Fraunhofer-Institut für Zelltherapie und Immunologie IZI

Publikationsliste

Publikationen 2022

Alaneed R, Naumann M, Pietzsch M, Kressler J. Microbial transglutaminase-mediated formation of erythropoietin-polyester conjugates. J Biotechnol. 2022 Feb 20;346:1-10. doi: 10.1016/j.jbiotec.2022.01.001. Epub 2022 Jan 15.
Allelein S, Aerchlimann K A, Roesch G, Khajehamiri R, Koelsch A, Freese C, Kuhlmeier D. Prostate-specific membrane antigen (PSMA)-positive extracellular vesicles in urine - a potential liquid biopsy strategy for prostate cancer diagnosis? Cancers (Basel). 2022 Jun 17;14(12):2987. doi: 10.3390/cancers14122987
Arbaciauskaite S, Babakhani P, Sandetskaya N, Vitkus D, Jancoriene L, Karosiene D, Karciauskaite D, Zablockiene B, Kuhlmeier D. Self-sampled gargle water direct RT-LAMP as a screening method for the detection of SARS-CoV-2 infections. Diagnostics (Basel). 2022 Mar 22;12(4):775. doi: 10.3390/diagnostics12040775
Arteaga V G, Demand V, Kern K, Strube A, Szardenings M, Muranyi I, Eisner P, Schweiggert-Weisz U. Enzymatic hydrolysis and fermentation of pea protein isolate and its effects on antigenic proteins, functional properties, and sensory profile. Foods. 2022 Jan 4;11(1):118. doi: 10.3390/foods11010118
Arumugam S N, Manohar P, Sukumaran S, Sadagopan S, Loh B, Leptihn S, Nachimuthu R. Antibacterial efficacy of lytic phages against multidrug-resistant Pseudomonas aeruginosa infections in bacteraemia mice models. BMC Microbiol. 2022 Aug 1;22(1):187. doi: 10.1186/s12866-022-02603-0
Bathini P, Sun T, Schenk M, Schilling S, McDannold N J, Lemere C A. Acute effects of focused ultrasound-induced blood-brain barrier opening on anti-pyroglu3 abeta antibody delivery and immune responses. Biomolecules. 2022 Jul 6;12(7):951. doi: 10.3390/biom12070951
Bäumer N, Scheller A, Wittmann L, Faust A, Apel M, Nimmagadda SC, Geyer C, Grunert K, Kellmann N, Peipp M, Kailayangiri S, Ezequiel Gutierrez Suburu ME, Strassert CA, Schenk M, Greune L, Rüter C, Dersch P, Hartmann W, Rossig C, Neri D, Müller-Tidow C, Schwöppe C, Schliemann C, Khandanpour C, Lenz G, Berdel WE, Bäumer S. Electrostatic anti-CD33-antibody-protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia. J Hematol Oncol. 2022 Dec 1;15(1):171. doi: 10.1186/s13045-022-01390-5
Bayly-Jones C, Lupton C J, Fritz C, Venugopal H, Ramsbeck D, Wermann M, Jaeger C, Marco A de, Schiling S, Schlenzig D, Whisstock J C. Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor. Nat Commun. 2022 Oct 19;13(1):6178. doi: 10.1038/s41467-022-33893-7
Beckmann L, Tretbar S, Kitte R, Tretbar M. Anticancer activity of natural and semi-synthetic drimane and coloratane sesquiterpenoids. Molecules. 2022 Apr 13;27(8):2501. doi: 10.3390/molecules27082501
Berneck B S, Rockstroh A, Barzon L, Sinigaglia A, Vocale C, Landini M P, Rabenau H F, Schmidt-Chanasit J, Ulbert S. Serological differentiation of West Nile virus- and Usutu virus-induced antibodies by envelope proteins with modified cross-reactive epitopes. Transbound Emerg Dis. 2022 Sep;69(5):2779-2787. doi: 10.1111/tbed.14429. Epub 2022 Jan 10
Beyer K, Straten V, Remmers S, MacLennan S, MacLennan S, Gandaglia G, Willemse P-P M, Herrera R, Omar M I, Russel B, Huber J, Kreuz M, Asiimwe A, Abbott T, Briganti A, Hemelrijck M van, Roobol M J, Prias Consortium, Erspc Rotterdam Study Group, Pioneer Consortium. Secondary treatment for men with localized prostate cancer: a pooled analysis of PRIAS and ERSPC-Rotterdam data within the PIONEER data platform. J Pers Med. 2022 May 5;12(5):751. doi: 10.3390/jpm12050751
Biadglegne F, Schmidt J R, Engel K M, Lehmann J, Lehmann R T, Reinert A, Koenig B, Schiller J, Kalkhof S, Sack U. Mycobacterium tuberculosis affects protein and lipid content of circulating exosomes in infected patients depending on Tuberculosis disease state. Biomedicines. 2022 Mar 27;10(4):783. doi: 10.3390/biomedicines10040783
Blache U, Ford EM, Ha B, Rijns L, Dankers PYW, Kloxin AM, Snedeker JG, Gentleman E. Engineered hydrogels for mechanobiology. Nature Reviews Methods Primer 2 (2022)
Blache U, Popp G, Duenkel A, Koehl U, Fricke S. Potential solutions for manufacture of CAR T cells in cancer immunotherapy. Nat Commun. 2022 Sep 5;13(1):5225. doi: 10.1038/s41467-022-32866-0
Bluhm A, Schrempel S, Moceri S, Stieler J, Feja M, Schilling S, Schulze A, Hörsten S von, Hartlage-Rübsamen M, Richter F, Roßner S. Alpha synuclein processing by MMP-3 - implications for synucleinopathies. Behav Brain Res. 2022 Sep 26;434:114020. doi: 10.1016/j.bbr.2022.114020. Epub 2022 Jul 21
Bluhm A, Schrempel S, Schilling S, Hoersten, S von, Schulze A, Roßner S, Hartlage-Ruebsamen M. Immunohistochemical demonstration of the pGlu79 α-synuclein fragment in Alzheimer’s disease and its Tg2576 mouse model. Biomolecules. 2022 Jul 20;12(7):1006. doi: 10.3390/biom12071006
Borgolte M, Quint I, Kaiser L, Csuk R, Deigner H-P. A fluorescence-based competitive antibody binding assay for kynurenine, a potential biomarker of kidney transplant failure. Diagnostics (Basel). 2022 Jun 2;12(6):1380. doi: 10.3390/diagnostics12061380
Borgolte M, Riester O, Quint I, Blendinger F, Bucher V, Laufer S, Csuk R, Scotti L, Deigner H-P. Synthesis of a biocompatible benzophenone-substituted chitosan hydrogel as novel coating for PEEK with extraordinary strong antibacterial and anti-biofilm properties. Materials today chemistry 26 (2022), 101176. doi: 10.1016/j.mtchem.2022.101176
Dienelt A, Keller K C, Zur Nieden N. High glucose impairs osteogenic differentiation of embryonic stem cells via early diversion of beta‐catenin from Forkhead box O to T cell factor interaction. Birth Defects Res. 2022 Oct 1;114(16):1056-1074. doi: 10.1002/bdr2.2085. Epub 2022 Sep 26
Donnadieu E , Luu M, Alb M, Anliker B, Arcangeli S, Bonini C, De Angelis B, Choudhary R, Espie D, Galy A, Holland C, Ivics Z, Kantari-Mimoun C, Kersten M J, Koehl U, Kuhn C, Laugel B, Locatelli F, Marchiq I, Markman J, Moresco M A, Morris E, Negre H, Quintarelli C, Rade M, Reiche K, Renner M, Ruggiero E, Sanges C, Stauss H, Themeli M, Van den Brulle J, Hudecek M, Casucci M. Time to evolve: predicting engineered T cell-associated toxicity with next-generation models. J Immunother Cancer. 2022 May;10(5):e003486. doi: 10.1136/jitc-2021-003486
Doß S, Blessing C, Haller K, Richter G, Sauer M. Influence of antibiotics on functionality and viability of liver cells in vitro. Curr Issues Mol Biol. 2022 Oct 3;44(10):4639-4657. doi: 10.3390/cimb44100317
Elbalasy I, Wilharm N, Herchenhahn E, Konieczny R, Mayr S G, Schnauß J. From strain stiffening to softening - rheological characterization of keratins 8 and 18 networks crosslinked via electron irradiation. Polymers (Basel). 2022 Feb 4;14(3):614. doi: 10.3390/polym14030614
Finkensieper J, Issmail L, Fertey J, Rockstroh A, Schopf S, Standfest B, Thoma M, Grunwald T, Ulbert S. Low-energy electron irradiation of tick-borne encephalitis virus provides a protective inactivated vaccine. Front Immunol. 2022 Mar 7;13:825702. doi: 10.3389/fimmu.2022.825702. eCollection 2022
Friedrich M, Aigner A. Therapeutic siRNA: state-of-the-art and future perspectives. BioDrugs. 2022 Sep;36(5):549-571. doi: 10.1007/s40259-022-00549-3. Epub 2022 Aug 23
Friedrich M, Pfeifer G, Binder S, Aigner A, Barbosa P V, Makert G R, Fertey J, Ulbert S, Bodem J, Koenig E-M, Geiger N, Schambach A, Schilling E, Buschmann T, Hauschildt S, Koehl U, Sewald K. Selection and validation of siRNAs preventing uptake and replication of SARS-CoV-2. Front Bioeng Biotechnol. 2022 Mar 2;10:801870. doi: 10.3389/fbioe.2022.801870. eCollection 2022
Fueldner C, Riemschneider S, Haupt J, Jungnickel H, Schulze F, Zoldan K, Esser C, Hauschildt S, Knauer J, Luch A, Kalkhof S, Lehmann J. Aryl hydrocarbon receptor activation by Benzo[a]pyrene prevents development of septic shock and fatal outcome in a mouse model of systemic Salmonella enterica infection. Cells. 2022 Feb 20;11(4):737. doi: 10.3390/cells11040737
Furesi G, Jesus Domingues A M, Alexopoulou D, Dahl A, Hackl M, Schmidt J, Kalkhof S, Kurth T, Taipaleenmaeki H, Conrad S, Hofbauer C, Rauner M, Hofbauer L C. Exosomal miRNAs from prostate cancer impair osteoblast function in mice. Int J Mol Sci. 2022 Jan 24;23(3):1285. doi: 10.3390/ijms23031285
Glienke W, Dragon A C, Zimmermann K, Martyniszyn-Eiben A, Mertens M, Abken H, Rossig C, Altvater B, Aleksandrova K, Arseniev L, Kloth C, Stamopoulou A, Moritz T, Lode H N, Siebert N, Blasczyk R, Goudeva L, Schambach A, Koehl U, Eiz-Vesper B, Esser R. GMP-compliant manufacturing of TRUCKs: CAR T cells targeting GD2 and releasing inducible IL-18. Front Immunol. 2022 Mar 24;13:839783. doi: 10.3389/fimmu.2022.839783. eCollection 2022
Gnoth K, Geissler S, Feldhaus J, Taudte N, Ilse V, Zürner S, Greiser S, Braumann U-D, Rahfeld J-U, Cynis H, Schilling S. Evidence for enhanced efficacy of passive immunotherapy against beta-amyloid in CD33-negative 5xFAD mice. Biomolecules. 2022 Mar 4;12(3):399. doi: 10.3390/biom12030399
Gringmuth M, Walther J, Greiser S, Toussaint M, Schwalm B, Kool M, Kortmann R-D, Glasow A, Patties I. Enhanced survival of high-risk medulloblastoma-bearing mice after multimodal treatment with radiotherapy, decitabine, and abacavir. Int J Mol Sci. 2022 Mar 30;23(7):3815. doi: 10.3390/ijms23073815
Groß R, Lívia Mesquita D L, Issmail L, Uhlig N, Eberlein V, Conzelmann C, Olari L-R, Rauch L, Lawrenz J, Weil T, Mueller J A, Cardoso M B, Gilg A, Larrson O, Hoeglund U, Axberg Pålsson, Tvilum A S, Løvschall K B, Kristensen M M, Spetz A-L, Hontonnou F, Galloux M, Zelikin A N, Grunwald T, Muench J. Macromolecular viral entry inhibitors as broad‐spectrum first‐line antivirals with activity against SARS‐CoV‐2. Adv Sci (Weinh). 2022 Jul;9(20):e2201378. doi: 10.1002/advs.202201378. Epub 2022 May 11
Guedan S, Luu M, Ammar D, Barbao P, Bonini C, Bousso P, Buchholz C J, Casucci M, De Angelis B, Donnadieu E, Espie D, Greco B, Groen R, Huppa J B, Kantari-Mimoun C, Laugel B, Mantock M, Markman J, Morris E, Quintarelli C, Rade M, Reiche K, Rodriguez-Garcia A, Rodriguez-Madoz J R, Ruggiero E, Themeli M, Hudecek M, Marchig I. Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside? J Immunother Cancer. 2022 May;10(5):e003487. doi: 10.1136/jitc-2021-003487
Haehnel S, Rade M, Kaiser N, Reiche K, Horn A, Loeffler D, Blumert C, Rapp F, Horn F, Meixensberger J, Renner C, Mueller W, Gaunitz F, Bechmann I, Winter K. RNA sequencing of glioblastoma tissue slice cultures reveals the effects of treatment at the transcriptional level. FEBS Open Bio. 2022 Feb;12(2):480-493. doi: 10.1002/2211-5463.13353. Epub 2021 Dec 29
Haendler T, Tutmarc C, Freitag J S, Smith D M, Schnauß J. Constraint release for reptating filaments in semiflexible networks depends on background fluctuations. Polymers (Basel). 2022 Feb 12;14(4):707. doi: 10.3390/polym14040707
Hayden PJ, Roddie C, Bader P, Basak GW, Bonig H, Bonini C, Chabannon C, Ciceri F, Corbacioglu S, Ellard R, Sanchez-Guijo F, Jäger U, Hildebrandt M, Hudecek M, Kersten MJ, Köhl U, Kuball J, Mielke S, Mohty M, Murray J, Nagler A, Rees J, Rioufol C, Saccardi R, Snowden JA, Styczynski J, Subklewe M, Thieblemont C, Topp M, Ispizua ÁU, Chen D, Vrhovac R, Gribben JG, Kröger N, Einsele H, Yakoub-Agha I. Management of adults and children receiving CAR T-cell therapy: 2021 best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA). Ann Oncol. 2022 Mar;33(3):259-275. doi: 10.1016/j.annonc.2021.12.003. Epub 2021 Dec 16
Heggli I, Blache U, Herger N, Mengis T, Jaeger PK, Schupbach R, Farshad-Amacker N, Brunner F, Snedeker JG, Farshad M, Distler O, Dudlis S. FGF2 overrides key pro-fibrotic features of bone marrow stromal cells isolated from Modic type 1 change patients. Eur Cell Mater. 2022 Oct 18;44:101-114. doi: 10.22203/eCM.v044a07
Hoen L, Rudisch C, Wick M, Indenbirken M, Grundhoff A, Wegwitz F, Kalkhof S, Hildebrand J. Osmotic stress interferes with DNA damage response and H2AX phosphorylation in human keratinocytes. Cells. 2022 Mar 11;11(6):959. doi: 10.3390/cells11060959
Hofrichter J, Sempert K, Kerkhoff C, Breitrueck A, Wasserkort R, Mitzner S. Phosphate restriction using a processed clay mineral reduces vascular pathologies and microalbuminuria in rats with chronic renal failure. BMC Nephrol. 2022 Apr 28;23(1):162. doi: 10.1186/s12882-022-02743-5
Hunger R, Seliger B, Ogino S, Mantke R. Mortality factors in pancreatic surgery: A systematic review. How important is the hospital volume? Int J Surg. 2022 May;101:106640. doi: 10.1016/j.ijsu.2022.106640. Epub 2022 May 4
Ilse V, Scholz R, Wermann M, Naumann M, Staege M S, Roßner S, Cynis H. Immunogenicity of the envelope surface unit of human endogenous retrovirus K18 in mice. Int J Mol Sci. 2022 Jul 28;23(15):8330. doi: 10.3390/ijms23158330
Issmail L, Möser C, Jäger C, Altattan B, Ramsbeck D, Kleinschmidt M, Buchholz M, Smith D, Grunwald T. Prefusion-specific antibody-derived peptides trivalently presented on DNA-nanoscaffolds as an innovative strategy against RSV entry. Frontiers in Virology (2022). doi: 10.3389/fviro.2022.994843
Itani M I, Oberbach A, Salimian K J, Enderle M, Hahn H, Abbarh S, Kendrick K, Schlichting N, Anders R A, Besharati S, Farha J, Fayad L, Kalloo A N, Badurdeen D, Kumbhari V. Gastric mucosal devitalization (GMD): using the porcine model to develop a novel endoscopic bariatric approach. Obes Surg. 2022 Feb;32(2):381-390. doi: 10.1007/s11695-021-05773-4. Epub 2021 Nov 19
Jasinski-Bergner S, Bluemke J, Bauer M, Skiebe S L, Mandelboim O, Wickenhauser C, Seliger B. Novel approach to identify putative Epstein–Barr–virus microRNAs regulating host cell genes with relevance in tumor biology and immunology. Oncoimmunology. 2022 May 1;11(1):2070338. doi: 10.1080/2162402X.2022.2070338. eCollection 2022
Jasinski-Bergner S, Eckstein M, Taubert H, Wach S, Fiebig C, Strick R, Hartmann A, Seliger B. The human leukocyte antigen G as an immune escape mechanism and novel therapeutic target in urological tumors. Front Immunol. 2022 Feb 3;13:811200. doi: 10.3389/fimmu.2022.811200. eCollection 2022
Jasinski-Bergner S, Schmiedel D, Mandelboim O, Seliger B. Role of HLA-G in viral infections. Front Immunol. 2022 Feb 14;13:826074. doi: 10.3389/fimmu.2022.826074. eCollection 2022
Jiao Z, Han Y, Zhao J, Chao Z, Tárnok A, You Z. Rapid switching and durable on-chip spark-cavitation-bubble cell sorter. Microsyst Nanoeng. 2022 May 18;8:52. doi: 10.1038/s41378-022-00382-2. eCollection 2022
Kaniowska D, Wenk K, Rademacher P, Weiss R, Fabian C, Schulz I, Guthardt M, Lange F, Greiser S, Schmidt M, Braumann U-D, Emmrich F, Koehl U, Jaimes Y. Extracellular Vesicles of Mesenchymal Stromal Cells Can be Taken Up by Microglial Cells and Partially Prevent the Stimulation Induced by β-amyloid Stem Cell. Rev Rep. 2022 Mar;18(3):1113-1126. doi: 10.1007/s12015-021-10261-4. Epub 2022 Jan 26
Klinkmann G, Wild T, Heskamp B, Doss F, Doss S, Arseniev L, Aleksandrova K, Sauer M, Reuter D A, Mitzner S, Altrichter J. Extracorporeal immune cell therapy of sepsis: ex vivo results. Intensive Care Med Exp. 2022 Jun 16;10(1):26. doi: 10.1186/s40635-022-00453-8
Klose J, Griehl C, Roßner S, Schilling S. Natural products from plants and algae for treatment of Alzheimer’s disease: a review. Biomolecules. 2022 May 12;12(5):694. doi: 10.3390/biom12050694
Kruse M, Altattan B, Laux E-M, Grasse N, Heinig L, Moeser C, Smith D M, Hoelzel R. Characterization of binding interactions of SARS-CoV-2 spike protein and DNA-peptide nanostructures. Sci Rep. 2022 Jul 27;12(1):12828. doi: 10.1038/s41598-022-16914-9
Kruse M, Moeser C, Smith D M, Mueller-Landau H, Rant U, Hoelzel R, Bier F F. Measuring Influenza A virus and peptide interaction using electrically controllable DNA nanolevers. Advanced materials technologies 7 (2022), 5, 2101141, 11 Seiten. doi: 10.1002/admt.202101141
Leptihn S, Loh B W-C. Complexity, challenges and costs of implementing phage therapy. Future Microbiol. 2022 Jun;17:643-646. doi: 10.2217/fmb-2022-0054. Epub 2022 Apr 11
Liu M, Tian Y, Zaki H E M, Ahmed T, Yao R, Yan C, Leptihnm S, Loh B, Shahid M S, Wang F, Chen J, Li B. Phage resistance reduced the pathogenicity of Xanthomonas oryzae pv. oryzae on rice. Viruses. 2022 Aug 13;14(8):1770. doi: 10.3390/v14081770
Liu Y, Wang S, Schubert M-L, Lauk A, Yao H, Blank M F, Cui C, Janssen M, Schmidt C, Göllner S, Kleist C, Zhou F, Rahfeld J-U, Sauer T, Schmitt M, Mueller-Tidow C. CD33-directed immunotherapy with third-generation chimericantigen receptor T cells and gemtuzumab ozogamicin in intactand CD33-edited acute myeloid leukemia and hematopoieticstem and progenitor cells. Int J Cancer. 2022 Apr 1;150(7):1141-1155. doi: 10.1002/ijc.33865. Epub 2021 Nov 23
Loeffler-Wirth H, Kreuz M, Schmidt M, Ott G, Siebert R, Binder H. Classifying germinal center derived lymphomas - navigate a complex transcriptional landscape. Cancers (Basel). 2022 Jul 14;14(14):3434. doi: 10.3390/cancers14143434
Loeffler-Wirth H, Rade M, Arakelyan A, Kreuz M, Loeffler M, Koehl U, Reiche K, Binder H. Transcriptional states of CAR-T infusion relate to neurotoxicity - lessons from high-resolution single-cell SOM expression portraying. Front Immunol. 2022 Sep 28;13:994885. doi: 10.3389/fimmu.2022.994885. eCollection 2022
Manohar P, Loganathan A, Nachimuthu R, Loh B, Ma L, Turner D, Leptihn S. Complete Genome Sequence of Pseudomonas Phage Motto. Microbiol Resour Announc. 2022 Nov 17;11(11):e0074022. doi: 10.1128/mra.00740-22. Epub 2022 Oct 12
Massa C, Seliger B. Enhanced function of vaccine dendritic cells from obese donors upon inhibition of the lipid metabolism. Clin Transl Med. 2022 Feb;12(2):e557. doi: 10.1002/ctm2.557
Nachimuthu R, Manohar P, Eniyan K, Archana L, Athira S, Loh B, Ma L, Leptihn S. A lysozyme murein hydrolase with broad-spectrum antibacterial activity from Enterobacter phage myPSH1140. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0050622. doi: 10.1128/aac.00506-22. Epub 2022 Aug 11
Nagel M, Moretti R, Paschke R, Bergen M, Meiler J, Kalkhof S. Integrative model of the FSH receptor reveals the structural role of the flexible hinge region. Structure. 2022 Oct 6;30(10):1424-1431.e3. doi: 10.1016/j.str.2022.07.007. Epub 2022 Aug 15
Nickel O, Rockstroh A, Borte S, Wolf J. Evaluation of simple lateral flow immunoassays for detection of SARS-CoV-2 neutralizing antibodies. Vaccines (Basel). 2022 Feb 23;10(3):347. doi: 10.3390/vaccines10030347
Nickel O, Rockstroh A, Wolf J, Landgraf S, Kalbitz S, Kellner N, Borte M, Pietsch C, Fertey J, Lübbert C, Ulbert S, Borte S. Evaluation of the systemic and mucosal immune response induced by COVID-19 and the BNT162b2 mRNA vaccine for SARS-CoV-2. PLoS One. 2022 Oct 18;17(10):e0263861. doi: 10.1371/journal.pone.0263861. eCollection 2022
Oberbach A, Schlichting N, Hagl C, Lehmann S, Kullnick Y, Friedrich M, Köhl U, Horn F, Kumbhari V, Löffler B, Schmidt F, Joskowiak D, Born F, Saha S, Bagaev E. Four decades of experience of prosthetic valve endocarditis reflect a high variety of diverse pathogens. Cardiovasc Res. 2022 Apr 14;cvac055. doi: 10.1093/cvr/cvac055. Online ahead of print
Peter A S, Roth E, Schulz S R, Fraedrich K, Steinmetz T, Damm D, Hauke M, Richel E, Mueller-Schmucker S, Habenicht K, Eberlein V, Issmail L, Uhlig N, Dolles S, Gruener E, Peterhoff D, Ciesek S, Hoffmann M H, Poehlmann S, McKay P F, Shattock R J, Woelfel R, Socher E, Wagner R, Eichler J, Sticht H, Schuh W, Neipel F, Ensser A, Mielenz D, Tenbusch M, Winkler T H, Grunwald T, Überla K, Jäck H-M. A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model. Eur J Immunol. 2022 May;52(5):770-783. doi: 10.1002/eji.202149374. Epub 2021 Sep 13
Poh P S, Lingner T, Kalkhof S, Maerdian S, Baumbach J, Dondl P, Duda G N, Checa S. Enabling technologies towards personalization of scaffolds for large bone defect regeneration. Curr Opin Biotechnol. 2022 Apr;74:263-270. doi: 10.1016/j.copbio.2021.12.002. Epub 2022 Jan 7
Ramírez Caballero L, Treudler R,Delaroque N, Simon J C, Kern K, Szardenings M. Peptide epitopes as biomarkers of soya sensitization in rBet v 1 immunotherapy of birch‐related soya allergy. Clin Exp Allergy. 2022 Sep 14. doi: 10.1111/cea.14224. Online ahead of print
Reiber M, Koska I, Pace C, Schoenhoff K, Schumann L von, Palme R, Potschka H. Development of behavioral patterns in young C57BL/6J mice: a home cage-based study. Sci Rep. 2022 Feb 15;12(1):2550. doi: 10.1038/s41598-022-06395-1
Richter A, Seidel R W, Goddard R, Eckhardt T, Lehmann C, Doerner J, Siersleben F, Sondermann T, Mann L, Patzer M, Jaeger C, Reiling N, Imming P. BTZ-derived benzisothiazolinones with in vitro activity against mycobacterium tuberculosis. ACS Med Chem Lett. 2022 Jul 25;13(8):1302-1310. doi: 10.1021/acsmedchemlett.2c00215. eCollection 2022 Aug 11
Riester O, Burkhardtsmaier P, Gurung Y, Laufer S, Deigner H-P, Schmidt M S. Synergy of R-(-)carvone and cyclohexenone-based carbasugar precursors with antibiotics to enhance antibiotic potency and inhibit biofilm formation. Sci Rep. 2022 Oct 26;12(1):18019. doi: 10.1038/s41598-022-22807-8
Ritter P, Cai A, Reischl B, Fiedler M, Prols G, Fries B, Kretzschmar E, Michael M, Hartmann K, Lesko C, Salti H, Arkudas A, Horch R, Paulsen F, Friedrich O, Haug M. MyoBio: an automated bioreactor system technology for standardized perfusion-decellularization of whole skeletal muscle. IEEE Trans Biomed Eng. 2022 Jul;69(7):2305-2313. doi: 10.1109/TBME.2022.3142317. Epub 2022 Jun 17
Ruppel K, Fricke S, Koehl U, Schmiedel D. Taking lessons from CAR-T cells and going beyond: tailoring design and signaling for CAR-NK cells in cancer therapy. Front Immunol. 2022 Mar 18;13:822298. doi: 10.3389/fimmu.2022.822298. eCollection 2022
Saha S, Ali A, Schnackenburg P, Horke K M, Oberbach A, Schlichting N, Sadoni S, Rizas K, Braun D, Luehr M, Bagaev E, Hagl C, Joskowiak D. Surgery for aortic prosthetic valve endocarditis in the transcatheter era. J Clin Med. 2022 Jun 14;11(12):3418. doi: 10.3390/jcm11123418
Saliba F, Bañaras R, Larsen F S, Wilmer A, Parés A, Mitzner S, Stange J, Fuhrmann V, Gilg S, Hassanein T, Samuel D, Torner J, Jaber S. Artificial liver support in patients with liver failure: a modified DELPHI consensus of international experts. Intensive Care Med. 2022 Oct;48(10):1352-1367. doi: 10.1007/s00134-022-06802-1. Epub 2022 Sep 6
Schaffert A, Karkossa I, Ueberham E, Schlichting R, Walter K, Arnold J, Blüher M, Heiker J T, Lehmann J, Wabitsch M, Escher B I, Bergen M, Schubert K. Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes. Environ Int. 2022 Jun;164:107279. doi: 10.1016/j.envint.2022.107279. Epub 2022 May 6
Schary W, Paskali F, Rentschler S, Ruppert C, Wagner G E, Steinmetz I, Deigner H-P, Kohl M. Open-source, adaptable, all-in-one smartphone-based system for quantitative analysis of point-of-care diagnostics. Diagnostics (Basel). 2022 Feb 25;12(3):589. doi: 10.3390/diagnostics12030589
Schilling E, Pfeiffer L, Hauschildt S, Koehl U, Claus C. CD14 Is involved in the Interferon response of human macrophages to Rubella virus infection. Biomedicines. 2022 Jan 26;10(2):266. doi: 10.3390/biomedicines10020266
Seliger B, Al-Samadi A, Yang B, Salo T, Wickenhauser C. In vitro models as tools for screening treatment options of head and neck cancer. Front Med (Lausanne). 2022 Sep 7;9:971726. doi: 10.3389/fmed.2022.971726. eCollection 2022
Seliger B, Jasinski-Bergner S, Massa C, Mueller A, Biehl K, Yang B, Bachmann M, Jonigk D, Eichhorn P, Hartmann A, Wickenhauser C, Bauer M. Induction of pulmonary HLA-G expression by SARS-CoV-2 infection. Cell Mol Life Sci. 2022 Nov 5;79(11):582. doi: 10.1007/s00018-022-04592-9
Seliger B, Koehl U. Underlying mechanisms of evasion from NK cells as rationale for improvement of NK cell-based immunotherapies. Front Immunol. 2022 Aug 12;13:910595. doi: 10.3389/fimmu.2022.910595. eCollection 2022
Seliger B, Massa C. Modulation of lymphocyte functions in the microenvironment by tumor oncogenic pathways. Front Immunol. 2022 May 19;13:883639. doi: 10.3389/fimmu.2022.883639. eCollection 2022
Semwala R, Semwal R B, Lehmann J, Semwal D K. Recent advances in immunotoxicity and its impact on human health: causative agents, effects and existing treatments. Int Immunopharmacol. 2022 Jul;108:108859. doi: 10.1016/j.intimp.2022.108859. Epub 2022 May 19
Spukti F F, Schnauß J. Large and stable: actin aster networks formed via entropic forces. Front Chem. 2022 Aug 25;10:899478. doi: 10.3389/fchem.2022.899478. eCollection 2022
Stegmann K M, Dickmanns A, Heinen N, Blaurock C, Karrasch T, Breithaupt A, Klopffleisch R, Uhlig N, Eberlein V, Issmail L, Herrmann S T, Schreieck A, Peelen E, Kohlhof H, Sadeghi B, Riek A, Speakman J R, Groß U, Goerlich D, Vitt D, Mueller T, Grunwald T, Pfaender S, Balkema-Buschmann A, Dobbelstein M. Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication. iScience. 2022 May 20;25(5):104293. doi: 10.1016/j.isci.2022.104293. Epub 2022 Apr 25
Strobelt R, Adler J, Paran N, Yahalom-Ronen Y, Melamed S, Politi B, Shulman Z, Schmiedel D, Shaul Y. Imatinib inhibits SARS-CoV-2 infection by an off-target-mechanism. Sci Rep. 2022 Apr 6;12(1):5758. doi: 10.1038/s41598-022-09664-1
Subbarayan K, Massa C, Leisz S, Steven A, Bethmann D, Biehl K, Wickenhauser C, Seliger B. Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells. Oncoimmunology. 2022 Apr 28;11(1):2069214. doi: 10.1080/2162402X.2022.2069214. eCollection 2022
Subirana M A, Riemschneider S, Hause G, Dobritzsch D, Schaumloeffel D, Herzberg M. High spatial resolution imaging of subcellular macro and trace element distribution during phagocytosis. Metallomics. 2022 Apr 1;14(4):mfac011. doi: 10.1093/mtomcs/mfac011
Taha A, Bobi J, Dammers R, Dijkhuizen R M, Dreyer A Y, Es A C G M, Ferrara F, Gounis M J, Nitzsche B, Platt S, Stoffel M H, Volovici V, Zoppo G J, Duncker D J, Dippel D W J, Boltze J, Beusekom H M M. Comparison of large animal models for acute ischemic stroke: which model to use? Stroke. 2022 Apr;53(4):1411-1422. doi: 10.1161/STROKEAHA.121.036050. Epub 2022 Feb 15
Toma G, Karapetian E, Massa C, Quandt D, Seliger B. Characterization of the effect of histone deacetylation inhibitors on CD8+ T cells in the context of aging. J Transl Med. 2022 Nov 22;20(1):539. doi: 10.1186/s12967-022-03733-9
Toma G, Lemnian IM, Karapetian E, Grosse I, Seliger B. Transcriptional Analysis of Total CD8+ T Cells and CD8+CD45RA- Memory T Cells From Young and Old Healthy Blood Donors. Front Immunol. 2022 Jan 27;13:806906. doi: 10.3389/fimmu.2022.806906. eCollection 2022
Wagner D L, Koehl U, Chmielewski M, Scheid C, Stripecke R. Review: sustainable clinical development of CAR-T cells - switching from viral transduction towards CRISPR-Cas gene editing. Front Immunol. 2022 Jun 17;13:865424. doi: 10.3389/fimmu.2022.865424. eCollection 2022
Weil T, Kirupakaran A, Le M-H, Rebmann P, Mieres-Perez J, Issmail L, Conzelmann C, Mueller J A, Rauch L, Gilg A, Wettstein L, Groß R, Read C, Bergner T, Axberg Pålsson S, Uhlig N, Eberlein V, Woell H, Klaerner F-G, Stenger S, Kuemmerer B M, Streeck H, Fois G, Frick M, Braubach P, Spetz A-L, Grunwald T, Shorter J, Sanchez-Garcia E, Schrader T, Muench J. Advanced molecular tweezers with lipid anchors against SARS-CoV-2 and other respiratory viruses. JACS Au. 2022 Sep 6;2(9):2187-2202. doi: 10.1021/jacsau.2c00220. eCollection 2022 Sep 26
Werner M, Dyas A, Parfentev I, Schmidt G E, Mieczkowska I K, Mueller-Kirschbaum L C, Mueller C, Kalkhof S, Reinhardt O, Urlaub H, Alves F, Gallwas J, Prokakis E, Wegwitz F. ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness. Cell Death Dis. 2022 Sep 3;13(9):762. doi: 10.1038/s41419-022-05197-7
Zhang L, Wang X, Hua X, Yu Y, Lepthin S, Loh B. Therapeutic evaluation of the Acinetobacter baumannii phage Phab24 for clinical use. Virus Res. 2022 Oct 15;320:198889. doi: 10.1016/j.virusres.2022.198889. Epub 2022 Aug 12

