Alb M, Reiche K, Rade M, Sewald K, Loskill P, Cipriano M, Maulana TI, van der Meer AD, Weener HJ, Clerbaux LA, Fogal B, Patel N, Adkins K, Lund E, Perkins E, Cooper C, van den Brulle J, Morgan H, Rubic-Schneider T, Ling H, DiPetrillo K, Moggs J, Köhl U, Hudecek M. Novel strategies to assess cytokine release mediated by chimeric antigen receptor T cells based on the adverse outcome pathway concept. J Immunotoxicol. 2024, 21 (sup1): S13-S28. doi: 10.1080/1547691X.2024.2345158. Epub 2024 Dec 10.
Aldehoff A S, Türkowsky D, Lohmann P, Homsi M N, Rolle-Kampczyk U, Ueberham E, Lehmann J, Bergen M von, Jehmlich N, Haange S-B. Revealing novel protein interaction partners of glyphosate in Escherichia coli. Environ Int. 2025: 195, 109243. doi: 10.1016/j.envint.2024.109243. Epub 2024 Dec 25.
Aleksandrova K, Leise J, Priesner C, Aktas M, Apel M, Assenmacher M, Bürger I, Richter A, Altefrohne P, Schubert C, Holzinger A, Barden M, Bezler V, von Bergwelt-Baildon M, Borchmann P, Goudeva L, Glienke W, Arseniev L, Esser R, Abken H, Koehl U. Automated manufacturing and characterization of clinical grade autologous CD20 CAR T cells for the treatment of patients with stage III/IV melanoma. Front Immunol. 2024, 15: 1328368. doi: 10.3389/fimmu.2024.1328368. eCollection 2024.
Altattan B, Ullrich J, Mattig E, Poppe A, Martins R, Bier F. Direct TAMRA-dUTP labeling of M. tuberculosis genes using loop-mediated isothermal amplification (LAMP). Sci Rep. 2024, 14(1): 5611. doi: 10.1038/s41598-024-55289-x
Araujo AE, Bentler M, Garmendia XP, Kaleem A, Fabian C, Morgan M, Hacker UT, Büning H. Adeno-associated virus vectors - a target of cellular and humoral immunity - are expanding their reach toward hematopoietic stem cell modification and immunotherapies. Hum Gene Ther. 2024, 35 (17-18): 586-603. doi: 10.1089/hum.2024.114
Barden M, Elsenbroich P R, Haas V, Ertelt M, Pervan P, Velas L, Gergely B, Szöőr Á, Harrer D C, Bezler V, Holzinger A, Friis R U W, Vereb G, Schütz G J, Schoeder C T, Hombach A A, Abken H. Integrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function. J Immunother Cancer. 2024, 12 (12): e010208. doi: 10.1136/jitc-2024-010208
Bauer M, Jäkel N, Wilfer A, Haak A, Eszlinger M, Kelemen K, Haemmerle M, Al-Ali HK, Seliger B, Wickenhauser C. Prognostic impact of the bone marrow tumor microenvironment, HLA-I and HLA-Ib expression in MDS and CMML progression to sAML. Oncoimmunology. 2024, 13 (1): 2323212. doi: 10.1080/2162402X.2024.2323212. eCollection 2024.
Bauer M, Monecke A, Hackl H, Wilfer A, Jaekel N, Bläker H, Al-Ali HK, Seliger B, Wickenhauser C. Association of immune evasion in myeloid sarcomas with disease manifestation and patients' survival. Front Immunol. 2024, 15: 1396187. doi: 10.3389/fimmu.2024.1396187. eCollection 2024.
Bauer M, Schöbel C-M, Wickenhauser C, Seliger B, Jasinski-Bergner S. Deciphering the role of alternative splicing in neoplastic diseases for immune-oncological therapies. Front Immunol. 2024, 15: 1386993. doi: 10.3389/fimmu.2024.1386993. eCollection 2024.
Bauser M, Einsele H, Löffler J, Hudecek M, Seif M. Engineering chimeric antigen receptor-natural killer cells targeting fungal infections using the non-viral Sleeping Beauty transposon system. J Vis Exp. 2024, 212. doi: 10.3791/67424
Benedyk-Machaczka M, Mydel P, Mäder K, Kaminska M, Taudte N, Naumann M, Kleinschmidt M, Sarembe S, Kiesow A, Eick S, Buchholz M. Preclinical validation of MIN-T: a novel controlled-released formulation for the adjunctive local application of minocycline in periodontitis. Antibiotics (Basel). 2024, 13 (11): 1012. doi: 10.3390/antibiotics13111012
Beneke V, Grieger KM, Hartwig C, Müller J, Sohn K, Blaudszun A-R, Hilger N, Schaudien D, Fricke S, Braun A, Sewald K, Hesse C. Homeostatic T helper 17 cell responses triggered by complex microbiota are maintained in ex vivo intestinal tissue slices. Eur J Immunol. 2024, 8: e2350946. doi: 10.1002/eji.202350946. Epub 2024 May 19.
Besecke J K, Kenner L, Poremba A, Schönfelder J, Teichmann T, Thoma M, Grunwald T, Hauff E von, König U, Poppe B, Schopf S. Method for the use of polymer beads as dosimeters for low-energy electron irradiation. Front. Phys. 2024, 12: 1490048. doi: 10.3389/fphy.2024.1490048
Bexte T, Botezatu L, Miskey C, Gierschek F, Moter A, Wendel P, Reindl LM, Campe J, Villena-Ossa JF, Gebel V, Stein K, Cathomen T, Cremer A, Wels WS, Hudecek M, Ivics Z, Ullrich E. Engineering of potent CAR NK cells using non-viral Sleeping Beauty transposition from minimalistic DNA vectors. Mol Ther. 2024, 32 (7): 2357-2372. doi: 10.1016/j.ymthe.2024.05.022. Epub 2024 May 14.
Blaess M, Csuk R, Schätzl T, Deigner H-P. Elongation of very long-chain fatty acids (ELOVL) in atopic dermatitis and the cutaneous adverse effect AGEP of drugs. Int J Mol Sci. 2024, 25 (17):9344. doi: 10.3390/ijms25179344
Buniatian GH, Schwinghammer U, Tremmel R, Cynis H, Weiss TS, Weiskirchen R, Lauschke VM, Youhanna S, Ramos I, Valcarcel M, Seferyan T, Rahfeld J-U, Rieckmann V, Klein K, Buadze M, Weber V, Kolak V, Gebhardt R, Friedman SL, Müller UC, Schwab M, Danielyan L. Consequences of amyloid-β deficiency for the liver. Adv Sci (Weinh). 2024, 11 (18): e2307734. doi: 10.1002/advs.202307734. Epub 2024 Mar 2.
Comoli P, Pentheroudakis G, Ruggeri A, Koehl U, Lordick F, Mooyaart JE, Hoogenbom JD, Urbano-Ispizua A, Peters S, Kuball J, Kröger N, Sureda A, Chabannon C, Haanen J, Pedrazzoli P. Current strategies of cell and gene therapy for solid tumors: results of the joint international ESMO and CTIWP-EBMT survey. Ann Oncol. 2024, 35 (4): 404-406. doi: 10.1016/j.annonc.2023.12.009
Derraz B, Breda G, Kämpf C, Baenke F, Cotte F, Reiche K, Köhl U, Kather JN, Eskenazy D, Gilbert S. New regulatory thinking is needed for AI-based personalised drug and cell therapies in precision oncology. NPJ Precis Oncol. 2024, ;8 (1): 23. doi: 10.1038/s41698-024-00517-w
Dinh-Le T, Escobar J, Poisson L, Adkins K, Jornet Culubret M, Scheller L, Brulle J van den, Hudecek M, Drake D R III, Alb M, Luna E. Identifying CD19-targeted CAR-T cell immune pathways in an in vitro human immune mimetic cytokine release assay. J Immunotoxicol. 2024, 21 (sup1): S29-S37. doi: 10.1080/1547691X.2024.2378729. Epub 2024 Dec 10.
Eberlein V, Rosencrantz S, Finkensieper J, Besecke JK, Mansuroglu Y, Kamp J-C, Lange F, Dressmann J, Schopf S, Hesse C, Thoma M, Fertey J, Ulbert S, Grunwald T. Mucosal immunization with a low-energy electron inactivated respiratory syncytial virus vaccine protects mice without Th2 immune bias. Front Immunol. 2024, 15: 1382318. doi: 10.3389/fimmu.2024.1382318. eCollection 2024.
Fandrei D, Seiffert S, Rade M, Rieprecht S, Gagelmann N, Born P, Wiemers T, Weidner H, Kreuz M, Schassberger T, Kossmann J, Mangold M, Furst D, Fischer L, Baber R, Heyn S, Wang SY, Bach E, Hoffmann S, Metzeler KH, Herlling M, Jentzsch M, Franke G-N, Köhl U, Friedrich M, Boldt A, Reiche K, Platzbecker U, Vucinic V, Merz M. Bispecific antibodies as bridging to BCMA CAR-T cell therapy for relapsed/refractory multiple myeloma. Blood Cancer Discov. 2025, 6 (1): 38-54. doi: 10.1158/2643-3230.BCD-24-0118. Epub 2024 Oct 23
Fischer L, Grieb N, Born P, Weiss R, Seiffert S, Boldt A, Fricke S, Franz P, Heyn S, Kubasch AS, Baber R, Weidner H, Wang SY, Bach E, Hoffmann S, Ussmann J, Kirchberg J, Hell S, Schwind S, Metzeler KH, Herling M, Jentzsch M, Franke G-N, Sack U, Reiche K, Köhl U, Platzbecker U, Vucinic V, Merz M. Cellular dynamics following CAR T cell therapy are associated with response and toxicity in relapsed/refractory myeloma. Leukemia. 2024, 38 (2): 372-382. doi: 10.1038/s41375-023-02129-y. Epub 2024 Jan 6.
Forni L, Aucella F, Bottari G, Büttner S, Cantaluppi V, Fries D, Kielstein J, Kindgen-Milles D, Krenn C, Kribben A, Meiser A, Mitzner S, Ostermann M, Premuzic V, Rolfes C, Scharf C, Schunk S, Molnar Z, Zarbock A. Hemoadsorption therapy for myoglobin removal in rhabdomyolysis: consensus of the hemoadsorption in rhabdomyolysis task force. BMC Nephrol. 2024, 25 (1): 247. doi: 10.1186/s12882-024-03679-8
Frielitz-Wagner I V, Mattutat J, Frielitz F S, Scheuermann K, Gesing J, Marheineke D, Löffler D, Kiess W, Körner A. Diurnal rythm of Nampt is gender and weight dependent. Obes Res Clin Pract. 2024, 18 (3): 181-188. doi: 10.1016/j.orcp.2024.06.005. Epub 2024 Jul 3.
Funcke S, Schmidt G, Bergholz A, Argente Navarro P, Azparren Cabezón G, Barbero-Espinosa S, Diaz-Cambronero O, Edinger F, García-Gregorio N, Habicher M, Klinkmann G, Koch C, Kröker A, Mencke T, Moral García V, Zitzmann A, Lezius S, Pepić A, Sessler DI, Sander M, Haas SA, Reuter DA, Saugel B. Cardiac index-guided therapy to maintain optimised postinduction cardiac index in high-risk patients having major open abdominal surgery: the multicentre randomised iPEGASUS trial. Br J Anaesth. 2024, 133 (2): 277-287. doi: 10.1016/j.bja.2024.03.040. Epub 2024 May 26.
Funk C, Uhlig N, Ruzsics Z, Baur F, Peindl M, Nietzer S, Epting K, Vacun G, Dandekar G, Botteron C, Werno C, Grunwald T, Bailer SM. TheraVision: engineering platform technology for the development of oncolytic viruses based on herpes simplex virus type 1. Mol Ther Oncol. 2024, 32 (1): 200784. doi: 10.1016/j.omton.2024.200784. eCollection 2024 Mar 21.
Gege C, Hahn F, Wangen C, Häge S, Herrmann A, Uhlig N, Eberlein V, Issmail L, Klopfleisch R, Grunwald T, Marschall M, Kohlhof H, Vitt D. Synthesis and characterization of DHODH inhibitors based on the vidofludimus scaffold with pronounced anti-SARS-CoV-2 activity. ChemMedChem. 2024, 19 (19): e202400292. doi: 10.1002/cmdc.202400292. Epub 2024 Aug 6.
Gehrke L, Gonçalves V D R, Andrae D, Rasko T, Ho P, Einsele H, Hudecek M, Friedel S R. Current non-viral-based strategies to manufacture CAR-T cells. Int J Mol Sci. 2024, 25 (24): 13685. doi: 10.3390/ijms252413685
Ghazizadeh E, Naseri Z, Deigner H-P, Rahimi H, Altintas Z. Approaches of wearable and implantable biosensor towards of developing in precision medicine. Front Med (Lausanne). 2024, 11: 1390634. doi: 10.3389/fmed.2024.1390634. eCollection 2024.
Gierschek F, Schlueter J, Kühnel I, Feigl FF, Schmiedel D, Prüfer M, Buchinger L, Cerwenka A, Cappel C, Huenecke S, Köhl U, Wels WS, Ullrich E. Empowering natural killer cells to combat acute myeloid leukemia: perspective on CAR-NK cell therapy. Transfus Med Hemother. 2024, 52 (1): 42-60. doi: 10.1159/000540962. eCollection 2025 Feb.
Gnoth K, Bär JW, Rosche F, Rahfeld J-U, Demuth H-U. Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme. PLoS One. 2024, 19 (4): e0289239. doi: 10.1371/journal.pone.0289239. eCollection 2024.
Grahnert A, Seiffert S, Wenk K, Schmiedel D, Boldt A, Vucinic V, Merz M, Platzbecker U, Klemann C, Köhl U, Friedrich M. Evaluation of anti-CAR linker mAbs for CAR T monitoring after BiTEs/bsAbs and CAR T-cell pretreatment. Biomedicines. 2024, 12 (8): 1641. doi: 10.3390/biomedicines12081641
Haller K, Doss S, Sauer M. In vitro hepatotoxicity of routinely Used opioids and sedative drugs. Curr Issues Mol Biol. 2024, 46 (4): 3022-3038. doi: 10.3390/cimb46040189
Hassan L, Bedir A, Kraus FB, Ostheimer C, Vordermark D, Mikolajczyk R, Seliger B, Medenwald D. Correlation of increased soluble tumor necrosis factor receptor 1 with mortality and dependence on treatment in non-small-cell lung cancer patients: a longitudinal cohort study. Cancers (Basel). 2024, 16 (3): 525. doi: 10.3390/cancers16030525
Herrmann A, Gege C, Wangen C, Wagner S, Kögler M, Cordsmeier A, Irrgang P, Ip W-H, Weil T, Hunszinger V, Groß R, Heinen N, Pfaender S, Reuter S, Klopfleisch R, Uhlig N, Eberlein V, Issmail L, Grunwald T, Hietel B, Cynis H, Münch J, Sparrer K M J, Ensser A, Tenbusch M, Dobner T, Vitt D, Kohlhof H, Hahn F. Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activity. Antiviral Res. 2024, 231: 106008. doi: 10.1016/j.antiviral.2024.106008. Epub 2024 Sep 19.
Hinestrosa C A, Fuchs J, Denecke T, Storch C, Dreyer A, Kuthning A, Reinhardt M, Rio Bartulos C, Wiggermann P, Busse H, Moche M. In vivo revascularization and tissue effects of uterine artery embolization with starch microspheres in sheep. Clin Hemorheol Microcirc. 2024, 88 (s1): S69-S84. doi: 10.3233/CH-248106
Höfling C, Donkersloot P, Ulrich L, Burghardt S, Opitz M, Geissler S, Schilling S, Cynis H, Michalski D, Roßner S. Dipeptidyl peptidase 4 deficiency improves survival after focal cerebral ischemia in mice and ameliorates microglia activation and specific inflammatory markers. Neurobiol Dis. 2024, 201: 106671. doi: 10.1016/j.nbd.2024.106671. Epub 2024 Sep 16.
Höfling C, Ulrich L, Burghardt S, Donkersloot P, Opitz M, Geissler S, Schilling S, Cynis H, Michalski D, Roßner S. Focal cerebral ischemia induces expression of glutaminyl cyclase along with downstream molecular and cellular inflammatory responses. Cells. 2024, 13 (17):1412. doi: 10.3390/cells13171412
Jaber M, Schmidt J, Kalkhof S, Gerstenfeld L, Duda G N, Checa S. OMIBONE: Omics-driven computer model of bone regeneration for personalized treatment. Bone. 2025 Jan:190:117288. doi: 10.1016/j.bone.2024.117288. Epub 2024 Oct 18.
Jung-Fittkau J, Diebold J, Kruse A, Deigner H-P, Schmidt MS. Measurement of the reaction enthalpy of CO2 in aqueous solutions with thermographic and gravimetric methods. Sci Rep. 2024, 14 (1): 10373. doi: 10.1038/s41598-024-61242-9
Kern K, Santa-Ardharnpreecha S, Delaroque N, Dölle-Bierke S, Treudler R, Ehrentreich-Förster E, Rothkopf I, Worm M, Szardenings M. Heat treatment of hazelnut allergens monitored by polyclonal sera and epitope fingerprinting. Foods. 2024, 13 (23): 3932. doi: 10.3390/foods13233932
Klinkmann G, Doss F, Doss S, Schwarz A, Reichert S, Reuter DA, Selleng K, Thiele T, Mitzner S, Altrichter J. Purified granulocyte concentrates from buffy coats with extended storage time. Transfus Med Hemother. 2024, 51 (6): 383-392. doi: 10.1159/000537698. eCollection 2024 Dec.
Köppen J, Kleinschmidt M, Morawski M, Rahfeld J-U, Wermann M, Cynis H, Hegenbart U, Daniel C, Roßner S, Schilling S, Schulze A. Identification of isoaspartate-modified transthyretin as potential target for selective immunotherapy of transthyretin amyloidosis. Amyloid. 2024, 31 (3): 184-194. doi: 10.1080/13506129.2024.2358121. Epub 2024 May 27.
Körtge A, Breitrück A, Doß S, Hofrichter J, Nelz S-C, Krüsemann H, Wasserkort R, Fitzner B, Hecker M, Mitzner S, Zettl UW. The utility of miniaturized adsorbers in exploring the cellular and molecular effects of blood purification - a pilot study with a focus on immunoadsorption in multiple sclerosis. Int J Mol Sci. 2024, 25 (5): 2590. doi: 10.3390/ijms25052590
Krause JL, Engelmann B, Schaepe SS, Rolle-Kampczyk U, Jehmlich N, Chang H-D, Slanina U, Hoffmann M, Lehmann J, Zenclussen AC, Herberth G, Bergen Mv. DSS treatment does not affect murine colonic microbiota in absence of the host. Gut Microbes. 2024, 16 (1): 2297831. doi: 10.1080/19490976.2023.2297831. Epub 2024 Jan 2.
Lawlor A, Beyer K, Russell B, Steinbeisser C, Bjartell A, De Meulder B, Omar MI, Hulsen T, Butler J, N'Dow J, Gómez Rivas J, Gandaglia G, Nicoletti R, Sakalis V, Smith EJ, Maass M, Zong J, Fullwood L, Abbott T, Tafreshiha A, Papineni K, Snijder R, Horgan D, Seager S, Evans-Axelsson S, Ribal MJ, Roobol MJ, Van Hemelrijck M; PIONEER Consortium. PIONEER big data platform for prostate cancer: lessons for advancing future real-world evidence research. Nat Rev Urol. 2025, 22 (2): 116-124. doi: 10.1038/s41585-024-00925-4. Epub 2024 Sep 9.
Lehmann S, Retschlag U, Oberbach A. Visceral fat mass dynamics in a 2-year randomized STrength versus ENdurance training trial in people with obesity. Diabetes Obes Metab. 2024, 26 (9): 4087-4099. doi: 10.1111/dom.15767. Epub 2024 Jul 16.
Li H, Wilhelm M, Baumbach CM, Hacker MC, Szardenings M, Rischka K, König A, Schulz-Kornas E, Fuchs F, Simon JC, Lethaus B, Savkovic V. Laccase-treated polystyrene surfaces with caffeic acid, dopamine, and L-3,4-Dihydroxyphenylalanine substrates facilitate the proliferation of melanocytes and embryonal carcinoma cells NTERA-2. Int J Mol Sci. 2024, 25 (11): 5927. doi: 10.3390/ijms25115927
Li J, Hietel B, Brunk M G K, Reimers A, Willems C, Groth T, Cynis H, Adelung R, Schütt F, Sacher WD, Poon JKS. 3D-printed microstructured alginate scaffolds for neural tissue engineering. Trends Biotechnol. 2025, 43 (2): 447-461. doi: 10.1016/j.tibtech.2024.10.013. Epub 2024 Dec 10.
Lomelí-Ortega CO, Barajas-Sandoval D, Ramírez-Sánchez I, Martínez-Villalobos JM, Leptihn S, Quiroz-Guzmán E. Complete genome sequence of Vibrio diabolicus bacteriophage vB_Vc_SrVc2 and its efficacy as prophylactic phage therapy. Virology. 2025, 602: 110322. doi: 10.1016/j.virol.2024.110322. Epub 2024 Nov 28.
Manohar P, Loh B, Nachimuthu R, Leptihn S. Phage-antibiotic combinations to control Pseudomonas aeruginosa-Candida two-species biofilms. Sci Rep. 2024, 14 (1): 9354. doi: 10.1038/s41598-024-59444-2
Manohar P, Loh B, Turner D, Tamizhselvi, Mathankumar M, Elangovan N, Nachimutu R, Leptihn S. In vitro and in vivo evaluation of the biofilm-degrading Pseudomonas phage Motto, as a candidate for phage therapy. Front Microbiol. 2024, 15: 1344962. doi: 10.3389/fmicb.2024.1344962. eCollection 2024.
Matúš D, Post W B, Groß V E, Kuhn C K, Knierim A B, Kuhn C K, Fiedler F, Tietgen D B, Schön J L, Schöneberg T, Prömel S. The N terminus-only (trans) function of the Adhesion GPCR Latrophilin-1 controls multiple processes in reproduction of C. elegans. G3 (Bethesda). 2024, 14 (11): jkae206. doi: 10.1093/g3journal/jkae206
Maulana TI, Teufel C, Cipriano M, Roosz J, Lazarevski L, van den Hil FE, Scheller L, Orlova V, Koch A, Hudecek M, Alb M, Loskill P. Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells. Cell Stem Cell. 2024, 31 (7): 989-1002.e9. doi: 10.1016/j.stem.2024.04.018. Epub 2024 May 15.
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Publikationen 2023

Adamowicz K, Arend L, Maier A, Schmidt J R, Kuster B, Tsoy O, Zolotareva O, Baumbach J, Laske T. Proteomic meta-study harmonization, mechanotyping and drug repurposing candidate prediction with ProHarMeD. NPJ Syst Biol Appl 2023, 9(1): 49. doi: 10.1038/s41540-023-00311-7
Agarwal B, Cañizares RB, Saliba F, Ballester MP, Tomescu DR, Martin D, Stadlbauer V, Wright G, Sheikh M, Morgan C, Alzola C, Lavin P, Green D, Kumar R, Sacleux SC, Schilcher G, Koball S, Tudor A, Minten J, Domenech G, Aragones JJ, Oettl K, Paar M, Waterstradt K, Bode-Boger SM, Ibáñez-Samaniego L, Gander A, Ramos C, Chivu A, Stange J, Lamprecht G, Sanchez M, Mookerjee RP, Davenport A, Davies N, Pavesi M, Andreola F, Albillos A, Cordingley J, Schmidt H, Carbonell-Asins JA, Arroyo V, Fernandez J, Mitzner S, Jalan R. Randomized, controlled clinical trial of the DIALIVE liver dialysis device versus standard of care in patients with acute-on- chronic liver failure. J Hepatol. 2023, Jul;79(1): 79-92. doi: 10.1016/j.jhep.2023.03.013
Ammar D, Schapitz I, Luu M, Hudecek M, Meyer M, Taps T, Schröder B, Ivics Z, Sanges C, Franz P, Koehl U, Negre H, Johanna I, Awigena-Cook J. Accelerating development of engineered T cell therapies in the EU: current regulatory framework for studying multiple product versions and T2EVOLVE recommendations. Front Immunol. 2023, Nov, 14: 1280826. doi: 10.3389/fimmu.2023.1280826
Anders I M, Schimmelpfennig C, Wiedemann K, Löffler D, Kämpf C, Blumert C, Reiche K, Kunz M, Anderegg U, Simon J-C, Ziemer M. Atypical fibroxanthoma and pleomorphic dermal sarcoma – gene expression analysis compared with undifferentiated cutaneous squamous cell carcinoma. J Dtsch Dermatol Ges 2023, 21 (5): 482-491. doi: 10.1111/ddg.15006
Auw N von, Serfling R, Kitte R, Hilger N, Zhang C, Gebhardt C, Dünkel A, Franz P, Köhl U, Fricke S, Tretbar SU. Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality. Sci Rep 2023, 13 (1), article 18160. doi: 10.1038/s41598-023-45197-x
Bache M, Kadler F, Struck O, Medenwald D, Ostheimer C, Güttler A, Keßler J, Kappler M, Riemann A, Thews O, Seliger B, Vordermark D. Correlation between circulating miR-16, miR-29a, miR-144 and miR-150, and the radiotherapy response and survival of non-small-cell lung cancer patients. Int J Mol Sci 2023, 24 (16), article 12835. doi: 10.3390/ijms241612835
Barendrecht S, Schreurs A, Geißler S, Sabanov V, Ilse V, Rieckmann V, Eichentopf R, Künemund A, Hietel B, Wussow S, Hoffmann K, Körber-Ferl K, Pandey R, Carter G W, Demuth H-U, Holzer M, Roßner S, Schilling S, Preuss C, Balschun D, Cynis H. A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice. Alzheimers Res Ther 2023, 15 (1), article 16. doi: 10.1186/s13195-022-01144-y
Bentler M, Hardet R, Ertelt M, Rudolf D, Kaniowska D, Schneider A, Vondran F W R, Schoeder C T, Delphin M, Lucifora J, Ott M, Hacker U T, Adriouch S, Büning H. Modifying immune responses to adeno-associated virus vectors by capsid engineering. Mol Ther Methods Clin Dev 2023, 30: 576-592. doi: 10.1016/j.omtm.2023.08.015
Blache U, Tretbar S, Koehl U, Mougiakakos D, Fricke S. CAR T cells for treating autoimmune diseases. RMD open 2023, 9 (4): e002907. doi: 10.1136/rmdopen-2022-002907
Blaudszun A-R, Kim W J, Um W, Yoon H Y, Shim M K, Kim K. Adoptive transfer of photosensitizer-loaded cytotoxic T cells for combinational photodynamic therapy and cancer immuno-therapy. Pharmaceutics. 2023,15 (4): 1295. doi: 10.3390/pharmaceutics15041295
Böhm K, Schulze-Niemand E, Kähne T, Siddiqui E, Täger C, Ramsbeck D, Buchholz M, Naumann M. Synthesis and structure–activity relationships of USP48 deubiquitinylase inhibitors. Arch Pharm 2023, 356 (7), article: 2200661. doi: 10.1002/ardp.202200661
Broséus J, Hergalant S, Vogt J, Tausch E, Kreuz M, Mottok A, Schneider C, Dartigeas C, Roos-Weil D, Quinquenel A, Moulin C, Ott G, Blanchet O, Tomowiak C, Lazarian G, Rouyer P, Chteinberg E, Bernhart SH, Tournilhac O, Gauchotte G, Lomazzi S, Chapiro E, Nguyen-Khac F, Chery C, Davi F, Hunault M, Houlgatte R, Rosenwald A, Delmer A, Meyre D, Béné MC, Thieblemont C, Lichter P, Ammerpohl O, Guéant JL; ICGC MMML-Seq Consortium; Guièze R, Martin-Subero JI, Cymbalista F, Feugier P, Siebert R, Stilgenbauer S. Molecular characterization of Richter syndrome identifies de novo diffuse large B-cell lymphomas with poor prognosis. Nat Commun. 2023, 14 (1): 309. doi: 10.1038/s41467-022-34642-6
Caballero L R, Treudler R, Delaroque N, Simon J C, Kern K, Szardenings M. Peptide epitopes as biomarkers of soya sensitization in rBet v 1 immunotherapy of birch-related soya allergy. Clin Exp Allergy 2023, 53 (3): 316-326. doi: 10.1111/cea.14224
Chilingaryan G, Izmailyan R, Grigoryan R, Shavina A, Arabyan E, Khachatryan H, Abelyan N, Matevosyan M, Harutyunyan V, Manukyan G, Hietel B, Shtro A, Danilenko D, Zakaryan H. Advanced virtual screening enables the discovery of a host-targeting and broad-spectrum antiviral agent. Antiviral Res 2023, 217, article 105681. doi: 10.1016/j.antiviral.2023.105681
Ciulean I S, Fischer J, Quaiser A, Bach C, Abken H, Tretbar U S, Fricke S, Köhl U, Schmiedel D, Grunwald T. CD44v6 specific CAR-NK cells for targeted immunotherapy of head and neck squamous cell carcinoma. Front Immunol 2023, 14: 1290488. doi: 10.3389/fimmu.2023.1290488
Dzhambazov B, Batsalova T, Merky P, Lange F, Holmdahl R. NIH/3T3 fibroplasts selectively activate T cells specific for posttranslationally modified collagen type II. Int J Mol Sci 2023, 24 (13), article: 10811. doi: 10.3390/ijms241310811
Eberlein V, Ahrends M, Bayer L, Finkensieper J, Besecke J K, Mansuroglu Y, Standfest B, Lange F, Schopf S, Thoma M, Dressman J, Hesse C, Ulbert S, Grunwald T. Mucosal application of a low-energy electron inactivated respiratory syncytial virus vaccine shows protective efficacy in an animal model. Viruses 2023, 15 (9), article 1846. doi: 10.3390/v15091846
Engel C, Wirkner K, Zeynalova S, Baber R, Binder H, Ceglarek U, Enzenbach C, Fuchs M, Hagendorff A, Henger S, Hinz A, Rauscher FG, Reusche M, Riedel-Heller SG, Röhr S, Sacher J, Sander C, Schroeter ML, Tarnok A, Treudler R, Villringer A, Wachter R, Witte AV, Thiery J, Scholz M, Loeffler M; LIFE-Adult-Study working group. Cohort Profile: The LIFE-adult-study. Int J Epidemiol 2023, 52 (1): E66 - E791. doi: 10.1093/ije/dyac114
Feigl F F, Stahringer A, Peindl M, Dandekar G, Köhl U, Fricke S, Schmiedel D. Efficient redirection of NK cells by genetic modification with chemokine receptors CCR4 and CCR2B. Int J Mol Sci 2023, 24 (4), article 3129. doi: 10.3390/ijms24043129
Finkensieper J, Mayerle F, Rentería-Solís Z, Fertey J, Makert G R, Lange F, Besecke J, Schopf S, Poremba A, König U, Standfest B, Thoma M, Daugschies A, Ulbert S. Apicomplexan parasites are attenuated by low energy electron irradiation in an automated microfluidic system and protect against infection with Toxoplasma gondii. Parasitol Res, 2023, 122(8): 1819-1832. doi: 10.1007/s00436-023-07880-w
Freitag J S, Möser C, Belay R, Altattan B, Grasse N, Pothineni B K, Schnauß J, Smith D M. Integration of functional peptides into nucleic acid-based nanostructures. Nanoscale 2023, 15 (17): 7608-7624. doi: 10.1039/d2nr05429a
Glaser M, Mollenkopf P, Prascevic D, Ferraz C, Käs J A, Schnauß J, Smith D M. Systematic altering of semiflexible DNA-based polymer networks via tunable crosslinking. Nanoscale. 2023, 15 (16): 7374-7383. doi: 10.1039/d2nr05615a
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He J, Shi Q, Chen Z, Zhang W, Lan P, Xu Q, Hu H, Chen Q, Jianzhong F, Jiang Y, Loh B W-C, Lepthin S, Zou Q, Zhang J, Yu Y, Hua X. Opposite evolution of pathogenicity driven by in vivo wzc and wcaJ mutations in ST11-KL64 carbapenem-resistant Klebsiella pneumoniae. Drug Resist Updat. 2023, 66: 100891. doi: 10.1016/j.drup.2022.100891
Hilali N, Hangouët M, Bausells J, Kern K, Ramirez-Caballero L, Szardenings M, Polonschii Cristina, Mohammadi H, Amime A, Zine N, Errachid A. Fast impedimetric immunosensing of IgGs associated with peanut and hazelnut allergens. Biosens Bioelectron 2023, 242, article: 115612. doi: 10.1016/j.bios.2023.115612
Hoen L, Pfeffer D, Schmidt J R, Kraft J, Hildebrand J, Kalkhof S. Hydration status of geriatric patients is associated with changes in plasma proteome, especially in proteins involved in coagulation. Nutrients 2023, 15 (17), article 3789. doi: 10.3390/nu15173789
Issmail L, Ramsbeck D, Jäger C, Henning T, Kleinschmidt M, Buchholz M, Grunwald T. Identification and evaluation of a novel tribenzamide derivative as an inhibitor targeting the entry of the respiratory syncytial virus. Antiviral Res 2023, article 105547. doi: 10.1016/j.antiviral.2023.105547
Kern K, Delaroque N, Boysen A, Puder M, Wendt R, Kölsch A, Ehrentreich-Förster E, Staerk K, Andersen T E, Andersen K, Lund L, Szardenings M. Glycosylation of bacterial antigens changes epitope patterns. Front Immunol 2023, 14: 1258136. doi: 10.3389/fimmu.2023.1258136
Kiefer N, Nichterlein M, Reiß F, Runge M, Biermann U, Wieland T, Noll M, Kalkhof S. Eluates from façades at the beginning of their service time affect aquatic and sediment organisms. Sci Total Environ 2023, 906, article 167531. doi: 10.1016/j.scitotenv.2023.167531
Kitte R, Rabel M, Geczy R, Park S, Fricke S, Koehl U, Tretbar SU. Lipid nanoparticles outperform electroporation in mRNA-based CAR T cell engineering. Mol Ther Methods Clin Dev, 2023, 31: 101139. doi: 10.1016/j.omtm.2023.101139
Klinkmann G, Waterstradt K, Klammt S, Schnurr K, Schewe J-C, Wasserkort R, Mitzner S. Exploring albumin functionality assays: a pilot study on sepsis evaluation in intensive care medicine. Int J Mol Sci 2023, 24 (16), article 12551. doi: 10.3390/ijms241612551
Klinkmann G, Wild T, Heskamp B, Doss F, Doss S, Milej M, Thiele L-M, Goudeva L, Blasczyk R, Reuter D, Altrichter J, Mitzner S. Extracorporeal therapy of sepsis by purified granulocyte concentrates—ex vivo circulation model. Artifical Organs 2023, 47 (7): 1151-1162. doi: 10.1111/aor.14507
Lozada-Chávez I, Lozada-Chávez A N, Stadler P F, Prohaska S J. The genomes of complex multicellular organisms on Earth are characterized by high intron-richness. Revista mexicana de astronomía y astrofísica 2023, 55. doi: 10.22201/ia.14052059p.2023.55.14
Massa C, Seliger B. Combination of multiple omics techniques for a personalized therapy or treatment selection. Front Immunol 2023, 14, article 1258013. doi: 10.3389/fimmu.2023.1258013
Massa C, Wang Y, Marr N, Seliger B. Interferons and resistance mechanisms in tumors and pathogen-driven diseases - focus on the major histocompatibility complex (MHC) antigen processing pathway. Int J Mol Sci 2023, 24 (7), article 6736. doi: 10.3390/ijms24076736
Messer E K, Meyer A L, Klaeske K, Sieg F, Eifert S, Schmiedel D, Haunschild J, Jawad K, Saeed D, Hildebrandt L, Borger M A, Dieterlen M-T. The impact of obesity on T and NK cells after LVAD implantation. Obes Facts 2023, 16 (4): 364-373. doi: 10.1159/000530174
Mollenkopf P, Prascevic D, Bayerl T M, Käs J A, Schnauß J. Heavy water induces bundling in entangled actin networks. RSC Adv 2023, 13 (35): 24795-24800. doi: 10.1039/d3ra03917j
Mötzing M, Blüher M, Grunwald T, Hoffmann R. Immunological quantitation of the glycation site Lysine‐414 in serum albumin in human plasma samples by indirect ELISA using highly specific monoclonal antibodies. ChemBioChem 2023, online ahead of print, article e202300550. doi: 10.1002/cbic.202300550
Mytzka N, Arbaciauskaite S, Sandetskaya N, Mattern K, Kuhlmeier D. A fully integrated duplex RT‑LAMP device for the detection of viral infections. Biomed Microdevices 2023, 25 (4), article 36. doi: 10.1007/s10544-023-00676-w
Nowak J, Bentele M, Kutle I, Zimmermann K, Lühmann J K, Steinemann D, Kloess S, Köhl U, Roßberg W, Ahmed A, Schaudien D, Neubert L, Kamp J-C, Kuehnel M P, Warnecke A, Schambach A, Morgan M. CAR-NK cells targeting HER1 (EGFR) show efficient anti-tumor activity against head and neck squamous cell carcinoma (HNSCC). Cancers (Basel) 2023, 15 (12), article 3169. doi: 10.3390/cancers15123169
Quint I, Simantzik J, Kaiser L, Laufer S, Csuk R, Smith D, Kohl M, Deigner H-P. Ready-to-use nanopore platform for label-free small molecule quantification: ethanolamine as first example. Nanomedicine 2023, online aheas of print, article 102724. doi: 10.1016/j.nano.2023.102724
Rade M, Böhlen S, Neuhaus V, Löffler D, Blumert C, Merz M, Köhl U, Dehmel S, Sewald K, Reiche K. A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation. Genome Biol. 2023, 24(1): 287. doi: 10.1186/s13059-023-03120-7
Rauch-Wirth L, Renner A, Kaygisiz K, Zimmermann L, Rodríguez Alfonso AA, Schütz D, Wiese S, Ständker L, Weil T, Schmiedel D, Münch J. Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer. Front Immunol. 2023, 14:1270243. doi: 10.3389/fimmu.2023.1270243
Rentschler S, Borgolte M, Filbert A, Laufer S, Deigner H-P. Highly efficient β-lactamase assay applying poly-dimethylacrylamide-based surface functionalization with β-lactam antibiotics and β-lactamase inhibitors. Lab Chip 2023, 23 (24): 5120-5130. doi: 10.1039/d3lc00682d
Reus P, Guthmann H, Uhlig N, Agbaria M, Issmail L, Eberlein V, Nordling-David MM, Jbara-Agbaria D, Ciesek S, Bojkova D, Cinatl J, Burger-Kentischer A, Rupp S, Zaliani A, Grunwald T, Gribbon P, Kannt A, Golomb G. Drug repurposing for the treatment of COVID-19: Targeting nafamostat to the lungs by a liposomal delivery system. J Control Release 2023, 364: 654-671. doi: 10.1016/j.jconrel.2023.10.050
Salti H, Kramer L, Nelz S-C, Lorenz M, Breitrück A, Hofrichter J, Frank M, Schulz K, Mitzner S, Wasserkort R. Decellularization of precision-cut kidney slices-application of physical and chemical methods. Biomed Mater 2023, 18 (2), article 025004. doi: 10.1088/1748-605X/acb02e
Schäfer H, Subbarayan K, Massa C, Vaxevanis C, Mueller A, Seliger B. Correlation of the tumor escape phenotype with loss of PRELP expression in melanoma. J Transl Med 2023, 21, article 643. doi: 10.1186/s12967-023-04476-x
Schimmelpfennig C, Rade M, Füssel S, Löffler D, Blumert C, Bertram C, Borkowetz A, Otto D J, Puppel S-H, Hönscheid P, Sommer U, Baretton G B, Köhl U, Wirth M, Thomas C, Horn F, Kreuz M, Reiche K. Characterization and evaluation of gene fusions as a measure of genetic instability and disease prognosis in prostate cancer. BMC Cancer 2023, 23, article 575. doi: 10.1186/s12885-023-11019-6
Schmidt J R, Haupt J, Riemschneider S, Kämpf C, Löffler D, Blumert C, Reiche K, Koehl U, Kalkhof S, Lehmann J. Transcriptomic signatures reveal a shift towards an anti-inflammatory gene expression profile but also the induction of type I and type II interferon signaling networks through aryl hydrocarbon receptor activation in murine macrophages. Front Immunol 2023, 14: article number 1156493. doi: 10.3389/fimmu.2023.1156493
Schulz J, Schilling E, Fabian C, Zenclussen A C, Stojanovska V, Claus C. Dissecting rubella placental infection in an In vitro trophoblast model. Int J Mol Sci, 2023, 24(9), article number 7894. doi: 10.3390/ijms24097894
Szardenings M, Delaroque N, Kern K, Ramirez-Caballero L, Puder M, Ehrentreich-Förster E, Beige J, Zürner S, Popp G, Wolf J, Borte S. Detection of antibodies against endemic and SARS-CoV-2 coronaviruses with short peptide epitopes. Vaccines 2023, 11 (9), article 1403, doi: 10.3390/vaccines11091403
Tan K, Jäger C, Geissler S, Schlenzig D, Buchholz M, Ramsbeck D. Synthesis and structure–activity relationships of pyrazole-based inhibitors of meprin α and β. J Enzyme Inhib Med Chem. 2023, 38 (1): 2165648. doi: 10.1080/14756366.2023.2165648
Tanuchai B, Ji L, Schröder O, Gawol S J, Geissler A, Wahdan S F M, Buscot F, Kalkhof S, Schulze E-D, Noll M, Purahong W. Fate of a biodegradable plastic in forest soil: dominant tree species and forest types drive changes in microbial community assembly, influence the composition of plastisphere, and affect poly(butylene succinate-co-adipate) degradation. Sci Total Environ 2023, 873: article 162230. doi: 10.1016/j.scitotenv.2023.162230
Thaher B A, Al-Masri I, Wahedy K, Morjan R, Aliwaini S, Al atter I M, Elmabhouh A A, Al Ibwaini A K, Alkhaldi S L, Qeshta B, Jacob C, Deigner H-P. Synthesis and bioassay of 3-Aryl -1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]- triazin-4(3H)-ones as anti-cancer agents. Naunyn Schmiedebergs Arch Pharmacol. 2023, 396(8): 1797-1810. doi: 10.1007/s00210-023-02433-5
Tong L, Kremer V, Neo SY, Liu Y, Chen Y, Wagner AK, Yang Y, Chen Z, Seitz C, Tobin NP, Ligtenberg MA, Alici E, Chen X, Haglund F, Seliger B, Harmenberg U, Colón E, Plogell AS, Liu LL, Lundqvist A. Renal cell carcinoma escapes NK cell-mediated immune surveillance through the downregulation of DNAM-1. Cancer Commun (Lond.) 2023, 43 (7): 855-859. doi: 10.1002/cac2.12446
Vaxevanis C K, Bauer M, Subbarayan K, Friedrich M, Massa C, Biehl K, Al-Ali H K, Wickenhauser C, Seliger B. Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapy. OncoImmunology 2023, 12 (1), article 2152998. doi: 10.1080/2162402X.2022.2152998
Vogelsberg E, Moors M, Sorokina A S, Ryndyk D A, Schmitz S, Freitag J S, Subbotina A V, Heine T, Abel B, Monakhov K Y. Solution-processed formation of DNA-origami-supported polyoxometalate multi-level Switches with countercation-controlled conductance tunability. Chem Mater 2023, 35 (14). doi: 10.1021/acs.chemmater.3c00776
Wang N, Lei T, Zhu Y, Li Y, Cai H, Zhang P, Leptihn S, Zhou J, Ke H, Gao B, Feng Y, Hua X, Qu T. Characterization of two novel VIM-type metallo-β-lactamases, VIM-84 and VIM-85, associated with the spread of IncP-2 megaplasmids in Pseudomonas aeruginosa. Microbiol Spectr 2023, 11 (5), article e0154423. doi: 10.1128/spectrum.01544-23
Wang Y, He J, Sun L, Jiang Y, Hu L, Leptihn S, Zhu P, Fu X, Yu Y, Hua X. IS26 mediated blaCTX-M-65 amplification in Escherichia coli increase the antibiotic resistance to cephalosporin in vivo. J Glob Antimicrob Resist 2023, 35: 202-209. doi: 10.1016/j.jgar.2023.09.018
Wang Y, Jasinski-Bergner S, Wickenhauser C, Seliger B. Cancer immunology: immune escape of tumors - expression and regulation of HLA class I molecules and its role in immunotherapies. Adv Anat Pathol 2023, 30 (3): 148-159. doi: 10.1097/PAP.0000000000000389
Weiß R, Issmail L, Rockstroh A, Grunwald T, Fertey J, Ulbert S. Immunization with different recombinant West Nile virus envelope proteins induces varying levels of serological cross-reactivity and protection from infection. Front Cell Infect Microbiol, 2023, 13: 1279147. doi: 10.3389/fcimb.2023.1279147
Zhang X, Greiser S, Roy U, Lange F, Gorkum R v, Fournelle M, Speicher D, Tretbar S, Melzer A, Landgraf L. Evaluation of a developed MRI-guided focused ultrasound system in 7 T small animal MRI and proof-of-concept in a prostate cancer xenograft model to improve radiation therapy. Cells 2023, 12 (3), article 481, doi: 10.3390/cells12030481

