Publication list

Publication list 2018

  • Andersen JL, Fagerberg R, Flamm C, Kianian R, Merkle D, Stadler PF. Towards mecha­nistic prediction of mass spectra using graph trans­formation. Match 80 (2018), Nr.3, S. 705-731. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_705-731.pdf
  • Andersen JL, Flamm C, Merkle D, Stadler PF. Rule composition in graph transformation models of chemical reactions. Match 80 (2018), Nr.3, S. 661-704. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_661-704.pdf
  • Bahner N, Reich P, Frense D, Menger M, Schieke K, Beckmann D. An aptamer-based biosensor for detection of doxorubicin by electro­chemical impedance spectroscopy. Analytical and Bioanalytical Chemistry 410 (2018), 5, S. 1453-1462. dx.doi.org/10.1007/s00216-017-0786-8
  • Baqué M, Hanke F, Böttger U, Leya T, Moeller R, Vera JP de. Protection of cyanobacterial carotenoids‘ Raman signatures by Martian mineral analogues after high-dose gamma irradiation. Journal of Raman Spectroscopy 49 (2018), 10, S. 1617-1627. dx.doi.org/10.1002/jrs.5449
  • Bayer L, Fertey J, Ulbert S, Grunwald T. Immunization with an adjuvanted low-energy electron irradiation inactivated respiratory syncytial virus vaccine shows immunoprotective activity in mice. Vaccine 36 (2018), 12, S. 1561-1569. dx.doi.org/10.1016/j.vaccine.2018.02.014
  • Bayer L, Gümpel J, Hause G, Müller M, Grunwald T. Non-human papillomaviruses for gene delivery in vitro and in vivo. PLoS one 13 (2018), Art. e0198996, 14 S. dx.doi.org/10.1371/journal.pone.0198996
  • Behm LVJ, Schlenther I, Petrausch M, Jorde F, Godino N, Pfisterer F, Duschl C, Kirschbaum M. A simple approach for the precise measurement of surface temperature distributions on the microscale under dry and liquid conditions based on thin Rhodamine B films. Sensors and Actuators B-Chemical 255 (2018), S. 2023-2031. dx.doi.org/10.1016/j.snb.2017.09.001
  • Bender P, Egger A, Westermann M, Taudte N, Sculeana A, Potempa J, Möller B, Buchholz M, Eick S. Expression of human and Porphyro­monas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis – A pilot study. Archives of Oral Biology, 97 (2019),S. 223-230. dx.doi.org/10.1016/j.archoralbio.2018.10.022
  • Blaess M, Bibak N, Claus RA, Kohl M, Bonaterra GA, Kinscherf R, Laufer S, Deigner HP. NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation. European journal of medicinal chemistry 153 (2018), S. 73-104. dx.doi.org/10.1016/j.ejmech.2017.09.021
  • Blod C, Schlichting N, Schülin S, Suttkus A, Peukert N, Stingu CS, Hirsch C, Elger W, Lacher M, Bühligen U, Mayer S. The oral microbiome - the relevant reservoir for acute pediatric appendicitis? International journal of colorectal disease 33 (2018), Nr.2, S. 209-218. dx.doi.org/10.1007/s00384-017-2948-8
  • Boltze J, Ferrara F, Hainsworth AH, Bridges LR, Zille M, Lobsien D, Barthel H, McLeod DD, Gräßer F, Pietsch S, Schatzl AK, Dreyer AY, Nitzsche B. Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage. Journal of cerebral blood flow and metabolism Cereb Blood Flow Metab. 2018 (vorab online). dx.doi.org/10.1177/0271678X18802119
  • Canzler S, Stadler PF, Schor J. The fungal snoRNAome. RNA 24 (2018), 3, S. 342-360. dx.doi.org/10.1261/rna.062778.117
  • Donath A, Stadler PF. Split-inducing indels in phylo­genomic analysis. Algorithms for molecular biology. Online journal 13 (2018), Art. 12, 12 S. / dx.doi.org/10.1186/s13015-018-0130-7
  • Dondapati SK, Wüstenhagen DA, Strauch E, Kubick S. Cell-free production of pore forming toxins: Functional analysis of thermostable direct hemo­lysin from Vibrio parahaemolyticus. Engineering in Life Sciences 18 (2018), 2, S. 140-148. dx.doi.org/10.1002/elsc.201600259
  • Dunkelmann T, Teichmann K, Ziehm T, Schemmert S, Frenzel D, Tusche M, Dammers C, Jürgens D, Langen KJ, Demuth HU, Shah NJ, Kutzsche J, Willuweit A, Willbold D. Aβ oligomer eliminating compounds interfere successfully with pEAβ(3–42) induced motor neuro­degenerative phenotype in transgenic mice. Neuropeptides 67 (2018), S. 27-35. dx.doi.org/10.1016/j.npep.2017.11.011
  • Engel MC, Smith DM, Jobst MA, Sajfutdinow M, Liedl T, Romano F, Rovigatti L, Louis AA, Doye JPK. Force-induced unravelling of DNA origami. ACS nano 12 (2018), 7, S. 6734-6747. dx.doi.org/10.1021/acsnano.8b01844
  • Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V. Roquin targets mRNAs in a 3‘-UTR-specific manner by different modes of regulation. Nature Communi­cations 9 (2018), Art. 3810. dx.doi.org/10.1038/s41467-018-06184-3
  • Fagerberg R, Flamm C, Kianian R, Merkle D, Stadler PF. Finding the K best synthesis plans. Journal of cheminformatics. Online journal 10 (2018), Art. 19, 21 S. dx.doi.org/10.1186/s13321-018-0273-z
  • Fingas F, Rückner A, Heenemann K, Volke D, Sieg M, Bielefeldt P, Grunwald T, Vahlenkamp TW, Hassert R, Hoffmann R. Highly sensitive ELISA for the serological detection of murine rotavirus EDIM based on its major immunogen VP6. Journal of Virological Methods 262 (2018), S. 72-78. dx.doi.org/10.1016/j.jviromet.2018.07.016
  • Fornefett J, Krause J, Klose K, Fingas F, Hassert R, Benga L, Grunwald T, Müller U, Schrödl W, Baums CG. Comparative analysis of humoral immune responses and pathologies of BALB/c and C57BL/6 wildtype mice experimentally infected with a highly virulent Rodenti­bacter pneumotropicus (Pasteurella pneumotropica) strain. BMC microbiology 18 (2018), Article 45, 11 S. dx.doi.org/10.1186/s12866-018-1186-8
  • Fornefett J, Krause J, Klose K, Fingas F, Hassert R, Eisenberg T, Schrödl W, Grunwald T, Müller U, Baums CG. Comparative analysis of clinics, pathologies and immune responses in BALB/c and C57BL/6 mice infected with Streptobacillus moniliformis. Microbes and infection 20 (2018), 2, S. 101-110. dx.doi.org/10.1016/j.micinf.2017.10.001
  • Fueldner C, Kohlschmidt J, Riemschneider S, Schulze F, Zoldan K, Esser C, Hauschildt S, Lehmann J. Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner. Toxicology 409 (2018), S. 80-90. dx.doi.org/10.1016/j.tox.2018.07.011
  • Geiß M, Anders J, Stadler PF, Wieseke N, Hellmuth M. Reconstructing gene trees from Fitch’s xenology relation. Journal of mathe­matical biology 77 (2018), Nr.5, S. 1459-1491. dx.doi.org/10.1007/s00285-018-1260-8
  • Golde T, Huster C, Glaser M, Händler T, Herrmann H, Käs JA, Schnauß J. Glassy dynamics in composite biopolymer networks. Soft matter 14 (2018), Nr.39, S. 7970-7978. dx.doi.org/10.1039/c8sm01061g
  • Greco R, Ciceri F, Noviello M, Bondanza A, Vago L, Oliveira G, Peccatori J, Cieri N, Ruggeri A, Koehl U, Fleischhauer K, Rocha V, Dazzi F, van der Werf SM, Eikema DJ, Terwel SR, Kuball J, Toubert A, Chabannon C, Bonini C; EBMT Cellular Therapy and Immunobiology Working Party (CTIWP). Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP. Bone Marrow Transplant. 53 (2018), S. 1201-1205. dx.doi.org/10.1038/s41409-018-0167-8.
  • Gröger V, Cynis H. Human endogenous retroviruses and their putative role in the development of autoimmune disorders such as Multiple Sclerosis. Frontiers in Micro­biology 9 (2018), 265. dx.doi.org/10.3389/fmicb.2018.00265
  • Grünberg M, Quandt D, Cynis H, Demuth HU, Kindermann A, Magdolen V, Forssmann WG, Seliger B, Mägert HJ. Kallikrein-related peptidases are activators of the CC chemokine CCL14. European Journal of Immunology 48 (2018), 9, S. 1592-1594. dx.doi.org/10.1002/eji.201747452
  • Hartlage-Rübsamen M, Bluhm A, Piechotta A, Linnert M, Rahfeld JU, Demuth HU, Lues I, Kuhn PH, Lichtenthaler SF, Roßner S, Höfling C. Immunohistochemical evidence from APP-transgenic mice for glutaminyl cyclase as drug target to diminish pE-abeta formation. Molecules 23 (2018), 4, Art. 924, 17 S. dx.doi.org/10.3390/molecules23040924
  • Hilger N, Müller C, Stahl L, Müller AM, Zönnchen B, Dluczek S, Halbich C, Wickenhauser C, Gerloff D, Wurm AA, Behre G, Kretschmer A, Fricke, S. Incubation of Immune Cell Grafts With MAX.16H5 IgG1 Anti-Human CD4 Antibody Prolonged Survival After Hematopoietic Stem Cell Transplantation in a Mouse Model for Fms Like Tyrosine Kinase 3 Positive Acute Myeloid Leukemia. Frontiers in Immunology 9 (2018), 2408. dx.doi.org/10.3389/fimmu.2018.02408
  • Hoffmann A, Fallmann J, Vilardo E, Mörl M, Stadler PF, Amman F. Accurate mapping of tRNA reads. Bioinformatics 34 (2018), Nr.7, S. 1116-1124. dx.doi.org/10.1093/bioinformatics/btx756
  • Hoffmann M, Schwertassek U, Seydel A, Weber K, Falk W, Hauschildt S, Lehmann J. A refined and translationally relevant model of chronic DSS colitis in BALB/c mice. Laboratory Animals 53 (2018), 3, S. 240-252. dx.doi.org/10.1177/0023677217742681
  • Kaiser L, Weisser J, Kohl M, Deigner HP. Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection. Scientific Reports 8 (2018), Art: 5628. dx.doi.org/10.1038/s41598-018-23963-6
  • Kern K, Havenith H, Delaroque N, Rautenberger P, Lehmann J, Fischer M, Spiegel H, Schillberg S, Ehrentreich-Foerster E, Aurich S, Treudler R, Szardenings M. The immunome of soybean allergy: Comprehensive identification and characterization of epitopes. Clinical & experimental allergy 49 (2019), 2, S. 239-251. dx.doi.org/10.1111/cea.13285
  • Kersting, S, Rausch, V, Bier, FF, von Nickisch-Rosenegk, M. A recombinase polymerase amplification assay for the diagnosis of atypical pneumonia. Analytical Biochemistry 550 (2018),
    S. 54-60. dx.doi.org/10.1016/j.ab.2018.04.014
  • Knigge X, Wenger C, Bier FF, Hölzel R. Dielectrophoretic immobilisation of nano­particles as isolated singles in regular arrays. Journal of Physics D-Applied Physics 51 (2018), 6, 065308, 10 S. dx.doi.org/10.1088/1361-6463/aaa528
  • Koertge A, Wasserkort R, Wild T, Mitzner S. Extracorporeal Hemoperfusion as a Potential Therapeutic Option for Critical Accumulation of Rivaroxaban. Blood Purification 45 (2018), 126–128. dx.doi.org/10.1159/000484923
  • Köhl U, Arsenieva S, Holzinger A, Abken H. CAR T Cells in Trials: Recent Achievements and Challenges that Remain in the Production of Modified T Cells for Clinical Applications. Human gene therapy 29 (2018), 5, S. 559-568. dx.doi.org/10.1089/hum.2017.254
  • Königs C, Schultze-Strasser S, Quaiser A, Bochennek K, Schwabe D, Klingebiel TE, Koehl U, Cappel C, Rolle U, Bader P, Bremm M, Huenecke S, Bakhtiar S. An exponential regression model reveals the continuous development of B cell subpopulations used as reference values in children. Frontiers in Pediatrics 6 (2018), 121. dx.doi.org/10.3389/fped.2018.00121
  • Körtge A, Wild T, Heskamp B, Folk M, Mitzner S, Wasserkort R. Thrombogenicity and long-term cytokine removal capability of a novel asymmetric triacetate membrane hemofilter. Journal of artificial organs 21 (2018), 4, S. 435-442. dx.doi.org/10.1007/s10047-018-1062-1
  • Kuhlmann JD, Chebouti I, Kimmig R, Buderath P, Reuter M, Puppel SH, Wimberger P, Kasimir-Bauer S. Extracellular vesicle-associated miRNAs in ovarian cancer - design of an integrated NGS-based workflow for the identification of blood-based biomarkers for platinum-resistance. Clinical chemistry and laboratory medicine 13.11.2018. dx.doi.org/10.1515/cclm-2018-1048
  • Kuhn S, Splith K, Ballschuh C, Feldbrügge L, Krenzien F, Atanasov G, Benzing C, Hau HM, Engelmann C, Berg T, Schulte Am Esch J, Pratschke J, Robson SC, Schmelzle M. Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner. Purinergic Signalling 14 (2018), 4, S. 423-432. dx.doi.org/10.1007/s11302-018-9624-5
  • Lang A, Volkamer A, Behm L, Röblitz S, Ehrig R, Schneider M, Geris L, Wichard J, Buttgereit F. In silico methods - computational alternatives to animal testing. ALTEX 35 (2018), 1, S. 124-126. dx.doi.org/10.14573/altex.1712031
  • Laux EM, Ermilova E, Pannwitz D, Gibbons J, Hölzel R, Bier FF. Dielectric Spectroscopy of Biomolecules up to 110 GHz. Frequenz 72 (2018), 3-4, S. 135-140. dx.doi.org/10.1515/freq-2018-0010
  • Laux, EM, Bier, FF, Hölzel, R. Electrode-based AC electro­kinetics of proteins: A mini-review. Bioelectro­chemistry 120 (2018), S. 76-82. dx.doi.org/10.1016/j.bioelechem.2017.11.010
  • Liu Y, Schulze-Makuch D, Vera JP de, Cockell C, Leya T, Baqué M, Walther-Antonio M. The development of an effective bacterial single-cell lysis method suitable for whole genome amplification in microfluidic platforms. Micromachines 9 (2018), 8, art. no. 367, 17 S. dx.doi.org/10.3390/mi9080367
  • Lorenz JS, Schnauß J, Glaser M, Sajfutdinow M, Schuldt C, Käs JA, Smith DM. Synthetic transient crosslinks program the mechanics of soft, biopolymer-based materials. Advanced Materials 30 (2018), Art: 1706092, 8 S. dx.doi.org/10.1021/acs.jmedchem.8b00330
  • Madaboosi N, Uhlig K, Schmidt S, Vikulina AS, Möhwald H, Duschl C, Volodkin D. A »cell-friendly« window for the interaction of cells with hyaluronic acid/poly-l-lysine multilayers. Macromolecular Bioscience 18 (2018), 2, art. no. 1700319. dx.doi.org/10.1002/mabi.201700319
  • Moreira-Soto A, Cabral R, Pedroso C, Eschbach-Bludau M, Rockstroh A, Vargas LA, Postigo-Hidalgo I, Luz E, Sampaio GS, Drosten C, Netto EM, Jaenisch T, Ulbert S, Sarno M, Brites C, Drexler JF. Exhaustive TORCH Pathogen Diagnostics Corroborate Zika Virus Etiology of Congenital Malformations in North­eastern Brazil. mSphere. 3 (2018), 4, e00278-18. dx.doi.org/10.1128/mSphere.00278-18
  • Möser C, Lorenz JS, Sajfutdinow M, Smith DM. Pinpointed Stimulation of EphA2 Receptors via DNA-Templated Oligovalence. International Journal of Molecular Sciences (2018), Nr.19, 19 S. dx.doi.org/10.3390/ijms19113482
  • Müller B, Boltze J, Czepezauer I, Hesse V, LEGASCREEN Consortium, Wilcke A, Kirsten H. Dyslexia risk variant rs600753 is linked with dyslexia-specific differential allelic expression of DYX1C1. Genetics and molecular biology 41 (2018), Nr.1, S. 41-49. dx.doi.org/10.1590/1678-4685-gmb-2017-0165
  • Nøjgaard N, Geiß M, Merkle D, Stadler PF, Wieseke N, Hellmuth M. Time-consistent reconciliation maps and forbidden time travel. Algorithms for molecular biology. Online journal 13 (2018), Art. 2, 17 S. dx.doi.org/10.1186/s13015-018-0121-8
  • Oberbach A, Schlichting N, Heinrich M, Kullnick Y, Retschlag U, Lehmann S, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism in obese rats. Gastrointestinal endoscopy 87 (2018), Nr.1, S. 288-299. dx.doi.org/10.1016/j.gie.2017.04.038
  • Penna-Martinez M, Filmann N, Bogdanou D, Shoghi F, Huenecke S, Schubert R, Herrmann E, Koehl U, Husebye ES, Badenhoop K. High-dose vitamin D in Addison‘s disease regulates T-cells and monocytes: A pilot trial. Nutrition. 49 (2018), S. 66-73. dx.doi.org/10.1016/j.nut.2017.10.021.