Publikationen 2021

Ahlhelm M, Latorre S H, Mayr H O, Storch C, Freytag C, Werner D, Schwarzer-Fischer E, Seidenstücker M. Mechanically stable β-TCP structural hybrid scaffolds for potential bone replacement. J. Compos. Sci. 5 (2021), 10, 281. doi: 10.3390/jcs5100281
Allelein S, Medina-Perez P, Heitor Lopes A L, Rau S, Hause G, Kölsch A, Kuhlmeier D. Potential and challenges of specifically isolating extracellular vesicles from heterogeneous populations. Sci Rep. (2021) , 11, 11585. doi: 10.1038/s41598-021-91129-y
Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H, Jassoy C. A review of the toxicity and phytochemistry of Medicinal plant species used by herbalists in treating people living with HIV/AIDS in Uganda. Front Pharmacol. (2021), 12, 615147. doi: 10.3389/fphar.2021.615147
Bauer M, Vaxevanis C, Al-Ali H K, Jaekel N, Le Hoa Naumann C, Schaffrath J, Rau A, Seliger B, Wickenhauser C. Altered spatial composition of the immune cell repertoire in association to CD34+ blasts in myelodysplastic syndromes and secondary acute myeloid leukemia. Cancers (Basel).13 (2021), 2, 186. doi: 10.3390/cancers13020186
Berneck BS, Rockstroh A, Barzon L, Sinigaglia A, Vocale C, Landini MP, Rabenau HF, Schmidt-Chanasit J, Ulbert S. Serological differentiation of West Nile virus- and Usutu virus-induced antibodies by envelope proteins with modified cross-reactive epitopes. Transbound Emerg Dis. (2021) Dec 16. doi: 10.1111/tbed.14429
Berto C, Krajcarz M T, Hoyo M, Komar M, Sinet-Mathiot V, Zarzecka-Szubinska K, Krajcarz M, Szymanek M, Wertz K, Marciszak A, Metrak M, Suska-Malawska M, Wilcke A, Kot M. Environment changes during middle to upper palaeolithic transition in southern Poland (Central Europe) : a multiproxy approach for the MIS 3 sequence of Koziarnia Cave (Kraków-Częstochowa Upland). Journal of archaeological science reports 35 (2021), 102723. doi: 10.1016/j.jasrep.2020.102723
Bialek-Waldmann JK, Domning S, Esser R, Glienke W, Mertens M, Aleksandrova K, Arseniev L, Kumar S, Schneider A, Koenig J, Theobald SJ, Tsay HC, Cornelius ADA, Bonifacius A, Eiz-Vesper B, Figueiredo C, Schaudien D, Talbot SR, Bleich A, Spineli LM, von Kaisenberg C, Clark C, Blasczyk R, Heuser M, Ganser A, Köhl U, Farzaneh F, Stripecke R. Induced dendritic cells co-expressing GM-CSF/IFN-α/tWT1 priming T and B cells and automated manufacturing to boost GvL. Mol Ther Methods Clin Dev. (2021) 21, Seite 621-641. doi: 10.1016/j.omtm.2021.04.004
Binder S, Zipfel I, Müller C, Wiedemann K, Schimmelpfennig C, Pfeifer G, Reiche K, Hauschildt S, Lehmann J, Köhl U, Horn F, Friedrich M. The noncoding RNA LINC00152 conveys contradicting effects in different glioblastoma cells. Sci Rep. (2021), 11, 18499. doi: 10.1038/s41598-021-97533-8
Bitar M, Boettcher M, Boldt A, Hauck F, Köhl U, Liebert UG, Magg T, Schulz MS, Sack U. Flow cytometric measurement of STAT5 phosphorylation in cytomegalovirus-stimulated T cells. Cytometry A. 99 (2021), 8, Seite 774-783. doi: 10.1002/cyto.a.24286
Blache U, Weiss R, Boldt A, Kapinsky M, Blaudszun AR, Quaiser A, Pohl A, Miloud T, Burgaud M, Vucinic V, Platzbecker U, Sack U, Fricke S, Koehl U. Advanced flow cytometry assays for immune monitoring of CAR-T cell applications. Front Immunol. (2021), 12, 658314. doi: 10.3389/fimmu.2021.658314
Blaess M, Kaiser L, Sommerfeld O, Csuk R, Deigner H-P. Drugs, metabolites, and lung accumulating small lysosomotropic molecules: multiple targeting impedes SARS-CoV-2 infection and progress to COVID-19. Int J Mol Sci. 22 (2021), 4, 1797. doi: 10.3390/ijms22041797
Bluhm A, Schrempel S, Hörsten S, Schulze A, Roßner S. Proteolytic α-synuclein cleavage in health and disease. Int J Mol Sci. 22, (2021), 11, 5450. doi: 10.3390/ijms22115450
Breitrück A, Weigel M, Hofrichter J, Sempert K, Kerkhoff C, Mohebali N, Mitzner S, Hain T, Kreikemeyer B. Smectite as a preventive oral treatment to reduce clinical symptoms of DSS induced colitis in Balb/c mice. Int J Mol Sci. 22 (2021), 16, 8699. doi: 10.3390/ijms22168699
Büning H, Fehse B, Ivics Z, Kochanek S, Koehl U, Kupatt C, Mussolino C, Nettelbeck DM, Schambach A, Uckert W, Wagner E, Cathomen T. Gene therapy "Made in Germany": a historical perspective, analysis of the status quo, and recommendations for action by the German Society for Gene Therapy. Hum Gene Ther. 32 (2021), 19-20, Seite 987-996. doi: 10.1089/hum.2021.29178.hbu
de Maat S, Clark C, Barendrecht AD, Smits S, van Kleef ND, El Otmani H, Waning M, van Moorsel MVA, Szardenings M, Delaroque N, Vercruysse K, Urbanus RT, Sebastian S, Lenting PJ, Hagemeyer CE, Renné T, Vanhoorelbeke K, Tersteeg C, Maas C. Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis. Blood (2021), Nov 9. doi: 10.1182/blood.2021011776
Dekker J, Sinet-Mathiot V, Spithoven M, Smit B, Wilcke A, Welker F, Verpoorte A, Soressi M. Human and cervid osseous materials used for barbed point manufacture in Mesolithic Doggerland. Journal of archaeological science reports 35 (2021), 102678, 9 Seiten. doi: 10.1016/j.jasrep.2020.102678
Dorner J, Korn P, Gruhle K, Ramsbeck D, Garamus VM, Lilie H, Meister A, Schwieger C, Ihling C, Sinz A, Drescher S. A diazirine-modified membrane lipid to study peptide/lipid interactions - chances and challenges. Chemistry. 27 (2021), 59, Seite 14586-14593. doi: 10.1002/chem.202102048
Elbalasy I, Mollenkopf P, Tutmarc C, Herrmann H, Schnauß J. Keratins determine network stress responsiveness in reconstituted actin-keratin filament systems. Soft Matter. 17 (2021), 14, Seite 3954-3962. doi: 10.1039/d0sm02261f
Engel K, Wieland L, Krüger A, Volkmer I, Cynis H, Emmer A, Staege MS. Identification of differentially expressed human endogenous retrovirus families in human leukemia and lymphoma cell lines and stem cells. Front Oncol. (2021), 11, 637981. doi: 10.3389/fonc.2021.637981
Evert K, Kocher T, Schindler A, Müller M, Müller K, Pink C, Holtfreter B, Schmidt A, Dombrowksi F, Schubert A, Woedtke T, Rupf S, Calvisi D F, Bekeschuss S, Jablonowski L. Repeated exposure of the oral mucosa over 12 months with cold plasma is not carcinogenic in mice. Sci Rep. (2021), 11, 1, 20672. doi: 10.1038/s41598-021-99924-3
Galbraith D, Loureiro J, Antoniadi I, Bainard J,Bures P, Cápal P, Castro M, Castro S, Certner M, Certnerova D, Chumova Z, Dolezel J, Giorgi D, Husband B C, Kolár F, Koutecký P, Kron P, Leitch I J, Ljung K, Lopes S, Lucanova M, Lucretti S, Ma W, Melzer S, Molnár I, Novák O, Poulton N, Skalický V, Sliwinska E, Smarda P, Smith T W, Sun G, Talhinhas P, Tárnok A, Temsch E M, Trávnícek P, Urfus T. Best practices in plant cytometry. Cytometry A. 99 (2021), 4, Seite 311-317. doi: 10.1002/cyto.a.24295
Gege C, Bravo F J.; Uhlig N, Hagmaier T, Schmachtenberg R, Elis J, Burger-Kentischer A, Finkelmeier D, Hamprecht K, Grunwald T, Bernstein D I, Kleymann G. A helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections. Sci Transl Med. 13 (2021), 598, eabf8668. doi: 10.1126/scitranslmed.abf8668
Glaser M, Deb S, Seier F, Agrawal A, Liedl T, Douglas S, Gupta M K, Smith DM. The art of designing DNA nanostructures with CAD software. Molecules. 26 (2021), 8, 2287. doi: 10.3390/molecules26082287
Gragoll I, Schumann L, Neubauer M, Westphal C, Lang H. Healthcare avoidance: a qualitative study of dental care avoidance in Germany in terms of emergent behaviours and characteristics. BMC Oral Health. 21 (2021), 1, 563. doi: 10.1186/s12903-021-01933-1
Gröger V, Emmer A, Staege MS, Cynis H. Endogenous retroviruses in nervous system disorders. Pharmaceuticals (Basel) 14 (2021), 1, 70. doi: 10.3390/ph14010070
Häfner L, Kalkhof S, Jira W. Authentication of nine poultry species using high-performance liquid chromatography–tandem mass spectrometry. Food control 122 (2021), 10780. doi: 10.1016/j.foodcont.2020.107803
Hansen M, Stahl L, Heider A, Hilger N, Sack U, Kirschner A, Cross M, Fricke S. Reduction of graft-versus-host-disease in NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice by cotransplantation of syngeneic human umbilical cord-derived mesenchymal stromal cells. Transplant Cell Ther. 27 (2021), 8, 658, e1-658.e10. doi: 10.1016/j.jtct.2021.04.018
Haq Z, Itani M I, Zhang L, Dinary F, Farha J, Abbarh S, Akshintala V, Koller K, Jovani M, Hedjoudje A, Ngamruengphong S, Oberbach A, Badurdeen D, Kumbhari V. The utility of EndoFLIP for measuring gastrojejunal anastomosis diameter and distensibility in patients experiencing weight regain post Roux-en-Y gastric bypass. Obes Surg. (2021), 7, Seite 3353-3359. doi: 10.1007/s11695-021-05302-3
Hartlage-Rübsamen M, Bluhm A, Moceri S, Machner L, Köppen J, Schenk M, Hilbrich I, Holzer M, Weidenfeller M, Richter F, Coras R, Serrano G E , Beach T G , Schilling S, von Hörsten S, Xiang W, Schulze A, Roßner S. A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies. Acta neuropathologica (2021), 142 (3), S. 399–421. doi: 10.1007/s00401-021-02349-5
Häusner S, Herbst L, Bittorf P, Schwarz T, Henze C, Mauermann M, Ochs J, Schmitt R, Blache U, Wixmerten A, Miot S, Martin I, Pullig O. From single batch to mass-production-automated platform design concept for a phase II clinical trial tissue engineered cartilage product. Front Med (Lausanne). (2021), 8, 712917. doi: 10.3389/fmed.2021.712917
Hoen L, Pfeffer D, Zapf R, Raabe A, Hildebrand J, Kraft J, Kalkhof S. Association of drug application and hydration status in elderly patients. Nutrients. 13 (2021), 6, 1929. doi: 10.3390/nu13061929
Hoffmann T, Rahfeld J-U, Schenk M, Ponath F, Makioka K, Hutter-Paier B, Lues I, Lemere C, Schilling S. Combination of the glutaminyl cyclase inhibitor PQ912 (Varoglutamstat) and the murine monoclonal antibody PBD-C06 (m6) shows additive effects on brain Aβ pathology in transgenic mice. Int J Mol Sci. 22 (2021), 21, 11791. doi: 10.3390/ijms222111791
Hoyer S, Eberlein V, Schuler G, Berking C, Heinzerling L, Schaft N, Dörrie J. BRAF and MEK inhibitors affect dendritic-cell maturation and t-cell stimulation. Int J Mol Sci. 22 (2021), 21, 11951. doi: 10.3390/ijms222111951
Huber R, Augsten S, Kirsten H, Zell R, Stelzner A, Thude H, Eidner T, Stuhlmüller B, Ahnert P, Kinne RW. Identification of new, functionally relevant mutations in the coding regions of the human fos and jun proto-oncogenes in rheumatoid arthritis synovial tissue. Life 11 (2021), 5. doi: 10.3390/life11010005
Kitte R, Tretbar M, Dluczek S, Beckmann L, Marquardt P, Duenkel A, Schubert A, Fricke S, Tretbar US. Chemical and cytotoxic activity of three main sesquiterpenoids from Warburgia ugandensis. Results in Chemistry (2021), 3, 100242. doi: 10.1016/j.rechem.2021.100242
Koball S, Westphal C, Frimmel S, Hinz M, Klammt S, Mitzner S. Comparison of changes in albumin binding capacity during hemodiafiltration or hemodialysis with middle cut off membranes. Int J Artif Organs 44 (2021), 5, Seite 297-301. doi: 10.1177/0391398820961780
Köhl U, Abken H. CAR T cells as drugs for novel therapies (advanced therapy medicinal products). Internist 62 (2021), 4 Seite 449-457. doi: 10.1007/s00108-021-00953-x
Koliopoulos P, Kayange N M, Daniel T, Huth F, Gröndahl B, Medina-Montaño G C, Pretsch L, Klüber J, Schmidt C, Züchner A, Ulbert S, Mshana S E, Addo M, Gehring S. Multiplex-RT-PCR-ELISA panel for detecting mosquito-borne pathogens: plasmodium sp. preserved and eluted from dried blood spots on sample cards. Malar J. 20 (2021), 1, 66. doi: 10.1186/s12936-021-03595-4
Körner S, Makert GR, Ulbert S, Pfeffer M, Mertens-Scholz K. The prevalence of Coxiella burnetii in hard ticks in Europe and their role in Q fever transmission revisited - a systematic review. Front Vet Sci. (2021), 8:655715. doi: 10.3389/fvets.2021.655715
Körtge A, Majcher-Peszynska J, Heskamp B, Wasserkort R, Mitzner S. Antibiotics removal by continuous venovenous hemofiltration with a novel asymmetric triacetate membrane hemofilter: an in vitro study. Blood Purif. 50 (2021), 6, Seite 899-905. doi: 10.1159/000513417
Krüsemann H, Töllner P, Westphal E, Hofrichter J, Seitz H. Design and 3D printing of miniaturized dialyzers for laboratory use. Transactions AMM 3 (2021), 1, 545. doi: 10.18416/AMMM.2021.2109545
Kürzel S, Blaudszun A-R, Stahl L, Herbst R, Krochinsky F, Birkmann J, Hänel A, Schäfer-Eckart K, Ehninger G, Fiedler F, Bornhäuser M , Fricke S, Hänel M. Dexa-BEAM versus MIFAP as salvage regimen for recurrent lymphoma: a prospective randomized multicenter phase II trial with a median follow-up of 14.4 years. J Cancer Res Clin Oncol. (2021), doi: 10.1007/s00432-021-03702-7
Langerak T, Kasbergen LMR, Chandler F, Brinkman T, Faerber Z, Phalai K, Ulbert S, Rockstroh A, Bruin E de, Koopmans MPG, Rockx B, Gorp ECM van, E, Vreden S. Zika virus antibody titers three years after confirmed infection. Viruses (2021), 13, 7, 1345. doi: 10.3390/v13071345
Lapuente D, Fuchs J, Willar J, Antão AV, Eberlein V, Uhlig N, Issmail L, Schmidt A, Oltmanns F, Peter AS,Mueller-Schmucker S, Irrgang P, Fraedrich K, Cara A, Hoffmann M, Pöhlmann S, Ensser A, Pertl C, Willert T, Thirion C, Grunwald T, Überla K, Tenbusch M. Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization. Nat Commun. (2021), 12, 1, 6871. doi: 10.1038/s41467-021-27063-4
Laube M, Pietsch S, Pannicke T, Thome UH, Fabian C. Development and functional characterization of fetal lung organoids. Front Med (Lausanne) (2021), 8, 678438. doi: 10.3389/fmed.2021.678438
Lidzba N, Arteaga V G, Schiermeyer A, Havenith H, Muranyi I, Schillberg S, Lehmann J, Ueberham E. Development of monoclonal antibodies against pea globulins for multiplex assays targeting legume proteins. J Agric Food Chem. 69 (2021), 9, Seite 2864-2874. doi: 10.1021/acs.jafc.0c07177
Linnert M, Fritz C, Jäger C, Schlenzig D, Ramsbeck D, Kleinschmidt M, Wermann M, Demuth HU, Parthier C, Schilling S. Structure and dynamics of Meprin β in complex with a hydroxamate-based inhibitor. Int J Mol Sci. 22 (2021), 11, 5651. doi: 10.3390/ijms22115651
Mahmoud M, Ruppert C, Rentschler S, Laufer S, Deigner H-P. Combining aptamers and antibodies: lateral flow quantification for thrombin and interleukin-6 with smartphone readout. Sensors and actuators. B, chemical 333 (2021), 129246. doi: 10.1016/j.snb.2020.129246
Meir A Y, Keller M, Bernhart S H, Rinott E, Tsaban G, Zelicha H, Kaplan A, Schwarzfuchs D, Shelef I, Gepner Y, Li Y, Lin Y, Blüher M, Ceglarek U, Stumvoll M, Stadler P F, Stampfer M J, Kovacs P, Liang L , Shai I. Lifestyle weight-loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial. Clin Epigenetics 13 (2021), 1, 48. doi: 10.1186/s13148-021-01038-0
Meir A Y, Keller M, Müller L, Bernhart S H, Tsaban G, Zelicha H, Rinott E, Kaplan A, Gepner Y, Shelef I, Schwarzfuchs D, Ceglarek U, Stadler P F, Blüher M, Stumvoll M, Kovacs P, Shai I. Effects of lifestyle interventions on epigenetic signatures of liver fat: Central randomized controlled trial. Liver Int. 41 (2021), 9, Seite 2101-2111. doi: 10.1111/liv.14916
Meyer S, Handke D, Mueller A, Biehl K, Kreuz M, Bukur J, Koehl U, Lazaridou MF, Berneburg M, Steven A, Massa C, Seliger B. Distinct molecular mechanisms of altered HLA class II expression in malignant melanoma. Cancers (Basel). 2021 Aug 3;13(15):3907. doi: 10.3390/cancers13153907
Müller-Deile J, Sarau G, Kotb AM, Jaremenko C, Rolle-Kampczyk UE, Daniel C, Kalkhof S, Christiansen SH, Schiffer M. Novel diagnostic and therapeutic techniques reveal changed metabolic profiles in recurrent focal segmental glomerulosclerosis. Sci Rep. 2021 Feb 25;11(1):4577. doi: 10.1038/s41598-021-83883-w
Oliveira-Filho EF, Fischer C, Berneck BS, Carneiro IO, Kühne A, Almeida Campos A C, Ribas J R L, Netto EM, Franke CR, Ulbert S, Drexler JF. Ecologic determinants of West Nile virus seroprevalence among equids, Brazil. Emerg Infect Dis. 27 (2021), 9, Seite 2466-2470. doi: 10.3201/eid2709.204706
Peter AS, Roth E, Schulz SR, Fraedrich K, Steinmetz T, Damm D, Hauke M, Richel E, Mueller-Schmucker S, Habenicht K, Eberlein V, Issmail L, Uhlig N, Dolles S, Grüner E, Peterhoff D, Ciesek S, Hoffmann M, Pöhlmann S, McKay PF, Shattock RJ, Wölfel R, Socher E, Wagner R, Eichler J, Sticht H, Schuh W, Neipel F, Ensser A, Mielenz D, Tenbusch M, Winkler TH, Grunwald T, Überla K, Jäck H-M. A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model. Eur J Immunol. (2021), Aug 6. doi: 10.1002/eji.202149374
Ramsbeck D, Taudte N, Jänckel N, Strich S, Rahfeld J-U, Buchholz M. Tetrahydroimidazo[4,5-c]pyridine-based inhibitors of Porphyromonas gingivalis glutaminyl cyclase. Pharmaceuticals 14 (2021), 12, 1206. doi: 10.3390/ph14121206
Reiß F, Kiefer N, Noll M, Kalkhof S. Application, release, ecotoxicological assessment of biocide in building materials and its soil microbial response. Ecotoxicol Environ Saf. (2021), 224, 112707. doi: 10.1016/j.ecoenv.2021.112707
Reschke R, Gussek P, Boldt A, Sack U, Köhl U, Lordick F, Gora T, Kreuz M, Reiche K, Simon JC, Ziemer M, Kunz M. Distinct immune signatures indicative of treatment response and immune-related adverse events in melanoma patients under immune checkpoint inhibitor therapy. Int J Mol Sci. 22 (2021), 15, 8017. doi: 10.3390/ijms22158017
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Sack U, Fricke S. Can flow cytometry outperform genetic testing in eosinophilia patients? Cytometry A 99 (2021), 8 Seite 772-773. doi: 10.1002/cyto.a.24311
Saha S, Allelein S, Pandey R, Medina-Perez P, Osman E, Kuhlmeier D, Soleymani L. Two-step competitive hybridization assay: a method for analyzing cancer-related microRNA embedded in extracellular vesicles. Anal Chem. 93 (2021), 48, Seite 15913-15921. doi: 10.1021/acs.analchem.1c03165
Schaffert A, Krieg L, Weiner J, Schlichting R, Ueberham E, Karkossa I, Bauer M, Landgraf K, Junge K M, Wabitsch M, Lehmann J, Escher B I, Zenclussen A C, Körner A, Blüher M, Heiker J T, Bergen M, Schubert K. Alternatives for the worse: molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation. Environ Int. (2021), 156:106730. doi: 10.1016/j.envint.2021.106730
Schätzl T, Kaiser L, Deigner H-P. Facioscapulohumeral muscular dystrophy: genetics, gene activation and downstream signalling with regard to recent therapeutic approaches: an update. Orphanet J Rare Dis. 16 (2021), 1, 129. doi: 10.1186/s13023-021-01760-1
Schlegel K, Lidzba N, Ueberham E, Eisner P, Schweiggert-Weisz U. Fermentation of lupin protein hydrolysates - effects on their functional properties, sensory profile and the allergenic potential of the major lupin allergen lup an 1. Foods 10 (2021), 2, 281. doi: 10.3390/foods10020281
Schmidt M, Rohde F, Braumann U-D. Visualization and co-registration of correlative microscopy data with the ImageJ plug-in Correlia. Methods Cell Biol. (2021), 162, Seite 353-388. doi: 10.1016/bs.mcb.2020.10.001
Schmiedel D, Hezroni H, Hamburg A, Shulman Z. Brg1 supports B cell proliferation and germinal center formation through enhancer activation. Front Immunol. (2021) 12, 705848. doi: 10.3389/fimmu.2021.705848
Schnauß J, Kunschmann T, Grosser S, Zech T, Freitag J S, Prasevic D, Stange R, Röttger L S, Rönicke S, Smith D M, Bayerl T M, Käs J A. Cells in slow motion: apparent undercooling increases glassy behavior at physiological temperatures. Adv Mater. (2021), 33, 29, e2101840. doi: 10.1002/adma.202101840
Shibru B, Fey K, Fricke S, Blaudszun A-R, Fürst F, Weise M, Seiffert S, Weyh MK, Köhl U, Sack U, Boldt A. Detection of immune checkpoint receptors - a current challenge in clinical flow cytometry. Front Immunol. (2021), 12, 694055. doi: 10.3389/fimmu.2021.694055
Stauber T, Wolleb M, Duss A, Jaeger P K, Heggli I, Hussein A A, Blache U, Snedeker J G. Extrinsic macrophages protect while tendon progenitors degrade: insights from a tissue engineered model of tendon compartmental crosstalk. Adv Healthc Mater. (2021), 10, 20, e2100741. doi: 10.1002/adhm.202100741
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Tan K, Jäger C, Körschgen H, Geissler S, Schlenzig D, Buchholz M, Stöcker W, Ramsbeck D. Heteroaromatic inhibitors of the astacin proteinases meprin α, meprin β and ovastacin discovered by a scaffold-hopping approach. ChemMedChem. (2021), 16, 6, Seite 976-988. doi: 10.1002/cmdc.202000822
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Publikationen 2020

Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H. Data on medicinal plants used by herbalists for boosting immunity in people living with HIV/AIDS in Uganda. Data in Brief 29 (2020) Artikel-Nr.: 105097, 4 Seiten. dx.doi.org/10.1016/j.dib.2019.105097
Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H. Medicinal plants used by traditional medicine practitioners to boost the immune system in people living with HIV/AIDS in Uganda. European journal of integrative medicine 35 (2020) article 101011. dx.doi.org/10.1016/j.eujim.2019.101011
Ayobahan SU, Eilebrecht S, Baumann L, Teigeler M, Hollert H, Kalkhof S, Eilebrecht E, Schäfers C. Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Chemosphere 240 (2020), 124970. dx.doi.org/10.1016/j.chemosphere.2019.124970
Bauer BU, Runge M, Campe A, Henning KJ, Mertens-Scholz K, Boden K, Sobotta K, Frangoulidis D, Knittler MR, Matthiesen S, Berens C, Lührmann A, Fischer SF, Ulbert S, Makert GR, Ganter M. Coxiella burnetii: ein Übersichtsartikel mit Fokus auf das Infektionsgeschehen in deutschen Schaf- und Ziegenherden / a review focusing on infections in German sheep and goat flocks. Berliner und Münchener tierärztliche Wochenschrift 133 (2020) 3-4, Seite 184-200. dx.doi.org/10.2376/0005-9366-19030
Bedulina D, Drozdova P, Gurkov A, von Bergen M, Stadler PF, Luckenbach T, Timofeyev M, Kalkhof S. Proteomics reveals sex-specific heat shock response of Baikal amphipod Eulimnogammarus cyaneus. Science of The Total Environment (2020) Oct, 143008. dx.doi.org/10.1016/j.scitotenv.2020.143008
Berneck BS, Rockstroh A, Fertey J, Grunwald T, Ulbert S. A recombinant zika virus envelope protein with mutations in the conserved fusion loop leads to reduced antibody cross-reactivity upon vaccination. Vaccines 8 (2020) 4, Artikel-Nr.: 603, 10 Seiten. dx.doi.org/10.3390/vaccines8040603
Binder S, Zipfel I, Friedrich M, Riedel D, Ende S, Kämpf C, Wiedemann K, Buschmann T, Puppel SH, Reiche K, Stadler PF, Horn F. Master and servant: LINC00152 - a STAT3-induced long noncoding RNA regulates STAT3 in a positive feedback in human multiple myeloma. BMC medical genomics 13 (Februar 2020) Artikelnr.: 22, 13 Seiten. dx.doi.org/10.1186/s12920-020-0692-3
Bitar M, Boettcher M, Boldt A, Hauck F, Köhl U, Liebert UG, Magg T, Schulz MS, Sack U. Flow cytometric measurement of STAT5 phosphorylation in CMV stimulated T Cells. Cytometry A (2020), Dec 6. dx.doi.org/10.1002/cyto.a.24286
Bribiesca E, Braumann U-D, Carrillo-Bermejo A, Sossa-Azuela H. An approach to the computation of the Euler number by means of the vertex chain code. Computational and mathematical methods in medicine (2020),2020:5632159, dx.doi.org/10.1155/2020/5632159
Buniatian GH, Weiskirchen R, Weiss TS, Schwinghammer U, Fritz M, Seferyan T, Proksch B, Glaser M, Lourhmati A, Buadze M, Borkham-Kamphorst E, Gaunitz F, Gleiter CH, Lang T, Schaeffeler E, Tremmel R, Cynis H, Frey WH II, Gebhardt R, Friedmann SL, Mikulits W, Schwab M, Danielyan L. Antifibrotic effects of amyloid-beta and its loss in cirrhotic liver. Cells 9 (2020) 2, 22 Seiten. dx.doi.org/10.3390/cells9020452
Chauhan SKS, Koehl U, Kloess S. Harnessing NK Cell Checkpoint-Modulating Immunotherapies. Cancers 12 (2020), article number:1807. dx.doi.org/10.3390/cancers12071807
Cohnen J, Kornstädt L, Hahnefeld L, Ferreiros N, Pierre S, Koehl U, Deller T, Geisslinger G, Scholich K. Tumors Provoke Inflammation and Perineural Microlesions at Adjacent Peripheral Nerves. Cells 9 (2020), 2:320. dx.doi.org/10.3390/cells9020320
Crehan H, Liu B, Kleinschmidt M, Rahfeld J-U, Le KX, Caldarone BJ, Frost JL, Hettmann T, Hutter-Paier B, O'Nuallain B, Park M-A, DiCarli MF, Lues I, Schilling S, Lemere CA. Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's like mice. Alzheimer's research & therapy 12 (2020) Artikelnr.: 12 (2020), 19 Seiten. dx.doi.org/10.1186/s13195-019-0579-8
Derrick T, Sandetskaya N, Pickering H, Kölsch A, Ramadhani A, Mafuru E, Massae P, Malisa A, Mtuy T, Burton MJ, Holland MJ, Kuhlmeier D. DjinniChip: evaluation of a novel molecular rapid diagnostic device for the detection of Chlamydia trachomatis in trachoma-endemic areas. Parasites & vectors 13 (2020) Artikel-Nr.: 533, 10 Seiten. dx.doi.org/10.1186/s13071-020-04414-6
Dudaie M, Nissim N, Barnea I, Gerling T, Duschl C, Kirschbaum M, Shaked NT. Label-free discrimination and selection of cancer cells from blood during flow using holography-induced dielectrophoresis. J. Biophotonics. 2020;13:e202000151. dx.doi.org/10.1002/jbio.202000151
Fertey J, Bayer L, Kähl S, Haji RM, Burger-Kentischer A, Thoma M, Standfest B, Schönfelder J, Portillo Casado J, Rögner FH, Baums CG, Grunwald T, Ulbert S. Low-Energy Electron Irradiation Efficiently Inactivates the Gram-Negative Pathogen Rodentibacter pneumotropicus-A New Method for the Generation of Bacterial Vaccines with Increased Efficacy. Vaccines (Basel). 2020 Mar 2;8(1):113. dx.doi.org/10.3390/vaccines8010113
Fertey J, Thoma M, Beckmann J, Finkensieper J, Reißhauer S, Berneck BS, Issmail L, Schönfelder J, Casado JP, Poremba A, Rögner F-H, Standfest B, Makert GR, Walcher L, Kistenmacher A-K, Fricke S, Grunwald T, Ulbert S, Bayer L. Automated application of low energy electron irradiation enables inactivation of pathogen- and cell-containing liquids in biomedical research and production facilities. Scientific reports 10 (2020) 1, Artikel-Nr.: 12786, 14 Seiten. dx.doi.org/10.1038/s41598-020-69347-7
Friedrich M, Wiedemann K, Reiche K, Puppel SH, Pfeifer G, Zipfel I, Binder S, Koehl U, Mueller GA, Engeland K, Aigner A, Füssel, S, Fröhner M, Peitzsch C, Dubrovska A, Rade M, Christ S, Schreiber S, Hackermüller J, Lehmann J, Toma MI, Muders MH, Sommer U, Baretton GB, Wirth MP, Horn F. The role of lncRNAs TAPIR-1 and-2 as diagnostic markers and potential therapeutic targets in prostate cancer. Cancers 12 (Mai 2020) 5, 1122, 27 Seiten. dx.doi.org/10.3390/cancers12051122
Gehre C, Flechner M, Kammerer S, Küpper JH, Coleman CD, Püschel GP, Uhlig K, Duschl C. Real time monitoring of oxygen uptake of hepatocytes in a microreactor using optical microsensors. Scientific Reports 10 (2020), 1:13700. dx.doi.org/10.1038/s41598-020-70785-6
Gnoth K, Piechotta A, Kleinschmidt M, Konrath S, Schenk M, Taudte N, Ramsbeck D, Nykiel V, Geißler S, Eichentopf R, Barendrecht S, Hartlage-Rübsamen M, Demuth H-U, Roßner S, Cynis H, Rahfeld J-U, Schilling S. Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology. Alzheimer's research & therapy 12 (2020) Artikel-Nr.: 149, 20 Seiten. dx.doi.org/10.1186/s13195-020-00719-x
Gröger V, Wieland L, Naumann M, Meinecke A-C, Meinhardt B, Roßner S, Ihling C, Emmer A, Staege MS, Cynis H. Formation of herv-k and herv-fc1 envelope family members is suppressed on transcriptional and translational level. International journal of molecular sciences 21 (2020) 21, Artikel-Nr.: 7855, 23 Seiten. dx.doi.org/10.3390/ijms21217855
Hahn MB, Smales GJ, Seitz H, Solomun T, Sturm H. Interaction with DNA: Influence on Ultraviolet Radiation Damage. Phys Chem Chem Phys 2020; Vol. 22(13): 6984-6992. dx.doi.org/10.1039/d0cp00092b
Heilig CE, Badoglio M, Labopin M, Fröhling S, Secondino S, Heinz J, Nicolas-Virelizier E, Blaise D, Korenbaum C, Santoro A, Verbeek M, Krüger W, Siena S, Passweg JR, Di Nicola M, Rifón J, Dreger P, Koehl U, Chabannon C, Pedrazzoli P. Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: an analysis from the European Society for Blood and Marrow Transplantation. ESMO Open. 2020 Oct;5(5):e000860. dx.doi.org/10.1136/esmoopen-2020-000860
Hettmann T, Gillies SD, Kleinschmidt M, Piechotta A, Makioka K, Lemere CA, Schilling S, Rahfeld J-U, Lues I. Development of the clinical candidate PBD-C06, a humanized pGlu3-Aβ-specifc antibody against Alzheimer's disease with reduced complement activation. Scientific reports 10 (2020) Artikel-Nr.: 3294, 13 Seiten. dx.doi.org/10.1038/s41598-020-60319-5
Hsu MJ, Karkossa I, Schäfer I, Christ M, Kühne H, Schubert K, Rolle-Kampczyk UE, Kalkhof S, Nickel S, Seibel P, von Bergen M, Christ B. Mitochondrial Transfer by Human Mesenchymal Stromal Cells Ameliorates Hepatocyte Lipid Load in a Mouse Model of NASH. Biomedicines 8 (2020), 9, :350. dx.doi.org/10.3390/biomedicines8090350
Jansig E, Geissler S, Rieckmann V, Kuenemund A, Hietel B, Schenk M, Wussow S, Kreideweiss P, Panzner S, Reinsch C, Cynis H. Viromers as carriers for mRNA-mediated expression of therapeutic molecules under inflammatory conditions. Scientific Reports 10 (2020), article number: 15090. dx.doi.org/10.1038/s41598-020-72004-8
Jnana A, Muthuraman V, Varghese VK, Chakrabarty S, Murali TS, Ramachandra L, Shenoy KR, Rodrigues GS, Prasad SS, Dendukuri D, Morschhauser A, Nestler J, Peter H, Bier FF, Satyamoorthy K. Microbial Community Distribution and Core Microbiome in Successive Wound Grades of Individuals with Diabetic Foot Ulcers. Appl Environ Microbiol. 2020 Mar 2;86(6):e02608-19. dx.doi.org/10.1128/AEM.02608-19
Kähl S, Volke D, Fornefett J, Fingas F, Klose K, Benga L, Grunwald T, Ulrich R, Hoffmann R, Baums CG. Identification of a large repetitive RTX immunogen in a highly virulent Rodentibacter heylii strain. Microbes and Infection 23 (2020), S1286-4579(20)30185-4. dx.doi.org/10.1016/j.micinf.2020.10.007
Kalkhof S, Krieg L, Büttner P, Wabitsch M, Küntzel C, Friebe D, Landgraf K, Hanschkow M, Schubert K, Kiess W, Krohn K, Blüher M, von Bergen M, Körner A. In Depth Quantitative Proteomic and Transcriptomic Characterization of Human Adipocyte Differentiation Using the SGBS Cell Line. Proteomics (2020), May, e1900405. dx.doi.org/10.1002/pmic.201900405
Keller M, Meir AY, Bernhart SH, Gepner Y, Shelef I, Schwarzfuß D, Tsaban G, Zelicha H, Hopp L, Müller L, Rohde K, Böttcher Y, Stadler PF, Stumvoll M, Blüher M, Kovacs P, Shai I. DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial. Genome medicine 12 (2020) 1, Artikel-Nr.: 97, 18 Seiten. dx.doi.org/10.1186/s13073-020-00794-7
Kirchberg M, Eick S, Buchholz M, Rosche F, Kiesow A, Sarembe S, Mäder K. Controlled release minocycline-lipid-complex extrudates for the therapy of periodontitis with enhanced flexibility. International journal of pharmaceutics 568 (2020) Artikel-Nr.: 119578. dx.doi.org/10.1016/j.ijpharm.2020.119578
Klöß S, Dehmel S, Braun A, Parnham MJ, Köhl U, Schiffmann S. From Cancer to Immune-Mediated Diseases and Tolerance Induction: Lessons Learned From Immune Oncology and Classical Anti-cancer Treatment. Frontiers of Immunology (2020), 11:1423. dx.doi.org/10.3389/fimmu.2020.01423. eCollection 2020
Köppen J, Schulze A, Machner L, Wermann M, Eichentopf R, Guthardt M, Hähnel A, Klehm J, Kriegeskorte M-C, Hartlage-Rübsamen M, Morawski M, Hörsten S von, Demuth H-U, Roßner S, Schilling S. Amyloid-beta peptides trigger aggregation of alpha-synuclein in vitro. Molecules Volume 25 (2020) Issue 3, 18 Seiten. dx.doi.org/10.3390/molecules25030580
Körner S, Makert G, Mertens-Scholz K, Henning K, Pfeffer M, Starke A, Nijhof AM, Ulbert, S. Uptake and fecal excretion of coxiella burnetii by Ixodes ricinus and dermacentor marginatus ticks. Parasites & Vectors 13 (2020), 11 Seiten. dx.doi.org/10.1186/s13071-020-3956-z
Körschgen H, Jäger C, Tan K, Buchholz M, Stöcker W, Ramsbeck D. A Primary Evaluation of Potential Small-Molecule Inhibitors of the Astacin Metalloproteinase Ovastacin, a Novel Drug Target in Female Infertility Treatment. ChemMedChem 15 (2020), 16, 1499-1504. dx.doi.org/10.1002/cmdc.202000397
Kreuz M, Otto DJ, Fuessel S, Blumert C, Bertram C, Bartsch S, Loeffler D, Puppel SH, Rade M, Buschmann T, Christ S, Erdmann K, Friedrich M, Froehner M, Muders MH, Schreiber S, Specht M, Toma MI, Benigni F, Freschi M, Gandaglia G, Briganti A, Baretton GB, Loeffler M, Hackermüller J, Reiche K, Wirth M, Horn F. ProstaTrend-A Multivariable Prognostic RNA Expression Score for Aggressive Prostate Cancer. European Urology 78 (2020), 3, Seite 452-459. dx.doi.org/10.1016/j.eururo.2020.06.001
Kupski O, Funk L-M, Sautner V, Seifert F, Worbs B, Ramsbeck D, Meyer F, Diederichsen U, Buchholz M, Schilling S, Demuth H-U, Tittmann K. Hydrazides are potent transition-state analogues for glutaminyl cyclase implicated in the pathogenesis of Alzheimer's disease. Biochemistry 59 (2020) 28, Seite 2585-2591. dx.doi.org/10.1021/acs.biochem.0c00337
Kutovyi Y, Hlukhova H, Boichuk N, Menger M, Offenhäusser A, Vitusevich S. Amyloid-beta peptide detection via aptamer-functionalized nanowire sensors exploiting single-trap phenomena. Biosens Bioelectron. 2020;154:112053. dx.doi.org/10.1016/j.bios.2020.112053
Kutovyi Y, Li J, Zadorozhnyi I, Hlukhova H, Boichuk N, Yehorov D, Menger M, Vitusevich S. Highly Sensitive and Fast Detection of C-Reactive Protein and Troponin Biomarkers Using Liquidgated Single Silicon Nanowire Biosensors. MRS Advances 2020, 5(16), 835-846. dx.doi.org/10.1557/adv.2020.60
Kwesiga G, Kelling A, Kersting S, Sperlich E, von Nickisch-Rosenegk M, Schmidt B. Total Syntheses of Prenylated Isoflavones from Erythrina sacleuxii and Their Antibacterial Activity: 5-Deoxy-3'-prenylbiochanin A and Erysubin F. Journal of Natural Products 83 (2020), 11, Seite 3445-3453. dx.doi.org/10.1021/acs.jnatprod.0c00932
Laur N, Kinscherf R, Pomytkin K, Kaiser L, Knes O, Deigner HP. ICP-MS trace element analysis in serum and whole blood. PLoS ONE 15 (2020) 5, e0233357, 14 Seiten. dx.doi.org/10.1371/journal.pone.0233357
Leya T. The CCCryo Culture Collection of Cryophilic Algae as a valuable bioresource for algal biodiversity and for novel, industrially marketable metabolites. Applied Phycology 1 (2020), S1, S. 1-22. dx.doi.org/10.1080/26388081.2020.1753572
Marquardt P, Seide R, Vissiennon C, Schubert A, Birkemeyer C, Ahyi V, Fester K. Phytochemical characterization and in vitro anti-inflammatory, antioxidant and antimicrobial activity of Combretum Collinum Fresen leaves extracts from Benin. Molecules 25 (2020) 2, 18 Seiten. dx.doi.org/10.3390/molecules25020288
Marquardt P, Vissiennon C, Schubert A, Birkemeyer C, Ahyi V, Fester K. Phytochemical analysis, in vitro anti-inflammatory and antimicrobial activity of Pilistigma thonningii leaf extracts from Benin. Planta medica 86 (2020), 17, Seite 1269-1277. dx.doi.org/10.1055/a-1229-4565
Mohebali N, Ekat K, Kreikemeyer B, Breitrück A. Barrier Protection and Recovery Effects of Gut Commensal Bacteria on Differentiated Intestinal Epithelial Cells In Vitro. Nutrients (2020), 8, 2251. dx.doi.org/10.3390/nu12082251
Monasor LS, Müller SA, Colombo AV, Tanrioever G, König J, Roth S, Liesz A, Berghofer A, Piechotta A, Prestel M, Saito T, Saido TC, Herms J,Willem M, Haass C, Lichtenthaler SF, Tahirovic S. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. eLife 9 (2020) Artikel-Nr.: 54083, 33 Seiten. dx.doi.org/10.7554/eLife.54083
Moreira-Soto A, Souza Sampaio G de, Pedroso C, Postigo-Hidalgo I, Berneck BS, Ulbert S, Brites CR, Netto EM, Drexler JF. Rapid decline of Zika virus NS1 antigen-specific antibody responses, northeastern Brazil. Virus genes (2020) short report, 6 Seiten. dx.doi.org/10.1007/s11262-020-01772-2
Müller S, Bexte T, Gebel V, Kalensee F, Stolzenberg E, Hartmann J, Koehl U, Schambach A, Wels WS, Modlich U, Ullrich E. High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia. Frontiers in Immunology 10 (2020), 3123. dx.doi.org/10.3389/fimmu.2019.03123. eCollection 2019.
Nasr W, Fabian C, Arnold K, Koehl U, Sack U, Weiss R, Cross M, Hauschildt S. Nicotinamide inhibits self-renewal and induces granulocyte differentiation of multipotent progenitor cells. Stem cell reviews and reports 16 (2020), Seite 1335-1342. dx.doi.org/10.1007/s12015-020-10019-4
Nitsche A, Arnold C, Ueberham U, Reiche K, Fallmann J, Hackermüller J, Stadler PF, Arendt T. Alzheimer-related genes show accelerated evolution. Molecular psychiatry (2020) 7 Seiten. dx.doi.org/10.1038/s41380-020-0680-1
Obendorf J, Fabian C, Thome UH, Laube M. Paracrine stimulation of perinatal lung functional and structural maturation by mesenchymal stem cells. Stem Cell Res Ther. 2020 Dec 9;11(1):525. dx.doi.org/10.1186/s13287-020-02028-4
Omar MI, Roobol MJ, Ribal MJ, Abbott T, Agapow PM, Araujo S, Asiimwe A, Auffray C, Balaur I, Beyer K, Bernini C, Bjartell A, Briganti A, Butler-Ransohoff JE, Campi R, Cavelaars M, De Meulder B, Devecseri Z, Voss MD, Dimitropoulos K, Evans-Axelsson S, Franks B, Fullwood L, Horgan D, Smith EJ, Kiran A, Kivinummi K, Lambrecht M, Lancet D, Lindgren P, MacLennan S, MacLennan S, Nogueira MM, Moen F, Moinat M, Papineni K, Reich C, Reiche K, Rogiers S, Sartini C, van Bochove K, van Diggelen F, Van Hemelrijck M, Van Poppel H, Zong J, N'Dow J; PIONEER Consortium. Introducing PIONEER: a project to harness big data in prostate cancer research. Nature Reviews Urology 17 (2020), 6, Seite 351-362. dx.doi.org/10.1038/s41585-020-0324-x
Ramírez Caballero L, Kny C, Treudler R, Simon JC, Kern K, Jappe U, Szardenings M. Identification of seasonal variations of antibodies against PR-10-specific epitopes can be improved using peptide-phage display. International archives of allergy and immunology (2020) 7 Seiten. dx.doi.org/10.1159/000509995
Ramm F, Dondapati SK, Thoring L, Zemella A, Wüstenhagen DA, Frentzel H, Stech M, Kubick S. Mammalian cell-free protein expression promotes the functional characterization of the tripartite non-hemolytic enterotoxin from Bacillus cereus. Sci Rep 10, 2887 (2020). dx.doi.org/10.1038/s41598-020-59634-8
Rohde F, Braumann U-D, Schmidt M. Correlia: an ImageJ plug-in to co-register and visualise multimodal correlative micrographs. Journal of Microscopy (2020), 280(1):3–11, dx.doi.org/10.1111/jmi.12928
Ros S, Freitag JS, Smith DM, Stöver HDH. Charge-shifting polycations based on N, N-(dimethylamino)ethyl acrylate for improving cytocompatibility during DNA delivery. ACS omega 5 (April 2020) 16, Seite 9114-9122. dx.doi.org/10.1021/acsomega.9b03734
Saidu NEB, Bonini C, Dickinson A, Grce M, Inngjerdingen M, Koehl U, Toubert A, Zeiser R, Galimberti S. New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions. Frontiers in Immunology 11 (2020), 578314. dx.doi.org/10.3389/fimmu.2020.578314. eCollection 2020
Schmid J-L, Kirchberg M, Sarembe S, Kiesow A, Sculean A, Mäder K, Buchholz M, Eick S. In vitro evaluation of antimicrobial activity of minocycline formulations for topical application in periodontal therapy. Pharmaceutics 12 (2020) 4, 352, 14 Seiten. dx.doi.org/10.3390/pharmaceutics12040352
Schnauß J, Schmidt BUS, Brazel CB, Senol D, Losert W, Anderegg U, Käs JA. Influence of hyaluronic acid binding on the actin cortex measured by optical forces. Journal of biophotonics (2020) Artikel-Nr.: e201960215, 9 Seiten. dx.doi.org/10.1002/jbio.201960215
Semwal DK, Chauhan A, Semwal RB, Sircar D, Roy P, Lehmann J. Natural molecules having anti-SARS-CoV activity – cannot they be effective against SARS-CoV-2?. Current science 119 (2020) 5, Seite 757-770. dx.doi.org/10.18520/cs/v119/i5/757-770
Shehata AA, Basiouni S, Ali A, Fawzy M, Hafez HM, Ulbert S, Vahlenkamp TW. Immunization of turkeys with a DNA vaccine expressing the haemagglutinin gene of low pathogenic avian influenza virus subtype H9N2. Journal of virological methods 284 (2020) Artikel-Nr.: 113938. dx.doi.org/10.1016/j.jviromet.2020.113938
Siccardi S, Adamatzky A, Tuszyński J, Huber F, Schnauß J. Actin networks voltage circuits. Physical Review E 101 (2020), 5, 052314. dx.doi.org/10.1103/PhysRevE.101.052314
Sinjari S, Freitag JS, Herold C, Otto O, Smith DM, Stöver HDH. Tunable polymer microgel particles and their study using microscopy and realtime deformability cytometry. Journal of Polymer Science (2020), Seite 2317-2326. dx.doi.org/10.1002/pol.20200274
Sun J, Tárnok A, Su X. Deep learning-based single-cell optical image studies. Cytometry Part A 97A (2020) 3, Seite 226-240. dx.doi.org/10.1002/cyto.a.23973
Sun J, Wang L, Liu Q, Tárnok A, Su X. Deep learning-based light scattering microfluidic cytometry for label-free acute lymphocytic leukemia classification. Biomedical optics express 11 (2020) 11, Seite 6674-6686. dx.doi.org/10.1364/BOE.405557
Tan K, Jäger C, Körschgen H, Geissler S, Schlenzig D, Buchholz M, Stöcker W, Ramsbeck D. Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold-Hopping Approach. ChemMedChem 2020 Dec 23. dx.doi.org/10.1002/cmdc.202000822
Treudler R, Delaroque N, Puder M, Simon JC, Szardenings M. Dupilumab-induced serum sickness-like reaction: an unusual adverse effect in a patient with atopic eczema. Journal of the European Academy of Dermatology and Venereology (2020) 3 Seiten. dx.doi.org/10.1111/jdv.16782
Uhlmann RE, Rother C, Rasmussen J, Schelle J, Bergmann C, Ullrich Gavilanes EM, Fritschi SK, Buehler A, Baumann F, Skodras A, Al Shaana R, Beschorner N, Ye L, Kaeser SA, Obermüller U, Christensen S, Kartberg F, Stavenhagen JB, Rahfeld JU, Cynis H, Qian F, Weinreb PH, Bussiere T, Walker LC, Staufenbiel M, Jucker M. Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life. Nature Neuroscience 23 (2020), Seite 1580–1588. dx.doi.org/10.1038/s41593-020-00737-w
Ulrich H, Pillat MM, Tárnok A. Dengue fever, COVID-19 (SARS-CoV-2), and Antibody-Dependent Enhancement (ADE): a perspective. Cytometry Part A 97 (2020) 6 Seiten. dx.doi.org/10.1002/cyto.a.24047
Wagner M, Reinke S, Hänsel R, Klapper W, Braumann U-D. An image dataset related to automated macrophage detection in immunostained lymphoma tissue samples. GigaScience 9 (2020), 9(3):giaa016, dx.doi.org/10.1093/gigascience/giaa016
Walcher L, Hilger N, Wege AK, Lange F, Tretbar S, Blaudszun A-R, Fricke S. Humanized mouse model: hematopoietic stemcell transplantation and tracking using short tandem repeat technology. Immunity, inflammation and disease (2020) Seite 1-8. dx.doi.org/10.1002/iid3.317
Warnecke A, Harre J, Staecker H, Prenzler N, Strunk D, Couillard-Despres S, Romanelli P, Hollerweger J, Lassacher T, Auer D, Pachler K, Wietzorrek G, Köhl U, Lenarz T, Schallmoser K, Laner-Plamberger S, Falk CS, Rohde E, Gimona M. Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo. Clinical and Translational Medicine 10 (2020), 8article number:e262. dx.doi.org/10.1002/ctm2.262
Winkel A, Jaimes Y, Melzer C, Dillschneider P, Hartwig H, Stiesch M, von der Ohe J, Strauss S, Vogt PM, Hamm A, Burmeister L, Roger Y, Elger K, Floerkemeier T, Weissinger EM, Pogozhykh O, Müller T, Selich A, Rothe M, Petri S, Köhl U, Hass R, Hoffmann A. Cell culture media notably influence properties of human mesenchymal stroma/stem-like cells from different tissues. Cytotherapy (2020), S1465-3249(20)30792-1. dx.doi.org/10.1016/j.jcyt.2020.07.005.32855067
Wüstenhagen DA, Lukas P, Müller C, Aubele SA, Hildebrandt JP, Kubick S. Cell-free synthesis of the hirudin variant 1 of the blood-sucking leech Hirudo medicinalis. Sci Rep, 2020 Nov 13;10(1):19818. dx.doi.org/10.1038/s41598-020-76715-w
Xin Y, Kielar C, Zhu S, Sikeler C, Xu X, Möser C, Grundmeier G, Liedl T, Heuer-Jungemann A, Smith DM, Keller A. Cryopreservation of DNA origami nanostructures. Small 16 (2020) 13, 7 Seiten. dx.doi.org/10.1002/smll.201905959
Yakoub-Agha I, Chabannon C, Bader P, Basak GW, Bonig H, Ciceri F, Corbacioglu S, Duarte RF, Einsele H, Hudecek M, Kersten MJ, Köhl U, Kuball J, Mielke S, Mohty M, Murray J, Nagler A, Robinson S, Saccardi R, Sanchez-Guijo F, Snowden JA, Srour M, Styczynski J, Urbano-Ispizua A, Hayden PJ, Kröger N. Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE). Haematologica. 105 (2020), 2:297-316. dx.doi.org/10.3324/haematol.2019.229781
Zhupanyn P, Ewe A, Büch T, Malek A, Rademacher P, Müller C, Reinert A, Jaimes Y, Aigner A. Extracellular vesicle (ECV)-modified polyethylenimine (PEI) complexes for enhanced siRNA delivery in vitro and in vivo. Journal of controlled release 319 (2020) Seite 63-76. dx.doi.org/10.1016/j.jconrel.2019.12.032