Publikationen 2022

Alaneed R, Naumann M, Pietzsch M, Kressler J. Microbial transglutaminase-mediated formation of erythropoietin-polyester conjugates. J Biotechnol. 2022 Feb 20;346:1-10. doi: 10.1016/j.jbiotec.2022.01.001. Epub 2022 Jan 15.
Allelein S, Aerchlimann K A, Roesch G, Khajehamiri R, Koelsch A, Freese C, Kuhlmeier D. Prostate-specific membrane antigen (PSMA)-positive extracellular vesicles in urine - a potential liquid biopsy strategy for prostate cancer diagnosis? Cancers (Basel). 2022 Jun 17;14(12):2987. doi: 10.3390/cancers14122987
Arbaciauskaite S, Babakhani P, Sandetskaya N, Vitkus D, Jancoriene L, Karosiene D, Karciauskaite D, Zablockiene B, Kuhlmeier D. Self-sampled gargle water direct RT-LAMP as a screening method for the detection of SARS-CoV-2 infections. Diagnostics (Basel). 2022 Mar 22;12(4):775. doi: 10.3390/diagnostics12040775
Arteaga V G, Demand V, Kern K, Strube A, Szardenings M, Muranyi I, Eisner P, Schweiggert-Weisz U. Enzymatic hydrolysis and fermentation of pea protein isolate and its effects on antigenic proteins, functional properties, and sensory profile. Foods. 2022 Jan 4;11(1):118. doi: 10.3390/foods11010118
Arumugam S N, Manohar P, Sukumaran S, Sadagopan S, Loh B, Leptihn S, Nachimuthu R. Antibacterial efficacy of lytic phages against multidrug-resistant Pseudomonas aeruginosa infections in bacteraemia mice models. BMC Microbiol. 2022 Aug 1;22(1):187. doi: 10.1186/s12866-022-02603-0
Bathini P, Sun T, Schenk M, Schilling S, McDannold N J, Lemere C A. Acute effects of focused ultrasound-induced blood-brain barrier opening on anti-pyroglu3 abeta antibody delivery and immune responses. Biomolecules. 2022 Jul 6;12(7):951. doi: 10.3390/biom12070951
Bäumer N, Scheller A, Wittmann L, Faust A, Apel M, Nimmagadda SC, Geyer C, Grunert K, Kellmann N, Peipp M, Kailayangiri S, Ezequiel Gutierrez Suburu ME, Strassert CA, Schenk M, Greune L, Rüter C, Dersch P, Hartmann W, Rossig C, Neri D, Müller-Tidow C, Schwöppe C, Schliemann C, Khandanpour C, Lenz G, Berdel WE, Bäumer S. Electrostatic anti-CD33-antibody-protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia. J Hematol Oncol. 2022 Dec 1;15(1):171. doi: 10.1186/s13045-022-01390-5
Bayly-Jones C, Lupton C J, Fritz C, Venugopal H, Ramsbeck D, Wermann M, Jaeger C, Marco A de, Schiling S, Schlenzig D, Whisstock J C. Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor. Nat Commun. 2022 Oct 19;13(1):6178. doi: 10.1038/s41467-022-33893-7
Beckmann L, Tretbar S, Kitte R, Tretbar M. Anticancer activity of natural and semi-synthetic drimane and coloratane sesquiterpenoids. Molecules. 2022 Apr 13;27(8):2501. doi: 10.3390/molecules27082501
Berneck B S, Rockstroh A, Barzon L, Sinigaglia A, Vocale C, Landini M P, Rabenau H F, Schmidt-Chanasit J, Ulbert S. Serological differentiation of West Nile virus- and Usutu virus-induced antibodies by envelope proteins with modified cross-reactive epitopes. Transbound Emerg Dis. 2022 Sep;69(5):2779-2787. doi: 10.1111/tbed.14429. Epub 2022 Jan 10
Beyer K, Straten V, Remmers S, MacLennan S, MacLennan S, Gandaglia G, Willemse P-P M, Herrera R, Omar M I, Russel B, Huber J, Kreuz M, Asiimwe A, Abbott T, Briganti A, Hemelrijck M van, Roobol M J, Prias Consortium, Erspc Rotterdam Study Group, Pioneer Consortium. Secondary treatment for men with localized prostate cancer: a pooled analysis of PRIAS and ERSPC-Rotterdam data within the PIONEER data platform. J Pers Med. 2022 May 5;12(5):751. doi: 10.3390/jpm12050751
Biadglegne F, Schmidt J R, Engel K M, Lehmann J, Lehmann R T, Reinert A, Koenig B, Schiller J, Kalkhof S, Sack U. Mycobacterium tuberculosis affects protein and lipid content of circulating exosomes in infected patients depending on Tuberculosis disease state. Biomedicines. 2022 Mar 27;10(4):783. doi: 10.3390/biomedicines10040783
Blache U, Ford EM, Ha B, Rijns L, Dankers PYW, Kloxin AM, Snedeker JG, Gentleman E. Engineered hydrogels for mechanobiology. Nature Reviews Methods Primer 2 (2022)
Blache U, Popp G, Duenkel A, Koehl U, Fricke S. Potential solutions for manufacture of CAR T cells in cancer immunotherapy. Nat Commun. 2022 Sep 5;13(1):5225. doi: 10.1038/s41467-022-32866-0
Bluhm A, Schrempel S, Moceri S, Stieler J, Feja M, Schilling S, Schulze A, Hörsten S von, Hartlage-Rübsamen M, Richter F, Roßner S. Alpha synuclein processing by MMP-3 - implications for synucleinopathies. Behav Brain Res. 2022 Sep 26;434:114020. doi: 10.1016/j.bbr.2022.114020. Epub 2022 Jul 21
Bluhm A, Schrempel S, Schilling S, Hoersten, S von, Schulze A, Roßner S, Hartlage-Ruebsamen M. Immunohistochemical demonstration of the pGlu79 α-synuclein fragment in Alzheimer’s disease and its Tg2576 mouse model. Biomolecules. 2022 Jul 20;12(7):1006. doi: 10.3390/biom12071006
Borgolte M, Quint I, Kaiser L, Csuk R, Deigner H-P. A fluorescence-based competitive antibody binding assay for kynurenine, a potential biomarker of kidney transplant failure. Diagnostics (Basel). 2022 Jun 2;12(6):1380. doi: 10.3390/diagnostics12061380
Borgolte M, Riester O, Quint I, Blendinger F, Bucher V, Laufer S, Csuk R, Scotti L, Deigner H-P. Synthesis of a biocompatible benzophenone-substituted chitosan hydrogel as novel coating for PEEK with extraordinary strong antibacterial and anti-biofilm properties. Materials today chemistry 26 (2022), 101176. doi: 10.1016/j.mtchem.2022.101176
Dienelt A, Keller K C, Zur Nieden N. High glucose impairs osteogenic differentiation of embryonic stem cells via early diversion of beta‐catenin from Forkhead box O to T cell factor interaction. Birth Defects Res. 2022 Oct 1;114(16):1056-1074. doi: 10.1002/bdr2.2085. Epub 2022 Sep 26
Donnadieu E , Luu M, Alb M, Anliker B, Arcangeli S, Bonini C, De Angelis B, Choudhary R, Espie D, Galy A, Holland C, Ivics Z, Kantari-Mimoun C, Kersten M J, Koehl U, Kuhn C, Laugel B, Locatelli F, Marchiq I, Markman J, Moresco M A, Morris E, Negre H, Quintarelli C, Rade M, Reiche K, Renner M, Ruggiero E, Sanges C, Stauss H, Themeli M, Van den Brulle J, Hudecek M, Casucci M. Time to evolve: predicting engineered T cell-associated toxicity with next-generation models. J Immunother Cancer. 2022 May;10(5):e003486. doi: 10.1136/jitc-2021-003486
Doß S, Blessing C, Haller K, Richter G, Sauer M. Influence of antibiotics on functionality and viability of liver cells in vitro. Curr Issues Mol Biol. 2022 Oct 3;44(10):4639-4657. doi: 10.3390/cimb44100317
Elbalasy I, Wilharm N, Herchenhahn E, Konieczny R, Mayr S G, Schnauß J. From strain stiffening to softening - rheological characterization of keratins 8 and 18 networks crosslinked via electron irradiation. Polymers (Basel). 2022 Feb 4;14(3):614. doi: 10.3390/polym14030614
Finkensieper J, Issmail L, Fertey J, Rockstroh A, Schopf S, Standfest B, Thoma M, Grunwald T, Ulbert S. Low-energy electron irradiation of tick-borne encephalitis virus provides a protective inactivated vaccine. Front Immunol. 2022 Mar 7;13:825702. doi: 10.3389/fimmu.2022.825702. eCollection 2022
Friedrich M, Aigner A. Therapeutic siRNA: state-of-the-art and future perspectives. BioDrugs. 2022 Sep;36(5):549-571. doi: 10.1007/s40259-022-00549-3. Epub 2022 Aug 23
Friedrich M, Pfeifer G, Binder S, Aigner A, Barbosa P V, Makert G R, Fertey J, Ulbert S, Bodem J, Koenig E-M, Geiger N, Schambach A, Schilling E, Buschmann T, Hauschildt S, Koehl U, Sewald K. Selection and validation of siRNAs preventing uptake and replication of SARS-CoV-2. Front Bioeng Biotechnol. 2022 Mar 2;10:801870. doi: 10.3389/fbioe.2022.801870. eCollection 2022
Fueldner C, Riemschneider S, Haupt J, Jungnickel H, Schulze F, Zoldan K, Esser C, Hauschildt S, Knauer J, Luch A, Kalkhof S, Lehmann J. Aryl hydrocarbon receptor activation by Benzo[a]pyrene prevents development of septic shock and fatal outcome in a mouse model of systemic Salmonella enterica infection. Cells. 2022 Feb 20;11(4):737. doi: 10.3390/cells11040737
Furesi G, Jesus Domingues A M, Alexopoulou D, Dahl A, Hackl M, Schmidt J, Kalkhof S, Kurth T, Taipaleenmaeki H, Conrad S, Hofbauer C, Rauner M, Hofbauer L C. Exosomal miRNAs from prostate cancer impair osteoblast function in mice. Int J Mol Sci. 2022 Jan 24;23(3):1285. doi: 10.3390/ijms23031285
Glienke W, Dragon A C, Zimmermann K, Martyniszyn-Eiben A, Mertens M, Abken H, Rossig C, Altvater B, Aleksandrova K, Arseniev L, Kloth C, Stamopoulou A, Moritz T, Lode H N, Siebert N, Blasczyk R, Goudeva L, Schambach A, Koehl U, Eiz-Vesper B, Esser R. GMP-compliant manufacturing of TRUCKs: CAR T cells targeting GD2 and releasing inducible IL-18. Front Immunol. 2022 Mar 24;13:839783. doi: 10.3389/fimmu.2022.839783. eCollection 2022
Gnoth K, Geissler S, Feldhaus J, Taudte N, Ilse V, Zürner S, Greiser S, Braumann U-D, Rahfeld J-U, Cynis H, Schilling S. Evidence for enhanced efficacy of passive immunotherapy against beta-amyloid in CD33-negative 5xFAD mice. Biomolecules. 2022 Mar 4;12(3):399. doi: 10.3390/biom12030399
Gringmuth M, Walther J, Greiser S, Toussaint M, Schwalm B, Kool M, Kortmann R-D, Glasow A, Patties I. Enhanced survival of high-risk medulloblastoma-bearing mice after multimodal treatment with radiotherapy, decitabine, and abacavir. Int J Mol Sci. 2022 Mar 30;23(7):3815. doi: 10.3390/ijms23073815
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Heggli I, Blache U, Herger N, Mengis T, Jaeger PK, Schupbach R, Farshad-Amacker N, Brunner F, Snedeker JG, Farshad M, Distler O, Dudlis S. FGF2 overrides key pro-fibrotic features of bone marrow stromal cells isolated from Modic type 1 change patients. Eur Cell Mater. 2022 Oct 18;44:101-114. doi: 10.22203/eCM.v044a07
Hoen L, Rudisch C, Wick M, Indenbirken M, Grundhoff A, Wegwitz F, Kalkhof S, Hildebrand J. Osmotic stress interferes with DNA damage response and H2AX phosphorylation in human keratinocytes. Cells. 2022 Mar 11;11(6):959. doi: 10.3390/cells11060959
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Ilse V, Scholz R, Wermann M, Naumann M, Staege M S, Roßner S, Cynis H. Immunogenicity of the envelope surface unit of human endogenous retrovirus K18 in mice. Int J Mol Sci. 2022 Jul 28;23(15):8330. doi: 10.3390/ijms23158330
Issmail L, Möser C, Jäger C, Altattan B, Ramsbeck D, Kleinschmidt M, Buchholz M, Smith D, Grunwald T. Prefusion-specific antibody-derived peptides trivalently presented on DNA-nanoscaffolds as an innovative strategy against RSV entry. Frontiers in Virology (2022). doi: 10.3389/fviro.2022.994843
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Jasinski-Bergner S, Bluemke J, Bauer M, Skiebe S L, Mandelboim O, Wickenhauser C, Seliger B. Novel approach to identify putative Epstein–Barr–virus microRNAs regulating host cell genes with relevance in tumor biology and immunology. Oncoimmunology. 2022 May 1;11(1):2070338. doi: 10.1080/2162402X.2022.2070338. eCollection 2022
Jasinski-Bergner S, Eckstein M, Taubert H, Wach S, Fiebig C, Strick R, Hartmann A, Seliger B. The human leukocyte antigen G as an immune escape mechanism and novel therapeutic target in urological tumors. Front Immunol. 2022 Feb 3;13:811200. doi: 10.3389/fimmu.2022.811200. eCollection 2022
Jasinski-Bergner S, Schmiedel D, Mandelboim O, Seliger B. Role of HLA-G in viral infections. Front Immunol. 2022 Feb 14;13:826074. doi: 10.3389/fimmu.2022.826074. eCollection 2022
Jiao Z, Han Y, Zhao J, Chao Z, Tárnok A, You Z. Rapid switching and durable on-chip spark-cavitation-bubble cell sorter. Microsyst Nanoeng. 2022 May 18;8:52. doi: 10.1038/s41378-022-00382-2. eCollection 2022
Kaniowska D, Wenk K, Rademacher P, Weiss R, Fabian C, Schulz I, Guthardt M, Lange F, Greiser S, Schmidt M, Braumann U-D, Emmrich F, Koehl U, Jaimes Y. Extracellular Vesicles of Mesenchymal Stromal Cells Can be Taken Up by Microglial Cells and Partially Prevent the Stimulation Induced by β-amyloid Stem Cell. Rev Rep. 2022 Mar;18(3):1113-1126. doi: 10.1007/s12015-021-10261-4. Epub 2022 Jan 26
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Kruse M, Moeser C, Smith D M, Mueller-Landau H, Rant U, Hoelzel R, Bier F F. Measuring Influenza A virus and peptide interaction using electrically controllable DNA nanolevers. Advanced materials technologies 7 (2022), 5, 2101141, 11 Seiten. doi: 10.1002/admt.202101141
Leptihn S, Loh B W-C. Complexity, challenges and costs of implementing phage therapy. Future Microbiol. 2022 Jun;17:643-646. doi: 10.2217/fmb-2022-0054. Epub 2022 Apr 11
Liu M, Tian Y, Zaki H E M, Ahmed T, Yao R, Yan C, Leptihnm S, Loh B, Shahid M S, Wang F, Chen J, Li B. Phage resistance reduced the pathogenicity of Xanthomonas oryzae pv. oryzae on rice. Viruses. 2022 Aug 13;14(8):1770. doi: 10.3390/v14081770
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Loeffler-Wirth H, Rade M, Arakelyan A, Kreuz M, Loeffler M, Koehl U, Reiche K, Binder H. Transcriptional states of CAR-T infusion relate to neurotoxicity - lessons from high-resolution single-cell SOM expression portraying. Front Immunol. 2022 Sep 28;13:994885. doi: 10.3389/fimmu.2022.994885. eCollection 2022
Manohar P, Loganathan A, Nachimuthu R, Loh B, Ma L, Turner D, Leptihn S. Complete Genome Sequence of Pseudomonas Phage Motto. Microbiol Resour Announc. 2022 Nov 17;11(11):e0074022. doi: 10.1128/mra.00740-22. Epub 2022 Oct 12
Massa C, Seliger B. Enhanced function of vaccine dendritic cells from obese donors upon inhibition of the lipid metabolism. Clin Transl Med. 2022 Feb;12(2):e557. doi: 10.1002/ctm2.557
Nachimuthu R, Manohar P, Eniyan K, Archana L, Athira S, Loh B, Ma L, Leptihn S. A lysozyme murein hydrolase with broad-spectrum antibacterial activity from Enterobacter phage myPSH1140. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0050622. doi: 10.1128/aac.00506-22. Epub 2022 Aug 11
Nagel M, Moretti R, Paschke R, Bergen M, Meiler J, Kalkhof S. Integrative model of the FSH receptor reveals the structural role of the flexible hinge region. Structure. 2022 Oct 6;30(10):1424-1431.e3. doi: 10.1016/j.str.2022.07.007. Epub 2022 Aug 15
Nickel O, Rockstroh A, Borte S, Wolf J. Evaluation of simple lateral flow immunoassays for detection of SARS-CoV-2 neutralizing antibodies. Vaccines (Basel). 2022 Feb 23;10(3):347. doi: 10.3390/vaccines10030347
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Oberbach A, Schlichting N, Hagl C, Lehmann S, Kullnick Y, Friedrich M, Köhl U, Horn F, Kumbhari V, Löffler B, Schmidt F, Joskowiak D, Born F, Saha S, Bagaev E. Four decades of experience of prosthetic valve endocarditis reflect a high variety of diverse pathogens. Cardiovasc Res. 2022 Apr 14;cvac055. doi: 10.1093/cvr/cvac055. Online ahead of print
Peter A S, Roth E, Schulz S R, Fraedrich K, Steinmetz T, Damm D, Hauke M, Richel E, Mueller-Schmucker S, Habenicht K, Eberlein V, Issmail L, Uhlig N, Dolles S, Gruener E, Peterhoff D, Ciesek S, Hoffmann M H, Poehlmann S, McKay P F, Shattock R J, Woelfel R, Socher E, Wagner R, Eichler J, Sticht H, Schuh W, Neipel F, Ensser A, Mielenz D, Tenbusch M, Winkler T H, Grunwald T, Überla K, Jäck H-M. A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model. Eur J Immunol. 2022 May;52(5):770-783. doi: 10.1002/eji.202149374. Epub 2021 Sep 13
Poh P S, Lingner T, Kalkhof S, Maerdian S, Baumbach J, Dondl P, Duda G N, Checa S. Enabling technologies towards personalization of scaffolds for large bone defect regeneration. Curr Opin Biotechnol. 2022 Apr;74:263-270. doi: 10.1016/j.copbio.2021.12.002. Epub 2022 Jan 7
Ramírez Caballero L, Treudler R,Delaroque N, Simon J C, Kern K, Szardenings M. Peptide epitopes as biomarkers of soya sensitization in rBet v 1 immunotherapy of birch‐related soya allergy. Clin Exp Allergy. 2022 Sep 14. doi: 10.1111/cea.14224. Online ahead of print
Reiber M, Koska I, Pace C, Schoenhoff K, Schumann L von, Palme R, Potschka H. Development of behavioral patterns in young C57BL/6J mice: a home cage-based study. Sci Rep. 2022 Feb 15;12(1):2550. doi: 10.1038/s41598-022-06395-1
Richter A, Seidel R W, Goddard R, Eckhardt T, Lehmann C, Doerner J, Siersleben F, Sondermann T, Mann L, Patzer M, Jaeger C, Reiling N, Imming P. BTZ-derived benzisothiazolinones with in vitro activity against mycobacterium tuberculosis. ACS Med Chem Lett. 2022 Jul 25;13(8):1302-1310. doi: 10.1021/acsmedchemlett.2c00215. eCollection 2022 Aug 11
Riester O, Burkhardtsmaier P, Gurung Y, Laufer S, Deigner H-P, Schmidt M S. Synergy of R-(-)carvone and cyclohexenone-based carbasugar precursors with antibiotics to enhance antibiotic potency and inhibit biofilm formation. Sci Rep. 2022 Oct 26;12(1):18019. doi: 10.1038/s41598-022-22807-8
Ritter P, Cai A, Reischl B, Fiedler M, Prols G, Fries B, Kretzschmar E, Michael M, Hartmann K, Lesko C, Salti H, Arkudas A, Horch R, Paulsen F, Friedrich O, Haug M. MyoBio: an automated bioreactor system technology for standardized perfusion-decellularization of whole skeletal muscle. IEEE Trans Biomed Eng. 2022 Jul;69(7):2305-2313. doi: 10.1109/TBME.2022.3142317. Epub 2022 Jun 17
Ruppel K, Fricke S, Koehl U, Schmiedel D. Taking lessons from CAR-T cells and going beyond: tailoring design and signaling for CAR-NK cells in cancer therapy. Front Immunol. 2022 Mar 18;13:822298. doi: 10.3389/fimmu.2022.822298. eCollection 2022
Saha S, Ali A, Schnackenburg P, Horke K M, Oberbach A, Schlichting N, Sadoni S, Rizas K, Braun D, Luehr M, Bagaev E, Hagl C, Joskowiak D. Surgery for aortic prosthetic valve endocarditis in the transcatheter era. J Clin Med. 2022 Jun 14;11(12):3418. doi: 10.3390/jcm11123418
Saliba F, Bañaras R, Larsen F S, Wilmer A, Parés A, Mitzner S, Stange J, Fuhrmann V, Gilg S, Hassanein T, Samuel D, Torner J, Jaber S. Artificial liver support in patients with liver failure: a modified DELPHI consensus of international experts. Intensive Care Med. 2022 Oct;48(10):1352-1367. doi: 10.1007/s00134-022-06802-1. Epub 2022 Sep 6
Schaffert A, Karkossa I, Ueberham E, Schlichting R, Walter K, Arnold J, Blüher M, Heiker J T, Lehmann J, Wabitsch M, Escher B I, Bergen M, Schubert K. Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes. Environ Int. 2022 Jun;164:107279. doi: 10.1016/j.envint.2022.107279. Epub 2022 May 6
Schary W, Paskali F, Rentschler S, Ruppert C, Wagner G E, Steinmetz I, Deigner H-P, Kohl M. Open-source, adaptable, all-in-one smartphone-based system for quantitative analysis of point-of-care diagnostics. Diagnostics (Basel). 2022 Feb 25;12(3):589. doi: 10.3390/diagnostics12030589
Schilling E, Pfeiffer L, Hauschildt S, Koehl U, Claus C. CD14 Is involved in the Interferon response of human macrophages to Rubella virus infection. Biomedicines. 2022 Jan 26;10(2):266. doi: 10.3390/biomedicines10020266
Seliger B, Al-Samadi A, Yang B, Salo T, Wickenhauser C. In vitro models as tools for screening treatment options of head and neck cancer. Front Med (Lausanne). 2022 Sep 7;9:971726. doi: 10.3389/fmed.2022.971726. eCollection 2022
Seliger B, Jasinski-Bergner S, Massa C, Mueller A, Biehl K, Yang B, Bachmann M, Jonigk D, Eichhorn P, Hartmann A, Wickenhauser C, Bauer M. Induction of pulmonary HLA-G expression by SARS-CoV-2 infection. Cell Mol Life Sci. 2022 Nov 5;79(11):582. doi: 10.1007/s00018-022-04592-9
Seliger B, Koehl U. Underlying mechanisms of evasion from NK cells as rationale for improvement of NK cell-based immunotherapies. Front Immunol. 2022 Aug 12;13:910595. doi: 10.3389/fimmu.2022.910595. eCollection 2022
Seliger B, Massa C. Modulation of lymphocyte functions in the microenvironment by tumor oncogenic pathways. Front Immunol. 2022 May 19;13:883639. doi: 10.3389/fimmu.2022.883639. eCollection 2022
Semwala R, Semwal R B, Lehmann J, Semwal D K. Recent advances in immunotoxicity and its impact on human health: causative agents, effects and existing treatments. Int Immunopharmacol. 2022 Jul;108:108859. doi: 10.1016/j.intimp.2022.108859. Epub 2022 May 19
Spukti F F, Schnauß J. Large and stable: actin aster networks formed via entropic forces. Front Chem. 2022 Aug 25;10:899478. doi: 10.3389/fchem.2022.899478. eCollection 2022
Stegmann K M, Dickmanns A, Heinen N, Blaurock C, Karrasch T, Breithaupt A, Klopffleisch R, Uhlig N, Eberlein V, Issmail L, Herrmann S T, Schreieck A, Peelen E, Kohlhof H, Sadeghi B, Riek A, Speakman J R, Groß U, Goerlich D, Vitt D, Mueller T, Grunwald T, Pfaender S, Balkema-Buschmann A, Dobbelstein M. Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication. iScience. 2022 May 20;25(5):104293. doi: 10.1016/j.isci.2022.104293. Epub 2022 Apr 25
Strobelt R, Adler J, Paran N, Yahalom-Ronen Y, Melamed S, Politi B, Shulman Z, Schmiedel D, Shaul Y. Imatinib inhibits SARS-CoV-2 infection by an off-target-mechanism. Sci Rep. 2022 Apr 6;12(1):5758. doi: 10.1038/s41598-022-09664-1
Subbarayan K, Massa C, Leisz S, Steven A, Bethmann D, Biehl K, Wickenhauser C, Seliger B. Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells. Oncoimmunology. 2022 Apr 28;11(1):2069214. doi: 10.1080/2162402X.2022.2069214. eCollection 2022
Subirana M A, Riemschneider S, Hause G, Dobritzsch D, Schaumloeffel D, Herzberg M. High spatial resolution imaging of subcellular macro and trace element distribution during phagocytosis. Metallomics. 2022 Apr 1;14(4):mfac011. doi: 10.1093/mtomcs/mfac011
Taha A, Bobi J, Dammers R, Dijkhuizen R M, Dreyer A Y, Es A C G M, Ferrara F, Gounis M J, Nitzsche B, Platt S, Stoffel M H, Volovici V, Zoppo G J, Duncker D J, Dippel D W J, Boltze J, Beusekom H M M. Comparison of large animal models for acute ischemic stroke: which model to use? Stroke. 2022 Apr;53(4):1411-1422. doi: 10.1161/STROKEAHA.121.036050. Epub 2022 Feb 15
Toma G, Karapetian E, Massa C, Quandt D, Seliger B. Characterization of the effect of histone deacetylation inhibitors on CD8+ T cells in the context of aging. J Transl Med. 2022 Nov 22;20(1):539. doi: 10.1186/s12967-022-03733-9
Toma G, Lemnian IM, Karapetian E, Grosse I, Seliger B. Transcriptional Analysis of Total CD8+ T Cells and CD8+CD45RA- Memory T Cells From Young and Old Healthy Blood Donors. Front Immunol. 2022 Jan 27;13:806906. doi: 10.3389/fimmu.2022.806906. eCollection 2022
Wagner D L, Koehl U, Chmielewski M, Scheid C, Stripecke R. Review: sustainable clinical development of CAR-T cells - switching from viral transduction towards CRISPR-Cas gene editing. Front Immunol. 2022 Jun 17;13:865424. doi: 10.3389/fimmu.2022.865424. eCollection 2022
Weil T, Kirupakaran A, Le M-H, Rebmann P, Mieres-Perez J, Issmail L, Conzelmann C, Mueller J A, Rauch L, Gilg A, Wettstein L, Groß R, Read C, Bergner T, Axberg Pålsson S, Uhlig N, Eberlein V, Woell H, Klaerner F-G, Stenger S, Kuemmerer B M, Streeck H, Fois G, Frick M, Braubach P, Spetz A-L, Grunwald T, Shorter J, Sanchez-Garcia E, Schrader T, Muench J. Advanced molecular tweezers with lipid anchors against SARS-CoV-2 and other respiratory viruses. JACS Au. 2022 Sep 6;2(9):2187-2202. doi: 10.1021/jacsau.2c00220. eCollection 2022 Sep 26
Werner M, Dyas A, Parfentev I, Schmidt G E, Mieczkowska I K, Mueller-Kirschbaum L C, Mueller C, Kalkhof S, Reinhardt O, Urlaub H, Alves F, Gallwas J, Prokakis E, Wegwitz F. ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness. Cell Death Dis. 2022 Sep 3;13(9):762. doi: 10.1038/s41419-022-05197-7
Zhang L, Wang X, Hua X, Yu Y, Lepthin S, Loh B. Therapeutic evaluation of the Acinetobacter baumannii phage Phab24 for clinical use. Virus Res. 2022 Oct 15;320:198889. doi: 10.1016/j.virusres.2022.198889. Epub 2022 Aug 12

Publikationen 2021

Ahlhelm M, Latorre S H, Mayr H O, Storch C, Freytag C, Werner D, Schwarzer-Fischer E, Seidenstücker M. Mechanically stable β-TCP structural hybrid scaffolds for potential bone replacement. J. Compos. Sci. 5 (2021), 10, 281. doi: 10.3390/jcs5100281
Allelein S, Medina-Perez P, Heitor Lopes A L, Rau S, Hause G, Kölsch A, Kuhlmeier D. Potential and challenges of specifically isolating extracellular vesicles from heterogeneous populations. Sci Rep. (2021) , 11, 11585. doi: 10.1038/s41598-021-91129-y
Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H, Jassoy C. A review of the toxicity and phytochemistry of Medicinal plant species used by herbalists in treating people living with HIV/AIDS in Uganda. Front Pharmacol. (2021), 12, 615147. doi: 10.3389/fphar.2021.615147
Bauer M, Vaxevanis C, Al-Ali H K, Jaekel N, Le Hoa Naumann C, Schaffrath J, Rau A, Seliger B, Wickenhauser C. Altered spatial composition of the immune cell repertoire in association to CD34+ blasts in myelodysplastic syndromes and secondary acute myeloid leukemia. Cancers (Basel).13 (2021), 2, 186. doi: 10.3390/cancers13020186
Berneck BS, Rockstroh A, Barzon L, Sinigaglia A, Vocale C, Landini MP, Rabenau HF, Schmidt-Chanasit J, Ulbert S. Serological differentiation of West Nile virus- and Usutu virus-induced antibodies by envelope proteins with modified cross-reactive epitopes. Transbound Emerg Dis. (2021) Dec 16. doi: 10.1111/tbed.14429
Berto C, Krajcarz M T, Hoyo M, Komar M, Sinet-Mathiot V, Zarzecka-Szubinska K, Krajcarz M, Szymanek M, Wertz K, Marciszak A, Metrak M, Suska-Malawska M, Wilcke A, Kot M. Environment changes during middle to upper palaeolithic transition in southern Poland (Central Europe) : a multiproxy approach for the MIS 3 sequence of Koziarnia Cave (Kraków-Częstochowa Upland). Journal of archaeological science reports 35 (2021), 102723. doi: 10.1016/j.jasrep.2020.102723
Bialek-Waldmann JK, Domning S, Esser R, Glienke W, Mertens M, Aleksandrova K, Arseniev L, Kumar S, Schneider A, Koenig J, Theobald SJ, Tsay HC, Cornelius ADA, Bonifacius A, Eiz-Vesper B, Figueiredo C, Schaudien D, Talbot SR, Bleich A, Spineli LM, von Kaisenberg C, Clark C, Blasczyk R, Heuser M, Ganser A, Köhl U, Farzaneh F, Stripecke R. Induced dendritic cells co-expressing GM-CSF/IFN-α/tWT1 priming T and B cells and automated manufacturing to boost GvL. Mol Ther Methods Clin Dev. (2021) 21, Seite 621-641. doi: 10.1016/j.omtm.2021.04.004
Binder S, Zipfel I, Müller C, Wiedemann K, Schimmelpfennig C, Pfeifer G, Reiche K, Hauschildt S, Lehmann J, Köhl U, Horn F, Friedrich M. The noncoding RNA LINC00152 conveys contradicting effects in different glioblastoma cells. Sci Rep. (2021), 11, 18499. doi: 10.1038/s41598-021-97533-8
Bitar M, Boettcher M, Boldt A, Hauck F, Köhl U, Liebert UG, Magg T, Schulz MS, Sack U. Flow cytometric measurement of STAT5 phosphorylation in cytomegalovirus-stimulated T cells. Cytometry A. 99 (2021), 8, Seite 774-783. doi: 10.1002/cyto.a.24286
Blache U, Weiss R, Boldt A, Kapinsky M, Blaudszun AR, Quaiser A, Pohl A, Miloud T, Burgaud M, Vucinic V, Platzbecker U, Sack U, Fricke S, Koehl U. Advanced flow cytometry assays for immune monitoring of CAR-T cell applications. Front Immunol. (2021), 12, 658314. doi: 10.3389/fimmu.2021.658314
Blaess M, Kaiser L, Sommerfeld O, Csuk R, Deigner H-P. Drugs, metabolites, and lung accumulating small lysosomotropic molecules: multiple targeting impedes SARS-CoV-2 infection and progress to COVID-19. Int J Mol Sci. 22 (2021), 4, 1797. doi: 10.3390/ijms22041797
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Publikationen 2020

Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H. Data on medicinal plants used by herbalists for boosting immunity in people living with HIV/AIDS in Uganda. Data in Brief 29 (2020) Artikel-Nr.: 105097, 4 Seiten. dx.doi.org/10.1016/j.dib.2019.105097
Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H. Medicinal plants used by traditional medicine practitioners to boost the immune system in people living with HIV/AIDS in Uganda. European journal of integrative medicine 35 (2020) article 101011. dx.doi.org/10.1016/j.eujim.2019.101011
Ayobahan SU, Eilebrecht S, Baumann L, Teigeler M, Hollert H, Kalkhof S, Eilebrecht E, Schäfers C. Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Chemosphere 240 (2020), 124970. dx.doi.org/10.1016/j.chemosphere.2019.124970
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Zhupanyn P, Ewe A, Büch T, Malek A, Rademacher P, Müller C, Reinert A, Jaimes Y, Aigner A. Extracellular vesicle (ECV)-modified polyethylenimine (PEI) complexes for enhanced siRNA delivery in vitro and in vivo. Journal of controlled release 319 (2020) Seite 63-76. dx.doi.org/10.1016/j.jconrel.2019.12.032