  • Peters F, Westphal C, Kramer A, Westerman R. Is the rise in the prevalence of renal replacement therapy at older ages the price for living longer? Frontiers in Public Health 6 (2018), 138, 7 S. dx.doi.org/10.3389/fpubh.2018.00138
  • Pieroh P, Wagner DC, Alessandri B, Dabbagh Nazari M, Ehrlich A, Ghadban C, Hobusch C, Birkenmeier G, Dehghani F. Comparative examination of temporal glyoxalase 1 variations following perforant pathway transection, excitotoxicity, and controlled cortical impact injury. Neurotoxicity research 33 (2018), Nr.2, S. 412-421. dx.doi.org/10.1007/s12640-017-9808-8
  • Prohaska SJ, Berkemer SJ, Gärtner F, Gatter T, Retzlaff N, Students of the Graphs and Biological Networks Lab 2017, Höner Zu Siederdissen C, Stadler PF. Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem. Journal of mathematical biology 77 (2018), Nr.2, S. 313-341. dx.doi.org/10.1007/s00285-017-1197-3
  • Quaiser A, Köhl U. Was ist gesichert bei den Zelltherapien?: Möglichkeiten und Grenzen in der Immunonkologie. [What is established in cell therapies?: Possibilities and limits in immuno-oncology]. Internist (Berl). 59 (2018), 12, S. 1230-1238. dx.doi.org/10.1007/s00108-018-0516-0
  • Ramsbeck D, Hamann A, Richter G, Schlenzig D, Geissler S, Nykiel V, Cynis H, Schilling S, Buchholz M. Structure-guided design, synthesis and characteriza­tion of next-generation meprin β inhibitors. Journal of medicinal chemistry 61 (2018), 10, S. 4578-4592. dx.doi.org/10.1021/acs.jmedchem.8b00330
  • Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V. Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. Nature Communica­tions 9 (2018), Art. 299, 15 S. dx.doi.org/10.1038/s41467-017-02582-1
  • Retzlaff N, Stadler PF. Phylo­genetics beyond biology. Theory in Biosciences (2018), Online First, 11 S. dx.doi.org/10.1007/s12064-018-0264-7
  • Riemschneider S, Kohlschmidt J, Fueldner C, Esser C, Hauschildt S, Lehmann J. Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macro­phages. Toxicology letters 296 (2018), S. 106-113. dx.doi.org/10.1016/j.toxlet.2018.07.050
  • Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut 67 (2018), 10, S. 1855-1863. dx.doi.org/10.1136/gutjnl-2017-314454
  • Rüppel N, Tröger V, Sandetskaya N, Kuhlmeier D, Schmieder S, Sonntag F. Detection and identification of staphylococcus aureus using magnetic particle enhanced surface plasmon spectroscopy. Engineering in life sciences 18 (2018), 4, S. 263-268. dx.doi.org/10.1002/elsc.201700098
  • Sajfutdinow M, Jacobs WM, Reinhardt A, Schneider C, Smith DM. Direct observation and rational design of nucleation behavior in addressable self-assembly. Proceedings of the National Academy of Sciences of the United States of America : PNAS 115 (2018), 26, S. E5877-E5886. dx.doi.org/10.1073/pnas.1806010115
  • Salzmann-Manrique E, Bremm M, Huenecke S, Stech M, Orth A, Eyrich M, Schulz A, Esser R, Klingebiel T, Bader P, Herrmann E, Koehl U. Joint Modeling of Immune Reconstitution Post Haploidentical Stem Cell Transplantation in Pediatric Patients With Acute Leukemia Comparing CD34+-Selected to CD3/CD19-Depleted Grafts in a Retrospective Multicenter Study. Frontiers in Immunology 9 (2018), 1841, 12 S. dx.doi.org/10.3389/fimmu.2018.01841
  • Sauer M, Haubner C, Richter G, Ehler J, Mencke T, Mitzner S, Margraf S, Altrichter J, Doß S, Nöldge-Schomburg G v. Impaired cell viability and functionality of hepatocytes after incubation with septic plasma-results of a second prospective biosensor study. Frontiers in Immunology. 9 (2018), 1448. dx.doi.org/10.3389/fimmu.2018.01448
  • Sauer M, Richter G, Altrichter J, Wild T, Doß F, Mencke T, Ehler J, Doß S, Koch S, Schubert A, Nöldge-Schomburg G, Mitzner SR. Effects of Bioreactor-Oxygenation During Extracorporeal Granulocytes Treatment in Septic Patients. Therapeutic apheresis and dialysis 22 (2018), 4, S. 389-398. dx.doi.org/10.1111/1744-9987.12657
  • Schäffler H, Breitrück A. Clostridium difficile - from colonization to infection. Frontiers in Microbiology 9 (2018), 646. dx.doi.org/10.3389/fmicb.2018.00646
  • Schilling S, Rahfeld JU, Lues I, Lemere CA. Passive Aβ immunotherapy: Current achievements and future perspectives. Molecules 23 (2018), 5, Art. 1068, 14 S. dx.doi.org/10.3390/molecules23051068
  • Schlenzig D, Cynis H, Hartlage-Ruebsamen M, Zeitschel U, Menge K, Fothe A, Ramsbeck D, Spahn C, Wermann M, Rossner S, Buchholz M, Schilling S, Demuth HU. Dipeptidyl-Peptidase activity of Meprin _ Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ formation. Journal of Alzheimer’s Disease 66 (2018) 359-375. dx.doi.org/10.3233/JAD-171183
  • Schneider T, Hahn-Löbmann S, Stephan A, Schulz S, Giritch A, Naumann M, Kleinschmidt M, Tusé D, Gleba Y. Plant-made Salmonella bacteriocins salmocins for control of Salmonella pathovars. Scientific Reports 8 (2018), Art: 4078. dx.doi.org/10.1038/s41598-018-22465-9
  • Schnotalle P, Koch K, Au-Yeung RKH, Reinke S, Winter K, Loeffler M, Braumann UD, Klapper W. T-Cell clustering in neoplastic follicles of follicular lymphoma. Cancer Micro­environment 11 (2018), 2-3, 135-140. dx.doi.org/10.1007/s12307-018-0217-1
  • Schultze-Florey RE, Tischer S, Kuhlmann L, Hundsdoerfer P, Koch A, Anagnostopoulos I, Ravens S, Goudeva L, Schultze-Florey C, Koenecke C, Blasczyk R, Koehl U, Heuft HG, Prinz I, Eiz-Vesper B, Maecker-Kolhoff B. Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease. Frontiers in Immunology. 9 (2018), 1475. dx.doi.org/10.3389/fimmu.2018.01475
  • Schulze A, Wermann M, Demuth HU, Yoshimoto T, Ramsbeck D, Schlenzig D, Schilling S. Continuous assays for meprin alpha and beta using prolyl tripeptidyl aminopeptidase (PtP) from Porphyromonas gingivalis. Analytical biochemistry 559 (2018), S. 11-16. dx.doi.org/10.1016/j.ab.2018.08.005
  • Stadler BMR,Stadler PF. Reachability, connectivity, and proximity in chemical spaces. Match 80 (2018), Nr.3, S. 639-659. http://match.pmf.kg.ac.rs/electronic_versions/Match80/n3/match80n3_639-659.pdf
  • Sustr D, Hlaváček A, Duschl C, Volodkin D. Multi-Fractional Analysis of Molecular Diffusion in Polymer Multi­layers by FRAP: A New Simulation-Based Approach. Journal of Physical Chemistry B 122 (2018), 3, S. 1323-1333. dx.doi.org/10.1021/acs.jpcb.7b11051
  • Tan K, Jäger C, Schlenzig D, Schilling S, Buchholz M, Ramsbeck D. Tertiary-amine-based inhibitors of the astacin protease meprin α. ChemMedChem 13 (2018), 16, S. 1619-1624. dx.doi.org/10.1002/cmdc.201800300
  • Terekhov R, Selivanova I. Fractal aggregation of dihydro­quercetin after lyophilization. Journal of Pharmaceutical Innovation (2018), S. 1-8. dx.doi.org/10.1007/s12247-018-9322-4
  • Thalheim T, Quaas M, Herberg M, Braumann UD, Kerner C, Loeffler M, Aust G, Galle J. Linking stem cell function and growth pattern of intestinal organoids. Developmental Biology 433 (2018), 2, S. 254-261. dx.doi.org/10.1016/j.ydbio.2017.10.013
  • Trento C, Bernardo ME, Nagler A, Kuçi S, Bornhäuser M, Köhl U, Strunk D, Galleu A, Sanchez-Guijo F, Gaipa G, Introna M, Bukauskas A, Le Blanc K, Apperley J, Roelofs H, Van Campenhout A, Beguin Y, Kuball J, Lazzari L, Avanzini MA, Fibbe W, Chabannon C, Bonini C, Dazzi F. Manufactur­ing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers
    Affiliated with the European Society for Blood and Marrow Transplantation.
    Biology of blood marrow transplantion 24 (2018), 11, S. 2365-2370. dx.doi.org/10.1016/j.bbmt.2018.07.015
  • Uhlig K, Wegener T, Hertle Y, Bookhold J, Jaeger M, Hellweg T, Fery A, Duschl C. Thermo­responsive Microgel Coatings as Versatile Functional Compounds for Novel Cell Manipulation Tools. Polymers 10 (2018), 6, Art: 656. dx.doi.org/10.3390/polym10060656
  • van Belkum A, Bachmann TT, Lüdke G, Lisby JG, Kahlmeter G, Mohess A, Becker K, Hays JP, Woodford N, Mitsakakis K, Moran-Gilad J, Vila J, Peter H, Rex JH, Dunne WM Jr;
    JPIAMR AMR-RDT Working Group on Antimicrobial Resistance and Rapid Diagnostic Testing. Developmental roadmap for antimicrobial susceptibility testing systems. Nature Reviews Microbiology (2018), 12 S., article in press. dx.doi.org/10.1038/s41579-018-0098-9
  • Vikulina AS, Feoktistova NA, Balabushevich NG, Skirtach AG, Volodkin D. The mechanism of catalase loading into porous vaterite CaCO3 crystals by co-synthesis. Physical Chemistry Chemical Physics 20 (2018), 13, S. 8822-8831. dx.doi.org/10.1039/c7cp07836f
  • Vladimirov GK, Vikulina AS, Volodkin D, Vladimirov YA. Structure of the complex of cytochrome c with cardiolipin in non-polar environment. Chemistry and Physics of Lipids 214 (2018), S. 35-45. dx.doi.org/10.1016/j.chemphyslip.2018.05.007
  • Walcher L, Müller C, Hilger N, Kretschmer A, Stahl L, Wigge S, Rengelshausen J, Müller AM, Fricke S. Effect of combined sublethal X-ray irradiation and cyclosporine A treatment in NOD scid gamma (NSG) mice. Experimental animals (2018), Art. 18-0056, 26 S. dx.doi.org/10.1538/expanim.18-0056
  • Walter Costa MB, Höner Zu Siederdissen C, Tulpan D, Stadler PF, Nowick K. Temporal ordering of substitutions in RNA evolution: Uncovering the structural evolution of the Human Accelerated Region 1. Journal of theoretical biology 438 (2018), S. 143-150. dx.doi.org/10.1016/j.jtbi.2017.11.015
  • Wiegreffe D, Müller L, Steuck J, Zeckzer D, Stadler PF. The Sierra Platinum Service for generat­ing peak-calls for replicated ChIP-seq experiments. BMC research notes. Online journal 11 (2018), Art. 512, 5 S. dx.doi.org/10.1186/s13104-018-3633-x
  • Wuchty S, Müller SA, Caufield JH, Häuser R, Aloy P, Kalkhof S, Uetz P. Proteome data improves protein function prediction in the interactome of Helicobacter pylori. Molecular & cellular proteomics 17 (2018), Nr.5, S. 961-973. dx.doi.org/10.1074/mcp.RA117.000474
  • Zemella A, Thoring L, Hoffmeister C, Šamalíková M, Ehren P, Wüstenhagen DA, Kubick S. Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin. Scientific Reports 8 (2018), 8514. dx.doi.org/10.1038/s41598-018-26936-x

Publications 2017

  • Agocs E, Kozma P, Nador J, Hamori A, Janosov M, Kalas B, Kurunczi S, Fodor B, Ehrentreich-Förster E, Fried M, Horvath R, Petrik P. Grating coupled optical waveguide interferometry combined with in situ spectroscopic ellipsometry to monitor surface processes in aqueous solutions. Applied surface science 421 (2017), Pt. B, S. 289-294. dx.doi.org/10.1016/j.apsusc.2016.07.166
  • Ahn J-S, Kim H-J, Kim YK, Lee S-S, Ahn SY, Jung SH, Yang DH, Lee JJ, Park HJ, Choi SH, Jung CW, Jang JH, Kim HJ, Moon JH, Sohn SK, Won JH, Kim SH, Szardenings M, Minden M, Hwan K, Dennis D. 5-Hydro-xymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia. OncoTarget. 8 (2017), 5, S. 8305-8314. dx.doi.org/10.18632/oncotarget.14171
  • Al Arab M, Bernt M, Höner Zu Siederdissen C, Tout K, Stadler PF. Partially local three-way alignments and the sequence signatures of mitochondrial genome rearrangements. Algorithms for molecular biology. 12 (2017), 22, 11 S. dx.doi.org/10.1186/s13015-017-0113-0
  • Al-Arab M, Höner zu Siederdissen C, Tout KR, Sahyoun AH, Stadler PF, Bernt M. Accurate annotation of protein-coding genes in mitochondrial genomes. Molecular phylogenetics and evolution 106 (2017), S. 209-216. dx.doi.org/10.1016/j.ympev.2016.09.024
  • Ambrosius B, Faissner S, Guse K, von Lehe M, Grunwald T, Gold R, Grewe B, Chan A. Teriflunomide and mono-methylfumarate target HIV-induced neuro-inflammation and neurotoxicity. Journal of neuroinflammation 14 (2017), Art. 51, 10 S. dx.doi.org/10.1186/s12974-017-0829-2
  • Andersen JL, Flamm C, Merkle D, Stadler PF. An intermediate level of abstraction for computational systems chemistry. Philosphical Transactions of the Royal Society A. 375 (2017), 2109, 20160354. dx.doi.org/10.1098/rsta.2016.0354
  • Antonyan A, Schlenzig D, Schilling S, Naumann M, Sharoyan S, Mardanyan S, Demuth HU. Concerted action of dipeptidyl peptidase IV and glutaminyl cyclase results in formation of pyro-glutamate-modified amyloid peptides in vitro. Neurochemistry International. 113 (2018), S. 112-119. dx.doi.org/10.1016/j.neuint.2017.12.001
  • Backofen R, Engelhardt J, Erxleben A, Fallmann J, Grüning B, Ohler U, Rajewsky N, Stadler PF. RNA-bioinformatics: Tools, services and databases for the analysis of RNA-based regulation. Journal of biotechnology. 261 (2017), S. 76-84. dx.doi.org/10.1016/j.jbiotec.2017.05.019
  • Bahner N, Reich P, Frense D, Menger M, Schieke K, Beckmann D. An aptamer-based biosensor for detection of doxorubicin by electro-chemical impedance spectroscopy. Analytical and Bioanalytical Chemistry. 410 (2018), 5, S. 1453-1462. dx.doi.org/10.1007/s00216-017-0786-8
  • Behm LVJ, Schlenther I, Petrausch M, Jorde F, Godino N, Pfisterer F, Duschl C, Kirschbaum M. A simple approach for the precise measurement of surface temperature distributions on the microscale under dry and liquid conditions based on thin Rhodamine B films. Sensors and Actuators B-Chemical. 255 (2018), 2, S. 2023–2031. dx.doi.org/10.1016/j.snb.2017.09.001 
  • Berkemer SJ, Hoffmann A, Murray CRA, Stadler PF. SMORE: Synteny Modulator of Repetitive Elements. Life (Basel). 7 (2017), 4, 42, 16 S. dx.doi.org/10.3390/life7040042
  • Binder S, Hösler N, Riedel D, Zipfel I, Buschmann T, Kämpf C, Reiche K, Burger R, Gramatzki M, Hackermüller J, Stadler PF, Horn F. STAT3-induced long noncoding RNAs in multiple myeloma cells display different properties in cancer. Scientific Reports. 7 (2017), 11, Art. 7976, 13 S. dx.doi.org/10.1038/s41598-017-08348-5
  • Buschmann, T. DNABarcodes: An R package for the systematic construction of DNA sample tags. Bioinformatics 33 (2017), 6, S. 920-922. dx.doi.org/10.1093/bioinformatics/btw759
  • Connor D, Danckert L, Hoppe S, Bier FF, von Nickisch-Rosenegk M. Epitope determination of immunogenic proteins of Neisseria gonorrhoeae. PLoS One. 12 (2017), 7, Art. E0180962. dx.doi.org/10.1371/journal.pone.0180962 
  • Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O‘Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European journal of immunology. 47 (2017), 10, S. 1584-1797. dx.doi.org/10.1002/eji.201646632 
  • Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J. Recent progress in translational research on neurovascular and neurodegenerative disorders. Restorative neurology and neuroscience 35 (2017),1, S. 87-103. dx.doi.org/10.3233/RNN-160690
  • Diehl R, Ferrara F, Müller C, Dreyer AY, McLeod DD, Fricke S, Boltze J. Immunosuppression for in vivo research: State-of-the-art protocols and experimental approaches. Cellular and molecular immunology 14 (2017), 2, S. 146-179. dx.doi.org/10.1038/cmi.2016.39
  • Dondapati SK, Wüstenhagen DA, Strauch E, Kubick S. Cell-free production of pore forming toxins: Functional analysis of thermostable direct hemolysin from Vibrio parahaemolyticus. Engineering in Life Sciences. (2017), 9 S. dx.doi.org/10.1002/elsc.201600259
  • Doß S, Potschka H, Doß F, Mitzner S, Sauer M. Hepatotoxicity of antimycotics used for invasive fungal infections: In vitro results. BioMed research international 2017 (2017), Art. 9658018, 10 S. dx.doi.org/10.1155/2017/9658018
  • Dunkelmann T, Teichmann K, Ziehm T, Schemmert S, Frenzel D, Tusche M, Dammers C, Jürgens D, Langen KJ, Demuth HU, Shah NJ, Kutzsche J, Willuweit A, Willbold D. Aβ oligomer eliminating compounds interfere successfully with pEAβ (3–42) induced motor neurodegenerative phenotype in transgenic mice. Neuropeptides, Nov 2017. dx.doi.org/10.1016/j.npep.2017.11.011