Publikationen 2019

Adamatzky A, Huber F, Schnauß J. Computing on actin bundles network. Scientific Reports 9 (2019), 1, 15887, 10 Seiten. dx.doi.org/10.1038/s41598-019-51354-y
Adamatzky A, Schnauß J, Huber F. Actin droplet machine. Royal Society Open Science 6 (2019), 12, 191135, 16 Seiten. dx.doi.org/10.1098/rsos.191135
Aleksandrova K, Leise J, Priesner C, Melk A, Kubaink F, Abken H, Hombach A, Aktas M, Essl M, Bürger I, Kaiser A, Rauser G, Jurk M, Goudeva L, Glienke W, Arseniev L, Esser R, Köhl U. Functionality and cell senescence of CD4/CD8-selected CD20 CAR T cells manufactured using the automated CliniMACS Prodigy® platform. Transfusion medicine and hemotherapy 45 (2019), 1, Seite 47-54. dx.doi.org/10.1159/000495772
Al-Essa MK, Melzer S, Tárnok A. Two-color analysis of leukocytes labeled by modified RBCs and their fragments. Cytometry Part A 95 (2019), 3, Seite 339-346, dx.doi.org/10.1002/cyto.a.23682
Anywar G, Kakudidi E, Byamukama R, Mukonzo J, Schubert A, Oryem-Origa H. Indigenous traditional knowledge of medicinal plants used by herbalists in treating opportunistic infections among people living with HIV/AIDS in Uganda. Journal of Ethnopharmacology 246 (2020), article 112205 13 Seiten, dx.doi.org/10.1016/j.jep.2019.112205
Aswal S, Kumar A, Semwal RB, Chauhan A, Kumar A, Lehmann J, Semwal DK. Drimia indica: a plant used in traditional medicine and its potential for clinical uses. Medicina 55 (2019), 6, 16 Seiten, dx.doi.org/10.3390/
medicina55060255
Ayobahan SU, Eilebrecht E, Kotthoff M, Baumann L, Eilebrecht S, Teigeler M, Hollert H, Kalkhof S, Schäfers C. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. Scientific reports 9 (2019), 6599, 12 Seiten. dx.doi.org/10.1038/s41598-019-43089-7
Ayobahan SU, Eilebrecht S, Baumann L, Teigeler M, Hollert H, Kalkhof S, Eilebrecht E, Schäfers C. Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Chemosphere 240 (2020), 124970, 12 Seiten.
dx.doi.org/10.1016/j.chemosphere.2019.124970
Barth M, Gröger V, Cynis H, Staege MS. Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells. Molecular biology reports 46 (2019)2, Seite 1885-1893, dx.doi.org/10.1007/s11033-019-04640-x
Behm LVJ, Gerike S, Grauel MK, Uhlig K, Pfisterer F, Baumann W, Bier FF, Duschl C, Kirschbaum M. Micropatterned thermoresponsive cell culture substrates for dynamically controlling neurite outgrowth and neuronal connectivity in vitro. ACS Applied Bio Mater 7 (2019), 2, 2853-2861. dx.doi.org/10.1021/acsabm.9b00246
Belkum A, Bachmann TT, Lüdke G et al. Developmental roadmap for antimicrobial susceptibility testing systems. Nature Reviews Microbiology 17 (2019), S. 51-62. dx.doi.org/10.1038/s41579-018-0098-9
Bender P, Egger A, Westermann M, Taudte N, Sculean A, Potempa J, Möller B, Buchholz M, Eick S. Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis – a pilot study. Archives of oral biology 97 (2019), January, Seite 223-230, dx.doi.org/10.1016/j.archoralbio.2018.10.022
Bengtsson E, Tárnok A. Special section on image cytometry. Cytometry Part A 95 (2019), 4, Seite 363-365, dx.doi.org/10.1002/cyto.a.23762
Binner C, Wagner J, Schmalz G, Eisner M, Rast J, Kottmann T, Haak R, Oberbach A, Borger MA, Garbade J, Ziebolz D. Insufficient oral behaviour and the high need for periodontal treatment in patients with heart insufficiency and after heart transplantation: a need for special care programs? Journal of Clinical Medicine 8 (2019), 10, Articel 1668, 10 Seiten. dx.doi.org/10.3390/jcm8101668
Bitar M, Boldt A, Freitag MT, Gruhn B, Köhl U, Sack U. Evaluating STAT5 phosphorylation as a mean to assess T cell proliferation. Frontiers in immunology 10 (2019), article 722, 11 Seiten. dx.doi.org/10.3389/fimmu.2019.00722
Blaess M, Deigner HP. Derailed ceramide metabolism in atopic dermatitis (AD): a causal starting point for a personalized (basic) therapy. International journal of molecular sciences 20 (2019), 16, 15 Seiten, dx.doi.org/10.3390/ijms20163967
Bocker HT, Heinrich T, Liebmann L, Hennings JC, Seemann E, Gerth M, Jakovčevski I, Preobraschenski J, Kessels MM, Westermann M, Isbrandt D, Jahn R, Qualmann B, Hübner CA. The Na+/H+ exchanger Nhe1 modulates network excitability via GABA release. Cerebral cortex 13 (2019), 29, Seite 4263-4276, dx.doi.org/10.1093/cercor/bhy308
Bozza FA, Moreira-Soto A, Rockstroh A, Fischer C, Nascimento AD, Calheiros AS, Drosten C, Bozza PT, Souza TML, Ulbert S, Drexler JF. Differential shedding and antibody kinetics of Zika and Chikungunya Viruses, Brazil. Emerging Infectious Diseases 25(2019), 2, Seiten 311-315. dx.doi.org/10.3201/eid2502.180166
Bremm M, Pfeffermann LM, Cappel C, Katzki V1, Erben S, Betz S, Quaiser A, Merker M, Bonig H, Schmidt M, Klingebiel T, Bader P, Huenecke S, Rettinger E. Improving clinical manufacturing of IL-15 activated cytokine-induced killer (CIK) cells. Frontiers in immunology 10 (2019), Artikel 1218, 12 Seiten. dx.doi.org/10.3389/fimmu.2019.01218
Bursch F, Rath KJ, Sarikidi A, Böselt S, Kefalakes E, Osmanovic A, Thau-Habermann N, Klöß S, Köhl U, Petri S. Analysis of the therapeutic potential of different administration routes and frequencies of human mesenchymal stromal cells in the SOD1G93A mouse model of amyotrophic lateral sclerosis. J Tissue Eng Regen Med. 2019 Apr;13(4):649-663. dx.doi.org/10.1002/term.2846. Epub 2019 Mar 20.
Comoli P, Chabannon C, Koehl U, Lanza F, Urbano-Ispizua A, Hudecek M, Ruggeri A, Secondino S, Bonini C, Pedrazzoli P. Development of adaptive immune effector therapies in solid tumors. Ann Oncol. 2019 Nov 1;30(11):1740-1750. dx.doi.org/10.1093/annonc/mdz285
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology 49 (2019), 10, Seiten 1457-1973. dx.doi.org/10.1002/eji.201970107
Costa-Marques L, Katrin K, Pardon M, Leovsky C, Swarbrick S, Fabian C, Stolzing A. Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model. Translational Neurodegeneration 8 (2019), 33, 11 Seiten. dx.doi.org/10.1186/s40035-019-0173-9
Czechowska K, Lannigan J, Wang L, Arcidiacono J, Ashhurst TM, Barnard RM, Bauer S, Bispo C, Bonilla DL, Brinkman RR, Cabanski M, Chang HD, Chakrabarti L, Chojnowski G, Cotleur B, Degheidy H, Dela Cruz GV, Eck S, Elliott J, Errington R, Filby A, Gagnon D, Gardner R, Green C, Gregory M, Groves CJ, Hall C, Hammes F, Hedrick M, Hoffman R, Icha J, Ivaska J, Jenner DC, Jones D, Kerckhof FM, Kukat C, Lanham D, Leavesley S, Lee M, Lin-Gibson S, Litwin V, Liu Y, Molloy J, Moore JS, Müller S, Nedbal J, Niesner R, Nitta N, Ohlsson-Wilhelm B, Paul NE, Perfetto S, Portat Z, Props R, Radtke S, Rayanki R, Rieger A, Rogers S, Rubbens P, Salomon R, Schiemann M, Sharpe J, Sonder SU, Stewart JJ, Sun Y, Ulrich H, Van Isterdael G, Vitaliti A, van Vreden C, Weber M, Zimmermann J, Vacca G, Wallace P, Tárnok A. Cyt-Geist: current and future challenges in Cytometry: reports of the CYTO 2018 conference workshops. Cytometry Part A 95 (2019), 6, Seite 598-644, dx.doi.org/10.1002/cyto.a.23777
de Vera J-P, Alawi M, Backhaus T, Baqué M, Billi D, Böttger U, Berger T, Cockell C, Demets R, Noetzel R d l T, Edwards H, Elsaesser A, Fagliarone C, Fiedler A, Foing B, Foucher F, Fritz J, Hanke F, Herzog T, Horneck G, Hübers H-W, Huwe B, Joshi J, Kozyrovska N, Kruchten M, Lasch P, Lee N, Leya T, Lorek A, Moritz S, Möller R, Olsson-Francis K, Onofri S, Ott S, Pacelli C, Podolich O, Martínez-Frías J, Rabbow E, Reitz G, Rettberg P, Reva O, Rothschild L, Sancho L G, Schulze-Makuch D, Selbmann L, Serrano P, Szewzyk U, Verseux C, Wagner D, Westall F, Wolter D, Zucconi L. Limits of life and the habitability of Mars: The ESA space experiment BIOMEX on the ISS. Astrobiology 19 (2019), 2, Seiten 145-157. dx.doi.org/10.1089/ast.2018.1897
Dluczek S, Tretbar US, Fricke S, Koehl U. CAR-T-Zellen: Update 2019. Transfusionsmedizin 9 (2019), 3, Seiten 187-200, dx.doi.org/10.1055/a-0833-2631
Dondapati SK, Lübberding H, Zemella A, Thoring L, Wüstenhagen DA, Kubick S. Functional reconstitution of membrane proteins derived from Eukaryotic Cell-Free Systems. Frontiers in Pharmacology (2019), 9 Seiten. dx.doi.org/10.3389/fphar
Dondapati SK, Pietruschka G, Thoring L, Wüstenhagen DA, Kubick S. Cell-free synthesis of human toll-like receptor 9 (TLR9): Optimization of synthesis conditions and functional analysis. PLoS One 14 (2019), 4, e0215897, 16 Seiten. dx.doi.org/10.1371/journal.pone.0215897
Fayad L, Oberbach A, Schweitzer M, Askin F, Voltaggio L, Larman T, Enderle M, Hahn H, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization (GMD): translation to a novel endoscopic metabolic therapy. Endoscopy International Open (2019), 07, 6 Seiten. dx.doi.org/10.1055/a-0957-3067
Fayad L, Schweitzer M, Raad M, Simsek C, Oleas R, Dunlap MK, Shah T, Doshi J, El Asmar M, Oberbach A, Singh VK, Steele K, Magnussen T, Kalloo AN, Khashab MA, Kumbhari V. A real-world, insurance-based algorithm using the two-fold running suture technique for transoral outlet reduction for weight regain and dumping syndrome after Roux-En-Y gastric bypass. Obesity Surgery 29 (2019), Seiten 2225-2232. dx.doi.org/10.1007/s11695-019-03828-1
Fayad L, Simsek C, Oleas R, Ichkhanian Y, Fayad GE, Ngamreungphong S, Schweitzer M, Oberbach A, Kalloo AN, Khashab MA, Kumbhari V. Safety and efficacy of endoscopically secured fully covered self-expandable metallic stents (FCSEMS) for post-bariatric complex Stenosis. Obesity Surgery 29 (2019), Seiten 3484-3492. dx.doi.org/10.1007/s11695-019-04021-0
Frimmel S, Hinz M, Schipper J, Bogdanow S, Mitzner S, Koball S. Cytokine adsorption is a promising tool in the therapy of hemophagocytic lymphohistiocytosis. International Journal of Artificial Organs 42 (2019), 11,
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Gialluisi A, Andlauer TFM, Mirza-Schreiber N, Moll K, Becker J, Hoffmann P, Ludwig KU, Czamara D, St Pourcain B, Brandler W, Honbolygó F, Tóth D, Csépe V, Huguet G, Morris AP, Hulslander J, Willcutt EG, DeFries JC, Olson RK, Smith SD, Pennington BF, Vaessen A, Maurer U, Lyytinen H, Peyrard-Janvid M, Leppänen PHT, Brandeis D, Bonte M, Stein JF, Talcott JB, Fauchereau F, Wilcke A, Francks C, Bourgeron T, Monaco AP, Ramus F, Landerl K, Kere J, Scerri TS, Paracchini S, Fisher SE, Schumacher J, Nöthen MM, Müller-Myhsok B, Schulte-Körne G. Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Translational psychiatry 9 (2019), 1, article no 77, 15 Seiten, dx.doi.org/10.1038/s41398-019-0402-0
Godino N, Pfisterer F, Gerling T, Guernth-Marschner C, Duschl C, Kirschbaum M. Combining dielectrophoresis and computer vision for precise and fully automated single-cell handling and analysis. Lab on a Chip 24 (2019), 19, Seiten 4016-4020. dx.doi.org/10.1039/c9lc00800d
Golde T, Glaser M, Tutmarc C, Elbalasy I, Huster C, Busteros G, Smith DM, Herrmann H, Käs JA, Schnauß J. The role of stickiness in the rheology of semiflexible polymers. Soft matter 15 8 (2019), Seite 4865-4872, dx.doi.org/10.1039/C9SM00433E
Haange SB, Jehmlich N, Hoffmann M, Weber K, Lehmann J, von Bergen M, Slanina U. Disease development is accompanied by changes in bacterial protein abundance and functions in a refined model of dextran sulfate sodium (DSS)-induced colitis. Journal of proteome research 18 (2019), 4, Seite 1774-1786, dx.doi.org/10.1021/acs.jproteome.8b00974
Haehnel S, Reiche K, Loeffler D, Horn A, Blumert C, Puppel SH, Kaiser N, Rapp F, Rade M, Horn F, Meixensberger J, Bechmann I, Gaunitz F, Winter K. Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research. Sci Rep. 2019 Dec 27;9(1):19961
Hartlage-Rübsamen M, Ratz V, Zeitschel U, Finzel L, Machner L, Köppen J, Schulze A, Demuth HU, von Hörsten S, Höfling C, Rossner S. Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, coaggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer’s disease. Acta Neuropathologica Communications, (2019) 7:79
Hays JP, Mitsakakis K, Luz S, Van Belkum A, Becker K, Van den Bruel A, Harbarth S, Rex JH, Simonsen GS, Di Gregori V, Lüdke G, Van Staa T, Moran-Gilad J, Bachmann TT, JPIAMR AMR-RDT consortium. The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex »mix-and-match« implementation package. European Journal of Clinical Microbiology & Infectious Diseases 38 (2019), Seiten 1015–1022. dx.doi.org/10.1007/s10096-019-03492-4
Hillmann A, Paebst F, Brehm W, Piehler D, Schubert S, Tárnok A, Burk J. A novel direct co-culture assay analyzed by multicolor flow cytometry reveals context- and cell type-specific immunomodulatory effects of equine mesenchymal stromal cells. PLoS one 14 (2019), 6, 21 Seiten, dx.doi.org/10.1371/journal.pone.0218949
Huber R, Kirsten H, Näkki A, Pohlers D, Thude H, Eidner T, Heinig M, Brand K, Ahnert P, Kinne RW. Association of human FOS promoter variants with the occurrence of knee-osteoarthritis in a case control association study. International journal of molecular sciences 20 (2019), 6, 13 Seiten, dx.doi.org/10.3390/ijms20061382
Kämpf C, Specht M, Scholz A, Puppel SH, Doose G, Reiche K, Schor J, Hackermüller J. uap: reproducible and robust HTS data analysis. BMC Bionformatics, 20 (2019), 664, 9 Seiten. dx.doi.org/10.1186/s12859-019-3219-1
Kern K, Havenith H, Delaroque N, Rautenberger P, Lehmann J, Fischer M, Spiegel H, Schillberg S, Ehrentreich-Foerster E, Aurich S, Treudler R, Szardenings M. The immunome of soy bean allergy: comprehensive identification and characterization of epitopes. Clinical & experimental allergy 49 (2019), 2, Seite 239-251, dx.doi.org/10.1111/cea.13285
Kielar C, Xin Y, Xu X, Zhu S, Gorin N, Grundmeier G, Möser C, Smith DM, Keller A. Effect of staple age on DNA origami nanostructure assembly and stability. Molecules 24 (2019), 14, 12 Seiten, dx.doi.org/10.3390/molecules24142577
Kloess S, Kretschmer A, Stahl L, Fricke S, Koehl U. CAR-Expressing Natural Killer Cells for Cancer Retargeting. Transfus Med Hemother. 2019 Feb;46(1):4-13. dx.doi.org/10.1159/000495771
Kloess S, Oberschmidt O, Dahlke J, Vu XK, Neudoerfl C, Kloos A, Gardlowski T, Matthies N, Heuser M, Meyer J, Sauer M, Falk C, Koehl U, Schambach A, Morgan MA. Preclinical Assessment of Suitable Natural Killer Cell Sources for Chimeric Antigen Receptor Natural Killer-Based »Off-the-Shelf« Acute Myeloid Leukemia Immunotherapies. Human Gene Therapy 30 (2019), 4, Seiten 381-401. dx.doi.org/10.1089/hum.2018.247
Küster E, Kalkhof S, Aulhorn S, von Bergen M, Gündel U. Effects of five substances with different modes of action on cathepsin H, C and L activities in zebrafish embryos. International journal of environmental research and public health 16 (2019), 20, 15 Seiten, dx.doi.org/10.3390/ijerph16203956
Lienau C, Gräwert T, Alves Avelar LA, Illarionov B, Held J, Knaab TC, Lungerich B, van Geelen L, Meier D, Geissler S, Cynis H, Riederer U, Buchholz M, Kalscheuer R, Bacher A, Mordmüller B, Fischer M, Kurz T. Novel reverse thia-analogs of fosmidomycin: synthesis and antiplasmodial activity. European journal of medicinal chemistry 181 (2019), Artikel 111555, 12 Seiten, dx.doi.org/10.1016/j.ejmech.2019.07.058
Lordick F, Platzbecker U, Büch E et al. Molekulare und zellbasierte Krebstherapie – Quo vadis? Onkologe (2019). dx.doi.org/10.1007/s00761-019-0612-3
Luehr M, Bauernschmitt N, Peterss S, Li Y, Heyn O, Dashkevich A, Oberbach A, Bagaev E, Pichlmaier MA, Juchem G, Hagl C. Incidence and surgical outcomes of patients with native and prosthetic aortic valve endocarditis. Annals of Thoracic Surgery (2019) pre-proof. dx.doi.org/10.1016/j.athoracsur.2019.10.029
Mahmoud M, Laufer S, Deigner HP. Visual aptamer-based capillary assay for ethanolamine using magnetic particles and strand displacement. Mikrochimica acta 186 (2019), 11, 8 Seiten, dx.doi.org/10.1007/s00604-019-3795-9
Mahmoud M, Laufer S, Deigner HP. Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument. Data in brief 24 (2019), 103946, 11 Seiten, dx.doi.org/10.1016/j.dib.2019.103946
Mahmoud M, Laufer S, Deigner HP. An aptamer based thermofluorimetric assay for ethanolamine. Biochimie 158 (2019), Seite 233-237, dx.doi.org/10.1016/j.biochi.2019.01.014
Oberbach A, Friedrich M, Lehmann S, Schlichting N, Kullnick Y, Gräber S, Buschmann T, Hagl C, Bagaev E; CardiOmics group; Clinical Microbiology group; Bioinformatics group. Bacterial infiltration in structural heart valve disease. The journal of thoracic and cardiovascular surgery (2019), [Epub ahead of print], dx.doi.org/10.1016/j.jtcvs.2019.02.019
Oberbach A, Schlichting N, Friedrich M, Lehmann S, Kullnick Y, Pichlmaier M, Hagl C, Bagaev E; CardiOmics group; Clinical Microbiology group; Clinical; Management group. Quantification of Multiple Bacteria in Calcified Structural Valvular Heart Disease. Semin Thorac Cardiovasc Surg. 2019 Oct 9. pii: S1043-0679(19)30319-3. dx.doi.org/10.1053/j.semtcvs.2019.10.003
Oberbach A, Schlichting N, Kullnick Y, Heinrich M, Lehmann S, Retschlag U, Friedrich M, Fayad L, Dietrich A, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization improves blood pressure, renin and cardiovascular lipid deposition in a rat model of obesity. Endoscopy International Open 07 (2019), 11 Seiten. dx.doi.org/10.1055/a-0990-9683
Oberschmidt O, Morgan M, Huppert V, Kessler J, Gardlowski T, Matthies N, Aleksandrova K, Arseniev L, Schambach A, Koehl U, Kloess S. Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering. Hum Gene Ther Methods. 2019 Jun;30(3):102-120. dx.doi.org/10.1089/hgtb.2019.039. Epub 2019 May 16
Procházková L, Leya T, Křížková H, Nedbalová L. Sanguina nivaloides and Sanguina aurantia gen. et spp. nov. (Chlorophyta): the taxonomy, phylogeny, biogeography and ecology of two newly recognised algae causing red and orange snow. FEMS Microbiol. Ecol. 95(6), (2019), fiz064
Rauwald HW, Liebold T, Grötzinger K, Lehmann J, Kuchta K. Labdanum and Labdanes of Cistus creticus and C. ladanifer: anti-Borrelia activity and its phytochemical profiling. Phytomedicine 60 (2019), article 152977, dx.doi.org/10.1016/j.phymed.2019.152977
Rockstroh A, Moges B, Berneck BS, Sattler T, Revilla-Fernández S, Schmoll F, Pacenti M, Sinigaglia A, Barzon L, Schmidt-Chanasit J, Nowotny N, Ulbert S. Specific detection and differentiation of tick-borne encephalitis and West Nile virus induced IgG antibodies in humans and horses. Transboundary and emerging diseases 66 (2019), 4, 8 Seiten, dx.doi.org/10.1111/tbed.13205
Ruppert C, Phogat N, Laufer S, Kohl M, Deigner HP. A smartphone readout system for gold nanoparticle-based lateral flow assays: application to monitoring of digoxigenin. Mikrochimica acta 186 (2019), 2,9 Seiten, dx.doi.org/10.1007/s00604-018-3195-6
Sandetskaya N, Isserstedt-John N, Koelsch A, Schattschneider S, Kuhlmeier D. An integrated homogeneous SPARCL™ immunoassay for rapid biomarker detection on a chip. Analytical methods 11 (2019), 19, Seite 2542-2550, dx.doi.org/10.1039/c9ay00198k
Sass S, Stöcklein WFM, Klevesath A, Hurpin J, Menger M, Hille C. Binding affinity data of DNA aptamers for therapeutic anthracyclines from microscale thermophoresis and surface plasmon resonance spectroscopy. Analyst. 144 (2019), 20, S. 6064-6073
Schüttler A, Altenburger R, Ammar M, Bader-Blukott M, Jakobs G, Knapp J, Krüger J, Reiche K, Wu GM, Busch W. Map and model-moving from observation to prediction in toxicogenomics. GigaScience 8 (2019), 6, 22 Seiten, dx.doi.org/10.1093/gigascience/giz057
Simsek C, Ichkhanian Y, Fayad L, Steele KE, Schweitzer MA, Lamond K, Vosoughi K, Doshi J, Shah T, Oberbach A, Al-Sabban A, Gandsas A, Kalloo AN, Khashab MA, Kumbhari V. Secured lumen-apposing fully covered metallic stents for Stenoses in post-bariatric surgery patients. Obesity Surgery 29 (2019), Seiten 2695-2699. dx.doi.org/10.1007/s11695-019-03906-4
Sinet-Mathiot V, Smith GM, Romandini M, Wilcke A, Peresani M, Hublin JJ, Welker F. Combining ZooMS and zooarchaeology to study Late Pleistocene hominin behaviour at Fumane (Italy). Scientific reports 9 (2019), 1, article 12350, 13 Seiten, dx.doi.org/10.1038/s41598-019-48706-z
Stahl L, Duenkel A, Hilger N, Tretbar US, Fricke S. The epitope-specific anti-human CD4 antibody MAX.16H5 and its role in immune tolerance. Frontiers in immunology 10 (2019), article 1035, 12 Seiten, dx.doi.org/10.3389/fimmu.2019.01035
Szendy M, Kalkhof S, Bittrich S, Kaiser F, Leberecht C, Labudde D, Noll M. Structural change in GadD2 of Listeria monocytogenes field isolates supports nisin resistance. International journal of food microbiology 305 (2019), article 108240, dx.doi.org/10.1016/j.ijfoodmicro.2019.108240
Thabet A, Schmäschke R, Fertey J, Bangoura B, Schönfelder J, Lendner M, Ulbert S, Daugschies A. Eimeria tenella oocysts attenuated by low energy electron irradiation (LEEI) induce protection against challenge infection in chickens. Veterinary parasitology 266 (2019), Seite 18-26, dx.doi.org/10.1016/j.vetpar.2019.01.001
Ueberham E, Spiegel H, Havenith H, Rautenberger P, Lidzba N, Schillberg S, Lehmann J. Simplified tracking of a soy allergen in processed food using a monoclonal antibody-based sandwich ELISA targeting the soybean 2S albumin gly m 8. Journal of agricultural and food chemistry 67 (2019), 31, Seite 8660-8667, dx.doi.org/10.1021/acs.jafc.9b02717
Ulbert S. West Nile virus vaccines – current situation and future directions. Human vaccines & immunotherapeutics 15 (2019), 10, Seite 2337-2342, dx.doi.org/10.1080/21645515.2019.1621149
Valainis D, Dondl P, Foehr P, Burgkart R, Kalkhof S, Duda GN, van Griensven M, Poh PSP. Integrated additive design and manufacturing approach for the bioengineering of bone scaffolds for favorable mechanical and biological properties. Biomedical Materials 14 (2019), 6, Articel 065002, 14 Seiten. dx.doi.org/10.1088/1748-605X/ab38c6
Wagner M, Hänsel R, Reinke S, Richter J, Altenbuchinger M, Braumann UD, Spang R, Löffler M, Klapper W. Automated macrophage counting in DLBCL tissue samples. Biological procedures online 21 (2019), article 13, 18 Seiten, dx.doi.org/10.1186/s12575-019-0098-9
Walcher L, Müller C, Hilger N, Kretschmer A, Stahl L, Wigge S, Rengelshausen J, Müller AM, Fricke S. Effect of combined sublethal X-ray irradiation ancyclosporine a treatment in NOD scid gamma (NSG) mice. Experimental animals 68 (2019), 1, Seite 1-11, dx.doi.org/10.1538/expanim.18-0056
Wichmann G, Gaede C, Melzer S, Bocsi J, Henger S, Engel C, Wirkner K, Wenning JR, Wald T, Freitag J, Willner M, Kolb M, Wiegand S, Löffler M, Dietz A, Tárnok A. Discrimination of head and neck squamous cell carcinoma patients and healthy adults by 10-color flow cytometry: development of a score based on leukocyte subsets. Cancers 11 (2019), 6, article 814, 18 Seiten, dx.doi.org/10.3390/cancers11060814
Wilmschen S, Schneider S, Peters F, Bayer L, Issmail L, Bánki Z, Grunwald T, von Laer D, Kimpel J. RSV vaccine based on rhabdoviral vector protects after single. Vaccines 7 (2019), 3, article 59, 17 Seiten, dx.doi.org/10.3390/vaccines7030059
Wittenbrink N, Herrmann S, Blazquez-Navarro A, Bauer Ch, Lindberg E, Reinke P, Sawitzki B, Thomusch O, Hugo Ch, Babel N, Seitz H, Or-Guil M. A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection. BMC Immunology 20 (2019), Articel 11, 10 Seiten. dx.doi.org/10.1186/s12865-019-0291-2
Yakoub-Agha I, Chabannon C, Bader P, Basak GW, Bonig H, Ciceri F, Corbacioglu S, Duarte RF, Einsele H, Hudecek M, Kersten MJ, Köhl U, Kuball J, Mielke S, Mohty M, Murray J, Nagler A, Robinson S, Saccardi R, Sanchez-Guijo F, Snowden JA, Srour M, Styczynski J, Urbano-Ispizua A, Hayden PJ, Kröger N. Management of adults and children undergoing CAR t-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE). Haematologica. 2019 Nov 21. pii: haematol.2019.229781. dx.doi.org/10.3324/haematol.2019.229781
Yerebakan C, Boltze J, Elmontaser H, Yoruker U, Latus H, Khalil M, Ostermayer S, Steinbrenner B, Apitz C, Schneider M, Suchowski M, Ruetten R, Mueller K, Kerst G, Schranz D, Akintuerk H. Effects of pulmonary artery banding in doxorubicin-induced left ventricular cardiomyopathy. The journal of thoracic and cardiovascular surgery 157 (2019), 6, Seite 2416-2428, dx.doi.org/10.1016/j.jtcvs.2019.01.138
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Publikationen 2018

Andersen JL, Fagerberg R, Flamm C, Kianian R, Merkle D, Stadler PF. Towards mechanistic prediction of mass spectra using graph transformation. Match 80 (2018), Nr.3, S. 705-731. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_705-731.pdf
Andersen JL, Flamm C, Merkle D, Stadler PF. Rule composition in graph transformation models of chemical reactions. Match 80 (2018), Nr.3, S. 661-704. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_661-704.pdf
Bahner N, Reich P, Frense D, Menger M, Schieke K, Beckmann D. An aptamer-based biosensor for detection of doxorubicin by electrochemical impedance spectroscopy. Analytical and Bioanalytical Chemistry 410 (2018), 5, S. 1453-1462. dx.doi.org/10.1007/s00216-017-0786-8
Baqué M, Hanke F, Böttger U, Leya T, Moeller R, Vera JP de. Protection of cyanobacterial carotenoids‘ Raman signatures by Martian mineral analogues after high-dose gamma irradiation. Journal of Raman Spectroscopy 49 (2018), 10, S. 1617-1627. dx.doi.org/10.1002/jrs.5449
Bayer L, Fertey J, Ulbert S, Grunwald T. Immunization with an adjuvanted low-energy electron irradiation inactivated respiratory syncytial virus vaccine shows immunoprotective activity in mice. Vaccine 36 (2018), 12, S. 1561-1569. dx.doi.org/10.1016/j.vaccine.2018.02.014
Bayer L, Gümpel J, Hause G, Müller M, Grunwald T. Non-human papillomaviruses for gene delivery in vitro and in vivo. PLoS one 13 (2018), Art. e0198996, 14 S. dx.doi.org/10.1371/journal.pone.0198996
Behm LVJ, Schlenther I, Petrausch M, Jorde F, Godino N, Pfisterer F, Duschl C, Kirschbaum M. A simple approach for the precise measurement of surface temperature distributions on the microscale under dry and liquid conditions based on thin Rhodamine B films. Sensors and Actuators B-Chemical 255 (2018), S. 2023-2031. dx.doi.org/10.1016/j.snb.2017.09.001
Bender P, Egger A, Westermann M, Taudte N, Sculeana A, Potempa J, Möller B, Buchholz M, Eick S. Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis – A pilot study. Archives of Oral Biology, 97 (2019),S. 223-230. dx.doi.org/10.1016/j.archoralbio.2018.10.022
Blaess M, Bibak N, Claus RA, Kohl M, Bonaterra GA, Kinscherf R, Laufer S, Deigner HP. NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation. European journal of medicinal chemistry 153 (2018), S. 73-104. dx.doi.org/10.1016/j.ejmech.2017.09.021
Blod C, Schlichting N, Schülin S, Suttkus A, Peukert N, Stingu CS, Hirsch C, Elger W, Lacher M, Bühligen U, Mayer S. The oral microbiome - the relevant reservoir for acute pediatric appendicitis? International journal of colorectal disease 33 (2018), Nr.2, S. 209-218. dx.doi.org/10.1007/s00384-017-2948-8
Boltze J, Ferrara F, Hainsworth AH, Bridges LR, Zille M, Lobsien D, Barthel H, McLeod DD, Gräßer F, Pietsch S, Schatzl AK, Dreyer AY, Nitzsche B. Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage. Journal of cerebral blood flow and metabolism Cereb Blood Flow Metab. 2018 (vorab online). dx.doi.org/10.1177/0271678X18802119
Canzler S, Stadler PF, Schor J. The fungal snoRNAome. RNA 24 (2018), 3, S. 342-360. dx.doi.org/10.1261/rna.062778.117
Donath A, Stadler PF. Split-inducing indels in phylogenomic analysis. Algorithms for molecular biology. Online journal 13 (2018), Art. 12, 12 S. / dx.doi.org/10.1186/s13015-018-0130-7
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Dunkelmann T, Teichmann K, Ziehm T, Schemmert S, Frenzel D, Tusche M, Dammers C, Jürgens D, Langen KJ, Demuth HU, Shah NJ, Kutzsche J, Willuweit A, Willbold D. Aβ oligomer eliminating compounds interfere successfully with pEAβ(3–42) induced motor neurodegenerative phenotype in transgenic mice. Neuropeptides 67 (2018), S. 27-35. dx.doi.org/10.1016/j.npep.2017.11.011
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Gröger V, Cynis H. Human endogenous retroviruses and their putative role in the development of autoimmune disorders such as Multiple Sclerosis. Frontiers in Microbiology 9 (2018), 265. dx.doi.org/10.3389/fmicb.2018.00265
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Retzlaff N, Stadler PF. Phylogenetics beyond biology. Theory in Biosciences (2018), Online First, 11 S. dx.doi.org/10.1007/s12064-018-0264-7
Riemschneider S, Kohlschmidt J, Fueldner C, Esser C, Hauschildt S, Lehmann J. Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macrophages. Toxicology letters 296 (2018), S. 106-113. dx.doi.org/10.1016/j.toxlet.2018.07.050
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Publikationen 2017