Publikationen 2019

Adamatzky A, Huber F, Schnauß J. Computing on actin bundles network. Scientific Reports 9 (2019), 1, 15887, 10 Seiten. dx.doi.org/10.1038/s41598-019-51354-y
Adamatzky A, Schnauß J, Huber F. Actin droplet machine. Royal Society Open Science 6 (2019), 12, 191135, 16 Seiten. dx.doi.org/10.1098/rsos.191135
Aleksandrova K, Leise J, Priesner C, Melk A, Kubaink F, Abken H, Hombach A, Aktas M, Essl M, Bürger I, Kaiser A, Rauser G, Jurk M, Goudeva L, Glienke W, Arseniev L, Esser R, Köhl U. Functionality and cell senescence of CD4/CD8-selected CD20 CAR T cells manufactured using the automated CliniMACS Prodigy® platform. Transfusion medicine and hemotherapy 45 (2019), 1, Seite 47-54. dx.doi.org/10.1159/000495772
Al-Essa MK, Melzer S, Tárnok A. Two-color analysis of leukocytes labeled by modified RBCs and their fragments. Cytometry Part A 95 (2019), 3, Seite 339-346, dx.doi.org/10.1002/cyto.a.23682
Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H. Indigenous traditional knowledge of medicinal plants used by herbalists in treating opportunistic infections among people living with HIV/AIDS in Uganda. Journal of Ethnopharmacology 246 (2020), article 112205 13 Seiten, dx.doi.org/10.1016/j.jep.2019.112205
Aswal S, Kumar A, Semwal RB, Chauhan A, Kumar A, Lehmann J, Semwal DK. Drimia indica: a plant used in traditional medicine and its potential for clinical uses. Medicina 55 (2019), 6, 16 Seiten, dx.doi.org/10.3390/
medicina55060255
Ayobahan SU, Eilebrecht E, Kotthoff M, Baumann L, Eilebrecht S, Teigeler M, Hollert H, Kalkhof S, Schäfers C. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. Scientific reports 9 (2019), 6599, 12 Seiten. dx.doi.org/10.1038/s41598-019-43089-7
Ayobahan SU, Eilebrecht S, Baumann L, Teigeler M, Hollert H, Kalkhof S, Eilebrecht E, Schäfers C. Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Chemosphere 240 (2020), 124970, 12 Seiten.
dx.doi.org/10.1016/j.chemosphere.2019.124970
Barth M, Gröger V, Cynis H, Staege MS. Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells. Molecular biology reports 46 (2019)2, Seite 1885-1893, dx.doi.org/10.1007/s11033-019-04640-x
Behm LVJ, Gerike S, Grauel MK, Uhlig K, Pfisterer F, Baumann W, Bier FF, Duschl C, Kirschbaum M. Micropatterned thermoresponsive cell culture substrates for dynamically controlling neurite outgrowth and neuronal connectivity in vitro. ACS Applied Bio Mater 7 (2019), 2, 2853-2861. dx.doi.org/10.1021/acsabm.9b00246
Belkum A, Bachmann TT, Lüdke G et al. Developmental roadmap for antimicrobial susceptibility testing systems. Nature Reviews Microbiology 17 (2019), S. 51-62. dx.doi.org/10.1038/s41579-018-0098-9
Bender P, Egger A, Westermann M, Taudte N, Sculean A, Potempa J, Möller B, Buchholz M, Eick S. Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis – a pilot study. Archives of oral biology 97 (2019), January, Seite 223-230, dx.doi.org/10.1016/j.archoralbio.2018.10.022
Bengtsson E, Tárnok A. Special section on image cytometry. Cytometry Part A 95 (2019), 4, Seite 363-365, dx.doi.org/10.1002/cyto.a.23762
Binner C, Wagner J, Schmalz G, Eisner M, Rast J, Kottmann T, Haak R, Oberbach A, Borger MA, Garbade J, Ziebolz D. Insufficient oral behaviour and the high need for periodontal treatment in patients with heart insufficiency and after heart transplantation: a need for special care programs? Journal of Clinical Medicine 8 (2019), 10, Articel 1668, 10 Seiten. dx.doi.org/10.3390/jcm8101668
Bitar M, Boldt A, Freitag MT, Gruhn B, Köhl U, Sack U. Evaluating STAT5 phosphorylation as a mean to assess T cell proliferation. Frontiers in immunology 10 (2019), article 722, 11 Seiten. dx.doi.org/10.3389/fimmu.2019.00722
Blaess M, Deigner HP. Derailed ceramide metabolism in atopic dermatitis (AD): a causal starting point for a personalized (basic) therapy. International journal of molecular sciences 20 (2019), 16, 15 Seiten, dx.doi.org/10.3390/ijms20163967
Bocker HT, Heinrich T, Liebmann L, Hennings JC, Seemann E, Gerth M, Jakovčevski I, Preobraschenski J, Kessels MM, Westermann M, Isbrandt D, Jahn R, Qualmann B, Hübner CA. The Na+/H+ exchanger Nhe1 modulates network excitability via GABA release. Cerebral cortex 13 (2019), 29, Seite 4263-4276, dx.doi.org/10.1093/cercor/bhy308
Bozza FA, Moreira-Soto A, Rockstroh A, Fischer C, Nascimento AD, Calheiros AS, Drosten C, Bozza PT, Souza TML, Ulbert S, Drexler JF. Differential shedding and antibody kinetics of Zika and Chikungunya Viruses, Brazil. Emerging Infectious Diseases 25(2019), 2, Seiten 311-315. dx.doi.org/10.3201/eid2502.180166
Bremm M, Pfeffermann LM, Cappel C, Katzki V1, Erben S, Betz S, Quaiser A, Merker M, Bonig H, Schmidt M, Klingebiel T, Bader P, Huenecke S, Rettinger E. Improving clinical manufacturing of IL-15 activated cytokine-induced killer (CIK) cells. Frontiers in immunology 10 (2019), Artikel 1218, 12 Seiten. dx.doi.org/10.3389/fimmu.2019.01218
Bursch F, Rath KJ, Sarikidi A, Böselt S, Kefalakes E, Osmanovic A, Thau-Habermann N, Klöß S, Köhl U, Petri S. Analysis of the therapeutic potential of different administration routes and frequencies of human mesenchymal stromal cells in the SOD1G93A mouse model of amyotrophic lateral sclerosis. J Tissue Eng Regen Med. 2019 Apr;13(4):649-663. dx.doi.org/10.1002/term.2846. Epub 2019 Mar 20.
Comoli P, Chabannon C, Koehl U, Lanza F, Urbano-Ispizua A, Hudecek M, Ruggeri A, Secondino S, Bonini C, Pedrazzoli P. Development of adaptive immune effector therapies in solid tumors. Ann Oncol. 2019 Nov 1;30(11):1740-1750. dx.doi.org/10.1093/annonc/mdz285
Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andrä I, Annunziato F, Anselmo A, Bacher P, Baldari CT, Bari S, Barnaba V, Barros-Martins J, Battistini L, Bauer W, Baumgart S, Baumgarth N, Baumjohann D, Baying B, Bebawy M, Becher B, Beisker W, Benes V, Beyaert R, Blanco A, Boardman DA, Bogdan C, Borger JG, Borsellino G, Boulais PE, Bradford JA, Brenner D, Brinkman RR, Brooks AES, Busch DH, Büscher M, Bushnell TP, Calzetti F, Cameron G, Cammarata I, Cao X, Cardell SL, Casola S, Cassatella MA, Cavani A, Celada A, Chatenoud L, Chattopadhyay PK, Chow S, Christakou E, Čičin-Šain L, Clerici M, Colombo FS, Cook L, Cooke A, Cooper AM, Corbett AJ, Cosma A, Cosmi L, Coulie PG, Cumano A, Cvetkovic L, Dang VD, Dang-Heine C, Davey MS, Davies D, De Biasi S, Del Zotto G, Dela Cruz GV, Delacher M, Della Bella S, Dellabona P, Deniz G, Dessing M, Di Santo JP, Diefenbach A, Dieli F, Dolf A, Dörner T, Dress RJ, Dudziak D, Dustin M, Dutertre CA, Ebner F, Eckle SBG, Edinger M, Eede P, Ehrhardt GRA, Eich M, Engel P, Engelhardt B, Erdei A, Esser C, Everts B, Evrard M, Falk CS, Fehniger TA, Felipo-Benavent M, Ferry H, Feuerer M, Filby A, Filkor K, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frehse B, Frenette PS, Frischbutter S, Fritzsche W, Galbraith DW, Gangaev A, Garbi N, Gaudilliere B, Gazzinelli RT, Geginat J, Gerner W, Gherardin NA, Ghoreschi K, Gibellini L, Ginhoux F, Goda K, Godfrey DI, Goettlinger C, González-Navajas JM, Goodyear CS, Gori A, Grogan JL, Grummitt D, Grützkau A, Haftmann C, Hahn J, Hammad H, Hämmerling G, Hansmann L, Hansson G, Harpur CM, Hartmann S, Hauser A, Hauser AE, Haviland DL, Hedley D, Hernández DC, Herrera G, Herrmann M, Hess C, Höfer T, Hoffmann P, Hogquist K, Holland T, Höllt T, Holmdahl R, Hombrink P, Houston JP, Hoyer BF, Huang B, Huang FP, Huber JE, Huehn J, Hundemer M, Hunter CA, Hwang WYK, Iannone A, Ingelfinger F, Ivison SM, Jäck HM, Jani PK, Jávega B, Jonjic S, Kaiser T, Kalina T, Kamradt T, Kaufmann SHE, Keller B, Ketelaars SLC, Khalilnezhad A, Khan S, Kisielow J, Klenerman P, Knopf J, Koay HF, Kobow K, Kolls JK, Kong WT, Kopf M, Korn T, Kriegsmann K, Kristyanto H, Kroneis T, Krueger A, Kühne J, Kukat C, Kunkel D, Kunze-Schumacher H, Kurosaki T, Kurts C, Kvistborg P, Kwok I, Landry J, Lantz O, Lanuti P, LaRosa F, Lehuen A, LeibundGut-Landmann S, Leipold MD, Leung LYT, Levings MK, Lino AC, Liotta F, Litwin V, Liu Y, Ljunggren HG, Lohoff M, Lombardi G, Lopez L, López-Botet M, Lovett-Racke AE, Lubberts E, Luche H, Ludewig B, Lugli E, Lunemann S, Maecker HT, Maggi L, Maguire O, Mair F, Mair KH, Mantovani A, Manz RA, Marshall AJ, Martínez-Romero A, Martrus G, Marventano I, Maslinski W, Matarese G, Mattioli AV, Maueröder C, Mazzoni A, McCluskey J, McGrath M, McGuire HM, McInnes IB, Mei HE, Melchers F, Melzer S, Mielenz D, Miller SD, Mills KHG, Minderman H, Mjösberg J, Moore J, Moran B, Moretta L, Mosmann TR, Müller S, Multhoff G, Muñoz LE, Münz C, Nakayama T, Nasi M, Neumann K, Ng LG, Niedobitek A, Nourshargh S, Núñez G, O'Connor JE, Ochel A, Oja A, Ordonez D, Orfao A, Orlowski-Oliver E, Ouyang W, Oxenius A, Palankar R, Panse I, Pattanapanyasat K, Paulsen M, Pavlinic D, Penter L, Peterson P, Peth C, Petriz J, Piancone F, Pickl WF, Piconese S, Pinti M, Pockley AG, Podolska MJ, Poon Z, Pracht K, Prinz I, Pucillo CEM, Quataert SA, Quatrini L, Quinn KM, Radbruch H, Radstake TRDJ, Rahmig S, Rahn HP, Rajwa B, Ravichandran G, Raz Y, Rebhahn JA, Recktenwald D, Reimer D, Reis E Sousa C, Remmerswaal EBM, Richter L, Rico LG, Riddell A, Rieger AM, Robinson JP, Romagnani C, Rubartelli A, Ruland J, Saalmüller A, Saeys Y, Saito T, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sandrock I, Santoni A, Sanz RB, Saresella M, Sautes-Fridman C, Sawitzki B, Schadt L, Scheffold A, Scherer HU, Schiemann M, Schildberg FA, Schimisky E, Schlitzer A, Schlosser J, Schmid S, Schmitt S, Schober K, Schraivogel D, Schuh W, Schüler T, Schulte R, Schulz AR, Schulz SR, Scottá C, Scott-Algara D, Sester DP, Shankey TV, Silva-Santos B, Simon AK, Sitnik KM, Sozzani S, Speiser DE, Spidlen J, Stahlberg A, Stall AM, Stanley N, Stark R, Stehle C, Steinmetz T, Stockinger H, Takahama Y, Takeda K, Tan L, Tárnok A, Tiegs G, Toldi G, Tornack J, Traggiai E, Trebak M, Tree TIM, Trotter J, Trowsdale J, Tsoumakidou M, Ulrich H, Urbanczyk S, van de Veen W, van den Broek M, van der Pol E, Van Gassen S, Van Isterdael G, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Borstel A, von Volkmann K, Waisman A, Walker RV, Wallace PK, Wang SA, Wang XM, Ward MD, Ward-Hartstonge KA, Warnatz K, Warnes G, Warth S, Waskow C, Watson JV, Watzl C, Wegener L, Weisenburger T, Wiedemann A, Wienands J, Wilharm A, Wilkinson RJ, Willimsky G, Wing JB, Winkelmann R, Winkler TH, Wirz OF, Wong A, Wurst P, Yang JHM, Yang J, Yazdanbakhsh M, Yu L, Yue A, Zhang H, Zhao Y, Ziegler SM, Zielinski C, Zimmermann J, Zychlinsky A. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology 49 (2019), 10, Seiten 1457-1973. dx.doi.org/10.1002/eji.201970107
Costa-Marques L, Katrin K, Pardon M, Leovsky C, Swarbrick S, Fabian C, Stolzing A. Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model. Translational Neurodegeneration 8 (2019), 33, 11 Seiten. dx.doi.org/10.1186/s40035-019-0173-9
Czechowska K, Lannigan J, Wang L, Arcidiacono J, Ashhurst TM, Barnard RM, Bauer S, Bispo C, Bonilla DL, Brinkman RR, Cabanski M, Chang HD, Chakrabarti L, Chojnowski G, Cotleur B, Degheidy H, Dela Cruz GV, Eck S, Elliott J, Errington R, Filby A, Gagnon D, Gardner R, Green C, Gregory M, Groves CJ, Hall C, Hammes F, Hedrick M, Hoffman R, Icha J, Ivaska J, Jenner DC, Jones D, Kerckhof FM, Kukat C, Lanham D, Leavesley S, Lee M, Lin-Gibson S, Litwin V, Liu Y, Molloy J, Moore JS, Müller S, Nedbal J, Niesner R, Nitta N, Ohlsson-Wilhelm B, Paul NE, Perfetto S, Portat Z, Props R, Radtke S, Rayanki R, Rieger A, Rogers S, Rubbens P, Salomon R, Schiemann M, Sharpe J, Sonder SU, Stewart JJ, Sun Y, Ulrich H, Van Isterdael G, Vitaliti A, van Vreden C, Weber M, Zimmermann J, Vacca G, Wallace P, Tárnok A. Cyt-Geist: current and future challenges in Cytometry: reports of the CYTO 2018 conference workshops. Cytometry Part A 95 (2019), 6, Seite 598-644, dx.doi.org/10.1002/cyto.a.23777
de Vera J-P, Alawi M, Backhaus T, Baqué M, Billi D, Böttger U, Berger T, Cockell C, Demets R, Noetzel R d l T, Edwards H, Elsaesser A, Fagliarone C, Fiedler A, Foing B, Foucher F, Fritz J, Hanke F, Herzog T, Horneck G, Hübers H-W, Huwe B, Joshi J, Kozyrovska N, Kruchten M, Lasch P, Lee N, Leya T, Lorek A, Moritz S, Möller R, Olsson-Francis K, Onofri S, Ott S, Pacelli C, Podolich O, Martínez-Frías J, Rabbow E, Reitz G, Rettberg P, Reva O, Rothschild L, Sancho L G, Schulze-Makuch D, Selbmann L, Serrano P, Szewzyk U, Verseux C, Wagner D, Westall F, Wolter D, Zucconi L. Limits of life and the habitability of Mars: The ESA space experiment BIOMEX on the ISS. Astrobiology 19 (2019), 2, Seiten 145-157. dx.doi.org/10.1089/ast.2018.1897
Dluczek S, Tretbar US, Fricke S, Koehl U. CAR-T-Zellen: Update 2019. Transfusionsmedizin 9 (2019), 3, Seiten 187-200, dx.doi.org/10.1055/a-0833-2631
Dondapati SK, Lübberding H, Zemella A, Thoring L, Wüstenhagen DA, Kubick S. Functional reconstitution of membrane proteins derived from Eukaryotic Cell-Free Systems. Frontiers in Pharmacology (2019), 9 Seiten. dx.doi.org/10.3389/fphar
Dondapati SK, Pietruschka G, Thoring L, Wüstenhagen DA, Kubick S. Cell-free synthesis of human toll-like receptor 9 (TLR9): Optimization of synthesis conditions and functional analysis. PLoS One 14 (2019), 4, e0215897, 16 Seiten. dx.doi.org/10.1371/journal.pone.0215897
Fayad L, Oberbach A, Schweitzer M, Askin F, Voltaggio L, Larman T, Enderle M, Hahn H, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization (GMD): translation to a novel endoscopic metabolic therapy. Endoscopy International Open (2019), 07, 6 Seiten. dx.doi.org/10.1055/a-0957-3067
Fayad L, Schweitzer M, Raad M, Simsek C, Oleas R, Dunlap MK, Shah T, Doshi J, El Asmar M, Oberbach A, Singh VK, Steele K, Magnussen T, Kalloo AN, Khashab MA, Kumbhari V. A real-world, insurance-based algorithm using the two-fold running suture technique for transoral outlet reduction for weight regain and dumping syndrome after Roux-En-Y gastric bypass. Obesity Surgery 29 (2019), Seiten 2225-2232. dx.doi.org/10.1007/s11695-019-03828-1
Fayad L, Simsek C, Oleas R, Ichkhanian Y, Fayad GE, Ngamreungphong S, Schweitzer M, Oberbach A, Kalloo AN, Khashab MA, Kumbhari V. Safety and efficacy of endoscopically secured fully covered self-expandable metallic stents (FCSEMS) for post-bariatric complex Stenosis. Obesity Surgery 29 (2019), Seiten 3484-3492. dx.doi.org/10.1007/s11695-019-04021-0
Frimmel S, Hinz M, Schipper J, Bogdanow S, Mitzner S, Koball S. Cytokine adsorption is a promising tool in the therapy of hemophagocytic lymphohistiocytosis. International Journal of Artificial Organs 42 (2019), 11,
Seiten 658-664. dx.doi.org/10.1177/0391398819857444
Gialluisi A, Andlauer TFM, Mirza-Schreiber N, Moll K, Becker J, Hoffmann P, Ludwig KU, Czamara D, St Pourcain B, Brandler W, Honbolygó F, Tóth D, Csépe V, Huguet G, Morris AP, Hulslander J, Willcutt EG, DeFries JC, Olson RK, Smith SD, Pennington BF, Vaessen A, Maurer U, Lyytinen H, Peyrard-Janvid M, Leppänen PHT, Brandeis D, Bonte M, Stein JF, Talcott JB, Fauchereau F, Wilcke A, Francks C, Bourgeron T, Monaco AP, Ramus F, Landerl K, Kere J, Scerri TS, Paracchini S, Fisher SE, Schumacher J, Nöthen MM, Müller-Myhsok B, Schulte-Körne G. Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Translational psychiatry 9 (2019), 1, article no 77, 15 Seiten, dx.doi.org/10.1038/s41398-019-0402-0
Godino N, Pfisterer F, Gerling T, Guernth-Marschner C, Duschl C, Kirschbaum M. Combining dielectrophoresis and computer vision for precise and fully automated single-cell handling and analysis. Lab on a Chip 24 (2019), 19, Seiten 4016-4020. dx.doi.org/10.1039/c9lc00800d
Golde T, Glaser M, Tutmarc C, Elbalasy I, Huster C, Busteros G, Smith DM, Herrmann H, Käs JA, Schnauß J. The role of stickiness in the rheology of semiflexible polymers. Soft matter 15 8 (2019), Seite 4865-4872, dx.doi.org/10.1039/C9SM00433E
Haange SB, Jehmlich N, Hoffmann M, Weber K, Lehmann J, von Bergen M, Slanina U. Disease development is accompanied by changes in bacterial protein abundance and functions in a refined model of dextran sulfate sodium (DSS)-induced colitis. Journal of proteome research 18 (2019), 4, Seite 1774-1786, dx.doi.org/10.1021/acs.jproteome.8b00974
Haehnel S, Reiche K, Loeffler D, Horn A, Blumert C, Puppel SH, Kaiser N, Rapp F, Rade M, Horn F, Meixensberger J, Bechmann I, Gaunitz F, Winter K. Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research. Sci Rep. 2019 Dec 27;9(1):19961
Hartlage-Rübsamen M, Ratz V, Zeitschel U, Finzel L, Machner L, Köppen J, Schulze A, Demuth HU, von Hörsten S, Höfling C, Rossner S. Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, coaggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer’s disease. Acta Neuropathologica Communications, (2019) 7:79
Hays JP, Mitsakakis K, Luz S, Van Belkum A, Becker K, Van den Bruel A, Harbarth S, Rex JH, Simonsen GS, Di Gregori V, Lüdke G, Van Staa T, Moran-Gilad J, Bachmann TT, JPIAMR AMR-RDT consortium. The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex »mix-and-match« implementation package. European Journal of Clinical Microbiology & Infectious Diseases 38 (2019), Seiten 1015–1022. dx.doi.org/10.1007/s10096-019-03492-4
Hillmann A, Paebst F, Brehm W, Piehler D, Schubert S, Tárnok A, Burk J. A novel direct co-culture assay analyzed by multicolor flow cytometry reveals context- and cell type-specific immunomodulatory effects of equine mesenchymal stromal cells. PLoS one 14 (2019), 6, 21 Seiten, dx.doi.org/10.1371/journal.pone.0218949
Huber R, Kirsten H, Näkki A, Pohlers D, Thude H, Eidner T, Heinig M, Brand K, Ahnert P, Kinne RW. Association of human FOS promoter variants with the occurrence of knee-osteoarthritis in a case control association study. International journal of molecular sciences 20 (2019), 6, 13 Seiten, dx.doi.org/10.3390/ijms20061382
Kämpf C, Specht M, Scholz A, Puppel SH, Doose G, Reiche K, Schor J, Hackermüller J. uap: reproducible and robust HTS data analysis. BMC Bionformatics, 20 (2019), 664, 9 Seiten. dx.doi.org/10.1186/s12859-019-3219-1
Kern K, Havenith H, Delaroque N, Rautenberger P, Lehmann J, Fischer M, Spiegel H, Schillberg S, Ehrentreich-Foerster E, Aurich S, Treudler R, Szardenings M. The immunome of soy bean allergy: comprehensive identification and characterization of epitopes. Clinical & experimental allergy 49 (2019), 2, Seite 239-251, dx.doi.org/10.1111/cea.13285
Kielar C, Xin Y, Xu X, Zhu S, Gorin N, Grundmeier G, Möser C, Smith DM, Keller A. Effect of staple age on DNA origami nanostructure assembly and stability. Molecules 24 (2019), 14, 12 Seiten, dx.doi.org/10.3390/molecules24142577
Kloess S, Kretschmer A, Stahl L, Fricke S, Koehl U. CAR-Expressing Natural Killer Cells for Cancer Retargeting. Transfus Med Hemother. 2019 Feb;46(1):4-13. dx.doi.org/10.1159/000495771
Kloess S, Oberschmidt O, Dahlke J, Vu XK, Neudoerfl C, Kloos A, Gardlowski T, Matthies N, Heuser M, Meyer J, Sauer M, Falk C, Koehl U, Schambach A, Morgan MA. Preclinical Assessment of Suitable Natural Killer Cell Sources for Chimeric Antigen Receptor Natural Killer-Based »Off-the-Shelf« Acute Myeloid Leukemia Immunotherapies. Human Gene Therapy 30 (2019), 4, Seiten 381-401. dx.doi.org/10.1089/hum.2018.247
Küster E, Kalkhof S, Aulhorn S, von Bergen M, Gündel U. Effects of five substances with different modes of action on cathepsin H, C and L activities in zebrafish embryos. International journal of environmental research and public health 16 (2019), 20, 15 Seiten, dx.doi.org/10.3390/ijerph16203956
Lienau C, Gräwert T, Alves Avelar LA, Illarionov B, Held J, Knaab TC, Lungerich B, van Geelen L, Meier D, Geissler S, Cynis H, Riederer U, Buchholz M, Kalscheuer R, Bacher A, Mordmüller B, Fischer M, Kurz T. Novel reverse thia-analogs of fosmidomycin: synthesis and antiplasmodial activity. European journal of medicinal chemistry 181 (2019), Artikel 111555, 12 Seiten, dx.doi.org/10.1016/j.ejmech.2019.07.058
Lordick F, Platzbecker U, Büch E et al. Molekulare und zellbasierte Krebstherapie – Quo vadis? Onkologe (2019). dx.doi.org/10.1007/s00761-019-0612-3
Luehr M, Bauernschmitt N, Peterss S, Li Y, Heyn O, Dashkevich A, Oberbach A, Bagaev E, Pichlmaier MA, Juchem G, Hagl C. Incidence and surgical outcomes of patients with native and prosthetic aortic valve endocarditis. Annals of Thoracic Surgery (2019) pre-proof. dx.doi.org/10.1016/j.athoracsur.2019.10.029
Mahmoud M, Laufer S, Deigner HP. Visual aptamer-based capillary assay for ethanolamine using magnetic particles and strand displacement. Mikrochimica acta 186 (2019), 11, 8 Seiten, dx.doi.org/10.1007/s00604-019-3795-9
Mahmoud M, Laufer S, Deigner HP. Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument. Data in brief 24 (2019), 103946, 11 Seiten, dx.doi.org/10.1016/j.dib.2019.103946
Mahmoud M, Laufer S, Deigner HP. An aptamer based thermofluorimetric assay for ethanolamine. Biochimie 158 (2019), Seite 233-237, dx.doi.org/10.1016/j.biochi.2019.01.014
Oberbach A, Friedrich M, Lehmann S, Schlichting N, Kullnick Y, Gräber S, Buschmann T, Hagl C, Bagaev E; CardiOmics group; Clinical Microbiology group; Bioinformatics group. Bacterial infiltration in structural heart valve disease. The journal of thoracic and cardiovascular surgery (2019), [Epub ahead of print], dx.doi.org/10.1016/j.jtcvs.2019.02.019
Oberbach A, Schlichting N, Friedrich M, Lehmann S, Kullnick Y, Pichlmaier M, Hagl C, Bagaev E; CardiOmics group; Clinical Microbiology group; Clinical; Management group. Quantification of Multiple Bacteria in Calcified Structural Valvular Heart Disease. Semin Thorac Cardiovasc Surg. 2019 Oct 9. pii: S1043-0679(19)30319-3. dx.doi.org/10.1053/j.semtcvs.2019.10.003
Oberbach A, Schlichting N, Kullnick Y, Heinrich M, Lehmann S, Retschlag U, Friedrich M, Fayad L, Dietrich A, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization improves blood pressure, renin and cardiovascular lipid deposition in a rat model of obesity. Endoscopy International Open 07 (2019), 11 Seiten. dx.doi.org/10.1055/a-0990-9683
Oberschmidt O, Morgan M, Huppert V, Kessler J, Gardlowski T, Matthies N, Aleksandrova K, Arseniev L, Schambach A, Koehl U, Kloess S. Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering. Hum Gene Ther Methods. 2019 Jun;30(3):102-120. dx.doi.org/10.1089/hgtb.2019.039. Epub 2019 May 16
Procházková L, Leya T, Křížková H, Nedbalová L. Sanguina nivaloides and Sanguina aurantia gen. et spp. nov. (Chlorophyta): the taxonomy, phylogeny, biogeography and ecology of two newly recognised algae causing red and orange snow. FEMS Microbiol. Ecol. 95(6), (2019), fiz064
Rauwald HW, Liebold T, Grötzinger K, Lehmann J, Kuchta K. Labdanum and Labdanes of Cistus creticus and C. ladanifer: anti-Borrelia activity and its phytochemical profiling. Phytomedicine 60 (2019), article 152977, dx.doi.org/10.1016/j.phymed.2019.152977
Rockstroh A, Moges B, Berneck BS, Sattler T, Revilla-Fernández S, Schmoll F, Pacenti M, Sinigaglia A, Barzon L, Schmidt-Chanasit J, Nowotny N, Ulbert S. Specific detection and differentiation of tick-borne encephalitis and West Nile virus induced IgG antibodies in humans and horses. Transboundary and emerging diseases 66 (2019), 4, 8 Seiten, dx.doi.org/10.1111/tbed.13205
Ruppert C, Phogat N, Laufer S, Kohl M, Deigner HP. A smartphone readout system for gold nanoparticle-based lateral flow assays: application to monitoring of digoxigenin. Mikrochimica acta 186 (2019), 2,9 Seiten, dx.doi.org/10.1007/s00604-018-3195-6
Sandetskaya N, Isserstedt-John N, Koelsch A, Schattschneider S, Kuhlmeier D. An integrated homogeneous SPARCL™ immunoassay for rapid biomarker detection on a chip. Analytical methods 11 (2019), 19, Seite 2542-2550, dx.doi.org/10.1039/c9ay00198k
Sass S, Stöcklein WFM, Klevesath A, Hurpin J, Menger M, Hille C. Binding affinity data of DNA aptamers for therapeutic anthracyclines from microscale thermophoresis and surface plasmon resonance spectroscopy. Analyst. 144 (2019), 20, S. 6064-6073
Schüttler A, Altenburger R, Ammar M, Bader-Blukott M, Jakobs G, Knapp J, Krüger J, Reiche K, Wu GM, Busch W. Map and model-moving from observation to prediction in toxicogenomics. GigaScience 8 (2019), 6, 22 Seiten, dx.doi.org/10.1093/gigascience/giz057
Simsek C, Ichkhanian Y, Fayad L, Steele KE, Schweitzer MA, Lamond K, Vosoughi K, Doshi J, Shah T, Oberbach A, Al-Sabban A, Gandsas A, Kalloo AN, Khashab MA, Kumbhari V. Secured lumen-apposing fully covered metallic stents for Stenoses in post-bariatric surgery patients. Obesity Surgery 29 (2019), Seiten 2695-2699. dx.doi.org/10.1007/s11695-019-03906-4
Sinet-Mathiot V, Smith GM, Romandini M, Wilcke A, Peresani M, Hublin JJ, Welker F. Combining ZooMS and zooarchaeology to study Late Pleistocene hominin behaviour at Fumane (Italy). Scientific reports 9 (2019), 1, article 12350, 13 Seiten, dx.doi.org/10.1038/s41598-019-48706-z
Stahl L, Duenkel A, Hilger N, Tretbar US, Fricke S. The epitope-specific anti-human CD4 antibody MAX.16H5 and its role in immune tolerance. Frontiers in immunology 10 (2019), article 1035, 12 Seiten, dx.doi.org/10.3389/fimmu.2019.01035
Szendy M, Kalkhof S, Bittrich S, Kaiser F, Leberecht C, Labudde D, Noll M. Structural change in GadD2 of Listeria monocytogenes field isolates supports nisin resistance. International journal of food microbiology 305 (2019), article 108240, dx.doi.org/10.1016/j.ijfoodmicro.2019.108240
Thabet A, Schmäschke R, Fertey J, Bangoura B, Schönfelder J, Lendner M, Ulbert S, Daugschies A. Eimeria tenella oocysts attenuated by low energy electron irradiation (LEEI) induce protection against challenge infection in chickens. Veterinary parasitology 266 (2019), Seite 18-26, dx.doi.org/10.1016/j.vetpar.2019.01.001
Ueberham E, Spiegel H, Havenith H, Rautenberger P, Lidzba N, Schillberg S, Lehmann J. Simplified tracking of a soy allergen in processed food using a monoclonal antibody-based sandwich ELISA targeting the soybean 2S albumin gly m 8. Journal of agricultural and food chemistry 67 (2019), 31, Seite 8660-8667, dx.doi.org/10.1021/acs.jafc.9b02717
Ulbert S. West Nile virus vaccines – current situation and future directions. Human vaccines & immunotherapeutics 15 (2019), 10, Seite 2337-2342, dx.doi.org/10.1080/21645515.2019.1621149
Valainis D, Dondl P, Foehr P, Burgkart R, Kalkhof S, Duda GN, van Griensven M, Poh PSP. Integrated additive design and manufacturing approach for the bioengineering of bone scaffolds for favorable mechanical and biological properties. Biomedical Materials 14 (2019), 6, Articel 065002, 14 Seiten. dx.doi.org/10.1088/1748-605X/ab38c6
Wagner M, Hänsel R, Reinke S, Richter J, Altenbuchinger M, Braumann UD, Spang R, Löffler M, Klapper W. Automated macrophage counting in DLBCL tissue samples. Biological procedures online 21 (2019), article 13, 18 Seiten, dx.doi.org/10.1186/s12575-019-0098-9
Walcher L, Müller C, Hilger N, Kretschmer A, Stahl L, Wigge S, Rengelshausen J, Müller AM, Fricke S. Effect of combined sublethal X-ray irradiation ancyclosporine a treatment in NOD scid gamma (NSG) mice. Experimental animals 68 (2019), 1, Seite 1-11, dx.doi.org/10.1538/expanim.18-0056
Wichmann G, Gaede C, Melzer S, Bocsi J, Henger S, Engel C, Wirkner K, Wenning JR, Wald T, Freitag J, Willner M, Kolb M, Wiegand S, Löffler M, Dietz A, Tárnok A. Discrimination of head and neck squamous cell carcinoma patients and healthy adults by 10-color flow cytometry: development of a score based on leukocyte subsets. Cancers 11 (2019), 6, article 814, 18 Seiten, dx.doi.org/10.3390/cancers11060814
Wilmschen S, Schneider S, Peters F, Bayer L, Issmail L, Bánki Z, Grunwald T, von Laer D, Kimpel J. RSV vaccine based on rhabdoviral vector protects after single. Vaccines 7 (2019), 3, article 59, 17 Seiten, dx.doi.org/10.3390/vaccines7030059
Wittenbrink N, Herrmann S, Blazquez-Navarro A, Bauer Ch, Lindberg E, Reinke P, Sawitzki B, Thomusch O, Hugo Ch, Babel N, Seitz H, Or-Guil M. A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection. BMC Immunology 20 (2019), Articel 11, 10 Seiten. dx.doi.org/10.1186/s12865-019-0291-2
Yakoub-Agha I, Chabannon C, Bader P, Basak GW, Bonig H, Ciceri F, Corbacioglu S, Duarte RF, Einsele H, Hudecek M, Kersten MJ, Köhl U, Kuball J, Mielke S, Mohty M, Murray J, Nagler A, Robinson S, Saccardi R, Sanchez-Guijo F, Snowden JA, Srour M, Styczynski J, Urbano-Ispizua A, Hayden PJ, Kröger N. Management of adults and children undergoing CAR t-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE). Haematologica. 2019 Nov 21. pii: haematol.2019.229781. dx.doi.org/10.3324/haematol.2019.229781
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Publikationen 2018

Andersen JL, Fagerberg R, Flamm C, Kianian R, Merkle D, Stadler PF. Towards mechanistic prediction of mass spectra using graph transformation. Match 80 (2018), Nr.3, S. 705-731. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_705-731.pdf
Andersen JL, Flamm C, Merkle D, Stadler PF. Rule composition in graph transformation models of chemical reactions. Match 80 (2018), Nr.3, S. 661-704. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_661-704.pdf
Bahner N, Reich P, Frense D, Menger M, Schieke K, Beckmann D. An aptamer-based biosensor for detection of doxorubicin by electrochemical impedance spectroscopy. Analytical and Bioanalytical Chemistry 410 (2018), 5, S. 1453-1462. dx.doi.org/10.1007/s00216-017-0786-8
Baqué M, Hanke F, Böttger U, Leya T, Moeller R, Vera JP de. Protection of cyanobacterial carotenoids‘ Raman signatures by Martian mineral analogues after high-dose gamma irradiation. Journal of Raman Spectroscopy 49 (2018), 10, S. 1617-1627. dx.doi.org/10.1002/jrs.5449
Bayer L, Fertey J, Ulbert S, Grunwald T. Immunization with an adjuvanted low-energy electron irradiation inactivated respiratory syncytial virus vaccine shows immunoprotective activity in mice. Vaccine 36 (2018), 12, S. 1561-1569. dx.doi.org/10.1016/j.vaccine.2018.02.014
Bayer L, Gümpel J, Hause G, Müller M, Grunwald T. Non-human papillomaviruses for gene delivery in vitro and in vivo. PLoS one 13 (2018), Art. e0198996, 14 S. dx.doi.org/10.1371/journal.pone.0198996
Behm LVJ, Schlenther I, Petrausch M, Jorde F, Godino N, Pfisterer F, Duschl C, Kirschbaum M. A simple approach for the precise measurement of surface temperature distributions on the microscale under dry and liquid conditions based on thin Rhodamine B films. Sensors and Actuators B-Chemical 255 (2018), S. 2023-2031. dx.doi.org/10.1016/j.snb.2017.09.001
Bender P, Egger A, Westermann M, Taudte N, Sculeana A, Potempa J, Möller B, Buchholz M, Eick S. Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis – A pilot study. Archives of Oral Biology, 97 (2019),S. 223-230. dx.doi.org/10.1016/j.archoralbio.2018.10.022
Blaess M, Bibak N, Claus RA, Kohl M, Bonaterra GA, Kinscherf R, Laufer S, Deigner HP. NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation. European journal of medicinal chemistry 153 (2018), S. 73-104. dx.doi.org/10.1016/j.ejmech.2017.09.021
Blod C, Schlichting N, Schülin S, Suttkus A, Peukert N, Stingu CS, Hirsch C, Elger W, Lacher M, Bühligen U, Mayer S. The oral microbiome - the relevant reservoir for acute pediatric appendicitis? International journal of colorectal disease 33 (2018), Nr.2, S. 209-218. dx.doi.org/10.1007/s00384-017-2948-8
Boltze J, Ferrara F, Hainsworth AH, Bridges LR, Zille M, Lobsien D, Barthel H, McLeod DD, Gräßer F, Pietsch S, Schatzl AK, Dreyer AY, Nitzsche B. Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage. Journal of cerebral blood flow and metabolism Cereb Blood Flow Metab. 2018 (vorab online). dx.doi.org/10.1177/0271678X18802119
Canzler S, Stadler PF, Schor J. The fungal snoRNAome. RNA 24 (2018), 3, S. 342-360. dx.doi.org/10.1261/rna.062778.117
Donath A, Stadler PF. Split-inducing indels in phylogenomic analysis. Algorithms for molecular biology. Online journal 13 (2018), Art. 12, 12 S. / dx.doi.org/10.1186/s13015-018-0130-7
Dondapati SK, Wüstenhagen DA, Strauch E, Kubick S. Cell-free production of pore forming toxins: Functional analysis of thermostable direct hemolysin from Vibrio parahaemolyticus. Engineering in Life Sciences 18 (2018), 2, S. 140-148. dx.doi.org/10.1002/elsc.201600259
Dunkelmann T, Teichmann K, Ziehm T, Schemmert S, Frenzel D, Tusche M, Dammers C, Jürgens D, Langen KJ, Demuth HU, Shah NJ, Kutzsche J, Willuweit A, Willbold D. Aβ oligomer eliminating compounds interfere successfully with pEAβ(3–42) induced motor neurodegenerative phenotype in transgenic mice. Neuropeptides 67 (2018), S. 27-35. dx.doi.org/10.1016/j.npep.2017.11.011
Engel MC, Smith DM, Jobst MA, Sajfutdinow M, Liedl T, Romano F, Rovigatti L, Louis AA, Doye JPK. Force-induced unravelling of DNA origami. ACS nano 12 (2018), 7, S. 6734-6747. dx.doi.org/10.1021/acsnano.8b01844
Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V. Roquin targets mRNAs in a 3‘-UTR-specific manner by different modes of regulation. Nature Communications 9 (2018), Art. 3810. dx.doi.org/10.1038/s41467-018-06184-3
Fagerberg R, Flamm C, Kianian R, Merkle D, Stadler PF. Finding the K best synthesis plans. Journal of cheminformatics. Online journal 10 (2018), Art. 19, 21 S. dx.doi.org/10.1186/s13321-018-0273-z
Fingas F, Rückner A, Heenemann K, Volke D, Sieg M, Bielefeldt P, Grunwald T, Vahlenkamp TW, Hassert R, Hoffmann R. Highly sensitive ELISA for the serological detection of murine rotavirus EDIM based on its major immunogen VP6. Journal of Virological Methods 262 (2018), S. 72-78. dx.doi.org/10.1016/j.jviromet.2018.07.016
Fornefett J, Krause J, Klose K, Fingas F, Hassert R, Benga L, Grunwald T, Müller U, Schrödl W, Baums CG. Comparative analysis of humoral immune responses and pathologies of BALB/c and C57BL/6 wildtype mice experimentally infected with a highly virulent Rodentibacter pneumotropicus (Pasteurella pneumotropica) strain. BMC microbiology 18 (2018), Article 45, 11 S. dx.doi.org/10.1186/s12866-018-1186-8
Fornefett J, Krause J, Klose K, Fingas F, Hassert R, Eisenberg T, Schrödl W, Grunwald T, Müller U, Baums CG. Comparative analysis of clinics, pathologies and immune responses in BALB/c and C57BL/6 mice infected with Streptobacillus moniliformis. Microbes and infection 20 (2018), 2, S. 101-110. dx.doi.org/10.1016/j.micinf.2017.10.001
Fueldner C, Kohlschmidt J, Riemschneider S, Schulze F, Zoldan K, Esser C, Hauschildt S, Lehmann J. Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner. Toxicology 409 (2018), S. 80-90. dx.doi.org/10.1016/j.tox.2018.07.011
Geiß M, Anders J, Stadler PF, Wieseke N, Hellmuth M. Reconstructing gene trees from Fitch’s xenology relation. Journal of mathematical biology 77 (2018), Nr.5, S. 1459-1491. dx.doi.org/10.1007/s00285-018-1260-8
Golde T, Huster C, Glaser M, Händler T, Herrmann H, Käs JA, Schnauß J. Glassy dynamics in composite biopolymer networks. Soft matter 14 (2018), Nr.39, S. 7970-7978. dx.doi.org/10.1039/c8sm01061g
Greco R, Ciceri F, Noviello M, Bondanza A, Vago L, Oliveira G, Peccatori J, Cieri N, Ruggeri A, Koehl U, Fleischhauer K, Rocha V, Dazzi F, van der Werf SM, Eikema DJ, Terwel SR, Kuball J, Toubert A, Chabannon C, Bonini C; EBMT Cellular Therapy and Immunobiology Working Party (CTIWP). Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP. Bone Marrow Transplant. 53 (2018), S. 1201-1205. dx.doi.org/10.1038/s41409-018-0167-8.
Gröger V, Cynis H. Human endogenous retroviruses and their putative role in the development of autoimmune disorders such as Multiple Sclerosis. Frontiers in Microbiology 9 (2018), 265. dx.doi.org/10.3389/fmicb.2018.00265
Grünberg M, Quandt D, Cynis H, Demuth HU, Kindermann A, Magdolen V, Forssmann WG, Seliger B, Mägert HJ. Kallikrein-related peptidases are activators of the CC chemokine CCL14. European Journal of Immunology 48 (2018), 9, S. 1592-1594. dx.doi.org/10.1002/eji.201747452
Hartlage-Rübsamen M, Bluhm A, Piechotta A, Linnert M, Rahfeld JU, Demuth HU, Lues I, Kuhn PH, Lichtenthaler SF, Roßner S, Höfling C. Immunohistochemical evidence from APP-transgenic mice for glutaminyl cyclase as drug target to diminish pE-abeta formation. Molecules 23 (2018), 4, Art. 924, 17 S. dx.doi.org/10.3390/molecules23040924
Hilger N, Müller C, Stahl L, Müller AM, Zönnchen B, Dluczek S, Halbich C, Wickenhauser C, Gerloff D, Wurm AA, Behre G, Kretschmer A, Fricke, S. Incubation of Immune Cell Grafts With MAX.16H5 IgG1 Anti-Human CD4 Antibody Prolonged Survival After Hematopoietic Stem Cell Transplantation in a Mouse Model for Fms Like Tyrosine Kinase 3 Positive Acute Myeloid Leukemia. Frontiers in Immunology 9 (2018), 2408. dx.doi.org/10.3389/fimmu.2018.02408
Hoffmann A, Fallmann J, Vilardo E, Mörl M, Stadler PF, Amman F. Accurate mapping of tRNA reads. Bioinformatics 34 (2018), Nr.7, S. 1116-1124. dx.doi.org/10.1093/bioinformatics/btx756
Hoffmann M, Schwertassek U, Seydel A, Weber K, Falk W, Hauschildt S, Lehmann J. A refined and translationally relevant model of chronic DSS colitis in BALB/c mice. Laboratory Animals 53 (2018), 3, S. 240-252. dx.doi.org/10.1177/0023677217742681
Kaiser L, Weisser J, Kohl M, Deigner HP. Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection. Scientific Reports 8 (2018), Art: 5628. dx.doi.org/10.1038/s41598-018-23963-6
Kern K, Havenith H, Delaroque N, Rautenberger P, Lehmann J, Fischer M, Spiegel H, Schillberg S, Ehrentreich-Foerster E, Aurich S, Treudler R, Szardenings M. The immunome of soybean allergy: Comprehensive identification and characterization of epitopes. Clinical & experimental allergy 49 (2019), 2, S. 239-251. dx.doi.org/10.1111/cea.13285
Kersting, S, Rausch, V, Bier, FF, von Nickisch-Rosenegk, M. A recombinase polymerase amplification assay for the diagnosis of atypical pneumonia. Analytical Biochemistry 550 (2018),
S. 54-60. dx.doi.org/10.1016/j.ab.2018.04.014
Knigge X, Wenger C, Bier FF, Hölzel R. Dielectrophoretic immobilisation of nanoparticles as isolated singles in regular arrays. Journal of Physics D-Applied Physics 51 (2018), 6, 065308, 10 S. dx.doi.org/10.1088/1361-6463/aaa528
Koertge A, Wasserkort R, Wild T, Mitzner S. Extracorporeal Hemoperfusion as a Potential Therapeutic Option for Critical Accumulation of Rivaroxaban. Blood Purification 45 (2018), 126–128. dx.doi.org/10.1159/000484923
Köhl U, Arsenieva S, Holzinger A, Abken H. CAR T Cells in Trials: Recent Achievements and Challenges that Remain in the Production of Modified T Cells for Clinical Applications. Human gene therapy 29 (2018), 5, S. 559-568. dx.doi.org/10.1089/hum.2017.254
Königs C, Schultze-Strasser S, Quaiser A, Bochennek K, Schwabe D, Klingebiel TE, Koehl U, Cappel C, Rolle U, Bader P, Bremm M, Huenecke S, Bakhtiar S. An exponential regression model reveals the continuous development of B cell subpopulations used as reference values in children. Frontiers in Pediatrics 6 (2018), 121. dx.doi.org/10.3389/fped.2018.00121
Körtge A, Wild T, Heskamp B, Folk M, Mitzner S, Wasserkort R. Thrombogenicity and long-term cytokine removal capability of a novel asymmetric triacetate membrane hemofilter. Journal of artificial organs 21 (2018), 4, S. 435-442. dx.doi.org/10.1007/s10047-018-1062-1
Kuhlmann JD, Chebouti I, Kimmig R, Buderath P, Reuter M, Puppel SH, Wimberger P, Kasimir-Bauer S. Extracellular vesicle-associated miRNAs in ovarian cancer - design of an integrated NGS-based workflow for the identification of blood-based biomarkers for platinum-resistance. Clinical chemistry and laboratory medicine 13.11.2018. dx.doi.org/10.1515/cclm-2018-1048
Kuhn S, Splith K, Ballschuh C, Feldbrügge L, Krenzien F, Atanasov G, Benzing C, Hau HM, Engelmann C, Berg T, Schulte Am Esch J, Pratschke J, Robson SC, Schmelzle M. Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner. Purinergic Signalling 14 (2018), 4, S. 423-432. dx.doi.org/10.1007/s11302-018-9624-5
Lang A, Volkamer A, Behm L, Röblitz S, Ehrig R, Schneider M, Geris L, Wichard J, Buttgereit F. In silico methods - computational alternatives to animal testing. ALTEX 35 (2018), 1, S. 124-126. dx.doi.org/10.14573/altex.1712031
Laux EM, Ermilova E, Pannwitz D, Gibbons J, Hölzel R, Bier FF. Dielectric Spectroscopy of Biomolecules up to 110 GHz. Frequenz 72 (2018), 3-4, S. 135-140. dx.doi.org/10.1515/freq-2018-0010
Laux, EM, Bier, FF, Hölzel, R. Electrode-based AC electrokinetics of proteins: A mini-review. Bioelectrochemistry 120 (2018), S. 76-82. dx.doi.org/10.1016/j.bioelechem.2017.11.010
Liu Y, Schulze-Makuch D, Vera JP de, Cockell C, Leya T, Baqué M, Walther-Antonio M. The development of an effective bacterial single-cell lysis method suitable for whole genome amplification in microfluidic platforms. Micromachines 9 (2018), 8, art. no. 367, 17 S. dx.doi.org/10.3390/mi9080367
Lorenz JS, Schnauß J, Glaser M, Sajfutdinow M, Schuldt C, Käs JA, Smith DM. Synthetic transient crosslinks program the mechanics of soft, biopolymer-based materials. Advanced Materials 30 (2018), Art: 1706092, 8 S. dx.doi.org/10.1021/acs.jmedchem.8b00330
Madaboosi N, Uhlig K, Schmidt S, Vikulina AS, Möhwald H, Duschl C, Volodkin D. A »cell-friendly« window for the interaction of cells with hyaluronic acid/poly-l-lysine multilayers. Macromolecular Bioscience 18 (2018), 2, art. no. 1700319. dx.doi.org/10.1002/mabi.201700319
Moreira-Soto A, Cabral R, Pedroso C, Eschbach-Bludau M, Rockstroh A, Vargas LA, Postigo-Hidalgo I, Luz E, Sampaio GS, Drosten C, Netto EM, Jaenisch T, Ulbert S, Sarno M, Brites C, Drexler JF. Exhaustive TORCH Pathogen Diagnostics Corroborate Zika Virus Etiology of Congenital Malformations in Northeastern Brazil. mSphere. 3 (2018), 4, e00278-18. dx.doi.org/10.1128/mSphere.00278-18
Möser C, Lorenz JS, Sajfutdinow M, Smith DM. Pinpointed Stimulation of EphA2 Receptors via DNA-Templated Oligovalence. International Journal of Molecular Sciences (2018), Nr.19, 19 S. dx.doi.org/10.3390/ijms19113482
Müller B, Boltze J, Czepezauer I, Hesse V, LEGASCREEN Consortium, Wilcke A, Kirsten H. Dyslexia risk variant rs600753 is linked with dyslexia-specific differential allelic expression of DYX1C1. Genetics and molecular biology 41 (2018), Nr.1, S. 41-49. dx.doi.org/10.1590/1678-4685-gmb-2017-0165
Nøjgaard N, Geiß M, Merkle D, Stadler PF, Wieseke N, Hellmuth M. Time-consistent reconciliation maps and forbidden time travel. Algorithms for molecular biology. Online journal 13 (2018), Art. 2, 17 S. dx.doi.org/10.1186/s13015-018-0121-8
Oberbach A, Schlichting N, Heinrich M, Kullnick Y, Retschlag U, Lehmann S, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism in obese rats. Gastrointestinal endoscopy 87 (2018), Nr.1, S. 288-299. dx.doi.org/10.1016/j.gie.2017.04.038
Penna-Martinez M, Filmann N, Bogdanou D, Shoghi F, Huenecke S, Schubert R, Herrmann E, Koehl U, Husebye ES, Badenhoop K. High-dose vitamin D in Addison‘s disease regulates T-cells and monocytes: A pilot trial. Nutrition. 49 (2018), S. 66-73. dx.doi.org/10.1016/j.nut.2017.10.021.
Peters F, Westphal C, Kramer A, Westerman R. Is the rise in the prevalence of renal replacement therapy at older ages the price for living longer? Frontiers in Public Health 6 (2018), 138, 7 S. dx.doi.org/10.3389/fpubh.2018.00138
Pieroh P, Wagner DC, Alessandri B, Dabbagh Nazari M, Ehrlich A, Ghadban C, Hobusch C, Birkenmeier G, Dehghani F. Comparative examination of temporal glyoxalase 1 variations following perforant pathway transection, excitotoxicity, and controlled cortical impact injury. Neurotoxicity research 33 (2018), Nr.2, S. 412-421. dx.doi.org/10.1007/s12640-017-9808-8
Prohaska SJ, Berkemer SJ, Gärtner F, Gatter T, Retzlaff N, Students of the Graphs and Biological Networks Lab 2017, Höner Zu Siederdissen C, Stadler PF. Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem. Journal of mathematical biology 77 (2018), Nr.2, S. 313-341. dx.doi.org/10.1007/s00285-017-1197-3
Quaiser A, Köhl U. Was ist gesichert bei den Zelltherapien?: Möglichkeiten und Grenzen in der Immunonkologie. [What is established in cell therapies?: Possibilities and limits in immuno-oncology]. Internist (Berl). 59 (2018), 12, S. 1230-1238. dx.doi.org/10.1007/s00108-018-0516-0
Ramsbeck D, Hamann A, Richter G, Schlenzig D, Geissler S, Nykiel V, Cynis H, Schilling S, Buchholz M. Structure-guided design, synthesis and characterization of next-generation meprin β inhibitors. Journal of medicinal chemistry 61 (2018), 10, S. 4578-4592. dx.doi.org/10.1021/acs.jmedchem.8b00330
Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V. Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. Nature Communications 9 (2018), Art. 299, 15 S. dx.doi.org/10.1038/s41467-017-02582-1
Retzlaff N, Stadler PF. Phylogenetics beyond biology. Theory in Biosciences (2018), Online First, 11 S. dx.doi.org/10.1007/s12064-018-0264-7
Riemschneider S, Kohlschmidt J, Fueldner C, Esser C, Hauschildt S, Lehmann J. Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macrophages. Toxicology letters 296 (2018), S. 106-113. dx.doi.org/10.1016/j.toxlet.2018.07.050
Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut 67 (2018), 10, S. 1855-1863. dx.doi.org/10.1136/gutjnl-2017-314454
Rüppel N, Tröger V, Sandetskaya N, Kuhlmeier D, Schmieder S, Sonntag F. Detection and identification of staphylococcus aureus using magnetic particle enhanced surface plasmon spectroscopy. Engineering in life sciences 18 (2018), 4, S. 263-268. dx.doi.org/10.1002/elsc.201700098
Sajfutdinow M, Jacobs WM, Reinhardt A, Schneider C, Smith DM. Direct observation and rational design of nucleation behavior in addressable self-assembly. Proceedings of the National Academy of Sciences of the United States of America : PNAS 115 (2018), 26, S. E5877-E5886. dx.doi.org/10.1073/pnas.1806010115
Salzmann-Manrique E, Bremm M, Huenecke S, Stech M, Orth A, Eyrich M, Schulz A, Esser R, Klingebiel T, Bader P, Herrmann E, Koehl U. Joint Modeling of Immune Reconstitution Post Haploidentical Stem Cell Transplantation in Pediatric Patients With Acute Leukemia Comparing CD34+-Selected to CD3/CD19-Depleted Grafts in a Retrospective Multicenter Study. Frontiers in Immunology 9 (2018), 1841, 12 S. dx.doi.org/10.3389/fimmu.2018.01841
Sauer M, Haubner C, Richter G, Ehler J, Mencke T, Mitzner S, Margraf S, Altrichter J, Doß S, Nöldge-Schomburg G v. Impaired cell viability and functionality of hepatocytes after incubation with septic plasma-results of a second prospective biosensor study. Frontiers in Immunology. 9 (2018), 1448. dx.doi.org/10.3389/fimmu.2018.01448
Sauer M, Richter G, Altrichter J, Wild T, Doß F, Mencke T, Ehler J, Doß S, Koch S, Schubert A, Nöldge-Schomburg G, Mitzner SR. Effects of Bioreactor-Oxygenation During Extracorporeal Granulocytes Treatment in Septic Patients. Therapeutic apheresis and dialysis 22 (2018), 4, S. 389-398. dx.doi.org/10.1111/1744-9987.12657
Schäffler H, Breitrück A. Clostridium difficile - from colonization to infection. Frontiers in Microbiology 9 (2018), 646. dx.doi.org/10.3389/fmicb.2018.00646
Schilling S, Rahfeld JU, Lues I, Lemere CA. Passive Aβ immunotherapy: Current achievements and future perspectives. Molecules 23 (2018), 5, Art. 1068, 14 S. dx.doi.org/10.3390/molecules23051068
Schlenzig D, Cynis H, Hartlage-Ruebsamen M, Zeitschel U, Menge K, Fothe A, Ramsbeck D, Spahn C, Wermann M, Rossner S, Buchholz M, Schilling S, Demuth HU. Dipeptidyl-Peptidase activity of Meprin _ Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ formation. Journal of Alzheimer’s Disease 66 (2018) 359-375. dx.doi.org/10.3233/JAD-171183
Schneider T, Hahn-Löbmann S, Stephan A, Schulz S, Giritch A, Naumann M, Kleinschmidt M, Tusé D, Gleba Y. Plant-made Salmonella bacteriocins salmocins for control of Salmonella pathovars. Scientific Reports 8 (2018), Art: 4078. dx.doi.org/10.1038/s41598-018-22465-9
Schnotalle P, Koch K, Au-Yeung RKH, Reinke S, Winter K, Loeffler M, Braumann UD, Klapper W. T-Cell clustering in neoplastic follicles of follicular lymphoma. Cancer Microenvironment 11 (2018), 2-3, 135-140. dx.doi.org/10.1007/s12307-018-0217-1
Schultze-Florey RE, Tischer S, Kuhlmann L, Hundsdoerfer P, Koch A, Anagnostopoulos I, Ravens S, Goudeva L, Schultze-Florey C, Koenecke C, Blasczyk R, Koehl U, Heuft HG, Prinz I, Eiz-Vesper B, Maecker-Kolhoff B. Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease. Frontiers in Immunology. 9 (2018), 1475. dx.doi.org/10.3389/fimmu.2018.01475
Schulze A, Wermann M, Demuth HU, Yoshimoto T, Ramsbeck D, Schlenzig D, Schilling S. Continuous assays for meprin alpha and beta using prolyl tripeptidyl aminopeptidase (PtP) from Porphyromonas gingivalis. Analytical biochemistry 559 (2018), S. 11-16. dx.doi.org/10.1016/j.ab.2018.08.005
Stadler BMR,Stadler PF. Reachability, connectivity, and proximity in chemical spaces. Match 80 (2018), Nr.3, S. 639-659. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_639-659.pdf
Sustr D, Hlaváček A, Duschl C, Volodkin D. Multi-Fractional Analysis of Molecular Diffusion in Polymer Multilayers by FRAP: A New Simulation-Based Approach. Journal of Physical Chemistry B 122 (2018), 3, S. 1323-1333. dx.doi.org/10.1021/acs.jpcb.7b11051
Tan K, Jäger C, Schlenzig D, Schilling S, Buchholz M, Ramsbeck D. Tertiary-amine-based inhibitors of the astacin protease meprin α. ChemMedChem 13 (2018), 16, S. 1619-1624. dx.doi.org/10.1002/cmdc.201800300
Terekhov R, Selivanova I. Fractal aggregation of dihydroquercetin after lyophilization. Journal of Pharmaceutical Innovation (2018), S. 1-8. dx.doi.org/10.1007/s12247-018-9322-4
Thalheim T, Quaas M, Herberg M, Braumann UD, Kerner C, Loeffler M, Aust G, Galle J. Linking stem cell function and growth pattern of intestinal organoids. Developmental Biology 433 (2018), 2, S. 254-261. dx.doi.org/10.1016/j.ydbio.2017.10.013
Trento C, Bernardo ME, Nagler A, Kuçi S, Bornhäuser M, Köhl U, Strunk D, Galleu A, Sanchez-Guijo F, Gaipa G, Introna M, Bukauskas A, Le Blanc K, Apperley J, Roelofs H, Van Campenhout A, Beguin Y, Kuball J, Lazzari L, Avanzini MA, Fibbe W, Chabannon C, Bonini C, Dazzi F. Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers
Affiliated with the European Society for Blood and Marrow Transplantation. Biology of blood marrow transplantion 24 (2018), 11, S. 2365-2370. dx.doi.org/10.1016/j.bbmt.2018.07.015
Uhlig K, Wegener T, Hertle Y, Bookhold J, Jaeger M, Hellweg T, Fery A, Duschl C. Thermoresponsive Microgel Coatings as Versatile Functional Compounds for Novel Cell Manipulation Tools. Polymers 10 (2018), 6, Art: 656. dx.doi.org/10.3390/polym10060656
van Belkum A, Bachmann TT, Lüdke G, Lisby JG, Kahlmeter G, Mohess A, Becker K, Hays JP, Woodford N, Mitsakakis K, Moran-Gilad J, Vila J, Peter H, Rex JH, Dunne WM Jr;
JPIAMR AMR-RDT Working Group on Antimicrobial Resistance and Rapid Diagnostic Testing. Developmental roadmap for antimicrobial susceptibility testing systems. Nature Reviews Microbiology (2018), 12 S., article in press. dx.doi.org/10.1038/s41579-018-0098-9
Vikulina AS, Feoktistova NA, Balabushevich NG, Skirtach AG, Volodkin D. The mechanism of catalase loading into porous vaterite CaCO3 crystals by co-synthesis. Physical Chemistry Chemical Physics 20 (2018), 13, S. 8822-8831. dx.doi.org/10.1039/c7cp07836f
Vladimirov GK, Vikulina AS, Volodkin D, Vladimirov YA. Structure of the complex of cytochrome c with cardiolipin in non-polar environment. Chemistry and Physics of Lipids 214 (2018), S. 35-45. dx.doi.org/10.1016/j.chemphyslip.2018.05.007
Walcher L, Müller C, Hilger N, Kretschmer A, Stahl L, Wigge S, Rengelshausen J, Müller AM, Fricke S. Effect of combined sublethal X-ray irradiation and cyclosporine A treatment in NOD scid gamma (NSG) mice. Experimental animals (2018), Art. 18-0056, 26 S. dx.doi.org/10.1538/expanim.18-0056
Walter Costa MB, Höner Zu Siederdissen C, Tulpan D, Stadler PF, Nowick K. Temporal ordering of substitutions in RNA evolution: Uncovering the structural evolution of the Human Accelerated Region 1. Journal of theoretical biology 438 (2018), S. 143-150. dx.doi.org/10.1016/j.jtbi.2017.11.015
Wiegreffe D, Müller L, Steuck J, Zeckzer D, Stadler PF. The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments. BMC research notes. Online journal 11 (2018), Art. 512, 5 S. dx.doi.org/10.1186/s13104-018-3633-x
Wuchty S, Müller SA, Caufield JH, Häuser R, Aloy P, Kalkhof S, Uetz P. Proteome data improves protein function prediction in the interactome of Helicobacter pylori. Molecular & cellular proteomics 17 (2018), Nr.5, S. 961-973. dx.doi.org/10.1074/mcp.RA117.000474
Zemella A, Thoring L, Hoffmeister C, Šamalíková M, Ehren P, Wüstenhagen DA, Kubick S. Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin. Scientific Reports 8 (2018), 8514. dx.doi.org/10.1038/s41598-018-26936-x