  • Ewe A, Panchal O, Pinnapireddy SR, Bakowsky U, Przybylski S, Temme A, Aigner A. Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo. Nanomedicine. Nanotechnology, biology and medicine 13 (2017), 1, S. 209-218. dx.doi.org/10.1016/j.nano.2016.08.005
  • Fandrich A, Buller J, Memczak H, Stöcklein W, Hinrichs K, Wischerhoff E, Schulz B, Laschewsky A, Lisdat F. Responsive polymer-electrode interface-study of its thermo- and pH-sensitivity and the influence of peptide coupling. Electrochimica Acta 229 (2017), S. 325-333. dx.doi.org/10.1016/j.electacta.2017.01.080
  • Findeiß S, Etzel M, Will S, Mörl M, Stadler PF. Design of Artificial Riboswitches as Biosensors. Sensors (Basel). 17 (2017), 9, 1990, 28 S. dx.doi.org/10.3390/s17091990
  • Fischbach J, Loh Q, Bier FF, Lim TS, Frohme M, Glökler J. Alizarin Red S for online pyrophosphate detection identified by a rapid screening method. Scientific Reports. 7 (2017), Art. 45085, 9 S. dx.doi.org/10.1038/srep45085
  • Fornefett J, Krause J, Klose K, Fingas F, Hassert R, Eisenberg T, Schrödl W, Grunwald T, Müller U, Baums CG. Comparative analysis of clinics, pathologies and immune responses in BALB/c and C57BL/6 mice infected with Streptobacillus moniliformis. Microbes and infection. 20 (2018), 2, S. 101-110. dx.doi.org/10.1016/j.micinf.2017.10.001
  • Frimmel S, Mitzner SR, Koball S. Immunoadsorption as a Long-Term Therapy in Recurrent Focal Segmental Glomerulosclerosis After Renal Transplantation. Therapeutic apheresis and dialysis. 21 (2017), 1, S. 108-109. dx.doi.org/10.1111/1744-9987.12487
  • Gessner C, Ruschpler P, Fricke S, Gillissen A, Hoheisel G, Lehmann J, Sack U. Analyses of exhaled breath condensate cytokines for identification of lung cancer. Journal of laboratory medicine 41 (2017), 4, S. 187-194. dx.doi.org/10.1515/labmed-2017-0054 
  • Grochowska KM, Yuanxiang P, Bär J, Raman R, Brugal G, Sahu G, Schweizer M, Bikbaev A, Schilling S, Demuth HU, Kreutz MR. Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO reports 18 (2017), 4, S. 511-657. dx.doi.org/10.15252/embr.201643519
  • Hahn MB, Meyer S, Schröter MA, Seitz H, Kunte HJ, Solomun T, Sturm H. Direct electron irradiation of DNA in fully aqueous environment. Damage determination in combination with Monte Carlo simulations. Physical chemistry chemical physics. 19 (2017), S. 1798-1805. dx.doi.org/10.1039/C6CP07707B
  • Hainsworth AH, Allan SM, Boltze J, Cunningham C, Farris C, Head E, Ihara M, Isaacs JD, Kalaria RN, Lesnik Oberstein SA, Moss MB, Nitzsche B, Rosenberg GA, Rutten JW, Salkovic-Petrisic M, Troen AM. Translational models for vascular cognitive impairment: A review including larger species. BMC medicine 15 (2017), Nr. 1, Art. 16, 12 S. dx.doi.org/10.1186/s12916-017-0793-9
  • Hamidouche Z, Rother K, Przybilla J, Krinner A, Clay D, Hopp L, Fabian C, Stolzing A, Binder H, Charbord P, Galle J. Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity. Stem cells 35 (2017), 3, S. 694-704. dx.doi.org/10.1002/stem.2514
  • Havenith H, Kern K, Rautenberger P, Spiegel H, Szardenings M, Ueberham E, Lehmann J, Buntru M, Vogel S, Treudler R, Fischer R, Schillberg S. Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants. Biotechnology journal 12 (2017), 2, Art. 1600441, 10 S. dx.doi.org/10.1002/biot.201600441
  • Hoffmann A, Fallmann J, Mörl M, Stadler PF, Amman F. Accurate Mapping of tRNA Reads. Bioinformatics. 2017 [Epub ahead of print]. dx.doi.org/10.1093/bioinformatics/btx756
  • Hoffmann M, Schwertassek U, Seydel A, Weber K, Falk W, Hauschildt S, Lehmann J. A refined and translationally relevant model of chronic DSS colitis in BALB/c mice. Lab Anim. 2017 [Epub ahead of print]. dx.doi.org/10.1177/0023677217742681
  • Hoffmann M, Schwertassek U, Seydel A, Weber K, Hauschildt S, Lehmann J. Therapeutic efficacy of a combined sage and bitter apple phytopharmaceutical in chronic DSS-induced colitis. Scientific Reports. 7 (2017), 1, Art. 14214, 10 S.dx.doi.org/10.1038/s41598-017-13985-x
  • Hoffmann T, Meyer A, Heiser U, Kurat S, Böhme L, Kleinschmidt M, Bühring KU, Hutter-Paier B, Farcher M, Demuth HU, Lues I, Schilling, S. Glutaminyl cyclase inhibitor PQ912 improves cognition in mouse models of Alzheimer‘s disease - studies on relation to effective target occupancy. The journal of pharmacology and experimental therapeutics 362 (2017), 1, S. 119-130. dx.doi.org/10.1124/jpet.117.240614
  • Holden E, Tárnok A, Popescu G. Quantitative phase imaging for label-free cytometry. Cytometry. Part A 91 (2017), 5, S. 407-411. dx.doi.org/10.1002/cyto.a.23130
  • Indrischek H, Prohaska SJ, Gurevich VV, Gurevich EV, Stadler PF. Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes. BMC Evol Biol. 17 (2017), 163, 22 S. dx.doi.org/10.1186/s12862-017-1001-4
  • Jaimes Y, Naaldijk Y, Wenk K, Leovsky C, Emmrich F. Mesenchymal Stem Cell-Derived Microvesicles Modulate Lipopolysaccharides-Induced Inflammatory Responses to Microglia Cells. Stem Cells. 35 (2017), 3, S. 812-823. dx.doi.org/10.1002/stem.2541
  • Johnson AA, Naaldijk Y, Hohaus C, Meisel HJ, Krystel I, Stolzing A. Protective effects of alpha phenyl-tert-butyl nitrone and ascorbic acid in human adipose derived mesenchymal stem cells from differently aged donors. Aging 9 (2017), 2, S. 340-352. dx.doi.org/10.18632/aging.101035
  • Jung SH, Lee HJ, Lee YK, Yang DH, Kim HJ, Rhee JH, Emmrich F, Lee JJ. A phase I clinical study of autologous dendritic cell therapy in patients with relapsed or refractory multiple myeloma. Oncotarget. 8 (2017), S. 41538-41548. dx.doi.org/10.18632/oncotarget.14582
  • Kehlen A, Haegele M, Böhme L, Cynis H, Hoffmann T, Demuth HU. N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity. Bioscience Reports, 37 (2017), 4, Art.BSR20170712, 14 S. dx.doi.org/10.1042/BSR20170712 
  • Kim TH, Tyndel MS, Zhang Z, Ahn J, Choi S, Szardenings M, Lipton J, Kim HJ, Hwan DKD. Exome sequencing reveals DNMT3A and ASXL1 variants associate with progression of chronic myeloid leukemia after tyrosine kinase inhibitor therapy. Leukemia research 59 (2017), S. 142-148. dx.doi.org/10.1016/j.leukres.2017.06.009 
  • Kolora SR, Faria R, Weigert A, Schaffer S, Grimm A, Henle K, Sahyoun AH, Stadler PF, Nowick K, Bleidorn C, Schlegel M. The complete mitochondrial genome of Lacerta bilineata and comparison with its closely related congener L. Viridis. Mitochondrial DNA 28 (2017), Nr. 1, S. 116-118. dx.doi.org/10.3109/19401736.2015.1111349
  • Kubitschke H, Schnauß J, Nnetu KD, Warmt E, Stange R, Käs JA. Actin and microtubule networks contribute differently to cell response for small and large strains. New Journal of Physics, 19 (2017, 093003. dx.doi.org/10.1088/1367-2630/aa7658
  • Kunath J, Delaroque N, Szardenings M, Neundorf I, Straub RH. Sympathetic nerve repulsion inhibited by designer molecules in vitro and role in experimental arthritis. Life sciences 168 (2017), S. 47-53. dx.doi.org/10.1016/j.lfs.2016.11.009
  • Laux EM, Bier FF, Hölzel R. Electrode-based  AC electrokinetics of proteins: A mini-review. Bioelectrochemistry. 120 (2018), S. 76-82. dx.doi.org/10.1016/j.bioelechem.2017.11.010
  • Lepik K, Annilo T, Kukuškina V; eQTLGen Consortium, Kisand K, Kutalik Z, Peterson P, Peterson H. C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis. PLoS Computional biology. 13 (2017), 9, Art. E1005766, 20 S. dx.doi.org/10.1371/journal.pcbi.1005766
  • Leven M, Knaab TC, Held J, Duffy S, Meister S, Fischli C, Meitzner D, Lehmann U, Lungerich B, Kuna K, Stahlke P, Delves MJ, Buchholz M, Winzeler EA, Avery VM, Mordmüller B, Wittlin S, Kurz T. 3-Hydroxy-N‘-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of Medicinal Chemistry, 60 (2017), 14, S. 6036-6044. dx.doi.org/10.1021/acs.jmedchem.7b00140
  • Lindner S, Gruhle K, Schmidt R, Garamus VM, Ramsbeck D, Hause G, Meister A, Sinz A, Drescher S. Azide-modified membrane lipids: Synthesis, properties, and reactivity. Langmuir, 33 (2017), 20, S. 4960-4973. dx.doi.org/10.1021/acs.langmuir.7b00228
  • Lukowski SW, Lloyd-Jones LR, Holloway A, Kirsten H, Hemani G, Yang J, Small K, Zhao J, Metspalu A, Dermitzakis ET, Gibson G, Spector TD, Thiery J, Scholz M, Montgomery GW, Esko T, Visscher PM, Powell JE. Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood. Nature Communications. 8 (2017), Art. 483, 10 S. dx.doi.org/10.1038/s41467-017-00473-z
  • Machné R, Murray DB, Stadler PF. Similarity-Based Segmentation of Multi-Dimensional Signals. Scientific Reports. 7 (2017), 12355, 11 S. dx.doi.org/10.1038/s41598-017-12401-8
  • Meinlschmidt P, Brode V, Sevenich R, Ueberham E, Schweiggert-Weisz U, Lehmann J, Rauh C, Knorr D, Eisner, P. High pressure processing assisted enzymatic hydrolysis - An innovative approach for the reduction of soy immunoreactivity. Innovative food science & emerging technologies 40 (2017), S. 58-67. dx.doi.org/10.1016/j.ifset.2016.06.022 
  • Moreira-Soto A, Sarno M, Pedroso C, Netto EM, Rockstroh A, Luz E, Feldmann M, Fischer C, Bastos FA, Kümmerer BM, de Lamballerie X, Drosten C, Ulbert S, Brites C, Drexler JF. Evidence for congenital Zika virus infection from neutralizing antibody titers in maternal sera, Northeastern Brazil. The journal of infectious diseases. 216 (2017), 12, S. 1501-1504. dx.doi.org/10.1093/infdis/jix539 
  • Müller B, Schaadt G, Boltze J, Emmrich F; LEGASCREEN Consortium, Skeide MA, Neef NE, Kraft I, Brauer J, Friederici AD, Kirsten H, Wilcke A.  ATP2C2 and DYX1C1 are  putative modulators of  dyslexia-related MMR. Brain Behavior. 7 (2017), 11, e00851. dx.doi.org/10.1002/brb3.851
  • Naaldijk Y, Jäger C, Fabian C, Leovsky C, Blüher A, Rudolph L, Hinze A, Stolzing A. Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice. Neuropathology and applied neurobiology 43 (2017), 4, S. 299-314. dx.doi.org/10.1111/nan.12319
  • Namasu CY, Katzerke C, Bräuer-Hartmann D, Wurm AA, Gerloff D, Hartmann JU, Schwind S, Müller-Tidow C, Hilger N, Fricke S, Christopeit M, Niederwieser D, Behre G. ABR, a novel inducer of transcription factor C/EBPα, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia. Oncotarget. 8 (2017), 61, S. 103626-103639. dx.doi.org/10.18632/oncotarget.22093
  • Neel NE, Müller B, Liebig J, Schaadt G, Grigutsch M, Gunter TC, Wilcke A, Kirsten H, Skeide MA, Kraft I, Kraus N, Emmrich F, Brauer J, Boltze J, Friederici AD. Dyslexia risk gene relates to representation of sound in the auditory brainstem. Developmental cognitive neuroscience 24 (2017), S. 63-71. dx.doi.org/10.1016/j.dcn.2017.01.008
  • Netto EM, Moreira-Soto A, Pedroso C, Höser C, Funk S, Kucharski AJ, Rockstroh A, Kümmerer BM, Sampaio GS, Luz E, Vaz SN, Dias JP, Bastos FA, Cabral R, Kistemann T, Ulbert S, de Lamballerie X, Jaenisch T, Brady OJ, Drosten C, Sarno M, Brites C, Drexler JF. High Zika Virus Seroprevalence in Salvador, Northeastern Brazil limits the potential for further outbreaks. MBio. 8 (2017), 6, Art. E01390-17. dx.doi.org/10.1128/mBio.01390-17
  • Nitzsche F, Müller C, Lukomska B, Jolkkonen J, Deten A, Boltze J. The MSC adhesion cascade - insights into homing and transendothelial migration. Stem Cells. 35 (2017), 6, S. 1446-1460. dx.doi.org/10.1002/stem.2614
  • Nowakowski A, Andrzejewska A, Boltze J, Nitzsche F, Cui LL, Jolkkonen J, Walczak P, Lukomska B, Janowski M. Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells. Scientific Reports 7 (2017), Art. 1103, 12 S. dx.doi.org/10.1038/s41598-017-01304-3
  • Oberbach A, Schlichting N, Feder S, Lehmann S, Kullnick Y, Buschmann T, Blumert C, Horn F, Neuhaus J, Neujahr R, Bagaev E, Hagl C, Pichlmaier M, Rodloff AC, Gräber S, Kirsch K, Sandri M, Kumbhari V, Behzadi A, Behzadi A, Correia JC, Mohr FW, Friedrich M. New insights into valve-related intramural and intracellular bacterial diversity in infective endocarditis. PLoS one. 12 (2017), 4, Art. e0175569, 20 S. dx.doi.org/10.1371/journal.pone.0175569
  • Oberbach A, Schlichting N, Heinrich M, Kullnick Y, Retschlag U, Lehmann S, Khashab MA, Kalloo AN, Kumbhari V. Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism in obese rats. Gastrointestinal endoscopy. 87 (2018), 1, S. 288-299.e6. dx.doi.org/10.1016/j.gie.2017.04.038 
  • Oswald L, Grosser S, Smith DM, Kaes JA. Jamming transitions in cancer. Journal of Physics D: Applied Physics. 50 (2017), 48, Art. 483001. dx.doi.org/10.1088/1361-6463/aa8e83 
  • Piechotta A, Parthier C, Kleinschmidt M, Gnoth K, Pillot T, Lues I, Demuth HU, Schilling S, Rahfeld JU, Stubbs M. Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy. Journal of biological chemistry. 292 (2017), S. 12713-12724. dx.doi.org/10.1074/jbc.M117.777839 
  • Pott J, Burkhardt R, Beutner F, Horn K, Teren A, Kirsten H, Holdt LM, Schuler G, Teupser D, Loeffler M, Thiery J, Scholz M. Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery. Atherosclerosis. 259 (2017), S. 32-40. dx.doi.org/10.1016/j.atherosclerosis.2017.02.018
  • Prohaska SJ, Berkemer SJ, Gärtner F, Gatter T, Retzlaff N; Students of the Graphs and Biological Networks Lab 2017, Höner Zu Siederdissen C, Stadler PF. Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem. J Math Biol. 2017 Dec 19. http://dx.doi.org/10.1007/s00285-017-1197-3
  • Przybylski S, Gasch M, Marschner A, Ebert M, Ewe A, Helmig G, Hilger N, Fricke S, Rudzok S, Aigner A, Burkhardt J. Influence of nanoparticle-mediated transfection on proliferation of primary immune cells in vitro and in vivo. PLoS one. 12 (2017), 5, Art. e0176517, 16 S. dx.doi.org/10.1371/journal.pone.0176517
  • Ramsbeck D, Hamann A, Schlenzig D, Schilling S, Buchholz M. First insight into structure-activity relationships of selective Meprin ß inhibitors. Bioorganic & Medicinal Chemistry Letters. 27 (2017), 11, S. 2428-2431. dx.doi.org/10.1016/j.bmcl.2017.04.012
  • Rockstroh A, Moges B, Barzon L, Sinigaglia A, Palù G, Kumbukgolla W, Schmidt-Chanasit J, Sarno M, Brites C, Moreira-Soto A, Drexler JF, Ferreira OC, Ulbert S. Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop. Emerging microbes and infections. 6 (2017), Art. E99, 9 S. dx.doi.org/10.1038/emi.2017.87
  • Rodewohl A, Scholbach J, Leichsenring A, Köberle M, Lange F. Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. Innate immunity. 23 (2017), 3, S. 258-275. dx.doi.org/10.1177/1753425917690814
  • Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. (2017), gutjnl-2017-314454. dx.doi.org/10.1136/gutjnl-2017-314454
  • Sajfutdinow M, Uhlig K, Prager A, Schneider C, Abel B, Smith DM. Nanoscale patterning of self-assembled monolayer (SAM)-functionalised substrates with singlemolecule contact printing. Nanoscale. 39 (2017), 9, S. 15098-15106. dx.doi.org/10.1039/C7NR03696E
  • Sandetskaya N, Moos D, Pötter H, Seifert S, Jenerowicz M, Becker H, Zilch C, Kuhlmeier D. An integrated versatile lab-on-a-chip platform for the isolation and nucleic acid-based detection of pathogens. Future Science OA 3 (2017), 2, Art. FSO177, 13 S. dx.doi.org/10.4155/fsoa-2016-0088
  • Schnauß J, Glaser M, Lorenz JS, Schuldt C, Möser C, Sajfutdinow M, Haendler T, Kaes JA, Smith DM. DNA nanotubes as a versatile tool to study semiflexible polymers. Journal of Visualized Experiments JoVE. (2017), 128. dx.doi.org/10.3791/56056 
  • Schneevoigt J, Fabian C, Leovsky C, Seeger J, Bahramsoltani M. In vitro expression of the extracellular matrix components aggrecan, collagen types I and II by articular cartilage-derived chondrocytes. Anatomia, histologia, embryologia 46 (2017), 1, S. 43-50. dx.doi.org/10.1111/ahe.12230
  • Schüttler A, Reiche K, Altenburger R, Busch W. The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis. Toxicological Sciences. 157 (2017), 2, S. 291-304. dx.doi.org/10.1093/toxsci/kfx045