Agocs E, Kozma P, Nador J, Hamori A, Janosov M, Kalas B, Kurunczi S, Fodor B, Ehrentreich-Förster E, Fried M, Horvath R, Petrik P. Grating coupled optical waveguide interferometry combined with in situ spectroscopic ellipsometry to monitor surface processes in aqueous solutions. Applied surface science 421 (2017), Pt. B, S. 289-294. dx.doi.org/10.1016/j.apsusc.2016.07.166
Ahn J-S, Kim H-J, Kim YK, Lee S-S, Ahn SY, Jung SH, Yang DH, Lee JJ, Park HJ, Choi SH, Jung CW, Jang JH, Kim HJ, Moon JH, Sohn SK, Won JH, Kim SH, Szardenings M, Minden M, Hwan K, Dennis D. 5-Hydro-xymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia. OncoTarget. 8 (2017), 5, S. 8305-8314. dx.doi.org/10.18632/oncotarget.14171
Al Arab M, Bernt M, Höner Zu Siederdissen C, Tout K, Stadler PF. Partially local three-way alignments and the sequence signatures of mitochondrial genome rearrangements. Algorithms for molecular biology. 12 (2017), 22, 11 S. dx.doi.org/10.1186/s13015-017-0113-0
Al-Arab M, Höner zu Siederdissen C, Tout KR, Sahyoun AH, Stadler PF, Bernt M. Accurate annotation of protein-coding genes in mitochondrial genomes. Molecular phylogenetics and evolution 106 (2017), S. 209-216. dx.doi.org/10.1016/j.ympev.2016.09.024
Ambrosius B, Faissner S, Guse K, von Lehe M, Grunwald T, Gold R, Grewe B, Chan A. Teriflunomide and mono-methylfumarate target HIV-induced neuro-inflammation and neurotoxicity. Journal of neuroinflammation 14 (2017), Art. 51, 10 S. dx.doi.org/10.1186/s12974-017-0829-2
Andersen JL, Flamm C, Merkle D, Stadler PF. An intermediate level of abstraction for computational systems chemistry. Philosphical Transactions of the Royal Society A. 375 (2017), 2109, 20160354. dx.doi.org/10.1098/rsta.2016.0354
Antonyan A, Schlenzig D, Schilling S, Naumann M, Sharoyan S, Mardanyan S, Demuth HU. Concerted action of dipeptidyl peptidase IV and glutaminyl cyclase results in formation of pyro-glutamate-modified amyloid peptides in vitro. Neurochemistry International. 113 (2018), S. 112-119. dx.doi.org/10.1016/j.neuint.2017.12.001
Backofen R, Engelhardt J, Erxleben A, Fallmann J, Grüning B, Ohler U, Rajewsky N, Stadler PF. RNA-bioinformatics: Tools, services and databases for the analysis of RNA-based regulation. Journal of biotechnology. 261 (2017), S. 76-84. dx.doi.org/10.1016/j.jbiotec.2017.05.019
Bahner N, Reich P, Frense D, Menger M, Schieke K, Beckmann D. An aptamer-based biosensor for detection of doxorubicin by electro-chemical impedance spectroscopy. Analytical and Bioanalytical Chemistry. 410 (2018), 5, S. 1453-1462. dx.doi.org/10.1007/s00216-017-0786-8
Behm LVJ, Schlenther I, Petrausch M, Jorde F, Godino N, Pfisterer F, Duschl C, Kirschbaum M. A simple approach for the precise measurement of surface temperature distributions on the microscale under dry and liquid conditions based on thin Rhodamine B films. Sensors and Actuators B-Chemical. 255 (2018), 2, S. 2023–2031. dx.doi.org/10.1016/j.snb.2017.09.001
Berkemer SJ, Hoffmann A, Murray CRA, Stadler PF. SMORE: Synteny Modulator of Repetitive Elements. Life (Basel). 7 (2017), 4, 42, 16 S. dx.doi.org/10.3390/life7040042
Binder S, Hösler N, Riedel D, Zipfel I, Buschmann T, Kämpf C, Reiche K, Burger R, Gramatzki M, Hackermüller J, Stadler PF, Horn F. STAT3-induced long noncoding RNAs in multiple myeloma cells display different properties in cancer. Scientific Reports. 7 (2017), 11, Art. 7976, 13 S. dx.doi.org/10.1038/s41598-017-08348-5
Buschmann, T. DNABarcodes: An R package for the systematic construction of DNA sample tags. Bioinformatics 33 (2017), 6, S. 920-922. dx.doi.org/10.1093/bioinformatics/btw759
Connor D, Danckert L, Hoppe S, Bier FF, von Nickisch-Rosenegk M. Epitope determination of immunogenic proteins of Neisseria gonorrhoeae. PLoS One. 12 (2017), 7, Art. E0180962. dx.doi.org/10.1371/journal.pone.0180962
Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O‘Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European journal of immunology. 47 (2017), 10, S. 1584-1797. dx.doi.org/10.1002/eji.201646632
Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J. Recent progress in translational research on neurovascular and neurodegenerative disorders. Restorative neurology and neuroscience 35 (2017),1, S. 87-103. dx.doi.org/10.3233/RNN-160690
Diehl R, Ferrara F, Müller C, Dreyer AY, McLeod DD, Fricke S, Boltze J. Immunosuppression for in vivo research: State-of-the-art protocols and experimental approaches. Cellular and molecular immunology 14 (2017), 2, S. 146-179. dx.doi.org/10.1038/cmi.2016.39
Dondapati SK, Wüstenhagen DA, Strauch E, Kubick S. Cell-free production of pore forming toxins: Functional analysis of thermostable direct hemolysin from Vibrio parahaemolyticus. Engineering in Life Sciences. (2017), 9 S. dx.doi.org/10.1002/elsc.201600259
Doß S, Potschka H, Doß F, Mitzner S, Sauer M. Hepatotoxicity of antimycotics used for invasive fungal infections: In vitro results. BioMed research international 2017 (2017), Art. 9658018, 10 S. dx.doi.org/10.1155/2017/9658018
Dunkelmann T, Teichmann K, Ziehm T, Schemmert S, Frenzel D, Tusche M, Dammers C, Jürgens D, Langen KJ, Demuth HU, Shah NJ, Kutzsche J, Willuweit A, Willbold D. Aβ oligomer eliminating compounds interfere successfully with pEAβ (3–42) induced motor neurodegenerative phenotype in transgenic mice. Neuropeptides, Nov 2017. dx.doi.org/10.1016/j.npep.2017.11.011
Ewe A, Panchal O, Pinnapireddy SR, Bakowsky U, Przybylski S, Temme A, Aigner A. Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo. Nanomedicine. Nanotechnology, biology and medicine 13 (2017), 1, S. 209-218. dx.doi.org/10.1016/j.nano.2016.08.005
Fandrich A, Buller J, Memczak H, Stöcklein W, Hinrichs K, Wischerhoff E, Schulz B, Laschewsky A, Lisdat F. Responsive polymer-electrode interface-study of its thermo- and pH-sensitivity and the influence of peptide coupling. Electrochimica Acta 229 (2017), S. 325-333. dx.doi.org/10.1016/j.electacta.2017.01.080
Findeiß S, Etzel M, Will S, Mörl M, Stadler PF. Design of Artificial Riboswitches as Biosensors. Sensors (Basel). 17 (2017), 9, 1990, 28 S. dx.doi.org/10.3390/s17091990
Fischbach J, Loh Q, Bier FF, Lim TS, Frohme M, Glökler J. Alizarin Red S for online pyrophosphate detection identified by a rapid screening method. Scientific Reports. 7 (2017), Art. 45085, 9 S. dx.doi.org/10.1038/srep45085
Fornefett J, Krause J, Klose K, Fingas F, Hassert R, Eisenberg T, Schrödl W, Grunwald T, Müller U, Baums CG. Comparative analysis of clinics, pathologies and immune responses in BALB/c and C57BL/6 mice infected with Streptobacillus moniliformis. Microbes and infection. 20 (2018), 2, S. 101-110. dx.doi.org/10.1016/j.micinf.2017.10.001
Frimmel S, Mitzner SR, Koball S. Immunoadsorption as a Long-Term Therapy in Recurrent Focal Segmental Glomerulosclerosis After Renal Transplantation. Therapeutic apheresis and dialysis. 21 (2017), 1, S. 108-109. dx.doi.org/10.1111/1744-9987.12487
Gessner C, Ruschpler P, Fricke S, Gillissen A, Hoheisel G, Lehmann J, Sack U. Analyses of exhaled breath condensate cytokines for identification of lung cancer. Journal of laboratory medicine 41 (2017), 4, S. 187-194. dx.doi.org/10.1515/labmed-2017-0054
Grochowska KM, Yuanxiang P, Bär J, Raman R, Brugal G, Sahu G, Schweizer M, Bikbaev A, Schilling S, Demuth HU, Kreutz MR. Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO reports 18 (2017), 4, S. 511-657. dx.doi.org/10.15252/embr.201643519
Hahn MB, Meyer S, Schröter MA, Seitz H, Kunte HJ, Solomun T, Sturm H. Direct electron irradiation of DNA in fully aqueous environment. Damage determination in combination with Monte Carlo simulations. Physical chemistry chemical physics. 19 (2017), S. 1798-1805. dx.doi.org/10.1039/C6CP07707B
Hainsworth AH, Allan SM, Boltze J, Cunningham C, Farris C, Head E, Ihara M, Isaacs JD, Kalaria RN, Lesnik Oberstein SA, Moss MB, Nitzsche B, Rosenberg GA, Rutten JW, Salkovic-Petrisic M, Troen AM. Translational models for vascular cognitive impairment: A review including larger species. BMC medicine 15 (2017), Nr. 1, Art. 16, 12 S. dx.doi.org/10.1186/s12916-017-0793-9
Hamidouche Z, Rother K, Przybilla J, Krinner A, Clay D, Hopp L, Fabian C, Stolzing A, Binder H, Charbord P, Galle J. Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity. Stem cells 35 (2017), 3, S. 694-704. dx.doi.org/10.1002/stem.2514
Havenith H, Kern K, Rautenberger P, Spiegel H, Szardenings M, Ueberham E, Lehmann J, Buntru M, Vogel S, Treudler R, Fischer R, Schillberg S. Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants. Biotechnology journal 12 (2017), 2, Art. 1600441, 10 S. dx.doi.org/10.1002/biot.201600441
Hoffmann A, Fallmann J, Mörl M, Stadler PF, Amman F. Accurate Mapping of tRNA Reads. Bioinformatics. 2017 [Epub ahead of print]. dx.doi.org/10.1093/bioinformatics/btx756
Hoffmann M, Schwertassek U, Seydel A, Weber K, Falk W, Hauschildt S, Lehmann J. A refined and translationally relevant model of chronic DSS colitis in BALB/c mice. Lab Anim. 2017 [Epub ahead of print]. dx.doi.org/10.1177/0023677217742681
Hoffmann M, Schwertassek U, Seydel A, Weber K, Hauschildt S, Lehmann J. Therapeutic efficacy of a combined sage and bitter apple phytopharmaceutical in chronic DSS-induced colitis. Scientific Reports. 7 (2017), 1, Art. 14214, 10 S.dx.doi.org/10.1038/s41598-017-13985-x
Hoffmann T, Meyer A, Heiser U, Kurat S, Böhme L, Kleinschmidt M, Bühring KU, Hutter-Paier B, Farcher M, Demuth HU, Lues I, Schilling, S. Glutaminyl cyclase inhibitor PQ912 improves cognition in mouse models of Alzheimer‘s disease - studies on relation to effective target occupancy. The journal of pharmacology and experimental therapeutics 362 (2017), 1, S. 119-130. dx.doi.org/10.1124/jpet.117.240614
Holden E, Tárnok A, Popescu G. Quantitative phase imaging for label-free cytometry. Cytometry. Part A 91 (2017), 5, S. 407-411. dx.doi.org/10.1002/cyto.a.23130
Indrischek H, Prohaska SJ, Gurevich VV, Gurevich EV, Stadler PF. Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes. BMC Evol Biol. 17 (2017), 163, 22 S. dx.doi.org/10.1186/s12862-017-1001-4
Jaimes Y, Naaldijk Y, Wenk K, Leovsky C, Emmrich F. Mesenchymal Stem Cell-Derived Microvesicles Modulate Lipopolysaccharides-Induced Inflammatory Responses to Microglia Cells. Stem Cells. 35 (2017), 3, S. 812-823. dx.doi.org/10.1002/stem.2541
Johnson AA, Naaldijk Y, Hohaus C, Meisel HJ, Krystel I, Stolzing A. Protective effects of alpha phenyl-tert-butyl nitrone and ascorbic acid in human adipose derived mesenchymal stem cells from differently aged donors. Aging 9 (2017), 2, S. 340-352. dx.doi.org/10.18632/aging.101035
Jung SH, Lee HJ, Lee YK, Yang DH, Kim HJ, Rhee JH, Emmrich F, Lee JJ. A phase I clinical study of autologous dendritic cell therapy in patients with relapsed or refractory multiple myeloma. Oncotarget. 8 (2017), S. 41538-41548. dx.doi.org/10.18632/oncotarget.14582
Kehlen A, Haegele M, Böhme L, Cynis H, Hoffmann T, Demuth HU. N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity. Bioscience Reports, 37 (2017), 4, Art.BSR20170712, 14 S. dx.doi.org/10.1042/BSR20170712
Kim TH, Tyndel MS, Zhang Z, Ahn J, Choi S, Szardenings M, Lipton J, Kim HJ, Hwan DKD. Exome sequencing reveals DNMT3A and ASXL1 variants associate with progression of chronic myeloid leukemia after tyrosine kinase inhibitor therapy. Leukemia research 59 (2017), S. 142-148. dx.doi.org/10.1016/j.leukres.2017.06.009
Kolora SR, Faria R, Weigert A, Schaffer S, Grimm A, Henle K, Sahyoun AH, Stadler PF, Nowick K, Bleidorn C, Schlegel M. The complete mitochondrial genome of Lacerta bilineata and comparison with its closely related congener L. Viridis. Mitochondrial DNA 28 (2017), Nr. 1, S. 116-118. dx.doi.org/10.3109/19401736.2015.1111349
Kubitschke H, Schnauß J, Nnetu KD, Warmt E, Stange R, Käs JA. Actin and microtubule networks contribute differently to cell response for small and large strains. New Journal of Physics, 19 (2017, 093003. dx.doi.org/10.1088/1367-2630/aa7658
Kunath J, Delaroque N, Szardenings M, Neundorf I, Straub RH. Sympathetic nerve repulsion inhibited by designer molecules in vitro and role in experimental arthritis. Life sciences 168 (2017), S. 47-53. dx.doi.org/10.1016/j.lfs.2016.11.009
Laux EM, Bier FF, Hölzel R. Electrode-based AC electrokinetics of proteins: A mini-review. Bioelectrochemistry. 120 (2018), S. 76-82. dx.doi.org/10.1016/j.bioelechem.2017.11.010
Lepik K, Annilo T, Kukuškina V; eQTLGen Consortium, Kisand K, Kutalik Z, Peterson P, Peterson H. C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis. PLoS Computional biology. 13 (2017), 9, Art. E1005766, 20 S. dx.doi.org/10.1371/journal.pcbi.1005766
Leven M, Knaab TC, Held J, Duffy S, Meister S, Fischli C, Meitzner D, Lehmann U, Lungerich B, Kuna K, Stahlke P, Delves MJ, Buchholz M, Winzeler EA, Avery VM, Mordmüller B, Wittlin S, Kurz T. 3-Hydroxy-N‘-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of Medicinal Chemistry, 60 (2017), 14, S. 6036-6044. dx.doi.org/10.1021/acs.jmedchem.7b00140
Lindner S, Gruhle K, Schmidt R, Garamus VM, Ramsbeck D, Hause G, Meister A, Sinz A, Drescher S. Azide-modified membrane lipids: Synthesis, properties, and reactivity. Langmuir, 33 (2017), 20, S. 4960-4973. dx.doi.org/10.1021/acs.langmuir.7b00228
Lukowski SW, Lloyd-Jones LR, Holloway A, Kirsten H, Hemani G, Yang J, Small K, Zhao J, Metspalu A, Dermitzakis ET, Gibson G, Spector TD, Thiery J, Scholz M, Montgomery GW, Esko T, Visscher PM, Powell JE. Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood. Nature Communications. 8 (2017), Art. 483, 10 S. dx.doi.org/10.1038/s41467-017-00473-z
Machné R, Murray DB, Stadler PF. Similarity-Based Segmentation of Multi-Dimensional Signals. Scientific Reports. 7 (2017), 12355, 11 S. dx.doi.org/10.1038/s41598-017-12401-8
Meinlschmidt P, Brode V, Sevenich R, Ueberham E, Schweiggert-Weisz U, Lehmann J, Rauh C, Knorr D, Eisner, P. High pressure processing assisted enzymatic hydrolysis - An innovative approach for the reduction of soy immunoreactivity. Innovative food science & emerging technologies 40 (2017), S. 58-67. dx.doi.org/10.1016/j.ifset.2016.06.022
Moreira-Soto A, Sarno M, Pedroso C, Netto EM, Rockstroh A, Luz E, Feldmann M, Fischer C, Bastos FA, Kümmerer BM, de Lamballerie X, Drosten C, Ulbert S, Brites C, Drexler JF. Evidence for congenital Zika virus infection from neutralizing antibody titers in maternal sera, Northeastern Brazil. The journal of infectious diseases. 216 (2017), 12, S. 1501-1504. dx.doi.org/10.1093/infdis/jix539
Müller B, Schaadt G, Boltze J, Emmrich F; LEGASCREEN Consortium, Skeide MA, Neef NE, Kraft I, Brauer J, Friederici AD, Kirsten H, Wilcke A. ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR. Brain Behavior. 7 (2017), 11, e00851. dx.doi.org/10.1002/brb3.851
Naaldijk Y, Jäger C, Fabian C, Leovsky C, Blüher A, Rudolph L, Hinze A, Stolzing A. Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice. Neuropathology and applied neurobiology 43 (2017), 4, S. 299-314. dx.doi.org/10.1111/nan.12319
Namasu CY, Katzerke C, Bräuer-Hartmann D, Wurm AA, Gerloff D, Hartmann JU, Schwind S, Müller-Tidow C, Hilger N, Fricke S, Christopeit M, Niederwieser D, Behre G. ABR, a novel inducer of transcription factor C/EBPα, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia. Oncotarget. 8 (2017), 61, S. 103626-103639. dx.doi.org/10.18632/oncotarget.22093
Neel NE, Müller B, Liebig J, Schaadt G, Grigutsch M, Gunter TC, Wilcke A, Kirsten H, Skeide MA, Kraft I, Kraus N, Emmrich F, Brauer J, Boltze J, Friederici AD. Dyslexia risk gene relates to representation of sound in the auditory brainstem. Developmental cognitive neuroscience 24 (2017), S. 63-71. dx.doi.org/10.1016/j.dcn.2017.01.008
Netto EM, Moreira-Soto A, Pedroso C, Höser C, Funk S, Kucharski AJ, Rockstroh A, Kümmerer BM, Sampaio GS, Luz E, Vaz SN, Dias JP, Bastos FA, Cabral R, Kistemann T, Ulbert S, de Lamballerie X, Jaenisch T, Brady OJ, Drosten C, Sarno M, Brites C, Drexler JF. High Zika Virus Seroprevalence in Salvador, Northeastern Brazil limits the potential for further outbreaks. MBio. 8 (2017), 6, Art. E01390-17. dx.doi.org/10.1128/mBio.01390-17
Nitzsche F, Müller C, Lukomska B, Jolkkonen J, Deten A, Boltze J. The MSC adhesion cascade - insights into homing and transendothelial migration. Stem Cells. 35 (2017), 6, S. 1446-1460. dx.doi.org/10.1002/stem.2614
Nowakowski A, Andrzejewska A, Boltze J, Nitzsche F, Cui LL, Jolkkonen J, Walczak P, Lukomska B, Janowski M. Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells. Scientific Reports 7 (2017), Art. 1103, 12 S. dx.doi.org/10.1038/s41598-017-01304-3
Oberbach A, Schlichting N, Feder S, Lehmann S, Kullnick Y, Buschmann T, Blumert C, Horn F, Neuhaus J, Neujahr R, Bagaev E, Hagl C, Pichlmaier M, Rodloff AC, Gräber S, Kirsch K, Sandri M, Kumbhari V, Behzadi A, Behzadi A, Correia JC, Mohr FW, Friedrich M. New insights into valve-related intramural and intracellular bacterial diversity in infective endocarditis. PLoS one. 12 (2017), 4, Art. e0175569, 20 S. dx.doi.org/10.1371/journal.pone.0175569
Oberbach A, Schlichting N, Heinrich M, Kullnick Y, Retschlag U, Lehmann S, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism in obese rats. Gastrointestinal endoscopy. 87 (2018), 1, S. 288-299.e6. dx.doi.org/10.1016/j.gie.2017.04.038
Oswald L, Grosser S, Smith DM, Kaes JA. Jamming transitions in cancer. Journal of Physics D: Applied Physics. 50 (2017), 48, Art. 483001. dx.doi.org/10.1088/1361-6463/aa8e83
Piechotta A, Parthier C, Kleinschmidt M, Gnoth K, Pillot T, Lues I, Demuth HU, Schilling S, Rahfeld JU, Stubbs M. Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy. Journal of biological chemistry. 292 (2017), S. 12713-12724. dx.doi.org/10.1074/jbc.M117.777839
Pott J, Burkhardt R, Beutner F, Horn K, Teren A, Kirsten H, Holdt LM, Schuler G, Teupser D, Loeffler M, Thiery J, Scholz M. Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery. Atherosclerosis. 259 (2017), S. 32-40. dx.doi.org/10.1016/j.atherosclerosis.2017.02.018
Prohaska SJ, Berkemer SJ, Gärtner F, Gatter T, Retzlaff N; Students of the Graphs and Biological Networks Lab 2017, Höner Zu Siederdissen C, Stadler PF. Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem. J Math Biol. 2017 Dec 19. http://dx.doi.org/10.1007/s00285-017-1197-3
Przybylski S, Gasch M, Marschner A, Ebert M, Ewe A, Helmig G, Hilger N, Fricke S, Rudzok S, Aigner A, Burkhardt J. Influence of nanoparticle-mediated transfection on proliferation of primary immune cells in vitro and in vivo. PLoS one. 12 (2017), 5, Art. e0176517, 16 S. dx.doi.org/10.1371/journal.pone.0176517
Ramsbeck D, Hamann A, Schlenzig D, Schilling S, Buchholz M. First insight into structure-activity relationships of selective Meprin ß inhibitors. Bioorganic & Medicinal Chemistry Letters. 27 (2017), 11, S. 2428-2431. dx.doi.org/10.1016/j.bmcl.2017.04.012
Rockstroh A, Moges B, Barzon L, Sinigaglia A, Palù G, Kumbukgolla W, Schmidt-Chanasit J, Sarno M, Brites C, Moreira-Soto A, Drexler JF, Ferreira OC, Ulbert S. Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop. Emerging microbes and infections. 6 (2017), Art. E99, 9 S. dx.doi.org/10.1038/emi.2017.87
Rodewohl A, Scholbach J, Leichsenring A, Köberle M, Lange F. Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. Innate immunity. 23 (2017), 3, S. 258-275. dx.doi.org/10.1177/1753425917690814
Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. (2017), gutjnl-2017-314454. dx.doi.org/10.1136/gutjnl-2017-314454
Sajfutdinow M, Uhlig K, Prager A, Schneider C, Abel B, Smith DM. Nanoscale patterning of self-assembled monolayer (SAM)-functionalised substrates with singlemolecule contact printing. Nanoscale. 39 (2017), 9, S. 15098-15106. dx.doi.org/10.1039/C7NR03696E
Sandetskaya N, Moos D, Pötter H, Seifert S, Jenerowicz M, Becker H, Zilch C, Kuhlmeier D. An integrated versatile lab-on-a-chip platform for the isolation and nucleic acid-based detection of pathogens. Future Science OA 3 (2017), 2, Art. FSO177, 13 S. dx.doi.org/10.4155/fsoa-2016-0088
Schnauß J, Glaser M, Lorenz JS, Schuldt C, Möser C, Sajfutdinow M, Haendler T, Kaes JA, Smith DM. DNA nanotubes as a versatile tool to study semiflexible polymers. Journal of Visualized Experiments JoVE. (2017), 128. dx.doi.org/10.3791/56056
Schneevoigt J, Fabian C, Leovsky C, Seeger J, Bahramsoltani M. In vitro expression of the extracellular matrix components aggrecan, collagen types I and II by articular cartilage-derived chondrocytes. Anatomia, histologia, embryologia 46 (2017), 1, S. 43-50. dx.doi.org/10.1111/ahe.12230
Schüttler A, Reiche K, Altenburger R, Busch W. The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis. Toxicological Sciences. 157 (2017), 2, S. 291-304. dx.doi.org/10.1093/toxsci/kfx045
Sonnabend A, Spahn V, Stech M, Zemella A, Stein C, Kubick S. Production of G protein-coupled receptors in an insect-based cell-free system. Biotechnology and bioengineering. 114 (2017), 10, S. 2328–2338. dx.doi.org/10.1002/bit.26346
Soria J, Acera A, Merayo-LLoves J, Durán JA, González N, Rodriguez S, Bistolas N, Schumacher S, Bier FF, Peter H, Stöcklein W, Suárez T. Tear proteome analysis in ocular surface diseases using label-free LC-MS/MS and multiplexed-microarray biomarker validation. Scientific Reports. 7 (2017), Art. 17478, 15 S. . http://dx.doi.org/10.1038/s41598-017-17536-2
Spahn C, Wermann M, Eichentopf R, Hause G, Schlenzig D, Schilling S. Purification of recombinant Aβ(1-42) and pGlu-Aβ(3-42) using preparative SDS-PAGE. Electrophoresis 38 (2017), 16, S. 2042-2049. dx.doi.org/10.1002/elps.201700154
Stamenković S, Dučić T, Stamenković V, Kranz A, Andjus PR. Imaging of glial cell morphology, SOD1 distribution and elemental composition in the brainstem and hippocampus of the ALS hSOD1G93A rat. Neuroscience 357 (2017), S. 37-55. dx.doi.org/10.1016/j.neuroscience.2017.05.041
Stech M, Nikolaeva O, Thoring L, Stöcklein WFM, Wüstenhagen DA, Hust M, Dübel S, Kubick S. Cell-free synthesis of functional antibodies using a coupled in vitro transcription-Translation system based on CHO cell lysates. Scientific Reports. 7 (2017), Art. 12030, 15 S. dx.doi.org/10.1038/s41598-017-12364-w
Stephan A, Hahn-Löbmann S, Rosche F, Buchholz M, Giritch A, Gleba Y. Simple purification of Nicotiana benthamiana-produced recombinant colicins: High-yield recovery of purified proteins with minimum alkaloid content supports the suitability of the host for manufacturing food additives. International Journal of Molecular Sciences. 19 (2017). 1, Art. 95, 13 S. dx.doi.org/10.3390/ijms19010095
Strehle D, Mollenkopf P, Glaser M, Golde T, Schuldt C, Käs JA, Schnauß J. Single actin bundle rheology. Molecules. 22 (2017), 10, Art. 1804, 12 S. dx.doi.org/10.3390/molecules22101804
Teren A, Kirsten H, Beutner F, Scholz M, Holdt LM, Teupser D, Gutberlet M, Thiery J, Schuler G, Eitel, I. Alteration of multiple leukocyte gene expression networks is linked with magnetic resonance markers of prognosis after acute ST-Elevation myocardial infarction. Scientific Reports 7 (2017), Art. 41705, 10 S. dx.doi.org/10.1038/srep41705
Thalheim T, Quaas M, Herberg M, Braumann UD, Kerner C, Loeffler M, Aust G, Galle J. Linking stem cell function and growth pattern of intestinal organoids. Developmental Biology. 433 (2018), 2, S. 254-261. dx.doi.org/10.1016/j.ydbio.2017.10.013
Theuß T, Ueberham E, Lehmann J, Lindner T, Springer S. Immunogenic potential of a Salmonella Typhimurium live vaccine for pigs against monophasic Salmonella Typhimurium DT 193. BMC Vetinary Research. 13 (2017), 1, Art. 343, 8 S. dx.doi.org/10.1186/s12917-017-1271-5
Thoring L, Dondapati SK, Stech M. High-yield production of »difficult-to-express« proteins in a continuous exchange cell-free system based on CHO cell lysates. Scientific Reports. 7 (2017), Art, 11710. dx.doi.org/10.1038/s41598-017-12188-8
Valach M, Moreira S, Hoffmann S, Stadler PF, Burger G. Keeping it complicated: Mitochondrial genome plasticity across diplonemids. Scientific Reports. 7 (2017), 1, 14166, 12 S. dx.doi.org/10.1038/s41598-017-14286-z
Wurm AA, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer-Hartmann D, Katzerke C, Hartmann JU, Benoukraf T, Fricke S, Hilger N, Müller AM, Bill M, Schwind S, Tenen DG, Niederwieser D, Alberich-Jorda M, Behre G. Disruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation. Nature Communications. 8 (2017), Art. 46. 16 S. dx.doi.org/10.1038/s41467-017-00032-6
Zemella A, Grossmann S, Sachse R, Sonnabend A, Schaefer M, Kubick S. Qualifying a eukaryotic cell-free system for fluorescence based GPCR analyses. Scientific Reports 7 (2017), Art. 3740, 10 S. dx.doi.org/10.1038/s41598-017-03955-8

Publikationen 2016

Bader D, Klier DT, Hettrich C, Bier FF, Wessig P. Detecting carbohydrate–lectin interactions using a fluorescent probe based on DBD dyes. Anal. Methods. 2016 Jan 13; 8, 1235-1238: DOI dx.doi.org/10.1039/C5AY02991K
Bavli D, Prill S, Ezra E, Levy G, Cohen M, Vinken M, Vanfleteren J, Jaeger M, Nahmias Y. Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction. Proceedings of the National Academy of Sciences of the United States of America : PNAS. 113 (2016), 16, S. E2231-E2240. dx.doi.org/10.1073/pnas.1522556113
Becker A, Eichentopf R, Sedlmeier R, Cynis H, Koch B, Stephan A, Bäuscher Ch, Kohlmann S, Hoffmann T, Kehlen A, Berg S, Freyse EJ, Osmand A, von Hörsten St, Graubner S, Demuth HU, Schilling S. IsoQC (QPCTL) knock out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes. Biological Chemistry. 397 (2016), 1, S. 45-55. dx.doi.org/10.1515/hsz-2015-0192
Boltze J, Wagner DC, Barthel H, Gounis M. Academic-industry collaborations in translational stroke research. Translational Stroke Research. 7 (2016), 4, S. 343-353. dx.doi.org/10.1007/s12975-016-0475-5
Boltze J, Ayata C. Challenges and controversies in translational stroke research : An introduction. Editorial. Translational Stroke Research. 7 (2016), 5, S. 355-357. dx.doi.org/10.1007/s12975-016-0492-4
Boltze J, Wagner DC, Henninger N, Plesnila N, Ayata C. Phase III preclinical trials in translational stroke research : community response on framework and guidelines. Translational Stroke Research. 7 (2016), 4, S. 241-247. dx.doi.org/10.1007/s12975-016-0474-6
Brameshuber M, Sevcsik E, Rossboth BK, Manner C, Deigner HP, Peksel B, Péter M, Török Z, Hermetter A, Schütz GJ. Oxidized phospholipids inhibit the formation of cholesterol-dependent plasma membrane nanoplatforms. Biophysical journal. 110 (2016), 1, S. 205-213. dx.doi.org/10.1016/j.bpj.2015.11.018
Canzler S, Stadler PF, Hertel J. U6 snRNA intron insertion occurred multiple times during fungi evolution. RNA biology. 13 (2016), 2, S. 119-127. dx.doi.org/10.1080/15476286.2015.1132139
Connor DO, Zantow J, Hust M, Bier FF, von Nickisch-Rosenegk M. Identification of novel immunogenic proteins of Neisseria gonorrhoeae by phage display. PLoS One. 11 (2016), Nr. 2, Art. e0148986, 24 S. dx.doi.org/10.1371/journal.pone.0148986
Corrales Ureña YR, Lisboa-Filho PN, Szardenings M, Gätjen L, Noeske, P LM, Rischka K. Formation and composition of adsorbates on hydrophobic carbon surfaces from aqueous laccase-maltodextrin mixture suspension. Applied surface science. 385 (2016), S. 216-224. dx.doi.org/10.1016/j.apsusc.2016.05.097
Couturier J-P, Wischerhoff E, Benin R, Hettrich C, Koetz J, Sütterlin M, Tiersch B, Laschewsky A. Thermoresponsive Polymers and Inverse Opal Hydrogels for the Detection of Diols. Langmuir. 32 (2016) 4333-4345: DOI dx.doi.org/10.1021/acs.langmuir.6b00803
Cui LL, Kinnunen T, Boltze J, Nystedt J, Jolkkonen J. Clumping and viability of bone marrow derived mesenchymal stromal cells under different preparation procedures : A flow cytometry-based in vitro study. Stem Cells International. (2016), Art. 1764938, 8 S. dx.doi.org/10.1155/2016/1764938
Cynis H, Frost JL, Crehan H, Lemere CA. Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges. Molecular neurodegeneration. 11 (2016), Art. 48, 11 S. dx.doi.org/10.1186/s13024-016-0115-2
Domin G, Findeiß S, Wachsmuth M, Will S, Stadler PF, Mörl M. Applicability of a computational design approach for synthetic riboswitches. Nucleic Acids Research, 2016 Dec 19, pii: gkw1267. (Epub ahead of print]. dx.doi.org/10.1093/nar/gkw1267
Ewe A, Przybylski S, Burkhardt J, Janke A, Appelhans D, Aigner A. A novel tyrosine-modified low molecular weight polyethylenimine (P10Y) for efficient siRNA delivery in vitro and in vivo. J Control Release. 2016 May 28;230:13-25. DOI dx.doi.org/10.1016/j.jconrel.2016.03.034. Epub 2016 Apr 7.
Feoktistova N, Rose J, Prokopović VZ, Vikulina AS, Skirtach A, Volodkin D. Controlling the vaterite CaCO3 crystal pores : Design of tailor-made polymer based microcapsules by hard templating. Langmuir. The ACS journal of surfaces and colloids. 32 (2016), 17, S. 4229-4238. dx.doi.org/10.1021/acs.langmuir.6b00717
Fertey J, Bayer L, Grunwald T, Pohl A, Beckmann J, Gotzmann G, Casado JP, Schönfelder J, Rögner FH, Wetzel C, Thoma M, Bailer SM, Hiller E, Rupp S, Ulbert S. Pathogens Inactivated by Low-Energy-Electron Irradiation Maintain Antigenic Properties and Induce Protective Immune Responses. Viruses. 2016 Nov 23;8(11). pii: E319.
Flemmig J, Schwarz P, Bäcker I, Leichsenring A, Lange F, Arnhold J. Fast and Specific Assessment of the Halogenating Peroxidase Activity in Leukocyte-enriched Blood Samples. J. Vis. Exp. (2016), e54484, View video paper
Georgi V, Georgi L, Blechert M, Bergmeister M, Zwanzig M, Wüstenhagen DA, Bier FF, Jung E, Kubick S. On-chip automation of cell-free protein synthesis: new opportunities due to a novel reaction mode. Lab Chip. 2016 Jan 5;16(2):269-81. DOI dx.doi.org/10.1039/c5lc00700c.
Glaser M, Schnauß J, Tschirner T, Schmidt S, Moebius-Winkler M, Käs J, Smith DM. Self-assembly of hierarchically ordered structures in DNA nanotube systems. New journal of physics. 18 (2016), Art. 055001, 14 S. dx.doi.org/10.1088/1367-2630/18/5/055001
Habaza M, Kirschbaum M, Guernth-Marschner C, Dardikman G, Barnea I, Korenstein R, Duschl C, Shaked NT. Rapid 3D refractive-index imaging of live cells in suspension without labeling using dielectrophoretic cell rotation. Advanced Science. (2016), 1600205, 9 S. dx.doi.org/10.1002/advs.201600205
Haid S, Grethe C, Bankwitz D, Grunwald T, Pietschmann T. Identification of a human respiratory syncytial virus cell entry inhibitor by using a novel lentiviral pseudotype system. Journal of virology. 90 (2016), Nr. 6, S. 3065-3073. dx.doi.org/10.1128/JVI.03074-15
Hamidouche Z, Rother K, Przybilla J, Krinner A, Clay D, Hopp L, Fabian C, Stolzing A, Binder H, Charbord P, Galle J. Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity. Stem Cells. 2016 Oct 13. [Epub ahead of print]. dx.doi.org/10.1002/stem.2514
Heathman TR, Stolzing A, Fabian C, Rafiq QA, Coopman K, Nienow AW, Kara B, Hewitt CJ. Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate. Cytotherapy. 18 (2016), 4, S. 523-535. dx.doi.org/10.1016/j.jcyt.2016.01.007
Hezaveh K, Kloetgen A, Bernhart SH, Mahapatra KD, Lenze D, Richter J, Haake A, Bergmann AK, Brors B, Burkhardt B, Claviez A, Drexler HG, Eils R, Haas S, Hoffmann S, Karsch D, Klapper W, Kleinheinz K, Korbel J, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Leich E, Loeffler M, Mantovani-Loeffler L, López C, McHardy AC, Möller P, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schlesner M, Scholz I, Stadler PF, Stilgenbauer S, Sungalee S, Szczepanowski M, Trümper L, Weniger MA, Siebert R, Borkhardt A, Hummel M, Hoell JI; ICGC MMML-Seq Project group. Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis. Haematologica. 101 (2016), 11, S. 1380-1389. dx.doi.org/10.3324/haematol.2016.143891
Hielscher-Michael S, Griehl C, Buchholz M, Demuth HU, Arnold N, Wessjohann LA. Natural products from microalgae with potential against Alzheimer’s disease: sulfolipids are potent glutaminyl cyclase inhibitors. Mar Drugs. 2016 Nov 2;14(11). pii: E203. dx.doi.org/10.3390/md14110203
Hilger N, Glaser J, Müller C, Halbich C, Müller A, Schwertassek U, Lehmann J, Ruschpler P, Lange F, Boldt A, Stahl L, Sack U, Oelkrug C, Emmrich F, Fricke S. Attenuation of graft-versus-host-disease in NOD scid IL-2Rγ-/- (NSG) mice by ex vivo modulation of human CD4+ T cells. Cytometry Part A. 89 (2016), 9, S. 803 - 817. dx.doi.org/10.1002/cyto.a.22930
Hill K, Fiorito S, Taddeo VA, Schulze A, Leonhardt M, Epifano F, Genovese S. Plumbagin, Juglone, and Boropinal as novel TRPA1 agonists. Journal of natural products. 79 (2016), 4, S .697-703. dx.doi.org/10.1021/acs.jnatprod.5b00396
Indrischek H, Wieseke N, Stadler PF, Prohaska SJ. The paralog-to-contig assignment problem : high quality gene models from fragmented assemblies. Algorithms for molecular biology. 11 (2016), Art. 1, 14 S. dx.doi.org/10.1186/s13015-016-0063-y
Jaimes Y, Naaldijk Y, Wenk K, Leovsky C, Emmrich F. Mesenchymal stem cell-derived microvesicles modulate LPS-induced inflammatory responses to microglia cells. StemCells. 2016 Nov 16. dx.doi.org/10.1002/stem.2541
Jorjani H, Kehr S, Jedlinski DJ, Gumienny R, Hertel J, Stadler PF, Zavolan M, Gruber AR. An updated human snoRNAome. Nucleic Acids Research. 44 (2016), 11, S. 5068-5082. dx.doi.org/10.1093/nar/gkw386
Jühling F, Kretzmer H, Bernhart SH, Otto C, Stadler PF, Hoffmann S. Metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data. Genome research. 26 (2016), 2, S. 256-262. dx.doi.org/10.1101/gr.196394.115
Kalkhof S, Schildbach S, Blumert C, Horn F, von Bergen M, Labudde D. PIPINO: A software package to facilitate the identification of protein-protein interactions from affinity purification mass spectrometry data. BioMed research international. (2016), Art. 2891918, 13 S. dx.doi.org/10.1155/2016/2891918
Kang MG, Kim YN, Lee JH, Szardenings M, Baek HJ, Kook H, Kim HR, Shin MG. Clinicopathological implications of mitochondrial genome alterations in pediatric acute myeloid leukemia. Annals of laboratory medicine. 36 (2016), 2, S. 101-110. dx.doi.org/10.3343/alm.2016.36.2.101
Keller KC, Ding H, Tieu R, Sparks NR, Ehnes DD, Zur Nieden N. Wnt5a supports osteogenic lineage decisions in embryonic stem cells. Stem cells and development. 25 (2016), 13, S. 1020-1032. dx.doi.org/10.1089/scd.2015.0367
Kleinschmidt M, Schoenfeld R, Göttlich C, Bittner D, Metzner JE, Leplow B, Demuth HU. Characterizing aging, mild cognitive impairment, and Dementia with blood-based biomarkers and neuropsychology. Journal of Alzheimer‘s disease. 50 (2016), 1, S. 111-26. dx.doi.org/10.3233/JAD-143189
Kraft I, Schreiber J, Cafiero R, Metere R, Schaadt G, Brauer J, Neef NE, Müller B, Kirsten H, Wilcke A, Boltze J, Friederici AD, Skeide MA. Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI. Neuroimage. 143 (2016), S. 378-386. dx.doi.org/10.1016/j.neuroimage.2016.09.004
Krakauer DC, Müller L, Prohaska SJ, Stadler PF. Design specifications for cellular regulation. Theory in biosciences. 135 (2016), 4, S. 231-240. dx.doi.org/10.1007/s12064-016-0239-5
Kucharík M, Hofacker IL, Stadler PF, Qin J. Pseudoknots in RNA folding landscapes. Bioinformatics. 32 (2016), 2, S. 187-194. dx.doi.org/10.1093/bioinformatics/btv572
Laube M, Stolzing A, Thome UH, Fabian C. Therapeutic potential of mesenchymal stem cells for pulmonary complications associated with preterm birth. The international journal of biochemistry & cell biology. 74 (2016), S. 18-32. dx.doi.org/10.1016/j.biocel.2016.02.023
Laux EM, Knigge X, Bier FF, Wenger C, Hölzel R. Aligned immobilization of proteins using AC electric fields. Small. 12 (2016), 11, S. 1514-1520. dx.doi.org/10.1002/smll.201503052
Leichsenring A, Bäcker I, Furtmüller PG, Obinger C, Lange F, Flemmig J. Long-term effects of (-)-Epigallocatechin Gallate (EGCG) on Pristane-Induced Arthritis (PIA) in female dark agouti rats. PLoS one. 11 (2016), 3, Art. e0152518, 27 S. dx.doi.org/10.1371/journal.pone.0152518
Leontyev S, Davierwala PM, Krögh G, Feder S, Oberbach A, Bakhtiary F, Misfeld M, Borger MA, Mohr FW. Early and late outcomes of complex aortic root surgery in patients with aortic root abscesses†. Eur J Cardiothorac Surg. 2016 Feb;49(2):447-55.
Lipka J, Semmler-Behnke M, Wenk A, Burkhardt J, Aigner A, Kreyling W. Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments. Data in Brief 7 (2016), pp.1175-1178. DOI dx.doi.org/10.1016/j.dib.2016.03.092
Lipka J, Semmler-Behnke M, Wenk A, Burkhardt J, Aigner A, Kreyling W. Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice. Int J Pharm. 2016 Mar 16;500(1-2):227-35. DOI dx.doi.org/10.1016/j.ijpharm.2016.01.038. Epub 2016 Jan 21.
Lipka J, Semmler-Behnke M, Wenk A, Burkhardt J, Aigner A, Kreyling W. Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments. Data in Brief. 7 (2016), S. 1175-1178. dx.doi.org/10.1016/j.dib.2016.03.092
Lohmann G, Stelzer J, Zuber V, Buschmann T, Margulies D, Bartels A, Scheffler K. Task-related edge density (TED) - a new method for revealing dynamic network formation in fMRI data of the human brain. PLoS One. 11 (2016), 6, Art. e0158185, 22 S. dx.doi.org/10.1371/journal.pone.0158185
Lorenz R, Hofacker IL, Stadler PF. RNA folding with hard and soft constraints. Algorithms for molecular biology. 11(2016), Art. 8, 13 S. dx.doi.org/10.1186/s13015-016-0070-z
Makert GR, Vorbrüggen S, Krautwald-Junghanns ME, Voss M, Sohn K, Buschmann T, Ulbert S. A method to identify protein antigens of Dermanyssus gallinae for the protection of birds from poultry mites. Parasitol Res. 2016 Jul;115(7):2705-13. DOI dx.doi.org/10.1007/s00436-016-5017-2
Meinlschmidt P, Ueberham E, Lehmann J, Schweiggert-Weisz U, Eisner P. Immunoreactivity, sensory and physicochemical properties of fermented soy protein isolate. Food chemistry. 205 (2016), S. 229-238. dx.doi.org/10.1016/j.foodchem.2016.03.016
Memczak H, Lauster D, Kar P, Di Lella S, Volkmer R, Knecht V, Herrmann A, Ehrentreich-Förster E, Bier FF, Stöcklein WF. Anti-hemagglutinin antibody derived lead peptides for inhibitors of influenza virus binding. PLoS One. 11 (2016), 7, Art. e0159074, 24 S. dx.doi.org/10.1371/journal.pone.0159074
Menger M, Yarman A, Erdőssy J, Yildiz HB, Gyurcsányi RE, Scheller FW. MIPs and Aptamers for Recognition of Proteins in Biomimetic Sensing. Biosensors (Basel). 2016 Jul 18;6(3). pii: E35. DOI dx.doi.org/10.3390/bios6030035 Article
Min-Gu K, Hyun-Woo C, Jun Hyung L, Yong Jun C, Hyun-Jung C, Jong-Hee S, Soon-Pal S, Szardenings M, Hye-Ran K, Myung-Geun S. Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemia. OncoTarget. 7 (2016), 35, S. 57036-57049. dx.doi.org/10.18632/oncotarget.10958
Morschheuser L, Mükusch S, Riedner M, Seitz H, Rohn S. High-performance thin-layer chromatography as a fast screening tool for phosphorylated peptides. Journal of chromatography B: Analytical technologies in the biomedical and life sciences. 1008 (2016), S. 198-205. dx.doi.org/10.1016/j.jchromb.2015.11.055
Müller B, Wilcke A, Boulesteix AL, Brauer J, Passarge E, Boltze J, Kirsten H. Improved prediction of complex diseases by common genetic markers: State of the art and further perspectives. Human genetics. 135 (2016), 3, S. 259-272. dx.doi.org/10.1007/s00439-016-1636-z
Müller B, Wilcke A, Czepezauer I, Ahnert P, Boltze J, Kirsten H, Friederici AD, Emmrich F, Brauer J, Neef N, Skeide MA, Schaadt G, Kraft I, Dörr L. Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort. Scientific Report. 6 (2016), Art. 27901, 11 S. dx.doi.org/10.1038/srep27901
Naaldijk Y, Friedrich-Stöckigt A, Sethe S, Stolzing A. Comparison of different cooling rates for fibroblast and keratinocyte cryopreservation. Journal of tissue engineering and regenaritive medicine. (2016), 10, S. E354 - E364. dx.doi.org/10.1002/term.1815
Naaldijk Y, Jager C, Fabian C, Leovsky C, Bluher A, Rudolph L, Hinze A, Stolzing A. Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1. Alzheimer mice. Neuropathology and applied neurobiology. 2016 Feb 26. [Epub ahead of print]. dx.doi.org/10.1111/nan.12319
Nitzsche B, Barthel H, Lobsien D, Boltze J, Zeisig V, Dreyer AY. Focal cerebral ischemia by permanent middle cerebral artery occlusion in sheep: Surgical technique, clinical imaging, and histopathological results. Neuromethods. 116 (2016), S. 195 - 225. dx.doi.org/10.1007/978-1-4939-3730-1_15
Oberbach A, Adams V, Schlichting N, Heinrich M, Kullnick Y, Lehmann S, Lehmann S, Feder S, Correia JC, Mohr FW, Völker U, Jehmlich N. Proteome profiles of HDL particles of patients with chronic heart failure are associated with immune response and also include bacteria proteins. Clin Chim Acta. 2016 Jan 30;453:114-22. DOI dx.doi.org/10.1016/j.cca.2015.12.005
Park SH, Zheng JH, Nguyen VH, Jiang SN, Kim DY, Szardenings M, Min JH, Hong Y, Choy HE, Min JJ. RGD peptide cell-surface display enhances the targeting and therapeutic efficacy of attenuated Salmonella-mediated cancer therapy. Theranostics. 6 (2016), 10, S. 1672-82. dx.doi.org/10.7150/thno.16135
Patra Bhattacharya D, Canzler S, Kehr S, Hertel J, Grosse I, Stadler PF. Phylogenetic distribution of plant snoRNA families. BMC Genomics. 17 (2016), 1, 969. dx.doi.org/10.1186/s12864-016-3301-2
Peng L, Yarman A, Jetzschmann KJ, Jeoung JH, Schad D, Dobbek H, Wollenberger U, Scheller FW. Molecularly imprinted electropolymer for a hexameric heme protein with direct electron transfer and peroxide electrocatalysis. Sensors. 16 (2016), 3, Art. 272, 11 S. dx.doi.org/10.3390/s16030272
Pösel C, Möller K, Boltze J, Wagner DC, Weise G. Isolation and flow cytometric analysis of immune cells from the ischemic mouse brain. Journal of visualized experiments : JoVE. 108 (2016), Art. e53658, 8 S. dx.doi.org/10.3791/53658
Prashant P, Elangovan E, Hettrich C, Möller HH, Linker T. Synthesis of 2-Thiocarbohydrates and Their Binding to Concanavalin A. J. Org. Chem. 81 (2016) 8595–8603: DOI dx.doi.org/10.1021/acs.joc.6b00987
Prill S, Bavli D, Levy G, Ezra E, Schmälzlin E, Jaeger MS, Schwarz M, Duschl C, Cohen M, Nahmias Y. Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone. Archives of toxicology. 90 (2016), 5, S. 1181-1191. dx.doi.org/10.1007/s00204-015-1537-2
Prokopović VZ, Vikulina AS, Sustr D, Duschl C, Volodkin D. Biodegradation-resistant multilayers coated with gold Nnnoparticles : toward a tailor-made artificial extracellular matrix. ACS Applied materials and interfaces. 8 (2016), 37, S. 24345 - 24349. dx.doi.org/10.1021/acsami.6b10095
Quast RB, Ballion B, Stech M, Sonnabend A, Varga BR, Wüstenhagen DA, Kele P, Schiller SM, Kubick S. Cell-free synthesis of functional human epidermal growth factor receptor: Investigation of ligand-independent dimerization in Sf21 microsomal membranes using non-canonical amino acids. Sci Rep. 2016 Sep 27;6:34048. DOI dx.doi.org/10.1038/srep34048 Artikel
Quast RB, Sonnabend A, Stech M, Wüstenhagen DA, Kubick S. High-yield cell-free synthesis of human EGFR by IRES-mediated protein translation in a continuous exchange cell-free reaction format. Sci Rep. 2016 Jul 26;6:30399. DOI dx.doi.org/10.1038/srep30399 Artikel
Rekers NV, Bajema IM, Mallat MJ, Petersen B, Anholts JD, Swings GM, van Miert PP, Kerkhoff C, Roth J, Popp D, van Groningen MC, Baeten D, Goemaere N, Kraaij MD, Zandbergen M, Heidt S, van Kooten C, de Fijter JW, Claas FH, Eikmans M. Beneficial immune effects of myeloid-related proteins in kidney transplant rejection. American journal of transplantation. 16 (2016), 5, S. 1441-1455. dx.doi.org/10.1111/ajt.13634
Restrepo G, Stadler PF. Assessing greenness of chemical reactions and synthesis plans through posetic landscapes. ACS sustainable chemistry & engineering. 4 (2016), 4, S. 2191-2199. dx.doi.org/10.1021/acssuschemeng.5b01649
Righetti F, Nuss AM, Twittenhoff C, Beele S, Urban K, Will S, Bernhart SH, Stadler PF, Dersch P, Narberhaus F. Temperature-responsive in vitro RNA structurome of Yersinia pseudotuberculosis. Proceedings of the National Academy of Sciences of the United States of America : PNAS. 113 (2016), 26, S. 7237-7242. dx.doi.org/10.1073/pnas.1523004113
Rohani L, Fabian C, Holland H, Naaldijk Y, Dressel R, Löffler-Wirth H, Binder H, Arnold A, Stolzing A. Generation of human induced pluripotent stem cells using non-synthetic mRNA. Stem cell research. 16 (2016), 3, S. 662-672. dx.doi.org/10.1016/j.scr.2016.03.008
Roshyara NR, Horn K, Kirsten H, Ahnert P, Scholz M. Comparing performance of modern genotype imputation methods in different ethnicities. Scientific Reports. 6 (2016), Art. 34386, 12 S. dx.doi.org/10.1038/srep34386
Sack U, Boldt A, Mallouk N, Gruber R, Krenn V, Berger-Depincé AE, Conrad K, Tarnok A, Lambert C, Reinhold D, Fricke S. Cellular analyses in the monitoring of autoimmune diseases. Autoimmunity reviews. 15 (2016), 9, S. 883-9. dx.doi.org/10.1016/j.autrev.2016.07.010
Sauer M, Altrichter J, Haubner C, Pertschy A, Wild T, Doß F, Mencke T, Thomsen M, Ehler J, Henschel J, Doß S, Koch S, Richter G, Nöldge-Schomburg G, Mitzner SR. Bioartificial therapy of sepsis : Changes of norepinephrine-dosage in patients and influence on dynamic and cell based liver tests during extracorporeal treatments. BioMed research international. (2016), Art. 7056492, 11 S. dx.doi.org/10.1155/2016/7056492
Schnauß J, Händler T, Käs JA. Semiflexible biopolymers in bundled arrangements. Polymers. 8 (2016), 8, Art. 274, 23 S. dx.doi.org/10.3390/polym8080274
Schuldt C, Schnauß J, Händler T, Glaser M, Lorenz J, Golde T, Käs JA, Smith DM. Tuning synthetic semiflexible networks by bending stiffness. Physical review letters. 117 (2016), 19, 5 S. dx.doi.org/10.1103/PhysRevLett.117.197801
Schumacher S, Seitz H. A novel immunoassay for quantitative drug abuse screening in serum. Journal of immunological methods. 436 (2016), S. 34-40. dx.doi.org/10.1016/j.jim.2016.06.004
Schumacher S, Seitz H. Quality control of antibodies for assay development. New Biotechnolog. 33 (2016), 5 Pt A, S. 544-50. dx.doi.org/10.1016/j.nbt.2016.02.001
Skeide MA, Kraft I, Müller B, Schaadt G, Neef NE, Brauer J, Wilcke A, Kirsten H, Boltze J, Friederici AD. NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school. Brain. 139 (2016), 10,S. 2792-2803. dx.doi.org/10.1093/brain/aww153
Sombetzki M, Koslowski N, Doss S, Loebermann M, Trauner M, Reisinger EC, Sauer M. Biosensor for hepatocellular injury corresponds to experimental scoring of hepatosplenic schistosomiasis in mice. BioMed research international. (2016), Art. 1567254, 7 S. dx.doi.org/10.1155/2016/1567254
Sponholz C, Matthes K, Rupp D, Backaus W, Klammt S, Karailieva D, Bauschke A, Settmacher U, Kohl M, Clemens MG, Mitzner S, Bauer M, Kortgen A. Molecular adsorbent recirculating system and single-pass albumin dialysis in liver failure : A prospective, randomised crossover study. Critical care. 20(2016), Art. 2. dx.doi.org/10.1186/s13054-015-1159-3
Su X, Tárnok A. Cytometry advancement: A perspective from China. Cytometry A. 2016, 89 (12), S. 1049-1051. dx.doi.org/10.1002/cyto.a.23036
Tárnok A. Class struggle under the microscope. Cytometry A. 2016, 89 (10), S. 879-880. dx.doi.org/10.1002/cyto.a.23002
Tárnok A. Set Them Free! Cytometry A. 2016, 89 (11), S. 965-966. dx.doi.org/10.1002/cyto.a.23020
Thoring L, Wüstenhagen DA, Borowiak M, Stech M, Sonnabend A, Kubick S. Cell-Free Systems Based on CHO Cell Lysates: Optimization Strategies, Synthesis of »Difficult-to-Express« Proteins and Future Perspectives. PLoS One. 2016 Sep 29;11(9):e0163670. DOI dx.doi.org/10.1371/journal.pone.0163670 Artikel
Tuncel J, Haag S, Hoffmann MH, Yau AC, Hultqvist M, Olofsson P, Bäcklund J, Nandakumar KS, Weidner D, Fischer A, Leichsenring A, Lange F, Haase C, Lu S, Gulko PS, Steiner G, Holmdahl R. Animal models of rheumatoid arthritis (I): Pristane-induced arthritis in the rat. PLoS One. 11 (2016), 5, Art. e0155936, 17 S. dx.doi.org/10.1371/journal.pone.0155936
Uhlig K, Wegener T, He J, Zeiser M, Bookhold J, Dewald I, Godino N, Jaeger M, Hellweg T, Fery A, Duschl C. Patterned thermoresponsive microgel coatings for noninvasive processing of adherent cells. Biomacromolecules. 17 (2016), 3, S. 1110-1116. dx.doi.org/10.1021/acs.biomac.5b01728
Velandia-Huerto CA, Berkemer SJ, Hoffmann A, Retzlaff N, Romero Marroquín LC, Hernández-Rosales M, Stadler PF, Bermúdez-Santana CI. Orthologs, turn-over, and remolding of tRNAs in primates and fruit flies. BMC Genomics. (2016), 17:617. dx.doi.org/10.1186/s12864-016-2927-4
Velandia-Huerto CA, Gittenberger AA, Brown FD, Stadler PF, Bermúdez-Santana CI. Automated detection of ncRNAs in the draft genome sequence of a colonial tunicate: the carpet sea squirt Didemnum vexillum. BMC Genomics. (2016), 17:691. dx.doi.org/10.1186/s12864-016-2934-5
Velk N, Uhlig K, Vikulina A, Duschl C, Volodkin D. Mobility of lysozyme in poly(l-lysine)/hyaluronic acid multilayer films. Colloids and surfaces B. 147 (2016), S. 343-350. dx.doi.org/10.1016/j.colsurfb.2016.07.055
Vikulina AS, Anissimov YG, Singh P, Prokopović VZ, Uhlig K, Jaeger MS, von Klitzing R, Duschl C, Volodkin D. Temperature effect on the build-up of exponentially growing polyelectrolyte multilayers. An exponential-to-linear transition point. Physical chemistry, chemical physics : PCCP. 18 (2016), 11, S. 7866-7874. dx.doi.org/10.1039/c6cp00345a
Wagner L, Björkqvist M, Lundh SH, Wolf R, Börgel A, Schlenzig D, Ludwig HH, Rahfeld JU, Leavitt B, Demuth HU, Petersén Å, von Hörsten S. Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington‘s Disease: increased NPY levels and differential degradation of the NPY1-30 fragment. Journal of neurochemistry. 137 (2016), 5, S. 820-837. dx.doi.org/10.1111/jnc.13624
Wege AK, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, Lehmann J. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. mAbs. 6 (2016), 4, S. 968-977. dx.doi.org/10.4161/mabs.29111
Wilcke A, Müller B, Schaadt G, Friederici A, Emmrich F, Brauer J, Neef N, Skeide MA, Kraft I, Czepezauer I, Bobovnikov N, Kirsten H, Boltze J. High acceptance of an early dyslexia screening test involving genetic analyses in Germany. European journal of human genetics. 24 (2016), 2, S. 178-182. dx.doi.org/10.1038/ejhg.2015.103
Wittke S, Baxmann S, Fahlenkamp D, Schmiedeknecht G, Kebbel K, Kießig ST. Rationales for a multi-epitope approach in an autologous renal cell cancer immunostimulant. Journal of vaccines & vaccination 7 (2016), 4, Art. 327, 5 S. dx.doi.org/10.4172/2157-7560.1000327
Wulff M, Baumann M, Thümmler A, Yadav JK, Heinrich L, Knüpfer U, Schlenzig D, Schierhorn A, Rahfeld JU, Horn U, Balbach J, Demuth HU, Fändrich M. Enhanced fibril fragmentation of n-terminally truncated and pyroglutamyl-modified Aβ peptides. Angewandte Chemie. International edition. 55 (2016), 16, S. 5081-5084. dx.doi.org/10.1002/anie.201511099
Zaitseva E, Rio Martinez J del, Dondapati SK, Baaken G, Petersen S, Kubick S, Behrends JC. hERG ion channel activity measured in planar lipid bilayer arrays: Reconstitution from eukaryotic cell-free expression system and cellular membrane preparations. Biophysical journal. 110 (2016), 3, Supplement 1, S. 446a. dx.doi.org/10.1016/j.bpj.2015.11.2399