Publikationen 2017

Agocs E, Kozma P, Nador J, Hamori A, Janosov M, Kalas B, Kurunczi S, Fodor B, Ehrentreich-Förster E, Fried M, Horvath R, Petrik P. Grating coupled optical waveguide interferometry combined with in situ spectroscopic ellipsometry to monitor surface processes in aqueous solutions. Applied surface science 421 (2017), Pt. B, S. 289-294. dx.doi.org/10.1016/j.apsusc.2016.07.166
Ahn J-S, Kim H-J, Kim YK, Lee S-S, Ahn SY, Jung SH, Yang DH, Lee JJ, Park HJ, Choi SH, Jung CW, Jang JH, Kim HJ, Moon JH, Sohn SK, Won JH, Kim SH, Szardenings M, Minden M, Hwan K, Dennis D. 5-Hydro-xymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia. OncoTarget. 8 (2017), 5, S. 8305-8314. dx.doi.org/10.18632/oncotarget.14171
Al Arab M, Bernt M, Höner Zu Siederdissen C, Tout K, Stadler PF. Partially local three-way alignments and the sequence signatures of mitochondrial genome rearrangements. Algorithms for molecular biology. 12 (2017), 22, 11 S. dx.doi.org/10.1186/s13015-017-0113-0
Al-Arab M, Höner zu Siederdissen C, Tout KR, Sahyoun AH, Stadler PF, Bernt M. Accurate annotation of protein-coding genes in mitochondrial genomes. Molecular phylogenetics and evolution 106 (2017), S. 209-216. dx.doi.org/10.1016/j.ympev.2016.09.024
Ambrosius B, Faissner S, Guse K, von Lehe M, Grunwald T, Gold R, Grewe B, Chan A. Teriflunomide and mono-methylfumarate target HIV-induced neuro-inflammation and neurotoxicity. Journal of neuroinflammation 14 (2017), Art. 51, 10 S. dx.doi.org/10.1186/s12974-017-0829-2
Andersen JL, Flamm C, Merkle D, Stadler PF. An intermediate level of abstraction for computational systems chemistry. Philosphical Transactions of the Royal Society A. 375 (2017), 2109, 20160354. dx.doi.org/10.1098/rsta.2016.0354
Antonyan A, Schlenzig D, Schilling S, Naumann M, Sharoyan S, Mardanyan S, Demuth HU. Concerted action of dipeptidyl peptidase IV and glutaminyl cyclase results in formation of pyro-glutamate-modified amyloid peptides in vitro. Neurochemistry International. 113 (2018), S. 112-119. dx.doi.org/10.1016/j.neuint.2017.12.001
Backofen R, Engelhardt J, Erxleben A, Fallmann J, Grüning B, Ohler U, Rajewsky N, Stadler PF. RNA-bioinformatics: Tools, services and databases for the analysis of RNA-based regulation. Journal of biotechnology. 261 (2017), S. 76-84. dx.doi.org/10.1016/j.jbiotec.2017.05.019
Bahner N, Reich P, Frense D, Menger M, Schieke K, Beckmann D. An aptamer-based biosensor for detection of doxorubicin by electro-chemical impedance spectroscopy. Analytical and Bioanalytical Chemistry. 410 (2018), 5, S. 1453-1462. dx.doi.org/10.1007/s00216-017-0786-8
Behm LVJ, Schlenther I, Petrausch M, Jorde F, Godino N, Pfisterer F, Duschl C, Kirschbaum M. A simple approach for the precise measurement of surface temperature distributions on the microscale under dry and liquid conditions based on thin Rhodamine B films. Sensors and Actuators B-Chemical. 255 (2018), 2, S. 2023–2031. dx.doi.org/10.1016/j.snb.2017.09.001
Berkemer SJ, Hoffmann A, Murray CRA, Stadler PF. SMORE: Synteny Modulator of Repetitive Elements. Life (Basel). 7 (2017), 4, 42, 16 S. dx.doi.org/10.3390/life7040042
Binder S, Hösler N, Riedel D, Zipfel I, Buschmann T, Kämpf C, Reiche K, Burger R, Gramatzki M, Hackermüller J, Stadler PF, Horn F. STAT3-induced long noncoding RNAs in multiple myeloma cells display different properties in cancer. Scientific Reports. 7 (2017), 11, Art. 7976, 13 S. dx.doi.org/10.1038/s41598-017-08348-5
Buschmann, T. DNABarcodes: An R package for the systematic construction of DNA sample tags. Bioinformatics 33 (2017), 6, S. 920-922. dx.doi.org/10.1093/bioinformatics/btw759
Connor D, Danckert L, Hoppe S, Bier FF, von Nickisch-Rosenegk M. Epitope determination of immunogenic proteins of Neisseria gonorrhoeae. PLoS One. 12 (2017), 7, Art. E0180962. dx.doi.org/10.1371/journal.pone.0180962
Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O‘Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European journal of immunology. 47 (2017), 10, S. 1584-1797. dx.doi.org/10.1002/eji.201646632
Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J. Recent progress in translational research on neurovascular and neurodegenerative disorders. Restorative neurology and neuroscience 35 (2017),1, S. 87-103. dx.doi.org/10.3233/RNN-160690
Diehl R, Ferrara F, Müller C, Dreyer AY, McLeod DD, Fricke S, Boltze J. Immunosuppression for in vivo research: State-of-the-art protocols and experimental approaches. Cellular and molecular immunology 14 (2017), 2, S. 146-179. dx.doi.org/10.1038/cmi.2016.39
Dondapati SK, Wüstenhagen DA, Strauch E, Kubick S. Cell-free production of pore forming toxins: Functional analysis of thermostable direct hemolysin from Vibrio parahaemolyticus. Engineering in Life Sciences. (2017), 9 S. dx.doi.org/10.1002/elsc.201600259
Doß S, Potschka H, Doß F, Mitzner S, Sauer M. Hepatotoxicity of antimycotics used for invasive fungal infections: In vitro results. BioMed research international 2017 (2017), Art. 9658018, 10 S. dx.doi.org/10.1155/2017/9658018
Dunkelmann T, Teichmann K, Ziehm T, Schemmert S, Frenzel D, Tusche M, Dammers C, Jürgens D, Langen KJ, Demuth HU, Shah NJ, Kutzsche J, Willuweit A, Willbold D. Aβ oligomer eliminating compounds interfere successfully with pEAβ (3–42) induced motor neurodegenerative phenotype in transgenic mice. Neuropeptides, Nov 2017. dx.doi.org/10.1016/j.npep.2017.11.011
Ewe A, Panchal O, Pinnapireddy SR, Bakowsky U, Przybylski S, Temme A, Aigner A. Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo. Nanomedicine. Nanotechnology, biology and medicine 13 (2017), 1, S. 209-218. dx.doi.org/10.1016/j.nano.2016.08.005
Fandrich A, Buller J, Memczak H, Stöcklein W, Hinrichs K, Wischerhoff E, Schulz B, Laschewsky A, Lisdat F. Responsive polymer-electrode interface-study of its thermo- and pH-sensitivity and the influence of peptide coupling. Electrochimica Acta 229 (2017), S. 325-333. dx.doi.org/10.1016/j.electacta.2017.01.080
Findeiß S, Etzel M, Will S, Mörl M, Stadler PF. Design of Artificial Riboswitches as Biosensors. Sensors (Basel). 17 (2017), 9, 1990, 28 S. dx.doi.org/10.3390/s17091990
Fischbach J, Loh Q, Bier FF, Lim TS, Frohme M, Glökler J. Alizarin Red S for online pyrophosphate detection identified by a rapid screening method. Scientific Reports. 7 (2017), Art. 45085, 9 S. dx.doi.org/10.1038/srep45085
Fornefett J, Krause J, Klose K, Fingas F, Hassert R, Eisenberg T, Schrödl W, Grunwald T, Müller U, Baums CG. Comparative analysis of clinics, pathologies and immune responses in BALB/c and C57BL/6 mice infected with Streptobacillus moniliformis. Microbes and infection. 20 (2018), 2, S. 101-110. dx.doi.org/10.1016/j.micinf.2017.10.001
Frimmel S, Mitzner SR, Koball S. Immunoadsorption as a Long-Term Therapy in Recurrent Focal Segmental Glomerulosclerosis After Renal Transplantation. Therapeutic apheresis and dialysis. 21 (2017), 1, S. 108-109. dx.doi.org/10.1111/1744-9987.12487
Gessner C, Ruschpler P, Fricke S, Gillissen A, Hoheisel G, Lehmann J, Sack U. Analyses of exhaled breath condensate cytokines for identification of lung cancer. Journal of laboratory medicine 41 (2017), 4, S. 187-194. dx.doi.org/10.1515/labmed-2017-0054
Grochowska KM, Yuanxiang P, Bär J, Raman R, Brugal G, Sahu G, Schweizer M, Bikbaev A, Schilling S, Demuth HU, Kreutz MR. Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO reports 18 (2017), 4, S. 511-657. dx.doi.org/10.15252/embr.201643519
Hahn MB, Meyer S, Schröter MA, Seitz H, Kunte HJ, Solomun T, Sturm H. Direct electron irradiation of DNA in fully aqueous environment. Damage determination in combination with Monte Carlo simulations. Physical chemistry chemical physics. 19 (2017), S. 1798-1805. dx.doi.org/10.1039/C6CP07707B
Hainsworth AH, Allan SM, Boltze J, Cunningham C, Farris C, Head E, Ihara M, Isaacs JD, Kalaria RN, Lesnik Oberstein SA, Moss MB, Nitzsche B, Rosenberg GA, Rutten JW, Salkovic-Petrisic M, Troen AM. Translational models for vascular cognitive impairment: A review including larger species. BMC medicine 15 (2017), Nr. 1, Art. 16, 12 S. dx.doi.org/10.1186/s12916-017-0793-9
Hamidouche Z, Rother K, Przybilla J, Krinner A, Clay D, Hopp L, Fabian C, Stolzing A, Binder H, Charbord P, Galle J. Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity. Stem cells 35 (2017), 3, S. 694-704. dx.doi.org/10.1002/stem.2514
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Hoffmann M, Schwertassek U, Seydel A, Weber K, Hauschildt S, Lehmann J. Therapeutic efficacy of a combined sage and bitter apple phytopharmaceutical in chronic DSS-induced colitis. Scientific Reports. 7 (2017), 1, Art. 14214, 10 S.dx.doi.org/10.1038/s41598-017-13985-x
Hoffmann T, Meyer A, Heiser U, Kurat S, Böhme L, Kleinschmidt M, Bühring KU, Hutter-Paier B, Farcher M, Demuth HU, Lues I, Schilling, S. Glutaminyl cyclase inhibitor PQ912 improves cognition in mouse models of Alzheimer‘s disease - studies on relation to effective target occupancy. The journal of pharmacology and experimental therapeutics 362 (2017), 1, S. 119-130. dx.doi.org/10.1124/jpet.117.240614
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Jaimes Y, Naaldijk Y, Wenk K, Leovsky C, Emmrich F. Mesenchymal Stem Cell-Derived Microvesicles Modulate Lipopolysaccharides-Induced Inflammatory Responses to Microglia Cells. Stem Cells. 35 (2017), 3, S. 812-823. dx.doi.org/10.1002/stem.2541
Johnson AA, Naaldijk Y, Hohaus C, Meisel HJ, Krystel I, Stolzing A. Protective effects of alpha phenyl-tert-butyl nitrone and ascorbic acid in human adipose derived mesenchymal stem cells from differently aged donors. Aging 9 (2017), 2, S. 340-352. dx.doi.org/10.18632/aging.101035
Jung SH, Lee HJ, Lee YK, Yang DH, Kim HJ, Rhee JH, Emmrich F, Lee JJ. A phase I clinical study of autologous dendritic cell therapy in patients with relapsed or refractory multiple myeloma. Oncotarget. 8 (2017), S. 41538-41548. dx.doi.org/10.18632/oncotarget.14582
Kehlen A, Haegele M, Böhme L, Cynis H, Hoffmann T, Demuth HU. N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity. Bioscience Reports, 37 (2017), 4, Art.BSR20170712, 14 S. dx.doi.org/10.1042/BSR20170712
Kim TH, Tyndel MS, Zhang Z, Ahn J, Choi S, Szardenings M, Lipton J, Kim HJ, Hwan DKD. Exome sequencing reveals DNMT3A and ASXL1 variants associate with progression of chronic myeloid leukemia after tyrosine kinase inhibitor therapy. Leukemia research 59 (2017), S. 142-148. dx.doi.org/10.1016/j.leukres.2017.06.009
Kolora SR, Faria R, Weigert A, Schaffer S, Grimm A, Henle K, Sahyoun AH, Stadler PF, Nowick K, Bleidorn C, Schlegel M. The complete mitochondrial genome of Lacerta bilineata and comparison with its closely related congener L. Viridis. Mitochondrial DNA 28 (2017), Nr. 1, S. 116-118. dx.doi.org/10.3109/19401736.2015.1111349
Kubitschke H, Schnauß J, Nnetu KD, Warmt E, Stange R, Käs JA. Actin and microtubule networks contribute differently to cell response for small and large strains. New Journal of Physics, 19 (2017, 093003. dx.doi.org/10.1088/1367-2630/aa7658
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Laux EM, Bier FF, Hölzel R. Electrode-based AC electrokinetics of proteins: A mini-review. Bioelectrochemistry. 120 (2018), S. 76-82. dx.doi.org/10.1016/j.bioelechem.2017.11.010
Lepik K, Annilo T, Kukuškina V; eQTLGen Consortium, Kisand K, Kutalik Z, Peterson P, Peterson H. C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis. PLoS Computional biology. 13 (2017), 9, Art. E1005766, 20 S. dx.doi.org/10.1371/journal.pcbi.1005766
Leven M, Knaab TC, Held J, Duffy S, Meister S, Fischli C, Meitzner D, Lehmann U, Lungerich B, Kuna K, Stahlke P, Delves MJ, Buchholz M, Winzeler EA, Avery VM, Mordmüller B, Wittlin S, Kurz T. 3-Hydroxy-N‘-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of Medicinal Chemistry, 60 (2017), 14, S. 6036-6044. dx.doi.org/10.1021/acs.jmedchem.7b00140
Lindner S, Gruhle K, Schmidt R, Garamus VM, Ramsbeck D, Hause G, Meister A, Sinz A, Drescher S. Azide-modified membrane lipids: Synthesis, properties, and reactivity. Langmuir, 33 (2017), 20, S. 4960-4973. dx.doi.org/10.1021/acs.langmuir.7b00228
Lukowski SW, Lloyd-Jones LR, Holloway A, Kirsten H, Hemani G, Yang J, Small K, Zhao J, Metspalu A, Dermitzakis ET, Gibson G, Spector TD, Thiery J, Scholz M, Montgomery GW, Esko T, Visscher PM, Powell JE. Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood. Nature Communications. 8 (2017), Art. 483, 10 S. dx.doi.org/10.1038/s41467-017-00473-z
Machné R, Murray DB, Stadler PF. Similarity-Based Segmentation of Multi-Dimensional Signals. Scientific Reports. 7 (2017), 12355, 11 S. dx.doi.org/10.1038/s41598-017-12401-8
Meinlschmidt P, Brode V, Sevenich R, Ueberham E, Schweiggert-Weisz U, Lehmann J, Rauh C, Knorr D, Eisner, P. High pressure processing assisted enzymatic hydrolysis - An innovative approach for the reduction of soy immunoreactivity. Innovative food science & emerging technologies 40 (2017), S. 58-67. dx.doi.org/10.1016/j.ifset.2016.06.022
Moreira-Soto A, Sarno M, Pedroso C, Netto EM, Rockstroh A, Luz E, Feldmann M, Fischer C, Bastos FA, Kümmerer BM, de Lamballerie X, Drosten C, Ulbert S, Brites C, Drexler JF. Evidence for congenital Zika virus infection from neutralizing antibody titers in maternal sera, Northeastern Brazil. The journal of infectious diseases. 216 (2017), 12, S. 1501-1504. dx.doi.org/10.1093/infdis/jix539
Müller B, Schaadt G, Boltze J, Emmrich F; LEGASCREEN Consortium, Skeide MA, Neef NE, Kraft I, Brauer J, Friederici AD, Kirsten H, Wilcke A. ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR. Brain Behavior. 7 (2017), 11, e00851. dx.doi.org/10.1002/brb3.851
Naaldijk Y, Jäger C, Fabian C, Leovsky C, Blüher A, Rudolph L, Hinze A, Stolzing A. Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice. Neuropathology and applied neurobiology 43 (2017), 4, S. 299-314. dx.doi.org/10.1111/nan.12319
Namasu CY, Katzerke C, Bräuer-Hartmann D, Wurm AA, Gerloff D, Hartmann JU, Schwind S, Müller-Tidow C, Hilger N, Fricke S, Christopeit M, Niederwieser D, Behre G. ABR, a novel inducer of transcription factor C/EBPα, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia. Oncotarget. 8 (2017), 61, S. 103626-103639. dx.doi.org/10.18632/oncotarget.22093
Neel NE, Müller B, Liebig J, Schaadt G, Grigutsch M, Gunter TC, Wilcke A, Kirsten H, Skeide MA, Kraft I, Kraus N, Emmrich F, Brauer J, Boltze J, Friederici AD. Dyslexia risk gene relates to representation of sound in the auditory brainstem. Developmental cognitive neuroscience 24 (2017), S. 63-71. dx.doi.org/10.1016/j.dcn.2017.01.008
Netto EM, Moreira-Soto A, Pedroso C, Höser C, Funk S, Kucharski AJ, Rockstroh A, Kümmerer BM, Sampaio GS, Luz E, Vaz SN, Dias JP, Bastos FA, Cabral R, Kistemann T, Ulbert S, de Lamballerie X, Jaenisch T, Brady OJ, Drosten C, Sarno M, Brites C, Drexler JF. High Zika Virus Seroprevalence in Salvador, Northeastern Brazil limits the potential for further outbreaks. MBio. 8 (2017), 6, Art. E01390-17. dx.doi.org/10.1128/mBio.01390-17
Nitzsche F, Müller C, Lukomska B, Jolkkonen J, Deten A, Boltze J. The MSC adhesion cascade - insights into homing and transendothelial migration. Stem Cells. 35 (2017), 6, S. 1446-1460. dx.doi.org/10.1002/stem.2614
Nowakowski A, Andrzejewska A, Boltze J, Nitzsche F, Cui LL, Jolkkonen J, Walczak P, Lukomska B, Janowski M. Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells. Scientific Reports 7 (2017), Art. 1103, 12 S. dx.doi.org/10.1038/s41598-017-01304-3
Oberbach A, Schlichting N, Feder S, Lehmann S, Kullnick Y, Buschmann T, Blumert C, Horn F, Neuhaus J, Neujahr R, Bagaev E, Hagl C, Pichlmaier M, Rodloff AC, Gräber S, Kirsch K, Sandri M, Kumbhari V, Behzadi A, Behzadi A, Correia JC, Mohr FW, Friedrich M. New insights into valve-related intramural and intracellular bacterial diversity in infective endocarditis. PLoS one. 12 (2017), 4, Art. e0175569, 20 S. dx.doi.org/10.1371/journal.pone.0175569
Oberbach A, Schlichting N, Heinrich M, Kullnick Y, Retschlag U, Lehmann S, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism in obese rats. Gastrointestinal endoscopy. 87 (2018), 1, S. 288-299.e6. dx.doi.org/10.1016/j.gie.2017.04.038
Oswald L, Grosser S, Smith DM, Kaes JA. Jamming transitions in cancer. Journal of Physics D: Applied Physics. 50 (2017), 48, Art. 483001. dx.doi.org/10.1088/1361-6463/aa8e83
Piechotta A, Parthier C, Kleinschmidt M, Gnoth K, Pillot T, Lues I, Demuth HU, Schilling S, Rahfeld JU, Stubbs M. Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy. Journal of biological chemistry. 292 (2017), S. 12713-12724. dx.doi.org/10.1074/jbc.M117.777839
Pott J, Burkhardt R, Beutner F, Horn K, Teren A, Kirsten H, Holdt LM, Schuler G, Teupser D, Loeffler M, Thiery J, Scholz M. Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery. Atherosclerosis. 259 (2017), S. 32-40. dx.doi.org/10.1016/j.atherosclerosis.2017.02.018
Prohaska SJ, Berkemer SJ, Gärtner F, Gatter T, Retzlaff N; Students of the Graphs and Biological Networks Lab 2017, Höner Zu Siederdissen C, Stadler PF. Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem. J Math Biol. 2017 Dec 19. http://dx.doi.org/10.1007/s00285-017-1197-3
Przybylski S, Gasch M, Marschner A, Ebert M, Ewe A, Helmig G, Hilger N, Fricke S, Rudzok S, Aigner A, Burkhardt J. Influence of nanoparticle-mediated transfection on proliferation of primary immune cells in vitro and in vivo. PLoS one. 12 (2017), 5, Art. e0176517, 16 S. dx.doi.org/10.1371/journal.pone.0176517
Ramsbeck D, Hamann A, Schlenzig D, Schilling S, Buchholz M. First insight into structure-activity relationships of selective Meprin ß inhibitors. Bioorganic & Medicinal Chemistry Letters. 27 (2017), 11, S. 2428-2431. dx.doi.org/10.1016/j.bmcl.2017.04.012
Rockstroh A, Moges B, Barzon L, Sinigaglia A, Palù G, Kumbukgolla W, Schmidt-Chanasit J, Sarno M, Brites C, Moreira-Soto A, Drexler JF, Ferreira OC, Ulbert S. Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop. Emerging microbes and infections. 6 (2017), Art. E99, 9 S. dx.doi.org/10.1038/emi.2017.87
Rodewohl A, Scholbach J, Leichsenring A, Köberle M, Lange F. Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. Innate immunity. 23 (2017), 3, S. 258-275. dx.doi.org/10.1177/1753425917690814
Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. (2017), gutjnl-2017-314454. dx.doi.org/10.1136/gutjnl-2017-314454
Sajfutdinow M, Uhlig K, Prager A, Schneider C, Abel B, Smith DM. Nanoscale patterning of self-assembled monolayer (SAM)-functionalised substrates with singlemolecule contact printing. Nanoscale. 39 (2017), 9, S. 15098-15106. dx.doi.org/10.1039/C7NR03696E
Sandetskaya N, Moos D, Pötter H, Seifert S, Jenerowicz M, Becker H, Zilch C, Kuhlmeier D. An integrated versatile lab-on-a-chip platform for the isolation and nucleic acid-based detection of pathogens. Future Science OA 3 (2017), 2, Art. FSO177, 13 S. dx.doi.org/10.4155/fsoa-2016-0088
Schnauß J, Glaser M, Lorenz JS, Schuldt C, Möser C, Sajfutdinow M, Haendler T, Kaes JA, Smith DM. DNA nanotubes as a versatile tool to study semiflexible polymers. Journal of Visualized Experiments JoVE. (2017), 128. dx.doi.org/10.3791/56056
Schneevoigt J, Fabian C, Leovsky C, Seeger J, Bahramsoltani M. In vitro expression of the extracellular matrix components aggrecan, collagen types I and II by articular cartilage-derived chondrocytes. Anatomia, histologia, embryologia 46 (2017), 1, S. 43-50. dx.doi.org/10.1111/ahe.12230
Schüttler A, Reiche K, Altenburger R, Busch W. The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis. Toxicological Sciences. 157 (2017), 2, S. 291-304. dx.doi.org/10.1093/toxsci/kfx045
Sonnabend A, Spahn V, Stech M, Zemella A, Stein C, Kubick S. Production of G protein-coupled receptors in an insect-based cell-free system. Biotechnology and bioengineering. 114 (2017), 10, S. 2328–2338. dx.doi.org/10.1002/bit.26346
Soria J, Acera A, Merayo-LLoves J, Durán JA, González N, Rodriguez S, Bistolas N, Schumacher S, Bier FF, Peter H, Stöcklein W, Suárez T. Tear proteome analysis in ocular surface diseases using label-free LC-MS/MS and multiplexed-microarray biomarker validation. Scientific Reports. 7 (2017), Art. 17478, 15 S. . http://dx.doi.org/10.1038/s41598-017-17536-2
Spahn C, Wermann M, Eichentopf R, Hause G, Schlenzig D, Schilling S. Purification of recombinant Aβ(1-42) and pGlu-Aβ(3-42) using preparative SDS-PAGE. Electrophoresis 38 (2017), 16, S. 2042-2049. dx.doi.org/10.1002/elps.201700154
Stamenković S, Dučić T, Stamenković V, Kranz A, Andjus PR. Imaging of glial cell morphology, SOD1 distribution and elemental composition in the brainstem and hippocampus of the ALS hSOD1G93A rat. Neuroscience 357 (2017), S. 37-55. dx.doi.org/10.1016/j.neuroscience.2017.05.041
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Stephan A, Hahn-Löbmann S, Rosche F, Buchholz M, Giritch A, Gleba Y. Simple purification of Nicotiana benthamiana-produced recombinant colicins: High-yield recovery of purified proteins with minimum alkaloid content supports the suitability of the host for manufacturing food additives. International Journal of Molecular Sciences. 19 (2017). 1, Art. 95, 13 S. dx.doi.org/10.3390/ijms19010095
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Thalheim T, Quaas M, Herberg M, Braumann UD, Kerner C, Loeffler M, Aust G, Galle J. Linking stem cell function and growth pattern of intestinal organoids. Developmental Biology. 433 (2018), 2, S. 254-261. dx.doi.org/10.1016/j.ydbio.2017.10.013
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Publikationen 2016

Bader D, Klier DT, Hettrich C, Bier FF, Wessig P. Detecting carbohydrate–lectin interactions using a fluorescent probe based on DBD dyes. Anal. Methods. 2016 Jan 13; 8, 1235-1238: DOI dx.doi.org/10.1039/C5AY02991K
Bavli D, Prill S, Ezra E, Levy G, Cohen M, Vinken M, Vanfleteren J, Jaeger M, Nahmias Y. Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction. Proceedings of the National Academy of Sciences of the United States of America : PNAS. 113 (2016), 16, S. E2231-E2240. dx.doi.org/10.1073/pnas.1522556113
Becker A, Eichentopf R, Sedlmeier R, Cynis H, Koch B, Stephan A, Bäuscher Ch, Kohlmann S, Hoffmann T, Kehlen A, Berg S, Freyse EJ, Osmand A, von Hörsten St, Graubner S, Demuth HU, Schilling S. IsoQC (QPCTL) knock out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes. Biological Chemistry. 397 (2016), 1, S. 45-55. dx.doi.org/10.1515/hsz-2015-0192
Boltze J, Wagner DC, Barthel H, Gounis M. Academic-industry collaborations in translational stroke research. Translational Stroke Research. 7 (2016), 4, S. 343-353. dx.doi.org/10.1007/s12975-016-0475-5
Boltze J, Ayata C. Challenges and controversies in translational stroke research : An introduction. Editorial. Translational Stroke Research. 7 (2016), 5, S. 355-357. dx.doi.org/10.1007/s12975-016-0492-4
Boltze J, Wagner DC, Henninger N, Plesnila N, Ayata C. Phase III preclinical trials in translational stroke research : community response on framework and guidelines. Translational Stroke Research. 7 (2016), 4, S. 241-247. dx.doi.org/10.1007/s12975-016-0474-6
Brameshuber M, Sevcsik E, Rossboth BK, Manner C, Deigner HP, Peksel B, Péter M, Török Z, Hermetter A, Schütz GJ. Oxidized phospholipids inhibit the formation of cholesterol-dependent plasma membrane nanoplatforms. Biophysical journal. 110 (2016), 1, S. 205-213. dx.doi.org/10.1016/j.bpj.2015.11.018
Canzler S, Stadler PF, Hertel J. U6 snRNA intron insertion occurred multiple times during fungi evolution. RNA biology. 13 (2016), 2, S. 119-127. dx.doi.org/10.1080/15476286.2015.1132139
Connor DO, Zantow J, Hust M, Bier FF, von Nickisch-Rosenegk M. Identification of novel immunogenic proteins of Neisseria gonorrhoeae by phage display. PLoS One. 11 (2016), Nr. 2, Art. e0148986, 24 S. dx.doi.org/10.1371/journal.pone.0148986
Corrales Ureña YR, Lisboa-Filho PN, Szardenings M, Gätjen L, Noeske, P LM, Rischka K. Formation and composition of adsorbates on hydrophobic carbon surfaces from aqueous laccase-maltodextrin mixture suspension. Applied surface science. 385 (2016), S. 216-224. dx.doi.org/10.1016/j.apsusc.2016.05.097
Couturier J-P, Wischerhoff E, Benin R, Hettrich C, Koetz J, Sütterlin M, Tiersch B, Laschewsky A. Thermoresponsive Polymers and Inverse Opal Hydrogels for the Detection of Diols. Langmuir. 32 (2016) 4333-4345: DOI dx.doi.org/10.1021/acs.langmuir.6b00803
Cui LL, Kinnunen T, Boltze J, Nystedt J, Jolkkonen J. Clumping and viability of bone marrow derived mesenchymal stromal cells under different preparation procedures : A flow cytometry-based in vitro study. Stem Cells International. (2016), Art. 1764938, 8 S. dx.doi.org/10.1155/2016/1764938
Cynis H, Frost JL, Crehan H, Lemere CA. Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges. Molecular neurodegeneration. 11 (2016), Art. 48, 11 S. dx.doi.org/10.1186/s13024-016-0115-2
Domin G, Findeiß S, Wachsmuth M, Will S, Stadler PF, Mörl M. Applicability of a computational design approach for synthetic riboswitches. Nucleic Acids Research, 2016 Dec 19, pii: gkw1267. (Epub ahead of print]. dx.doi.org/10.1093/nar/gkw1267
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Publikationen 2015