  • Sonnabend A, Spahn V, Stech M, Zemella A, Stein C, Kubick S. Production of G protein-coupled receptors in an insect-based cell-free system. Biotechnology and bioengineering. 114 (2017), 10, S. 2328–2338. dx.doi.org/10.1002/bit.26346
  • Soria J, Acera A, Merayo-LLoves J, Durán JA, González N, Rodriguez S, Bistolas N, Schumacher S, Bier FF, Peter H, Stöcklein W, Suárez T. Tear proteome analysis in ocular surface diseases using label-free LC-MS/MS and multiplexed-microarray biomarker validation. Scientific Reports. 7 (2017), Art. 17478, 15 S. . http://dx.doi.org/10.1038/s41598-017-17536-2
  • Spahn C, Wermann M, Eichentopf R, Hause G, Schlenzig D, Schilling S. Purification of recombinant Aβ(1-42) and pGlu-Aβ(3-42) using preparative SDS-PAGE. Electrophoresis 38 (2017), 16, S. 2042-2049. dx.doi.org/10.1002/elps.201700154
  • Stamenković S, Dučić T, Stamenković V, Kranz A, Andjus PR. Imaging of glial cell morphology, SOD1 distribution and elemental composition in the brainstem and hippocampus of the ALS hSOD1G93A rat. Neuroscience 357 (2017), S. 37-55. dx.doi.org/10.1016/j.neuroscience.2017.05.041
  • Stech M, Nikolaeva O, Thoring L, Stöcklein WFM, Wüstenhagen DA, Hust M, Dübel S, Kubick S. Cell-free synthesis of functional antibodies using a coupled in vitro transcription-Translation system based on CHO cell lysates. Scientific Reports. 7 (2017), Art. 12030, 15 S. dx.doi.org/10.1038/s41598-017-12364-w
  • Stephan A, Hahn-Löbmann S, Rosche F, Buchholz M, Giritch A, Gleba Y. Simple purification of Nicotiana benthamiana-produced recombinant colicins: High-yield recovery of purified proteins with minimum alkaloid content supports the suitability of the host for manufacturing food additives. International Journal of Molecular Sciences. 19 (2017). 1, Art. 95, 13 S. dx.doi.org/10.3390/ijms19010095
  • Strehle D, Mollenkopf P, Glaser M, Golde T, Schuldt C, Käs JA, Schnauß J. Single actin bundle rheology. Molecules. 22 (2017), 10, Art. 1804, 12 S. dx.doi.org/10.3390/molecules22101804 
  • Teren A, Kirsten H, Beutner F, Scholz M, Holdt LM, Teupser D, Gutberlet M, Thiery J, Schuler G, Eitel, I. Alteration of multiple leukocyte gene expression networks is linked with magnetic resonance markers of prognosis after acute ST-Elevation myocardial infarction. Scientific Reports 7 (2017), Art. 41705, 10 S. dx.doi.org/10.1038/srep41705
  • Thalheim T, Quaas M, Herberg M, Braumann UD, Kerner C, Loeffler M, Aust G, Galle J. Linking stem cell function and growth pattern of intestinal organoids. Developmental Biology. 433 (2018), 2, S. 254-261. dx.doi.org/10.1016/j.ydbio.2017.10.013 
  • Theuß T, Ueberham E, Lehmann J, Lindner T, Springer S. Immunogenic potential of a Salmonella Typhimurium live vaccine for pigs against monophasic Salmonella Typhimurium DT 193. BMC Vetinary Research. 13 (2017), 1, Art. 343, 8 S. dx.doi.org/10.1186/s12917-017-1271-5
  • Thoring L, Dondapati SK, Stech M. High-yield production of »difficult-to-express« proteins in a continuous exchange cell-free system based on CHO cell lysates. Scientific Reports. 7 (2017), Art, 11710. dx.doi.org/10.1038/s41598-017-12188-8
  • Valach M, Moreira S, Hoffmann S, Stadler PF, Burger G. Keeping it complicated: Mitochondrial genome plasticity across diplonemids. Scientific Reports. 7 (2017), 1, 14166, 12 S. dx.doi.org/10.1038/s41598-017-14286-z
  • Wurm AA, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer-Hartmann D, Katzerke C, Hartmann JU, Benoukraf T, Fricke S, Hilger N, Müller AM, Bill M, Schwind S, Tenen DG, Niederwieser D, Alberich-Jorda M, Behre G. Disruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation. Nature Communications. 8 (2017), Art. 46. 16 S. dx.doi.org/10.1038/s41467-017-00032-6
  • Zemella A, Grossmann S, Sachse R, Sonnabend A, Schaefer M, Kubick S. Qualifying a eukaryotic cell-free system for fluorescence based GPCR analyses. Scientific Reports 7 (2017), Art. 3740, 10 S. dx.doi.org/10.1038/s41598-017-03955-8

 

Publications 2016

  • Bader D, Klier DT, Hettrich C, Bier FF, Wessig P. Detecting carbohydrate–lectin interactions using a fluorescent probe based on DBD dyes. Anal. Methods. 2016 Jan 13; 8, 1235-1238: DOI dx.doi.org/10.1039/C5AY02991K
  • Bavli D, Prill S, Ezra E, Levy G, Cohen M, Vinken M, Vanfleteren J, Jaeger M, Nahmias Y. Real-time monitor­ing of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction. Proceedings of the National Academy of Sciences of the United States of America : PNAS. 113 (2016), 16, S. E2231-E2240. dx.doi.org/10.1073/pnas.1522556113
  • Becker A, Eichentopf R, Sedlmeier R, Cynis H, Koch B, Stephan A, Bäuscher Ch, Kohlmann S, Hoffmann T, Kehlen A, Berg S, Freyse EJ, Osmand A, von Hörsten St, Graubner S, Demuth HU, Schilling S. IsoQC (QPCTL) knock out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes. Biological Chemistry. 397 (2016), 1, S. 45-55. dx.doi.org/10.1515/hsz-2015-0192
  • Boltze J, Wagner DC, Barthel H, Gounis M. Academic-industry collaborations in translational stroke research. Translational Stroke Research. 7 (2016), 4, S. 343-353. dx.doi.org/10.1007/s12975-016-0475-5
  • Boltze J, Ayata C. Challenges and controversies in transla­tional stroke research : An introduction. Editorial. Translational Stroke Research. 7 (2016), 5, S. 355-357. dx.doi.org/10.1007/s12975-016-0492-4
  • Boltze J, Wagner DC, Henninger N, Plesnila N, Ayata C. Phase III preclinical trials in translational stroke research : community response on framework and guidelines. Translational Stroke Research. 7 (2016), 4, S. 241-247. dx.doi.org/10.1007/s12975-016-0474-6
  • Brameshuber M, Sevcsik E, Rossboth BK, Manner C, Deigner HP, Peksel B, Péter M, Török Z, Hermetter A, Schütz GJ. Oxidized phospholipids inhibit the formation of cholesterol-dependent plasma membrane nano­platforms. Biophysical journal. 110 (2016), 1, S. 205-213. dx.doi.org/10.1016/j.bpj.2015.11.018
  • Canzler S, Stadler PF, Hertel J. U6 snRNA intron insertion occurred multiple times during fungi evolution. RNA biology. 13 (2016), 2, S. 119-127. dx.doi.org/10.1080/15476286.2015.1132139
  • Connor DO, Zantow J, Hust M, Bier FF, von Nickisch-Rosenegk M. Identification of novel immunogenic proteins of Neisseria gonorrhoeae by phage display. PLoS One. 11 (2016), Nr. 2, Art. e0148986, 24 S. dx.doi.org/10.1371/journal.pone.0148986
  • Corrales Ureña YR, Lisboa-Filho PN, Szardenings M, Gätjen L, Noeske, P LM, Rischka K. Formation and composition of adsorbates on hydro­phobic carbon surfaces from aqueous laccase-maltodextrin mixture suspension. Applied surface science. 385 (2016), S. 216-224. dx.doi.org/10.1016/j.apsusc.2016.05.097
  • Couturier J-P, Wischerhoff E, Benin R, Hettrich C, Koetz J, Sütterlin M, Tiersch B, Laschewsky A. Thermoresponsive Polymers and Inverse Opal Hydrogels for the Detection of Diols. Langmuir. 32 (2016) 4333-4345: DOI dx.doi.org/10.1021/acs.langmuir.6b00803
  • Cui LL, Kinnunen T, Boltze J, Nystedt J, Jolkkonen J. Clump­ing and viability of bone marrow derived mesen­chymal stromal cells under different preparation procedures : A flow cytometry-based in vitro study. Stem Cells International. (2016), Art. 1764938, 8 S. dx.doi.org/10.1155/2016/1764938
  • Cynis H, Frost JL, Crehan H, Lemere CA. Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges. Molecular neurodegeneration. 11 (2016), Art. 48, 11 S. dx.doi.org/10.1186/s13024-016-0115-2
  • Domin G, Findeiß S, Wachsmuth M, Will S, Stadler PF, Mörl M. Applicability of a computational design approach for synthetic riboswitches. Nucleic Acids Research, 2016 Dec 19, pii: gkw1267. (Epub ahead of print]. dx.doi.org/10.1093/nar/gkw1267
  • Ewe A, Przybylski S, Burkhardt J, Janke A, Appelhans D, Aigner A. A novel tyrosine-modified low molecular weight polyethylenimine (P10Y) for efficient siRNA delivery in vitro and in vivo. J Control Release. 2016 May 28;230:13-25. DOI dx.doi.org/10.1016/j.jconrel.2016.03.034. Epub 2016 Apr 7.
  • Feoktistova N, Rose J, Prokopović VZ, Vikulina AS, Skirtach A, Volodkin D. Controlling the vaterite CaCO3 crystal pores : Design of tailor-made polymer based microcapsules by hard templating. Langmuir. The ACS journal of surfaces and colloids. 32 (2016), 17, S. 4229-4238. dx.doi.org/10.1021/acs.langmuir.6b00717
  • Fertey J, Bayer L, Grunwald T, Pohl A, Beckmann J, Gotzmann G, Casado JP, Schönfelder J, Rögner FH, Wetzel C, Thoma M, Bailer SM, Hiller E, Rupp S, Ulbert S. Pathogens Inactivated by Low-Energy-Electron Irradiation Maintain Antigenic Properties and Induce Protective Immune Responses. Viruses. 2016 Nov 23;8(11). pii: E319.
  • Flemmig J, Schwarz P, Bäcker I, Leichsenring A, Lange F, Arnhold J. Fast and Specific Assessment of the Halogenating Peroxidase Activity in Leukocyte-enriched Blood Samples. J. Vis. Exp. (2016), e54484, View video paper
  • Georgi V, Georgi L, Blechert M, Bergmeister M, Zwanzig M, Wüstenhagen DA, Bier FF, Jung E, Kubick S. On-chip automation of cell-free protein synthesis: new opportunities due to a novel reaction mode. Lab Chip. 2016 Jan 5;16(2):269-81. DOI dx.doi.org/10.1039/c5lc00700c.
  • Glaser M, Schnauß J, Tschirner T, Schmidt S, Moebius-Winkler M, Käs J, Smith DM. Self-assembly of hierarchically ordered structures in DNA nanotube systems. New journal of physics. 18 (2016), Art. 055001, 14 S. dx.doi.org/10.1088/1367-2630/18/5/055001
  • Habaza M, Kirschbaum M, Guernth-Marschner C, Dardikman G, Barnea I, Korenstein R, Duschl C, Shaked NT. Rapid 3D refractive-index imaging of live cells in suspension without labeling using dielectro­phoretic cell rotation. Advanced Science. (2016), 1600205, 9 S. dx.doi.org/10.1002/advs.201600205
  • Haid S, Grethe C, Bankwitz D, Grunwald T, Pietschmann T. Identification of a human respiratory syncytial virus cell entry inhibitor by using a novel lentiviral pseudotype system. Journal of virology. 90 (2016), Nr. 6, S. 3065-3073. dx.doi.org/10.1128/JVI.03074-15
  • Hamidouche Z, Rother K, Przybilla J, Krinner A, Clay D, Hopp L, Fabian C, Stolzing A, Binder H, Charbord P, Galle J. Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity. Stem Cells. 2016 Oct 13. [Epub ahead of print]. dx.doi.org/10.1002/stem.2514
  • Heathman TR, Stolzing A, Fabian C, Rafiq QA, Coopman K, Nienow AW, Kara B, Hewitt CJ. Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate. Cytotherapy. 18 (2016), 4, S. 523-535. dx.doi.org/10.1016/j.jcyt.2016.01.007
  • Hezaveh K, Kloetgen A, Bernhart SH, Mahapatra KD, Lenze D, Richter J, Haake A, Bergmann AK, Brors B, Burkhardt B, Claviez A, Drexler HG, Eils R, Haas S, Hoffmann S, Karsch D, Klapper W, Kleinheinz K, Korbel J, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Leich E, Loeffler M, Mantovani-Loeffler L, López C, McHardy AC, Möller P, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schlesner M, Scholz I, Stadler PF, Stilgenbauer S, Sungalee S, Szczepanowski M, Trümper L, Weniger MA, Siebert R, Borkhardt A, Hummel M, Hoell JI; ICGC MMML-Seq Project group. Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis. Haematologica. 101 (2016), 11, S. 1380-1389. dx.doi.org/10.3324/haematol.2016.143891
  • Hielscher-Michael S, Griehl C, Buchholz M, Demuth HU, Arnold N, Wessjohann LA. Natural products from microalgae with potential against Alzheimer’s disease: sulfolipids are potent glutaminyl cyclase inhibitors. Mar Drugs. 2016 Nov 2;14(11). pii: E203. dx.doi.org/10.3390/md14110203
  • Hilger N, Glaser J, Müller C, Halbich C, Müller A, Schwertassek U, Lehmann J, Ruschpler P, Lange F, Boldt A, Stahl L, Sack U, Oelkrug C, Emmrich F, Fricke S. Attenua­tion of graft-versus-host-disease in NOD scid IL-2Rγ-/- (NSG) mice by ex vivo modulation of human CD4+ T cells. Cytometry Part A. 89 (2016), 9, S. 803 - 817. dx.doi.org/10.1002/cyto.a.22930
  • Hill K, Fiorito S, Taddeo VA, Schulze A, Leonhardt M, Epifano F, Genovese S. Plumbagin, Juglone, and Boropinal as novel TRPA1 agonists. Journal of natural products. 79 (2016), 4, S .697-703. dx.doi.org/10.1021/acs.jnatprod.5b00396
  • Indrischek H, Wieseke N, Stadler PF, Prohaska SJ. The paralog-to-contig assignment problem : high quality gene models from fragmented assemblies. Algorithms for molecular biology. 11 (2016), Art. 1, 14 S. dx.doi.org/10.1186/s13015-016-0063-y
  • Jaimes Y, Naaldijk Y, Wenk K, Leovsky C, Emmrich F. Mesenchymal stem cell-derived microvesicles modulate LPS-induced inflammatory responses to microglia cells. StemCells. 2016 Nov 16. dx.doi.org/10.1002/stem.2541
  • Jorjani H, Kehr S, Jedlinski DJ, Gumienny R, Hertel J, Stadler PF, Zavolan M, Gruber AR. An updated human snoRNAome. Nucleic Acids Research. 44 (2016), 11, S. 5068-5082. dx.doi.org/10.1093/nar/gkw386
  • Jühling F, Kretzmer H, Bernhart SH, Otto C, Stadler PF, Hoffmann S. Metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data. Genome research. 26 (2016), 2, S. 256-262. dx.doi.org/10.1101/gr.196394.115
  • Kalkhof S, Schildbach S, Blumert C, Horn F, von Bergen M, Labudde D.  PIPINO: A software package to facilitate the identification of protein-protein inter­actions from affinity purification mass spectrometry data. BioMed research international. (2016), Art. 2891918, 13 S. dx.doi.org/10.1155/2016/2891918
  • Kang MG, Kim YN, Lee JH, Szardenings M, Baek HJ, Kook H, Kim HR, Shin MG. Clinicopathological implications of mitochondrial genome alterations in pediatric acute myeloid leukemia. Annals of laboratory medicine. 36 (2016), 2, S. 101-110. dx.doi.org/10.3343/alm.2016.36.2.101
  • Keller KC, Ding H, Tieu R, Sparks NR, Ehnes DD, Zur Nieden N. Wnt5a supports osteogenic lineage decisions in embryonic stem cells. Stem cells and development. 25 (2016), 13, S. 1020-1032. dx.doi.org/10.1089/scd.2015.0367
  • Kleinschmidt M, Schoenfeld R, Göttlich C, Bittner D, Metzner JE, Leplow B, Demuth HU. Characterizing aging, mild cognitive impairment, and Dementia with blood-based biomarkers and neuropsychology. Journal of Alzheimer‘s disease. 50 (2016), 1, S. 111-26. dx.doi.org/10.3233/JAD-143189
  • Kraft I, Schreiber J, Cafiero R, Metere R, Schaadt G, Brauer J, Neef NE, Müller B, Kirsten H, Wilcke A, Boltze J, Friederici AD, Skeide MA. Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI. Neuroimage. 143 (2016), S. 378-386. dx.doi.org/10.1016/j.neuroimage.2016.09.004
  • Krakauer DC, Müller L, Prohaska SJ, Stadler PF. Design specifications for cellular regulation. Theory in biosciences. 135 (2016), 4, S. 231-240. dx.doi.org/10.1007/s12064-016-0239-5
  • Kucharík M, Hofacker IL, Stadler PF, Qin J. Pseudoknots in RNA folding landscapes. Bioinformatics. 32 (2016), 2, S. 187-194. dx.doi.org/10.1093/bioinformatics/btv572
  • Laube M, Stolzing A, Thome UH, Fabian C. Therapeutic potential of mesenchymal stem cells for pulmonary complications associated with preterm birth. The inter­national journal of biochemistry & cell biology. 74 (2016), S. 18-32. dx.doi.org/10.1016/j.biocel.2016.02.023
  • Laux EM, Knigge X, Bier FF, Wenger C, Hölzel R. Aligned immobilization of proteins using AC electric fields. Small. 12 (2016), 11, S. 1514-1520. dx.doi.org/10.1002/smll.201503052
  • Leichsenring A, Bäcker I, Furtmüller PG, Obinger C, Lange F, Flemmig J. Long-term effects of (-)-Epigallocatechin Gallate (EGCG) on Pristane-Induced Arthritis (PIA) in female dark agouti rats. PLoS one. 11 (2016), 3, Art. e0152518, 27 S. dx.doi.org/10.1371/journal.pone.0152518
  • Leontyev S, Davierwala PM, Krögh G, Feder S, Oberbach A, Bakhtiary F, Misfeld M, Borger MA, Mohr FW. Early and late outcomes of complex aortic root surgery in patients with aortic root abscesses†. Eur J Cardiothorac Surg. 2016 Feb;49(2):447-55.