Publikationen 2015

Barzon L, Pacenti M, Ulbert S, Palù G. Latest developments and challenges in the diagnosis of human West Nile virus infection. Expert review of anti-infective therapy. 13 (2015), 3, S. 327-42. DOI: dx.doi.org/10.1586/14787210.2015.1007044
Barzon L, Papa A, Lavezzo E, Franchin E, Pacenti M, Sinigaglia A, Masi G, Trevisan M, Squarzon L, Toppo S, Papadopoulou E, Nowotny N, Ulbert S, Piralla A, Rovida F, Baldanti F, Percivalle E, Palù G. Phylogenetic characterization of Central/Southern European lineage 2 West Nile virus: analysis of human outbreaks in Italy and Greece, 2013-2014. Clinical microbiology and infection. 21 (2015), 12, 1122.e1-1122.e10. DOI dx.doi.org/10.1016/j.cmi.2015.07.018
Bechlars S, Jäckel C, Diescher S, Wüstenhagen DA, Kubick S, Dieckmann R, Strauch E. Characterization of trh2 Harbouring Vibrio parahaemolyticus Strains Isolated in Germany. PLOS ONE | DOI: dx.doi.org/10.1371/journal.pone.0118559. Article
Betat H, Mede T, Tretbar S, Steiner L, Stadler PF, Mörl M, Prohaska SJ. The ancestor of modern Holozoa acquired the CCA-adding enzyme from Alphaproteobacteria by horizontal gene transfer. Nucleic acids research. 43 (2015), 14, 6739-46. DOI: dx.doi.org/10.1093/nar/gkv631
Boltze J, Arnold A, Walczak P, Jolkkonen J, Cui L, Wagner DC. The dark side of the force - constraints and complications of cell therapies for stroke. Frontiers in neurology. 6 (2015), 155. DOI dx.doi.org/10.3389/fneur.2015.00155
Bosserdt M, Erdőssy J, Lautner G, Witt J, Köhler K, Gajovic-Eichelmann N, Yarman A, Wittstock G, Scheller FW, Gyurcsányi RE. Microelectrospotting as a new method for electrosynthesis of surface-imprinted polymer microarrays for protein recognition. Biosensors and bioelectronics. 73 (2015), S.123-9. DOI dx.doi.org/10.1016/j.bios.2015.05.049
Brener O, Dunkelmann T, Gremer L, Van Groent T, Mirecka E, Kadishi I, Willuweit A, Kutzsche J, Jürgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J, Oesterhelft F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D. QIAD assay for quantitating a compound‘s efficacy in elimination of toxic Aβ oligomers. Scientific Reports. 5 (2015), 13222. DOI dx.doi.org/10.1038/srep13222
Brödel AK, Wüstenhagen DA, Kubick S. Cell-Free Protein Synthesis Systems Derived from Cultured Mammalian Cells. Methods Mol Biol. 2015;1261:129-40. doi: dx.doi.org/10.1007/978-1-4939-2230-7_7
Buga AM, Scheibe J, Moller K, Ciobanu O, Posel C, Boltze J, Popa-Wagner A. Granulocyte colony-stimulating factor and bone marrow mononuclear cells for stroke treatment in the aged brain. Current neurovascular research. 12 (2015), 2, S. 155-62. DOI dx.doi.org/10.2174/1567202612666150311112550
Burkhardt R, Kirsten H, Beutner F, Holdt LM, Gross A, Teren A, Tönjes A, Becker S, Krohn K, Kovacs P, Stumvoll M, Teupser D, Thiery J, Ceglarek U, Scholz M. Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood. PLoS Genetics. 11 (2015), 9:e1005510. DOI dx.doi.org/10.1371/journal.pgen.1005510
Couturier J-P, Sütterlin M, Laschewsky A, Hettrich C, Wischerhoff E. Inverse Opale aus responsiven Hydrogelen für die Detektion von Makromolekülen. Angew. Chem. 127 (2015) 6741-6745, DOI dx.doi.org/10.1002/ange.201500674
Couturier J-P, Sütterlin M, Laschewsky A, Hettrich C, Wischerhoff E. Responsive Inverse Opal Hydrogels for the Sensing of Macromolecules. Angew. Chem. Int. Ed. 54 (2015) 6641-6644, DOI dx.doi.org/10.1002/anie.201500674
Cui LL, Kerkelä E, Bakreen A, Nitzsche F, Andrzejewska A, Nowakowski A, Janowski M, Walczak P, Boltze J, Lukomska B, Jolkkonen J. The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity. Stem cell research and therapy. 6 (2015), 11. DOI dx.doi.org/10.1186/scrt544
Dammers C, Gremer L, Neudecker P, Demuth HU, Schwarten M, Willbold D. Purification and characterization of recombinant N-Terminally Pyroglutamate-modified Amyloid-β variants and structural analysis by solution NMR spectroscopy. PLoS One. 10 (2015), 10, e0139710. DOI: dx.doi.org/10.1371/journal.pone.0139710
Dammers C, Gremer L, Reiß K, Klein AN, Neudecker P, Hartmann R, Sun N, Demuth HU, Schwarten M, Willbold D. Structural analysis and aggregation propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol. PLoS One. 10 (2015), 11, e0143647. DOI dx.doi.org/10.1371/journal.pone.0143647
Ehler J, Koball S, Sauer M, Mitzner S, Hickstein H, Benecke R, Zettl UK. Response to Therapeutic Plasma Exchange as a Rescue Treatment in Clinically Isolated Syndromes and Acute Worsening of Multiple Sclerosis: A Retrospective Analysis of 90 Patients. Plos One 2015 Aug 5;10(8):e0134583. DOI dx.doi.org/10.1371/journal.pone.0134583. eCollection 2015
Eisold U, Sellrie F, Schenk JA, Lenz C, Stöcklein WFM, Kumke MU. Bright or dark immune complexes of anti-TAMRA antibodies for tailored fluorescence-based bioanalysis. Analytical and bioanalytical chemistry. 407 (2015), 12, S. 3313-23. DOI dx.doi.org/10.1007/s00216-015-8538-0
Engelhardt J, Stadler PF. Evolution of the unspliced transcriptome. BMC Evol Biol. 15 (2015), Aug 20, 166.
Fernández AF, Bayón GF, Urdinguio RG, Toraño EG, García MG, Carella A, Petrus-Reurer S, Ferrero C, Martinez-Camblor P, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Bueno C, Menéndez P, Mentink A, Mareschi K, Fabian C, Fagnani C, Medda E, Toccaceli V, Brescianini S, Moran S, Esteller M, Stolzing A, de Boer J, Nisticò L, Stazi MA, Fraga MF. H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells. Genome Research. 2015 Jan;25(1):27-40. DOI dx.doi.org/10.1101/gr.169011.113
Feoktistova N, Stoychev G, Puretskiy N, Ionov L, Volodkin D. Porous thermo-responsive pNIPAM microgels. European polymer journal. 68 (2015), S. 65-656. DOI dx.doi.org/10.1016/j.eurpolymj.2015.03.040
Fischer D, Angenvoort J, Ziegler U, Fast C, Maier K, Chabierski S, Eiden M, Ulbert S, Groschup MH, Lierz M. DNA vaccines encoding the envelope protein of West Nile virus lineages 1 or 2 administered intramuscularly, via electroporation and with recombinant virus protein induce partial protection in large falcons (Falco spp.). Vet Res. 2015 Aug 17;46(1):87. DOI dx.doi.org/10.1186/s13567-015-0220-1
Fjeld K, Weiss FU, Lasher D, Rosendahl J, Chen JM, Johansson BB, Kirsten H, Ruffert C, Masson E, Steine SJ, Bugert P, Cnop M, Grützmann R, Mayerle J, Mössner J, Ringdal M, Schulz HU, Sendler M, Simon P, Sztromwasser P, Torsvik J, Scholz M, Tjora E, Férec C, Witt H, Lerch MM, Njølstad PR, Johansson S, Molven A. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Nature genetics. 47 (2015), 5, S. 518-22. DOI dx.doi.org/10.1038/ng.3249
Gardner PP, Fasold M, Burge SW, Ninova M, Hertel J, Kehr S, Steeves TE, Griffiths-Jones S, Stadler PF. Conservation and losses of non-coding RNAs in avian genomes. PLoS One. 10 (2015), 3, e0121797. DOI dx.doi.org/10.1371/journal.pone.0121797
Gärtig C, Niemann K, Berthold J, Giel L, Leitschuh N, Boehm C, Roussak L, Vetter K, Kuhlmeier D. Development of a point-of-care-device for fast detection of periodontal pathogens. BMC Oral Health. 2015 Dec 24;15(1):165.
Georgi V, Georgi L, Blechert M, Bergmeister M, Zwanzig M, Wüstenhagen DA, Bier FF, Junga E, Kubick S. On-chip automation of cell-free protein synthesis: new opportunities due to a novel reaction mode. Lab Chip, 2015 Nov 11. [Epub ahead of print] DOI dx.doi.org/10.1039/C5LC00700C Article
Giri P, Ebert S, Braumann UD, Kremer M, Giri S, Machens HG, Bader A. Skin regeneration in deep second-degree scald injuries either by infusion pumping or topical application of recombinant human erythropoietin gel. Drug design, development and therapy. 9 (2015), S. 2565-2579. DOI dx.doi.org/10.2147/DDDT.S79425
Godino N, Jorde F, Lawlor D, Jaeger MS, Duschl C. Purification of microalgae from bacterial contamination using a disposable inertia-based microfluidic device. Journal of Micromechanics and Microengineering, 25 (2015), 8, 084002. DOI dx.doi.org/10.1088/0960-1317/25/8/084002
Grunwald T, Ulbert S. Improvement of DNA vaccination by adjuvants and sophisticated delivery devices: vaccine-platforms for the battle against infectious diseases. Clin Exp Vaccine Res. 2015 Jan;4(1):1-10. DOI dx.doi.org/10.7774/cevr.2015.4.1.1
Hahn M B, Solomun T, Wellhausen R, Herrmann S, Seitz H, Meyer S, Kunte H-J, Zeman J, Uhlig F, Smiatek J, Sturm H. The influence of the compatible solute ectoine on the local water structure: implications for the binding of the protein G5P to DNA. The Journal of Physical Chemistry, B, 119 (2015) 49, S. 15212–15220. DOI dx.doi.org/10.1021/acs.jpcb.5b09506
Haid S, Grethe C, Bankwitz D, Grunwald T, Pietschmann T. Identification of a human respiratory syncytial virus (hRSV) cell entry inhibitor by using a novel lentiviral pseudotype (hRSVpp) system. Journal of virology. 2015 Dec 30. [Epub ahead of print] DOI dx.doi.org/10.1128/JVI.03074-15
Hartlage-Rübsamen M, Waniek A, Meissner J, Morawski M, Schilling S, Jäger C, Kleinschmidt M, Cynis H, Kehlen A, Arendt T, Demuth HU, Rossner S. Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease. Acta Neuropathologica 2015; 129(4): 565-583. DOI dx.doi.org/10.1007/s00401-015-1395-2
Heathman TR, Stolzing A, Fabian C, Rafiq QA, Coopman K, Nienow AW, Kara B, Hewitt CJ. Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production. Cytotherapy. 17 (2015), 11, S. 1524-35. DOI dx.doi.org/10.1016/j.jcyt.2015.08.002
Hellmuth M, Wieseke N, Lechner M, Lenhof HP, Middendorf M, Stadler PF. Phylogenomics with paralogs. Proceedings of the National Academy of Sciences of the United States of America. 112 (2015), 7, 2058-63. DOI dx.doi.org/10.1073/pnas.1412770112
Hertel J, Stadler PF. The expansion of animal MicroRNA families revisited. Life (Basel). 5 (2015), 1, 905-20. DOI dx.doi.org/10.3390/life5010905
Hoffmann S, Stadler PF, Strimmer K. A simple data-adaptive probabilistic variant calling model. Algorithms for molecular biology. 10 ( 2015), 10. DOI dx.doi.org/10.1186/s13015-015-0037-5
Höner Zu Siederdissen C, Hofacker IL, Stadler PF. Product Grammars for Alignment and Folding. IEEE/ACM Trans Comput Biol Bioinform. 12 (2015), 3, 507-19.
Hüttl C, Hettrich C, Riedel M, Henklein P, Rawel H, Bier FF. Development of peptidyl lysine dendrons: 1,3-Dipolar cycloaddition for peptide coupling and antibody recognition. Chemical biology and drug design. 85 (2015), 5, S. 565-573. DOI dx.doi.org/10.1111/cbdd.12444
Janowski M, Wagner DC, Boltze J. Stem cell-based tissue replacement after stroke: factual necessity or notorious fiction? Stroke. 46 (2015), 8, S. 2354-63. DOI dx.doi.org/10.1161/STROKEAHA.114.007803
Jeenduang N, Porntadavity S, von Nickisch-Rosenegk M, Bier FF, Promptmas C. Two-dye based arrayed primer extension for simultaneous multigene detection in lipid metabolism. Clinica chimica acta. 442 (2015), S. 36-43. DOI dx.doi.org/10.1016/j.cca.2015.01.005
Jetzschmann KJ, Jágerszki G, Dechtrirat D, Yarman A, Gajovic-Eichelmann N, Gilsing HD, Schulz B, Gyurcsányi RE, Scheller FW. Vectorially imprinted hybrid nanofilm for Acetylcholinesterase recognition. Advanced functional materials. 25 (2015), 32, S. 5178-5183. DOI dx.doi.org/10.1002/adfm.201501900
Kee NLA, Krause J, Blatch GL, Muramoto K, Sakka K, Sakka M, Naudé RJ, Wagner L, Wolf R, Rahfeld JU, Demuth HU, Mielicki WP, Frost CL. The proteolytic profile of human cancer procoagulant suggests that it promotes cancer metastasis at the level of activation rather than degradation. Protein Journal. 34 (2015), 5, S. 338-48. DOI dx.doi.org/10.1007/s10930-015-9628-8
Kim H, Won SJ, Fabian C, Kang M, Szardenings M, Shin M. Mitochondrial DNA aberrations and pathophysiological implications in hematopoietic diseases, chronic inflammatory diseases, and cancers. Annals of Laboratory Medicine. 2015 Jan;35(1):1-14. DOI dx.doi.org/10.3343/alm.2015.35.1.1
Kim JE, Phan TX, Nguyen VH, Dinh-Vu HV, Zheng JH, Yun M, Park SG, Hong Y, Choy HE, Szardenings M, Hwang W, Park JA,Park S, Im SH, Min JJ. Salmonella typhimurium suppresses tumor growth via the pro-inflammatory Cytokine Interleukin-1β. Theranostics. 5 (2015), 12, S. 1328-42. DOI dx.doi.org/10.7150/thno.11432
Kirsten H, Al-Hasani H, Holdt L, Gross A, Beutner F, Krohn K, Horn K, Ahnert P, Burkhardt R, Reiche K, Hackermüller J, Löffler M, Teupser D, Thiery J, Scholz M. Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci. Hum Mol Genet. 2015 May 27.
Kleinschmidt M, Schoenfeld R, Göttlich C, Bittner D, Metzner JE, Leplow B, Demuth HU. Characterizing aging, mild cognitive Impairment, and Dementia with blood-based biomarkers and neuropsychology. Journal of Alzheimer‘s Disease. 50 (2015), 1, S. 111-26. DOI dx.doi.org/10.3233/JAD-143189
Köberle M, Müller K, Kamprad M, Horn F, Scholz M. Monitoring disease progression and therapeutic response in a disseminated tumor model for Non-Hodgkin Lymphoma by bioluminescence imaging. Molecular Imaging. 14 (2015), 400-13.
Kraft I, Cafiero R, Schaadt G, Brauer J, Neef NE, Müller B, Kirsten H, Wilcke A, Boltze J, Friederici AD, Skeide MA. Cortical differences in preliterate children at familiar risk of dyslexia are similar to those observed in dyslexic readers. Brain. 138 (2015), (Pt 9):e378. DOI dx.doi.org/10.1093/brain/awv036
Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Bergmann AK, Betts MJ, Carrillo-de-Santa-Pau E, Doose G, Gutwein J, Richter J, Hovestadt V, Huang B, Rico D, Jühling F, Kolarova J, Lu Q, Otto C, Wagener R, Arnolds J, Burkhardt B, Claviez A, Drexler HG, Eberth S, Eils R, Flicek P, Haas S, Hummel M, Karsch D, Kerstens HH, Klapper W, Kreuz M, Lawerenz C, Lenze D, Loeffler M, López C, MacLeod RA, Martens JH, Kulis M, Martín-Subero JI, Möller P, Nagel I, Picelli S, Vater I, Rohde M, Rosenstiel P, Rosolowski M, Russell RB, Schilhabel M, Schlesner M, Stadler PF, Szczepanowski M, Trümper L, Stunnenberg HG; ICGC MMML-Seq project; BLUEPRINT project, Küppers R, Ammerpohl O, Lichter P, Siebert R, Hoffmann S, Radlwimmer B. DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control. Nature Genetics. 47 (2015), 11, 1316-25. DOI dx.doi.org/10.1038/ng.3413
Laubichler MD, Stadler PF, Prohaska SJ, Nowick K. The relativity of biological function. Theory Biosciences. 134 (2015), 3-4, 143-7. DOI dx.doi.org/10.1007/s12064-015-0215-5
Lauster D, Pawolski D, Storm J, Ludwig K, Volkmer R, Memczak H, Herrmann A, Bhatia S. Potential of acylated peptides to target the influenza A virus. Beilstein journal of organic chemistry. 11 (2015), S. 589-595. DOI dx.doi.org/10.3762/bjoc.11.65
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Lehmann J, Schulz RM, Sanzenbacher R. Strategische Betrachtungen zur Konzeption und Wahl von Tiermodellen bei nicht-klinischen Prüfungen von zellbasierten Therapeutika. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2015 Oct 2. [Epub ahead of print] DOI dx.doi.org/10.1007/s00103-015-2239-x
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Lim JS, Nguyen KC, Han JM, Jang IS, Fabian C, Cho KA. Direct regulation of TLR5 expression by Caveolin-1. Molecules and cells. 38 (2015), 12, S. 1111-7. DOI dx.doi.org/10.14348/molcells.2015.0213
Lim JS, Nguyen KC, Nguyen CT, Jang IS, Han JM, Fabian C, Lee SE, Rhee JH, Cho KA. Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence. Aging Cell. 14 (2015), 5, S. 907-15. DOI dx.doi.org/10.1111/acel.12383
Liu B, Rahfeld JU, Kleinschmidt M, O‘Nuallain B, Le K, Lues I, Caldarone BJ, Schilling S, Demuth HU, Lemere CA. An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice. Neubiology of Aging. 36 (2015), 12, S. 3187–3199. DOI dx.doi.org/10.1016/j.neurobiolaging.2015.08.021
Liu X, Hinney A, Scholz M, Scherag A, Tönjes A, Stumvoll M, Stadler PF, Hebebrand J, Böttcher Y. Indications for potential parent-of-origin effects within the FTO gene. PLoS One. 10 (2015), 3, e0119206. DOI dx.doi.org/10.1371/journal.pone.0119206
Männel C, Meyer L, Wilcke A, Boltze J, Kirsten H, Friederici AD. Working-memory endophenotype and dyslexia-associated genetic variant predict dyslexia phenotype. Cortex. 71 (2015), S. 291-305. DOI dx.doi.org/10.1016/j.cortex.2015.06.029
Maruschke M, Riebold D, Holtfreter MC, Sombetzki M, Mitzner S, Loebermann M, Reisinger EC, Hakenberg OW. Pneumocystis pneumonia (PCP) and Pneumocystis jirovecii carriage in renal transplantation patients: a single-centre experience. Wien Klin Wochenschr. 2014 Dec;126(23-24):762-6.
Möller K, Pösel C, Kranz A, Schulz I, Scheibe J, Didwischus N, Boltze J, Weise G, Wagner DC. Arterial hypertension aggravates innate immune responses after experimental stroke. Frontiers in cellular neuroscience. 9 (2015), 461. DOI dx.doi.org/10.3389/fncel.2015.00461
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Müller S, Schubert A, Zajac J, Dyck T, Oelkrug C. IgY anti-bodies in human nutrition for disease prevention. Nutrition Journal. 14 (20159, 109. DOI dx.doi.org/10.1186/s12937-015-0067-3
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Nitsche A, Rose D, Fasold M, Reiche K, Stadler PF. Comparison of splice sites reveals that long noncoding RNAs are evolutionarily well conserved. RNA. 2015 May;21(5):801-12.
Nitzsche B, Frey S, Collins LD, Seeger J, Lobsien D, Dreyer A, Kirsten H, Stoffel MH, Fonov VS, Boltze J. A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes. Front in neuroanatomy. 9 (2015), 69. DOI dx.doi.org/10.3389/fnana.2015.00069
Oelkrug C, Hartke M, Schubert A. Mode of action of anticancer peptides (ACPs) from amphibian origin. Anticancer research. 35 (2015), 2, S. 635-43.
Oelkrug C, Horn K, Makert GR, Schubert A. Novel in vitro platform to investigate myotube atrophy. Anticancer research. 35 (2015), 4, S. 2085-91.
Oelkrug C, Sack U, Boldt A, Nascimento IC, Ulrich H, Fricke S. Antibody- and aptamer-strategies for GvHD prevention. Journal of Cellular and Molecular Medicine. 2015 Jan;19(1):11-20. DOI: dx.doi.org/10.1111/jcmm.12416
Prill S, Bavli D, Levy G, Ezra E, Schmälzlin E, Jaeger MS, Schwarz M, Duschl C, Cohen M, Nahmias Y. Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone. Archive of toxicology. 2015 Jun 4. [Epub ahead of print] DOI dx.doi.org/10.1007/s00204-015-1537-2
Prokopovic V, Duschl C, Volodkin D. Hyaluronic Acid/Poly-l-Lysine Multilayers as Reservoirs for Storage and Release of Small Charged Molecules. Macromolecular Bioscience. 15 (2015), 10, S. 1357-1363. DOI dx.doi.org/10.1002/mabi.201500093
Quast RB, Mrusek D, Hoffmeister C, Sonnabend A, Kubick S. Cotranslational incorporation of non-standard amino acids using cell-free protein synthesis. FEBS Lett. 2015 Jul 8;589(15):1703-12. doi: dx.doi.org/10.1016/j.febslet.2015.04.041. Epub 2015 May 1. Article
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Rizzoli A, Jimenez-Clavero MA, Barzon L, Cordioli P, Figuerola J, Koraka P, Martina B, Moreno A, Nowotny N, Pardigon N, Sanders N, Ulbert S, Tenorio A. The challenge of West Nile virus in Europe: knowledge gaps and research priorities. Eurosurveillance. 20 (2015), 20, 5. DOI dx.doi.org/10.2807/1560-7917.ES2015.20.20.21135
Riemschneider S, Herzberg M, Lehmann J. Subtoxic Doses of Cadmium Modulate Inflammatory Properties of Murine RAW 264.7 Macrophages. Biomed Res Int. 2015;2015:295303. DOI: dx.doi.org/10.1155/2015/295303
Rockstroh A, Barzon L, Pacenti M, Palù G, Niedrig M, Ulbert S. Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections. PLoS neglected tropical diseases. 9 (2015), 11 :e0004218. DOI http://dx.doi.org/10.1371/journal.pntd.0004218
Sahyoun AH, Hölzer M, Jühling F, Höner zu Siederdissen C, Al-Arab M, Tout K, Marz M, Middendorf M, Stadler PF, Bernt M. Towards a comprehensive picture of alloacceptor tRNA remolding in metazoan mitochondrial genomes. Nucleic acids research. 43 (2015), 16, 8044-56. DOI dx.doi.org/10.1093/nar/gkv746
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Schlenzig D, Wermann M, Ramsbeck D, Moenke-Wedler T, Schilling S. Expression, purification and initial characterization of human meprin β from Pichia pastoris. Protein expression and purification. 116 (2015), S. 75-81. DOI dx.doi.org/10.1016/j.pep.2015.08.001
Schmiedeknecht G. Challenges of Manufacturing of ATMP’s for clinical trials. 2015 PDA Europe Conference Advanced Therapy Medicinal Products, Amsterdam, Netherlands, June 2–3, 2015.
Schmidt F, Hilger N, Oelkrug C, Svanidze E, Ruschpler P, Eichler W, Boldt A, Emmrich F, Fricke S. Flow cytometric analysis of the graft-versus-Leukemia-effect after hematopoietic stem cell transplantation in mice. Cytometry A. 87 (2015), 4, S. 334-45. DOI dx.doi.org/10.1002/cyto.a.22619
Schumacher S, Muekusch S, Seitz H. Up-to-date applications of microarrays and their way to commercialization. Microarrays. 4 (2015), 2, S. 196-213. DOI dx.doi.org/10.3390/microarrays4020196
Schumacher S, Seitz H. Multiplex approach for an immunological detection of drugbase: a validation study. Toxichem Krimtech. 39 (2015), 82, S. 151-154.
Seifert F, Demuth HU, Weichler T, Ludwig HH, Tittmann K, Schilling S. Phosphate ions and glutaminyl cyclases catalyze the cyclization of glutaminyl residues by facilitating synchronized proton transfers. Bioorganic chemistry. 60 (2015), S. 98-101. DOI http://dx.doi.org/10.1016/j.bioorg.2015.04.005
Sergeeva A, Feoktistova N, Prokopovic V, Gorin D, Volodkin D. Design of Porous Alginate Hydrogels by Sacrificial CaCO3 Templates: Pore Formation Mechanism. Advanced material interfaces. 2 (2015), 18, 1500386. DOI http://dx.doi.org/10.1002/admi.201500386
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Sergeeva A, Volkova EK, Bratashov DN, Shishkin MI, Atkin VS, Markin VS, Skaptsov AA, Volodkin D, Gorin DA. Layer-by-layer assembled highly absorbing hundred-layer films containing a phthalocyanine dye: Fabrication and photosensibilization by thermal treatment. Thin solid films. 583 (2015), S. 60-69. DOI dx.doi.org/10.1016/j.tsf.2015.03.050
Sergeeva AS, Gorin DA, Volodkin DV. In-situ assembly of Ca-alginate gels with controlled pore loading / release capability. Langmuir. 31 (2015), 39, S. 10813-21. DOI dx.doi.org/10.1021/acs.langmuir.5b01529
Skeide MA, Kirsten H, Kraft I, Schaadt G, Müller B, Neef N, Brauer J, Wilcke A, Emmrich F, Boltze J, Friederici AD. Genetic dyslexia risk variant is related to neural connectivity patterns underlying phonological awareness in children. Neuroimage. 118 (2015), S. 414-21. DOI dx.doi.org/10.1016/j.neuroimage.2015.06.024
Stech M, Kubick K. Cell-Free Synthesis Meets Antibody Production: A Review. Antibodies 2015, 4, 12-33; DOI: dx.doi.org/10.3390/antib4010012.
Stetciura IY, Yashchenok A, Masic A, Lyubin EV, Inozemtseva OA, Drozdova MG, Markvichova EA, Khlebtsov BN, Fedyanin AA, Sukhorukov GB, Gorin DA, Volodkin D. Composite SERS-based satellites navigated by optical tweezers for single cell analysis. Analyst. 140 (2015), 15, S. 4981-6. DOI dx.doi.org/10.1039/c5an00392j
Sustr D,Velk N, Duschl C, Volodkin DV. A FRAP-based evaluation of protein diffusion in polyelectrolyte multilayers. European Polymer Journal. 68 (2015), S. 665-670. DOI dx.doi.org/10.1016/j.eurpolymj.2015.03.063
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Tröger V, Niemann K, Gärtig C, Kuhlmeier D. Isothermal Amplification and Quantification of Nucleic Acids and its Use in Microsystems. Journal of Nanomedicine & Nanotechnology. 01/2015; 6(3). DOI dx.doi.org/10.4172/2157-7439.1000282
Uyen Nguyen Hoang Phuong, Nenad Gajovic-Eichelmann, Frank. F. Bier, Thanh Ngo Vo Ke. A novel method of immobilizing antigens on gold electrode for immunosensing. Communications in Physics (2015), 25, S. 173-182. DOI dx.doi.org/10.15625/0868-3166/25/2/6239
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Publikationen 2014