Barzon L, Pacenti M, Ulbert S, Palù G. Latest developments and challenges in the diagnosis of human West Nile virus infection. Expert review of anti-infective therapy. 13 (2015), 3, S. 327-42. DOI: dx.doi.org/10.1586/14787210.2015.1007044
Barzon L, Papa A, Lavezzo E, Franchin E, Pacenti M, Sinigaglia A, Masi G, Trevisan M, Squarzon L, Toppo S, Papadopoulou E, Nowotny N, Ulbert S, Piralla A, Rovida F, Baldanti F, Percivalle E, Palù G. Phylogenetic characterization of Central/Southern European lineage 2 West Nile virus: analysis of human outbreaks in Italy and Greece, 2013-2014. Clinical microbiology and infection. 21 (2015), 12, 1122.e1-1122.e10. DOI dx.doi.org/10.1016/j.cmi.2015.07.018
Bechlars S, Jäckel C, Diescher S, Wüstenhagen DA, Kubick S, Dieckmann R, Strauch E. Characterization of trh2 Harbouring Vibrio parahaemolyticus Strains Isolated in Germany. PLOS ONE | DOI: dx.doi.org/10.1371/journal.pone.0118559. Article
Betat H, Mede T, Tretbar S, Steiner L, Stadler PF, Mörl M, Prohaska SJ. The ancestor of modern Holozoa acquired the CCA-adding enzyme from Alphaproteobacteria by horizontal gene transfer. Nucleic acids research. 43 (2015), 14, 6739-46. DOI: dx.doi.org/10.1093/nar/gkv631
Boltze J, Arnold A, Walczak P, Jolkkonen J, Cui L, Wagner DC. The dark side of the force - constraints and complications of cell therapies for stroke. Frontiers in neurology. 6 (2015), 155. DOI dx.doi.org/10.3389/fneur.2015.00155
Bosserdt M, Erdőssy J, Lautner G, Witt J, Köhler K, Gajovic-Eichelmann N, Yarman A, Wittstock G, Scheller FW, Gyurcsányi RE. Microelectrospotting as a new method for electrosynthesis of surface-imprinted polymer microarrays for protein recognition. Biosensors and bioelectronics. 73 (2015), S.123-9. DOI dx.doi.org/10.1016/j.bios.2015.05.049
Brener O, Dunkelmann T, Gremer L, Van Groent T, Mirecka E, Kadishi I, Willuweit A, Kutzsche J, Jürgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J, Oesterhelft F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D. QIAD assay for quantitating a compound‘s efficacy in elimination of toxic Aβ oligomers. Scientific Reports. 5 (2015), 13222. DOI dx.doi.org/10.1038/srep13222
Brödel AK, Wüstenhagen DA, Kubick S. Cell-Free Protein Synthesis Systems Derived from Cultured Mammalian Cells. Methods Mol Biol. 2015;1261:129-40. doi: dx.doi.org/10.1007/978-1-4939-2230-7_7
Buga AM, Scheibe J, Moller K, Ciobanu O, Posel C, Boltze J, Popa-Wagner A. Granulocyte colony-stimulating factor and bone marrow mononuclear cells for stroke treatment in the aged brain. Current neurovascular research. 12 (2015), 2, S. 155-62. DOI dx.doi.org/10.2174/1567202612666150311112550
Burkhardt R, Kirsten H, Beutner F, Holdt LM, Gross A, Teren A, Tönjes A, Becker S, Krohn K, Kovacs P, Stumvoll M, Teupser D, Thiery J, Ceglarek U, Scholz M. Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood. PLoS Genetics. 11 (2015), 9:e1005510. DOI dx.doi.org/10.1371/journal.pgen.1005510
Couturier J-P, Sütterlin M, Laschewsky A, Hettrich C, Wischerhoff E. Inverse Opale aus responsiven Hydrogelen für die Detektion von Makromolekülen. Angew. Chem. 127 (2015) 6741-6745, DOI dx.doi.org/10.1002/ange.201500674
Couturier J-P, Sütterlin M, Laschewsky A, Hettrich C, Wischerhoff E. Responsive Inverse Opal Hydrogels for the Sensing of Macromolecules. Angew. Chem. Int. Ed. 54 (2015) 6641-6644, DOI dx.doi.org/10.1002/anie.201500674
Cui LL, Kerkelä E, Bakreen A, Nitzsche F, Andrzejewska A, Nowakowski A, Janowski M, Walczak P, Boltze J, Lukomska B, Jolkkonen J. The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity. Stem cell research and therapy. 6 (2015), 11. DOI dx.doi.org/10.1186/scrt544
Dammers C, Gremer L, Neudecker P, Demuth HU, Schwarten M, Willbold D. Purification and characterization of recombinant N-Terminally Pyroglutamate-modified Amyloid-β variants and structural analysis by solution NMR spectroscopy. PLoS One. 10 (2015), 10, e0139710. DOI: dx.doi.org/10.1371/journal.pone.0139710
Dammers C, Gremer L, Reiß K, Klein AN, Neudecker P, Hartmann R, Sun N, Demuth HU, Schwarten M, Willbold D. Structural analysis and aggregation propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol. PLoS One. 10 (2015), 11, e0143647. DOI dx.doi.org/10.1371/journal.pone.0143647
Ehler J, Koball S, Sauer M, Mitzner S, Hickstein H, Benecke R, Zettl UK. Response to Therapeutic Plasma Exchange as a Rescue Treatment in Clinically Isolated Syndromes and Acute Worsening of Multiple Sclerosis: A Retrospective Analysis of 90 Patients. Plos One 2015 Aug 5;10(8):e0134583. DOI dx.doi.org/10.1371/journal.pone.0134583. eCollection 2015
Eisold U, Sellrie F, Schenk JA, Lenz C, Stöcklein WFM, Kumke MU. Bright or dark immune complexes of anti-TAMRA antibodies for tailored fluorescence-based bioanalysis. Analytical and bioanalytical chemistry. 407 (2015), 12, S. 3313-23. DOI dx.doi.org/10.1007/s00216-015-8538-0
Engelhardt J, Stadler PF. Evolution of the unspliced transcriptome. BMC Evol Biol. 15 (2015), Aug 20, 166.
Fernández AF, Bayón GF, Urdinguio RG, Toraño EG, García MG, Carella A, Petrus-Reurer S, Ferrero C, Martinez-Camblor P, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Bueno C, Menéndez P, Mentink A, Mareschi K, Fabian C, Fagnani C, Medda E, Toccaceli V, Brescianini S, Moran S, Esteller M, Stolzing A, de Boer J, Nisticò L, Stazi MA, Fraga MF. H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells. Genome Research. 2015 Jan;25(1):27-40. DOI dx.doi.org/10.1101/gr.169011.113
Feoktistova N, Stoychev G, Puretskiy N, Ionov L, Volodkin D. Porous thermo-responsive pNIPAM microgels. European polymer journal. 68 (2015), S. 65-656. DOI dx.doi.org/10.1016/j.eurpolymj.2015.03.040
Fischer D, Angenvoort J, Ziegler U, Fast C, Maier K, Chabierski S, Eiden M, Ulbert S, Groschup MH, Lierz M. DNA vaccines encoding the envelope protein of West Nile virus lineages 1 or 2 administered intramuscularly, via electroporation and with recombinant virus protein induce partial protection in large falcons (Falco spp.). Vet Res. 2015 Aug 17;46(1):87. DOI dx.doi.org/10.1186/s13567-015-0220-1
Fjeld K, Weiss FU, Lasher D, Rosendahl J, Chen JM, Johansson BB, Kirsten H, Ruffert C, Masson E, Steine SJ, Bugert P, Cnop M, Grützmann R, Mayerle J, Mössner J, Ringdal M, Schulz HU, Sendler M, Simon P, Sztromwasser P, Torsvik J, Scholz M, Tjora E, Férec C, Witt H, Lerch MM, Njølstad PR, Johansson S, Molven A. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Nature genetics. 47 (2015), 5, S. 518-22. DOI dx.doi.org/10.1038/ng.3249
Gardner PP, Fasold M, Burge SW, Ninova M, Hertel J, Kehr S, Steeves TE, Griffiths-Jones S, Stadler PF. Conservation and losses of non-coding RNAs in avian genomes. PLoS One. 10 (2015), 3, e0121797. DOI dx.doi.org/10.1371/journal.pone.0121797
Gärtig C, Niemann K, Berthold J, Giel L, Leitschuh N, Boehm C, Roussak L, Vetter K, Kuhlmeier D. Development of a point-of-care-device for fast detection of periodontal pathogens. BMC Oral Health. 2015 Dec 24;15(1):165.
Georgi V, Georgi L, Blechert M, Bergmeister M, Zwanzig M, Wüstenhagen DA, Bier FF, Junga E, Kubick S. On-chip automation of cell-free protein synthesis: new opportunities due to a novel reaction mode. Lab Chip, 2015 Nov 11. [Epub ahead of print] DOI dx.doi.org/10.1039/C5LC00700C Article
Giri P, Ebert S, Braumann UD, Kremer M, Giri S, Machens HG, Bader A. Skin regeneration in deep second-degree scald injuries either by infusion pumping or topical application of recombinant human erythropoietin gel. Drug design, development and therapy. 9 (2015), S. 2565-2579. DOI dx.doi.org/10.2147/DDDT.S79425
Godino N, Jorde F, Lawlor D, Jaeger MS, Duschl C. Purification of microalgae from bacterial contamination using a disposable inertia-based microfluidic device. Journal of Micromechanics and Microengineering, 25 (2015), 8, 084002. DOI dx.doi.org/10.1088/0960-1317/25/8/084002
Grunwald T, Ulbert S. Improvement of DNA vaccination by adjuvants and sophisticated delivery devices: vaccine-platforms for the battle against infectious diseases. Clin Exp Vaccine Res. 2015 Jan;4(1):1-10. DOI dx.doi.org/10.7774/cevr.2015.4.1.1
Hahn M B, Solomun T, Wellhausen R, Herrmann S, Seitz H, Meyer S, Kunte H-J, Zeman J, Uhlig F, Smiatek J, Sturm H. The influence of the compatible solute ectoine on the local water structure: implications for the binding of the protein G5P to DNA. The Journal of Physical Chemistry, B, 119 (2015) 49, S. 15212–15220. DOI dx.doi.org/10.1021/acs.jpcb.5b09506
Haid S, Grethe C, Bankwitz D, Grunwald T, Pietschmann T. Identification of a human respiratory syncytial virus (hRSV) cell entry inhibitor by using a novel lentiviral pseudotype (hRSVpp) system. Journal of virology. 2015 Dec 30. [Epub ahead of print] DOI dx.doi.org/10.1128/JVI.03074-15
Hartlage-Rübsamen M, Waniek A, Meissner J, Morawski M, Schilling S, Jäger C, Kleinschmidt M, Cynis H, Kehlen A, Arendt T, Demuth HU, Rossner S. Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease. Acta Neuropathologica 2015; 129(4): 565-583. DOI dx.doi.org/10.1007/s00401-015-1395-2
Heathman TR, Stolzing A, Fabian C, Rafiq QA, Coopman K, Nienow AW, Kara B, Hewitt CJ. Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production. Cytotherapy. 17 (2015), 11, S. 1524-35. DOI dx.doi.org/10.1016/j.jcyt.2015.08.002
Hellmuth M, Wieseke N, Lechner M, Lenhof HP, Middendorf M, Stadler PF. Phylogenomics with paralogs. Proceedings of the National Academy of Sciences of the United States of America. 112 (2015), 7, 2058-63. DOI dx.doi.org/10.1073/pnas.1412770112
Hertel J, Stadler PF. The expansion of animal MicroRNA families revisited. Life (Basel). 5 (2015), 1, 905-20. DOI dx.doi.org/10.3390/life5010905
Hoffmann S, Stadler PF, Strimmer K. A simple data-adaptive probabilistic variant calling model. Algorithms for molecular biology. 10 ( 2015), 10. DOI dx.doi.org/10.1186/s13015-015-0037-5
Höner Zu Siederdissen C, Hofacker IL, Stadler PF. Product Grammars for Alignment and Folding. IEEE/ACM Trans Comput Biol Bioinform. 12 (2015), 3, 507-19.
Hüttl C, Hettrich C, Riedel M, Henklein P, Rawel H, Bier FF. Development of peptidyl lysine dendrons: 1,3-Dipolar cycloaddition for peptide coupling and antibody recognition. Chemical biology and drug design. 85 (2015), 5, S. 565-573. DOI dx.doi.org/10.1111/cbdd.12444
Janowski M, Wagner DC, Boltze J. Stem cell-based tissue replacement after stroke: factual necessity or notorious fiction? Stroke. 46 (2015), 8, S. 2354-63. DOI dx.doi.org/10.1161/STROKEAHA.114.007803
Jeenduang N, Porntadavity S, von Nickisch-Rosenegk M, Bier FF, Promptmas C. Two-dye based arrayed primer extension for simultaneous multigene detection in lipid metabolism. Clinica chimica acta. 442 (2015), S. 36-43. DOI dx.doi.org/10.1016/j.cca.2015.01.005
Jetzschmann KJ, Jágerszki G, Dechtrirat D, Yarman A, Gajovic-Eichelmann N, Gilsing HD, Schulz B, Gyurcsányi RE, Scheller FW. Vectorially imprinted hybrid nanofilm for Acetylcholinesterase recognition. Advanced functional materials. 25 (2015), 32, S. 5178-5183. DOI dx.doi.org/10.1002/adfm.201501900
Kee NLA, Krause J, Blatch GL, Muramoto K, Sakka K, Sakka M, Naudé RJ, Wagner L, Wolf R, Rahfeld JU, Demuth HU, Mielicki WP, Frost CL. The proteolytic profile of human cancer procoagulant suggests that it promotes cancer metastasis at the level of activation rather than degradation. Protein Journal. 34 (2015), 5, S. 338-48. DOI dx.doi.org/10.1007/s10930-015-9628-8
Kim H, Won SJ, Fabian C, Kang M, Szardenings M, Shin M. Mitochondrial DNA aberrations and pathophysiological implications in hematopoietic diseases, chronic inflammatory diseases, and cancers. Annals of Laboratory Medicine. 2015 Jan;35(1):1-14. DOI dx.doi.org/10.3343/alm.2015.35.1.1
Kim JE, Phan TX, Nguyen VH, Dinh-Vu HV, Zheng JH, Yun M, Park SG, Hong Y, Choy HE, Szardenings M, Hwang W, Park JA,Park S, Im SH, Min JJ. Salmonella typhimurium suppresses tumor growth via the pro-inflammatory Cytokine Interleukin-1β. Theranostics. 5 (2015), 12, S. 1328-42. DOI dx.doi.org/10.7150/thno.11432
Kirsten H, Al-Hasani H, Holdt L, Gross A, Beutner F, Krohn K, Horn K, Ahnert P, Burkhardt R, Reiche K, Hackermüller J, Löffler M, Teupser D, Thiery J, Scholz M. Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci. Hum Mol Genet. 2015 May 27.
Kleinschmidt M, Schoenfeld R, Göttlich C, Bittner D, Metzner JE, Leplow B, Demuth HU. Characterizing aging, mild cognitive Impairment, and Dementia with blood-based biomarkers and neuropsychology. Journal of Alzheimer‘s Disease. 50 (2015), 1, S. 111-26. DOI dx.doi.org/10.3233/JAD-143189
Köberle M, Müller K, Kamprad M, Horn F, Scholz M. Monitoring disease progression and therapeutic response in a disseminated tumor model for Non-Hodgkin Lymphoma by bioluminescence imaging. Molecular Imaging. 14 (2015), 400-13.
Kraft I, Cafiero R, Schaadt G, Brauer J, Neef NE, Müller B, Kirsten H, Wilcke A, Boltze J, Friederici AD, Skeide MA. Cortical differences in preliterate children at familiar risk of dyslexia are similar to those observed in dyslexic readers. Brain. 138 (2015), (Pt 9):e378. DOI dx.doi.org/10.1093/brain/awv036
Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Bergmann AK, Betts MJ, Carrillo-de-Santa-Pau E, Doose G, Gutwein J, Richter J, Hovestadt V, Huang B, Rico D, Jühling F, Kolarova J, Lu Q, Otto C, Wagener R, Arnolds J, Burkhardt B, Claviez A, Drexler HG, Eberth S, Eils R, Flicek P, Haas S, Hummel M, Karsch D, Kerstens HH, Klapper W, Kreuz M, Lawerenz C, Lenze D, Loeffler M, López C, MacLeod RA, Martens JH, Kulis M, Martín-Subero JI, Möller P, Nagel I, Picelli S, Vater I, Rohde M, Rosenstiel P, Rosolowski M, Russell RB, Schilhabel M, Schlesner M, Stadler PF, Szczepanowski M, Trümper L, Stunnenberg HG; ICGC MMML-Seq project; BLUEPRINT project, Küppers R, Ammerpohl O, Lichter P, Siebert R, Hoffmann S, Radlwimmer B. DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control. Nature Genetics. 47 (2015), 11, 1316-25. DOI dx.doi.org/10.1038/ng.3413
Laubichler MD, Stadler PF, Prohaska SJ, Nowick K. The relativity of biological function. Theory Biosciences. 134 (2015), 3-4, 143-7. DOI dx.doi.org/10.1007/s12064-015-0215-5
Lauster D, Pawolski D, Storm J, Ludwig K, Volkmer R, Memczak H, Herrmann A, Bhatia S. Potential of acylated peptides to target the influenza A virus. Beilstein journal of organic chemistry. 11 (2015), S. 589-595. DOI dx.doi.org/10.3762/bjoc.11.65
Laux EM, Knigge X, Bier FF, Wenger C, Hölzel R. Dielectrophoretic immobilization of proteins: Quantification by atomic force microscopy. Electrophoresis. 36 (2015), 17, S. 2094-2101. DOI dx.doi.org/10.1002/elps.201500108
Lehmann J, Schulz RM, Sanzenbacher R. Strategische Betrachtungen zur Konzeption und Wahl von Tiermodellen bei nicht-klinischen Prüfungen von zellbasierten Therapeutika. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2015 Oct 2. [Epub ahead of print] DOI dx.doi.org/10.1007/s00103-015-2239-x
Leovsky C, Fabian C, Naaldijk Y, Jäger C, Jang HJ, Böhme J, Rudolph L, Stolzing A. Biodistribution of in vitro-derived microglia applied intranasally and intravenously to mice: effects of aging. Cytotherapy. 17 (2015), 11, S. 1617-26. DOI dx.doi.org/10.1016/j.jcyt.2015.07.019
Li S, Sun X, Bai YM, Qin HM, Wu XM, Zhang X, Jolkkonen J, Boltze J, Wang SP. Infarction of the corpus callosum: a retrospective clinical investigation. PLoS One. 10 (2015), 3, e0120409. DOI dx.doi.org/10.1371/journal.pone.0120409
Lim JS, Nguyen KC, Han JM, Jang IS, Fabian C, Cho KA. Direct regulation of TLR5 expression by Caveolin-1. Molecules and cells. 38 (2015), 12, S. 1111-7. DOI dx.doi.org/10.14348/molcells.2015.0213
Lim JS, Nguyen KC, Nguyen CT, Jang IS, Han JM, Fabian C, Lee SE, Rhee JH, Cho KA. Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence. Aging Cell. 14 (2015), 5, S. 907-15. DOI dx.doi.org/10.1111/acel.12383
Liu B, Rahfeld JU, Kleinschmidt M, O‘Nuallain B, Le K, Lues I, Caldarone BJ, Schilling S, Demuth HU, Lemere CA. An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice. Neubiology of Aging. 36 (2015), 12, S. 3187–3199. DOI dx.doi.org/10.1016/j.neurobiolaging.2015.08.021
Liu X, Hinney A, Scholz M, Scherag A, Tönjes A, Stumvoll M, Stadler PF, Hebebrand J, Böttcher Y. Indications for potential parent-of-origin effects within the FTO gene. PLoS One. 10 (2015), 3, e0119206. DOI dx.doi.org/10.1371/journal.pone.0119206
Männel C, Meyer L, Wilcke A, Boltze J, Kirsten H, Friederici AD. Working-memory endophenotype and dyslexia-associated genetic variant predict dyslexia phenotype. Cortex. 71 (2015), S. 291-305. DOI dx.doi.org/10.1016/j.cortex.2015.06.029
Maruschke M, Riebold D, Holtfreter MC, Sombetzki M, Mitzner S, Loebermann M, Reisinger EC, Hakenberg OW. Pneumocystis pneumonia (PCP) and Pneumocystis jirovecii carriage in renal transplantation patients: a single-centre experience. Wien Klin Wochenschr. 2014 Dec;126(23-24):762-6.
Möller K, Pösel C, Kranz A, Schulz I, Scheibe J, Didwischus N, Boltze J, Weise G, Wagner DC. Arterial hypertension aggravates innate immune responses after experimental stroke. Frontiers in cellular neuroscience. 9 (2015), 461. DOI dx.doi.org/10.3389/fncel.2015.00461
Morschheuser L, Mükusch S, Riedner M, Seitz H, Rohn S. High-performance thin-layer chromatography as a fast screening tool for phosphorylated peptides. Journal of Chromatography B. 1008 (2016), S. 198-205. DOI dx.doi.org/10.1016/j.jchromb.2015.11.055
Müller S, Schubert A, Zajac J, Dyck T, Oelkrug C. IgY anti-bodies in human nutrition for disease prevention. Nutrition Journal. 14 (20159, 109. DOI dx.doi.org/10.1186/s12937-015-0067-3
Naaldijk Y, Johnson AA, Ishak S, Meisel HJ, Hohaus C, Stolzing A. Migrational changes of mesenchymal stem cells in response to cytokines, growth factors, hypoxia, and aging. Experimental cell research. 338 (2015), 1, S. 97-104. DOI dx.doi.org/10.1016/j.yexcr.2015.08.019
Nitsche A, Rose D, Fasold M, Reiche K, Stadler PF. Comparison of splice sites reveals that long noncoding RNAs are evolutionarily well conserved. RNA. 2015 May;21(5):801-12.
Nitzsche B, Frey S, Collins LD, Seeger J, Lobsien D, Dreyer A, Kirsten H, Stoffel MH, Fonov VS, Boltze J. A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes. Front in neuroanatomy. 9 (2015), 69. DOI dx.doi.org/10.3389/fnana.2015.00069
Oelkrug C, Hartke M, Schubert A. Mode of action of anticancer peptides (ACPs) from amphibian origin. Anticancer research. 35 (2015), 2, S. 635-43.
Oelkrug C, Horn K, Makert GR, Schubert A. Novel in vitro platform to investigate myotube atrophy. Anticancer research. 35 (2015), 4, S. 2085-91.
Oelkrug C, Sack U, Boldt A, Nascimento IC, Ulrich H, Fricke S. Antibody- and aptamer-strategies for GvHD prevention. Journal of Cellular and Molecular Medicine. 2015 Jan;19(1):11-20. DOI: dx.doi.org/10.1111/jcmm.12416
Prill S, Bavli D, Levy G, Ezra E, Schmälzlin E, Jaeger MS, Schwarz M, Duschl C, Cohen M, Nahmias Y. Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone. Archive of toxicology. 2015 Jun 4. [Epub ahead of print] DOI dx.doi.org/10.1007/s00204-015-1537-2
Prokopovic V, Duschl C, Volodkin D. Hyaluronic Acid/Poly-l-Lysine Multilayers as Reservoirs for Storage and Release of Small Charged Molecules. Macromolecular Bioscience. 15 (2015), 10, S. 1357-1363. DOI dx.doi.org/10.1002/mabi.201500093
Quast RB, Mrusek D, Hoffmeister C, Sonnabend A, Kubick S. Cotranslational incorporation of non-standard amino acids using cell-free protein synthesis. FEBS Lett. 2015 Jul 8;589(15):1703-12. doi: dx.doi.org/10.1016/j.febslet.2015.04.041. Epub 2015 May 1. Article
Quast RB, Kortt O, Henkel J, Srujan KD, Wüstenhagen DA, Stech M, Kubick S. Automated production of functional membrane proteins usingeukaryotic cell-free translation systems. Journal of Biotechnology 203 (2015) 45–53. Article
Rizzoli A, Jimenez-Clavero MA, Barzon L, Cordioli P, Figuerola J, Koraka P, Martina B, Moreno A, Nowotny N, Pardigon N, Sanders N, Ulbert S, Tenorio A. The challenge of West Nile virus in Europe: knowledge gaps and research priorities. Eurosurveillance. 20 (2015), 20, 5. DOI dx.doi.org/10.2807/1560-7917.ES2015.20.20.21135
Riemschneider S, Herzberg M, Lehmann J. Subtoxic Doses of Cadmium Modulate Inflammatory Properties of Murine RAW 264.7 Macrophages. Biomed Res Int. 2015;2015:295303. DOI: dx.doi.org/10.1155/2015/295303
Rockstroh A, Barzon L, Pacenti M, Palù G, Niedrig M, Ulbert S. Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections. PLoS neglected tropical diseases. 9 (2015), 11 :e0004218. DOI http://dx.doi.org/10.1371/journal.pntd.0004218
Sahyoun AH, Hölzer M, Jühling F, Höner zu Siederdissen C, Al-Arab M, Tout K, Marz M, Middendorf M, Stadler PF, Bernt M. Towards a comprehensive picture of alloacceptor tRNA remolding in metazoan mitochondrial genomes. Nucleic acids research. 43 (2015), 16, 8044-56. DOI dx.doi.org/10.1093/nar/gkv746
Sandetskaya N, Engelmann B, Brandenburg K, Kuhlmeier D. Application of immobilized synthetic anti-lipopolysaccharide peptides for the isolation and detection of bacteria. Eur J Clin Microbiol Infect Dis. 2015 May 19.
Schlenzig D, Wermann M, Ramsbeck D, Moenke-Wedler T, Schilling S. Expression, purification and initial characterization of human meprin β from Pichia pastoris. Protein expression and purification. 116 (2015), S. 75-81. DOI dx.doi.org/10.1016/j.pep.2015.08.001
Schmiedeknecht G. Challenges of Manufacturing of ATMP’s for clinical trials. 2015 PDA Europe Conference Advanced Therapy Medicinal Products, Amsterdam, Netherlands, June 2–3, 2015.
Schmidt F, Hilger N, Oelkrug C, Svanidze E, Ruschpler P, Eichler W, Boldt A, Emmrich F, Fricke S. Flow cytometric analysis of the graft-versus-Leukemia-effect after hematopoietic stem cell transplantation in mice. Cytometry A. 87 (2015), 4, S. 334-45. DOI dx.doi.org/10.1002/cyto.a.22619
Schumacher S, Muekusch S, Seitz H. Up-to-date applications of microarrays and their way to commercialization. Microarrays. 4 (2015), 2, S. 196-213. DOI dx.doi.org/10.3390/microarrays4020196
Schumacher S, Seitz H. Multiplex approach for an immunological detection of drugbase: a validation study. Toxichem Krimtech. 39 (2015), 82, S. 151-154.
Seifert F, Demuth HU, Weichler T, Ludwig HH, Tittmann K, Schilling S. Phosphate ions and glutaminyl cyclases catalyze the cyclization of glutaminyl residues by facilitating synchronized proton transfers. Bioorganic chemistry. 60 (2015), S. 98-101. DOI http://dx.doi.org/10.1016/j.bioorg.2015.04.005
Sergeeva A, Feoktistova N, Prokopovic V, Gorin D, Volodkin D. Design of Porous Alginate Hydrogels by Sacrificial CaCO3 Templates: Pore Formation Mechanism. Advanced material interfaces. 2 (2015), 18, 1500386. DOI http://dx.doi.org/10.1002/admi.201500386
Sergeeva A, Sergeev R, Lengert E, Zakharevich A, Parakhonskiy B, Gorin D, Sergeev S, Volodkin D. Composite magnetite and protein containing CaCO3 Crystals. External manipulation and vaterite → Calcite recrystallization-mediated release performance. ACS Applied Material Interfaces. 7 (2015), 38, S. 21315-25. DOI dx.doi.org/10.1021/acsami.5b05848
Sergeeva A, Volkova EK, Bratashov DN, Shishkin MI, Atkin VS, Markin VS, Skaptsov AA, Volodkin D, Gorin DA. Layer-by-layer assembled highly absorbing hundred-layer films containing a phthalocyanine dye: Fabrication and photosensibilization by thermal treatment. Thin solid films. 583 (2015), S. 60-69. DOI dx.doi.org/10.1016/j.tsf.2015.03.050
Sergeeva AS, Gorin DA, Volodkin DV. In-situ assembly of Ca-alginate gels with controlled pore loading / release capability. Langmuir. 31 (2015), 39, S. 10813-21. DOI dx.doi.org/10.1021/acs.langmuir.5b01529
Skeide MA, Kirsten H, Kraft I, Schaadt G, Müller B, Neef N, Brauer J, Wilcke A, Emmrich F, Boltze J, Friederici AD. Genetic dyslexia risk variant is related to neural connectivity patterns underlying phonological awareness in children. Neuroimage. 118 (2015), S. 414-21. DOI dx.doi.org/10.1016/j.neuroimage.2015.06.024
Stech M, Kubick K. Cell-Free Synthesis Meets Antibody Production: A Review. Antibodies 2015, 4, 12-33; DOI: dx.doi.org/10.3390/antib4010012.
Stetciura IY, Yashchenok A, Masic A, Lyubin EV, Inozemtseva OA, Drozdova MG, Markvichova EA, Khlebtsov BN, Fedyanin AA, Sukhorukov GB, Gorin DA, Volodkin D. Composite SERS-based satellites navigated by optical tweezers for single cell analysis. Analyst. 140 (2015), 15, S. 4981-6. DOI dx.doi.org/10.1039/c5an00392j
Sustr D,Velk N, Duschl C, Volodkin DV. A FRAP-based evaluation of protein diffusion in polyelectrolyte multilayers. European Polymer Journal. 68 (2015), S. 665-670. DOI dx.doi.org/10.1016/j.eurpolymj.2015.03.063
Tan C, Schenk JA, Gajovic-Eichelmann N, Sellrie F, Bier FF. A new one step antigen heterologous homogeneous fluorescence immunoassay for progesterone detection in serum. Talanta. 134 (2015), S. 508–513. DOI dx.doi.org/10.1016/j.talanta.2014.11.062
Tanne J, Jeoung J-H, Peng L, Yarman A, Dietzel B, Schulz B, Schad D, Dobbek H, Wollenberger U, Bier FF, Scheller FW. Direct electron transfer and bioelectrocatalysis by a Hexameric, Heme Protein at nanostructured electrodes. Electroanalysis. 27 (2015, 10, S. 1-7. DOI dx.doi.org/10.1002/elan.201500231
Tröger V, Niemann K, Gärtig C, Kuhlmeier D. Isothermal Amplification and Quantification of Nucleic Acids and its Use in Microsystems. Journal of Nanomedicine & Nanotechnology. 01/2015; 6(3). DOI dx.doi.org/10.4172/2157-7439.1000282
Uyen Nguyen Hoang Phuong, Nenad Gajovic-Eichelmann, Frank. F. Bier, Thanh Ngo Vo Ke. A novel method of immobilizing antigens on gold electrode for immunosensing. Communications in Physics (2015), 25, S. 173-182. DOI dx.doi.org/10.15625/0868-3166/25/2/6239
Vikulina AS, Aleed ST, Paulraj T, Vladimirov YA, Duschl C, von Klitzing R, Volodkin D. Temperature-induced molecular transport through polymer multilayers coated with PNIPAM microgels. Physical chemistry chemical physics. 17 (2015), 19, S. 12771-7. DOI dx.doi.org/10.1039/c5cp01213a
Wachsmuth M, Domin G, Lorenz R, Serfling R, Findeiß S, Stadler PF, Mörl M. Design criteria for synthetic riboswitches acting on transcription. RNA Biology. 12 (2015), 2, 221-31. DOI dx.doi.org/10.1080/15476286.2015.1017235
Wagner L, Wolf R, Zeitschel U, Rossner S, Petersén Å, Leavitt BR, Kästner F, Rothermundt M, Gärtner UT, Gündel D, Schlenzig D, Frerker N, Schade J, Manhart S, Rahfeld JU Demuth HU, von Hörsten S. Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY-cleaving peptidases and potential drug interactions in CNS and periphery. Journal of Neurochemistry. 135 (2015), 5, S. 1019-37. DOI dx.doi.org/10.1111/jnc.13378
Waniek A, Hartlage-Rübsamen M, Höfling C, Kehlen A, Schilling S, Demuth HU, Roßner S. Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes. Biochimica et Biophysica Acta. 1852 (2015), 1, S. 146–155. DOI dx.doi.org/10.1016/j.bbadis.2014.11.011
Werner P, Saur D, Zeisig V, Ettrich B, Patt M, Sattler B, Jochimsen T, Lobsien D, Meyer PM, Bergh FT, Dreyer A, Boltze J, Classen J, Fritzsch D, Hoffmann KT, Sabri O, Barthel H. Simultaneous PET/MRI in stroke: a case series. Journal of cerebral blood flow and metabolism. 35 (2015), 9, S. 1421-5. DOI dx.doi.org/10.1038/jcbfm.2015.158
Won EJ, Kim HR, Park RY, Choi SY, Shin JH, Suh SP, Ryang DW, Szardenings M, Shin MG. Direct confirmation of quiescence of CD34+CD38- leukemia stem cell populations using single cell culture, their molecular signature and clinicopathological implications. BMC Cancer. 15 (2015), 217. DOI dx.doi.org/10.1186/s12885-015-1233-x
Xu LX, Holland H, Kirsten H, Ahnert P, Krupp W, Bauer M, Schober R, Mueller W, Fritzsch D, Meixensberger J, Koschny R. Three gangliogliomas: results of GTG-banding, SKY, genome-wide high resolution SNP-array, gene expression and review of the literature. Neuropathology. 35 (2015), 2, S. 148-57. DOI dx.doi.org/10.1111/neup.12176
Yarman A, Dechtrirat D, Bosserdt M, Jetzschmann KJ, Gajovic-Eichelmann N, Scheller FW. Cytochrome c-Derived Hybrid Systems Based on Moleculary Imprinted Polymers. Electroanalysis. 27 (2015), 3, S. 573-586. DOI dx.doi.org/10.1002/elan.201400592
Zemella A, Thoring L, Hoffmeister C, Kubick S. Cell-Free Protein Synthesis: Pros and Cons of Prokaryotic and Eukaryotic Systems. Chembiochem. 2015 Oct 19. DOI dx.doi.org/10.1002/cbic.201500340 [Epub ahead of print] Article
Zscharnack M, Krause C, Aust G, Thümmler C, Peinemann F, Keller T, Smink JJ, Holland H, Somerson JS, Knauer J, Schulz RM, Lehmann J. Preclinical good laboratory practice-compliant safety study to evaluate biodistribution and tumorigenicity of a cartilage advanced therapy medicinal product (ATMP). J Transl Med. 2015 May 20;13:160. DOI: dx.doi.org/10.1186/s12967-015-0517-x
Zu Siederdissen C, Prohaska SJ, Stadler PF. Algebraic dynamic programming over general data structures. BMC Bioinformatics 16 (2015) Suppl 19, S2. DOI dx.doi.org/10.1186/1471-2105-16-S19-S2