  • Lipka J, Semmler-Behnke M, Wenk A, Burkhardt J, Aigner A, Kreyling W. Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments. Data in Brief 7 (2016), pp.1175-1178. DOI dx.doi.org/10.1016/j.dib.2016.03.092
  • Lipka J, Semmler-Behnke M, Wenk A, Burkhardt J, Aigner A, Kreyling W. Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice. Int J Pharm. 2016 Mar 16;500(1-2):227-35. DOI dx.doi.org/10.1016/j.ijpharm.2016.01.038. Epub 2016 Jan 21.
  • Lipka J, Semmler-Behnke M, Wenk A, Burkhardt J, Aigner A, Kreyling W. Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments. Data in Brief. 7 (2016), S. 1175-1178. dx.doi.org/10.1016/j.dib.2016.03.092
  • Lohmann G, Stelzer J, Zuber V, Buschmann T, Margulies D, Bartels A, Scheffler K. Task-related edge density (TED) - a new method for revealing dynamic network formation in fMRI data of the human brain. PLoS One. 11 (2016), 6, Art. e0158185, 22 S. dx.doi.org/10.1371/journal.pone.0158185
  • Lorenz R, Hofacker IL, Stadler PF. RNA folding with hard and soft constraints. Algorithms for molecular biology.  11(2016), Art. 8, 13 S. dx.doi.org/10.1186/s13015-016-0070-z
  • Makert GR, Vorbrüggen S, Krautwald-Junghanns ME, Voss M, Sohn K, Buschmann T, Ulbert S. A method to identify protein antigens of Dermanyssus gallinae for the protection of birds from poultry mites. Parasitol Res. 2016 Jul;115(7):2705-13. DOI dx.doi.org/10.1007/s00436-016-5017-2
  • Meinlschmidt P, Ueberham E, Lehmann J, Schweiggert-Weisz U, Eisner P. Immunoreactivity, sensory and physicochemical properties of fermented soy protein isolate. Food chemistry. 205 (2016), S. 229-238. dx.doi.org/10.1016/j.foodchem.2016.03.016
  • Memczak H, Lauster D, Kar P, Di Lella S, Volkmer R, Knecht V, Herrmann A, Ehrentreich-Förster E, Bier FF, Stöcklein WF. Anti-hemag­glutinin antibody derived lead peptides for inhibitors of influenza virus binding. PLoS One. 11 (2016), 7, Art. e0159074, 24 S. dx.doi.org/10.1371/journal.pone.0159074
  • Menger M, Yarman A, Erdőssy J, Yildiz HB, Gyurcsányi RE, Scheller FW. MIPs and Aptamers for Recognition of Proteins in Biomimetic Sensing. Biosensors (Basel). 2016 Jul 18;6(3). pii: E35. DOI dx.doi.org/10.3390/bios6030035Article
  • Min-Gu K, Hyun-Woo C, Jun Hyung L, Yong Jun C, Hyun-Jung C, Jong-Hee S, Soon-Pal S, Szardenings M, Hye-Ran K, Myung-Geun S. Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemia. OncoTarget. 7 (2016), 35, S. 57036-57049. dx.doi.org/10.18632/oncotarget.10958
  • Morschheuser L, Mükusch S, Riedner M, Seitz H, Rohn S. High-performance thin-layer chromatography as a fast screening tool for phosphorylat­ed peptides. Journal of chromatography B: Analytical technologies in the biomedical and life sciences. 1008 (2016), S. 198-205. dx.doi.org/10.1016/j.jchromb.2015.11.055
  • Müller B, Wilcke A, Boulesteix AL, Brauer J, Passarge E, Boltze J, Kirsten H. Improved prediction of complex diseases by common genetic markers: State of the art and further perspectives. Human genetics. 135 (2016), 3, S. 259-272. dx.doi.org/10.1007/s00439-016-1636-z
  • Müller B, Wilcke A, Czepezauer I, Ahnert P, Boltze J,  Kirsten H, Friederici AD, Emmrich F, Brauer J, Neef N, Skeide MA, Schaadt G, Kraft I, Dörr L. Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort. Scientific Report. 6 (2016), Art. 27901, 11 S. dx.doi.org/10.1038/srep27901
  • Naaldijk Y, Friedrich-Stöckigt A, Sethe S, Stolzing A. Com­parison of different cooling rates for fibroblast and keratinocyte cryopreserva­tion. Journal of tissue engineer­ing and regenaritive medicine. (2016), 10, S. E354 - E364. dx.doi.org/10.1002/term.1815
  • Naaldijk Y, Jager C, Fabian C, Leovsky C, Bluher A, Rudolph L, Hinze A, Stolzing A. Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1. Alzheimer mice. Neuropathology and applied neurobiology. 2016 Feb 26. [Epub ahead of print]. dx.doi.org/10.1111/nan.12319
  • Nitzsche B, Barthel H, Lobsien D, Boltze J, Zeisig V, Dreyer AY. Focal cerebral ischemia by permanent middle cerebral artery occlusion in sheep: Surgical technique, clinical imaging, and histopatho­logical results. Neuromethods. 116 (2016), S. 195 - 225. dx.doi.org/10.1007/978-1-4939-3730-1_15
  • Oberbach A, Adams V, Schlichting N, Heinrich M, Kullnick Y, Lehmann S, Lehmann S, Feder S, Correia JC, Mohr FW, Völker U, Jehmlich N. Proteome profiles of HDL particles of patients with chronic heart failure are associated with immune response and also include bacteria proteins. Clin Chim Acta. 2016 Jan 30;453:114-22. DOI dx.doi.org/10.1016/j.cca.2015.12.005
  • Park SH, Zheng JH, Nguyen VH, Jiang SN, Kim DY, Szardenings M, Min JH, Hong Y, Choy HE, Min JJ. RGD peptide cell-surface display enhances the targeting and therapeutic efficacy of attenuated Salmonella-mediated cancer therapy. Theranostics. 6 (2016), 10, S. 1672-82. dx.doi.org/10.7150/thno.16135
  • Patra Bhattacharya D, Canzler S, Kehr S, Hertel J, Grosse I, Stadler PF. Phylogenetic distribution of plant snoRNA families. BMC Genomics. 17 (2016), 1, 969. dx.doi.org/10.1186/s12864-016-3301-2
  • Peng L, Yarman A, Jetzschmann KJ, Jeoung JH, Schad D, Dobbek H, Wollenberger U, Scheller FW. Molecularly imprinted electropolymer for a hexameric heme protein with direct electron transfer and peroxide electrocatalysis. Sensors. 16 (2016), 3, Art. 272, 11 S. dx.doi.org/10.3390/s16030272
  • Pösel C, Möller K, Boltze J, Wagner DC, Weise G. Isolation and flow cytometric analysis of immune cells from the ischemic mouse brain. Journal of visualized experiments : JoVE. 108 (2016), Art. e53658, 8 S. dx.doi.org/10.3791/53658
  • Prashant P, Elangovan E, Hettrich C, Möller HH, Linker T. Synthesis of 2-Thiocarbohydrates and Their Binding to Concanavalin A. J. Org. Chem. 81 (2016) 8595–8603: DOI dx.doi.org/10.1021/acs.joc.6b00987
  • Prill S, Bavli D, Levy G, Ezra E, Schmälzlin E, Jaeger MS, Schwarz M, Duschl C, Cohen M, Nahmias Y. Real-time monitor­ing of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone. Archives of toxicology. 90 (2016), 5, S. 1181-1191. dx.doi.org/10.1007/s00204-015-1537-2
  • Prokopović VZ, Vikulina AS, Sustr D, Duschl C, Volodkin D. Biodegradation-resistant multilayers coated with gold Nnnoparticles : toward a tailor-made artificial extra­cellular matrix. ACS Applied materials and interfaces. 8 (2016), 37, S. 24345 - 24349. dx.doi.org/10.1021/acsami.6b10095
  • Quast RB, Ballion B, Stech M, Sonnabend A, Varga BR, Wüstenhagen DA, Kele P, Schiller SM, Kubick S. Cell-free synthesis of functional human epidermal growth factor receptor: Investigation of ligand-independent dimerization in Sf21 microsomal membranes using non-canonical amino acids. Sci Rep. 2016 Sep 27;6:34048. DOI dx.doi.org/10.1038/srep34048 Artikel
  • Quast RB, Sonnabend A, Stech M, Wüstenhagen DA, Kubick S. High-yield cell-free synthesis of human EGFR by IRES-mediated protein translation in a continuous exchange cell-free reaction format. Sci Rep. 2016 Jul 26;6:30399. DOI dx.doi.org/10.1038/srep30399Artikel
  • Rekers NV, Bajema IM, Mallat MJ, Petersen B, Anholts JD, Swings GM, van Miert PP, Kerkhoff C, Roth J, Popp D, van Groningen MC, Baeten D, Goemaere N, Kraaij MD, Zandbergen M, Heidt S, van Kooten C, de Fijter JW, Claas FH, Eikmans M. Beneficial immune effects of myeloid-related proteins in kidney transplant rejection. American journal of transplantation. 16 (2016), 5, S. 1441-1455. dx.doi.org/10.1111/ajt.13634
  • Restrepo G, Stadler PF. Assessing greenness of chemical reactions and synthesis plans through posetic landscapes. ACS sustainable chemistry & engineering. 4 (2016),  4, S. 2191-2199. dx.doi.org/10.1021/acssuschemeng.5b01649
  • Righetti F, Nuss AM, Twittenhoff C, Beele S, Urban K, Will S, Bernhart SH, Stadler PF, Dersch P, Narberhaus F. Temperature-responsive in vitro RNA structurome of Yersinia pseudotuberculosis. Proceedings of the National Academy of Sciences of the United States of America : PNAS. 113 (2016), 26, S. 7237-7242. dx.doi.org/10.1073/pnas.1523004113
  • Rohani L, Fabian C, Holland H, Naaldijk Y, Dressel R, Löffler-Wirth H, Binder H, Arnold A, Stolzing A. Generation of human induced pluripotent stem cells using non-synthetic mRNA. Stem cell research. 16 (2016), 3, S. 662-672. dx.doi.org/10.1016/j.scr.2016.03.008
  • Roshyara NR, Horn K, Kirsten H, Ahnert P, Scholz M. Comparing performance of modern genotype imputation methods in different ethnicities. Scientific Reports. 6 (2016), Art. 34386, 12 S. dx.doi.org/10.1038/srep34386
  • Sack U, Boldt A, Mallouk N, Gruber R, Krenn V, Berger-Depincé AE, Conrad K, Tarnok A, Lambert C, Reinhold D, Fricke S. Cellular analyses in the monitoring of autoimmune diseases. Autoimmunity reviews. 15 (2016), 9, S. 883-9. dx.doi.org/10.1016/j.autrev.2016.07.010
  • Sauer M, Altrichter J, Haubner C, Pertschy A, Wild T, Doß F, Mencke T, Thomsen M, Ehler J, Henschel J, Doß S, Koch S, Richter G, Nöldge-Schomburg G, Mitzner SR. Bioartificial therapy of sepsis : Changes of norepinephrine-dosage in patients and influence on dynamic and cell based liver tests during extracorporeal treatments. BioMed research international. (2016), Art. 7056492, 11 S. dx.doi.org/10.1155/2016/7056492
  • Schnauß J, Händler T, Käs JA. Semiflexible biopolymers in bundled arrangements. Polymers. 8 (2016), 8, Art. 274, 23 S. dx.doi.org/10.3390/polym8080274
  • Schuldt C, Schnauß J, Händler T, Glaser M, Lorenz J, Golde T, Käs JA, Smith DM. Tuning synthetic semiflexible networks by bending stiffness. Physical review letters. 117 (2016), 19, 5 S. dx.doi.org/10.1103/PhysRevLett.117.197801
  • Schumacher S, Seitz H. A novel immunoassay for quantitative drug abuse screening in serum. Journal of immunological methods. 436 (2016), S. 34-40. dx.doi.org/10.1016/j.jim.2016.06.004
  • Schumacher S, Seitz H. Quality control of antibodies for assay development. New Biotechnolog. 33 (2016), 5 Pt A, S. 544-50. dx.doi.org/10.1016/j.nbt.2016.02.001
  • Skeide MA, Kraft I, Müller B, Schaadt G, Neef NE, Brauer J, Wilcke A, Kirsten H, Boltze J, Friederici AD. NRSN1 associat­ed grey matter volume of the visual word form area reveals dyslexia before school. Brain. 139 (2016), 10,S. 2792-2803. dx.doi.org/10.1093/brain/aww153
  • Sombetzki M, Koslowski N, Doss S, Loebermann M, Trauner M, Reisinger EC, Sauer M. Biosensor for hepatocellular injury corresponds to experimental scoring of hepatosplenic schistosomiasis in mice. BioMed research international. (2016), Art. 1567254, 7 S. dx.doi.org/10.1155/2016/1567254
  • Sponholz C, Matthes K, Rupp D, Backaus W, Klammt S, Karailieva D, Bauschke A, Settmacher U, Kohl M, Clemens MG, Mitzner S, Bauer M, Kortgen A. Molecular adsorbent recirculating system and single-pass albumin dialysis in liver failure : A prospective, randomised crossover study. Critical care. 20(2016), Art. 2. dx.doi.org/10.1186/s13054-015-1159-3
  • Su X, Tárnok A. Cytometry advancement: A perspective from China. Cytometry A. 2016, 89 (12), S. 1049-1051. dx.doi.org/10.1002/cyto.a.23036
  • Tárnok A. Class struggle under the microscope. Cytometry A. 2016, 89 (10), S. 879-880. dx.doi.org/10.1002/cyto.a.23002
  • Tárnok A. Set Them Free! Cytometry A. 2016, 89 (11), S. 965-966. dx.doi.org/10.1002/cyto.a.23020
  • Thoring L, Wüstenhagen DA, Borowiak M, Stech M, Sonnabend A, Kubick S. Cell-Free Systems Based on CHO Cell Lysates: Optimization Strategies, Synthesis of »Difficult-to-Express« Proteins and Future Perspectives. PLoS One. 2016 Sep 29;11(9):e0163670. DOI dx.doi.org/10.1371/journal.pone.0163670 Artikel
  • Tuncel J, Haag S, Hoffmann MH, Yau AC, Hultqvist M, Olofsson P, Bäcklund J, Nandakumar KS, Weidner D, Fischer A, Leichsenring A, Lange F, Haase C, Lu S, Gulko PS, Steiner G, Holmdahl R. Animal models of rheumatoid arthritis (I): Pristane-induced arthritis in the rat. PLoS One. 11 (2016), 5, Art. e0155936, 17 S. dx.doi.org/10.1371/journal.pone.0155936
  • Uhlig K, Wegener T, He J, Zeiser M, Bookhold J, Dewald I, Godino N, Jaeger M, Hellweg T, Fery A, Duschl C. Patterned thermoresponsive microgel coatings for noninvasive processing of adherent cells. Biomacromolecules. 17 (2016), 3, S. 1110-1116. dx.doi.org/10.1021/acs.biomac.5b01728
  • Velandia-Huerto CA, Berkemer SJ, Hoffmann A, Retzlaff N, Romero Marroquín LC, Hernández-Rosales M, Stadler PF, Bermúdez-Santana CI. Orthologs, turn-over, and remolding of tRNAs in primates and fruit flies. BMC Genomics. (2016), 17:617. dx.doi.org/10.1186/s12864-016-2927-4
  • Velandia-Huerto CA, Gittenberger AA, Brown FD, Stadler PF, Bermúdez-Santana CI. Automated detection of ncRNAs in the draft genome sequence of a colonial tunicate: the carpet sea squirt Didemnum vexillum. BMC Genomics. (2016), 17:691. dx.doi.org/10.1186/s12864-016-2934-5
  • Velk N, Uhlig K, Vikulina A, Duschl C, Volodkin D. Mobility of lysozyme in poly(l-lysine)/hyaluronic acid multilayer films. Colloids and surfaces B. 147 (2016), S. 343-350. dx.doi.org/10.1016/j.colsurfb.2016.07.055
  • Vikulina AS, Anissimov YG, Singh P, Prokopović VZ, Uhlig K, Jaeger MS, von Klitzing R, Duschl C, Volodkin D. Temperature effect on the build-up of exponentially growing polyelectrolyte multilayers. An exponential-to-linear transition point. Physical chemistry, chemical physics : PCCP. 18 (2016), 11, S. 7866-7874. dx.doi.org/10.1039/c6cp00345a
  • Wagner L, Björkqvist M, Lundh SH, Wolf R, Börgel A, Schlenzig D, Ludwig HH, Rahfeld JU, Leavitt B, Demuth HU, Petersén Å, von Hörsten S. Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington‘s Disease: increased NPY levels and differential degradation of the NPY1-30 fragment. Journal of neurochemistry. 137 (2016), 5, S. 820-837. dx.doi.org/10.1111/jnc.13624
  • Wege AK, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, Lehmann J. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. mAbs. 6 (2016), 4, S. 968-977. dx.doi.org/10.4161/mabs.29111
  • Wilcke A, Müller B, Schaadt G, Friederici A, Emmrich F, Brauer J, Neef N, Skeide MA,  Kraft I, Czepezauer I, Bobovnikov N, Kirsten H, Boltze J. High acceptance of an early dyslexia screening test involving genetic analyses in Germany. European journal of human genetics. 24 (2016), 2, S. 178-182. dx.doi.org/10.1038/ejhg.2015.103
  • Wittke S, Baxmann S, Fahlenkamp D, Schmiedeknecht G, Kebbel K, Kießig ST. Rationales for a multi-epitope approach in an autologous renal cell cancer immunostimulant. Journal of vaccines & vaccination 7 (2016), 4, Art. 327, 5 S. dx.doi.org/10.4172/2157-7560.1000327
  • Wulff M, Baumann M, Thümmler A, Yadav JK, Heinrich L, Knüpfer U, Schlenzig D, Schierhorn A, Rahfeld JU, Horn U, Balbach J, Demuth HU, Fändrich M. Enhanced fibril fragmenta­tion of n-terminally truncated and pyroglutamyl-modified Aβ peptides. Angewandte Chemie. International edition. 55 (2016), 16, S. 5081-5084. dx.doi.org/10.1002/anie.201511099
  • Zaitseva E, Rio Martinez J del, Dondapati SK, Baaken G, Petersen S, Kubick S, Behrends JC. hERG ion channel activity measured in planar lipid bilayer arrays: Reconstitu­tion from eukaryotic cell-free expression system and cellular membrane preparations. Biophysical journal. 110 (2016), 3, Supplement 1, S. 446a. dx.doi.org/10.1016/j.bpj.2015.11.2399

Publications 2015

  • Barzon L, Pacenti M, Ulbert S, Palù G. Latest developments and challenges in the diagnosis of human West Nile virus infection. Expert review of anti-infective therapy. 13 (2015), 3, S. 327-42. DOI: dx.doi.org/10.1586/14787210.2015.1007044