Arnold C, Externbrink F, Hackermüller J, Reiche K. CEMDesigner: Design of custom expression microarrays in the post-ENCODE Era. Journal of Biotechnology. 2014 Nov 10;189:154-6. DOI dx.doi.org/10.1016/j.jbiotec.2014.09.012.
Backofen R, Amman F, Costa F, Findeiß S, Richter AS, Stadler PF. Bioinformatics of prokaryotic RNAs. RNA Biology. 2014 May;11(5):470-83. DOI dx.doi.org/10.4161/rna.28647
Balseanu AT, Buga AM, Catalin B, Wagner DC, Boltze J, Zagrean AM, Reymann K, Schaebitz W, Popa-Wagner A. Multimodal approaches for regenerative stroke therapies: combination of granulocyte colony-stimulating factor with bone marrow mesenchymal stem cells is not superior to G-CSF alone. Frontiers in Aging Neuroscience. 2014 Jun 23;6:130.DOI dx.doi.org/10.3389/fnagi.2014.00130.
Barzon L, Pacenti M, Franchin E, Squarzon L, Sinigaglia A, Ulbert S, Cusinato R, Palù G. Isolation of West Nile virus from urine samples of patients with acute infection. Journal of Clinical Microbiology. 214 Sep;52(9):3411-3. DOI dx.doi.org/10.1128/JCM.01328-14.
Boldt A, Borte S, Fricke S, Kentouche K, Emmrich F, Borte M, Kahlenberg F, Sack U. Eight-color immunophenotyping of T-, B-, and NK-cell subpopulations for characterization of chronic immunodeficiencies. Cytometry B Clinical Cytometry. 2014 May;86(3):191-206.DOI: dx.doi.org/10.1002/cyto.b.21162.
Boldt A, Kahlenberg F, Fricke S, Rasche FM, Sack U. Flow cytometric phenotyping of lymphocytes in patients with systemic lupus erythematosus. Cytometry A. 2014 Jul;85(7):567-9.DOI: dx.doi.org/10.1002/cyto.a.22477
Boldt A, Kentouche K, Fricke S, Borte S, Kahlenberg F, Sack U. Differences in FOXP3 and CD127 expression in Treg-like cells in patients with IPEX syndrome. Clinical Immunoloy. 2014 Jul;153(1):109-11. DOI: dx.doi.org/10.1016/j.clim.2014.04.001
Boltze J, Ayata C, Wagner DC, Plesnila N. Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines. Stroke. 2014 Feb;45(2):357. DOI dx.doi.org/10.1161/STROKEAHA.113.004148
Boltze J, Lukomska B, Jolkkonen J; MEMS–IRBI consortium. Mesenchymal stromal cells in stroke: improvement of motor recovery or functional compensation? Journal of Cerebral Blood Flow and Metabolism. 2014 Aug;34(8):1420-1. DOI dx.doi.org/10.1038/jcbfm.2014.94
Burkhardt J, Blume M, Petit-Teixeira E, Hugo Teixeira V, Steiner A, Quente E, Wolfram G, Scholz M, Pierlot C, Migliorini P, Bombardieri S, Balsa A, Westhovens R, Barrera P, Radstake TR, Alves H, Bardin T, Prum B, Emmrich F, Cornelis F, Ahnert P, Kirsten H. Cellular adhesion gene SELP is associated with rheumatoid arthritis and displays differential allelic expression. PLoS One. 2014 Aug 22;9(8):e103872. DOI dx.doi.org/10.1371/journal.pone.0103872
Chabierski S, Barzon L, Papa A, Niedrig M, Bramson JL, Richner JM, Palù G, Diamond MS, Ulbert S. Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop. BMC Infectious Diseases. 2014 May 9;14:246. DOI dx.doi.org/10.1186/1471-2334-14-246
Cynis H, Funkelstein L, Toneff T, Mosier C, Ziegler M, Koch B, Demuth HU, Hook V. Pyroglutamate-Amyloid-? and Glutaminyl Cyclase Are Colocalized with Amyloid-? in Secretory Vesicles and Undergo Activity-Dependent, Regulated Secretion. Neurodegenerative Diseases. 2014; 14(2):85-97. DOI dx.doi.org/10.1159/000358430
Danckert L, Hoppe S, Bier FF, von Nickisch-Rosenegk M. Rapid identification of novel antigens of Salmonella Enteritidis by microarray-based immunoscreening. Microchimica Acta 02/2014; • 3.43 Impact Factor.
Danielyan L, Beer-Hammer S, Stolzing A, Schäfer R, Siegel G, Fabian C, Kahle P, Biedermann T, Lourhmati A, Buadze M, Novakovic A, Proksch B, Gleiter CH, Frey WH, Schwab M. Intranasal delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer‘s and Parkinson‘s disease. Cell Transplantation. 2014;23 Suppl 1:123-39. DOI dx.doi.org/10.3727/096368914X684970
Dechtrirat D, Gajovic-Eichelmann N, Bier FF, Scheller FW. Hybrid Material for Protein Sensing Based on Electrosynthesized MIP on a Mannose Terminated Self-Assembled Monolayer. Adv Func Mater, 24 (2014): 2233-2239.
Dechtrirat D, Gajovic-Eichelmann N, Wojcik F, Hartmann L, Bier FF, Scheller FW. Electrochemical displacement sensor based on ferrocene boronic acid tracer and immobilized glycan for saccharide binding proteins and E. Coli. Biosens Bioelectron. 58 (2014): 1-8.
De Filette M, Chabierski S, Andries O, Ulbert S, Sanders NN. T cell epitope mapping of the e-protein of west nile virus in BALB/c mice. PLoS One. 2014 Dec 15;9(12):e115343.DOI: dx.doi.org/10.1371/journal.pone.0115343
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Wagner DC, Pösel C, Schulz I, Schicht G, Boltze J, Lange F, Scheibe J, Möller K, Weise G. Allometric dose retranslation unveiled substantial immunological side effects of granulocyte colony-stimulating factor after stroke. Stroke. 2014 Feb;45(2):623-6. DOI dx.doi.org/10.1161/STROKEAHA.113.003812
Wege AK, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, Lehmann J. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. mAbs. 2014 Jul-Aug;6(4):968-77. DOI dx.doi.org/10.4161/mabs.29111
Weiler G, Schröder C, Schera F, Dobkowicz M, Kiefer S, Heidtke K R, Hänold S, Nwankwo I, Forgo N, Stanulla M, Eckert C, Graf N. p-BioSPRE – an information and communication technology framework for transnational biomaterial sharing and access. ecancer medical science 2014(8).
Weis S, Schlaich TC, Dehghani F, Carvalho T, Sommerer I, Fricke S, Kahlenberg F, Mössner J, Hoffmeister A. p8 Deficiency causes siderosis in spleens and lymphocyte apoptosis in acute pancreatitis. Pancreas. 2014 Nov;43(8):1277-85. DOI: dx.doi.org/10.1097/MPA.0000000000000172
Weise G, Lorenz M, Pösel C, Maria Riegelsberger U, Störbeck V, Kamprad M, Kranz A, Wagner DC, Boltze J. Transplantation of cryopreserved human umbilical cord blood mononuclear cells does not induce sustained recovery after experimental stroke in spontaneously hypertensive rats. Journal of Cerebral Blood Flow and Metabolism. 2014 Jan;34(1):e1-9. DOI dx.doi.org/10.1038/jcbfm.2013.185
Verstrepen BE, Fagrouch Z, van Heteren M, Buitendijk H, Haaksma T, Beenhakker N, Palù G, Richner JM, Diamond MS, Bogers WM, Barzon L, Chabierski S, Ulbert S, Kondova I, Verschoor EJ. Experimental infection of rhesus macaques and common marmosets with a European strain of west nile virus. PLoS Negl Trop Dis. 2014 Apr 17;8(4):e279.
Xu LX, Holland H, Kirsten H, Ahnert P, Krupp W, Bauer M, Schober R, Mueller W, Fritzsch D, Meixensberger J, Koschny R. Three gangliogliomas: Results of GTG-banding, SKY, genome-wide high resolution SNP-array, gene expression and review of the literature. Neuropathology. 2014 Nov 6. DOI dx.doi.org/10.1111/neup.12176
Zoldan K, Moellmer T, Schneider J, Fueldner C, Knauer J, Lehmann J. Increase of CD25 expression on bovine neutrophils correlates with disease severity in post-partum and early lactating dairy cows. Developmental and comparative immunology. 2014 Dec; 47(2):254-63. DOI: dx.doi.org/10.1016/j.dci.2014.08.002

Publikationen 2013

Arnold C, Stadler PF, Prohaska SJ. Chromatin computation: Epigenetic inheritance as a pattern reconstruction problem. Journal of theoretical biology 336 (2013), S. 61–74. DOI dx.doi.org/10.1016/j.jtbi.2013.07.012
Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, Saliba F, Sauerbruch T, Klammt S, Ockenga J, Pares A, Wendon J, Brünnler T, Kramer L, Mathurin P, de la Mata M, Gasbarrini A, Müllhaupt B, Wilmer A, Laleman W, Eefsen M, Sen S, Zipprich A, Tenorio T, Pavesi M, Schmidt HH, Mitzner S, Williams R, Arroyo V; RELIEF study group. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial. Hepatology. 57(2013), 3, S. 1153–62. DOI dx.doi.org/10.1002/hep.26185
Becker A, Kohlmann S, Alexandru A, Jagla W, Canneva F, Bäuscher C, Cynis H, Sedlmeier R, Graubner S, Schilling S, Demuth HU, von Hörsten S. Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration. BMC Neurosci. 2013 Oct 1;14:108. DOI dx.doi.org/10.1186/1471-2202-14-108
Bernt M, Bleidorn C, Braband A, Dambach J, Donath A, Fritzsch G, Golombek A, Hadrys H, Jühling F, Meusemann K, Middendorf M, Misof B, Perseke M, Podsiadlowski L, Reumont B von, Schierwater B, Schlegel M, Schrödl M, Simon S, Stadler PF, Stöger I, Struck TH. A comprehensive analysis of bilaterian mitochondrial genomes and phylogeny. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 352–364. DOI dx.doi.org/10.1016/j.ympev.2013.05.002
Bernt M, Braband A, Middendorf M, Misof B, Rota-Stabelli O, Stadler PF. Bioinformatics methods for the comparative analysis of metazoan mito-chondrial genome sequences. Molecular phylogenetics and evolution 69 (2013), 2, S. 320–327. DOI dx.doi.org/10.1016/j.ympev.2012.09.019
Bernt M, Braband A, Schierwater B, Stadler PF. Genetic aspects of mitochondrial genome evolution. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 328–338. DOI dx.doi.org/10.1016/j.ympev.2012.10.020
Bernt M, Donath A, Jühling F, Externbrink F, Florentz C, Fritzsch G, Pütz J, Middendorf M, Stadler PF. MITOS: improved de novo metazoan mitochondrial genome annotation. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 313–319. DOI dx.doi.org/10.1016/j.ympev.2012.08.023
Biadglegne F, Tesfaye W, Anagaw B, Tessema B, Debebe T, Anagaw B, Mulu A, Sack U, Rodloff A.C. Tuberculosis lymphadenitis in Ethiopia. Japanese journal of infectious diseases : JJID 66 (2013), 4, S. 263–268.
Blumert C, Kalkhof S, Broche-Heidrich K, Kohajda T, von Bergen M, Horn F. Analysis of the STAT3 intercatome using in-situ biotinylation and SILAC. Journal of Proteomics. 94 (2013), S. 370–386. DOI dx.doi.org/10.1016/j.jprot.2013.08.021
Bodammer P, Kerkhoff C, Maletzki C, Lamprecht G. Bovine colostrum increases pore-forming claudin-2 protein expression but paradoxically not ion permeability possibly by a change of the intestinal cytokine milieu. PLoS One. 8 (2013), 5, e64210. DOI dx.doi.org/10.1371/journal.pone.0064210
Bodammer P, Zirzow E, Klammt S, Maletzki C, Kerkhoff C. Alteration of DSS-mediated immune cell redistribution in murine colitis by oral colostral immunoglobulin. BMC immunology. 14 (2013), e10. DOI dx.doi.org/10.1186/1471-2172-14-10
Boll K, Reiche K, Kasack K, Mörbt N, Kretzschmar AK, Tomm JM, Verhaegh G, Schalken J, von Bergen M, Horn F, Hackermüller J. MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma. Oncogene. 32 (2013), S. 277–285. DOI dx.doi.org/10.1038/onc.2012.55
Breitrück A, Sparmann G, Mitzner S, Kerkhoff C. Establishment of a novel extracorporeal bowel model to study luminal approaches to treat inflammatory bowel disease. Disease Models and Mechanisms. 6 (2013), 6, S. 1487–93. DOI dx.doi.org/10.1242/dmm.011734
Chabierski S, Makert GR, Kerzhner A, Barzon L, Fiebig P, Liebert UG, Papa A, Richner JM, Niedrig M, Diamond MS, Palù G, Ulbert S. Antibody responses in humans infected with newly emerging strains of West Nile Virus in Europe. PLoS One. 8 (2013), 6, e66507. DOI dx.doi.org/10.1371/journal.pone.0066507
Cynis H, Kehlen A, Haegele M, Hoffmann T, Heiser U, Fujii M, Shibazaki Y, Yoneyama H, Schilling S, Demuth HU. Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice. Int J Exp Pathol. 2013 Jun; 94(3):217–25. DOI dx.doi.org/10.1111/iep.12020 Epub 2013 Apr 8.
Dieterich C, Stadler PF. Computational biology of RNA interactions. Wiley interdisciplinary reviews. RNA. Online resource 4 (2013), Nr. 1, S. 107–120. DOI dx.doi.org/10.1002/wrna.1147
Dirnagl, U, Hakim A, MacLeod M, Fisher M, Howells D, Alan SM, Steinberg G, Planas A, Boltze J, Savitz S, Iadecola C. Meairs S. A concerted appeal for international cooperation in preclinical stroke research. Stroke. 44 (2013), 6, S. 1754–1760. DOI dx.doi.org/10.1161/STROKEAHA.113.000734
Doose G, Alexis M, Kirsch R, Findeis S, Langenberger D, Machne R, Mörl M, Hoffmann S, Stadler PF. Mapping the RNA-Seq trash bin: Unusual transcripts in prokaryotic transcriptome sequencing data. RNA biology 10 (2013), Nr. 7, S. 1204–1210. DOI dx.doi.org/10.4161/rna.24972
Faust D, Kletting S, Ueberham E, Dietrich C. Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells. Toxicology letters. 223 (2013), 1, S. 73–80. DOI dx.doi.org/10.1016/j.toxlet.2013.08.022
Fricke S, Hilger N, Fricke C, Schönfelder U, Behre G, Ruschpler P, Boldt A, Oelkrug C, Sack U, Emmrich F. Prevention of graft-versus-host-disease with preserved graft-versus-leukemia-effect by ex vivo and in vivo modulation of CD4+ T-cells. Cellular and Molecular Life Sciences. 2013 Sep 26. [Epub ahead of print]
Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, Lemere CA. Pyroglutamate-3 amyloid-beta deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models. Am J Pathol. 2013 Aug;183(2):369-81. DOI dx.doi.org/10.1016/j.ajpath.2013.05.005 Epub 2013 Jun 7.
Güttler BH, Cynis H, Seifert F, Ludwig HH, Porzel A, Schilling S. A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues. Amino Acids. 44 (2013), 4, S. 1205–14. DOI dx.doi.org/10.1007/s00726-012-1454-0
Hass J, Walton E, Kirsten H, Liu J, Priebe L, Wolf C, Karbalai N, Gollub R, White T, Roessner V, Müller KU, Paus T, Smolka MN, Schumann G, IMAGEN Consortium, Scholz M, Cichon S, Calhoun V, Ehrlich S. A genome-wide association study suggests novel loci associated with a Schizophrenia-related brain-based phenotype. PLoS One. 8 (2013), 6, e64872. DOI dx.doi.org/10.1371/journal.pone.0064872
Hellvard A, Maresz K, Schilling S, Graubner S, Heiser U, Jonsson R, Cynis H, Demuth HU, Potempa J, Mydel P. Glutaminyl cyclases as novel targets for the treatment of septic arthritis. Journal of Infectious Diseases. 207 (2013), 5, S. 768–77. DOI dx.doi.org/10.1093/infdis/jis729
Hodzic M, Naaldijk Y, Stolzing A. Regulating aging in adult stem cells with microRNA. Zeitschrift für Gerontologie und Geriatrie. 46 (2013), 7, S. 629–34. DOI dx.doi.org/10.1007/s00391-013-0531-7
Holland H, Xu LX, Ahnert P, Kirsten H, Koschny R, Bauer M, Schober R, Meixensberger J, Krupp W. Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma. Pathology – research and practice. 209 (2013), 9, S. 541–7. DOI dx.doi.org/10.1016/j.prp.2013.06.001
Hubicka J, Jost J, Long Y, Stadler PF, Yang L. Relations between graphs. Ars mathematica contemporanea 6 (2013), Nr. 2, S. 323–350.
Jiang SN, Park SH, Lee HJ, Zheng JH, Kim HS, Bom HS, Hong Y, Szardenings M, Shin MG, Kim SC, Ntziachristos V, Choy HE, Min JJ. Engineering of bacteria for the visualization of targeted delivery of a cytolytic anticancer agent. Molecular Therapy. 21 (2013), 11, S. 1985–95. DOI dx.doi.org/10.1038/mt.2013.183
Kehlen A, Haegele M, Menge K, Gans K, Immel UD, Hoang-Vu C, Klonisch T, Demuth HU. Role of glutaminyl cyclases in thyroid carcinomas. Endocr Relat Cancer. 2013 Feb 18;20(1):79-90. DOI dx.doi.org/10.1530/ERC-12-0053 Print 2013 Feb.
Kolenko P, Koch B, Rahfeld JU, Schilling S, Demuth HU, Stubbs MT. Structure of glutaminyl cyclase from Drosophila melanogaster in space group I4. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69 (Pt 4): 358-61. DOI dx.doi.org/10.1107/S1744309113005575 Epub 2013 Mar 28.
Langenberger D, Cakir MV, Hoffmann S, Stadler PF. Dicer-processed small RNAs: Rules and exceptions. Journal of experimental zoology. Part B, Molecular and developmental evolution 320B (2013), Nr. 1, S. 35–46. DOI dx.doi.org/10.1002/jez.b.22481
Lechner M, Marz M, Ihling C, Sinz A, Stadler PF, Krauss V. The correlation of genome size and DNA methylation rate in metazoans. Theory in Biosciences 132 (2013), Nr. 1, S. 47–60. DOI dx.doi.org/10.1007/s12064-012-0167-y
Lehmann J, Stadler PF, Krauss V. Near intron pairs and the metazoan tree. Molecular phylogenetics and evolution 66 (2013), Nr. 3, S. 811–823. DOI dx.doi.org/10.1016/j.ympev.2012.11.012
Lipfert J, Ödemis V, Wagner DC, Boltze J, Engele J. CXCR4 and CXCR7 form a functional receptor unit for SDF-1/CXCL12 in primary rodent microglia. Neuropathology and applied neurobiology. 39 (2013), 6, S. 667–80. DOI dx.doi.org/10.1111/nan.12015
Lison H, Happel MF, Schneider F, Baldauf K, Kerbstat S, Seelbinder B, Schneeberg J, Zappe M, Goldschmidt J, Budinger E, Schröder UH, Ohl FW, Schilling S, Demuth HU, Scheich H, Reymann KG, Rönicke R. Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death. Neurobiol Dis. 2014 Mar;63:62-73. DOI dx.doi.org/10.1016/j.nbd.2013.11.014 Epub 2013 Nov 27.
Lobsien D, Dreyer AY, Stroh A, Boltze J, Hoffmann KT. Imaging of VSOP labeled stem cells in agarose phantoms with susceptibility weighted and T2* weighted MR Imaging at 3T: determination of the detection limit. PLoS One. 8 (2013), 5, e62644. DOI dx.doi.org/10.1371/journal.pone.0062644
Mitzner S. Stellenwert der MARS-Dialyse beim Acute-on-chronic-Leberversagen. Zeitschrift für Gastroenterologie. 51 (2013), 10, S. 1193–4. DOI dx.doi.org/10.1055/s-0033-1350351
Mitzner SR, Gloger M, Henschel J, Koball S. Improvement of hemodynamic and inflammatory parameters by combined hemoadsorption and hemodiafiltration in septic shock: a case report. Blood Purification. 35 (2013),4, S. 314–5. DOI dx.doi.org/10.1159/000351206
Müller SA, Findeiß S, Pernitzsch SR, Wissenbach DK, Stadler PF, Hofacker IL, Bergen M. von, Kalkhof S. Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics. Journal of Proteomics 86 (2013), S. 27–42. DOI dx.doi.org/10.1016/j.jprot.2013.04.036
Pachernegg S, Joshi I, Muth-Köhne E, Pahl S, Münster Y, Terhag J, Karus M, Werner M, Ma-Högemeier ZL, Körber C, Grunwald T, Faissner A, Wiese S, Hollmann M. Undifferentiated embryonic stem cells express ionotropic glutamate receptor mRNAs. Frontiers in Neuroscience. 7 (2013), 241, 12 S. DOI dx.doi.org/10.3389/fncel.2013.00241
Pönisch W, Moll B, Bourgeois M, Andrea M, Schliwa T, Heyn S, Schmalfeld M, Edelmann T, Becker C, Hoffmann FA, Schwarzer A, Kreibich U, Egert M, Stiegler R, Krahl R, Remane Y, Bachmann A, Lindner T, Weidhase L, Petros S, Fricke S, Vucinic V, Al Ali H, Niederwieser D. Bendamustine and prednisone in combination with bortezomib (BPV) in the treatment of patients with relapsed or refractory multiple myeloma and light chain-induced renal failure. Journal of Cancer Research and Clinical Oncology. 139 (2013), 11, S. 1937–46. DOI dx.doi.org/10.1007/s00432-013-1513-2
Ramsbeck D., Buchholz M., Koch B., Böhme S., Hoffmann T., Demuth H-U, Heiser U. Structure-activity relationships of benzimidazole-based glutaminyl cyclase inhibitors featuring a heteroaryl scaffold. Journal of Medicinal Chemistry.56 (2013), 17, S. 6613–25. DOI dx.doi.org/10.1021/jm4001709
Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J. RNAsnp: Efficient detection of local RNA secondary structure changes induced by SNPs. Human mutation 34 (2013), Nr. 4, S. 546–556. DOI dx.doi.org/10.1002/humu.22273
Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J. The RNAsnp web server: predicting SNP effects on local RNA secondary structure. Nucleic Acids Research 41 (2013), Nr. W1, S. W475–W479. DOI dx.doi.org/10.1093/nar/gkt291
Sack U, Barnett D, Demirel GY, Fossat C, Fricke S, Kafassi N, Nebe T, Psarra K, Steinmann J, Lambert C. Accreditation of flow cytometry in Europe. Cytometry B Clinical Cytometry. 84 B (2013), 3, S. 135–42. DOI dx.doi.org/10.1002/cyto.b.21079
Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR. Role of different replacement fluids during extracorporeal treatment in a pig model of sepsis. Therapeutic Apheresis and Dialysis. 17 (2013), 1, S. 84–92. DOI dx.doi.org/10.1111/j.1744-9987.2012.01103.x
Schreiber R, Luong N, Fan Z, Kuzyk A, Nickels PC, Zhang T, Smith DM, Yurke B, Kuang W, Govorov AO, Liedl T. Chiral plasmonic DNA nanostructures with switchable circular dichroism. Nature Communations. 4 (2013), 2948. DOI dx.doi.org/10.1038/ncomms3948
Smith D, Schüller V, Engst C, Rädler J, Liedl T. Nucleic acid nanostructures for biomedical applications. Nanomedicine. 8 (2013), 1, S. 105–21. DOI dx.doi.org/10.2217/nnm.12.184
Stolzing A, Haendeler J. Aging-mechanisms, models, and translation. Zeitschrift für Gerontologie und Geriatrie. 46 (2013), 7, S. 612. DOI dx.doi.org/10.1007/s00391-013-0528-2
Sun N, Hartmann R, Lecher J, Stoldt M, Funke SA, Gremer L, Ludwig HH, Demuth HU, Kleinschmidt M, Willbold D. Structural analysis of the pyroglutamate-modified isoform of the Alzheimer‘s disease-related amyloid-β using NMR spectroscopy. J Pept Sci. 2012 Nov;18(11):691-5. DOI dx.doi.org/10.1002/psc.2456 Epub 2012 Sep 24
Tessema B, Beer J, Merker M, Emmrich F, Sack U, Rodloff AC, Niemann S. Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia. BMC Infectious Diseases. 13 (2013), 131. DOI dx.doi.org/10.1186/1471-2334-13-131
Wachsmuth M, Findeiß S, Weissheimer N, Stadler PF, Mörl M. De novo design of a synthetic riboswitch that regulates transcription termination. Nucleic Acids Research 41 (2013), Nr. 4, S. 2541–2551. DOI dx.doi.org/10.1093/nar/gks1330
Wagner DC, Scheibe J, Glocke I, Weise G, Deten A, Boltze J, Kranz A. Object-based analysis of astroglial reaction and astrocyte subtype morphology after ischemic brain injury. Acta Neurobiologiae Experimentals. 73 (2013), 1, S. 79–87.
Will S, Siebauer MF, Heyne S, Engelhardt J, Stadler PF, Reiche K, Backofen R. LocARNAscan: incorporating thermodynamic stability in sequence and structure-based RNA homology search. Algorithms for Molecular Biology. 8 (2013), 1, 14. DOI dx.doi.org/10.1186/1748-7188-8-14

Publikationen 2012

Arnold A, Naaldijk YM, Fabian C, Wirth H, Binder H, Nikkhah G, Armstrong L, Stolzing A. Reprogramming of Human Huntington Fibroblasts Using mRNA. ISRN Cell Biology, Volume 2012 (2012), Article ID 124878, 12 pages. DOI dx.doi.org/10.5402/2012/124878 Article
Averill MM, Kerkhoff C, Bornfeldt KE. S100A8 and S100A9 in cardiovascular biology and disease. Arterioscler Thromb Vasc Biol. 32 (2012), 2, S. 223-9. DOI dx.doi.org/10.1161/ATVBAHA.111.236927
Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, Saliba F, Sauerbruch T, Klammt S, Ockenga J, Pares A, Wendon J, Brünnler T, Kramer L, Mathurin P, Mata MD, Gasbarrini A, Müllhaupt B, Wilmer A, Laleman W, Eefsen M, Sen S, Zipprich A, Tenorio T, Pavesi M, Schmidt HH, Mitzner S, Williams R, Arroyo V. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: The RELIEF trial. Hepatology. 2012. DOI dx.doi.org/10.1002/hep.26185 [Epub ahead of print]
Beer S, Gomez T, Dallinger D, Momber I, Marnay C, Stadler M, Lai J. An economic analysis of used electric vehicle batteries integrated into commercial building microgrids. IEEE transactions on smart grid 3 (2012), 1, S.517-525. DOI dx.doi.org/10.1109/TSG.2011.2163091
Boltze J, Kleinschnitz C, Reymann KG, Reiser G, Wagner DC, Kranz A, Michalski D; the meeting contributors. Neurovascular pathophysiology in cerebral ischemia, dementia and the ageing brain - current trends in basic, translational and clinical research. Exp Transl Stroke Med. 4 (2012), 1:14. DOI dx.doi.org/10.1186/2040-7378-4-14
Boltze J, Reich DM, Hau S, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Kamprad M, Stahl T. Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo. Cell Transplant. 21 (2012), 4, S. 723-737. DOI dx.doi.org/10.3727/096368911X586783
Boltze J, Schmidt UR, Reich DM, Kranz A, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Förschler A, Schäbitz WR. Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats. Cell Transplant. 21 (2012), 6, S. 1199-211. DOI dx.doi.org/10.3727/096368911X589609
Burkhardt J, Kirsten H, Holland H, Krupp W, Ligges C, Quente E, Boltze J, Ahnert P, Wilcke A. Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort. Psychiatric Genetics. 22 (2012), 6, S. 307-308. DOI dx.doi.org/10.1097/YPG.0b013e328353aeae
Burkhardt J, Kirsten H, Wolfram G, Quente E, Ahnert P. Differential allelic expression of IL13 and CSF2 genes associated with asthma. Genetics and molecular biology, 35(2012), 3, S. 567-574. DOI dx.doi.org/10.1590/S1415-47572012005000055
Colley H, McArthur SL, Stolzing A, Scutt A. Culture on fibrin matrices maintains the colony-forming capacity and osteoblastic differentiation of mesenchymal stem cells. Biomed Mater. 7 (2012), 4:045015. DOI dx.doi.org/10.1088/1748-6041/7/4/045015
De Filette M, Ulbert S, Diamond M, Sanders NN. Recent progress in West Nile virus diagnosis and vaccination. Vet Res.43 (2012), 1, S. 16. DOI dx.doi.org/10.1186/1297-9716-43-16
Engelhardt J, Stadler PF. Hidden treasures in unspliced EST data. Theory in Biosciences 131 (2012), 1, S.49-57. DOI dx.doi.org/10.1007/s12064-012-0151-6
Fricke S, Fricke C, Oelkrug C, Blatz R, Schönfelder U, Niederwieser D, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR for the detection and characterisation of Aspergillus species. Mycoses. 55 (2012), 5, S. 416-25. DOI dx.doi.org/10.1111/j.1439-0507.2011.02161.x
Fricke S, Rothe K, Hilger N, Ackermann M, Oelkrug C, Fricke C, Schönfelder U, Niederwieser D, Emmrich F, Sack U. Allogeneic bone marrow grafts with high levels of CD4(+) CD25(+) FoxP3(+) T cells can lead to engraftment failure. Cytometry A. 81 (2012), 6, S. 476-88. DOI dx.doi.org/10.1002/cyto.a.22061
Fueldner C, Mittag A, Knauer J, Biskop M, Hepp P, Scholz R, Wagner U, Sack U, Emmrich F, Tárnok A, Lehmann J. Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry. Arthritis Res Ther. 14 (2012), 1:R8. DOI dx.doi.org/10.1186/ar3682
Fuellen G, Dengjel J, Hoeflich A, Hoeijemakers J, Kestler HA, Kowald A, Priebe S, Rebholz-Schuhmann D, Schmeck B, Schmitz U, Stolzing A, Sühnel J, Wuttke D, Vera J. Systems Biology and Bioinformatics in Aging Research: A Workshop Report. Rejuvenation Res. 15 (2012), 6, S. 631 -641. DOI dx.doi.org/10.1089/rej.2012.1360
Hellmuth M, Ostermeier L, Stadler PF. A survey on hypergraph products. Mathematics in Computer Science 6 (2012), 1, S.1-32. DOI dx.doi.org/10.1007/s11786-012-0109-6
Hellmuth M, Ostermeier L, Stadler PF. Diagonalized Cartesian products of S-prime graphs are S-prime. Discrete mathematics 312 (2012), 1, S.74-80. DOI dx.doi.org/10.1016/j.disc.2011.03.033
Hertel J, Bartschat S, Wintsche A, Otto C, Stadler PF. Evolution of the let-7 microRNA Family. RNA biology 9 (2012), 3, S.231-241. DOI dx.doi.org/10.4161/rna.9.3.18974
Hinz D, Bauer M, Röder S, Olek S, Huehn J, Sack U, Borte M, Simon JC, Lehmann I, Herberth G; for the LINA study group. Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year. Allergy. 67 (2012), 3, S. 380 - 389. DOI dx.doi.org/10.1111/j.1398-9995.2011.02767.x
Hinze A, Stolzing A. Microglia differentiation using a culture system for the expansion of mice non-adherent bone marrow stem cells. J Inflamm (Lond). 9 (2012), 1:12. DOI dx.doi.org/10.1186/1476-9255-9-12
Hofacker IL, Reidys CM, Stadler PF. Symmetric circular matchings and RNA folding. Discrete mathematics 312 (2012), 1, S.100-112. DOI dx.doi.org/10.1016/j.disc.2011.06.004
Holland H, Ahnert P, Koschny R, Kirsten H, Bauer M, Schober R, Meixensberger J, Fritzsch D, Krupp W. Detection of novel genomic aberrations in anaplastic astrocytomas by GTG-banding, SKY, locusspecific FISH, and high density SNP-array. Pathology, research and practice, 208 (2012), 6, S. 325-330. DOI dx.doi.org/10.1016/j.prp.2012.03.010
Johnson AA, Akman K, Calimport SR, Wuttke D, Stolzing A, de Magalhães JP. The role of DNA methylation in aging, rejuvenation, and age-related disease. Rejuvenation Res. 15 (2012), 5, S. 483-94. DOI dx.doi.org/10.1089/rej.2012.1324
Jühling F, Pütz J, Bernt M, Donath A, Middendorf M, Florentz C, Stadler PF. Improved systematic tRNA gene annotation allows new insights into the evolution of mitochondrial tRNA structures and into the mechanisms of mitochondrial genome rearrangements. Nucleic Acids Research 40 (2012), 7, S.2833-2845. DOI dx.doi.org/10.1093/nar/gkr1131
Jühling F, Putz J, Florentz C, Stadler PF. Armless mitochondrial tRNAs in enoplea (nematoda). RNA biology 9 (2012), 9, S.1161-1166. DOI dx.doi.org/10.4161/rna.21630
Kerkhoff C, Voss A, Scholzen TE, Averill MM, Zänker KS, Bornfeldt KE. Novel insights into the role of S100A8/A9 in skin biology. Exp Dermatol. 21 (2012), 11, S. 822 - 6. DOI dx.doi.org/10.1111/j.1600-0625.2012.01571.x
Kielstein JT, Beutel G, Fleig S, Steinhoff J, Meyer TN, Hafer C, Kuhlmann U, Bramstedt J, Panzer U, Vischedyk M, Busch V, Ries W, Mitzner S, Mees S, Stracke S, Nürnberger J, Gerke P, Wiesner M, Sucke B, Abu-Tair M, Kribben A, Klause N, Schindler R, Merkel F, Schnatter S, Dorresteijn EM, Samuelsson O, Brunkhorst R; Collaborators of the DGfN STEC-HUS registry. Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome: an analysis of the German STEC-HUS registry. Nephrol Dial Transplant. 27 (2012), 10, S. 3807-15. DOI dx.doi.org/10.1093/ndt/gfs394
Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatric Genetics. 22 (2012), 4, S. 216-217. DOI dx.doi.org/10.1097/YPG.0b013e32834c0c97
Klammt S, Wojak HJ, Mitzner A, Koball S, Rychly J, Reisinger EC, Mitzner S. Albumin-binding capacity (ABiC) is reduced in patients with chronic kidney disease along with an accumulation of protein-bound uraemic toxins. Nephrol Dial Transplant. 27 (2012), 6, S. 2377-83. DOI dx.doi.org/10.1093/ndt/gfr616
Klemm K, Mehta A, Stadler PF. Landscape encodings enhance optimization. PLoS one. Online journal 7 (2012), 4, Art. E34780. DOI dx.doi.org/10.1371/journal.pone.0034780
Klionsky DJ and 1269 others. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8 (2012), 4, S. 445 - 544. DOI dx.doi.org/10.4161/auto.19496
Koch H, Graneist C, Emmrich F, Till H, Metzger R, Aupperle H, Schierle K, Sack U, Boldt A. Xenogenic esophagus scaffolds fixed with several agents: comparative in vivo study of rejection and inflammation. J Biomed Biotechnol. 2012; 2012:948320. DOI dx.doi.org/10.1155/2012/948320
Kuhlmeier D, Sandetskaya N, Allelein S. Application of nanotechnology in miniaturized systems and its use in medical and food analysis. Recent Pat Food Nutr Agric. 4 (2012), 3, S. 187-99. DOI dx.doi.org/10.2174/2212798411204030187
Lange F, Sack U. Gelenkentzündungen : Modellsysteme für die Arthritisforschung. GIT Spezial BIOforum 1/2012, S. 28-30. GIT Labor-Fachzeitschrift 56 (2012), 6, S. 459-461. Artikel
Langenberger D, Pundhir S, Ekstrom CT, Stadler PF, Hoffmann S, Gorodkin J. deepBlockAlign: A tool for aligning RNA-seq profiles of read block patterns. Bioinformatics 28 (2012), 1, S.17-24. DOI dx.doi.org/10.1093/bioinformatics/btr598
Leichsenring A, Lange F. Tiermodelle in der präklinischen Forschung. GIT Labor-Fachzeitschrift 56 (2012), 12, S. 848–849. Artikel
Maletzki C, Bodammer P, Breitrück A, Kerkhoff C. S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma. Hepat Mon. 2012, 12 (10 HCC):e7240. DOI dx.doi.org/10.5812/hepatmon.7240
Michalski D, Heindl M, Kacza J, Laignel F, Küppers-Tiedt L, Schneider D, Grosche J, Boltze J, Löhr M, Hobohm C, Härtig W. Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation. Eur J Histochem. 2012, 56(2):e14. DOI dx.doi.org/10.4081/ejh.2012.14
Möller K, Stahl T, Boltze J, Wagner DC. Isolation of inflammatory cells from rat brain tissue after stroke. Exp Transl Stroke Med. 4 (2012), 1:20. DOI dx.doi.org/10.1186/2040-7378-4-20
Naaldijk Y, Staude M, Fedorova V, Stolzing A. Effect of different freezing rates during cryopreservation of rat mesenchymal stem cells using combinations of hydroxyethyl starch and dimethylsulfoxide. BMC Biotechnol. (2012) 12:49. DOI dx.doi.org/10.1186/1472-6750-12-49
Ostermeier L, Hellmuth M, Stadler PF. The Cartesian product of hypergraphs. Journal of Graph Theory 70 (2012), 2, S.180-196. DOI dx.doi.org/10.1002/jgt.20609
Otto C, Reiche K, Hackermüller J. Detection of differentially expressed segments in tiling array data. In: Bioinformatics 28 (2012), 11, S.1471-1479. DOI dx.doi.org/10.1093/bioinformatics/bts142
Otto C, Stadler PF, Hoffmann S. Fast and sensitive mapping of bisulfite-treated sequencing data. Bioinformatics 28 (2012), 13, S.1698-1704. DOI dx.doi.org/10.1093/bioinformatics/bts254
Pohler P, Lehmann J, Veneruso V, Tomm J, v. Bergen M, Lambrecht B, Kohn B, Weingart C, Müller TH, Seltsam A. Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model. Transfusion. 52 (2012), 11, S. 2414-26. DOI dx.doi.org/10.1111/j.1537-2995.2012.03583.x
Polchow B, Kebbel K, Schmiedeknecht G, Reichardt A, Henrich W, Hetzer R, Lueders C. Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks. J Transl Med. 2012; 10:98. DOI dx.doi.org/10.1186/1479-5876-10-98
Pösel C, Möller K, Fröhlich W, Schulz I, Boltze J, Wagner DC. Density gradient centrifugation compromises bone marrow mononuclear cell yield. PLoS One. 7 (2012), 12:e50293. DOI dx.doi.org/10.1371/journal.pone.0050293
Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR. Plasma separation by centrifugation and subsequent plasma filtration: impact on survival in a pig model of sepsis. Ther Apher Dial. 16 (2012), 3, S. 205-12. DOI dx.doi.org/10.1111/j.1744-9987.2011.01055.x
Sauer M, Haubner C, Mencke T, Nöldge-Schomburg G, Mitzner S, Altrichter J, Stange J. Impaired cell functions of hepatocytes incubated with plasma of septic patients. Inflamm Res. 61 (2012), 6, S. 609-16. DOI dx.doi.org/10.1007/s00011-012-0451-9
Schmidtke C, Findeiß S, Sharma CM, Kuhfuß J, Hoffmann S, Vogel J, Stadler PF, Bonas U. Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions. Nucleic Acids Research 40 (2012), 5, S.2020-2031. DOI dx.doi.org/10.1093/nar/gkr904
Scholbach J, Schulz A, Westphal F, Egger D, Wege AK, Patties I, Köberle M, Sack U, Lange F. Comparison of hematopoietic stem cells derived from fresh and cryopreserved whole cord blood in the generation of humanized mice. PLoS One. 7 (2012), 10:e46772. DOI dx.doi.org/10.1371/journal.pone.0046772
Stolzing A, Bauer E, Scutt A. Suspension cultures of bonemarrow-derived mesenchymal stem cells: effects of donor age and glucose level. Stem Cells Dev. 21 (2012), 14, S. 2718-23. DOI dx.doi.org/10.1089/scd.2011.0406
Stolzing A, Naaldijk Y, Fedorova V, Sethe S. Hydroxyethylstarch in cryopreservation - mechanisms, benefits and problems. Transfus Apher Sci. 46 (2012), 2, S. 137-47. DOI dx.doi.org/10.1016/j.transci.2012.01.007
Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B, Klaesner B, Zhu C, Schwarzmaier S, Meissner L, Mamrak U, Engel DC, Drzezga A, Patel RP, Blomgren K, Barthel H, Boltze J, Kuebler WM, Plesnila N. Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles. Circ Res. 110 (2012), 5, S. 727-38. DOI dx.doi.org/10.1161/CIRCRESAHA.111.253419
Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. Analysis of gene mutations associated with isoniazid, rifampicin and ethambutol resistance among Mycobacterium tuberculosis isolates from Ethiopia. BMC Infect Dis. 12 (2012) :37. DOi dx.doi.org/10.1186/1471-2334-12-37
Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. First- and second-line anti-tuberculosis drug resistance in Northwest Ethiopia. Int J Tuberc Lung Dis. 16 (2012), 6 S. 805-11. DOI dx.doi.org/10.5588/ijtld.11.0522
Tippmann SC, Ivanek R, Gaidatzis D, Scholer A, Hoerner L, Nimwegen E. van, Stadler PF, Stadler MB, Schubeler D. Chromatin measurements reveal contributions of synthesis and decay to steady-state mRNA levels. Molecular systems biology 8 (2012), Art.593. DOI dx.doi.org/10.1038/msb.2012.23
Voss A, Bode G, Kerkhoff C. Double-stranded RNA induces IL-8 and MCP-1 gene expression via TLR3 in HaCaTkeratinocytes. Inflamm Allergy Drug Targets. 11 (2012), 5, S. 397-405.
Voss A, Gescher K, Hensel A, Nacken W, Zänker KS, Kerkhoff C. Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor. FEBS Lett. 586 (2012), 2, S. 196-203. DOI dx.doi.org/10.1016/j.febslet.2011.12.022
Wagner DC, Bojko M, Peters M, Lorenz M, Voigt C, Kaminski A, Hasenclever D, Scholz M, Kranz A, Weise G, Boltze J. Impact of age on the efficacy of bone marrow mononuclear cell transplantation in experimental stroke. Exp Transl Stroke Med. 24(2012), 1:17. DOI dx.doi.org/10.1186/2040-7378-4-17
Wagner DC, Deten A, Härtig W, Boltze J, Kranz A. Changes in T2 relaxation time after stroke reflect clearing processes. Neuroimage.61 (2012), 4, S. 780-5. DOi dx.doi.org/10.1016/j.neuroimage.2012.04.023
Weise G, Stoll G. Magnetic resonance imaging of blood brain/nerve barrier dysfunction and leukocyte infiltration: closely related or discordant? Front Neurol. 2012; 3:178. DOi dx.doi.org/10.3389/fneur.2012.00178
Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H. Imaging genetics of FOXP2 in dyslexia. European Journal of Human Genetics, 20 (2012), 2, S. 224-229. DOI dx.doi.org/10.1038/ejhg.2011.160
Will S, Joshi T, Hofacker IL, Stadler PF, Backofen R. LocARNA-P: Accurate boundary prediction and improved detection of structural RNAs. RNA 18 (2012), 5, S.900-914. DOI dx.doi.org/10.1261/rna.029041.111
Wuttig D, Zastrow S, Füssel S, Toma MI, Meinhardt M, Kalman K, Junker K, Sanjmyatav J, Boll K, Hackermüller J, Rolle A, Grimm M-O, Wirth MP. CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases. International journal of cancer 131 (2012), 5, S.E693-E704. DOI dx.doi.org/10.1002/ijc.27419