Publikationen 2014

Arnold C, Externbrink F, Hackermüller J, Reiche K. CEMDesigner: Design of custom expression microarrays in the post-ENCODE Era. Journal of Biotechnology. 2014 Nov 10;189:154-6. DOI dx.doi.org/10.1016/j.jbiotec.2014.09.012.
Backofen R, Amman F, Costa F, Findeiß S, Richter AS, Stadler PF. Bioinformatics of prokaryotic RNAs. RNA Biology. 2014 May;11(5):470-83. DOI dx.doi.org/10.4161/rna.28647
Balseanu AT, Buga AM, Catalin B, Wagner DC, Boltze J, Zagrean AM, Reymann K, Schaebitz W, Popa-Wagner A. Multimodal approaches for regenerative stroke therapies: combination of granulocyte colony-stimulating factor with bone marrow mesenchymal stem cells is not superior to G-CSF alone. Frontiers in Aging Neuroscience. 2014 Jun 23;6:130.DOI dx.doi.org/10.3389/fnagi.2014.00130.
Barzon L, Pacenti M, Franchin E, Squarzon L, Sinigaglia A, Ulbert S, Cusinato R, Palù G. Isolation of West Nile virus from urine samples of patients with acute infection. Journal of Clinical Microbiology. 214 Sep;52(9):3411-3. DOI dx.doi.org/10.1128/JCM.01328-14.
Boldt A, Borte S, Fricke S, Kentouche K, Emmrich F, Borte M, Kahlenberg F, Sack U. Eight-color immunophenotyping of T-, B-, and NK-cell subpopulations for characterization of chronic immunodeficiencies. Cytometry B Clinical Cytometry. 2014 May;86(3):191-206.DOI: dx.doi.org/10.1002/cyto.b.21162.
Boldt A, Kahlenberg F, Fricke S, Rasche FM, Sack U. Flow cytometric phenotyping of lymphocytes in patients with systemic lupus erythematosus. Cytometry A. 2014 Jul;85(7):567-9.DOI: dx.doi.org/10.1002/cyto.a.22477
Boldt A, Kentouche K, Fricke S, Borte S, Kahlenberg F, Sack U. Differences in FOXP3 and CD127 expression in Treg-like cells in patients with IPEX syndrome. Clinical Immunoloy. 2014 Jul;153(1):109-11. DOI: dx.doi.org/10.1016/j.clim.2014.04.001
Boltze J, Ayata C, Wagner DC, Plesnila N. Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines. Stroke. 2014 Feb;45(2):357. DOI dx.doi.org/10.1161/STROKEAHA.113.004148
Boltze J, Lukomska B, Jolkkonen J; MEMS–IRBI consortium. Mesenchymal stromal cells in stroke: improvement of motor recovery or functional compensation? Journal of Cerebral Blood Flow and Metabolism. 2014 Aug;34(8):1420-1. DOI dx.doi.org/10.1038/jcbfm.2014.94
Burkhardt J, Blume M, Petit-Teixeira E, Hugo Teixeira V, Steiner A, Quente E, Wolfram G, Scholz M, Pierlot C, Migliorini P, Bombardieri S, Balsa A, Westhovens R, Barrera P, Radstake TR, Alves H, Bardin T, Prum B, Emmrich F, Cornelis F, Ahnert P, Kirsten H. Cellular adhesion gene SELP is associated with rheumatoid arthritis and displays differential allelic expression. PLoS One. 2014 Aug 22;9(8):e103872. DOI dx.doi.org/10.1371/journal.pone.0103872
Chabierski S, Barzon L, Papa A, Niedrig M, Bramson JL, Richner JM, Palù G, Diamond MS, Ulbert S. Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop. BMC Infectious Diseases. 2014 May 9;14:246. DOI dx.doi.org/10.1186/1471-2334-14-246
Cynis H, Funkelstein L, Toneff T, Mosier C, Ziegler M, Koch B, Demuth HU, Hook V. Pyroglutamate-Amyloid-? and Glutaminyl Cyclase Are Colocalized with Amyloid-? in Secretory Vesicles and Undergo Activity-Dependent, Regulated Secretion. Neurodegenerative Diseases. 2014; 14(2):85-97. DOI dx.doi.org/10.1159/000358430
Danckert L, Hoppe S, Bier FF, von Nickisch-Rosenegk M. Rapid identification of novel antigens of Salmonella Enteritidis by microarray-based immunoscreening. Microchimica Acta 02/2014; • 3.43 Impact Factor.
Danielyan L, Beer-Hammer S, Stolzing A, Schäfer R, Siegel G, Fabian C, Kahle P, Biedermann T, Lourhmati A, Buadze M, Novakovic A, Proksch B, Gleiter CH, Frey WH, Schwab M. Intranasal delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer‘s and Parkinson‘s disease. Cell Transplantation. 2014;23 Suppl 1:123-39. DOI dx.doi.org/10.3727/096368914X684970
Dechtrirat D, Gajovic-Eichelmann N, Bier FF, Scheller FW. Hybrid Material for Protein Sensing Based on Electrosynthesized MIP on a Mannose Terminated Self-Assembled Monolayer. Adv Func Mater, 24 (2014): 2233-2239.
Dechtrirat D, Gajovic-Eichelmann N, Wojcik F, Hartmann L, Bier FF, Scheller FW. Electrochemical displacement sensor based on ferrocene boronic acid tracer and immobilized glycan for saccharide binding proteins and E. Coli. Biosens Bioelectron. 58 (2014): 1-8.
De Filette M, Chabierski S, Andries O, Ulbert S, Sanders NN. T cell epitope mapping of the e-protein of west nile virus in BALB/c mice. PLoS One. 2014 Dec 15;9(12):e115343.DOI: dx.doi.org/10.1371/journal.pone.0115343
De Filette M, Soehle S, Ulbert S, Richner J, Diamond MS, Sinigaglia A, Barzon L, Roels S, Lisziewicz J, Lorincz O, Sanders NN. Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge. PLoS One. 2014 Feb 4;9(2):e87837. DOI dx.doi.org/10.1371/journal.pone.0087837
de Vera J-P, Boettger U, Lorek A, Wolter D, Grunow D, Hübers H-W, Spohn T, Noetzel RdlT, Sánchez FJ, Billi D, Baqué M, Rettberg P, Rabbow E, Reitz G, Berger T, Leuko S, Möller R, Bohmeier M, Horneck G, Westall F, Jänchen J, Fritz J, Meyer C, Onofri S, Selbmann L, Zucconi L, Kozyrovska N, Leya T, Foing B, Demets R, Cockell CS, Bryce C, Philips Brown S, Olsson-Francis K, Wagner D, Serrano P, Edwards HGM, Joshi J, Huwe B, Moritz S, Ehrenfreund P, Elsaesser A, Ott S, Meessen J, Feyh N, Szewzyk U, Schulze-Makuch D, Hermelink A, Lasch P. BIOMEX – the Biology and Mars Experiment in space during the EXPOSE-R2 mission on the ISS. GRA. 2014;16.
Diederich K, Schmidt A, Beuker C, Strecker JK, Wagner DC, Boltze J, Schäbitz WR, Minnerup J. Granulocyte colony-stimulating factor (G-CSF) treatment in combination with transplantation of bone marrow cells is not superior to G-CSF treatment alone after cortical stroke in spontaneously hypertensive rats. Frontiers in Cellular Neuroscience. 2014 Dec 4;8:411. DOI dx.doi.org/10.3389/fncel.2014.00411
Dondapati SK, Kreir M, Quast RB, Wüstenhagen DA, Brüggemann A, Fertig N, Kubick S. Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system. Biosens Bioelectron. 2014 Sep 15;59:174-83.
Ehler J, Koball S, Sauer M, Hickstein H, Mitzner S, Benecke R, Zettl UK. Therapeutic plasma exchange in glucocorticosteroid-unresponsive patients with Clinically Isolated Syndrome. Therapeutic Apheresis and Dialysis. 2014 Oct;18(5):489-96.DOI dx.doi.org/10.1111/1744-9987.12176
Ermilova E, Bier FF, Hölzel R. Dielectric measurements of aqueous DNA solutions up to 110 GHz. Phys. Chem. Chem. Phys., 16 (2014): 11256-11264.
Faissner S, Ambrosius B, Schanzmann K, Grewe B, Potthoff A, Münch J, Sure U, Gramberg T, Wittmann S, Brockmeyer N, Uberla K, Gold R, Grunwald T, Chan A. Cytoplasmic HIV-RNA in monocytes determines microglial activation and neuronal cell death in HIV-associated neurodegeneration. Experimental Neurology. 2014 Nov;261:685-97. DOI dx.doi.org/10.1016/j.expneurol.2014.08.011
Fenz SF, Sachse R, Schmidt T, Kubick S. Cell-free synthesis of membrane proteins: tailored cell models out of microsomes. Biochimica et Biophysica Acta. 2014 May;1838(5):1382-8. DOI dx.doi.org/10.1016/j.bbamem.2013.12.009
Flemmig J, Schwarz P, Bäcker I, Leichsenring A, Lange F, Arnhold J. Rapid and reliable determination of the halogenating peroxidase activity in blood samples. Journal of Immunological Methods. 2014 Dec 15;415:46-56. DOI dx.doi.org/10.1016/j.jim.2014.09.003
Fricke S, Hilger N, Fricke C, Schönfelder U, Behre G, Ruschpler P, Boldt A, Oelkrug C, Sack U, Emmrich F. Prevention of graft-versus-host-disease with preserved graft-versus-leukemia-effect by ex vivo and in vivo modulation of CD4(+) T-cells. Cellular and Molecular Life Science. 2014 Jun;71(11):2135-48.DOI: dx.doi.org/10.1007/s00018-013-1476-0
Fricke S, Pfefferkorn C, Wolf D, Riemschneider S, Kohlschmidt J, Hilger N, Fueldner C, Knauer J, Sack U, Emmrich F, Lehmann J. Characterization of the murine myeloid precursor cell line MuMac-E8. PLoS One. 2014 Dec 29;9(12):e113743. DOI: dx.doi.org/10.1371/journal.pone.0113743
Friedrich S, Schmidt T, Geissler R, Lilie H, Chabierski S, Ulbert S, Liebert UG, Golbik RP, Behrens SE. AUF1 p45 promotes West Nile virus replication by an RNA chaperone activity that supports cyclization of the viral genome. Journal of Virology. 2014 Oct;88(19):11586-99.DOI: dx.doi.org/10.1128/JVI.01283-14
Frimmel S, Schipper J, Henschel J, Yu TT, Mitzner SR, Koball S. First description of single-pass albumin dialysis combined with cytokine adsorption in fulminant liver failure and hemophagocytic syndrome resulting from generalized herpes simplex virus 1 infection. Liver Transplantation. 2014 Dec;20(12):1523-4. DOI dx.doi.org/10.1002/lt.24005
Fronz U, Deten A, Baumann F, Kranz A, Weidlich S, Härtig W, Nieber K, Boltze J, Wagner DC. Continuous adenosine A2A receptor antagonism after focal cerebral ischemia in spontaneously hypertensive rats. Naunyn Schmiedeberg's Archives of Pharmacoloy. 2014 Feb;387(2):165-73. DOI dx.doi.org/10.1007/s00210-013-0931-7
Füllbrandt M, Ermilova E, Asadujjaman A, Hölzel R, Bier FF, von Klitzing R, Schönhals A. Dynamics of Linear Poly(N-isopropylacrylamide) in Water around the Phase Transition Investigated by Dielectric Relaxation Spectroscopy. J Phys Chem B. 118 (2014): 3750-3759.
Grunwald T, Tenbusch M, Schulte R, Raue K, Wolf H, Hannaman D, de Swart RL, Uberla K, Stahl-Hennig C. Novel vaccine regimen elicits strong airway immune responses and control of respiratory syncytial virus in nonhuman primates. Journal of Virology. 2014 Apr;88(8):3997-4007. DOI dx.doi.org/10.1128/JVI.02736-13
Haag M, Augst H, Kebbel K, Ringe J, Van Linthout S, Thielemann D, Kellert C, Schmiedeknecht G, Tschoepe C, Sittinger M. Human cardiac derived cells for the treatment of chronic heart failure - from bench to bedside. Kooperationsforum - Technologien für zellbasierte Therapien, Erlangen 2014, Tagungsband S. 118-19.
Hacht AV, Seifert O, Menger M, Schütze T, Arora A, Konthur Z, Neubauer P, Wagner A, Weise C, Kurreck J. Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic Acids Res. (2014), 42 (10): 6630-6644; doi: 10.1093/nar/gku290. PMID: 24771345.
Hackermüller J, Reiche K, Otto C, Hösler N, Blumert C, Brocke-Heidrich K, Böhlig L, Nitsche A, Kasack K, Ahnert P, Krupp W, Engeland K, Stadler PF, Horn F. Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs. Genome Biology. 2014 Mar 4;15(3):R48. DOI dx.doi.org/10.1186/gb-2014-15-3-r48
Hass J, Walton E, Kirsten H, Turner J, Wolthusen R, Roessner V, Sponheim SR, Holt D, Gollub R, Calhoun VD, Ehrlich S. Complexin2 modulates working memory-related neural activity in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 2014 Oct 9. [Epub ahead of print] DOI dx.doi.org/10.1007/s00406-014-0550-4
Herbel S, von Nickisch-Rosenegk M, Kuhn M, Murugaiyan J, Wieler LH, Guenther S. Specific TaqMan Probes for the Identification and Quantification of Lactobacilli in Pharmaceuticals. Journal of Probiotics & Health. 02/2014; 2(1).
Hoffmann A, Stoffel MH, Nitzsche B, Lobsien D, Seeger J, Schneider H, Boltze J. The ovine cerebral venous system: comparative anatomy, visualization, and implications for translational research. PLoS One. 2014 Apr 15;9(4):e92990. DOI dx.doi.org/10.1371/journal.pone.0092990
Hoffmann S, Otto C, Doose G, Tanzer A, Langenberger D, Christ S, Kunz M, Holdt LM, Teupser D, Hackermüller J, Stadler PF. A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection. Genome Biology. 2014 Feb 10;15(2):R34. DOI dx.doi.org/10.1186/gb-2014-15-2-r34
Höfling C, Indrischek H, Höpcke T, Waniek A, Cynis H, Koch B, Schilling S, Morawski M, Demuth HU, Roßner S, Hartlage-Rübsamen M. Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC. International Journal of Developmental Neuroscience. 2014 Aug; 36:64-73. DOI dx.doi.org/10.1016/j.ijdevneu.2014.05.008
Hoppe S, Bier FF, von Nickisch-Rosenegk M. Identification of antigenic proteins of the nosocomial pathogen Klebsiella pneumoniae. PLoS One 9(10): e110703. Doi dx.doi.org/10.1371/journal.pone.0110703
Hovestädt M, Memczak H, Pleiner D, Zhang X, Rappich J, Bier FF, Stöcklein WFM. Characterization of a new maleimido functionalization of gold for surface plasmon resonance spectroscopy. J. Mol. Recognit. 2014, in press, DOI: 10.1002/jmr.2396.
Hüttl C, Hettrich C, Riedel M, Henklein P, Rawel H, Bier FF. Development of peptidyl lysine dendrons: 1,3-Dipolar cycloaddition for peptide coupling and antibody recognition. Chemical Biology and Drug Design. 2014 Oct 7. DOI dx.doi.org/10.1111/cbdd.12444
Kaiser D, Weise G, Möller K, Scheibe J, Pösel C, Baasch S, Gawlitza M, Lobsien D, Diederich K, Minnerup J, Kranz A, Boltze J, Wagner DC. Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease. Acta Neuropatholica Communications. 2014 Dec 18;2(1):169. DOI dx.doi.org/10.1186/s40478-014-0169-8
Kersting S, Rausch V, Bier FF, von Nickisch-Rosenegk M. Rapid detection of Plasmodium falciparum with isothermal recombinase polymerase amplification and lateral flow analysis. Malaria J., 13 (2014):99. (e1-e9).
Kersting S, Rausch V, Bier FF, von Nickisch-Rosenegk M. Multiplex isothermal solid-phase recombinase polymerase amplification for the specific and fast DNA-based detection of three bacterial pathogens. Mikrochim Acta. 181 (2014):1715-1723.
Klammt S, Mitzner SR, Reisinger EC, Stange J. No sustained impact of intermittent extracorporeal liver support on thrombocyte time course in a randomized controlled albumin dialysis trial. Therapeutic Apheresis and Dialysis. 2014 Oct;18(5):502-8. DOI dx.doi.org/10.1111/1744-9987.12124
Korenic A, Boltze J, Deten A, Peters M, Andjus P, Radenovi? L. Astrocytic Mitochondrial Membrane Hyperpolarization following Extended Oxygen and Glucose Deprivation. PLoS One. 2014 Feb 28;9(2):e90697. doi: 10.1371/journal.pone.0090697.
Kozma P, Kehl F, Ehrentreich-Förster E, Stamm C, Bier FF. Integrated planar optical waveguide interferometer biosensors: A comparative review. Biosens. Bioelectron. 58 (2014):287-307.
Kucharík M, Hofacker IL, Stadler PF, Qin J. Basin hopping graph: a computational framework to characterize RNA folding landscapes. Bioinformatics. 2014 Jul 15;30(14):2009-17. DOI dx.doi.org/10.1093/bioinformatics/btu156
Kumke M, Eisold U, Sellrie F, Schenk J, Stöcklein W, Lenz C. Bright or dark immune complexes of anti-TAMRA antibodies for tailored fluorescence based bioanalysis. Anal. Bioanal. Chem. 2014 eingereicht.
Laux EM, Kaletta UC, Bier FF, Wenger C, Hölzel R. Functionality of dielectrophoretically immobilized enzyme molecules. Electrophoresis. 35 (2014): 459-466.
Lechner M, Hernandez-Rosales M, Doerr D, Wieseke N, Thévenin A, Stoye J, Hartmann RK, Prohaska SJ, Stadler PF. Orthology detection combining clustering and synteny for very large datasets. PLoS One. 2014 Aug 19;9(8):e105015. DOI dx.doi.org/10.1371/journal.pone.0105015
Lehmann J, Härtig W, Seidel A, Füldner C, Hobohm C, Grosche J, Krueger M, Michalski D. Inflammatory cell recruitment after experimental thromboembolic stroke in rats. Neuroscience. 2014 Oct 24; 279:139-154. DOI: dx.doi.org/10.1016/j.neuroscience.2014.08.023
Lehmann J, Härtig W, Seidel A, Füldner C, Fuhs T, Hobohm C, Grosche J, Krüger M, Michalski D. Reevaluating the local inflammatory response in stroke – a translational-inspired study using the human-like thromboembolic model in rats. Neuroscience (2014) Aug 26. pii: S0306-4522(14)00699-X. doi: 10.1016/j.neuroscience.2014.08.023. [Epub ahead of print].
Magnusson SE, Karlsson KH, Reimer JM, Corbach-Söhle S, Patel S, Richner JM, Nowotny N, Barzon L, Bengtsson KL, Ulbert S, Diamond MS, Stertman L. Matrix-M™ adjuvanted envelope protein vaccine protects against lethal lineage 1 and 2 West Nile virus infection in mice. Vaccine. 2014 Feb 7;32(7):800-8. DOI dx.doi.org/10.1016/j.vaccine.2013.12.030
Mann M, Nahar F, Schnorr N, Backofen R, Stadler PF, Flamm C. Atom mapping with constraint programming. Algorithms for Molecular Biology. 2014 Nov 29;9(1):23. DOI dx.doi.org/10.1186/s13015-014-0023-3
Minnerup J, Wagner DC, Strecker JK, Pösel C, Sevimli-Abdis S, Schmidt A, Schilling M, Boltze J, Diederich K, Schäbitz WR. Bone marrow-derived mononuclear cells do not exert acute neuroprotection after stroke in spontaneously hypertensive rats. Frontiers in Cellular Neuroscience. 2014 Jan 8;7:288. DOI dx.doi.org/10.3389/fncel.2013.00288
Möller K, Boltze J, Pösel C, Seeger J, Stahl T, Wagner DC. Sterile inflammation after permanent distal MCA occlusion in hypertensive rats. Journal of Cerebral Blood Flow and Metabolism. 2014 Feb;34(2):307-15. DOI dx.doi.org/10.1038/jcbfm.2013.199
Morawski M, Schilling S, Kreuzberger M, Waniek A, Jäger C, Koch B, Cynis H, Kehlen A, Arendt T, Hartlage-Rübsamen M, Demuth HU, Roßner S. Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-beta load and cognitive decline in Alzheimer‘s disease. Journal of Alzheimer‘s Disease. 2014;39(2):385-400. DOI dx.doi.org/10.3233/JAD-131535
Mueller B, Ahnert P, Burkhardt J, Brauer J, Czepezauer I, Quente E, Boltze J, Wilcke A, Kirsten H. Genetic risk variants for dyslexia on chromosome 18 in a German cohort. Genes, Brain and Behavior. 2014 Mar;13(3):350-6. DOI dx.doi.org/10.1111/gbb.12118
Nickels PC, Ke Y, Jungmann R, Smith DM, Leichsenring M, Shih WM, Liedl T, Högberg B. DNA origami structures directly assembled from intact bacteriophages. Small. 2014 May 14;10(9):1765-9. DOI dx.doi.org/10.1002/smll.201303442
Oelkrug C, Lange CM, Wenzel E, Fricke S, Hartke M, Simasi J, Schubert A. Analysis of the tumoricidal and anti-cachectic potential of curcumin. Anticancer Research. 2014 Sep;34(9):4781-8.
Oelkrug C, Hilger N, Schönfelder U, Boltze J, Sack U, Fricke C, Hildebrandt G, Keller T, Emmrich F, Fricke S. Modelling hematological parameters after total body irradiation. International Journal of Radiation Biology. 2014 Jul;90(7):538-46. DOI: dx.doi.org/10.3109/09553002.2014.899443
Oelkrug C, Ramage JM. Enhancement of T cell recruitment and infiltration into tumours. Clinical and Experimental Immunology. 2014 Oct;178(1):1-8. DOI dx.doi.org/10.1111/cei.12382
Otto S, Kaletta U, Bier FF, Wenger C, Hölzel R. Dielectrophoretic immobilisation of antibodies on microelectrode arrays. Lab Chip. 14 (2014): 998-1004.
Patra D, Fasold M, Langenberger D, Steger G, Grosse I, Stadler PF. plantDARIO: web based quantitative and qualitative analysis of small RNA-seq data in plants. Frontiers in Plant Science. 2014 Dec 23;5:708. DOI dx.doi.org/10.3389/fpls.2014.00708
Paulraj T, Feoktistova N, Velk N, Uhlig K, Duschl C, Volodkin D. Microporous polymeric 3D scaffolds templated by the layer-by-layer self-assembly. Macromolecular rapid communications. 2014 Aug;35(16):1408-13. DOI dx.doi.org/10.1002/marc.201400253
Pieroh P, Koch M, Wagner DC, Boltze J, Ehrlich A, Ghadban C, Hobusch C, Birkenmeier G, Dehghani F. Temporal dynamics of glyoxalase 1 in secondary neuronal injury. PLoS One. 2014 Feb 3;9(2):e87364. DOI dx.doi.org/10.1371/journal.pone.0087364
Pösel C, Scheibe J, Kranz A, Bothe V, Quente E, Fröhlich W, Lange F, Schäbitz WR, Minnerup J, Boltze J, Wagner DC. Bone marrow cell transplantation time-dependently abolishes efficacy of granulocyte colony-stimulating factor after stroke in hypertensive rats. Stroke. 2014 Aug;45(8):2431-7.DOI dx.doi.org/10.1161/STROKEAHA.113.004460
Pösel C, Uri A, Schulz I, Boltze J, Weise G, Wagner DC. Flow cytometric characterization of brain dendritic cell subsets after murine stroke. Experimental and Translational Stroke Medicine. 2014 Nov 4;6(1):11. DOI dx.doi.org/10.1186/2040-7378-6-11
Pratsch K, Wellhausen R, Seitz H. Advances in the quantification of protein microarrays. Curr Opin Chem Biol Feb 2014; Vol 18; 16-20.
Prill S, Jaeger, MS, Duschl C. Long-term microfluidic glucose and lactate monitoring in hepatic cell culture. Biomicrofluidics. (2014) 8, 034102.
Qin J, Fricke M, Marz M, Stadler PF, Backofen R. Graph-distance distribution of the Boltzmann ensemble of RNA secondary structures. Algorithms for Molecular Biology. 2014 Sep 11;9:19. DOI dx.doi.org/10.1186
Rapsch K, Bier FF, von Nickisch-Rosenegk M. Rational Design of Artificial Beta-Strand-Forming Antimicrobial Peptides with Biocompatible Properties. Mol Pharm. 2014 Oct 6;11(10):3492-502. doi: 10.1021/mp500271c. Epub 2014 Sep 22. PubMed PMID: 25192319.
Reiche K, Kasack K, Schreiber S, Lüders T, Due EU, Naume B, Riis M, Kristensen VN, Horn F, Børresen-Dale AL, Hackermüller J, Baumbusch LO. Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes. PLoS One. 2014 Sep 29;9(9):e106076. DOI dx.doi.org/10.1371/journal.pone.0106076
Reinhardt A, Horn M, Pieper J gen. Schmauck, Bröhl A, Giernoth R, Oelkrug C, Schubert A, Neundorf I. Novel imidazolium salt-peptide conjugates and their antimicrobial activity. Bioconjugate Chemistry. 2014 Dec 17;25(12):2166-74. DOI dx.doi.org/10.1021/bc500510c
Roshyara NR, Kirsten H, Horn K, Ahnert P, Scholz M. Impact of pre-imputation SNP-filtering on genotype imputation results. BMC Genetics. 2014 Aug 12;15:88. DOI dx.doi.org/10.1186/s12863-014-0088-5
Sachse R, Dondapati SK, Fenz SF, Schmidt T, Kubick S. Membrane protein synthesis in cell-free systems: from bio-mimetic systems to bio-membranes. FEBS Letter. 2014 Aug 25;588(17):2774-81. DOI dx.doi.org/10.1016/j.febslet.2014.06.007
Sahyoun AH, Bernt M, Stadler PF, Tout K. GC skew and mitochondrial origins of replication. Mitochondrion. 2014 Jul;17:56-66. DOI dx.doi.org/10.1016/j.mito.2014.05.009
Sandetskaya N, Naumann A, Hennig K, Kuhlmeier D. Specific enrichment of prokaryotic DNA using a recombinant DNA-binding protein. Analytical and Bioanalytical Chemistry. 2014 Jun;406(15):3755-62. DOI dx.doi.org/10.1007/s00216-014-7787-7.
Scheller FW, Yarman A, Bachmann T, Hirsch T, Kubick S, Renneberg R, Schumacher S, Wollenberger U, Teller C, Bier FF. Future of Biosensors: A Personal View. Adv Biochem Eng Biotechnol. 140 (2014):1-28.
Schmidt S, Uhlig K, Duschl C, Volodkin DV. Stability and Cell Uptake of Calcium Carbonate Templated Insulin Microparticles. Acta Biomaterialia (2014), 10, S. 1423-1430.
Schmiedeknecht G. Besondere Herausforderungen bei der Herstellung von ATMP. »The Product is the Process – Is it?« Qualitätsaspekte bei der Herstellung von ATMP, November 4, 2014, Berlin.
Schmiedeknecht G. Translational research initiatives in Germany: Experiences on cell processing services. Clinical Evaluation, Vol. 42, No. 1, Jul. 2014, page 87-94.
Schmiedeknecht G, Kebbel K, Sonnabend C, Wagner M, Gryczka M, Stella M, Ganjei K, Bosch M, Powers LF. Process transfer of DCVax®-L to Europe and initiation of a phase III clinical trial in UK and Germany. ISCT (International Society for Cell Therapy) 2014 Annual Meeting, Paris, France, April 23–26, 2014.
Schmiedeknecht G, Kebbel K. Challenges of Manufacturing of ATMP’s for clinical trials. PACT (Platform for Advanced Cellular Therapies Austria) Foundation Symposium, Vienna, Austria, April 3–4, 2014.
Schmiedeknecht G. Translational Research Initiatives in Germany: Experiences on Cell Processing Services. Translational Research Center Workshop, organized by the Foundation for Biomedical Research and Innovation (FBRI) and Ministry of Education, Culture, Sports, Science and Technology (MEXT), Tokyo, Japan, February 27, 2014.
Schreml S, Meier RJ, Kirschbaum M et al.Luminescent Dual Sensors Reveal Extracellular pH-Gradients and Hypoxia on Chronic Wounds That Disrupt Epidermal Repair Theranostics. (2014), 4, S. 721-735.
Schulz I, Engel C, Niestroj AJ, Kehlen A, Rahfeld JU, Kleinschmidt M, Lehmann K, Roßner S, Demuth HU. A non-canonical function of eukaryotic elongation factor 1A1: regulation of interleukin-6 expression. Biochimica et Biophysica Acta – Molecular Cell Research. 2014 May;1843(5):965-75. DOI dx.doi.org/10.1016/j.bbamcr.2014.01.022
Schwertassek U, Haque A, Krishnan N, Greiner R, Weingarten L, Dick TP, Tonks NK. Reactivation of oxidized PTP1B and PTEN by thioredoxin 1. FEBS Journal. 2014 Aug;281(16):3545-58. DOI: dx.doi.org/10.1111/febs.12898
Sharma A, Wendland R, Sung B, Wu W, Grunwald T, Worgall S. Maternal immunization with chimpanzee adenovirus expressing RSV fusion protein protects against neonatal RSV pulmonary infection. Vaccine. 2014 Sep 29;32(43):5761-8. DOI dx.doi.org/10.1016/j.vaccine.2014.08.049
Simasi J, Oelkrug C, Schubert A, Nieber K, Gillissen A. The role of BIM-EL and BCL2-? on the efficacy of erlotinib and gefitinib in lung cancer. Respiratory Physiology and Neurobioly. 2014 Oct 6. pii: S1569-9048(14):259-6.DOI: dx.doi.org/10.1016/j.resp.2014.09.022
Simasi J, Schubert A, Oelkrug C, Gillissen A, Nieber K. Primary and secondary resistance to tyrosine kinase inhibitors in lung cancer. Anticancer Res. 2014 Jun;34(6):2841-50.
Stech M, Hust M, Schulze C, Dübel S, Kubick S. Cell-free eukaryotic systems for the production, engineering, and modification of scFv antibody fragments. Engineering in Life Sciences. 20104;14(4):387–398. DOI dx.doi.org/10.1002/elsc.201400036
Stech M, Quast RB, Sachse R, Schulze C, Wüstenhagen DA, Kubick S. A continuous-exchange cell-free protein synthesis system based on extracts from cultured insect cells. PLoS One 9 (2014) e96635.
Tanne J, Dietzel B, Scheller FW, Bier F. Nanohybrid Materials Consisting of Poly[(3-aminobenzoic acid)-co-(3-aminobenzenesulfonic acid)-co-aniline] and Multiwalled Carbon Nanotubes for Immobilization of Redox Active Cytochrome c. Electroanalysis 26 (2014): 732–738.
Tanne J, Kracher D, Dietzel B, Schulz B, Ludwig R, Lisdat F, Scheller FW, Bier FF. Carboxylated or aminated polyaniline-multiwalled carbon nanotubes nanohybrids for immobilization of cellobiose dehydrogenase on gold electrodes. Biosensors. 2014 Oct 22;4(4):370-386. DOI dx.doi.org/10.3390/bios4040370
Tönjes A, Scholz M, Breitfeld J, Marzi C, Grallert H, Gross A, Ladenvall C, Schleinitz D, Krause K, Kirsten H, Laurila E, Kriebel J, Thorand B, Rathmann W, Groop L, Prokopenko I, Isomaa B, Fasshauer M, Klöting N, Gieger C, Blüher M, Sturmvoll M, Kovacs P. Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genetics. 2014 Dec 18;10(12):e1004854. DOI dx.doi.org/10.1371/journal.pgen.1004854
Ueberham U, Rohn S, Ueberham E, Wodischeck S, Hilbrich I, Holzer M, Brückner MK, Gruschka H, Arendt T. Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease. Neuropathology and Applied Neurobiology. 2014 Dec;40(7):815-32.DOI: dx.doi.org/10.1111/nan.12163
Ueberham E, Glockner P, Gohler C, Straub BK, Teupser D, Schonig K, Braeuning A, Hohn AK, Jerchow B, Birchmeier W, Gaunitz F, Arendt T, Sansom O, Gebhardt R, Ueberham U. Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a Negative Tumors. Molecular Cancer Research, 2014 Sep 30. DOI: dx.doi.org/10.1158/1541-7786.MCR-14-0278-T
Uhlig K, Boerner HG, Wischerhoff E, Lutz JF, Jaeger MS, Laschewsky A, Duschl C. On the interaction of adherent cells with thermoresponsive polymer coatings. Polymers. (2014), 6, 1164-1177.
Ulbert S, Magnusson SE. Technologies for the development of West Nile virus vaccines. Future Microbiology. 2014;9(10):121-32. DOI dx.doi.org/10.2217/fmb.14.67
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Vochem R, Einenkel J, Horn LC, Ruschpler P. Die Bedeutung der Tumorstammzellhypothese für das Verständnis des Ovarialkarzinoms. Der Pathologe. 2014 Jul;35(4):361-70. DOI dx.doi.org/10.1007/s00292-014-1910-6
von Klitzing R, Volodkin DV. Competing mechanisms in polyelectrolyte multilayer formation and swelling: Polycation–polyanion pairing vs. polyelectrolyte–ion pairing. Curr. Opinion Colloid Interface Sci. (2014), in press.
Wagner DC, Pösel C, Schulz I, Schicht G, Boltze J, Lange F, Scheibe J, Möller K, Weise G. Allometric dose retranslation unveiled substantial immunological side effects of granulocyte colony-stimulating factor after stroke. Stroke. 2014 Feb;45(2):623-6. DOI dx.doi.org/10.1161/STROKEAHA.113.003812
Wege AK, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, Lehmann J. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. mAbs. 2014 Jul-Aug;6(4):968-77. DOI dx.doi.org/10.4161/mabs.29111
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Publikationen 2013

Arnold C, Stadler PF, Prohaska SJ. Chromatin computation: Epigenetic inheritance as a pattern reconstruction problem. Journal of theoretical biology 336 (2013), S. 61–74. DOI dx.doi.org/10.1016/j.jtbi.2013.07.012
Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, Saliba F, Sauerbruch T, Klammt S, Ockenga J, Pares A, Wendon J, Brünnler T, Kramer L, Mathurin P, de la Mata M, Gasbarrini A, Müllhaupt B, Wilmer A, Laleman W, Eefsen M, Sen S, Zipprich A, Tenorio T, Pavesi M, Schmidt HH, Mitzner S, Williams R, Arroyo V; RELIEF study group. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial. Hepatology. 57(2013), 3, S. 1153–62. DOI dx.doi.org/10.1002/hep.26185
Becker A, Kohlmann S, Alexandru A, Jagla W, Canneva F, Bäuscher C, Cynis H, Sedlmeier R, Graubner S, Schilling S, Demuth HU, von Hörsten S. Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration. BMC Neurosci. 2013 Oct 1;14:108. DOI dx.doi.org/10.1186/1471-2202-14-108
Bernt M, Bleidorn C, Braband A, Dambach J, Donath A, Fritzsch G, Golombek A, Hadrys H, Jühling F, Meusemann K, Middendorf M, Misof B, Perseke M, Podsiadlowski L, Reumont B von, Schierwater B, Schlegel M, Schrödl M, Simon S, Stadler PF, Stöger I, Struck TH. A comprehensive analysis of bilaterian mitochondrial genomes and phylogeny. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 352–364. DOI dx.doi.org/10.1016/j.ympev.2013.05.002
Bernt M, Braband A, Middendorf M, Misof B, Rota-Stabelli O, Stadler PF. Bioinformatics methods for the comparative analysis of metazoan mito-chondrial genome sequences. Molecular phylogenetics and evolution 69 (2013), 2, S. 320–327. DOI dx.doi.org/10.1016/j.ympev.2012.09.019
Bernt M, Braband A, Schierwater B, Stadler PF. Genetic aspects of mitochondrial genome evolution. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 328–338. DOI dx.doi.org/10.1016/j.ympev.2012.10.020
Bernt M, Donath A, Jühling F, Externbrink F, Florentz C, Fritzsch G, Pütz J, Middendorf M, Stadler PF. MITOS: improved de novo metazoan mitochondrial genome annotation. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 313–319. DOI dx.doi.org/10.1016/j.ympev.2012.08.023
Biadglegne F, Tesfaye W, Anagaw B, Tessema B, Debebe T, Anagaw B, Mulu A, Sack U, Rodloff A.C. Tuberculosis lymphadenitis in Ethiopia. Japanese journal of infectious diseases : JJID 66 (2013), 4, S. 263–268.
Blumert C, Kalkhof S, Broche-Heidrich K, Kohajda T, von Bergen M, Horn F. Analysis of the STAT3 intercatome using in-situ biotinylation and SILAC. Journal of Proteomics. 94 (2013), S. 370–386. DOI dx.doi.org/10.1016/j.jprot.2013.08.021
Bodammer P, Kerkhoff C, Maletzki C, Lamprecht G. Bovine colostrum increases pore-forming claudin-2 protein expression but paradoxically not ion permeability possibly by a change of the intestinal cytokine milieu. PLoS One. 8 (2013), 5, e64210. DOI dx.doi.org/10.1371/journal.pone.0064210
Bodammer P, Zirzow E, Klammt S, Maletzki C, Kerkhoff C. Alteration of DSS-mediated immune cell redistribution in murine colitis by oral colostral immunoglobulin. BMC immunology. 14 (2013), e10. DOI dx.doi.org/10.1186/1471-2172-14-10
Boll K, Reiche K, Kasack K, Mörbt N, Kretzschmar AK, Tomm JM, Verhaegh G, Schalken J, von Bergen M, Horn F, Hackermüller J. MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma. Oncogene. 32 (2013), S. 277–285. DOI dx.doi.org/10.1038/onc.2012.55
Breitrück A, Sparmann G, Mitzner S, Kerkhoff C. Establishment of a novel extracorporeal bowel model to study luminal approaches to treat inflammatory bowel disease. Disease Models and Mechanisms. 6 (2013), 6, S. 1487–93. DOI dx.doi.org/10.1242/dmm.011734
Chabierski S, Makert GR, Kerzhner A, Barzon L, Fiebig P, Liebert UG, Papa A, Richner JM, Niedrig M, Diamond MS, Palù G, Ulbert S. Antibody responses in humans infected with newly emerging strains of West Nile Virus in Europe. PLoS One. 8 (2013), 6, e66507. DOI dx.doi.org/10.1371/journal.pone.0066507
Cynis H, Kehlen A, Haegele M, Hoffmann T, Heiser U, Fujii M, Shibazaki Y, Yoneyama H, Schilling S, Demuth HU. Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice. Int J Exp Pathol. 2013 Jun; 94(3):217–25. DOI dx.doi.org/10.1111/iep.12020 Epub 2013 Apr 8.
Dieterich C, Stadler PF. Computational biology of RNA interactions. Wiley interdisciplinary reviews. RNA. Online resource 4 (2013), Nr. 1, S. 107–120. DOI dx.doi.org/10.1002/wrna.1147
Dirnagl, U, Hakim A, MacLeod M, Fisher M, Howells D, Alan SM, Steinberg G, Planas A, Boltze J, Savitz S, Iadecola C. Meairs S. A concerted appeal for international cooperation in preclinical stroke research. Stroke. 44 (2013), 6, S. 1754–1760. DOI dx.doi.org/10.1161/STROKEAHA.113.000734
Doose G, Alexis M, Kirsch R, Findeis S, Langenberger D, Machne R, Mörl M, Hoffmann S, Stadler PF. Mapping the RNA-Seq trash bin: Unusual transcripts in prokaryotic transcriptome sequencing data. RNA biology 10 (2013), Nr. 7, S. 1204–1210. DOI dx.doi.org/10.4161/rna.24972
Faust D, Kletting S, Ueberham E, Dietrich C. Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells. Toxicology letters. 223 (2013), 1, S. 73–80. DOI dx.doi.org/10.1016/j.toxlet.2013.08.022
Fricke S, Hilger N, Fricke C, Schönfelder U, Behre G, Ruschpler P, Boldt A, Oelkrug C, Sack U, Emmrich F. Prevention of graft-versus-host-disease with preserved graft-versus-leukemia-effect by ex vivo and in vivo modulation of CD4+ T-cells. Cellular and Molecular Life Sciences. 2013 Sep 26. [Epub ahead of print]
Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, Lemere CA. Pyroglutamate-3 amyloid-beta deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models. Am J Pathol. 2013 Aug;183(2):369-81. DOI dx.doi.org/10.1016/j.ajpath.2013.05.005 Epub 2013 Jun 7.
Güttler BH, Cynis H, Seifert F, Ludwig HH, Porzel A, Schilling S. A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues. Amino Acids. 44 (2013), 4, S. 1205–14. DOI dx.doi.org/10.1007/s00726-012-1454-0
Hass J, Walton E, Kirsten H, Liu J, Priebe L, Wolf C, Karbalai N, Gollub R, White T, Roessner V, Müller KU, Paus T, Smolka MN, Schumann G, IMAGEN Consortium, Scholz M, Cichon S, Calhoun V, Ehrlich S. A genome-wide association study suggests novel loci associated with a Schizophrenia-related brain-based phenotype. PLoS One. 8 (2013), 6, e64872. DOI dx.doi.org/10.1371/journal.pone.0064872
Hellvard A, Maresz K, Schilling S, Graubner S, Heiser U, Jonsson R, Cynis H, Demuth HU, Potempa J, Mydel P. Glutaminyl cyclases as novel targets for the treatment of septic arthritis. Journal of Infectious Diseases. 207 (2013), 5, S. 768–77. DOI dx.doi.org/10.1093/infdis/jis729
Hodzic M, Naaldijk Y, Stolzing A. Regulating aging in adult stem cells with microRNA. Zeitschrift für Gerontologie und Geriatrie. 46 (2013), 7, S. 629–34. DOI dx.doi.org/10.1007/s00391-013-0531-7
Holland H, Xu LX, Ahnert P, Kirsten H, Koschny R, Bauer M, Schober R, Meixensberger J, Krupp W. Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma. Pathology – research and practice. 209 (2013), 9, S. 541–7. DOI dx.doi.org/10.1016/j.prp.2013.06.001
Hubicka J, Jost J, Long Y, Stadler PF, Yang L. Relations between graphs. Ars mathematica contemporanea 6 (2013), Nr. 2, S. 323–350.
Jiang SN, Park SH, Lee HJ, Zheng JH, Kim HS, Bom HS, Hong Y, Szardenings M, Shin MG, Kim SC, Ntziachristos V, Choy HE, Min JJ. Engineering of bacteria for the visualization of targeted delivery of a cytolytic anticancer agent. Molecular Therapy. 21 (2013), 11, S. 1985–95. DOI dx.doi.org/10.1038/mt.2013.183
Kehlen A, Haegele M, Menge K, Gans K, Immel UD, Hoang-Vu C, Klonisch T, Demuth HU. Role of glutaminyl cyclases in thyroid carcinomas. Endocr Relat Cancer. 2013 Feb 18;20(1):79-90. DOI dx.doi.org/10.1530/ERC-12-0053 Print 2013 Feb.
Kolenko P, Koch B, Rahfeld JU, Schilling S, Demuth HU, Stubbs MT. Structure of glutaminyl cyclase from Drosophila melanogaster in space group I4. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69 (Pt 4): 358-61. DOI dx.doi.org/10.1107/S1744309113005575 Epub 2013 Mar 28.
Langenberger D, Cakir MV, Hoffmann S, Stadler PF. Dicer-processed small RNAs: Rules and exceptions. Journal of experimental zoology. Part B, Molecular and developmental evolution 320B (2013), Nr. 1, S. 35–46. DOI dx.doi.org/10.1002/jez.b.22481
Lechner M, Marz M, Ihling C, Sinz A, Stadler PF, Krauss V. The correlation of genome size and DNA methylation rate in metazoans. Theory in Biosciences 132 (2013), Nr. 1, S. 47–60. DOI dx.doi.org/10.1007/s12064-012-0167-y
Lehmann J, Stadler PF, Krauss V. Near intron pairs and the metazoan tree. Molecular phylogenetics and evolution 66 (2013), Nr. 3, S. 811–823. DOI dx.doi.org/10.1016/j.ympev.2012.11.012
Lipfert J, Ödemis V, Wagner DC, Boltze J, Engele J. CXCR4 and CXCR7 form a functional receptor unit for SDF-1/CXCL12 in primary rodent microglia. Neuropathology and applied neurobiology. 39 (2013), 6, S. 667–80. DOI dx.doi.org/10.1111/nan.12015
Lison H, Happel MF, Schneider F, Baldauf K, Kerbstat S, Seelbinder B, Schneeberg J, Zappe M, Goldschmidt J, Budinger E, Schröder UH, Ohl FW, Schilling S, Demuth HU, Scheich H, Reymann KG, Rönicke R. Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death. Neurobiol Dis. 2014 Mar;63:62-73. DOI dx.doi.org/10.1016/j.nbd.2013.11.014 Epub 2013 Nov 27.
Lobsien D, Dreyer AY, Stroh A, Boltze J, Hoffmann KT. Imaging of VSOP labeled stem cells in agarose phantoms with susceptibility weighted and T2* weighted MR Imaging at 3T: determination of the detection limit. PLoS One. 8 (2013), 5, e62644. DOI dx.doi.org/10.1371/journal.pone.0062644
Mitzner S. Stellenwert der MARS-Dialyse beim Acute-on-chronic-Leberversagen. Zeitschrift für Gastroenterologie. 51 (2013), 10, S. 1193–4. DOI dx.doi.org/10.1055/s-0033-1350351
Mitzner SR, Gloger M, Henschel J, Koball S. Improvement of hemodynamic and inflammatory parameters by combined hemoadsorption and hemodiafiltration in septic shock: a case report. Blood Purification. 35 (2013),4, S. 314–5. DOI dx.doi.org/10.1159/000351206
Müller SA, Findeiß S, Pernitzsch SR, Wissenbach DK, Stadler PF, Hofacker IL, Bergen M. von, Kalkhof S. Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics. Journal of Proteomics 86 (2013), S. 27–42. DOI dx.doi.org/10.1016/j.jprot.2013.04.036
Pachernegg S, Joshi I, Muth-Köhne E, Pahl S, Münster Y, Terhag J, Karus M, Werner M, Ma-Högemeier ZL, Körber C, Grunwald T, Faissner A, Wiese S, Hollmann M. Undifferentiated embryonic stem cells express ionotropic glutamate receptor mRNAs. Frontiers in Neuroscience. 7 (2013), 241, 12 S. DOI dx.doi.org/10.3389/fncel.2013.00241
Pönisch W, Moll B, Bourgeois M, Andrea M, Schliwa T, Heyn S, Schmalfeld M, Edelmann T, Becker C, Hoffmann FA, Schwarzer A, Kreibich U, Egert M, Stiegler R, Krahl R, Remane Y, Bachmann A, Lindner T, Weidhase L, Petros S, Fricke S, Vucinic V, Al Ali H, Niederwieser D. Bendamustine and prednisone in combination with bortezomib (BPV) in the treatment of patients with relapsed or refractory multiple myeloma and light chain-induced renal failure. Journal of Cancer Research and Clinical Oncology. 139 (2013), 11, S. 1937–46. DOI dx.doi.org/10.1007/s00432-013-1513-2
Ramsbeck D., Buchholz M., Koch B., Böhme S., Hoffmann T., Demuth H-U, Heiser U. Structure-activity relationships of benzimidazole-based glutaminyl cyclase inhibitors featuring a heteroaryl scaffold. Journal of Medicinal Chemistry.56 (2013), 17, S. 6613–25. DOI dx.doi.org/10.1021/jm4001709
Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J. RNAsnp: Efficient detection of local RNA secondary structure changes induced by SNPs. Human mutation 34 (2013), Nr. 4, S. 546–556. DOI dx.doi.org/10.1002/humu.22273
Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J. The RNAsnp web server: predicting SNP effects on local RNA secondary structure. Nucleic Acids Research 41 (2013), Nr. W1, S. W475–W479. DOI dx.doi.org/10.1093/nar/gkt291
Sack U, Barnett D, Demirel GY, Fossat C, Fricke S, Kafassi N, Nebe T, Psarra K, Steinmann J, Lambert C. Accreditation of flow cytometry in Europe. Cytometry B Clinical Cytometry. 84 B (2013), 3, S. 135–42. DOI dx.doi.org/10.1002/cyto.b.21079
Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR. Role of different replacement fluids during extracorporeal treatment in a pig model of sepsis. Therapeutic Apheresis and Dialysis. 17 (2013), 1, S. 84–92. DOI dx.doi.org/10.1111/j.1744-9987.2012.01103.x
Schreiber R, Luong N, Fan Z, Kuzyk A, Nickels PC, Zhang T, Smith DM, Yurke B, Kuang W, Govorov AO, Liedl T. Chiral plasmonic DNA nanostructures with switchable circular dichroism. Nature Communations. 4 (2013), 2948. DOI dx.doi.org/10.1038/ncomms3948
Smith D, Schüller V, Engst C, Rädler J, Liedl T. Nucleic acid nanostructures for biomedical applications. Nanomedicine. 8 (2013), 1, S. 105–21. DOI dx.doi.org/10.2217/nnm.12.184
Stolzing A, Haendeler J. Aging-mechanisms, models, and translation. Zeitschrift für Gerontologie und Geriatrie. 46 (2013), 7, S. 612. DOI dx.doi.org/10.1007/s00391-013-0528-2
Sun N, Hartmann R, Lecher J, Stoldt M, Funke SA, Gremer L, Ludwig HH, Demuth HU, Kleinschmidt M, Willbold D. Structural analysis of the pyroglutamate-modified isoform of the Alzheimer‘s disease-related amyloid-β using NMR spectroscopy. J Pept Sci. 2012 Nov;18(11):691-5. DOI dx.doi.org/10.1002/psc.2456 Epub 2012 Sep 24
Tessema B, Beer J, Merker M, Emmrich F, Sack U, Rodloff AC, Niemann S. Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia. BMC Infectious Diseases. 13 (2013), 131. DOI dx.doi.org/10.1186/1471-2334-13-131
Wachsmuth M, Findeiß S, Weissheimer N, Stadler PF, Mörl M. De novo design of a synthetic riboswitch that regulates transcription termination. Nucleic Acids Research 41 (2013), Nr. 4, S. 2541–2551. DOI dx.doi.org/10.1093/nar/gks1330
Wagner DC, Scheibe J, Glocke I, Weise G, Deten A, Boltze J, Kranz A. Object-based analysis of astroglial reaction and astrocyte subtype morphology after ischemic brain injury. Acta Neurobiologiae Experimentals. 73 (2013), 1, S. 79–87.
Will S, Siebauer MF, Heyne S, Engelhardt J, Stadler PF, Reiche K, Backofen R. LocARNAscan: incorporating thermodynamic stability in sequence and structure-based RNA homology search. Algorithms for Molecular Biology. 8 (2013), 1, 14. DOI dx.doi.org/10.1186/1748-7188-8-14