  • Barzon L, Papa A, Lavezzo E, Franchin E, Pacenti M, Sinigaglia A, Masi G, Trevisan M, Squarzon L, Toppo S, Papadopoulou E, Nowotny N, Ulbert S, Piralla A, Rovida F, Baldanti F, Percivalle E, Palù G. Phylogenetic characterization of Central/Southern European lineage 2 West Nile virus: analysis of human outbreaks in Italy and Greece, 2013-2014. Clinical microbio­logy and infection. 21 (2015), 12, 1122.e1-1122.e10. DOI dx.doi.org/10.1016/j.cmi.2015.07.018
  • Bechlars S, Jäckel C, Diescher S, Wüstenhagen DA, Kubick S, Dieckmann R, Strauch E. Characterization of trh2 Harbouring Vibrio parahaemolyticus Strains Isolated in Germany. PLOS ONE | DOI: dx.doi.org/10.1371/journal.pone.0118559. Article
  • Betat H, Mede T, Tretbar S, Steiner L, Stadler PF, Mörl M, Prohaska SJ. The ancestor of modern Holozoa acquired the CCA-adding enzyme from Alphaproteobacteria by horizontal gene transfer. Nucleic acids research. 43 (2015), 14, 6739-46. DOI: dx.doi.org/10.1093/nar/gkv631
  • Boltze J, Arnold A, Walczak P, Jolkkonen J, Cui L, Wagner DC. The dark side of the force - constraints and complications of cell therapies for stroke. Frontiers in neurology. 6 (2015), 155. DOI dx.doi.org/10.3389/fneur.2015.00155
  • Bosserdt M, Erdőssy J, Lautner G, Witt J, Köhler K, Gajovic-Eichelmann N, Yarman A, Wittstock G, Scheller FW, Gyurcsányi RE. Microelectrospotting as a new method for electrosynthesis of surface-imprinted polymer microarrays for protein recognition. Biosensors and bioelectronics. 73 (2015), S.123-9. DOI dx.doi.org/10.1016/j.bios.2015.05.049
  • Brener O, Dunkelmann T, Gremer L, Van Groent T, Mirecka E, Kadishi I, Willuweit A, Kutzsche J, Jürgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J,  Oesterhelft F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D. QIAD assay for quantitating a compound‘s efficacy in elimination of toxic Aβ oligomers. Scientific Reports. 5 (2015), 13222. DOI dx.doi.org/10.1038/srep13222
  • Brödel AK, Wüstenhagen DA, Kubick S. Cell-Free Protein Synthesis Systems Derived from Cultured Mammalian Cells. Methods Mol Biol. 2015;1261:129-40. doi: dx.doi.org/10.1007/978-1-4939-2230-7_7
  • Buga AM, Scheibe J, Moller K, Ciobanu O, Posel C, Boltze J, Popa-Wagner A. Granulocyte colony-stimulating factor and bone marrow mononuclear cells for stroke treatment in the aged brain. Current neurovascular research. 12 (2015), 2, S. 155-62. DOI dx.doi.org/10.2174/1567202612666150311112550
  • Burkhardt R, Kirsten H, Beutner F, Holdt LM, Gross A, Teren A, Tönjes A, Becker S, Krohn K, Kovacs P, Stumvoll M, Teupser D, Thiery J, Ceglarek U, Scholz M. Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarni­tines in Whole Blood. PLoS Genetics. 11 (2015), 9:e1005510. DOI dx.doi.org/10.1371/journal.pgen.1005510
  • Couturier J-P, Sütterlin M, Laschewsky A, Hettrich C, Wischerhoff E. Inverse Opale aus responsiven Hydrogelen für die Detektion von Makromolekülen. Angew. Chem. 127 (2015) 6741-6745, DOI dx.doi.org/10.1002/ange.201500674
  • Couturier J-P, Sütterlin M, Laschewsky A, Hettrich C, Wischerhoff E. Responsive Inverse Opal Hydrogels for the Sensing of Macromolecules. Angew. Chem. Int. Ed. 54 (2015) 6641-6644, DOI dx.doi.org/10.1002/anie.201500674
  • Cui LL, Kerkelä E, Bakreen A, Nitzsche F, Andrzejewska A, Nowakowski A, Janowski M, Walczak P, Boltze J, Lukomska B, Jolkkonen J. The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity. Stem cell research and therapy. 6 (2015), 11. DOI dx.doi.org/10.1186/scrt544
  • Dammers C, Gremer L, Neudecker P, Demuth HU, Schwarten M, Willbold D. Purification and characteri­zation of recombinant N-Terminally Pyroglutamate-modified Amyloid-β variants and structural analysis by solution NMR spectroscopy. PLoS One. 10 (2015), 10, e0139710. DOI: dx.doi.org/10.1371/journal.pone.0139710
  • Dammers C, Gremer L, Reiß K, Klein AN, Neudecker P, Hartmann R, Sun N, Demuth HU,  Schwarten M, Willbold D. Structural analysis and aggregation propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol. PLoS One. 10 (2015), 11, e0143647. DOI dx.doi.org/10.1371/journal.pone.0143647
  • Ehler J, Koball S, Sauer M, Mitzner S, Hickstein H, Benecke R, Zettl UK. Response to Therapeutic Plasma Exchange as a Rescue Treatment in Clinically Isolated Syndromes and Acute Worsening of Multiple Sclerosis: A Retrospective Analysis of 90 Patients. Plos One 2015 Aug 5;10(8):e0134583. DOI dx.doi.org/10.1371/journal.pone.0134583. eCollection 2015
  • Eisold U, Sellrie F, Schenk JA, Lenz C, Stöcklein WFM, Kumke MU. Bright or dark immune complexes of anti-TAMRA antibodies for tailored fluorescence-based bioanalysis. Analytical and bioanalytical chemistry. 407 (2015), 12, S. 3313-23. DOI dx.doi.org/10.1007/s00216-015-8538-0
  • Engelhardt J, Stadler PF. Evolution of the unspliced transcriptome. BMC Evol Biol. 15 (2015), Aug 20, 166.
  • Fernández AF, Bayón GF, Urdinguio RG, Toraño EG, García MG, Carella A, Petrus-Reurer S, Ferrero C, Martinez-Camblor P, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Bueno C, Menéndez P, Mentink A, Mareschi K, Fabian C, Fagnani C, Medda E, Toccaceli V, Brescianini S, Moran S, Esteller M, Stolzing A, de Boer J, Nisticò L, Stazi MA, Fraga MF. H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells. Genome Research. 2015 Jan;25(1):27-40. DOI dx.doi.org/10.1101/gr.169011.113
  • Feoktistova N, Stoychev G, Puretskiy N, Ionov L, Volodkin D. Porous thermo-responsive pNIPAM microgels. European polymer journal. 68 (2015), S. 65-656. DOI dx.doi.org/10.1016/j.eurpolymj.2015.03.040
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  • Zscharnack M, Krause C, Aust G, Thümmler C, Peinemann F, Keller T, Smink JJ, Holland H, Somerson JS, Knauer J, Schulz RM, Lehmann J. Preclinical good laboratory practice-compliant safety study to evaluate biodistribution and tumorigenicity of a cartilage advanced therapy medicinal product (ATMP). J Transl Med. 2015 May 20;13:160. DOI: dx.doi.org/10.1186/s12967-015-0517-x
  • Zu Siederdissen C, Prohaska SJ, Stadler PF. Algebraic dynamic programming over general data structures. BMC Bioinformatics 16 (2015) Suppl 19, S2. DOI dx.doi.org/10.1186/1471-2105-16-S19-S2

Publications 2014

  • Arnold C, Externbrink F, Hackermüller J, Reiche K. CEMDesigner: Design of custom expression microarrays in the post-ENCODE Era. Journal of Biotechnology. 2014 Nov 10;189:154-6. DOI dx.doi.org/10.1016/j.jbiotec.2014.09.012.
  • Backofen R, Amman F, Costa F, Findeiß S, Richter AS, Stadler PF. Bioinformatics of prokaryotic RNAs. RNA Biology. 2014 May;11(5):470-83. DOI dx.doi.org/10.4161/rna.28647
  • Balseanu AT, Buga AM, Catalin B, Wagner DC, Boltze J, Zagrean AM, Reymann K, Schaebitz W, Popa-Wagner A. Multimodal approaches for regenerative stroke therapies: combination of granulocyte colony-stimulating factor with bone marrow mesenchymal stem cells is not superior to G-CSF alone. Frontiers in Aging Neuroscience. 2014 Jun 23;6:130.DOI dx.doi.org/10.3389/fnagi.2014.00130.
  • Barzon L, Pacenti M, Franchin E, Squarzon L, Sinigaglia A, Ulbert S, Cusinato R, Palù G. Isolation of West Nile virus from urine samples of patients with acute infection. Journal of Clinical Microbiology. 214 Sep;52(9):3411-3. DOI dx.doi.org/10.1128/JCM.01328-14.
  • Boldt A, Borte S, Fricke S, Kentouche K, Emmrich F, Borte M, Kahlenberg F, Sack U. Eight-color immunophenotyping of T-, B-, and NK-cell subpopulations for characterization of chronic immunodeficiencies. Cytometry B Clinical Cytometry. 2014 May;86(3):191-206.DOI: dx.doi.org/10.1002/cyto.b.21162.
  • Boldt A, Kahlenberg F, Fricke S, Rasche FM, Sack U. Flow cytometric phenotyping of lymphocytes in patients with systemic lupus erythematosus. Cytometry A. 2014 Jul;85(7):567-9.DOI: dx.doi.org/10.1002/cyto.a.22477
  • Boldt A, Kentouche K, Fricke S, Borte S, Kahlenberg F, Sack U. Differences in FOXP3 and CD127 expression in Treg-like cells in patients with IPEX syndrome. Clinical Immunoloy. 2014 Jul;153(1):109-11. DOI: dx.doi.org/10.1016/j.clim.2014.04.001
  • Boltze J, Ayata C, Wagner DC, Plesnila N. Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines. Stroke. 2014 Feb;45(2):357. DOI dx.doi.org/10.1161/STROKEAHA.113.004148
  • Boltze J, Lukomska B, Jolkkonen J; MEMS–IRBI consortium. Mesenchymal stromal cells in stroke: improvement of motor recovery or functional compensation? Journal of Cerebral Blood Flow and Metabolism. 2014 Aug;34(8):1420-1. DOI dx.doi.org/10.1038/jcbfm.2014.94
  • Burkhardt J, Blume M, Petit-Teixeira E, Hugo Teixeira V, Steiner A, Quente E, Wolfram G, Scholz M, Pierlot C, Migliorini P, Bombardieri S, Balsa A, Westhovens R, Barrera P, Radstake TR, Alves H, Bardin T, Prum B, Emmrich F, Cornelis F, Ahnert P, Kirsten H. Cellular adhesion gene SELP is associated with rheumatoid arthritis and displays differential allelic expression. PLoS One. 2014 Aug 22;9(8):e103872. DOI dx.doi.org/10.1371/journal.pone.0103872
  • Chabierski S, Barzon L, Papa A, Niedrig M, Bramson JL, Richner JM, Palù G, Diamond MS, Ulbert S. Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop. BMC Infectious Diseases. 2014 May 9;14:246. DOI dx.doi.org/10.1186/1471-2334-14-246
  • Cynis H, Funkelstein L, Toneff T, Mosier C, Ziegler M, Koch B, Demuth HU, Hook V. Pyroglutamate-Amyloid-? and Glutaminyl Cyclase Are Colocalized with Amyloid-? in Secretory Vesicles and Undergo Activity-Dependent, Regulated Secretion. Neurodegenerative Diseases. 2014; 14(2):85-97. DOI dx.doi.org/10.1159/000358430
  • Danckert L, Hoppe S, Bier FF, von Nickisch-Rosenegk M. Rapid identification of novel antigens of Salmonella Enteritidis by microarray-based immunoscreening. Microchimica Acta 02/2014; • 3.43 Impact Factor.
  • Danielyan L, Beer-Hammer S, Stolzing A, Schäfer R, Siegel G, Fabian C, Kahle P, Biedermann T, Lourhmati A, Buadze M, Novakovic A, Proksch B, Gleiter CH, Frey WH, Schwab M. Intranasal delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer‘s and Parkinson‘s disease. Cell Transplantation. 2014;23 Suppl 1:123-39. DOI dx.doi.org/10.3727/096368914X684970
  • Dechtrirat D, Gajovic-Eichelmann N, Bier FF, Scheller FW. Hybrid Material for Protein Sensing Based on Electrosynthesized MIP on a Mannose Terminated Self-Assembled Monolayer. Adv Func Mater, 24 (2014): 2233-2239.
  • Dechtrirat D, Gajovic-Eichelmann N, Wojcik F, Hartmann L, Bier FF, Scheller FW. Electrochemical displacement sensor based on ferrocene boronic acid tracer and immobilized glycan for saccharide binding proteins and E. Coli. Biosens Bioelectron. 58 (2014): 1-8.
  • De Filette M, Chabierski S, Andries O, Ulbert S, Sanders NN. T cell epitope mapping of the e-protein of west nile virus in BALB/c mice. PLoS One. 2014 Dec 15;9(12):e115343.DOI: dx.doi.org/10.1371/journal.pone.0115343
  • De Filette M, Soehle S, Ulbert S, Richner J, Diamond MS, Sinigaglia A, Barzon L, Roels S, Lisziewicz J, Lorincz O, Sanders NN. Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge. PLoS One. 2014 Feb 4;9(2):e87837. DOI dx.doi.org/10.1371/journal.pone.0087837
  • de Vera J-P, Boettger U, Lorek A, Wolter D, Grunow D, Hübers H-W, Spohn T, Noetzel RdlT, Sánchez FJ, Billi D, Baqué M, Rettberg P, Rabbow E, Reitz G, Berger T, Leuko S, Möller R, Bohmeier M, Horneck G, Westall F, Jänchen J, Fritz J, Meyer C, Onofri S, Selbmann L, Zucconi L, Kozyrovska N, Leya T, Foing B, Demets R, Cockell CS, Bryce C, Philips Brown S, Olsson-Francis K, Wagner D, Serrano P, Edwards HGM, Joshi J, Huwe B, Moritz S, Ehrenfreund P, Elsaesser A, Ott S, Meessen J, Feyh N, Szewzyk U, Schulze-Makuch D, Hermelink A, Lasch P. BIOMEX – the Biology and Mars Experiment in space during the EXPOSE-R2 mission on the ISS. GRA. 2014;16.
  • Diederich K, Schmidt A, Beuker C, Strecker JK, Wagner DC, Boltze J, Schäbitz WR, Minnerup J. Granulocyte colony-stimulating factor (G-CSF) treatment in combination with transplantation of bone marrow cells is not superior to G-CSF treatment alone after cortical stroke in spontaneously hypertensive rats. Frontiers in Cellular Neuroscience. 2014 Dec 4;8:411. DOI dx.doi.org/10.3389/fncel.2014.00411
  • Dondapati SK, Kreir M, Quast RB, Wüstenhagen DA, Brüggemann A, Fertig N, Kubick S. Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system. Biosens Bioelectron. 2014 Sep 15;59:174-83.
  • Ehler J, Koball S, Sauer M, Hickstein H, Mitzner S, Benecke R, Zettl UK. Therapeutic plasma exchange in glucocorticosteroid-unresponsive patients with Clinically Isolated Syndrome. Therapeutic Apheresis and Dialysis. 2014 Oct;18(5):489-96.DOI dx.doi.org/10.1111/1744-9987.12176
  • Ermilova E, Bier FF, Hölzel R. Dielectric measurements of aqueous DNA solutions up to 110 GHz. Phys. Chem. Chem. Phys., 16 (2014): 11256-11264.
  • Faissner S, Ambrosius B, Schanzmann K, Grewe B, Potthoff A, Münch J, Sure U, Gramberg T, Wittmann S, Brockmeyer N, Uberla K, Gold R, Grunwald T, Chan A. Cytoplasmic HIV-RNA in monocytes determines microglial activation and neuronal cell death in HIV-associated neurodegeneration. Experimental Neurology. 2014 Nov;261:685-97. DOI dx.doi.org/10.1016/j.expneurol.2014.08.011
  • Fenz SF, Sachse R, Schmidt T, Kubick S. Cell-free synthesis of membrane proteins: tailored cell models out of microsomes. Biochimica et Biophysica Acta. 2014 May;1838(5):1382-8. DOI dx.doi.org/10.1016/j.bbamem.2013.12.009
  • Flemmig J, Schwarz P, Bäcker I, Leichsenring A, Lange F, Arnhold J. Rapid and reliable determination of the halogenating peroxidase activity in blood samples. Journal of Immunological Methods. 2014 Dec 15;415:46-56. DOI dx.doi.org/10.1016/j.jim.2014.09.003
  • Fricke S, Hilger N, Fricke C, Schönfelder U, Behre G, Ruschpler P, Boldt A, Oelkrug C, Sack U, Emmrich F. Prevention of graft-versus-host-disease with preserved graft-versus-leukemia-effect by ex vivo and in vivo modulation of CD4(+) T-cells. Cellular and Molecular Life Science. 2014 Jun;71(11):2135-48.DOI: dx.doi.org/10.1007/s00018-013-1476-0
  • Fricke S, Pfefferkorn C, Wolf D, Riemschneider S, Kohlschmidt J, Hilger N, Fueldner C, Knauer J, Sack U, Emmrich F, Lehmann J. Characterization of the murine myeloid precursor cell line MuMac-E8. PLoS One. 2014 Dec 29;9(12):e113743. DOI: dx.doi.org/10.1371/journal.pone.0113743
  • Friedrich S, Schmidt T, Geissler R, Lilie H, Chabierski S, Ulbert S, Liebert UG, Golbik RP, Behrens SE. AUF1 p45 promotes West Nile virus replication by an RNA chaperone activity that supports cyclization of the viral genome. Journal of Virology. 2014 Oct;88(19):11586-99.DOI: dx.doi.org/10.1128/JVI.01283-14
  • Frimmel S, Schipper J, Henschel J, Yu TT, Mitzner SR, Koball S. First description of single-pass albumin dialysis combined with cytokine adsorption in fulminant liver failure and hemophagocytic syndrome resulting from generalized herpes simplex virus 1 infection. Liver Transplantation. 2014 Dec;20(12):1523-4. DOI dx.doi.org/10.1002/lt.24005
  • Fronz U, Deten A, Baumann F, Kranz A, Weidlich S, Härtig W, Nieber K, Boltze J, Wagner DC. Continuous adenosine A2A receptor antagonism after focal cerebral ischemia in spontaneously hypertensive rats. Naunyn Schmiedeberg's Archives of Pharmacoloy. 2014 Feb;387(2):165-73. DOI dx.doi.org/10.1007/s00210-013-0931-7
  • Füllbrandt M, Ermilova E, Asadujjaman A, Hölzel R, Bier FF, von Klitzing R, Schönhals A. Dynamics of Linear Poly(N-isopropylacrylamide) in Water around the Phase Transition Investigated by Dielectric Relaxation Spectroscopy. J Phys Chem B. 118 (2014): 3750-3759.