Publikationen 2011

Boltze J, Kranz A, Wagner DC, Reymann K, Reiser G, Hess DC. Recent advances in basic and translational stroke research. Expert Rev Neurother. 2011 Feb;11(2):199-202.
Boltze J, Nitzsche B, Geiger KD, Schoon HA. Histopathological investigation of different MCAO modalities and impact of autologous bone marrow mononuclear cell administration in an Ovine stroke model. Translational Stroke Research 2 (2011), 3, S.279-293. DOI dx.doi.org/10.1007/s12975-011-0101-5
Boltze J, Reich DM, Hau S, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Kamprad M, Stahl T. Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo. Cell Transplant. 2011 Sep 16. DOI dx.doi.org/10.3727/096368911X586783 [Epub ahead of print]
Boltze J, Schmidt UR, Reich DM, Kranz A, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Förschler A, Schäbitz WR. Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats. Cell Transplant. 2011 Dec 13. DOI dx.doi.org/10.3727/096368911X589609 [Epub ahead of print]
Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, Gingeras TR, Mattick JS. The reality of pervasive transcription. PLoS Biol. 9 (2011), 7, e1000625; discussion e1001102. DOI dx.doi.org/10.1371/journal.pbio.1000625
Efimenko A, Starostina E, Kalinina N, Stolzing A. (2011) Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. J Transl Med. Jan 18;9(1):10. DOI dx.doi.org/10.1186/1479-5876-9-10 Article
Eggenhofer F, Tafer H, Stadler PF, Hofacker IL. RNApredator : fast accessibility-based prediction of sRNA targets. Nucleic Acids Res. 39 (2011), Supl. 2, W149-54. DOI dx.doi.org/10.1093/nar/gkr467
Fangmann J, Kathrin Al-Ali H, Sack U, Kamprad M, Tautenhahn HM, Faber S, Hauss J, Niederwieser D, Lindner T, Bachmann A. Kidney transplant from the same donor without maintenance immunosuppression after previous hematopoietic stem cell transplant. Am J Transplant. 11 (2011), 1, S. 156 - 62. DOI dx.doi.org/10.1111/j.1600-6143.2010.03352.x
Fasold M, Langenberger D, Binder H, Stadler PF, Hoffmann S. DARIO: a ncRNA detection and analysis tool for next-generation sequencing experiments. Nucleic Acids Res. 39 (2011), Supl. 2, S. W112-7. DOI dx.doi.org/10.1093/nar/gkr357
Findeiss S, Engelhardt J, Prohaska SJ, Stadler PF. Protein-coding structured RNAs: A computational survey of conserved RNA secondary structures overlapping coding regions in drosophilids. Biochimie. 93 (2011), 11, S. 2019-23. DOI dx.doi.org/10.1016/j.biochi.2011.07.023
Findeiss S, Langenberger D, Stadler PF, Hoffmann S. Traces of post-transcriptional RNA modifications in deep sequencing data. Biol Chem. 2392 (2011), 4, S. 305-13. DOI dx.doi.org/10.1515/bc.2011.043
Fricke S, Fricke C, Oelkrug C, Blatz R, Schönfelder U, Niederwieser D, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR for the detection and characterisation of Aspergillus species. Mycoses. 2011 Dec 11. DOI dx.doi.org/10.1111/j.1439-0507.2011.02161.x [Epub ahead of print]
Grey D, Sack U, Scholz M, Knaack H, Fricke S, Oppel C, Luderer D, Fangmann J, Emmrich F, Kamprad M. Increased CD64 expression on polymorphonuclear neutrophils indicates infectious complications following solid organ transplantation. Cytometry A. 79 (2011), 6, S. 446 - 60. DOI dx.doi.org/10.1002/cyto.a.21049
Hinze A, Stolzing A. (2011) Differentiation of mouse bone marrow derived stem cells toward microglia. BMC Cell Biology. Aug 19;12(1):35. DOI dx.doi.org/10.1186/1471-2121-12-35 Article
Holland H, Livrea M, Ahnert P, Koschny R, Kirsten H, Meixensberger J, Bauer M, Schober R, Fritzsch D, Krupp W. Intracranial hemangiopericytoma: Case study with cytogenetics and genome wide SNP-A analysis. Pathol Res Pract. 2011 Feb 7. [Epub ahead of print]
Jühling F, Pütz J, Bernt M, Donath A, Middendorf M, Florentz C, Stadler PF. Improved systematic tRNA gene annotation allows new insights into the evolution of mitochondrial tRNA structures and into the mechanisms of mitochondrial genome rearrangements. Nucleic Acids Res. 2011 Dec 1. [Epub ahead of print] DOI dx.doi.org/10.1093/nar/gkr1131
Kehr S, Bartschat S, Stadler PF, Tafer H. PLEXY : efficient target prediction for box C/D snoRNAs. Bioinformatics. 27 (2011), 2, S. 279-80. DOI dx.doi.org/10.1093/bioinformatics/btq642
Kim M, Garant KA, Zur Nieden N, Alain T, Loken SD, Urbanski SJ, Forsyth PA, Rancourt D, Lee PW, Johnston RN. Attenuated reovirus displays oncolysis with reduced host toxicity. The British journal of cancer. 104 (2011), 2, S. 290 - 299. DOI dx.doi.org/10.1038/sj.bjc.6606053
Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatr Genet. 2011 Sep 20. DOI dx.doi.org/10.1097/YPG.0b013e32834c0c97 [Epub ahead of print].
Knauer J, Krupka I, Fueldner C, Lehmann J, Straubinger RK. Evaluation of the preventive capacities of a topically applied azithromycin formulation against Lyme borreliosis in a murine model. J Antimicrob Chemother. 66 (2011), 12, S. 2814 - 2822. DOI dx.doi.org/10.1093/jac/dkr371
Krakauer DC, Collins JP, Erwin D, Flack JC, Fontana W, Laubichler MD, Prohaska SJ, West GB, Stadler PF. The challenges and scope of theoretical biology. J Theor Biol. 276 (2011), 1, S. 269-76. DOI dx.doi.org/10.1016/j.jtbi.2011.01.051
Lechner M, Findeiss S, Steiner L, Marz M, Stadler PF, Prohaska SJ. Proteinortho : detection of (co-)orthologs in large-scale analysis. BMC Bioinformatics. 12 (2011), 124, 9 S. DOI dx.doi.org/10.1186/1471-2105-12-124
Marz M, Stadler PF. RNA interactions. Adv Exp Med Biol. 722 (2011), S. 20-38. DOI dx.doi.org/10.1007/978-1-4614-0332-6_2
Menzel P, Stadler PF, Gorodkin J. MaxAlike : maximum likelihood-based sequence reconstruction with application to improved primer design for unknown sequences. Bioinformatics. 27 (2011), 3, S. 317-25. DOI dx.doi.org/10.1093/bioinformatics/btq651
Michalski D, Pelz J, Weise C, Kacza J, Boltze J, Grosche J, Kamprad M, Schneider D, Hobohm C, Härtig W. Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke. Exp Transl Stroke Med. 3 (2011), 5, 9 S. DOI dx.doi.org/10.1186/2040-7378-3-5
Mocker K, Holland H, Ahnert P, Schober R, Bauer M, Kirsten H, Koschny R, Meixensberger J, Krupp W. Multiple meningioma with different grades of malignancy: case report with genetic analysis applying single-nucleotide polymorphism array and classical cytogenetics. Pathol Res Pract. 2011 Jan 15;207(1):67-72.
Oschatz C, Maas C, Lecher B, Jansen T, Björkqvist J, Tradler T, Sedlmeier R, Burfeind P, Cichon S, Hammerschmidt S, Müller-Esterl W, Wuillemin WA, Nilsson G, Renné T. Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity. 34 (2011), 2, S. 258-68. DOI dx.doi.org/10.1016/j.immuni.2011.02.008
Otto C, Hoffmann S, Gorodkin J, Stadler PF. Fast local fragment chaining using sum-of-pair gap costs. Algorithms Mol Biol. 6 (2011), 4, 8 S. DOI dx.doi.org/10.1186/1748-7188-6-4
Paulsen K, Tauber S, Timm J, Goelz N, Dumrese C, Stolzing A, Hass R, Ullrich O. (2011) The cannabinoid receptors agonist WIN55212-2 inhibits macrophageal differentiation and alters expression and phosphorylation of cell cycle control proteins. Cell Commun Signal. Dec 28;9(1):33.
Perseke M, Hetmank J, Bernt M, Stadler PF, Schlegel M, Bernhard D. The enigmatic mitochondrial genome of Rhabdopleura compacta (Pterobranchia) reveals insights into selection of an efficient tRNA system and supports monophyly of Ambulacraria. BMC Evol Biol. 11 (2011), 134, 12 S. DOI dx.doi.org/10.1186/1471-2148-11-134
Raincrow JD, Dewar K, Stocsits C, Prohaska SJ, Amemiya CT, Stadler PF, Chiu CH. Hox clusters of the bichir (Actinopterygii, Polypterus senegalus) highlight unique patterns of sequence evolution in gnathostome phylogeny. J Exp Zool B Mol Dev Evol. 16 (2011), 6, S. 451-64. DOI dx.doi.org/10.1002/jez.b.21420
Reidys CM, Huang FW, Andersen JE, Penner RC, Stadler PF, Nebel ME. Topology and prediction of RNA pseudoknots. Bioinformatics. 27 (2011), 8, S. 1076-85. DOI dx.doi.org/10.1093/bioinformatics/btr090
Riegelsberger UM, Deten A, Pösel C, Zille M, Kranz A, Boltze J, Wagner DC. Intravenous human umbilical cord blood transplantation for stroke: impact on infarct volume and caspase-3-dependent cell death in spontaneously hypertensive rats. Exp Neurol. 2011 Jan;227(1):218-23. Epub 2010 Nov 16.
Roesler U, Szabo I, Matthies C, Albrecht K, Leffler M, Scherer K, Nöckler K, Lehmann J, Methner U, Hensel A, Truyen U. Comparing validation of four ELISA-systems for detection of Salmonella derby- and Salmonella infantis-infected pigs. Berl Munch Tierarztl Wochenschr. 124 (2011), 7-8, S. 265-71. DOI dx.doi.org/10.2376/0005-9366-124-265
Rose D, Hiller M, Schutt K, Hackermüller J, Backofen R, Stadler PF. Computational discovery of human coding and non-coding transcripts with conserved splice sites. Bioinformatics. 27 (2011), 14, S. 1894-900. DOI dx.doi.org/10.1093/bioinformatics/btr314
Rupf S, Idlibi AN, Marrawi FA, Hannig M, Schubert A, von Mueller L, Spitzer W, Holtmann H, Lehmann A, Rueppell A, Schindler A. Removing biofilms from microstructured titanium ex vivo: a novel approach using atmospheric plasma technology. PLoS One.6 (2011), 10, e25893, 9 S. DOI dx.doi.org/10.1371/journal.pone.0025893
Schneeweiss A, Chabierski S, Salomo M, Delaroque N, Al-Robaiy S, Grunwald T, Bürki K, Liebert UG, Ulbert S. A DNA vaccine encoding the E protein of West Nile Virus is protective and can be boosted by recombinant domain DIII. Vaccine, 29 (2011), S. 6352-6357.
Schubert K, Polte T, Bönisch U, Schader S, Holtappels R, Hildebrandt G, Lehmann J, Simon JC, Anderegg U, Saalbach A. Thy-1 (CD90) regulates the extravasation of leukocytes during inflammation. Eur J Immunol. 41 (2011), 3, S. 645 - 656. DOI dx.doi.org/10.1002/eji.201041117
Skardelly M, Gaber K, Burdack S, Scheidt F, Hilbig H, Boltze J, Förschler A, Schwarz S, Schwarz J, Meixensberger J, Schuhmann MU. Long-term benefit of human fetal neuronal progenitor cell transplantation in a clinically adapted model after traumatic brain injury. J Neurotrauma. 28 (2011), 3, S. 401-14. DOI dx.doi.org/10.1089/neu.2010.1526
Smith DM, Schüller V, Forthmann C, Schreiber R, Tinnefeld P, Liedl T. A structurally variable hinged tetrahedron framework from DNA origami. J. Nuc. Acid., 2011. DOI dx.doi.org/10.4061/2011/360954
Stolzing A, Colley H, Scutt A. (2011) Effect of age and diabetes on the response of mesenchymal progenitor cells to fibrin matrices. Int J Biomater. 2011; 378034. Epub 2011 Dec 13. DOI dx.doi.org/10.1155/2011/378034 Article
Tafer H, Amman F, Eggenhofer F, Stadler PF, Hofacker IL. Fast accessibility-based prediction of RNA-RNA interactions. Bioinformatics. 27 (2011), 14, S. 1934-40. DOI dx.doi.org/10.1093/bioinformatics/btr281
Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B, Klaesner B, Zhu C, Schwarzmaier S, Meissner L, Mamrak U, Engel DC, Drzezga A, Patel RP, Blomgren K, Barthel H, Boltze J, Kuebler WM, Plesnila N. Inhalation of nitric oxide prevents Ischemic brain damage in experimental stroke by selective dilatation of Collateral Arterioles. Circ Res. 2011 Dec 29. DOI dx.doi.org/10.1161/CIRCRESAHA.111.253419 [Epub ahead of print]
Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. Rate of recovery of Mycobacterium tuberculosis from frozen acid-fast-bacillus smear-positive sputum samples subjected to long-term storage in Northwest Ethiopia. J Clin Microbiol. 49 (2011), 7, S. 2557 - 61. DOI dx.doi.org/10.1128/JCM.00059-11
Tramontano A, Donath A, Bernhart SH, Reiche K, Böhmdorfer G, Stadler PF, Bachmair A. Deletion analysis of the 3' long terminal repeat sequence of plant retrotransposon Tto1 identifies 125 base pairs redundancy as sufficient for first strand transfer. Virology. 412 (2011), 1, 75 - 82. DOI dx.doi.org/10.1016/j.virol.2010.12.059
Ulbert S. West Nile Virus: The Complex Biology of an Emerging Pathogen. Intervirology, 54 (2011), S. 171-184.
Ullrich A, Rohrschneider M, Scheuermann G, Stadler PF, Flamm C. In silico evolution of early metabolism. Artif Life. 17 (2011), 2, S. 87-108. DOI dx.doi.org/10.1162/artl_a_00021
Wagner DC, Riegelsberger UM, Michalk S, Härtig W, Kranz A, Boltze J. Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic. Brain Res. 2011 Mar 24;1381:237-42. Epub 2011 Jan 20.
Washietl S, Findeiss S, Müller SA, Kalkhof S, von Bergen M, Hofacker IL, Stadler PF, Goldman N. RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data. RNA. 17 (2011), 4, S. 578-94. DOI dx.doi.org/10.1261/rna.2536111
Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H. Imaging genetics of FOXP2 in dyslexia. Eur J Hum Genet. 20 (2012), 2, S. 224-9. DOI dx.doi.org/10.1038/ejhg.2011.160
Wuttig D, Zastrow S, Füssel S, Toma MI, Meinhardt M, Kalman K, Junker K, Sanjmyatav J, Boll K, Hackermüller J, Rolle A, Grimm MO, Wirth MP. CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases. Int J Cancer. 2011 Dec 31. DOI dx.doi.org/10.1002/ijc.27419 [Epub ahead of print]
zu Siederdissen CH, Bernhart SH, Stadler PF, Hofacker IL. A folding algorithm for extended RNA secondary structures. Bioinformatics. 27 (2011), 13, S. i129-36. DOI dx.doi.org/10.1093/bioinformatics/btr220

Publikationen 2010

Al-Robaiy S, Dihazi H, Kacza J, Seeger J, Schiller J, Huster D, Knauer J, Straubinger RK. Metamorphosis of Borrelia burgdorferi organisms – RNA, lipid and protein composition in context with the spirochetes’ shape. Journal of Basic Microbiology. 50 (2010), Sup. 1, S. 5–17.
Amemiya CT, Powers TP, Prohaska SJ, Grimwood J, Schmutz J, Dickson M, Miyake T, Schoenborn MA, Myers R, Ruddle FH, Stadler PF. Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome. Proceedings of the National Academy of Sciences of the United States of America. 107 (2010), 8, S. 3622–3627.
Arnold C, Stadler PF. Polynomial algorithms for the Maximal Pairing Problem: efficient phylogenetic targeting on arbitrary trees. Algorithms for molecular biology. 5 (2010), 25, 10 S. DOI dx.doi.org/10.1186/1748-7188-5-25
Bermudez-Santana C, Attolini CSO, Kirsten T, Engelhardt J, Prohaska SJ, Steigele S, Stadler PF. Genomic organization of eukaryotic tRNAs. BMC genomics. 11 (2010), 270, 14 S. DOI dx.doi.org/10.1186/1471-2164-11-270
Boria I, Gruber A, Tanzer A, Bernhart SH, Lorenz R, Müller MM, Hofacker IL, Stadler PF. Nematode sbRNAs: homologs of vertebrate Y RNAs. Journal of molecular evolution. 70 (2010), 4, S. 346–358.
Chung NP, Breun SK, Bashirova A, Baumann JG, Martin TD, Karamchandani JM, Rausch JW, Le Grice SF, Wu L, Carrington M, Kewalramani VN. HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN). J Biol Chem. 285 (2010), 3, S. 2100–2112.
Dienelt A, zur Nieden NI. Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation. Stem Cells Dev. 2010 Nov 30 [Epub ahead of print]. DOI dx.doi.org/10.1089/scd.2010.025
Fasold M, Stadler PF, Binder H. G-stack modulated probe intensities on expression arrays – sequence corrections and signal calibration. BMC bioinformatics. 11 (2010), 207, 24 S. DOI dx.doi.org/10.1186/1471-2105-11-207
Findeiß S, Schmidtke C, Stadler PF, Bonas U. A novel family of plasmid-transferred anti-sense ncRNAs. RNA biology. 7 (2010), 2, S. 120–124. DOI dx.doi.org/10.4161/rna.7.2.11184
Fricke S, Fricke C, Oelkrug C, Hilger N, Schönfelder U, Kamprad M, Lehmann J, Boltze J, Emmrich F, Sack U. Characterization of murine non-adherent bone marrow cells leading to recovery of endogenous hematopoiesis. Cell Mol Life Sci. 67 (2010), 23, S. 4095–4106.
Fricke S, Fricke C, Schimmelpfennig C, Oelkrug C, Schönfelder U, Blatz R, Zilch C, Faber S, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR assay for the differentiation of Candida species. J Appl Microbiol. 109 (2010), 4, S 1150–1158.
Gessner C, Rechner B, Hammerschmidt S, Kuhn H, Hoheisel G, Sack U, Ruschpler P, Wirtz H. Angiogenic markers in breath condensate identify non-small cell lung cancer. Lung Cancer, 68 (2010), 2, S. 177–184.
Hemdan NY, Birkenmeier G, Wichmann G, Abu El-Saad A, Krieger T, Conrad K, Sack U. Interleukin-17-producing T helper cells in autoimmunity. Autoimmunity Reviews, 9 (2010), 11, S. 785–792.
Hinz D, Simon JC, Maier-Simon C, Milkova L, Röder S, Sack U, Borte M, Lehmann I, Herberth G. Reduced maternal regulatory T cell numbers and increased T helper type 2 cytokine production are associated with elevated levels of immunoglobulin E in cord blood. Clinical and Experimental Allergy. 40 (2010), 3, S. 419–426.
Hofacker I, Flamm C, Heine C, Wolfinger MT, Scheuermann G, Stadler PF. BarMap: RNA folding on dynamic energy landscapes, RNA. 16 (2010), 7, S. 1308–1316.
Huang FWD, Qin J, Reidys CM, Stadler PF. Target prediction and a statistical sampling algorithm for RNA-RNA interaction. Bioinformatics. 26 (2010), 2, S. 175–181.
Kranz A, Wagner DC, Kamprad M, Scholz M, Schmidt UR, Nitzsche F, Aberman Z, Emmrich F, Riegelsberger UM, Boltze J. Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats. Brain Res, 1315 (2010), S. 128–36.
Lehmann J, Stadler PF, Eisenhardt C, Krauss V. Some novel intron positions in conserved Drosophila genes are caused by intron sliding or tandem duplication. BMC evolutionary biology. 10 (2010), 156, 15 S. DOI dx.doi.org/10.1186/1471-2148-10-156
Lenz D, Barten MJ, Hiller S, Tarnok A, Sack U. Regenerative and predictive medicine of cardiovascular disease: the 9th Leipziger Workshop and the 2nd International Workshop on slide based cytometry. Cytom Part A, 64 (2005), 2, S. 110-114.
Lindner I. et al. alpha 2-Macroglobulin Inhibits the Malignant Properties of Astrocytoma Cells by Impeding beta-Catenin Signaling. Cancer Research, v. 70 (2010), no. 1, p. 277–287.
Marz M, Vanzo N, Stadler PF. Temperature-dependent structural variability of RNAs: spliced leader RNAs and their evolutionary history. Journal of bioinformatics and computational biology. 8 (2010), 1, S. 1–17.
Mühle A, Mühle C, Amann K, Dötsch J, Nüsken KD, Boltze J, Schneider H. No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers. Pediatr Nephrol. 25 (2010), 9, S. 1653–61.
Müller M, Lutter D, Püschel AW. Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. J Cell Sci. 123 (2010), Pt 2, S. 286–94.
Perseke M, Bernhard D, Fritzsch G, Brümmer F, Stadler PF, Schlegel M. Mitochondrial genome evolution in Ophiuroidea, Echinoidea, and Holothuroidea: insights in phylogenetic relationships of Echinodermata. Molecular phylogenetics and evolution. 56 (2010), 1, S. 201–211.
Prohaska SJ, Stadler PF, Krakauer DC. Innovation in gene regulation: the case of chromatin computation. Journal of theoretical biology. 265 (2010), 1, S. 27–44.
Riester M, Stadler PF, Klemm K. Reconstruction of pedigrees in clonal plant populations. Theoretical population biology. 78 (2010), 2, S. 109–117.
Rupf S, Lehmann A, Hannig M, Schafer B, Schubert A, Feldmann U, Schindler A. Killing of adherent microbes by a non-thermal atmospheric plasma jet. J Med Microbiol. 59 (2010), Pt 2, S. 206–12.
Schneeweiss A, Buyens K, Giese M, Sanders N, Ulbert S. Synergistic effects between natural histone mixtures and polyethylenimine in non-viral gene delivery in vitro. Int J Pharm. 400 (2010), 1–2, S. 86–95.
Sharma C, Hoffmann S, Darfeuille F, Reignier J, Findeiß S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J. The primary transcriptome of the major human pathogen Helicobacter pylori. Nature. 464 (2010), 7286, S. 250–255.
Stadler BM, Stadler PF. Combinatorial vector fields and the valley structure of fitness landscapes. Journal of mathematical biology. 61 (2010), 6, S. 877–898.
Stolzing A, Sellers D, Llewelyn O, Scutt A. Diabetes induced changes in rat mesenchymal stem cells. Cells Tissues Organs. 191 (2010), 6, S. 453–65.
Tafer H, Kehr S, Hertel J, Hofacker IL, Stadler PF. RNAsnoop : efficient target prediction for H/ACA snoRNAs. Bioinformatics. 26 (2010), 5, S. 610–616.
Taiani JT, Krawetz RJ, zur Nieden NI, Wu YE, Kallos MS, Matyas JR, Rancourt DE. Reduced Differentiation Efficiency of Murine Embryonic Stem Cells in Stirred Suspension Bioreactors. Stem Cell Dev. (2010), 7, S. 989–998.
Tessema B, Biadglegne F, Mulu A, Getachew A, Emmrich F, Sack U. Magnitude and determinants of nonadherence and nonreadiness to highly active antiretroviral therapy among people living with HIV/AIDS in Northwest Ethiopia: a cross-sectional study. AIDS research and therapy, 7 (2010), 2, 8 S. DOI dx.doi.org/10.1186/1742-6405-7-2
Tessema B, Yismaw G, Kassu A, Amsalu A, Mulu A, Emmrich F, Sack U. Seroprevalence of HIV, HBV, HCV and syphilis infections among blood donors at Gondar University Teaching Hospital, Northwest Ethiopia: declining trends over a period of five years. BMC Infectious Diseases, 10 (2010), 111, 7 S. DOI dx.doi.org/10.1186/1471-2334-10-111
Yerebakan C, Klopsch C, Niefeldt S, Zeisig V, Vollmar B, Liebold A, Sandica E, Steinhoff G. Acute and chronic response of the right ventricle to surgically induced pressure and volume overload – an analysis of pressure-volume relations. Interact Cardiovasc Thorac Surg. 10 (2010), 4, S. 519–25.
Yerebakan C, Sandica E, Prietz S, Klopsch C, Ugurlucan M, Kaminski A, Abdija S, Lorenzen B, Boltze J, Nitzsche B, Egger D, Barten M, Furlani D, Ma N, Vollmar B, Liebold A, Steinhoff G. Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload. Cell Transplant, 18 (2009), 8, S. 855-68.
zur Nieden NI, Baumgartner L. Assessing developmental osteotoxicity of chlorides in the embryonic stem cell test. Reprod Toxicol. 30 (2010), 2, S. 277–283.
zur Nieden NI, Davis LA, Rancourt DE. Comparing three novel endpoints for developmental osteotoxicity in the embryonic stem cell test. Toxicol Appl Pharmacol. 247 (2010), 2, S. 91–97.
zur Nieden NI, Davis LA, Rancourt DE. Monolayer cultivation of osteoprogenitors shortens duration of the embryonic stem cell test while reliably predicting developmental osteotoxicity. Toxicology.277 (2010), 1–3, S. 66–73.

Publikationen 2009

Althues H, Pötschke P, Kim G M, Kaskel S. Structure and Mechanical Properties of Transparent ZnO/PBDMA Nanocomposites. J Nanosci Nanotechno, 9 (2009), 4, S. 2739-2745.
Aupperle H, Thielebein J, Kiefer B, März I, Dinges G, Schoon HA, Schubert A. Expression of genes encoding matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in normal and diseased canine mitral valves. J Comp Pathol, 140 (2009), 4, S. 271-277.
Borte S, Liebert UG, Borte M, Sack U. Efficacy of measles, mumps and rubella revaccination in children with juvenile idiopathic arthritis treated with methotrexate and etanercept. Rheumatology, 48 (2009), 2, S. 144-148.
Borte S, Pan-Hammarstrom Q, Liu C, Sack U, Borte M, Wagner U, Graf D, Hammarström L. Interleukin-21 restores immunoglobulin production ex vivo in patients with common variable immunodeficiency and selective IgA deficiency. Blood, 114 (2009), 19, S. 4089-4098.
Burkhardt J, Petit-Teixeira E, Teixeira VH, Kirsten H, Garnier S, Ruehle S, Oeser C, Wolfram G, Scholz M, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Pascual-Salcedo D, Bombardieri S, Dequeker J, Radstake TR, Van Riel P, van de Putte L, Bardin T, Prum B, Buchegger-Podbielski U, Emmrich F, Melchers I, Cornelis F, Ahnert P. Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis. J Rheumatol, 36 (2009), 10, S.2149-2157.
Conant G, Stadler PF. Solvent exposure imparts similar selective pressures across a range of yeast proteins. Mol Biol Evol, 26 (2009), 5, S. 1155-1161.
Fisher M, Feuerstein G, Howells DW, Hurn PD, Kent TA, Savitz SI, Lo EH; STAIR Group. Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke, 40 (2009), 6, S. 2244-2250.
Fricke S, Ackermann M, Stolzing A, Schimmelpfennig C, Hilger N, Jahns J, Hildebrandt G, Emmrich F, Ruschpler P, Pösel C, Kamprad M, Sack U. Allogeneic non-adherent bone marrow cells facilitate hematopoietic recovery but do not lead to allogeneic engraftment. PLoS One (2009), Jul 7, 4(7), e6157.
Fricke S, Fricke C, Schimmelpfennig C, Oelkrug C, Schönfelder U, Blatz R, Faber S, Zilch C, Hilger N, Ruhnke M, Rodloff A. New Real-time PCR assay for the differentiation of Candida species. Appl Microbiol (2009) (accepted JAM-2009-2135).
Härtig W, Reichenbach A, Voigt C, Boltze J, Bulavina L, Schuhmann MU, Seeger J, Schusser GF, Freytag C, Grosche J. Triple fluorescence labelling of neuronal, glial and vascular markers revealing pathological alterations in various animal models. J Chem Neuroanat, 37 (2009), 2, S. 128-138.
Heinrich A, Riethmüller D, Gloger M, Schusser GF, Giese M, Ulbert S. RNA interference protects horse cells in vitro from infection with Equine Arteritis Virus. Antivir Res, 81 (2009), 3, S. 209-216.
Heintz D, Gallien S, Wischgoll S, Ullmann AK, Schaeffer C, Kretzschmar AK, van Dorsselaer A, Boll M. Differential membrane proteome analysis reveals novel proteins involved in the degradation of aromatic compounds in Geobacter metallireducens. Mol Cell Proteomics, 8 (2009), 9, S. 2159-2169.
Hellmuth M, Imrich W, Klöckl W, Stadler PF. Approximate graph products. Eur J Combin, 30 (2009), 5, S. 1119-1133.
Herberth G, Gubelt R, Röder S, Krämer U, Schins RP, Diez U, Borte M, Heinrich J, Wichmann HE, Herbarth O, Lehmann I, LISA plus study group. Increase of inflammatory markers after indoor renovation activities: the LISA birth cohort study. Pediatr Allergy Immu, 20 (2009), 6, S. 563-570.
Hertel J, De Jong D, Marz M, Rose D, Tafer H, Tanzer A, Schierwater B, Stadler PF. Non-coding RNA annotation of the genome of Trichoplax adhaerens. Nucleic Acids Res, 37 (2009), 5, S. 1602-1615.
Hoffmann S, Otto C, Kurtz S, Sharma CM, Khaitovich P, Vogel J, Stadler PF, Hackermüller J. Fast Mapping of Short Sequences with Mismatches, Insertions and Deletions Using Index Structures. PLoS Comput Biol, 5 (2009), 5(9), e1000502.
Jaen O, Petit-Teixeira E, Kirsten H, Ahnert P, Semerano L, Pierlot C, Cornelis F, Boissier MC, Falgarone G; European Consortium on Rheumatoid Arthritis Families. No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis. Arthritis Res Ther. 2009;11(1):R5. Epub 2009 Jan 13.
Kaczkowski B, Torarinsson E, Reiche K, Havgaard JH, Stadler PF, Gorodkin J. Structural profiles of human miRNA families from pairwise clustering. Bioinformatics, 25 (2009), 3, S. 291-294.
Kirsten H, Burkhardt J, Hantmann H, Hunzelmann N, Vaith P, Ahnert P, Melchers I. 5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population. Arthritis Res Ther, 11 (2009), 2, S. 403.
Kirsten H, Petit-Teixeira E, Hantmann H, Reichardt J, Burkhardt J, Emmrich F, Cornelis F, Ahnert P. A family-based study does not support the association of a functional polymorphism in the gene for endothelial nitric oxide synthase with risk for rheumatoid arthritis. Scand J Rheumatol, 38 (2009), 4, S. 320-321.
Kirsten H, Petit-Teixeira E, Scholz M, Hasenclever D, Hantmann H, Heider D, Wagner U, Sack U, Hugo Teixeira V, Prum B, Burkhardt J, Pierlot C, Emmrich F, Cornelis F, Ahnert P. Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study. Arthritis Res Ther, 11 (2009), 3, R60.
Krämer U, Sugiri D, Ranft U, Krutmann J, von Berg A, Berdel D, Behrendt H, Kuhlbusch T, Hochadel M, Wichmann HE, Heinrich J, GINIplus and LISAplus study groups. Eczema, respiratory allergies, and traffic-related air pollution in birth cohorts from small-town areas. J Dermatol Sci, 56 (2009), 2, S. 99-105.
Krupka I, Knauer J, Lorentzen L, O‘Connor TP, Saucier J, Straubinger RK. Borrelia burgdorferi sensu lato species in Europe induce diverse immune responses against C6 peptides in infected mice. Clin Vaccine Immunol, 16 (2009), 11, S. 1546-1562.
Lee SM, Grass G, Kim G M, Dresbach C, Zhang L, Gösele U, Knez M. Low-temperature ZnO atomic layer deposition on biotemplates: flexible photocatalytic ZnO structures from Eggshell Membranes. Phys Chem Chem Phys, 11 (2009), 19, S. 3608-3614.
Meier H, Bullinger J, Marx G, Deten A, Horn LC, Rassler B, Zimmer HG, Briest W. Crucial role of interleukin-6 in the development of norepinephrine-induced left ventricular remodeling in mice. Cell Physiol Biochem, 23 (2009), 3-4, S. 327-334.
Quintana L, zur Nieden NI, Semino CE. Morphogenetic and regulatory mechanisms during developmental chondrogenesis. Tissue Eng Pt B-Rev, 15 (2009), 1, S. 29-41.
Sack U, Conrad K, Csernok E, Frank I, Hiepe F, Krieger T, Kromminga A, Landenberg P, Messer G, Witte T, Mierau R, die deutsche EASI-Gruppe (European Autoimmunity Standardization Initiative). Autoantikörpernachweis mittels indirekter Immunfluoreszenz an HEp-2-Zellen. Deut Med Wochenschr, 134 (2009), 24, S. 1278-1282.
Sack U, Conrad K, Csernok E, Frank I, Hiepe F, Krieger T, Kromminga A, von Landenberg P, Messer G, Witte T, Mierau R, German EASI (European Autoimmunity Standardization Initiative). Autoantibody detection using indirect immunofluorescence on HEp-2 cells. Ann NY Acad Sci, 1173 (2009), S. 166-73.
Saver JL, Albers GW, Dunn B, Johnston KC, Fisher M, STAIR VI Consortium. Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials. Stroke, 40 (2009), 7, S. 2594-2600.
Scheibye-Alsing K, Hoffmann S, Frankel A, Jensen P, Stadler PF, Mang Y, Tommerup N, Gilchrist MJ, Nygard AB, Cirera S, Jorgensen CB, Fredholm M, Gorodkin J. Sequence assembly: review. Comput Biol Chem, 33 (2009), 2, S. 121-136.
Schlomann U, Schwamborn JC, Müller M, Fässler R, Püschel AW. The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase. J Cell Sci. 2009 Jun 15;122(Pt 12):2034-42. Epub 2009 May 19.
Scholz M, Ackermann M, Emmrich F, Loeffler M, Kamprad M. Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastin schedules in a chemotherapy mouse model. Biologics 3 (2009), S. 27-37.
Scholz M, Kamprad M, Ackermann M, Löffler M, Emmrich F, Engel Ch. A Pharmacokinetic Model of Filgrastim and Pegfilgrastim application in Normal and Cyclophosphamide Induced Granulopenic Mice. Cell Proliferat 42 (2009), 6, S. 813-22.
Simon P, Burkhardt U, Sack U, Kaisers UX, Muensterer OJ. Inflammatory Response Is No Different in Children Randomized to Laparoscopic or Open Appendectomy. J Laparoendosc Adv A, 19 (2009), Suppl 1, S. S71-S76.
Sommer G, Kralisch S, Stangl V, Vietzke A, Köhler U, Stepan H, Faber R, Schubert A, Lössner U, Bluher M, Stumvoll M, Fasshauer M. Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells. J Cell Biochem, 106 (2009), 4, S. 729-37.
Stadler PF, Chen JJ, Hackermüller J, Hoffmann S, Horn F, Khaitovich P, Kretzschmar AK, Mosig A, Prohaska SJ, Qi X, Schutt K, Ullmann K. Evolution of vault RNAs. Mol Biol Evol, 26 (2009), 9, S. 1975-91.
Stroh A, Boltze J, Sieland K, Hild K, Gutzeit C, Jung T, Kressel J, Hau S, Reich D, Grune T, Zimmer C. Impact of magnetic labeling on human and mouse stem cells and their long-term magnetic resonance tracking in a rat model of Parkinson disease. Mol Imaging, 8 (2009), 3, S. 166-78.
Tessema B, Muche A, Bekele A, Reissig D, Emmrich F, Sack U. Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia. A five - year retrospective study. BMC Public Health, 4 (2009), 371.
Wechsler L, Steindler D, Borlongan C, Chopp M, Savitz S, Deans R, Caplan L, Hess D, Mays RW, Boltze J, Boncoraglio G, Borlongan CV, Caplan LR, Carmichael ST, Chopp M, Davidoff AW, Deans RJ, Fisher M, Hess DC, Kondziolka D, Mays RW, Norrving B, Parati E, Parent J, Reynolds BA, Gonzalez-Rothi LJ, Savitz S, Sanberg P, Schneider D, Sinden JD, Snyder E, Steinberg GK, Steindler D, Wechsler L, Weiss MD, Weiss S, Victor S, Zheng T. Stem Cell Therapies as an Emerging Paradigm in Stroke Participants. Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke. Stroke, 40 (2009), 2, S. 510-5.
Wilcke A, Weissfuss J, Kirsten H, Wolfram G, Boltze J,Ahnert P. The role of gene DCDC2 in German dyslexics. Ann Dyslexia, 59 (2009), 1, S. 1-11.
Yerebakan C, Klopsch C, Prietz S, Boltze J, Vollmar B, Liebold A, Steinhoff G, Sandica E. Pressure-volume loops: feasible for the evaluation of right ventricular function in an experimental model of acute pulmonary regurgitation? Interact Cardiovasc Thorac Surg, 9 (2009), 2, S. 163-8.
Yerebakan C, Sandica E, Prietz S, Klopsch C, Ugurlucan M, Kaminski A, Abdija S, Lorenzen B, Boltze J, Nitzsche B, Egger D, Barten M, Furlani D, Ma N, Vollmar B, Liebold A, Steinhoff G. Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload. Cell Transplant, 18 (2009), 8, S. 855-68.