Publikationen 2012

Arnold A, Naaldijk YM, Fabian C, Wirth H, Binder H, Nikkhah G, Armstrong L, Stolzing A. Reprogramming of Human Huntington Fibroblasts Using mRNA. ISRN Cell Biology, Volume 2012 (2012), Article ID 124878, 12 pages. DOI dx.doi.org/10.5402/2012/124878 Article
Averill MM, Kerkhoff C, Bornfeldt KE. S100A8 and S100A9 in cardiovascular biology and disease. Arterioscler Thromb Vasc Biol. 32 (2012), 2, S. 223-9. DOI dx.doi.org/10.1161/ATVBAHA.111.236927
Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, Saliba F, Sauerbruch T, Klammt S, Ockenga J, Pares A, Wendon J, Brünnler T, Kramer L, Mathurin P, Mata MD, Gasbarrini A, Müllhaupt B, Wilmer A, Laleman W, Eefsen M, Sen S, Zipprich A, Tenorio T, Pavesi M, Schmidt HH, Mitzner S, Williams R, Arroyo V. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: The RELIEF trial. Hepatology. 2012. DOI dx.doi.org/10.1002/hep.26185 [Epub ahead of print]
Beer S, Gomez T, Dallinger D, Momber I, Marnay C, Stadler M, Lai J. An economic analysis of used electric vehicle batteries integrated into commercial building microgrids. IEEE transactions on smart grid 3 (2012), 1, S.517-525. DOI dx.doi.org/10.1109/TSG.2011.2163091
Boltze J, Kleinschnitz C, Reymann KG, Reiser G, Wagner DC, Kranz A, Michalski D; the meeting contributors. Neurovascular pathophysiology in cerebral ischemia, dementia and the ageing brain - current trends in basic, translational and clinical research. Exp Transl Stroke Med. 4 (2012), 1:14. DOI dx.doi.org/10.1186/2040-7378-4-14
Boltze J, Reich DM, Hau S, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Kamprad M, Stahl T. Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo. Cell Transplant. 21 (2012), 4, S. 723-737. DOI dx.doi.org/10.3727/096368911X586783
Boltze J, Schmidt UR, Reich DM, Kranz A, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Förschler A, Schäbitz WR. Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats. Cell Transplant. 21 (2012), 6, S. 1199-211. DOI dx.doi.org/10.3727/096368911X589609
Burkhardt J, Kirsten H, Holland H, Krupp W, Ligges C, Quente E, Boltze J, Ahnert P, Wilcke A. Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort. Psychiatric Genetics. 22 (2012), 6, S. 307-308. DOI dx.doi.org/10.1097/YPG.0b013e328353aeae
Burkhardt J, Kirsten H, Wolfram G, Quente E, Ahnert P. Differential allelic expression of IL13 and CSF2 genes associated with asthma. Genetics and molecular biology, 35(2012), 3, S. 567-574. DOI dx.doi.org/10.1590/S1415-47572012005000055
Colley H, McArthur SL, Stolzing A, Scutt A. Culture on fibrin matrices maintains the colony-forming capacity and osteoblastic differentiation of mesenchymal stem cells. Biomed Mater. 7 (2012), 4:045015. DOI dx.doi.org/10.1088/1748-6041/7/4/045015
De Filette M, Ulbert S, Diamond M, Sanders NN. Recent progress in West Nile virus diagnosis and vaccination. Vet Res.43 (2012), 1, S. 16. DOI dx.doi.org/10.1186/1297-9716-43-16
Engelhardt J, Stadler PF. Hidden treasures in unspliced EST data. Theory in Biosciences 131 (2012), 1, S.49-57. DOI dx.doi.org/10.1007/s12064-012-0151-6
Fricke S, Fricke C, Oelkrug C, Blatz R, Schönfelder U, Niederwieser D, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR for the detection and characterisation of Aspergillus species. Mycoses. 55 (2012), 5, S. 416-25. DOI dx.doi.org/10.1111/j.1439-0507.2011.02161.x
Fricke S, Rothe K, Hilger N, Ackermann M, Oelkrug C, Fricke C, Schönfelder U, Niederwieser D, Emmrich F, Sack U. Allogeneic bone marrow grafts with high levels of CD4(+) CD25(+) FoxP3(+) T cells can lead to engraftment failure. Cytometry A. 81 (2012), 6, S. 476-88. DOI dx.doi.org/10.1002/cyto.a.22061
Fueldner C, Mittag A, Knauer J, Biskop M, Hepp P, Scholz R, Wagner U, Sack U, Emmrich F, Tárnok A, Lehmann J. Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry. Arthritis Res Ther. 14 (2012), 1:R8. DOI dx.doi.org/10.1186/ar3682
Fuellen G, Dengjel J, Hoeflich A, Hoeijemakers J, Kestler HA, Kowald A, Priebe S, Rebholz-Schuhmann D, Schmeck B, Schmitz U, Stolzing A, Sühnel J, Wuttke D, Vera J. Systems Biology and Bioinformatics in Aging Research: A Workshop Report. Rejuvenation Res. 15 (2012), 6, S. 631 -641. DOI dx.doi.org/10.1089/rej.2012.1360
Hellmuth M, Ostermeier L, Stadler PF. A survey on hypergraph products. Mathematics in Computer Science 6 (2012), 1, S.1-32. DOI dx.doi.org/10.1007/s11786-012-0109-6
Hellmuth M, Ostermeier L, Stadler PF. Diagonalized Cartesian products of S-prime graphs are S-prime. Discrete mathematics 312 (2012), 1, S.74-80. DOI dx.doi.org/10.1016/j.disc.2011.03.033
Hertel J, Bartschat S, Wintsche A, Otto C, Stadler PF. Evolution of the let-7 microRNA Family. RNA biology 9 (2012), 3, S.231-241. DOI dx.doi.org/10.4161/rna.9.3.18974
Hinz D, Bauer M, Röder S, Olek S, Huehn J, Sack U, Borte M, Simon JC, Lehmann I, Herberth G; for the LINA study group. Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year. Allergy. 67 (2012), 3, S. 380 - 389. DOI dx.doi.org/10.1111/j.1398-9995.2011.02767.x
Hinze A, Stolzing A. Microglia differentiation using a culture system for the expansion of mice non-adherent bone marrow stem cells. J Inflamm (Lond). 9 (2012), 1:12. DOI dx.doi.org/10.1186/1476-9255-9-12
Hofacker IL, Reidys CM, Stadler PF. Symmetric circular matchings and RNA folding. Discrete mathematics 312 (2012), 1, S.100-112. DOI dx.doi.org/10.1016/j.disc.2011.06.004
Holland H, Ahnert P, Koschny R, Kirsten H, Bauer M, Schober R, Meixensberger J, Fritzsch D, Krupp W. Detection of novel genomic aberrations in anaplastic astrocytomas by GTG-banding, SKY, locusspecific FISH, and high density SNP-array. Pathology, research and practice, 208 (2012), 6, S. 325-330. DOI dx.doi.org/10.1016/j.prp.2012.03.010
Johnson AA, Akman K, Calimport SR, Wuttke D, Stolzing A, de Magalhães JP. The role of DNA methylation in aging, rejuvenation, and age-related disease. Rejuvenation Res. 15 (2012), 5, S. 483-94. DOI dx.doi.org/10.1089/rej.2012.1324
Jühling F, Pütz J, Bernt M, Donath A, Middendorf M, Florentz C, Stadler PF. Improved systematic tRNA gene annotation allows new insights into the evolution of mitochondrial tRNA structures and into the mechanisms of mitochondrial genome rearrangements. Nucleic Acids Research 40 (2012), 7, S.2833-2845. DOI dx.doi.org/10.1093/nar/gkr1131
Jühling F, Putz J, Florentz C, Stadler PF. Armless mitochondrial tRNAs in enoplea (nematoda). RNA biology 9 (2012), 9, S.1161-1166. DOI dx.doi.org/10.4161/rna.21630
Kerkhoff C, Voss A, Scholzen TE, Averill MM, Zänker KS, Bornfeldt KE. Novel insights into the role of S100A8/A9 in skin biology. Exp Dermatol. 21 (2012), 11, S. 822 - 6. DOI dx.doi.org/10.1111/j.1600-0625.2012.01571.x
Kielstein JT, Beutel G, Fleig S, Steinhoff J, Meyer TN, Hafer C, Kuhlmann U, Bramstedt J, Panzer U, Vischedyk M, Busch V, Ries W, Mitzner S, Mees S, Stracke S, Nürnberger J, Gerke P, Wiesner M, Sucke B, Abu-Tair M, Kribben A, Klause N, Schindler R, Merkel F, Schnatter S, Dorresteijn EM, Samuelsson O, Brunkhorst R; Collaborators of the DGfN STEC-HUS registry. Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome: an analysis of the German STEC-HUS registry. Nephrol Dial Transplant. 27 (2012), 10, S. 3807-15. DOI dx.doi.org/10.1093/ndt/gfs394
Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatric Genetics. 22 (2012), 4, S. 216-217. DOI dx.doi.org/10.1097/YPG.0b013e32834c0c97
Klammt S, Wojak HJ, Mitzner A, Koball S, Rychly J, Reisinger EC, Mitzner S. Albumin-binding capacity (ABiC) is reduced in patients with chronic kidney disease along with an accumulation of protein-bound uraemic toxins. Nephrol Dial Transplant. 27 (2012), 6, S. 2377-83. DOI dx.doi.org/10.1093/ndt/gfr616
Klemm K, Mehta A, Stadler PF. Landscape encodings enhance optimization. PLoS one. Online journal 7 (2012), 4, Art. E34780. DOI dx.doi.org/10.1371/journal.pone.0034780
Klionsky DJ and 1269 others. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8 (2012), 4, S. 445 - 544. DOI dx.doi.org/10.4161/auto.19496
Koch H, Graneist C, Emmrich F, Till H, Metzger R, Aupperle H, Schierle K, Sack U, Boldt A. Xenogenic esophagus scaffolds fixed with several agents: comparative in vivo study of rejection and inflammation. J Biomed Biotechnol. 2012; 2012:948320. DOI dx.doi.org/10.1155/2012/948320
Kuhlmeier D, Sandetskaya N, Allelein S. Application of nanotechnology in miniaturized systems and its use in medical and food analysis. Recent Pat Food Nutr Agric. 4 (2012), 3, S. 187-99. DOI dx.doi.org/10.2174/2212798411204030187
Lange F, Sack U. Gelenkentzündungen : Modellsysteme für die Arthritisforschung. GIT Spezial BIOforum 1/2012, S. 28-30. GIT Labor-Fachzeitschrift 56 (2012), 6, S. 459-461. Artikel
Langenberger D, Pundhir S, Ekstrom CT, Stadler PF, Hoffmann S, Gorodkin J. deepBlockAlign: A tool for aligning RNA-seq profiles of read block patterns. Bioinformatics 28 (2012), 1, S.17-24. DOI dx.doi.org/10.1093/bioinformatics/btr598
Leichsenring A, Lange F. Tiermodelle in der präklinischen Forschung. GIT Labor-Fachzeitschrift 56 (2012), 12, S. 848–849. Artikel
Maletzki C, Bodammer P, Breitrück A, Kerkhoff C. S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma. Hepat Mon. 2012, 12 (10 HCC):e7240. DOI dx.doi.org/10.5812/hepatmon.7240
Michalski D, Heindl M, Kacza J, Laignel F, Küppers-Tiedt L, Schneider D, Grosche J, Boltze J, Löhr M, Hobohm C, Härtig W. Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation. Eur J Histochem. 2012, 56(2):e14. DOI dx.doi.org/10.4081/ejh.2012.14
Möller K, Stahl T, Boltze J, Wagner DC. Isolation of inflammatory cells from rat brain tissue after stroke. Exp Transl Stroke Med. 4 (2012), 1:20. DOI dx.doi.org/10.1186/2040-7378-4-20
Naaldijk Y, Staude M, Fedorova V, Stolzing A. Effect of different freezing rates during cryopreservation of rat mesenchymal stem cells using combinations of hydroxyethyl starch and dimethylsulfoxide. BMC Biotechnol. (2012) 12:49. DOI dx.doi.org/10.1186/1472-6750-12-49
Ostermeier L, Hellmuth M, Stadler PF. The Cartesian product of hypergraphs. Journal of Graph Theory 70 (2012), 2, S.180-196. DOI dx.doi.org/10.1002/jgt.20609
Otto C, Reiche K, Hackermüller J. Detection of differentially expressed segments in tiling array data. In: Bioinformatics 28 (2012), 11, S.1471-1479. DOI dx.doi.org/10.1093/bioinformatics/bts142
Otto C, Stadler PF, Hoffmann S. Fast and sensitive mapping of bisulfite-treated sequencing data. Bioinformatics 28 (2012), 13, S.1698-1704. DOI dx.doi.org/10.1093/bioinformatics/bts254
Pohler P, Lehmann J, Veneruso V, Tomm J, v. Bergen M, Lambrecht B, Kohn B, Weingart C, Müller TH, Seltsam A. Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model. Transfusion. 52 (2012), 11, S. 2414-26. DOI dx.doi.org/10.1111/j.1537-2995.2012.03583.x
Polchow B, Kebbel K, Schmiedeknecht G, Reichardt A, Henrich W, Hetzer R, Lueders C. Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks. J Transl Med. 2012; 10:98. DOI dx.doi.org/10.1186/1479-5876-10-98
Pösel C, Möller K, Fröhlich W, Schulz I, Boltze J, Wagner DC. Density gradient centrifugation compromises bone marrow mononuclear cell yield. PLoS One. 7 (2012), 12:e50293. DOI dx.doi.org/10.1371/journal.pone.0050293
Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR. Plasma separation by centrifugation and subsequent plasma filtration: impact on survival in a pig model of sepsis. Ther Apher Dial. 16 (2012), 3, S. 205-12. DOI dx.doi.org/10.1111/j.1744-9987.2011.01055.x
Sauer M, Haubner C, Mencke T, Nöldge-Schomburg G, Mitzner S, Altrichter J, Stange J. Impaired cell functions of hepatocytes incubated with plasma of septic patients. Inflamm Res. 61 (2012), 6, S. 609-16. DOI dx.doi.org/10.1007/s00011-012-0451-9
Schmidtke C, Findeiß S, Sharma CM, Kuhfuß J, Hoffmann S, Vogel J, Stadler PF, Bonas U. Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions. Nucleic Acids Research 40 (2012), 5, S.2020-2031. DOI dx.doi.org/10.1093/nar/gkr904
Scholbach J, Schulz A, Westphal F, Egger D, Wege AK, Patties I, Köberle M, Sack U, Lange F. Comparison of hematopoietic stem cells derived from fresh and cryopreserved whole cord blood in the generation of humanized mice. PLoS One. 7 (2012), 10:e46772. DOI dx.doi.org/10.1371/journal.pone.0046772
Stolzing A, Bauer E, Scutt A. Suspension cultures of bonemarrow-derived mesenchymal stem cells: effects of donor age and glucose level. Stem Cells Dev. 21 (2012), 14, S. 2718-23. DOI dx.doi.org/10.1089/scd.2011.0406
Stolzing A, Naaldijk Y, Fedorova V, Sethe S. Hydroxyethylstarch in cryopreservation - mechanisms, benefits and problems. Transfus Apher Sci. 46 (2012), 2, S. 137-47. DOI dx.doi.org/10.1016/j.transci.2012.01.007
Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B, Klaesner B, Zhu C, Schwarzmaier S, Meissner L, Mamrak U, Engel DC, Drzezga A, Patel RP, Blomgren K, Barthel H, Boltze J, Kuebler WM, Plesnila N. Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles. Circ Res. 110 (2012), 5, S. 727-38. DOI dx.doi.org/10.1161/CIRCRESAHA.111.253419
Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. Analysis of gene mutations associated with isoniazid, rifampicin and ethambutol resistance among Mycobacterium tuberculosis isolates from Ethiopia. BMC Infect Dis. 12 (2012) :37. DOi dx.doi.org/10.1186/1471-2334-12-37
Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. First- and second-line anti-tuberculosis drug resistance in Northwest Ethiopia. Int J Tuberc Lung Dis. 16 (2012), 6 S. 805-11. DOI dx.doi.org/10.5588/ijtld.11.0522
Tippmann SC, Ivanek R, Gaidatzis D, Scholer A, Hoerner L, Nimwegen E. van, Stadler PF, Stadler MB, Schubeler D. Chromatin measurements reveal contributions of synthesis and decay to steady-state mRNA levels. Molecular systems biology 8 (2012), Art.593. DOI dx.doi.org/10.1038/msb.2012.23
Voss A, Bode G, Kerkhoff C. Double-stranded RNA induces IL-8 and MCP-1 gene expression via TLR3 in HaCaTkeratinocytes. Inflamm Allergy Drug Targets. 11 (2012), 5, S. 397-405.
Voss A, Gescher K, Hensel A, Nacken W, Zänker KS, Kerkhoff C. Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor. FEBS Lett. 586 (2012), 2, S. 196-203. DOI dx.doi.org/10.1016/j.febslet.2011.12.022
Wagner DC, Bojko M, Peters M, Lorenz M, Voigt C, Kaminski A, Hasenclever D, Scholz M, Kranz A, Weise G, Boltze J. Impact of age on the efficacy of bone marrow mononuclear cell transplantation in experimental stroke. Exp Transl Stroke Med. 24(2012), 1:17. DOI dx.doi.org/10.1186/2040-7378-4-17
Wagner DC, Deten A, Härtig W, Boltze J, Kranz A. Changes in T2 relaxation time after stroke reflect clearing processes. Neuroimage.61 (2012), 4, S. 780-5. DOi dx.doi.org/10.1016/j.neuroimage.2012.04.023
Weise G, Stoll G. Magnetic resonance imaging of blood brain/nerve barrier dysfunction and leukocyte infiltration: closely related or discordant? Front Neurol. 2012; 3:178. DOi dx.doi.org/10.3389/fneur.2012.00178
Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H. Imaging genetics of FOXP2 in dyslexia. European Journal of Human Genetics, 20 (2012), 2, S. 224-229. DOI dx.doi.org/10.1038/ejhg.2011.160
Will S, Joshi T, Hofacker IL, Stadler PF, Backofen R. LocARNA-P: Accurate boundary prediction and improved detection of structural RNAs. RNA 18 (2012), 5, S.900-914. DOI dx.doi.org/10.1261/rna.029041.111
Wuttig D, Zastrow S, Füssel S, Toma MI, Meinhardt M, Kalman K, Junker K, Sanjmyatav J, Boll K, Hackermüller J, Rolle A, Grimm M-O, Wirth MP. CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases. International journal of cancer 131 (2012), 5, S.E693-E704. DOI dx.doi.org/10.1002/ijc.27419

Publikationen 2011

Boltze J, Kranz A, Wagner DC, Reymann K, Reiser G, Hess DC. Recent advances in basic and translational stroke research. Expert Rev Neurother. 2011 Feb;11(2):199-202.
Boltze J, Nitzsche B, Geiger KD, Schoon HA. Histopathological investigation of different MCAO modalities and impact of autologous bone marrow mononuclear cell administration in an Ovine stroke model. Translational Stroke Research 2 (2011), 3, S.279-293. DOI dx.doi.org/10.1007/s12975-011-0101-5
Boltze J, Reich DM, Hau S, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Kamprad M, Stahl T. Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo. Cell Transplant. 2011 Sep 16. DOI dx.doi.org/10.3727/096368911X586783 [Epub ahead of print]
Boltze J, Schmidt UR, Reich DM, Kranz A, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Förschler A, Schäbitz WR. Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats. Cell Transplant. 2011 Dec 13. DOI dx.doi.org/10.3727/096368911X589609 [Epub ahead of print]
Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, Gingeras TR, Mattick JS. The reality of pervasive transcription. PLoS Biol. 9 (2011), 7, e1000625; discussion e1001102. DOI dx.doi.org/10.1371/journal.pbio.1000625
Efimenko A, Starostina E, Kalinina N, Stolzing A. (2011) Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. J Transl Med. Jan 18;9(1):10. DOI dx.doi.org/10.1186/1479-5876-9-10 Article
Eggenhofer F, Tafer H, Stadler PF, Hofacker IL. RNApredator : fast accessibility-based prediction of sRNA targets. Nucleic Acids Res. 39 (2011), Supl. 2, W149-54. DOI dx.doi.org/10.1093/nar/gkr467
Fangmann J, Kathrin Al-Ali H, Sack U, Kamprad M, Tautenhahn HM, Faber S, Hauss J, Niederwieser D, Lindner T, Bachmann A. Kidney transplant from the same donor without maintenance immunosuppression after previous hematopoietic stem cell transplant. Am J Transplant. 11 (2011), 1, S. 156 - 62. DOI dx.doi.org/10.1111/j.1600-6143.2010.03352.x
Fasold M, Langenberger D, Binder H, Stadler PF, Hoffmann S. DARIO: a ncRNA detection and analysis tool for next-generation sequencing experiments. Nucleic Acids Res. 39 (2011), Supl. 2, S. W112-7. DOI dx.doi.org/10.1093/nar/gkr357
Findeiss S, Engelhardt J, Prohaska SJ, Stadler PF. Protein-coding structured RNAs: A computational survey of conserved RNA secondary structures overlapping coding regions in drosophilids. Biochimie. 93 (2011), 11, S. 2019-23. DOI dx.doi.org/10.1016/j.biochi.2011.07.023
Findeiss S, Langenberger D, Stadler PF, Hoffmann S. Traces of post-transcriptional RNA modifications in deep sequencing data. Biol Chem. 2392 (2011), 4, S. 305-13. DOI dx.doi.org/10.1515/bc.2011.043
Fricke S, Fricke C, Oelkrug C, Blatz R, Schönfelder U, Niederwieser D, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR for the detection and characterisation of Aspergillus species. Mycoses. 2011 Dec 11. DOI dx.doi.org/10.1111/j.1439-0507.2011.02161.x [Epub ahead of print]
Grey D, Sack U, Scholz M, Knaack H, Fricke S, Oppel C, Luderer D, Fangmann J, Emmrich F, Kamprad M. Increased CD64 expression on polymorphonuclear neutrophils indicates infectious complications following solid organ transplantation. Cytometry A. 79 (2011), 6, S. 446 - 60. DOI dx.doi.org/10.1002/cyto.a.21049
Hinze A, Stolzing A. (2011) Differentiation of mouse bone marrow derived stem cells toward microglia. BMC Cell Biology. Aug 19;12(1):35. DOI dx.doi.org/10.1186/1471-2121-12-35 Article
Holland H, Livrea M, Ahnert P, Koschny R, Kirsten H, Meixensberger J, Bauer M, Schober R, Fritzsch D, Krupp W. Intracranial hemangiopericytoma: Case study with cytogenetics and genome wide SNP-A analysis. Pathol Res Pract. 2011 Feb 7. [Epub ahead of print]
Jühling F, Pütz J, Bernt M, Donath A, Middendorf M, Florentz C, Stadler PF. Improved systematic tRNA gene annotation allows new insights into the evolution of mitochondrial tRNA structures and into the mechanisms of mitochondrial genome rearrangements. Nucleic Acids Res. 2011 Dec 1. [Epub ahead of print] DOI dx.doi.org/10.1093/nar/gkr1131
Kehr S, Bartschat S, Stadler PF, Tafer H. PLEXY : efficient target prediction for box C/D snoRNAs. Bioinformatics. 27 (2011), 2, S. 279-80. DOI dx.doi.org/10.1093/bioinformatics/btq642
Kim M, Garant KA, Zur Nieden N, Alain T, Loken SD, Urbanski SJ, Forsyth PA, Rancourt D, Lee PW, Johnston RN. Attenuated reovirus displays oncolysis with reduced host toxicity. The British journal of cancer. 104 (2011), 2, S. 290 - 299. DOI dx.doi.org/10.1038/sj.bjc.6606053
Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatr Genet. 2011 Sep 20. DOI dx.doi.org/10.1097/YPG.0b013e32834c0c97 [Epub ahead of print].
Knauer J, Krupka I, Fueldner C, Lehmann J, Straubinger RK. Evaluation of the preventive capacities of a topically applied azithromycin formulation against Lyme borreliosis in a murine model. J Antimicrob Chemother. 66 (2011), 12, S. 2814 - 2822. DOI dx.doi.org/10.1093/jac/dkr371
Krakauer DC, Collins JP, Erwin D, Flack JC, Fontana W, Laubichler MD, Prohaska SJ, West GB, Stadler PF. The challenges and scope of theoretical biology. J Theor Biol. 276 (2011), 1, S. 269-76. DOI dx.doi.org/10.1016/j.jtbi.2011.01.051
Lechner M, Findeiss S, Steiner L, Marz M, Stadler PF, Prohaska SJ. Proteinortho : detection of (co-)orthologs in large-scale analysis. BMC Bioinformatics. 12 (2011), 124, 9 S. DOI dx.doi.org/10.1186/1471-2105-12-124
Marz M, Stadler PF. RNA interactions. Adv Exp Med Biol. 722 (2011), S. 20-38. DOI dx.doi.org/10.1007/978-1-4614-0332-6_2
Menzel P, Stadler PF, Gorodkin J. MaxAlike : maximum likelihood-based sequence reconstruction with application to improved primer design for unknown sequences. Bioinformatics. 27 (2011), 3, S. 317-25. DOI dx.doi.org/10.1093/bioinformatics/btq651
Michalski D, Pelz J, Weise C, Kacza J, Boltze J, Grosche J, Kamprad M, Schneider D, Hobohm C, Härtig W. Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke. Exp Transl Stroke Med. 3 (2011), 5, 9 S. DOI dx.doi.org/10.1186/2040-7378-3-5
Mocker K, Holland H, Ahnert P, Schober R, Bauer M, Kirsten H, Koschny R, Meixensberger J, Krupp W. Multiple meningioma with different grades of malignancy: case report with genetic analysis applying single-nucleotide polymorphism array and classical cytogenetics. Pathol Res Pract. 2011 Jan 15;207(1):67-72.
Oschatz C, Maas C, Lecher B, Jansen T, Björkqvist J, Tradler T, Sedlmeier R, Burfeind P, Cichon S, Hammerschmidt S, Müller-Esterl W, Wuillemin WA, Nilsson G, Renné T. Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity. 34 (2011), 2, S. 258-68. DOI dx.doi.org/10.1016/j.immuni.2011.02.008
Otto C, Hoffmann S, Gorodkin J, Stadler PF. Fast local fragment chaining using sum-of-pair gap costs. Algorithms Mol Biol. 6 (2011), 4, 8 S. DOI dx.doi.org/10.1186/1748-7188-6-4
Paulsen K, Tauber S, Timm J, Goelz N, Dumrese C, Stolzing A, Hass R, Ullrich O. (2011) The cannabinoid receptors agonist WIN55212-2 inhibits macrophageal differentiation and alters expression and phosphorylation of cell cycle control proteins. Cell Commun Signal. Dec 28;9(1):33.
Perseke M, Hetmank J, Bernt M, Stadler PF, Schlegel M, Bernhard D. The enigmatic mitochondrial genome of Rhabdopleura compacta (Pterobranchia) reveals insights into selection of an efficient tRNA system and supports monophyly of Ambulacraria. BMC Evol Biol. 11 (2011), 134, 12 S. DOI dx.doi.org/10.1186/1471-2148-11-134
Raincrow JD, Dewar K, Stocsits C, Prohaska SJ, Amemiya CT, Stadler PF, Chiu CH. Hox clusters of the bichir (Actinopterygii, Polypterus senegalus) highlight unique patterns of sequence evolution in gnathostome phylogeny. J Exp Zool B Mol Dev Evol. 16 (2011), 6, S. 451-64. DOI dx.doi.org/10.1002/jez.b.21420
Reidys CM, Huang FW, Andersen JE, Penner RC, Stadler PF, Nebel ME. Topology and prediction of RNA pseudoknots. Bioinformatics. 27 (2011), 8, S. 1076-85. DOI dx.doi.org/10.1093/bioinformatics/btr090
Riegelsberger UM, Deten A, Pösel C, Zille M, Kranz A, Boltze J, Wagner DC. Intravenous human umbilical cord blood transplantation for stroke: impact on infarct volume and caspase-3-dependent cell death in spontaneously hypertensive rats. Exp Neurol. 2011 Jan;227(1):218-23. Epub 2010 Nov 16.
Roesler U, Szabo I, Matthies C, Albrecht K, Leffler M, Scherer K, Nöckler K, Lehmann J, Methner U, Hensel A, Truyen U. Comparing validation of four ELISA-systems for detection of Salmonella derby- and Salmonella infantis-infected pigs. Berl Munch Tierarztl Wochenschr. 124 (2011), 7-8, S. 265-71. DOI dx.doi.org/10.2376/0005-9366-124-265
Rose D, Hiller M, Schutt K, Hackermüller J, Backofen R, Stadler PF. Computational discovery of human coding and non-coding transcripts with conserved splice sites. Bioinformatics. 27 (2011), 14, S. 1894-900. DOI dx.doi.org/10.1093/bioinformatics/btr314
Rupf S, Idlibi AN, Marrawi FA, Hannig M, Schubert A, von Mueller L, Spitzer W, Holtmann H, Lehmann A, Rueppell A, Schindler A. Removing biofilms from microstructured titanium ex vivo: a novel approach using atmospheric plasma technology. PLoS One.6 (2011), 10, e25893, 9 S. DOI dx.doi.org/10.1371/journal.pone.0025893
Schneeweiss A, Chabierski S, Salomo M, Delaroque N, Al-Robaiy S, Grunwald T, Bürki K, Liebert UG, Ulbert S. A DNA vaccine encoding the E protein of West Nile Virus is protective and can be boosted by recombinant domain DIII. Vaccine, 29 (2011), S. 6352-6357.
Schubert K, Polte T, Bönisch U, Schader S, Holtappels R, Hildebrandt G, Lehmann J, Simon JC, Anderegg U, Saalbach A. Thy-1 (CD90) regulates the extravasation of leukocytes during inflammation. Eur J Immunol. 41 (2011), 3, S. 645 - 656. DOI dx.doi.org/10.1002/eji.201041117
Skardelly M, Gaber K, Burdack S, Scheidt F, Hilbig H, Boltze J, Förschler A, Schwarz S, Schwarz J, Meixensberger J, Schuhmann MU. Long-term benefit of human fetal neuronal progenitor cell transplantation in a clinically adapted model after traumatic brain injury. J Neurotrauma. 28 (2011), 3, S. 401-14. DOI dx.doi.org/10.1089/neu.2010.1526
Smith DM, Schüller V, Forthmann C, Schreiber R, Tinnefeld P, Liedl T. A structurally variable hinged tetrahedron framework from DNA origami. J. Nuc. Acid., 2011. DOI dx.doi.org/10.4061/2011/360954
Stolzing A, Colley H, Scutt A. (2011) Effect of age and diabetes on the response of mesenchymal progenitor cells to fibrin matrices. Int J Biomater. 2011; 378034. Epub 2011 Dec 13. DOI dx.doi.org/10.1155/2011/378034 Article
Tafer H, Amman F, Eggenhofer F, Stadler PF, Hofacker IL. Fast accessibility-based prediction of RNA-RNA interactions. Bioinformatics. 27 (2011), 14, S. 1934-40. DOI dx.doi.org/10.1093/bioinformatics/btr281
Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B, Klaesner B, Zhu C, Schwarzmaier S, Meissner L, Mamrak U, Engel DC, Drzezga A, Patel RP, Blomgren K, Barthel H, Boltze J, Kuebler WM, Plesnila N. Inhalation of nitric oxide prevents Ischemic brain damage in experimental stroke by selective dilatation of Collateral Arterioles. Circ Res. 2011 Dec 29. DOI dx.doi.org/10.1161/CIRCRESAHA.111.253419 [Epub ahead of print]
Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. Rate of recovery of Mycobacterium tuberculosis from frozen acid-fast-bacillus smear-positive sputum samples subjected to long-term storage in Northwest Ethiopia. J Clin Microbiol. 49 (2011), 7, S. 2557 - 61. DOI dx.doi.org/10.1128/JCM.00059-11
Tramontano A, Donath A, Bernhart SH, Reiche K, Böhmdorfer G, Stadler PF, Bachmair A. Deletion analysis of the 3' long terminal repeat sequence of plant retrotransposon Tto1 identifies 125 base pairs redundancy as sufficient for first strand transfer. Virology. 412 (2011), 1, 75 - 82. DOI dx.doi.org/10.1016/j.virol.2010.12.059
Ulbert S. West Nile Virus: The Complex Biology of an Emerging Pathogen. Intervirology, 54 (2011), S. 171-184.
Ullrich A, Rohrschneider M, Scheuermann G, Stadler PF, Flamm C. In silico evolution of early metabolism. Artif Life. 17 (2011), 2, S. 87-108. DOI dx.doi.org/10.1162/artl_a_00021
Wagner DC, Riegelsberger UM, Michalk S, Härtig W, Kranz A, Boltze J. Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic. Brain Res. 2011 Mar 24;1381:237-42. Epub 2011 Jan 20.
Washietl S, Findeiss S, Müller SA, Kalkhof S, von Bergen M, Hofacker IL, Stadler PF, Goldman N. RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data. RNA. 17 (2011), 4, S. 578-94. DOI dx.doi.org/10.1261/rna.2536111
Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H. Imaging genetics of FOXP2 in dyslexia. Eur J Hum Genet. 20 (2012), 2, S. 224-9. DOI dx.doi.org/10.1038/ejhg.2011.160
Wuttig D, Zastrow S, Füssel S, Toma MI, Meinhardt M, Kalman K, Junker K, Sanjmyatav J, Boll K, Hackermüller J, Rolle A, Grimm MO, Wirth MP. CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases. Int J Cancer. 2011 Dec 31. DOI dx.doi.org/10.1002/ijc.27419 [Epub ahead of print]
zu Siederdissen CH, Bernhart SH, Stadler PF, Hofacker IL. A folding algorithm for extended RNA secondary structures. Bioinformatics. 27 (2011), 13, S. i129-36. DOI dx.doi.org/10.1093/bioinformatics/btr220

Publikationen 2010

Al-Robaiy S, Dihazi H, Kacza J, Seeger J, Schiller J, Huster D, Knauer J, Straubinger RK. Metamorphosis of Borrelia burgdorferi organisms – RNA, lipid and protein composition in context with the spirochetes’ shape. Journal of Basic Microbiology. 50 (2010), Sup. 1, S. 5–17.
Amemiya CT, Powers TP, Prohaska SJ, Grimwood J, Schmutz J, Dickson M, Miyake T, Schoenborn MA, Myers R, Ruddle FH, Stadler PF. Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome. Proceedings of the National Academy of Sciences of the United States of America. 107 (2010), 8, S. 3622–3627.
Arnold C, Stadler PF. Polynomial algorithms for the Maximal Pairing Problem: efficient phylogenetic targeting on arbitrary trees. Algorithms for molecular biology. 5 (2010), 25, 10 S. DOI dx.doi.org/10.1186/1748-7188-5-25
Bermudez-Santana C, Attolini CSO, Kirsten T, Engelhardt J, Prohaska SJ, Steigele S, Stadler PF. Genomic organization of eukaryotic tRNAs. BMC genomics. 11 (2010), 270, 14 S. DOI dx.doi.org/10.1186/1471-2164-11-270
Boria I, Gruber A, Tanzer A, Bernhart SH, Lorenz R, Müller MM, Hofacker IL, Stadler PF. Nematode sbRNAs: homologs of vertebrate Y RNAs. Journal of molecular evolution. 70 (2010), 4, S. 346–358.
Chung NP, Breun SK, Bashirova A, Baumann JG, Martin TD, Karamchandani JM, Rausch JW, Le Grice SF, Wu L, Carrington M, Kewalramani VN. HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN). J Biol Chem. 285 (2010), 3, S. 2100–2112.
Dienelt A, zur Nieden NI. Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation. Stem Cells Dev. 2010 Nov 30 [Epub ahead of print]. DOI dx.doi.org/10.1089/scd.2010.025
Fasold M, Stadler PF, Binder H. G-stack modulated probe intensities on expression arrays – sequence corrections and signal calibration. BMC bioinformatics. 11 (2010), 207, 24 S. DOI dx.doi.org/10.1186/1471-2105-11-207
Findeiß S, Schmidtke C, Stadler PF, Bonas U. A novel family of plasmid-transferred anti-sense ncRNAs. RNA biology. 7 (2010), 2, S. 120–124. DOI dx.doi.org/10.4161/rna.7.2.11184
Fricke S, Fricke C, Oelkrug C, Hilger N, Schönfelder U, Kamprad M, Lehmann J, Boltze J, Emmrich F, Sack U. Characterization of murine non-adherent bone marrow cells leading to recovery of endogenous hematopoiesis. Cell Mol Life Sci. 67 (2010), 23, S. 4095–4106.
Fricke S, Fricke C, Schimmelpfennig C, Oelkrug C, Schönfelder U, Blatz R, Zilch C, Faber S, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR assay for the differentiation of Candida species. J Appl Microbiol. 109 (2010), 4, S 1150–1158.
Gessner C, Rechner B, Hammerschmidt S, Kuhn H, Hoheisel G, Sack U, Ruschpler P, Wirtz H. Angiogenic markers in breath condensate identify non-small cell lung cancer. Lung Cancer, 68 (2010), 2, S. 177–184.
Hemdan NY, Birkenmeier G, Wichmann G, Abu El-Saad A, Krieger T, Conrad K, Sack U. Interleukin-17-producing T helper cells in autoimmunity. Autoimmunity Reviews, 9 (2010), 11, S. 785–792.
Hinz D, Simon JC, Maier-Simon C, Milkova L, Röder S, Sack U, Borte M, Lehmann I, Herberth G. Reduced maternal regulatory T cell numbers and increased T helper type 2 cytokine production are associated with elevated levels of immunoglobulin E in cord blood. Clinical and Experimental Allergy. 40 (2010), 3, S. 419–426.
Hofacker I, Flamm C, Heine C, Wolfinger MT, Scheuermann G, Stadler PF. BarMap: RNA folding on dynamic energy landscapes, RNA. 16 (2010), 7, S. 1308–1316.
Huang FWD, Qin J, Reidys CM, Stadler PF. Target prediction and a statistical sampling algorithm for RNA-RNA interaction. Bioinformatics. 26 (2010), 2, S. 175–181.
Kranz A, Wagner DC, Kamprad M, Scholz M, Schmidt UR, Nitzsche F, Aberman Z, Emmrich F, Riegelsberger UM, Boltze J. Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats. Brain Res, 1315 (2010), S. 128–36.
Lehmann J, Stadler PF, Eisenhardt C, Krauss V. Some novel intron positions in conserved Drosophila genes are caused by intron sliding or tandem duplication. BMC evolutionary biology. 10 (2010), 156, 15 S. DOI dx.doi.org/10.1186/1471-2148-10-156
Lenz D, Barten MJ, Hiller S, Tarnok A, Sack U. Regenerative and predictive medicine of cardiovascular disease: the 9th Leipziger Workshop and the 2nd International Workshop on slide based cytometry. Cytom Part A, 64 (2005), 2, S. 110-114.
Lindner I. et al. alpha 2-Macroglobulin Inhibits the Malignant Properties of Astrocytoma Cells by Impeding beta-Catenin Signaling. Cancer Research, v. 70 (2010), no. 1, p. 277–287.
Marz M, Vanzo N, Stadler PF. Temperature-dependent structural variability of RNAs: spliced leader RNAs and their evolutionary history. Journal of bioinformatics and computational biology. 8 (2010), 1, S. 1–17.
Mühle A, Mühle C, Amann K, Dötsch J, Nüsken KD, Boltze J, Schneider H. No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers. Pediatr Nephrol. 25 (2010), 9, S. 1653–61.
Müller M, Lutter D, Püschel AW. Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. J Cell Sci. 123 (2010), Pt 2, S. 286–94.
Perseke M, Bernhard D, Fritzsch G, Brümmer F, Stadler PF, Schlegel M. Mitochondrial genome evolution in Ophiuroidea, Echinoidea, and Holothuroidea: insights in phylogenetic relationships of Echinodermata. Molecular phylogenetics and evolution. 56 (2010), 1, S. 201–211.
Prohaska SJ, Stadler PF, Krakauer DC. Innovation in gene regulation: the case of chromatin computation. Journal of theoretical biology. 265 (2010), 1, S. 27–44.
Riester M, Stadler PF, Klemm K. Reconstruction of pedigrees in clonal plant populations. Theoretical population biology. 78 (2010), 2, S. 109–117.
Rupf S, Lehmann A, Hannig M, Schafer B, Schubert A, Feldmann U, Schindler A. Killing of adherent microbes by a non-thermal atmospheric plasma jet. J Med Microbiol. 59 (2010), Pt 2, S. 206–12.
Schneeweiss A, Buyens K, Giese M, Sanders N, Ulbert S. Synergistic effects between natural histone mixtures and polyethylenimine in non-viral gene delivery in vitro. Int J Pharm. 400 (2010), 1–2, S. 86–95.
Sharma C, Hoffmann S, Darfeuille F, Reignier J, Findeiß S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J. The primary transcriptome of the major human pathogen Helicobacter pylori. Nature. 464 (2010), 7286, S. 250–255.
Stadler BM, Stadler PF. Combinatorial vector fields and the valley structure of fitness landscapes. Journal of mathematical biology. 61 (2010), 6, S. 877–898.
Stolzing A, Sellers D, Llewelyn O, Scutt A. Diabetes induced changes in rat mesenchymal stem cells. Cells Tissues Organs. 191 (2010), 6, S. 453–65.
Tafer H, Kehr S, Hertel J, Hofacker IL, Stadler PF. RNAsnoop : efficient target prediction for H/ACA snoRNAs. Bioinformatics. 26 (2010), 5, S. 610–616.
Taiani JT, Krawetz RJ, zur Nieden NI, Wu YE, Kallos MS, Matyas JR, Rancourt DE. Reduced Differentiation Efficiency of Murine Embryonic Stem Cells in Stirred Suspension Bioreactors. Stem Cell Dev. (2010), 7, S. 989–998.
Tessema B, Biadglegne F, Mulu A, Getachew A, Emmrich F, Sack U. Magnitude and determinants of nonadherence and nonreadiness to highly active antiretroviral therapy among people living with HIV/AIDS in Northwest Ethiopia: a cross-sectional study. AIDS research and therapy, 7 (2010), 2, 8 S. DOI dx.doi.org/10.1186/1742-6405-7-2
Tessema B, Yismaw G, Kassu A, Amsalu A, Mulu A, Emmrich F, Sack U. Seroprevalence of HIV, HBV, HCV and syphilis infections among blood donors at Gondar University Teaching Hospital, Northwest Ethiopia: declining trends over a period of five years. BMC Infectious Diseases, 10 (2010), 111, 7 S. DOI dx.doi.org/10.1186/1471-2334-10-111
Yerebakan C, Klopsch C, Niefeldt S, Zeisig V, Vollmar B, Liebold A, Sandica E, Steinhoff G. Acute and chronic response of the right ventricle to surgically induced pressure and volume overload – an analysis of pressure-volume relations. Interact Cardiovasc Thorac Surg. 10 (2010), 4, S. 519–25.
Yerebakan C, Sandica E, Prietz S, Klopsch C, Ugurlucan M, Kaminski A, Abdija S, Lorenzen B, Boltze J, Nitzsche B, Egger D, Barten M, Furlani D, Ma N, Vollmar B, Liebold A, Steinhoff G. Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload. Cell Transplant, 18 (2009), 8, S. 855-68.
zur Nieden NI, Baumgartner L. Assessing developmental osteotoxicity of chlorides in the embryonic stem cell test. Reprod Toxicol. 30 (2010), 2, S. 277–283.
zur Nieden NI, Davis LA, Rancourt DE. Comparing three novel endpoints for developmental osteotoxicity in the embryonic stem cell test. Toxicol Appl Pharmacol. 247 (2010), 2, S. 91–97.
zur Nieden NI, Davis LA, Rancourt DE. Monolayer cultivation of osteoprogenitors shortens duration of the embryonic stem cell test while reliably predicting developmental osteotoxicity. Toxicology.277 (2010), 1–3, S. 66–73.

Publikationen 2009

Althues H, Pötschke P, Kim G M, Kaskel S. Structure and Mechanical Properties of Transparent ZnO/PBDMA Nanocomposites. J Nanosci Nanotechno, 9 (2009), 4, S. 2739-2745.
Aupperle H, Thielebein J, Kiefer B, März I, Dinges G, Schoon HA, Schubert A. Expression of genes encoding matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in normal and diseased canine mitral valves. J Comp Pathol, 140 (2009), 4, S. 271-277.
Borte S, Liebert UG, Borte M, Sack U. Efficacy of measles, mumps and rubella revaccination in children with juvenile idiopathic arthritis treated with methotrexate and etanercept. Rheumatology, 48 (2009), 2, S. 144-148.
Borte S, Pan-Hammarstrom Q, Liu C, Sack U, Borte M, Wagner U, Graf D, Hammarström L. Interleukin-21 restores immunoglobulin production ex vivo in patients with common variable immunodeficiency and selective IgA deficiency. Blood, 114 (2009), 19, S. 4089-4098.
Burkhardt J, Petit-Teixeira E, Teixeira VH, Kirsten H, Garnier S, Ruehle S, Oeser C, Wolfram G, Scholz M, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Pascual-Salcedo D, Bombardieri S, Dequeker J, Radstake TR, Van Riel P, van de Putte L, Bardin T, Prum B, Buchegger-Podbielski U, Emmrich F, Melchers I, Cornelis F, Ahnert P. Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis. J Rheumatol, 36 (2009), 10, S.2149-2157.
Conant G, Stadler PF. Solvent exposure imparts similar selective pressures across a range of yeast proteins. Mol Biol Evol, 26 (2009), 5, S. 1155-1161.
Fisher M, Feuerstein G, Howells DW, Hurn PD, Kent TA, Savitz SI, Lo EH; STAIR Group. Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke, 40 (2009), 6, S. 2244-2250.
Fricke S, Ackermann M, Stolzing A, Schimmelpfennig C, Hilger N, Jahns J, Hildebrandt G, Emmrich F, Ruschpler P, Pösel C, Kamprad M, Sack U. Allogeneic non-adherent bone marrow cells facilitate hematopoietic recovery but do not lead to allogeneic engraftment. PLoS One (2009), Jul 7, 4(7), e6157.
Fricke S, Fricke C, Schimmelpfennig C, Oelkrug C, Schönfelder U, Blatz R, Faber S, Zilch C, Hilger N, Ruhnke M, Rodloff A. New Real-time PCR assay for the differentiation of Candida species. Appl Microbiol (2009) (accepted JAM-2009-2135).
Härtig W, Reichenbach A, Voigt C, Boltze J, Bulavina L, Schuhmann MU, Seeger J, Schusser GF, Freytag C, Grosche J. Triple fluorescence labelling of neuronal, glial and vascular markers revealing pathological alterations in various animal models. J Chem Neuroanat, 37 (2009), 2, S. 128-138.
Heinrich A, Riethmüller D, Gloger M, Schusser GF, Giese M, Ulbert S. RNA interference protects horse cells in vitro from infection with Equine Arteritis Virus. Antivir Res, 81 (2009), 3, S. 209-216.
Heintz D, Gallien S, Wischgoll S, Ullmann AK, Schaeffer C, Kretzschmar AK, van Dorsselaer A, Boll M. Differential membrane proteome analysis reveals novel proteins involved in the degradation of aromatic compounds in Geobacter metallireducens. Mol Cell Proteomics, 8 (2009), 9, S. 2159-2169.
Hellmuth M, Imrich W, Klöckl W, Stadler PF. Approximate graph products. Eur J Combin, 30 (2009), 5, S. 1119-1133.
Herberth G, Gubelt R, Röder S, Krämer U, Schins RP, Diez U, Borte M, Heinrich J, Wichmann HE, Herbarth O, Lehmann I, LISA plus study group. Increase of inflammatory markers after indoor renovation activities: the LISA birth cohort study. Pediatr Allergy Immu, 20 (2009), 6, S. 563-570.
Hertel J, De Jong D, Marz M, Rose D, Tafer H, Tanzer A, Schierwater B, Stadler PF. Non-coding RNA annotation of the genome of Trichoplax adhaerens. Nucleic Acids Res, 37 (2009), 5, S. 1602-1615.
Hoffmann S, Otto C, Kurtz S, Sharma CM, Khaitovich P, Vogel J, Stadler PF, Hackermüller J. Fast Mapping of Short Sequences with Mismatches, Insertions and Deletions Using Index Structures. PLoS Comput Biol, 5 (2009), 5(9), e1000502.
Jaen O, Petit-Teixeira E, Kirsten H, Ahnert P, Semerano L, Pierlot C, Cornelis F, Boissier MC, Falgarone G; European Consortium on Rheumatoid Arthritis Families. No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis. Arthritis Res Ther. 2009;11(1):R5. Epub 2009 Jan 13.
Kaczkowski B, Torarinsson E, Reiche K, Havgaard JH, Stadler PF, Gorodkin J. Structural profiles of human miRNA families from pairwise clustering. Bioinformatics, 25 (2009), 3, S. 291-294.
Kirsten H, Burkhardt J, Hantmann H, Hunzelmann N, Vaith P, Ahnert P, Melchers I. 5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population. Arthritis Res Ther, 11 (2009), 2, S. 403.
Kirsten H, Petit-Teixeira E, Hantmann H, Reichardt J, Burkhardt J, Emmrich F, Cornelis F, Ahnert P. A family-based study does not support the association of a functional polymorphism in the gene for endothelial nitric oxide synthase with risk for rheumatoid arthritis. Scand J Rheumatol, 38 (2009), 4, S. 320-321.
Kirsten H, Petit-Teixeira E, Scholz M, Hasenclever D, Hantmann H, Heider D, Wagner U, Sack U, Hugo Teixeira V, Prum B, Burkhardt J, Pierlot C, Emmrich F, Cornelis F, Ahnert P. Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study. Arthritis Res Ther, 11 (2009), 3, R60.
Krämer U, Sugiri D, Ranft U, Krutmann J, von Berg A, Berdel D, Behrendt H, Kuhlbusch T, Hochadel M, Wichmann HE, Heinrich J, GINIplus and LISAplus study groups. Eczema, respiratory allergies, and traffic-related air pollution in birth cohorts from small-town areas. J Dermatol Sci, 56 (2009), 2, S. 99-105.
Krupka I, Knauer J, Lorentzen L, O‘Connor TP, Saucier J, Straubinger RK. Borrelia burgdorferi sensu lato species in Europe induce diverse immune responses against C6 peptides in infected mice. Clin Vaccine Immunol, 16 (2009), 11, S. 1546-1562.
Lee SM, Grass G, Kim G M, Dresbach C, Zhang L, Gösele U, Knez M. Low-temperature ZnO atomic layer deposition on biotemplates: flexible photocatalytic ZnO structures from Eggshell Membranes. Phys Chem Chem Phys, 11 (2009), 19, S. 3608-3614.
Meier H, Bullinger J, Marx G, Deten A, Horn LC, Rassler B, Zimmer HG, Briest W. Crucial role of interleukin-6 in the development of norepinephrine-induced left ventricular remodeling in mice. Cell Physiol Biochem, 23 (2009), 3-4, S. 327-334.
Quintana L, zur Nieden NI, Semino CE. Morphogenetic and regulatory mechanisms during developmental chondrogenesis. Tissue Eng Pt B-Rev, 15 (2009), 1, S. 29-41.
Sack U, Conrad K, Csernok E, Frank I, Hiepe F, Krieger T, Kromminga A, Landenberg P, Messer G, Witte T, Mierau R, die deutsche EASI-Gruppe (European Autoimmunity Standardization Initiative). Autoantikörpernachweis mittels indirekter Immunfluoreszenz an HEp-2-Zellen. Deut Med Wochenschr, 134 (2009), 24, S. 1278-1282.
Sack U, Conrad K, Csernok E, Frank I, Hiepe F, Krieger T, Kromminga A, von Landenberg P, Messer G, Witte T, Mierau R, German EASI (European Autoimmunity Standardization Initiative). Autoantibody detection using indirect immunofluorescence on HEp-2 cells. Ann NY Acad Sci, 1173 (2009), S. 166-73.
Saver JL, Albers GW, Dunn B, Johnston KC, Fisher M, STAIR VI Consortium. Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials. Stroke, 40 (2009), 7, S. 2594-2600.
Scheibye-Alsing K, Hoffmann S, Frankel A, Jensen P, Stadler PF, Mang Y, Tommerup N, Gilchrist MJ, Nygard AB, Cirera S, Jorgensen CB, Fredholm M, Gorodkin J. Sequence assembly: review. Comput Biol Chem, 33 (2009), 2, S. 121-136.
Schlomann U, Schwamborn JC, Müller M, Fässler R, Püschel AW. The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase. J Cell Sci. 2009 Jun 15;122(Pt 12):2034-42. Epub 2009 May 19.
Scholz M, Ackermann M, Emmrich F, Loeffler M, Kamprad M. Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastin schedules in a chemotherapy mouse model. Biologics 3 (2009), S. 27-37.
Scholz M, Kamprad M, Ackermann M, Löffler M, Emmrich F, Engel Ch. A Pharmacokinetic Model of Filgrastim and Pegfilgrastim application in Normal and Cyclophosphamide Induced Granulopenic Mice. Cell Proliferat 42 (2009), 6, S. 813-22.
Simon P, Burkhardt U, Sack U, Kaisers UX, Muensterer OJ. Inflammatory Response Is No Different in Children Randomized to Laparoscopic or Open Appendectomy. J Laparoendosc Adv A, 19 (2009), Suppl 1, S. S71-S76.
Sommer G, Kralisch S, Stangl V, Vietzke A, Köhler U, Stepan H, Faber R, Schubert A, Lössner U, Bluher M, Stumvoll M, Fasshauer M. Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells. J Cell Biochem, 106 (2009), 4, S. 729-37.
Stadler PF, Chen JJ, Hackermüller J, Hoffmann S, Horn F, Khaitovich P, Kretzschmar AK, Mosig A, Prohaska SJ, Qi X, Schutt K, Ullmann K. Evolution of vault RNAs. Mol Biol Evol, 26 (2009), 9, S. 1975-91.
Stroh A, Boltze J, Sieland K, Hild K, Gutzeit C, Jung T, Kressel J, Hau S, Reich D, Grune T, Zimmer C. Impact of magnetic labeling on human and mouse stem cells and their long-term magnetic resonance tracking in a rat model of Parkinson disease. Mol Imaging, 8 (2009), 3, S. 166-78.
Tessema B, Muche A, Bekele A, Reissig D, Emmrich F, Sack U. Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia. A five - year retrospective study. BMC Public Health, 4 (2009), 371.
Wechsler L, Steindler D, Borlongan C, Chopp M, Savitz S, Deans R, Caplan L, Hess D, Mays RW, Boltze J, Boncoraglio G, Borlongan CV, Caplan LR, Carmichael ST, Chopp M, Davidoff AW, Deans RJ, Fisher M, Hess DC, Kondziolka D, Mays RW, Norrving B, Parati E, Parent J, Reynolds BA, Gonzalez-Rothi LJ, Savitz S, Sanberg P, Schneider D, Sinden JD, Snyder E, Steinberg GK, Steindler D, Wechsler L, Weiss MD, Weiss S, Victor S, Zheng T. Stem Cell Therapies as an Emerging Paradigm in Stroke Participants. Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke. Stroke, 40 (2009), 2, S. 510-5.
Wilcke A, Weissfuss J, Kirsten H, Wolfram G, Boltze J,Ahnert P. The role of gene DCDC2 in German dyslexics. Ann Dyslexia, 59 (2009), 1, S. 1-11.
Yerebakan C, Klopsch C, Prietz S, Boltze J, Vollmar B, Liebold A, Steinhoff G, Sandica E. Pressure-volume loops: feasible for the evaluation of right ventricular function in an experimental model of acute pulmonary regurgitation? Interact Cardiovasc Thorac Surg, 9 (2009), 2, S. 163-8.
Yerebakan C, Sandica E, Prietz S, Klopsch C, Ugurlucan M, Kaminski A, Abdija S, Lorenzen B, Boltze J, Nitzsche B, Egger D, Barten M, Furlani D, Ma N, Vollmar B, Liebold A, Steinhoff G. Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload. Cell Transplant, 18 (2009), 8, S. 855-68.