  • Grunwald T, Tenbusch M, Schulte R, Raue K, Wolf H, Hannaman D, de Swart RL, Uberla K, Stahl-Hennig C. Novel vaccine regimen elicits strong airway immune responses and control of respiratory syncytial virus in nonhuman primates. Journal of Virology. 2014 Apr;88(8):3997-4007. DOI dx.doi.org/10.1128/JVI.02736-13
  • Haag M, Augst H, Kebbel K, Ringe J, Van Linthout S, Thielemann D, Kellert C, Schmiedeknecht G, Tschoepe C, Sittinger M. Human cardiac derived cells for the treatment of chronic heart failure - from bench to bedside. Kooperationsforum - Technologien für zellbasierte Therapien, Erlangen 2014, Tagungsband S. 118-19.
  • Hacht AV, Seifert O, Menger M, Schütze T, Arora A, Konthur Z, Neubauer P, Wagner A, Weise C, Kurreck J. Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic Acids Res. (2014), 42 (10): 6630-6644; doi: 10.1093/nar/gku290. PMID: 24771345.
  • Hackermüller J, Reiche K, Otto C, Hösler N, Blumert C, Brocke-Heidrich K, Böhlig L, Nitsche A, Kasack K, Ahnert P, Krupp W, Engeland K, Stadler PF, Horn F. Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs. Genome Biology. 2014 Mar 4;15(3):R48. DOI dx.doi.org/10.1186/gb-2014-15-3-r48
  • Hass J, Walton E, Kirsten H, Turner J, Wolthusen R, Roessner V, Sponheim SR, Holt D, Gollub R, Calhoun VD, Ehrlich S. Complexin2 modulates working memory-related neural activity in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 2014 Oct 9. [Epub ahead of print] DOI dx.doi.org/10.1007/s00406-014-0550-4
  • Herbel S, von Nickisch-Rosenegk M, Kuhn M, Murugaiyan J, Wieler LH, Guenther S. Specific TaqMan Probes for the Identification and Quantification of Lactobacilli in Pharmaceuticals. Journal of Probiotics & Health. 02/2014; 2(1).
  • Hoffmann A, Stoffel MH, Nitzsche B, Lobsien D, Seeger J, Schneider H, Boltze J. The ovine cerebral venous system: comparative anatomy, visualization, and implications for translational research. PLoS One. 2014 Apr 15;9(4):e92990. DOI dx.doi.org/10.1371/journal.pone.0092990
  • Hoffmann S, Otto C, Doose G, Tanzer A, Langenberger D, Christ S, Kunz M, Holdt LM, Teupser D, Hackermüller J, Stadler PF. A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection. Genome Biology. 2014 Feb 10;15(2):R34. DOI dx.doi.org/10.1186/gb-2014-15-2-r34
  • Höfling C, Indrischek H, Höpcke T, Waniek A, Cynis H, Koch B, Schilling S, Morawski M, Demuth HU, Roßner S, Hartlage-Rübsamen M. Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC. International Journal of Developmental Neuroscience. 2014 Aug; 36:64-73. DOI dx.doi.org/10.1016/j.ijdevneu.2014.05.008
  • Hoppe S, Bier FF, von Nickisch-Rosenegk M. Identification of antigenic proteins of the nosocomial pathogen Klebsiella pneumoniae. PLoS One 9(10): e110703. Doi dx.doi.org/10.1371/journal.pone.0110703
  • Hovestädt M, Memczak H, Pleiner D, Zhang X, Rappich J, Bier FF, Stöcklein WFM. Characterization of a new maleimido functionalization of gold for surface plasmon resonance spectroscopy. J. Mol. Recognit. 2014, in press, DOI: 10.1002/jmr.2396.
  • Hüttl C, Hettrich C, Riedel M, Henklein P, Rawel H, Bier FF. Development of peptidyl lysine dendrons: 1,3-Dipolar cycloaddition for peptide coupling and antibody recognition. Chemical Biology and Drug Design. 2014 Oct 7. DOI dx.doi.org/10.1111/cbdd.12444
  • Kaiser D, Weise G, Möller K, Scheibe J, Pösel C, Baasch S, Gawlitza M, Lobsien D, Diederich K, Minnerup J, Kranz A, Boltze J, Wagner DC. Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease. Acta Neuropatholica Communications. 2014 Dec 18;2(1):169. DOI dx.doi.org/10.1186/s40478-014-0169-8
  • Kersting S, Rausch V, Bier FF, von Nickisch-Rosenegk M. Rapid detection of Plasmodium falciparum with isothermal recombinase polymerase amplification and lateral flow analysis. Malaria J., 13 (2014):99. (e1-e9).
  • Kersting S, Rausch V, Bier FF, von Nickisch-Rosenegk M. Multiplex isothermal solid-phase recombinase polymerase amplification for the specific and fast DNA-based detection of three bacterial pathogens. Mikrochim Acta. 181 (2014):1715-1723.
  • Klammt S, Mitzner SR, Reisinger EC, Stange J. No sustained impact of intermittent extracorporeal liver support on thrombocyte time course in a randomized controlled albumin dialysis trial. Therapeutic Apheresis and Dialysis. 2014 Oct;18(5):502-8. DOI dx.doi.org/10.1111/1744-9987.12124
  • Korenic A, Boltze J, Deten A, Peters M, Andjus P, Radenovi? L. Astrocytic Mitochondrial Membrane Hyperpolarization following Extended Oxygen and Glucose Deprivation. PLoS One. 2014 Feb 28;9(2):e90697. doi: 10.1371/journal.pone.0090697.
  • Kozma P, Kehl F, Ehrentreich-Förster E, Stamm C, Bier FF. Integrated planar optical waveguide interferometer biosensors: A comparative review. Biosens. Bioelectron. 58 (2014):287-307.
  • Kucharík M, Hofacker IL, Stadler PF, Qin J. Basin hopping graph: a computational framework to characterize RNA folding landscapes. Bioinformatics. 2014 Jul 15;30(14):2009-17. DOI dx.doi.org/10.1093/bioinformatics/btu156
  • Kumke M, Eisold U, Sellrie F, Schenk J, Stöcklein W, Lenz C. Bright or dark immune complexes of anti-TAMRA antibodies for tailored fluorescence based bioanalysis. Anal. Bioanal. Chem. 2014 eingereicht.
  • Laux EM, Kaletta UC, Bier FF, Wenger C, Hölzel R. Functionality of dielectrophoretically immobilized enzyme molecules. Electrophoresis. 35 (2014): 459-466.
  • Lechner M, Hernandez-Rosales M, Doerr D, Wieseke N, Thévenin A, Stoye J, Hartmann RK, Prohaska SJ, Stadler PF. Orthology detection combining clustering and synteny for very large datasets. PLoS One. 2014 Aug 19;9(8):e105015. DOI dx.doi.org/10.1371/journal.pone.0105015
  • Lehmann J, Härtig W, Seidel A, Füldner C, Hobohm C, Grosche J, Krueger M, Michalski D. Inflammatory cell recruitment after experimental thromboembolic stroke in rats. Neuroscience. 2014 Oct 24; 279:139-154. DOI: dx.doi.org/10.1016/j.neuroscience.2014.08.023
  • Lehmann J, Härtig W, Seidel A, Füldner C, Fuhs T, Hobohm C, Grosche J, Krüger M, Michalski D. Reevaluating the local inflammatory response in stroke – a translational-inspired study using the human-like thromboembolic model in rats. Neuroscience (2014) Aug 26. pii: S0306-4522(14)00699-X. doi: 10.1016/j.neuroscience.2014.08.023. [Epub ahead of print].
  • Magnusson SE, Karlsson KH, Reimer JM, Corbach-Söhle S, Patel S, Richner JM, Nowotny N, Barzon L, Bengtsson KL, Ulbert S, Diamond MS, Stertman L. Matrix-M™ adjuvanted envelope protein vaccine protects against lethal lineage 1 and 2 West Nile virus infection in mice. Vaccine. 2014 Feb 7;32(7):800-8. DOI dx.doi.org/10.1016/j.vaccine.2013.12.030
  • Mann M, Nahar F, Schnorr N, Backofen R, Stadler PF, Flamm C. Atom mapping with constraint programming. Algorithms for Molecular Biology. 2014 Nov 29;9(1):23. DOI dx.doi.org/10.1186/s13015-014-0023-3
  • Minnerup J, Wagner DC, Strecker JK, Pösel C, Sevimli-Abdis S, Schmidt A, Schilling M, Boltze J, Diederich K, Schäbitz WR. Bone marrow-derived mononuclear cells do not exert acute neuroprotection after stroke in spontaneously hypertensive rats. Frontiers in Cellular Neuroscience. 2014 Jan 8;7:288. DOI dx.doi.org/10.3389/fncel.2013.00288
  • Möller K, Boltze J, Pösel C, Seeger J, Stahl T, Wagner DC. Sterile inflammation after permanent distal MCA occlusion in hypertensive rats. Journal of Cerebral Blood Flow and Metabolism. 2014 Feb;34(2):307-15. DOI dx.doi.org/10.1038/jcbfm.2013.199
  • Morawski M, Schilling S, Kreuzberger M, Waniek A, Jäger C, Koch B, Cynis H, Kehlen A, Arendt T, Hartlage-Rübsamen M, Demuth HU, Roßner S. Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-beta load and cognitive decline in Alzheimer‘s disease. Journal of Alzheimer‘s Disease. 2014;39(2):385-400. DOI dx.doi.org/10.3233/JAD-131535
  • Mueller B, Ahnert P, Burkhardt J, Brauer J, Czepezauer I, Quente E, Boltze J, Wilcke A, Kirsten H. Genetic risk variants for dyslexia on chromosome 18 in a German cohort. Genes, Brain and Behavior. 2014 Mar;13(3):350-6. DOI dx.doi.org/10.1111/gbb.12118
  • Nickels PC, Ke Y, Jungmann R, Smith DM, Leichsenring M, Shih WM, Liedl T, Högberg B. DNA origami structures directly assembled from intact bacteriophages. Small. 2014 May 14;10(9):1765-9. DOI dx.doi.org/10.1002/smll.201303442
  • Oelkrug C, Lange CM, Wenzel E, Fricke S, Hartke M, Simasi J, Schubert A. Analysis of the tumoricidal and anti-cachectic potential of curcumin. Anticancer Research. 2014 Sep;34(9):4781-8.
  • Oelkrug C, Hilger N, Schönfelder U, Boltze J, Sack U, Fricke C, Hildebrandt G, Keller T, Emmrich F, Fricke S. Modelling hematological parameters after total body irradiation. International Journal of Radiation Biology. 2014 Jul;90(7):538-46. DOI: dx.doi.org/10.3109/09553002.2014.899443
  • Oelkrug C, Ramage JM. Enhancement of T cell recruitment and infiltration into tumours. Clinical and Experimental Immunology. 2014 Oct;178(1):1-8. DOI dx.doi.org/10.1111/cei.12382
  • Otto S, Kaletta U, Bier FF, Wenger C, Hölzel R. Dielectrophoretic immobilisation of antibodies on microelectrode arrays. Lab Chip. 14 (2014): 998-1004.
  • Patra D, Fasold M, Langenberger D, Steger G, Grosse I, Stadler PF. plantDARIO: web based quantitative and qualitative analysis of small RNA-seq data in plants. Frontiers in Plant Science. 2014 Dec 23;5:708. DOI dx.doi.org/10.3389/fpls.2014.00708
  • Paulraj T, Feoktistova N, Velk N, Uhlig K, Duschl C, Volodkin D. Microporous polymeric 3D scaffolds templated by the layer-by-layer self-assembly. Macromolecular rapid communications. 2014 Aug;35(16):1408-13. DOI dx.doi.org/10.1002/marc.201400253
  • Pieroh P, Koch M, Wagner DC, Boltze J, Ehrlich A, Ghadban C, Hobusch C, Birkenmeier G, Dehghani F. Temporal dynamics of glyoxalase 1 in secondary neuronal injury. PLoS One. 2014 Feb 3;9(2):e87364. DOI dx.doi.org/10.1371/journal.pone.0087364
  • Pösel C, Scheibe J, Kranz A, Bothe V, Quente E, Fröhlich W, Lange F, Schäbitz WR, Minnerup J, Boltze J, Wagner DC. Bone marrow cell transplantation time-dependently abolishes efficacy of granulocyte colony-stimulating factor after stroke in hypertensive rats. Stroke. 2014 Aug;45(8):2431-7.DOI dx.doi.org/10.1161/STROKEAHA.113.004460
  • Pösel C, Uri A, Schulz I, Boltze J, Weise G, Wagner DC. Flow cytometric characterization of brain dendritic cell subsets after murine stroke. Experimental and Translational Stroke Medicine. 2014 Nov 4;6(1):11. DOI dx.doi.org/10.1186/2040-7378-6-11
  • Pratsch K, Wellhausen R, Seitz H. Advances in the quantification of protein microarrays. Curr Opin Chem Biol Feb 2014; Vol 18; 16-20.
  • Prill S, Jaeger, MS, Duschl C. Long-term microfluidic glucose and lactate monitoring in hepatic cell culture. Biomicrofluidics. (2014) 8, 034102.
  • Qin J, Fricke M, Marz M, Stadler PF, Backofen R. Graph-distance distribution of the Boltzmann ensemble of RNA secondary structures. Algorithms for Molecular Biology. 2014 Sep 11;9:19. DOI dx.doi.org/10.1186
  • Rapsch K, Bier FF, von Nickisch-Rosenegk M. Rational Design of Artificial Beta-Strand-Forming Antimicrobial Peptides with Biocompatible Properties. Mol Pharm. 2014 Oct 6;11(10):3492-502. doi: 10.1021/mp500271c. Epub 2014 Sep 22. PubMed PMID: 25192319.
  • Reiche K, Kasack K, Schreiber S, Lüders T, Due EU, Naume B, Riis M, Kristensen VN, Horn F, Børresen-Dale AL, Hackermüller J, Baumbusch LO. Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes. PLoS One. 2014 Sep 29;9(9):e106076. DOI dx.doi.org/10.1371/journal.pone.0106076
  • Reinhardt A, Horn M, Pieper J gen. Schmauck, Bröhl A, Giernoth R, Oelkrug C, Schubert A, Neundorf I. Novel imidazolium salt-peptide conjugates and their antimicrobial activity. Bioconjugate Chemistry. 2014 Dec 17;25(12):2166-74. DOI dx.doi.org/10.1021/bc500510c
  • Roshyara NR, Kirsten H, Horn K, Ahnert P, Scholz M. Impact of pre-imputation SNP-filtering on genotype imputation results. BMC Genetics. 2014 Aug 12;15:88. DOI dx.doi.org/10.1186/s12863-014-0088-5
  • Sachse R, Dondapati SK, Fenz SF, Schmidt T, Kubick S. Membrane protein synthesis in cell-free systems: from bio-mimetic systems to bio-membranes. FEBS Letter. 2014 Aug 25;588(17):2774-81. DOI dx.doi.org/10.1016/j.febslet.2014.06.007
  • Sahyoun AH, Bernt M, Stadler PF, Tout K. GC skew and mitochondrial origins of replication. Mitochondrion. 2014 Jul;17:56-66. DOI dx.doi.org/10.1016/j.mito.2014.05.009
  • Sandetskaya N, Naumann A, Hennig K, Kuhlmeier D. Specific enrichment of prokaryotic DNA using a recombinant DNA-binding protein. Analytical and Bioanalytical Chemistry. 2014 Jun;406(15):3755-62. DOI dx.doi.org/10.1007/s00216-014-7787-7.
  • Scheller FW, Yarman A, Bachmann T, Hirsch T, Kubick S, Renneberg R, Schumacher S, Wollenberger U, Teller C, Bier FF. Future of Biosensors: A Personal View. Adv Biochem Eng Biotechnol. 140 (2014):1-28.
  • Schmidt S, Uhlig K, Duschl C, Volodkin DV. Stability and Cell Uptake of Calcium Carbonate Templated Insulin Microparticles. Acta Biomaterialia (2014), 10, S. 1423-1430.
  • Schmiedeknecht G. Besondere Herausforderungen bei der Herstellung von ATMP. »The Product is the Process – Is it?« Qualitätsaspekte bei der Herstellung von ATMP, November 4, 2014, Berlin.
  • Schmiedeknecht G. Translational research initiatives in Germany: Experiences on cell processing services. Clinical Evaluation, Vol. 42, No. 1, Jul. 2014, page 87-94.
  • Schmiedeknecht G, Kebbel K, Sonnabend C, Wagner M, Gryczka M, Stella M, Ganjei K, Bosch M, Powers LF. Process transfer of DCVax®-L to Europe and initiation of a phase III clinical trial in UK and Germany. ISCT (International Society for Cell Therapy) 2014 Annual Meeting, Paris, France, April 23–26, 2014.