Publikationen 2008

Amemiya CT, Prohaska SJ, Hill-Force A, Cook A, Wasserscheid J, Ferrier DEK, Pascual-Anaya J, Garcia-Fernandez J, Dewar K, Stadler PF. The amphioxus Hox cluster: Characterization, comparative genomics, and evolution. J Exp Zool Part B 310B (2008), 5, S. 465-477.
Aupperle H, März I, Schubert A, Dinges G, Thielebein J, Schoon HA. Störungen des Metabolismus der extrazellularmatrix des Herzens bei der kaninen idiopathischen dilatativen Kardiomyopathie. Der praktische Tierarzt 89 (2008), 12, S. 998-1005.
Bernhart SH, Hofacker IL, Will S, Gruber AR, Stadler PF. RNAalifold. Improved consensus structure prediction for RNA alignments. BMC Bioinformatics. Online journal 9 (2008), Art. 474, 13S.
Bockamp E, Sprengel R, Eshkind L, Lehmann T, Braun JM, Emmrich F, Hengstler JG. Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration. Regen Med 3 (2008), 2, S. 217-35.
Bold A, Wurth R, Keller T, Trahorsch T, Voigt P, Schubert S, Sack U. Low-cost enumeration of CD4+ T cells using a density-based negative selection method (RosettaSepTM) for the monitoring of HIV-infected individuals in non-OECD countries. Cytom Part A 73 (2008), 1, S. 28-35.
Boltze J, Förschler A, Nitzsche B, Waldmin D, Hoffmann A, Boltze CM, Oreyer AY, Goldammer A, Reischauer A, Härtig W, Geiger KD, Barthel H, Emmrich F, Gille U. Permanent middle cerebral artery occlusion in sheep: a novel large animal model of focal cerebral ischemia. J Cerebr Blood F Met 28 (2008), 12, 1951-64.
Cepok S, Hoffmann S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wasmuth R, Hemmer B. HLA-DRB1 0401 and HLA-DRB1 0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis. J Neuroimmunol 203 (2008), 2, S. 194.
Daegelmann C, Herberth G, Röder S, Herbarth O, Giese T, Krämer U, Behrendt H, Borte M, Heinrich J, Emmrich F, Lehmann I; LISAplus study group. Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children. Clin Exp Allergy 38 (2008), 3, S. 438-48.
Davis LA, zur Nieden NI. Mesodermal fate decisions of a stem cell: the Wnt switch. Cell Mol Life Sci 65 (2008), 17, S. 2658-2674.
Dress AWM, Flamm C, Fritzsch G, Grünewald S, Kruspe M, Prohaska SJ, Stadler PF. Noisy: Identification of problematic columns in multiple sequence alignments. Algorithm Mol Biol. Online journal 3 (2008), Art. 7, 10S.
Focke A, Schwarz S, Foerschler A, Scheibe J, Milosevic J, Zimmer C, Schwarz J. Labeling of human neural precursor cells using ferromagnetic nanoparticles. Magn Reson Med. 2008 Dec;60(6):1321-8.
Geis M, Flamm C, Wolfinger MT, Tanzer A, Hofacker IL, Middendorf M, Mandl C, Stadler PF, Thurner C. Folding kinetics of large RNAs. J Mol Biol 379 (2008), 1, S. 160-173.
Gessner C, Dihazi H, Brettschneider S, Hammerschmidt S, Kuhn H, Eschrich K, Keller T, Engelmann L, Sack U, Wirtz H. Presence of cytokeratins in exhaled breath condensate of mechanical ventilated patients. Resp Med 102 (2008), 2, S. 299-306.
Goettsch W, Schubert A, Morawietz H. Expression of human endothelinconverting enzyme isoforms: role of angiotensin II. Can J Physiol Pharm 86 (2008), 6, S. 299-309.
Gruber AR, Kilgus C, Mosig A, Hofacker IL, Hennig W, Stadler PF. Arthropod 7SK RNA. Mol Biol Evol 25 (2008), 9, S. 1923-1930.
Hau S, Reich DM, Scholz M, Naumann W, Emmrich F, Kamprad M, Boltze, J. Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro. BMC Neurosci (2008), 9, S. 30.
Haussig S, Schubert A, Mohr FW, Dhein S. Sub-chronic nicotine exposure induces intercellular communication failure and differential down-regulation of connexins in cultured human endothelial cells. Atherosclerosis 196 (2008), 1, S. 210-8.
Hemdan NY. The role of interleukin-12 in the heavy metal-elicited immunomodulation: relevance of various evaluation methods. J Occup Med Toxicol 3 (2008), Art 25, 14S.
Hertel J, Hofacker IL, Stadler PF. SnoReport: Computational identification of snoRNAs with unknown targets. Bioinformatics 24 (2008), 2, S. 158-164.
Hoffmann S, Cepok S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wassmuth R, Hemmer B. HLA-DRB1*0401 and HLADRB1* 0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis. Am J Hum Genet 83 (2008), 2, S. 219-27.
Hollenbach M, Hintersdorf A, Huse K, Sack U, Bigl M, Groth M, Santel T, Buchold M, Lindner I, Otto A, Sicker D, Schellenberger D, Almendinger J, Pustowoit B, Birkemeyer C, Platzer M, Oerlecke I, Hemdan NY, Birkenmeier G. Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors. Biochem Pharmacol 76 (2008), 5, S. 631-644.
Hoppe A, Kamprad M, Wegmann C, Wötzel M, Hauss J, Emmrich F, Fangmann J, Sack U. Natürliche Killerzellen und natürliche Killer-T-Zellen bei Nierentransplantation. Laboratoriumsmedizin 32 (2008), 3, S. 140-147.
Jochl C, Rederstorff M, Hertel J, Stadler PF, Hofacker IL, Schrettl M, Haas H, Hüttenhofer A. Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis. Nucleic Acids Res 36 (2008), 8, S. 2677-2689.
Jung C, Stöckle C, Wiesmüller KH, Laub R, Emmrich F, Jung G, Melms A. Complementary strategies to elucidate T helper cell epitopes in myasthenia gravis. J Neuroimmunol 201/202 (2008), S. 41-49.
Kendziorra K, Barthel H, Erbs S, Emmrich F, Hambrecht R, Schuler G, Sabri O, Kluge R. Effect of Progenitor Cells on Myocardial Perfusion and Metabolism in Patients After Recanalization of a Chronically Occluded Coronary Artery. J Nucl Med 48 (2008), 4, S. 557-563.
Kirsten H, Blume M, Emmrich F, Hunzelmann N, Mierau R, Rzepka R, Vaith P, Witte T, Melchers I, Ahnert P. No association between Systemic Sclerosis and the C77G Polymorphism in the Human PTPRC (CD45) Gene. J Rheumatol 35 (2008), 9, S. 1817-1819.
Klemm K, Flamm C, Stadler PF. Funnels in energy landscapes. Eur Phys J B 63 (2008), 3, S. 387-391.
Kralisch S, Sommer G, Stangl V, Köhler U, Kratzsch J, Stepan H, Faber R, Schubert A, Lössner U, Vietzke A, Bluher M, Stumvoll M, Fasshauer M. Secretory products from human adipocytes impair endothelial function via nuclear factor kappaB. Atherosclerosis 196 (2008), 2, S. 523-31.
Krauss V, Thummler C, Georgi F, Lehmann J, Stadler PF, Eisenhardt C. Near intron positions are reliable phylogenetic markers: An application to holometabolous insects. Mol Biol Evol 25 (2008), 5, S. 821-830.
Krupp W, Holland H, Koschny R, Bauer M, Schober R, Kirsten H, Livrea M, Meixensberger J, Ahnert P. Genome-wide genetic characterization of an atypical meningioma by single-nucleotide polymorphism array-based mapping and classical cytogenetics. Cancer Genet Cytogenet. 2008 Jul 15;184(2):87-93.
Kyaw WO, Uhlig A, Koller G, Sack U, Schusser GF. Freies Hämoglobin und Tumor-Nekrose-Faktor-Alpha im Blut von Pferden mit Kolik oder akuter Kolitis. Berl Munch Tierarztl W 121 (2008), 11-12, S. 440-445.
Lehmann J, Stadler PF, Prohaska SJ. SynBlast: Assisting the analysis of conserved synteny information. BMC Bioinformatics. Online journal 9 (2008), Art. 351, 14S.
Marz M, Kirsten T, Stadler PF. Evolution of spliceosomal snRNA genes in metazoan animals. J Mol Evol 67 (2008), 6, S. 594-607.
Morgenstern V, Zutavern A, Cyrys J, Brockow I, Koletzko S, Krämer U, Behrendt H, Herbarth O, von Berg A, Bauer CP, Wichmann HE, Heinrich J; GINI Study Group; LISA Study Group. Atopic diseases, allergic sensitization, and exposure to trafficrelated air pollution in children. Am J Resp Crit Care M 177 (2008), 12, S. 1331-1337.
Perseke M, Fritzsch G, Ramsch K, Bernt M, Merkle D, Middendorf M, Bernhard D, Stadler PF, Schlegel M. Evolution of mitochondrial gene orders in echinoderms. Mol Phylogenet Evol 47 (2008), 2, S. 855-864.
Pfefferkorn P, Scholz U, Veneruso V, Nikolaus T, Madin K, Eichenlaub U, Schubert A, Lehmann J. Influence of Serum Deprivation on Adherence and Proliferation of Murine Mesenchymal Progenitor Cells Analysed with Roche´s xCELLigence System. Biochemica (2008), 4, S. 14-16.
Pierzchalski A, Robitzki A, Mittag A, Emmrich F, Sack U, O‘Connor JE, Bocsi J, Tarnok A. Cytomics and nanobioengineering. Cytom Part B-Clin Cy 74 (2008), 6, S. 416-426.
Reich DM, Hau S, Stahl T, Scholz M, Naumann W, Emmrich F, Boltze J, Kamprad M. Neuronal hypoxia in vitro: investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells. BMC Neurosci (2008), 9, S. 91.
Rose D, Hertel J, Reiche K, Stadler PF, Hackermüller J. NcDNAlign: plausible multiple alignments of non-proteincoding genomic sequences. Genomics 92 (2008), 1, S. 65-74.
Rose D, Jöris J, Hackermüller J, Reiche K, Li Q, Stadler PF. Duplicated RNA genes in teleost fish genomes. J Bioinform Comput Biol 6 (2008), 6, 1157-75.
Sack U, Emmrich F. Monoklonale Antikörper: Prinzipien, Herstellung, Anwendung und Nebenwirkungen. Internist 49 (2008), 8, S. 921-928.
Santel T, Pflug G, Hemdan NY, Schafer A, Hollenbach M, Buchold M, Hintersdorf A, Lindner I, Otto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebhardt R, Platzer M, Weiss T, Vijayalakshmi MA, Kruger M, Birkenmeier G. Curcumin inhibits glyoxalase 1: a possible link to its antiinflammatory and anti-tumor activity. PLoS ONE (2008), 3, S. e3508.
Schimmelpfennig C. Biolumineszenz- und Fluoreszenz-Imaging: Ein neues Verfahren zur nicht-invasiven Bildgebung von zellbiologischen Prozessen in Kleintieren. Ingenieur Nachrichten (2008), 2, S. 10.
Schimmelpfennig C, Schmiedeknecht A, Emmrich F. Visualisierung von Immunfunktionen mithilfe von Biolumineszenz Imaging. Biospektrum 14 (2008), 5, S. 481-482.
Schoefer Y, Zutavern A, Brockow I, Schäfer T, Krämer U, Schaaf B, Herbarth O, von Berg A, Wichmann HE, Heinrich J; LISA study group. Health risks of early swimming pool attendance. Int J Hyg Envir Heal 211 (2008), 3-4, S. 367-73.
Schulz SM, Köhler G, Schütze N, Knauer J, Straubinger RK, Chackerian AA, Witte E, Wolk K, Sabat R, Iwakura Y, Hölscher C, Müller U, Kastelein RA, Alber G. Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is asso ciated with IL-23-dependent IL-22, but not IL-17. J Immunol 181 (2008), 11, S. 7891-901.
Sonnleitner E, Sorger-Domenigg T, Madej MJ, Findeiss S, Hackermüller J, Hüttenhofer A, Stadler PF, Bläsi U, Moll I. Detection of small RNAs in Pseudomonas aeruginosa by RNomics and structure-based bioinformatic tools. Microbiology 154 (2008), 10, S. 3175-87.
Stolzing A, Jones E, McGonagle D, Scutt A. Age related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies. Mech Ageing Dev, 129 (2008), 3, S. 163-173.
Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, Lehmann J, Sack U. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytom Part A 73 (2008), 3, S. 351-360.
Trepnau D, Ulrich E, Uhlig R, Lindner T, Selbitz HJ, Rösler U, Gabert J, Bergfeld U, Fehlhaber K, Brabetz W, Lehmann J. Antikörperantwort nach Impfung von Mastschweinen mit einem Salmonella-Typhimurium-Lebendimpfstoff in Abhängigkeit von der Applikationsform. Berl Munch Tierarztl 121 (2008), 9-10, S. 334-340.
Ueberham E, Lindner R, Kamprad M, Hiemann R, Hilger N, Woithe B, Mahn D, Cross M, Sack U, Gebhardt R, Arendt T, Ueberham U. Oval cell proliferation in p16INK4a expressing mouse liver is triggered by chronic growth stimuli. J Cell Mol Med 12 (2008), 2, S. 622-638.
Weimann A, Eisele RM, Pawellek S, Hippler-Benscheid M, Rüggeberg A, Cammann H, Radke C, Müller C, Klupp J, Sack U, Lun A. Diagnostic value of peripheral blood markers for acute rejection in LTX-patients receiving anti IL-2R antibodies. Laboratoriumsmedizin 32 (2008), 3, S. 148-157.
Willms H, Wiechmann V, Sack U, Gillissen A. Tracheobronchopathia osteochondroplastica: A rare cause of chronic cough with haemoptysis. Cough 4 (2008), 4, 4S.
Zutavern A, Brockow I, Schaaf B, von Berg A, Diez U, Borte M, Kraemer U, Herbarth O, Behrendt H, Wichmann HE, Heinrich J; LISA Study Group. Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA. Pediatrics (2008), 121, S. e44-52.

Publikationen 2007

Ahnert P, Kirsten H. Association of ITGAV supports a role of angiogenesis in rheumatoid arthritis. Arthritis Res Ther. 2007;9(5):108.
Athanasius F, Bompfünewerer Consortium, Backofen R, Bernhart SH, Flamm C, Fried C, Fritzsch G, Hackermüller J, Hertel J, Hofacker IL, Missal K, Mosig A, Prohaska SJ, Rose D, Stadler PF, Tanzer A, Washietl S, Will S. RNAs everywhere: genome-wide annotation of structured RNAs. J Exp Zool Part B (2007), 308, S. 1-25.
Aupperle H, Garbade J, Schubert A, Barten M, Dhein S, Schoon HA, Mohr FW. Effects of autologous stem cells on immunohistochemical patterns and gene expression of metalloproteinases and their tissue inhibitors in doxorubicin cardiomyopathy in a rabbit model. Vet Pathol 44 (2007), 4, S. 494-503.
Averbeck M, Gebhardt C, Emmrich F, Treudler R, Simon JC. Immunologic principles of allergic disease. J Dtsch Dermatol Ges 5 (2007), 11, S. 1015-28.
Backofen R, Flamm C, Fried C, Fritzsch G, Hackermüller J, Hertel J, Hofacker IL, Missal K, Prohaska SJ, Mosig A, Rose D, Stadler PF, Tanzer A, Washietl S, Will S. RNAs everywhere: genome-wide annotation of structured RNAs. J Exp Zool Part B, 308B (2007), 1, S. 1-25.
Bernt M, Merkle D, Ramsch K, Fritzsch G, Perseke M, Bernhard D, Schlegel M, Stadler PF, Middendorf M. CREx: inferring genomic rearrangements based on common intervals. Bioinformatics 23 (2007), 21, S. 2957-2958.
Brulport M, Schormann W, Bauer A, Hermes M, Elsner C, Hammersen FJ, Beerheide W, Spitkovsky D, Hartig W, Nussler A, Horn LC, Edelmann J, Pelz-Ackermann O, Petersen J, Kamprad M, von Mach M, Lupp A, Zulewski H, Hengstler JG. Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers. Hepatology 46 (2007), 3, S. 861-870.
Brumme S, Arnold T, Sigmarsson H, Lehmann J, Scholz HC, Hardt WD, Hensel A, Truyen H, Roesler U. Impact of Salmonella Typhimurium DT104 Virulence Factors invC and sseD affecting the onset, clinical course, colonization patterns and immune response of porcine salmonellosis. Vet Microbiol, 124 (2007), 3-4, S. 274-285.
Emmrich, F. Regenerative Medicine Today. BioWorld EUROPE Special Edition 1 (2007), S. 2-4.
ENCODE Project Consortium. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007), 447, S. 799-816.
Fangmann J, Wegmann C, Hoppe A, Martin P, Sack U, Harms J, Faber S, Emmrich F. Characterization of dendritic cell subsets in patients undergoing renal transplantation. Transplant Proc 39 (2007), 10, S. 3101-3104.
Förschler A, Boltze J, Waldmin D, Gille U, Zimmer C. MRI of experimental focal cerebral ischemia in sheep. Rofo 179 (2007), 5, S. 516-24.
Gebauer CM, Lenk H, Friedrich W, Sack U, Schuster V. Severe clinical course of Wiskott-Aldrich-syndrome – clinical course, hematologic, immunologic and genetic findings. Kinder- und Jugendmedizin (2007), 7, S. 39-44.
Gessner C, Hammerschmidt S, Kuhn H, Hoheisel G, Gillissen A, Sack U, Wirtz H. Breath Condensate nitrite correlates with hyperinflation in chronic obstructive pulmonary disease. Resp Med 101 (2007), 11, S. 2271-2278.
Hackermüller J, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447 (2007), 7146, S. 799-816.
Hemdan NY, Emmrich F, Faber S, Lehmann J, Sack U. Alterations of Th1/Th2 reac tivity by heavy metals – Possible consequences include induction of autoimmune diseases. Ann NY Acad Sci (2007), 1109, S. 129-137.
Hemdan NY, Lehmann I, Wichmann G, Lehmann J, Emmrich F, Sack U. Immunomodulation by mercuric chloride in vitro: application of different cell activation pathways. Clin Exp Immunol 148 (2007), 2, S. 325-37.
Hiemann R, Hilger N, Michel J, Nitschke J, Bohm A, Anderer U, Weigert M, Sack U. Automatic analysis of immunofluorescence patterns of HEp-2 cells. Ann NY Acad Sci 1109 (2007), 1, S. 358-371.
Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Kirsten H, Ahnert P. Comprehensive cytogenetic characterization of an esthesioneuroblastoma. Cancer Genet Cytogenet. 2007 Mar;173(2):89-96.
Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Schober R, Kirsten H, Ganten TM, Ahnert P. Cytogenetic and molecular biological characterization of an adult medulloblastoma. Cancer Genet Cytogen 178 (2007), 2, S. 104-113.
Kaltenhäuser S, Pierer M, Arnold S, Kamprad M, Baerwald C, Hantzschel H, Wagner U. Anti-bodies against cyclic citrullinated peptide are associated with the DRB1 shared epitope and predict joint erosion in rheumatoid arthritis. Rheumatology 46 (2007), 1, S. 100-104.
Kamprad M, Kindler S, Schuetze N, Emmrich F. Flow cytometric immunophenotyping of umbilical cord and peripheral blood haematopoietic progenitor cells by different CD34 epitopes, CD133, P-glycoprotein expression and rhodamine-123 efflux. Transfus Med Hemoth 34 (2007), 3, S. 195-203.
Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, Stadler PF, Hertel J, Hackermüller J, Hofacker IL, Bell I, Cheung E, Drenkow J, Dumais E, Patel S, Helt G, Ganesh M, Ghosh S, Piccolboni A, Sementchenko V, Tammana H, Gingeras TR. RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science 316 (2007), 5830, S. 1484-1488.
Kirsten H, Teupser D, Weissfuss J, Wolfram G, Emmrich F, Ahnert P. Robustness of single-base extension against mismatches at the site of primer attachment in a clinical assay. J Mol Med 85 (2007), 4, S. 361-9.
Kruspe M, Stadler PF. Progressive multiple sequence alignments from triplets. BMC Bioinformatics. Online journal 8 (2007), S. 254.
Löffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermüller J, Kretzschmar AK, Burger R, Gramatzki M, Blumert C, Bauer K, Cvijic H, Ullmann AK, Stadler PF, Horn F. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110 (2007), 4, S. 1330-3.
Meng GL, zur Nieden NI, Liu SY, Cormier JT, Kallos MS, Rancourt DE. Properties of murine embryonic stem cells maintained on human foreskin fibroblasts without LIF. Mol Reprod Dev, 75 (2007), 4, S. 614-622.
Mosig A, Guofeng M, Stadler BMR, Stadler PF. Evolution of the vertebrate Y RNA cluster. Theor Biosci 126 (2007), 1, S. 9-14.
Rose D, Hackermüller J, Washietl S, Reiche K, Hertel J, Findeiß S, Stadler PF, Prohaska SJ. Computational RNomics of drosophilids. BMC Genomics. Online journal 8 (2007), Art. 406.
Saalbach A, Klein C, Sleeman J, Sack U, Kauer F, Gebhardt C, Averbeck M, Anderegg U, Simon JC. Dermal fibroblasts induce maturation of dendritic cells. J Immunol 178 (2007), 8, S. 4966-4974.
Sack U, Bocsi J, Tarnok A. Importance of cytometry for clinical diagnostics and therapy. Transfus Med Hemoth 34 (2007), 3, S. 153-154.
Sack U, Conrad K, Csernok E, Frank I, Haass M, Krieger T, Seyfarth M, Schlosser U, Schmidt R, Witte T. Standardization of autoimmune diagnostics in Germany: activities of the German group in the European Autoimmune Standardization Initiative. Ann NY Acad Sci (2007), 1109, S. 31-36.
Sack U, Gerling F, Tarnok A. Age-related lymphocyte subset changes in the peripheral blood of healthy children – A metastudy. Transfus Med Hemoth 34 (2007), 3, S. 176-181.
Savkovic V, Gantzer H, Reiser U, Selig L, Gaiser S, Sack U, Kloppel G, Mossner J, Keim V, Horn F, Bodeker H. Clusterin is protective in pancreatitis through anti-apoptotic and anti-inflammatory properties. Biochem Bioph Res Co 356 (2007), 2, S. 431-437.
Schloendorn J, Sethe S, Stolzing A. Cellular therapy using microglial cells. Rejuv Res 10 (2007), 1, S. 87-99.
Schmidt A, Haas SJ, Hildebrandt S, Scheibe J, Eckhoff B, Racek T, Kempermann G, Wree A, Pützer BM. Selective targeting of adenoviral vectors to neural precursor cells in the hippocampus of adult mice: new prospects for in situ gene therapy. Stem Cells. 2007 Nov;25(11):2910-8. Epub 2007 Jul 19.
Schwenk M, Sack U, Esser C, Klein R. Diagnostic relevance of the determination of lymphocyte subpopulations in environmental medicine. Int J Hyg Envir Heal 210 (2007), 2, S. 177-198.
Schwamborn JC, Müller M, Becker AH, Püschel AW. Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. EMBO J. 2007 Mar 7;26(5):1410-22. Epub 2007 Feb 22.
Sharma N, Kaur J, Xhu H, zur Nieden NI, Rancourt DE. Characterization of secretory leukocyte protease inhibitor (SLPI) as an inhibitor of implantation serine proteinase. Mol Reprod Dev, 75 (2007), 7, S. 1136-1142.
Stolzing A, Hescheler J, Sethe S. Fusion and regenerative therapies: is immortality really recessive? Rejuv Res 10 (2007), 4, S. 571-86.
Tanneberger K, Kirchberger J, Bar J, Schellenberger W, Rothemund S, Kamprad M, Otto H, Schoneberg T, Edelmann A. A novel form of 6-phosphofructokinase – Identification and functional relevance of a third type of subunit in pichia pastoris. J Biol Chem 282 (2007), 32, S. 23687-23697.
Washietl S, Pedersen JS, Korbel JO, Stocsits C, Gruber AR, Hackermüller J, Hertel J, Lindemeyer M, Reiche K, Tanzer A, Ucla C, Wyss C, Antonarakis SE, Denoeud F, Lagarde J, Drenkow J, Kapranov P, Gingeras TR, Guigó R, Snyder M, Gerstein MB, Reymond A, Hofacker IL, Stadler PF. Structured RNAs in the ENCODE selected regions of the human genome. Genome Res 17 (2007), 6, S. 852-64.
zur Nieden NI, Cormier JT, Rancourt DE, Kallos MS. Embryonic stem cells remain highly pluripotent following long term expansion as aggregates in suspension bioreactors. J Biotechnol 129 (2007), 3, S. 421-432.
zur Nieden NI, Price FD, Davis LA, Everitt R, Rancourt DE. Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for beta-catenin in osteogenic differentiation. Mol Endocrinol 21 (2007), 3, S. 674-685.

Publikationen 2005

Aust G, Kamprad M, Lamesch P, Schmücking E. CXCR6 within T-helper (Th) and T-cytotoxic (Tc) type 1 lymphocytes in Graves’ disease (GD). Eur J Endocrinol, 152 (2005), 4, S. 635-643.
Boltze J, Kowalski I, Geiger K, Reich D, Gunther A, Buhrle C, Egger D, Kamprad M, Emmrich F. Experimental treatment of stroke in spontaneously hypertensive rats by CD34+ and CD34-cord blood cells. Ger Med Sci, 3, Doc09 (2005), 20051110.
Burkhardt C, Müller M, Badde A, Garner CC, Gundelfinger ED, Püschel AW. Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif. FEBS Lett. 2005 Jul 4;579(17):3821-8.
Erbs S, Linke A, Adams V, Lenk K, Thiele H, Diederich KW, Emmrich F, Kluge R, Kendziorra K, Sabri O, Schuler G, Hambrecht R. Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study. Circ Res, 97 (2005), 8, S. 756-762.
Garbade J, Schubert A, Rastan AJ, Lenz D, Walther T, Gummert JF, Dhein S, Mohr FW. Fusion of bone marrow-derived stem cells with cardiomyocytes in a heterologous in vitro model. Eur J Cardio-Thorac, 28 (2005), 5, S. 685-91.
Gessner C, Scheibe R, Wötzel M, Hammerschmidt S, Kuhn H, Engelmann L, Hoheisel G, Sack U. Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease. Resp Med, 99 (2005), 10, S. 1229-1240.
Gielen S, Adams V, Linke A, Erbs S, Mobius-Winkler S, Schubert A, Schuler G, Hambrecht R. Exercise training in chronic heart failure: correlation between reduced local inflammation and improved oxidative capacity in the skeletal muscle. Eur J Cardiov Prev R,12 (2005), 4, S. 393-400.
Hambrecht R, Schulze PC, Gielen S, Linke A, Mobius-Winkler S, Erbs S, Kratzsch J, Schubert A, Adams V, Schuler G. Effects of exercise training on insulin-like growth factor-I expression in the skeletal muscle of non-cachectic patients with chronic heart failure. Eur J Cardiov Prev R,12 (2005), 4, S. 401-6.
Hammerschmidt S, Kuhn H, Sack U, Schlenska A, Gessner C, Gillissen A, Wirtz H. Mechanical stretch alters alveolar type II cell mediator release toward a proinflammatory pattern. Am J Resp Cell Mol, 33 (2005), 2, S. 203-210.
Hemdan NY, Emmrich F, Adham K, Wichmann G, Lehmann I, El-Massry A, Ghoneim H, Lehmann J, Sack U. Dose-dependent modulation of the in vitro cytokine production of human immune competent cells by lead salts. Toxicol Sci, 86 (2005), 1, S. 75-83.
Holtick U, Vockerodt M, Pinkert D, Schoof N, Sturzenhofecker B, Kussebi N, Lauber K, Wesselborg S, Löffler D, Horn F, Trümper L, Kube D. STAT3 is essential for Hodgkin lymphoma cell proliferation and is target of tyrphostin AG17 which confers sensitization for apoptosis. Leukemia, 19 (2005), 6, S. 936-944.
Lange F, Bajtner E, Caspar T, Rintisch C, Nandakumar KS, Sack U, Holmdahl R. Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis. Ann Rheum Dis, 64 (2005), 4, S. 599-605.
Lenk K, Adams V, Lurz P, Erbs S, Linke A, Gielen S, Schmidt A, Scheinert D, Biamino G, Emmrich F, Schuler G, Hambrecht R. Therapeutical potential of blood-derived progenitor cells in patients with peripheral arterial occlusive disease and critical limb ischaemia. Eur Heart J, 26 (2005), 18, S. 1903-1909.
Lenz D, Barten MJ, Hiller S, Tarnok A, Sack U. Regenerative and predictive medicine of cardiovascular disease: the 9th Leipziger Workshop and the 2nd International Workshop on slide based cytometry. Cytom Part A, 64 (2005), 2, S. 110-114.
Linke A, Adams V, Schulze PC, Erbs S, Gielen S, Fiehn E, Mobius-Winkler S, Schubert A, Schuler G, Hambrecht R. Antioxidative effects of exercise training in patients with chronic heart failure. Increase in radical scavenger enzyme activity in skeletal muscle. Circulation, 111 (2005), 14, S. 1763-70.
Mittag A, Lenz D, Gerstner AO, Sack U, Steinbrecher M, Koksch M, Raffael A, Bocsi J, Tarnok A. Polychromatic (eight-color) slide-based cytometry for the phenotyping of leukocyte, NK, and NKT subsets. Cytom Part A, 65 (2005), 2, S. 103-115.
Moche M, Hui DSC, Huse K, Chan KS, Choy DKL, Tannapfel A, Scholz GH, Gosse H, Sack U, Hoheisel G. Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion. Pneumologie, 59 (2005), 8, S. 523-528.
Pelz O, Wu M, Nikolova T, Kamprad M, Ackermann M, Egger D, Emmrich F, Wobus AM, Cross M. Duplex polymerase chain reaction quantification of human cells in a murine background. Stem Cells, 23 (2005), 6, S. 828-833.
Pohlers D, Siegling A, Buchner E, Schmidt-Weber CB, Palombo-Kinne E, Emmrich F, Brauer R, Kinne RW. Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis. Arthritis Res Ther, 7 (2005), 3, S. 445-457.
Rastan AJ, Walther T, Kostelka M, Garbade J, Schubert A, Stein A, Dhein S, Mohr FW. Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells-an in vitro-model. Eur J Cardio-Thorac, 27 (2005), 1, S. 104-10.
Sack U, Hirth A, Funke B, Wiedemeyer K, Lange F, Troltzsch M, Tannapfel A, Gebhardt R, Emmrich F, Lehmann J. A novel model of fibroblast-mediated cartilage destruction. Scand J Immunol, 61 (2005), 1, S. 18-28.
Sack U, Hoffmann M, Zhao XJ, Chan KS, Hui DS, Gosse H, Engelmann L, Schauer J, Emmrich F, Hoheisel G. Vascular endothelial growth factor in pleural effusions of different origin. Eur Respir J, 25 (2005), 4, S. 600-604.
Sack U, Sehm B, Kahlenberg F, Murr A, Lehmann J, Tannapfel A, Uberla K, Moessner A, Dietrich A, Emmrich F, Lange F, Jungel A, Braun JM, Anderegg U. Investigation of arthritic joint destruction by a novel fibroblastbased model. Ann NY Acad Sci 1051 (2005), 1, S. 291-298.
Schastak S, Jean B, Handzel R, Kostenich G, Hermann R, Sack U, Orenstein A, Wang YS, Wiedemann P. Improved pharmacokinetics, biodistribution and necrosis in vivo using a new near infra-red photosensitizer: tetrahydroporphyrin tetratosylat. J Photoch Photobio B, 78 (2005), 3, S. 203-213.
Schneider A, Sack U, Rothe K, Bennek J. Peritoneal taurolidine lavage in children with localised peritonitis due to appendicitis. Pediatr Surg Int 21 (2005), 6, S. 445-448.
Stolzing A, Sethe S, Grune T. Chronically active - role of oxidative stress in age and neuropathology. Redox Rep, 10 (2005), 4, S. 207-13.
Wötzel M, Schröder S, Sack U. Differentiation of anti-platelet antibodies using microspheres and flow cytometry. J Lab Clin Med (2005), 29, S. 368-376.
zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ. Induction of chondro-, osteoand adipogenesis in embryonic stem cells by bone morphogenetic protein-2: Effect of co-factors on differentiating lineages. BMC Dev Biol 5 (2005), 1, S. 1-15.

Publikationen 2006

Baumann JG. Intracellular restriction factors in mammalian cells – an ancient defense system finds a modern foe. Curr HIV Res, 4 (2006), 2, S. 141-168.
Birkenmeier G, Nicklisch S, Pockelt C, Mossie A, Steger V, Glaser C, Hauschildt S, Usbeck E, Huse K, Sack U, Bauer M, Schafer A. Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: modes of action and impact on lethality. J Pharmacol Exp Ther, 318 (2006), 2, S. 762-771.
Bocsi J, Lenz D, Mittag A, Varga VS, Molnar B, Tulassay Z, Sack U, Tarnok A. Automated four-color analysis of leukocytes by scanning fluorescence microscopy using quantum dots. Cytom Part A, 69 (2006), 3, S. 131-134.
Bocsi J, Mittag A, Sack U, Gerstner AO, Barten MJ, Tarnok A. Novel aspects of systems biology and clinical cytomics. Cytom Part A, 69 (2006), 3, S. 105-108.
Boltze J, Kowalski I, Forschler A, Schmidt U, Wagner D, Lobsien D, Emmrich J, Egger D, Kamprad M, Blunk J, Emmrich F. The stairway: a novel behavioral test detecting sensomotoric stroke deficits in rats. Artif Organs, 30 (2006), 10, S. 756-763.
Brocke-Heidrich K, Ge B, Cvijic H, Pfeifer G, Loffler D, Henze C, McKeithan TW, Horn F. BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription. Oncogene, 25 (2006), 55, S. 7297-7304.
Colsman A, Sticherling M, Stopel C, Emmrich F. Computer-assisted learning in medicine : how to create a novel software for immunology. Arch Dermatol Res, 298 (2006), 1, S. 1-6.
Cormier JT, zur Nieden NI, Rancourt DE, Kallos MS. Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors. Tissue Eng, 12 (2006), 11, S. 3233-3245.
Dietrich A, Stockmar C, Aust G, Endesfelder S, Guetz A, Sack U, Schoenfelder M, Hauss J. Intraoperative subcutaneous or intrasplenic vaccination with modified autologous tumor cells leads to enhanced survival in a mouse tumor model. J Cancer Res Clin, 132 (2006), 6, S. 379-388.
Ehlers J, Alt M, Trepnau D, Lehmann J. Anwendung neuer Immunglobulin-isotypspezifischer ELISA-Systeme zur Erkennung von Salmonelleninfektionen bei Schweinen. Berl Munch Tierarztl 119 (2006), 11-12, S. 461-466.
Emmrich F. Regenerative Medizin – Made in Germany. Zeitschrift für Regenerative Medizin, 1. Jahrg. (2006), 1.
Funke B, Jungel A, Schastak S, Wiedemeyer K, Emmrich F, Sack U. Transdermal photodynamic therapy-a treatment option for rheumatic destruction of small joints? Laser Surg Med, 38 (2006), 9, S. 866-874.
Giese M, Liebert UG, Schneider T, Bock K, Zahn N, Uhlig A, Schusser GF. Therapeutical immunization of EAV-infected horses by DNA-Vaccination. Reprod Domest Anim 41 (2006), 4, S. 297-298.
Härtig W, Lehmann J, Stieler J, Singer D, Grosche J, Arendt T, Hoffmann R. Simultaneous detection of tau phospho-epitopes with haptenylated antibodies. Neuroreport, 17 (2006), 9, S. 869-875.
Hemdan NY, Emmrich F, Sack U, Wichmann G, Lehmann J, Adham K, Lehmann I. The in vitro immune modulation by cadmium depends on the way of cell activation. Toxicology 222 (2006), 1-2, S. 37-45.
Hiemann R, Hilger N, Sack U, Weigert M. Objective quality evaluation of fluorescence images to optimize automatic image acquisition. Cytom Part A, 69 (2006), 3, S. 182-184.
Kirsten H, Dienst S, Emmrich F, Ahnert P. CalcDalton: a tool for multiplex genotyping primer design for single-base extension reactions using cleavable primers. Biotechniques, 40 (2006), 2, S. 158-160.
Koschny R, Holland H, Koschny T, Vitzthum HE. Comparative genomic hybridization pattern of non-anaplastic and anaplastic oligodendrogliomas – a meta-analysis. Pathol Res Pract, 202 (2006), 1, S. 23-30.
Lange F, Hartl S, Ungethuem U, Kuban RJ, Hammerschmidt S, Faber S, Morawietz L, Wirtz H, Emmrich F, Krenn V, Sack U. Anti-TNF effects on destructive fibroblasts depend on mechanical stress. Scand J Immunol, 64 (2006), 5, S. 544-553.
Lehmann J, Springer S, Werner CE, Lindner T, Bellmann S, Straubinger RK, Selbitz HJ, Alber G. Immunity induced with a Salmonella enterica serovar enteritidis live vaccine is regulated by Th1-cell-dependent cellular and humoral effector mechanisms in susceptible BALB/c mice. Vaccine, 24 (2006), 22, S. 4779-4793.
Mishto M, Bellavista E, Santoro A, Stolzing A, Ligorio C, Nacmias B, Spazzafumo L, Chiapelli M, Licastro F, Sorbi S, Pession A, Ohm T, Grune T, Franceschi C. Immunoproteasome and LMP2 polymorphism in aged and Alzheimer’s disease brains. Neurobiol Aging, 27 (2006), 1, S. 54-66.
Mittag A, Lenz D, Bocsi J, Sack U, Gerstner AO, Tarnok A. Sequential photobleaching of fluorochromes for polychromatic slide-based cytometry. Cytom Part A, 69 (2006), 3, S. 139-141.
Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Kuss O, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R. Endothelial protection, AT1 blockade and cholesterol-dependent oxidative stress: the EPAS trial. Circulation, 114 (2006), 1, S. 1296-1301.
Mückstein U, Tafer H, Hackermüller J, Bernhart SH, Stadler PF, Hofacker IL. Thermodynamics of RNA-RNA binding. Bioinformatics 22 (2006), 10, S. 1177-1182.
Müller H, Johne R, Schusser G, Giese M, Linke S, Pauli G. West Nile Virus - Causative agent of a zoonosis with increasing significance? Deut Tierarztl Woch 113 (2006), 12, S. 435-439.
Pohl S, Fricke S, Hildebrandt G, Uharek L, Braun JM, Emmrich F. Permanent induction of specific immunotolerance to allograft and prevention of graft-versushost-disease. Zeitschrift für Regenerative Medizin (2006), 1, S. 60.
Poppek D, Keck S, Ermack G, Jung T, Stolzing A, Ullrich O, Davies KJ, Grune T. Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress. Biochem J 400 (2006), 3, S. 511-520.
Rulli SJjr, Muriaux D, Nagashima K, Mirro J, Oshima M, Baumann JG, Rein A. Mutant murine leukemia virus Gag proteins lacking proline at the N-terminus of the capsid domain block infectivity in virions containing wild-type Gag. Virology, 347 (2006), 2, S. 364-371.
Sack U, Biereder B, Elouahidi T, Bauer K, Keller T, Trobs RB. Diagnostic value of blood inflammatory markers for detection of acute appendicitis in children. BMC Surg 6 (2006), 15.
Sack U, Scheibe R, Wötzel M, Hammerschmidt S, Kuhn H, Emmrich F, Hoheisel G, Wirtz H, Gessner C. Multiplex analysis of cytokines in exhaled breath condensate. Cytom Part A, 69 (2006), 3, S. 169-172.
Seleverstov O, Zabirnyk O, Zscharnack M, Bulavina L, Nowicki M, Heinrich JM, Yezhelyev M, Emmrich F, O Regan R, Bader A. Quantum dots for human mesenchymal stem cells labeling. A size-dependent autophagy activation. Nano Lett, 6 (2006), 12, S. 2826-2832.
Selig L, Sack U, Gaiser S, Kloppel G, Savkovic V, Mossner J, Keim V, Bodeker H. Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen. BMC Gastroenterol (2006), 6, S. 30ff.
Sethe S, Scutt A, Stolzing A. Aging of mesenchymal stem cells. Aging Res Rev (2006), 5, S. 91-116.
Singer D, Lehmann J, Hanisch K, Härtig W, Hoffmann R. Neighbored phosphorylation sites as PHF-tau specific markers in Alzheimer’s disease. Biochem Bioph Res Co (2006), 346, S. 819-828.
Stolzing A, Scutt A. Age-related impairment of mesenchymal progenitor cell function. Aging Cell (2006), 5, S. 213-224.
Stolzing A, Scutt A. Effect of reduced culture temperature on antioxidant defences of mesenchymal stem cells. Free Radical Bio Med, 41 (2006), 2, S. 326-38.
Stolzing A, Scutt A. Glucose-induced replicative senescence in mesenchymal stem cells. Rejuv Res, 9 (2006), 1, S. 31-35.
Stolzing A, Sethe S, Scutt A. Stressed stem cells: temperature response in aged mesenchymal stem cells. Stem Cells Dev, 15 (2006), 4, S. 478-87.
Stolzing A, Widmer R, Jung T, Grune T. Tocopherol-mediated modulation of age-related changes in microglial cells: turnover of extracellular oxidized protein material. Free Radical Bio Med 40 (2006), 12, S. 2126-2135.
Stolzing A, Widmer R, Jung T, Voss P, Grune T. Degradation of glycated bovine serum albumin in microglial cells. Free Radical Bio Med, 40 (2006), 6, S. 1017-1027.
Walther T, Schubert A, Wustmann T, Falk V, Walther C, Doll N, Rastan A, Gummert J, Mohr FW. Reverse remodeling of cardiac collagen protein expression after surgical therapy for experimental aortic stenosis. J Heart Valve Dis, 15 (2006), 5, S. 651-6.