Publikationen 2008

Amemiya CT, Prohaska SJ, Hill-Force A, Cook A, Wasserscheid J, Ferrier DEK, Pascual-Anaya J, Garcia-Fernandez J, Dewar K, Stadler PF. The amphioxus Hox cluster: Characterization, comparative genomics, and evolution. J Exp Zool Part B 310B (2008), 5, S. 465-477.
Aupperle H, März I, Schubert A, Dinges G, Thielebein J, Schoon HA. Störungen des Metabolismus der extrazellularmatrix des Herzens bei der kaninen idiopathischen dilatativen Kardiomyopathie. Der praktische Tierarzt 89 (2008), 12, S. 998-1005.
Bernhart SH, Hofacker IL, Will S, Gruber AR, Stadler PF. RNAalifold. Improved consensus structure prediction for RNA alignments. BMC Bioinformatics. Online journal 9 (2008), Art. 474, 13S.
Bockamp E, Sprengel R, Eshkind L, Lehmann T, Braun JM, Emmrich F, Hengstler JG. Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration. Regen Med 3 (2008), 2, S. 217-35.
Bold A, Wurth R, Keller T, Trahorsch T, Voigt P, Schubert S, Sack U. Low-cost enumeration of CD4+ T cells using a density-based negative selection method (RosettaSepTM) for the monitoring of HIV-infected individuals in non-OECD countries. Cytom Part A 73 (2008), 1, S. 28-35.
Boltze J, Förschler A, Nitzsche B, Waldmin D, Hoffmann A, Boltze CM, Oreyer AY, Goldammer A, Reischauer A, Härtig W, Geiger KD, Barthel H, Emmrich F, Gille U. Permanent middle cerebral artery occlusion in sheep: a novel large animal model of focal cerebral ischemia. J Cerebr Blood F Met 28 (2008), 12, 1951-64.
Cepok S, Hoffmann S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wasmuth R, Hemmer B. HLA-DRB1 0401 and HLA-DRB1 0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis. J Neuroimmunol 203 (2008), 2, S. 194.
Daegelmann C, Herberth G, Röder S, Herbarth O, Giese T, Krämer U, Behrendt H, Borte M, Heinrich J, Emmrich F, Lehmann I; LISAplus study group. Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children. Clin Exp Allergy 38 (2008), 3, S. 438-48.
Davis LA, zur Nieden NI. Mesodermal fate decisions of a stem cell: the Wnt switch. Cell Mol Life Sci 65 (2008), 17, S. 2658-2674.
Dress AWM, Flamm C, Fritzsch G, Grünewald S, Kruspe M, Prohaska SJ, Stadler PF. Noisy: Identification of problematic columns in multiple sequence alignments. Algorithm Mol Biol. Online journal 3 (2008), Art. 7, 10S.
Focke A, Schwarz S, Foerschler A, Scheibe J, Milosevic J, Zimmer C, Schwarz J. Labeling of human neural precursor cells using ferromagnetic nanoparticles. Magn Reson Med. 2008 Dec;60(6):1321-8.
Geis M, Flamm C, Wolfinger MT, Tanzer A, Hofacker IL, Middendorf M, Mandl C, Stadler PF, Thurner C. Folding kinetics of large RNAs. J Mol Biol 379 (2008), 1, S. 160-173.
Gessner C, Dihazi H, Brettschneider S, Hammerschmidt S, Kuhn H, Eschrich K, Keller T, Engelmann L, Sack U, Wirtz H. Presence of cytokeratins in exhaled breath condensate of mechanical ventilated patients. Resp Med 102 (2008), 2, S. 299-306.
Goettsch W, Schubert A, Morawietz H. Expression of human endothelinconverting enzyme isoforms: role of angiotensin II. Can J Physiol Pharm 86 (2008), 6, S. 299-309.
Gruber AR, Kilgus C, Mosig A, Hofacker IL, Hennig W, Stadler PF. Arthropod 7SK RNA. Mol Biol Evol 25 (2008), 9, S. 1923-1930.
Hau S, Reich DM, Scholz M, Naumann W, Emmrich F, Kamprad M, Boltze, J. Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro. BMC Neurosci (2008), 9, S. 30.
Haussig S, Schubert A, Mohr FW, Dhein S. Sub-chronic nicotine exposure induces intercellular communication failure and differential down-regulation of connexins in cultured human endothelial cells. Atherosclerosis 196 (2008), 1, S. 210-8.
Hemdan NY. The role of interleukin-12 in the heavy metal-elicited immunomodulation: relevance of various evaluation methods. J Occup Med Toxicol 3 (2008), Art 25, 14S.
Hertel J, Hofacker IL, Stadler PF. SnoReport: Computational identification of snoRNAs with unknown targets. Bioinformatics 24 (2008), 2, S. 158-164.
Hoffmann S, Cepok S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wassmuth R, Hemmer B. HLA-DRB1*0401 and HLADRB1* 0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis. Am J Hum Genet 83 (2008), 2, S. 219-27.
Hollenbach M, Hintersdorf A, Huse K, Sack U, Bigl M, Groth M, Santel T, Buchold M, Lindner I, Otto A, Sicker D, Schellenberger D, Almendinger J, Pustowoit B, Birkemeyer C, Platzer M, Oerlecke I, Hemdan NY, Birkenmeier G. Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors. Biochem Pharmacol 76 (2008), 5, S. 631-644.
Hoppe A, Kamprad M, Wegmann C, Wötzel M, Hauss J, Emmrich F, Fangmann J, Sack U. Natürliche Killerzellen und natürliche Killer-T-Zellen bei Nierentransplantation. Laboratoriumsmedizin 32 (2008), 3, S. 140-147.
Jochl C, Rederstorff M, Hertel J, Stadler PF, Hofacker IL, Schrettl M, Haas H, Hüttenhofer A. Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis. Nucleic Acids Res 36 (2008), 8, S. 2677-2689.
Jung C, Stöckle C, Wiesmüller KH, Laub R, Emmrich F, Jung G, Melms A. Complementary strategies to elucidate T helper cell epitopes in myasthenia gravis. J Neuroimmunol 201/202 (2008), S. 41-49.
Kendziorra K, Barthel H, Erbs S, Emmrich F, Hambrecht R, Schuler G, Sabri O, Kluge R. Effect of Progenitor Cells on Myocardial Perfusion and Metabolism in Patients After Recanalization of a Chronically Occluded Coronary Artery. J Nucl Med 48 (2008), 4, S. 557-563.
Kirsten H, Blume M, Emmrich F, Hunzelmann N, Mierau R, Rzepka R, Vaith P, Witte T, Melchers I, Ahnert P. No association between Systemic Sclerosis and the C77G Polymorphism in the Human PTPRC (CD45) Gene. J Rheumatol 35 (2008), 9, S. 1817-1819.
Klemm K, Flamm C, Stadler PF. Funnels in energy landscapes. Eur Phys J B 63 (2008), 3, S. 387-391.
Kralisch S, Sommer G, Stangl V, Köhler U, Kratzsch J, Stepan H, Faber R, Schubert A, Lössner U, Vietzke A, Bluher M, Stumvoll M, Fasshauer M. Secretory products from human adipocytes impair endothelial function via nuclear factor kappaB. Atherosclerosis 196 (2008), 2, S. 523-31.
Krauss V, Thummler C, Georgi F, Lehmann J, Stadler PF, Eisenhardt C. Near intron positions are reliable phylogenetic markers: An application to holometabolous insects. Mol Biol Evol 25 (2008), 5, S. 821-830.
Krupp W, Holland H, Koschny R, Bauer M, Schober R, Kirsten H, Livrea M, Meixensberger J, Ahnert P. Genome-wide genetic characterization of an atypical meningioma by single-nucleotide polymorphism array-based mapping and classical cytogenetics. Cancer Genet Cytogenet. 2008 Jul 15;184(2):87-93.
Kyaw WO, Uhlig A, Koller G, Sack U, Schusser GF. Freies Hämoglobin und Tumor-Nekrose-Faktor-Alpha im Blut von Pferden mit Kolik oder akuter Kolitis. Berl Munch Tierarztl W 121 (2008), 11-12, S. 440-445.
Lehmann J, Stadler PF, Prohaska SJ. SynBlast: Assisting the analysis of conserved synteny information. BMC Bioinformatics. Online journal 9 (2008), Art. 351, 14S.
Marz M, Kirsten T, Stadler PF. Evolution of spliceosomal snRNA genes in metazoan animals. J Mol Evol 67 (2008), 6, S. 594-607.
Morgenstern V, Zutavern A, Cyrys J, Brockow I, Koletzko S, Krämer U, Behrendt H, Herbarth O, von Berg A, Bauer CP, Wichmann HE, Heinrich J; GINI Study Group; LISA Study Group. Atopic diseases, allergic sensitization, and exposure to trafficrelated air pollution in children. Am J Resp Crit Care M 177 (2008), 12, S. 1331-1337.
Perseke M, Fritzsch G, Ramsch K, Bernt M, Merkle D, Middendorf M, Bernhard D, Stadler PF, Schlegel M. Evolution of mitochondrial gene orders in echinoderms. Mol Phylogenet Evol 47 (2008), 2, S. 855-864.
Pfefferkorn P, Scholz U, Veneruso V, Nikolaus T, Madin K, Eichenlaub U, Schubert A, Lehmann J. Influence of Serum Deprivation on Adherence and Proliferation of Murine Mesenchymal Progenitor Cells Analysed with Roche´s xCELLigence System. Biochemica (2008), 4, S. 14-16.
Pierzchalski A, Robitzki A, Mittag A, Emmrich F, Sack U, O‘Connor JE, Bocsi J, Tarnok A. Cytomics and nanobioengineering. Cytom Part B-Clin Cy 74 (2008), 6, S. 416-426.
Reich DM, Hau S, Stahl T, Scholz M, Naumann W, Emmrich F, Boltze J, Kamprad M. Neuronal hypoxia in vitro: investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells. BMC Neurosci (2008), 9, S. 91.
Rose D, Hertel J, Reiche K, Stadler PF, Hackermüller J. NcDNAlign: plausible multiple alignments of non-proteincoding genomic sequences. Genomics 92 (2008), 1, S. 65-74.
Rose D, Jöris J, Hackermüller J, Reiche K, Li Q, Stadler PF. Duplicated RNA genes in teleost fish genomes. J Bioinform Comput Biol 6 (2008), 6, 1157-75.
Sack U, Emmrich F. Monoklonale Antikörper: Prinzipien, Herstellung, Anwendung und Nebenwirkungen. Internist 49 (2008), 8, S. 921-928.
Santel T, Pflug G, Hemdan NY, Schafer A, Hollenbach M, Buchold M, Hintersdorf A, Lindner I, Otto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebhardt R, Platzer M, Weiss T, Vijayalakshmi MA, Kruger M, Birkenmeier G. Curcumin inhibits glyoxalase 1: a possible link to its antiinflammatory and anti-tumor activity. PLoS ONE (2008), 3, S. e3508.
Schimmelpfennig C. Biolumineszenz- und Fluoreszenz-Imaging: Ein neues Verfahren zur nicht-invasiven Bildgebung von zellbiologischen Prozessen in Kleintieren. Ingenieur Nachrichten (2008), 2, S. 10.
Schimmelpfennig C, Schmiedeknecht A, Emmrich F. Visualisierung von Immunfunktionen mithilfe von Biolumineszenz Imaging. Biospektrum 14 (2008), 5, S. 481-482.
Schoefer Y, Zutavern A, Brockow I, Schäfer T, Krämer U, Schaaf B, Herbarth O, von Berg A, Wichmann HE, Heinrich J; LISA study group. Health risks of early swimming pool attendance. Int J Hyg Envir Heal 211 (2008), 3-4, S. 367-73.
Schulz SM, Köhler G, Schütze N, Knauer J, Straubinger RK, Chackerian AA, Witte E, Wolk K, Sabat R, Iwakura Y, Hölscher C, Müller U, Kastelein RA, Alber G. Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is asso ciated with IL-23-dependent IL-22, but not IL-17. J Immunol 181 (2008), 11, S. 7891-901.
Sonnleitner E, Sorger-Domenigg T, Madej MJ, Findeiss S, Hackermüller J, Hüttenhofer A, Stadler PF, Bläsi U, Moll I. Detection of small RNAs in Pseudomonas aeruginosa by RNomics and structure-based bioinformatic tools. Microbiology 154 (2008), 10, S. 3175-87.
Stolzing A, Jones E, McGonagle D, Scutt A. Age related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies. Mech Ageing Dev, 129 (2008), 3, S. 163-173.
Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, Lehmann J, Sack U. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytom Part A 73 (2008), 3, S. 351-360.
Trepnau D, Ulrich E, Uhlig R, Lindner T, Selbitz HJ, Rösler U, Gabert J, Bergfeld U, Fehlhaber K, Brabetz W, Lehmann J. Antikörperantwort nach Impfung von Mastschweinen mit einem Salmonella-Typhimurium-Lebendimpfstoff in Abhängigkeit von der Applikationsform. Berl Munch Tierarztl 121 (2008), 9-10, S. 334-340.
Ueberham E, Lindner R, Kamprad M, Hiemann R, Hilger N, Woithe B, Mahn D, Cross M, Sack U, Gebhardt R, Arendt T, Ueberham U. Oval cell proliferation in p16INK4a expressing mouse liver is triggered by chronic growth stimuli. J Cell Mol Med 12 (2008), 2, S. 622-638.
Weimann A, Eisele RM, Pawellek S, Hippler-Benscheid M, Rüggeberg A, Cammann H, Radke C, Müller C, Klupp J, Sack U, Lun A. Diagnostic value of peripheral blood markers for acute rejection in LTX-patients receiving anti IL-2R antibodies. Laboratoriumsmedizin 32 (2008), 3, S. 148-157.
Willms H, Wiechmann V, Sack U, Gillissen A. Tracheobronchopathia osteochondroplastica: A rare cause of chronic cough with haemoptysis. Cough 4 (2008), 4, 4S.
Zutavern A, Brockow I, Schaaf B, von Berg A, Diez U, Borte M, Kraemer U, Herbarth O, Behrendt H, Wichmann HE, Heinrich J; LISA Study Group. Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA. Pediatrics (2008), 121, S. e44-52.

Publikationen 2007

Ahnert P, Kirsten H. Association of ITGAV supports a role of angiogenesis in rheumatoid arthritis. Arthritis Res Ther. 2007;9(5):108.
Athanasius F, Bompfünewerer Consortium, Backofen R, Bernhart SH, Flamm C, Fried C, Fritzsch G, Hackermüller J, Hertel J, Hofacker IL, Missal K, Mosig A, Prohaska SJ, Rose D, Stadler PF, Tanzer A, Washietl S, Will S. RNAs everywhere: genome-wide annotation of structured RNAs. J Exp Zool Part B (2007), 308, S. 1-25.
Aupperle H, Garbade J, Schubert A, Barten M, Dhein S, Schoon HA, Mohr FW. Effects of autologous stem cells on immunohistochemical patterns and gene expression of metalloproteinases and their tissue inhibitors in doxorubicin cardiomyopathy in a rabbit model. Vet Pathol 44 (2007), 4, S. 494-503.
Averbeck M, Gebhardt C, Emmrich F, Treudler R, Simon JC. Immunologic principles of allergic disease. J Dtsch Dermatol Ges 5 (2007), 11, S. 1015-28.
Backofen R, Flamm C, Fried C, Fritzsch G, Hackermüller J, Hertel J, Hofacker IL, Missal K, Prohaska SJ, Mosig A, Rose D, Stadler PF, Tanzer A, Washietl S, Will S. RNAs everywhere: genome-wide annotation of structured RNAs. J Exp Zool Part B, 308B (2007), 1, S. 1-25.
Bernt M, Merkle D, Ramsch K, Fritzsch G, Perseke M, Bernhard D, Schlegel M, Stadler PF, Middendorf M. CREx: inferring genomic rearrangements based on common intervals. Bioinformatics 23 (2007), 21, S. 2957-2958.
Brulport M, Schormann W, Bauer A, Hermes M, Elsner C, Hammersen FJ, Beerheide W, Spitkovsky D, Hartig W, Nussler A, Horn LC, Edelmann J, Pelz-Ackermann O, Petersen J, Kamprad M, von Mach M, Lupp A, Zulewski H, Hengstler JG. Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers. Hepatology 46 (2007), 3, S. 861-870.
Brumme S, Arnold T, Sigmarsson H, Lehmann J, Scholz HC, Hardt WD, Hensel A, Truyen H, Roesler U. Impact of Salmonella Typhimurium DT104 Virulence Factors invC and sseD affecting the onset, clinical course, colonization patterns and immune response of porcine salmonellosis. Vet Microbiol, 124 (2007), 3-4, S. 274-285.
Emmrich, F. Regenerative Medicine Today. BioWorld EUROPE Special Edition 1 (2007), S. 2-4.
ENCODE Project Consortium. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007), 447, S. 799-816.
Fangmann J, Wegmann C, Hoppe A, Martin P, Sack U, Harms J, Faber S, Emmrich F. Characterization of dendritic cell subsets in patients undergoing renal transplantation. Transplant Proc 39 (2007), 10, S. 3101-3104.
Förschler A, Boltze J, Waldmin D, Gille U, Zimmer C. MRI of experimental focal cerebral ischemia in sheep. Rofo 179 (2007), 5, S. 516-24.
Gebauer CM, Lenk H, Friedrich W, Sack U, Schuster V. Severe clinical course of Wiskott-Aldrich-syndrome – clinical course, hematologic, immunologic and genetic findings. Kinder- und Jugendmedizin (2007), 7, S. 39-44.
Gessner C, Hammerschmidt S, Kuhn H, Hoheisel G, Gillissen A, Sack U, Wirtz H. Breath Condensate nitrite correlates with hyperinflation in chronic obstructive pulmonary disease. Resp Med 101 (2007), 11, S. 2271-2278.
Hackermüller J, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447 (2007), 7146, S. 799-816.
Hemdan NY, Emmrich F, Faber S, Lehmann J, Sack U. Alterations of Th1/Th2 reac tivity by heavy metals – Possible consequences include induction of autoimmune diseases. Ann NY Acad Sci (2007), 1109, S. 129-137.
Hemdan NY, Lehmann I, Wichmann G, Lehmann J, Emmrich F, Sack U. Immunomodulation by mercuric chloride in vitro: application of different cell activation pathways. Clin Exp Immunol 148 (2007), 2, S. 325-37.
Hiemann R, Hilger N, Michel J, Nitschke J, Bohm A, Anderer U, Weigert M, Sack U. Automatic analysis of immunofluorescence patterns of HEp-2 cells. Ann NY Acad Sci 1109 (2007), 1, S. 358-371.
Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Kirsten H, Ahnert P. Comprehensive cytogenetic characterization of an esthesioneuroblastoma. Cancer Genet Cytogenet. 2007 Mar;173(2):89-96.
Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Schober R, Kirsten H, Ganten TM, Ahnert P. Cytogenetic and molecular biological characterization of an adult medulloblastoma. Cancer Genet Cytogen 178 (2007), 2, S. 104-113.
Kaltenhäuser S, Pierer M, Arnold S, Kamprad M, Baerwald C, Hantzschel H, Wagner U. Anti-bodies against cyclic citrullinated peptide are associated with the DRB1 shared epitope and predict joint erosion in rheumatoid arthritis. Rheumatology 46 (2007), 1, S. 100-104.
Kamprad M, Kindler S, Schuetze N, Emmrich F. Flow cytometric immunophenotyping of umbilical cord and peripheral blood haematopoietic progenitor cells by different CD34 epitopes, CD133, P-glycoprotein expression and rhodamine-123 efflux. Transfus Med Hemoth 34 (2007), 3, S. 195-203.
Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, Stadler PF, Hertel J, Hackermüller J, Hofacker IL, Bell I, Cheung E, Drenkow J, Dumais E, Patel S, Helt G, Ganesh M, Ghosh S, Piccolboni A, Sementchenko V, Tammana H, Gingeras TR. RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science 316 (2007), 5830, S. 1484-1488.
Kirsten H, Teupser D, Weissfuss J, Wolfram G, Emmrich F, Ahnert P. Robustness of single-base extension against mismatches at the site of primer attachment in a clinical assay. J Mol Med 85 (2007), 4, S. 361-9.
Kruspe M, Stadler PF. Progressive multiple sequence alignments from triplets. BMC Bioinformatics. Online journal 8 (2007), S. 254.
Löffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermüller J, Kretzschmar AK, Burger R, Gramatzki M, Blumert C, Bauer K, Cvijic H, Ullmann AK, Stadler PF, Horn F. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110 (2007), 4, S. 1330-3.
Meng GL, zur Nieden NI, Liu SY, Cormier JT, Kallos MS, Rancourt DE. Properties of murine embryonic stem cells maintained on human foreskin fibroblasts without LIF. Mol Reprod Dev, 75 (2007), 4, S. 614-622.
Mosig A, Guofeng M, Stadler BMR, Stadler PF. Evolution of the vertebrate Y RNA cluster. Theor Biosci 126 (2007), 1, S. 9-14.
Rose D, Hackermüller J, Washietl S, Reiche K, Hertel J, Findeiß S, Stadler PF, Prohaska SJ. Computational RNomics of drosophilids. BMC Genomics. Online journal 8 (2007), Art. 406.
Saalbach A, Klein C, Sleeman J, Sack U, Kauer F, Gebhardt C, Averbeck M, Anderegg U, Simon JC. Dermal fibroblasts induce maturation of dendritic cells. J Immunol 178 (2007), 8, S. 4966-4974.
Sack U, Bocsi J, Tarnok A. Importance of cytometry for clinical diagnostics and therapy. Transfus Med Hemoth 34 (2007), 3, S. 153-154.
Sack U, Conrad K, Csernok E, Frank I, Haass M, Krieger T, Seyfarth M, Schlosser U, Schmidt R, Witte T. Standardization of autoimmune diagnostics in Germany: activities of the German group in the European Autoimmune Standardization Initiative. Ann NY Acad Sci (2007), 1109, S. 31-36.
Sack U, Gerling F, Tarnok A. Age-related lymphocyte subset changes in the peripheral blood of healthy children – A metastudy. Transfus Med Hemoth 34 (2007), 3, S. 176-181.
Savkovic V, Gantzer H, Reiser U, Selig L, Gaiser S, Sack U, Kloppel G, Mossner J, Keim V, Horn F, Bodeker H. Clusterin is protective in pancreatitis through anti-apoptotic and anti-inflammatory properties. Biochem Bioph Res Co 356 (2007), 2, S. 431-437.
Schloendorn J, Sethe S, Stolzing A. Cellular therapy using microglial cells. Rejuv Res 10 (2007), 1, S. 87-99.
Schmidt A, Haas SJ, Hildebrandt S, Scheibe J, Eckhoff B, Racek T, Kempermann G, Wree A, Pützer BM. Selective targeting of adenoviral vectors to neural precursor cells in the hippocampus of adult mice: new prospects for in situ gene therapy. Stem Cells. 2007 Nov;25(11):2910-8. Epub 2007 Jul 19.
Schwenk M, Sack U, Esser C, Klein R. Diagnostic relevance of the determination of lymphocyte subpopulations in environmental medicine. Int J Hyg Envir Heal 210 (2007), 2, S. 177-198.
Schwamborn JC, Müller M, Becker AH, Püschel AW. Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. EMBO J. 2007 Mar 7;26(5):1410-22. Epub 2007 Feb 22.
Sharma N, Kaur J, Xhu H, zur Nieden NI, Rancourt DE. Characterization of secretory leukocyte protease inhibitor (SLPI) as an inhibitor of implantation serine proteinase. Mol Reprod Dev, 75 (2007), 7, S. 1136-1142.
Stolzing A, Hescheler J, Sethe S. Fusion and regenerative therapies: is immortality really recessive? Rejuv Res 10 (2007), 4, S. 571-86.
Tanneberger K, Kirchberger J, Bar J, Schellenberger W, Rothemund S, Kamprad M, Otto H, Schoneberg T, Edelmann A. A novel form of 6-phosphofructokinase – Identification and functional relevance of a third type of subunit in pichia pastoris. J Biol Chem 282 (2007), 32, S. 23687-23697.
Washietl S, Pedersen JS, Korbel JO, Stocsits C, Gruber AR, Hackermüller J, Hertel J, Lindemeyer M, Reiche K, Tanzer A, Ucla C, Wyss C, Antonarakis SE, Denoeud F, Lagarde J, Drenkow J, Kapranov P, Gingeras TR, Guigó R, Snyder M, Gerstein MB, Reymond A, Hofacker IL, Stadler PF. Structured RNAs in the ENCODE selected regions of the human genome. Genome Res 17 (2007), 6, S. 852-64.
zur Nieden NI, Cormier JT, Rancourt DE, Kallos MS. Embryonic stem cells remain highly pluripotent following long term expansion as aggregates in suspension bioreactors. J Biotechnol 129 (2007), 3, S. 421-432.
zur Nieden NI, Price FD, Davis LA, Everitt R, Rancourt DE. Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for beta-catenin in osteogenic differentiation. Mol Endocrinol 21 (2007), 3, S. 674-685.

Publikationen 2005

Aust G, Kamprad M, Lamesch P, Schmücking E. CXCR6 within T-helper (Th) and T-cytotoxic (Tc) type 1 lymphocytes in Graves’ disease (GD). Eur J Endocrinol, 152 (2005), 4, S. 635-643.
Boltze J, Kowalski I, Geiger K, Reich D, Gunther A, Buhrle C, Egger D, Kamprad M, Emmrich F. Experimental treatment of stroke in spontaneously hypertensive rats by CD34+ and CD34-cord blood cells. Ger Med Sci, 3, Doc09 (2005), 20051110.
Burkhardt C, Müller M, Badde A, Garner CC, Gundelfinger ED, Püschel AW. Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif. FEBS Lett. 2005 Jul 4;579(17):3821-8.
Erbs S, Linke A, Adams V, Lenk K, Thiele H, Diederich KW, Emmrich F, Kluge R, Kendziorra K, Sabri O, Schuler G, Hambrecht R. Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study. Circ Res, 97 (2005), 8, S. 756-762.
Garbade J, Schubert A, Rastan AJ, Lenz D, Walther T, Gummert JF, Dhein S, Mohr FW. Fusion of bone marrow-derived stem cells with cardiomyocytes in a heterologous in vitro model. Eur J Cardio-Thorac, 28 (2005), 5, S. 685-91.
Gessner C, Scheibe R, Wötzel M, Hammerschmidt S, Kuhn H, Engelmann L, Hoheisel G, Sack U. Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease. Resp Med, 99 (2005), 10, S. 1229-1240.
Gielen S, Adams V, Linke A, Erbs S, Mobius-Winkler S, Schubert A, Schuler G, Hambrecht R. Exercise training in chronic heart failure: correlation between reduced local inflammation and improved oxidative capacity in the skeletal muscle. Eur J Cardiov Prev R,12 (2005), 4, S. 393-400.
Hambrecht R, Schulze PC, Gielen S, Linke A, Mobius-Winkler S, Erbs S, Kratzsch J, Schubert A, Adams V, Schuler G. Effects of exercise training on insulin-like growth factor-I expression in the skeletal muscle of non-cachectic patients with chronic heart failure. Eur J Cardiov Prev R,12 (2005), 4, S. 401-6.
Hammerschmidt S, Kuhn H, Sack U, Schlenska A, Gessner C, Gillissen A, Wirtz H. Mechanical stretch alters alveolar type II cell mediator release toward a proinflammatory pattern. Am J Resp Cell Mol, 33 (2005), 2, S. 203-210.
Hemdan NY, Emmrich F, Adham K, Wichmann G, Lehmann I, El-Massry A, Ghoneim H, Lehmann J, Sack U. Dose-dependent modulation of the in vitro cytokine production of human immune competent cells by lead salts. Toxicol Sci, 86 (2005), 1, S. 75-83.
Holtick U, Vockerodt M, Pinkert D, Schoof N, Sturzenhofecker B, Kussebi N, Lauber K, Wesselborg S, Löffler D, Horn F, Trümper L, Kube D. STAT3 is essential for Hodgkin lymphoma cell proliferation and is target of tyrphostin AG17 which confers sensitization for apoptosis. Leukemia, 19 (2005), 6, S. 936-944.
Lange F, Bajtner E, Caspar T, Rintisch C, Nandakumar KS, Sack U, Holmdahl R. Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis. Ann Rheum Dis, 64 (2005), 4, S. 599-605.
Lenk K, Adams V, Lurz P, Erbs S, Linke A, Gielen S, Schmidt A, Scheinert D, Biamino G, Emmrich F, Schuler G, Hambrecht R. Therapeutical potential of blood-derived progenitor cells in patients with peripheral arterial occlusive disease and critical limb ischaemia. Eur Heart J, 26 (2005), 18, S. 1903-1909.
Lenz D, Barten MJ, Hiller S, Tarnok A, Sack U. Regenerative and predictive medicine of cardiovascular disease: the 9th Leipziger Workshop and the 2nd International Workshop on slide based cytometry. Cytom Part A, 64 (2005), 2, S. 110-114.
Linke A, Adams V, Schulze PC, Erbs S, Gielen S, Fiehn E, Mobius-Winkler S, Schubert A, Schuler G, Hambrecht R. Antioxidative effects of exercise training in patients with chronic heart failure. Increase in radical scavenger enzyme activity in skeletal muscle. Circulation, 111 (2005), 14, S. 1763-70.
Mittag A, Lenz D, Gerstner AO, Sack U, Steinbrecher M, Koksch M, Raffael A, Bocsi J, Tarnok A. Polychromatic (eight-color) slide-based cytometry for the phenotyping of leukocyte, NK, and NKT subsets. Cytom Part A, 65 (2005), 2, S. 103-115.
Moche M, Hui DSC, Huse K, Chan KS, Choy DKL, Tannapfel A, Scholz GH, Gosse H, Sack U, Hoheisel G. Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion. Pneumologie, 59 (2005), 8, S. 523-528.
Pelz O, Wu M, Nikolova T, Kamprad M, Ackermann M, Egger D, Emmrich F, Wobus AM, Cross M. Duplex polymerase chain reaction quantification of human cells in a murine background. Stem Cells, 23 (2005), 6, S. 828-833.
Pohlers D, Siegling A, Buchner E, Schmidt-Weber CB, Palombo-Kinne E, Emmrich F, Brauer R, Kinne RW. Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis. Arthritis Res Ther, 7 (2005), 3, S. 445-457.
Rastan AJ, Walther T, Kostelka M, Garbade J, Schubert A, Stein A, Dhein S, Mohr FW. Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells-an in vitro-model. Eur J Cardio-Thorac, 27 (2005), 1, S. 104-10.
Sack U, Hirth A, Funke B, Wiedemeyer K, Lange F, Troltzsch M, Tannapfel A, Gebhardt R, Emmrich F, Lehmann J. A novel model of fibroblast-mediated cartilage destruction. Scand J Immunol, 61 (2005), 1, S. 18-28.
Sack U, Hoffmann M, Zhao XJ, Chan KS, Hui DS, Gosse H, Engelmann L, Schauer J, Emmrich F, Hoheisel G. Vascular endothelial growth factor in pleural effusions of different origin. Eur Respir J, 25 (2005), 4, S. 600-604.
Sack U, Sehm B, Kahlenberg F, Murr A, Lehmann J, Tannapfel A, Uberla K, Moessner A, Dietrich A, Emmrich F, Lange F, Jungel A, Braun JM, Anderegg U. Investigation of arthritic joint destruction by a novel fibroblastbased model. Ann NY Acad Sci 1051 (2005), 1, S. 291-298.
Schastak S, Jean B, Handzel R, Kostenich G, Hermann R, Sack U, Orenstein A, Wang YS, Wiedemann P. Improved pharmacokinetics, biodistribution and necrosis in vivo using a new near infra-red photosensitizer: tetrahydroporphyrin tetratosylat. J Photoch Photobio B, 78 (2005), 3, S. 203-213.
Schneider A, Sack U, Rothe K, Bennek J. Peritoneal taurolidine lavage in children with localised peritonitis due to appendicitis. Pediatr Surg Int 21 (2005), 6, S. 445-448.
Stolzing A, Sethe S, Grune T. Chronically active - role of oxidative stress in age and neuropathology. Redox Rep, 10 (2005), 4, S. 207-13.
Wötzel M, Schröder S, Sack U. Differentiation of anti-platelet antibodies using microspheres and flow cytometry. J Lab Clin Med (2005), 29, S. 368-376.
zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ. Induction of chondro-, osteoand adipogenesis in embryonic stem cells by bone morphogenetic protein-2: Effect of co-factors on differentiating lineages. BMC Dev Biol 5 (2005), 1, S. 1-15.

Publikationen 2006

Baumann JG. Intracellular restriction factors in mammalian cells – an ancient defense system finds a modern foe. Curr HIV Res, 4 (2006), 2, S. 141-168.
Birkenmeier G, Nicklisch S, Pockelt C, Mossie A, Steger V, Glaser C, Hauschildt S, Usbeck E, Huse K, Sack U, Bauer M, Schafer A. Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: modes of action and impact on lethality. J Pharmacol Exp Ther, 318 (2006), 2, S. 762-771.
Bocsi J, Lenz D, Mittag A, Varga VS, Molnar B, Tulassay Z, Sack U, Tarnok A. Automated four-color analysis of leukocytes by scanning fluorescence microscopy using quantum dots. Cytom Part A, 69 (2006), 3, S. 131-134.
Bocsi J, Mittag A, Sack U, Gerstner AO, Barten MJ, Tarnok A. Novel aspects of systems biology and clinical cytomics. Cytom Part A, 69 (2006), 3, S. 105-108.
Boltze J, Kowalski I, Forschler A, Schmidt U, Wagner D, Lobsien D, Emmrich J, Egger D, Kamprad M, Blunk J, Emmrich F. The stairway: a novel behavioral test detecting sensomotoric stroke deficits in rats. Artif Organs, 30 (2006), 10, S. 756-763.
Brocke-Heidrich K, Ge B, Cvijic H, Pfeifer G, Loffler D, Henze C, McKeithan TW, Horn F. BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription. Oncogene, 25 (2006), 55, S. 7297-7304.
Colsman A, Sticherling M, Stopel C, Emmrich F. Computer-assisted learning in medicine : how to create a novel software for immunology. Arch Dermatol Res, 298 (2006), 1, S. 1-6.
Cormier JT, zur Nieden NI, Rancourt DE, Kallos MS. Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors. Tissue Eng, 12 (2006), 11, S. 3233-3245.
Dietrich A, Stockmar C, Aust G, Endesfelder S, Guetz A, Sack U, Schoenfelder M, Hauss J. Intraoperative subcutaneous or intrasplenic vaccination with modified autologous tumor cells leads to enhanced survival in a mouse tumor model. J Cancer Res Clin, 132 (2006), 6, S. 379-388.
Ehlers J, Alt M, Trepnau D, Lehmann J. Anwendung neuer Immunglobulin-isotypspezifischer ELISA-Systeme zur Erkennung von Salmonelleninfektionen bei Schweinen. Berl Munch Tierarztl 119 (2006), 11-12, S. 461-466.
Emmrich F. Regenerative Medizin – Made in Germany. Zeitschrift für Regenerative Medizin, 1. Jahrg. (2006), 1.
Funke B, Jungel A, Schastak S, Wiedemeyer K, Emmrich F, Sack U. Transdermal photodynamic therapy-a treatment option for rheumatic destruction of small joints? Laser Surg Med, 38 (2006), 9, S. 866-874.
Giese M, Liebert UG, Schneider T, Bock K, Zahn N, Uhlig A, Schusser GF. Therapeutical immunization of EAV-infected horses by DNA-Vaccination. Reprod Domest Anim 41 (2006), 4, S. 297-298.
Härtig W, Lehmann J, Stieler J, Singer D, Grosche J, Arendt T, Hoffmann R. Simultaneous detection of tau phospho-epitopes with haptenylated antibodies. Neuroreport, 17 (2006), 9, S. 869-875.
Hemdan NY, Emmrich F, Sack U, Wichmann G, Lehmann J, Adham K, Lehmann I. The in vitro immune modulation by cadmium depends on the way of cell activation. Toxicology 222 (2006), 1-2, S. 37-45.
Hiemann R, Hilger N, Sack U, Weigert M. Objective quality evaluation of fluorescence images to optimize automatic image acquisition. Cytom Part A, 69 (2006), 3, S. 182-184.
Kirsten H, Dienst S, Emmrich F, Ahnert P. CalcDalton: a tool for multiplex genotyping primer design for single-base extension reactions using cleavable primers. Biotechniques, 40 (2006), 2, S. 158-160.
Koschny R, Holland H, Koschny T, Vitzthum HE. Comparative genomic hybridization pattern of non-anaplastic and anaplastic oligodendrogliomas – a meta-analysis. Pathol Res Pract, 202 (2006), 1, S. 23-30.
Lange F, Hartl S, Ungethuem U, Kuban RJ, Hammerschmidt S, Faber S, Morawietz L, Wirtz H, Emmrich F, Krenn V, Sack U. Anti-TNF effects on destructive fibroblasts depend on mechanical stress. Scand J Immunol, 64 (2006), 5, S. 544-553.
Lehmann J, Springer S, Werner CE, Lindner T, Bellmann S, Straubinger RK, Selbitz HJ, Alber G. Immunity induced with a Salmonella enterica serovar enteritidis live vaccine is regulated by Th1-cell-dependent cellular and humoral effector mechanisms in susceptible BALB/c mice. Vaccine, 24 (2006), 22, S. 4779-4793.
Mishto M, Bellavista E, Santoro A, Stolzing A, Ligorio C, Nacmias B, Spazzafumo L, Chiapelli M, Licastro F, Sorbi S, Pession A, Ohm T, Grune T, Franceschi C. Immunoproteasome and LMP2 polymorphism in aged and Alzheimer’s disease brains. Neurobiol Aging, 27 (2006), 1, S. 54-66.
Mittag A, Lenz D, Bocsi J, Sack U, Gerstner AO, Tarnok A. Sequential photobleaching of fluorochromes for polychromatic slide-based cytometry. Cytom Part A, 69 (2006), 3, S. 139-141.
Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Kuss O, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R. Endothelial protection, AT1 blockade and cholesterol-dependent oxidative stress: the EPAS trial. Circulation, 114 (2006), 1, S. 1296-1301.
Mückstein U, Tafer H, Hackermüller J, Bernhart SH, Stadler PF, Hofacker IL. Thermodynamics of RNA-RNA binding. Bioinformatics 22 (2006), 10, S. 1177-1182.
Müller H, Johne R, Schusser G, Giese M, Linke S, Pauli G. West Nile Virus - Causative agent of a zoonosis with increasing significance? Deut Tierarztl Woch 113 (2006), 12, S. 435-439.
Pohl S, Fricke S, Hildebrandt G, Uharek L, Braun JM, Emmrich F. Permanent induction of specific immunotolerance to allograft and prevention of graft-versushost-disease. Zeitschrift für Regenerative Medizin (2006), 1, S. 60.
Poppek D, Keck S, Ermack G, Jung T, Stolzing A, Ullrich O, Davies KJ, Grune T. Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress. Biochem J 400 (2006), 3, S. 511-520.
Rulli SJjr, Muriaux D, Nagashima K, Mirro J, Oshima M, Baumann JG, Rein A. Mutant murine leukemia virus Gag proteins lacking proline at the N-terminus of the capsid domain block infectivity in virions containing wild-type Gag. Virology, 347 (2006), 2, S. 364-371.
Sack U, Biereder B, Elouahidi T, Bauer K, Keller T, Trobs RB. Diagnostic value of blood inflammatory markers for detection of acute appendicitis in children. BMC Surg 6 (2006), 15.
Sack U, Scheibe R, Wötzel M, Hammerschmidt S, Kuhn H, Emmrich F, Hoheisel G, Wirtz H, Gessner C. Multiplex analysis of cytokines in exhaled breath condensate. Cytom Part A, 69 (2006), 3, S. 169-172.
Seleverstov O, Zabirnyk O, Zscharnack M, Bulavina L, Nowicki M, Heinrich JM, Yezhelyev M, Emmrich F, O Regan R, Bader A. Quantum dots for human mesenchymal stem cells labeling. A size-dependent autophagy activation. Nano Lett, 6 (2006), 12, S. 2826-2832.
Selig L, Sack U, Gaiser S, Kloppel G, Savkovic V, Mossner J, Keim V, Bodeker H. Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen. BMC Gastroenterol (2006), 6, S. 30ff.
Sethe S, Scutt A, Stolzing A. Aging of mesenchymal stem cells. Aging Res Rev (2006), 5, S. 91-116.
Singer D, Lehmann J, Hanisch K, Härtig W, Hoffmann R. Neighbored phosphorylation sites as PHF-tau specific markers in Alzheimer’s disease. Biochem Bioph Res Co (2006), 346, S. 819-828.
Stolzing A, Scutt A. Age-related impairment of mesenchymal progenitor cell function. Aging Cell (2006), 5, S. 213-224.
Stolzing A, Scutt A. Effect of reduced culture temperature on antioxidant defences of mesenchymal stem cells. Free Radical Bio Med, 41 (2006), 2, S. 326-38.
Stolzing A, Scutt A. Glucose-induced replicative senescence in mesenchymal stem cells. Rejuv Res, 9 (2006), 1, S. 31-35.
Stolzing A, Sethe S, Scutt A. Stressed stem cells: temperature response in aged mesenchymal stem cells. Stem Cells Dev, 15 (2006), 4, S. 478-87.
Stolzing A, Widmer R, Jung T, Grune T. Tocopherol-mediated modulation of age-related changes in microglial cells: turnover of extracellular oxidized protein material. Free Radical Bio Med 40 (2006), 12, S. 2126-2135.
Stolzing A, Widmer R, Jung T, Voss P, Grune T. Degradation of glycated bovine serum albumin in microglial cells. Free Radical Bio Med, 40 (2006), 6, S. 1017-1027.
Walther T, Schubert A, Wustmann T, Falk V, Walther C, Doll N, Rastan A, Gummert J, Mohr FW. Reverse remodeling of cardiac collagen protein expression after surgical therapy for experimental aortic stenosis. J Heart Valve Dis, 15 (2006), 5, S. 651-6.