  • Schmiedeknecht G, Kebbel K. Challenges of Manufacturing of ATMP’s for clinical trials. PACT (Platform for Advanced Cellular Therapies Austria) Foundation Symposium, Vienna, Austria, April 3–4, 2014.
  • Schmiedeknecht G. Translational Research Initiatives in Germany: Experiences on Cell Processing Services. Translational Research Center Workshop, organized by the Foundation for Biomedical Research and Innovation (FBRI) and Ministry of Education, Culture, Sports, Science and Technology (MEXT), Tokyo, Japan, February 27, 2014.
  • Schreml S, Meier RJ, Kirschbaum M et al.Luminescent Dual Sensors Reveal Extracellular pH-Gradients and Hypoxia on Chronic Wounds That Disrupt Epidermal Repair Theranostics. (2014), 4, S. 721-735.
  • Schulz I, Engel C, Niestroj AJ, Kehlen A, Rahfeld JU, Kleinschmidt M, Lehmann K, Roßner S, Demuth HU. A non-canonical function of eukaryotic elongation factor 1A1: regulation of interleukin-6 expression. Biochimica et Biophysica Acta – Molecular Cell Research. 2014 May;1843(5):965-75. DOI dx.doi.org/10.1016/j.bbamcr.2014.01.022
  • Schwertassek U, Haque A, Krishnan N, Greiner R, Weingarten L, Dick TP, Tonks NK. Reactivation of oxidized PTP1B and PTEN by thioredoxin 1. FEBS Journal. 2014 Aug;281(16):3545-58. DOI: dx.doi.org/10.1111/febs.12898
  • Sharma A, Wendland R, Sung B, Wu W, Grunwald T, Worgall S. Maternal immunization with chimpanzee adenovirus expressing RSV fusion protein protects against neonatal RSV pulmonary infection. Vaccine. 2014 Sep 29;32(43):5761-8. DOI dx.doi.org/10.1016/j.vaccine.2014.08.049
  • Simasi J, Oelkrug C, Schubert A, Nieber K, Gillissen A. The role of BIM-EL and BCL2-? on the efficacy of erlotinib and gefitinib in lung cancer. Respiratory Physiology and Neurobioly. 2014 Oct 6. pii: S1569-9048(14):259-6.DOI: dx.doi.org/10.1016/j.resp.2014.09.022
  • Simasi J, Schubert A, Oelkrug C, Gillissen A, Nieber K. Primary and secondary resistance to tyrosine kinase inhibitors in lung cancer. Anticancer Res. 2014 Jun;34(6):2841-50.
  • Stech M, Hust M, Schulze C, Dübel S, Kubick S. Cell-free eukaryotic systems for the production, engineering, and modification of scFv antibody fragments. Engineering in Life Sciences. 20104;14(4):387–398. DOI dx.doi.org/10.1002/elsc.201400036
  • Stech M, Quast RB, Sachse R, Schulze C, Wüstenhagen DA, Kubick S. A continuous-exchange cell-free protein synthesis system based on extracts from cultured insect cells. PLoS One 9 (2014) e96635.
  • Tanne J, Dietzel B, Scheller FW, Bier F. Nanohybrid Materials Consisting of Poly[(3-aminobenzoic acid)-co-(3-aminobenzenesulfonic acid)-co-aniline] and Multiwalled Carbon Nanotubes for Immobilization of Redox Active Cytochrome c. Electroanalysis 26 (2014): 732–738.
  • Tanne J, Kracher D, Dietzel B, Schulz B, Ludwig R, Lisdat F, Scheller FW, Bier FF. Carboxylated or aminated polyaniline-multiwalled carbon nanotubes nanohybrids for immobilization of cellobiose dehydrogenase on gold electrodes. Biosensors. 2014 Oct 22;4(4):370-386. DOI dx.doi.org/10.3390/bios4040370
  • Tönjes A, Scholz M, Breitfeld J, Marzi C, Grallert H, Gross A, Ladenvall C, Schleinitz D, Krause K, Kirsten H, Laurila E, Kriebel J, Thorand B, Rathmann W, Groop L, Prokopenko I, Isomaa B, Fasshauer M, Klöting N, Gieger C, Blüher M, Sturmvoll M, Kovacs P. Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genetics. 2014 Dec 18;10(12):e1004854. DOI dx.doi.org/10.1371/journal.pgen.1004854
  • Ueberham U, Rohn S, Ueberham E, Wodischeck S, Hilbrich I, Holzer M, Brückner MK, Gruschka H, Arendt T. Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease. Neuropathology and Applied Neurobiology. 2014 Dec;40(7):815-32.DOI: dx.doi.org/10.1111/nan.12163
  • Ueberham E, Glockner P, Gohler C, Straub BK, Teupser D, Schonig K, Braeuning A, Hohn AK, Jerchow B, Birchmeier W, Gaunitz F, Arendt T, Sansom O, Gebhardt R, Ueberham U. Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a Negative Tumors. Molecular Cancer Research, 2014 Sep 30. DOI: dx.doi.org/10.1158/1541-7786.MCR-14-0278-T
  • Uhlig K, Boerner HG, Wischerhoff E, Lutz JF, Jaeger MS, Laschewsky A, Duschl C. On the interaction of adherent cells with thermoresponsive polymer coatings. Polymers. (2014), 6, 1164-1177.
  • Ulbert S, Magnusson SE. Technologies for the development of West Nile virus vaccines. Future Microbiology. 2014;9(10):121-32. DOI dx.doi.org/10.2217/fmb.14.67
  • Verstrepen BE, Fagrouch Z, van Heteren M, Buitendijk H, Haaksma T, Beenhakker N, Palù G, Richner JM, Diamond MS, Bogers WM, Barzon L, Chabierski S, Ulbert S, Kondova I, Verschoor EJ. Experimental infection of rhesus macaques and common marmosets with a European strain of West Nile virus. PLoS Neglected Tropical Diseases. 2014 Apr 17;8(4):e2797. DOI dx.doi.org/10.1371/journal.pntd.0002797
  • Verstrepen BE, Oostermeijer H, Fagrouch Z, Van Heteren M, Niphuis H, Haaksma T, Kondova I, Bogers WM, De Filette M, Sanders N, Stertman L, Magnusson S, Lörincz O, Lisziewicz J, Barzon L, Palù G, Diamond MS, Chabierski S, Ulbert S, Verschoor E.J. Vaccine-induced protection of rhesus macaques against plasma viremia after intradermal infection with a European lineage 1 strain of West Nile virus. PLoS One, 9 (2014), e112568. DOI dx.doi.org/10.1371/journal.pone.0112568
  • Vochem R, Einenkel J, Horn LC, Ruschpler P. Die Bedeutung der Tumorstammzellhypothese für das Verständnis des Ovarialkarzinoms. Der Pathologe. 2014 Jul;35(4):361-70. DOI dx.doi.org/10.1007/s00292-014-1910-6
  • von Klitzing R, Volodkin DV. Competing mechanisms in polyelectrolyte multilayer formation and swelling: Polycation–polyanion pairing vs. polyelectrolyte–ion pairing. Curr. Opinion Colloid Interface Sci. (2014), in press.
  • Wagner DC, Pösel C, Schulz I, Schicht G, Boltze J, Lange F, Scheibe J, Möller K, Weise G. Allometric dose retranslation unveiled substantial immunological side effects of granulocyte colony-stimulating factor after stroke. Stroke. 2014 Feb;45(2):623-6. DOI dx.doi.org/10.1161/STROKEAHA.113.003812
  • Wege AK, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, Lehmann J. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. mAbs. 2014 Jul-Aug;6(4):968-77. DOI dx.doi.org/10.4161/mabs.29111
  • Weiler G, Schröder C, Schera F, Dobkowicz M, Kiefer S, Heidtke K R, Hänold S, Nwankwo I, Forgo N, Stanulla M, Eckert C, Graf N. p-BioSPRE – an information and communication technology framework for transnational biomaterial sharing and access. ecancer medical science 2014(8).
  • Weis S, Schlaich TC, Dehghani F, Carvalho T, Sommerer I, Fricke S, Kahlenberg F, Mössner J, Hoffmeister A. p8 Deficiency causes siderosis in spleens and lymphocyte apoptosis in acute pancreatitis. Pancreas. 2014 Nov;43(8):1277-85. DOI: dx.doi.org/10.1097/MPA.0000000000000172
  • Weise G, Lorenz M, Pösel C, Maria Riegelsberger U, Störbeck V, Kamprad M, Kranz A, Wagner DC, Boltze J. Transplantation of cryopreserved human umbilical cord blood mononuclear cells does not induce sustained recovery after experimental stroke in spontaneously hypertensive rats. Journal of Cerebral Blood Flow and Metabolism. 2014 Jan;34(1):e1-9. DOI dx.doi.org/10.1038/jcbfm.2013.185
  • Verstrepen BE, Fagrouch Z, van Heteren M, Buitendijk H, Haaksma T, Beenhakker N, Palù G, Richner JM, Diamond MS, Bogers WM, Barzon L, Chabierski S, Ulbert S, Kondova I, Verschoor EJ. Experimental infection of rhesus macaques and common marmosets with a European strain of west nile virus. PLoS Negl Trop Dis. 2014 Apr 17;8(4):e279.
  • Xu LX, Holland H, Kirsten H, Ahnert P, Krupp W, Bauer M, Schober R, Mueller W, Fritzsch D, Meixensberger J, Koschny R. Three gangliogliomas: Results of GTG-banding, SKY, genome-wide high resolution SNP-array, gene expression and review of the literature. Neuropathology. 2014 Nov 6. DOI dx.doi.org/10.1111/neup.12176
  • Zoldan K, Moellmer T, Schneider J, Fueldner C, Knauer J, Lehmann J. Increase of CD25 expression on bovine neutrophils correlates with disease severity in post-partum and early lactating dairy cows. Developmental and comparative immunology. 2014 Dec; 47(2):254-63. DOI: dx.doi.org/10.1016/j.dci.2014.08.002

Publications 2013

  • Arnold C, Stadler PF, Prohaska SJ. Chromatin computation: Epigenetic inheritance as a pattern reconstruction problem. Journal of theoretical biology 336 (2013), S. 61–74. DOI dx.doi.org/10.1016/j.jtbi.2013.07.012
  • Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, Saliba F, Sauerbruch T, Klammt S, Ockenga J, Pares A, Wendon J, Brünnler T, Kramer L, Mathurin P, de la Mata M, Gasbarrini A, Müllhaupt B, Wilmer A, Laleman W, Eefsen M, Sen S, Zipprich A, Tenorio T, Pavesi M, Schmidt HH, Mitzner S, Williams R, Arroyo V; RELIEF study group. Extracor­poreal albumin dialysis with the molecular adsorbent re­cir­cu­lating system in acute-on-chronic liver failure: the RELIEF trial. Hepatology. 57(2013), 3, S. 1153–62. DOI dx.doi.org/10.1002/hep.26185
  • Becker A, Kohlmann S, Alexan­dru A, Jagla W, Canneva F, Bäuscher C, Cynis H, Sedlmeier R, Graubner S, Schilling S, Demuth HU, von Hörsten S. Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration. BMC Neurosci. 2013 Oct 1;14:108. DOI dx.doi.org/10.1186/1471-2202-14-108
  • Bernt M, Bleidorn C, Braband A, Dambach J, Donath A, Fritzsch G, Golombek A, Hadrys H, Jühling F, Meusemann K, Middendorf M, Misof B, Perseke M, Podsiad­lowski L, Reumont B von, Schierwater B, Schlegel M, Schrödl M, Simon S, Stadler PF, Stöger I, Struck TH. A comprehensive analysis of bilaterian mitochondrial genomes and phylogeny. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 352–364. DOI dx.doi.org/10.1016/j.ympev.2013.05.002
  • Bernt M, Braband A, Middendorf M, Misof B, Rota-Stabelli O, Stadler PF. Bioinformatics methods for the comparative analysis of metazoan mito-­chondrial genome sequences. Molecular phylogenetics and evolution 69 (2013), 2, S. 320–327. DOI dx.doi.org/10.1016/j.ympev.2012.09.019
  • Bernt M, Braband A, Schier­water B, Stadler PF. Genetic aspects of mitochondrial genome evolution. Molecular phylo­genetics and evolution 69 (2013), Nr. 2, S. 328–338. DOI dx.doi.org/10.1016/j.ympev.2012.10.020
  • Bernt M, Donath A, Jühling F, Externbrink F, Florentz C, Fritzsch G, Pütz J, Middendorf M, Stadler PF. MITOS: improved de novo metazoan mitochondrial genome annotation. Molecular phylogenetics and evolution 69 (2013), Nr. 2, S. 313–319. DOI dx.doi.org/10.1016/j.ympev.2012.08.023
  • Biadglegne F, Tesfaye W, Anagaw B, Tessema B, Debebe T, Anagaw B, Mulu A, Sack U, Rodloff A.C. Tuberculosis lymphadenitis in Ethiopia. Japanese journal of infectious diseases : JJID 66 (2013), 4, S. 263–268.
  • Blumert C, Kalkhof S, Broche-Heidrich K, Kohajda T, von Bergen M, Horn F. Analysis of the STAT3 intercatome using in-situ biotinylation and SILAC. Journal of Proteomics. 94 (2013), S. 370–386. DOI dx.doi.org/10.1016/j.jprot.2013.08.021
  • Bodammer P, Kerkhoff C, Maletzki C, Lamprecht G. Bovine colostrum increases pore-forming claudin-2 protein expression but paradoxically not ion permeability possibly by a change of the intestinal cytokine milieu. PLoS One. 8 (2013), 5, e64210. DOI dx.doi.org/10.1371/journal.pone.0064210
  • Bodammer P, Zirzow E, Klammt S, Maletzki C, Kerkhoff C. Alteration of DSS-mediated immune cell redistribution in murine colitis by oral colostral immunoglobulin. BMC immunology. 14 (2013), e10. DOI dx.doi.org/10.1186/1471-2172-14-10
  • Boll K, Reiche K, Kasack K, Mörbt N, Kretzschmar AK, Tomm JM, Verhaegh G, Schalken J, von Bergen M, Horn F, Hackermüller J. MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma. Oncogene. 32 (2013), S. 277–285. DOI dx.doi.org/10.1038/onc.2012.55
  • Breitrück A, Sparmann G, Mitzner S, Kerkhoff C. Establishment of a novel extracorporeal bowel model to study luminal approaches to treat inflammatory bowel disease. Disease Models and Mechanisms. 6 (2013), 6, S. 1487–93. DOI dx.doi.org/10.1242/dmm.011734
  • Chabierski S, Makert GR, Kerzhner A, Barzon L, Fiebig P, Liebert UG, Papa A, Richner JM, Niedrig M, Diamond MS, Palù G, Ulbert S. Antibody responses in humans infected with newly emerging strains of West Nile Virus in Europe. PLoS One. 8 (2013), 6, e66507. DOI dx.doi.org/10.1371/journal.pone.0066507
  • Cynis H, Kehlen A, Haegele M, Hoffmann T, Heiser U, Fujii M, Shibazaki Y, Yoneyama H, Schilling S, Demuth HU. Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice. Int J Exp Pathol. 2013 Jun; 94(3):217–25. DOI dx.doi.org/10.1111/iep.12020 Epub 2013 Apr 8.
  • Dieterich C, Stadler PF. Computational biology of RNA interactions. Wiley interdisciplinary reviews. RNA. Online resource 4 (2013), Nr. 1, S. 107–120. DOI dx.doi.org/10.1002/wrna.1147
  • Dirnagl, U, Hakim A, MacLeod M, Fisher M, Howells D, Alan SM, Steinberg G, Planas A, Boltze J, Savitz S, Iadecola C. Meairs S. A concerted appeal for international cooperation in preclinical stroke research. Stroke. 44 (2013), 6, S. 1754–1760. DOI dx.doi.org/10.1161/STROKEAHA.113.000734
  • Doose G, Alexis M, Kirsch R, Findeis S, Langenberger D, Machne R, Mörl M, Hoffmann S, Stadler PF. Mapping the RNA-Seq trash bin: Unusual transcripts in prokaryotic transcriptome sequencing data. RNA biology 10 (2013), Nr. 7, S. 1204–1210. DOI dx.doi.org/10.4161/rna.24972
  • Faust D, Kletting S, Ueberham E, Dietrich C. Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells. Toxicology letters. 223 (2013), 1, S. 73–80. DOI dx.doi.org/10.1016/j.toxlet.2013.08.022
  • Fricke S, Hilger N, Fricke C, Schönfelder U, Behre G, Ruschpler P, Boldt A, Oelkrug C, Sack U, Emmrich F. Prevention of graft-versus-host-disease with preserved graft-versus-leukemia-effect by ex vivo and in vivo modulation of CD4+ T-cells. Cellular and Molecular Life Sciences. 2013 Sep 26. [Epub ahead of print]
  • Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, Lemere CA. Pyroglutamate-3 amyloid-beta deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models. Am J Pathol. 2013 Aug;183(2):369-81. DOI dx.doi.org/10.1016/j.ajpath.2013.05.005 Epub 2013 Jun 7.
  • Güttler BH, Cynis H, Seifert F, Ludwig HH, Porzel A, Schilling S. A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues. Amino Acids. 44 (2013), 4, S. 1205–14. DOI dx.doi.org/10.1007/s00726-012-1454-0
  • Hass J, Walton E, Kirsten H, Liu J, Priebe L, Wolf C, Karbalai N, Gollub R, White T, Roessner V, Müller KU, Paus T, Smolka MN, Schumann G, IMAGEN Consor­tium, Scholz M, Cichon S, Calhoun V, Ehrlich S. A genome-wide association study suggests novel loci associated with a Schizo­phrenia-related brain-based phenotype. PLoS One. 8 (2013), 6, e64872. DOI dx.doi.org/10.1371/journal.pone.0064872
  • Hellvard A, Maresz K, Schilling S, Graubner S, Heiser U, Jonsson R, Cynis H, Demuth HU, Potempa J, Mydel P. Glutaminyl cyclases as novel targets for the treatment of septic arthritis. Journal of Infectious Diseases. 207 (2013), 5, S. 768–77. DOI dx.doi.org/10.1093/infdis/jis729
  • Hodzic M, Naaldijk Y, Stolzing A. Regulating aging in adult stem cells with microRNA. Zeitschrift für Gerontologie und Geriatrie. 46 (2013), 7, S. 629–34. DOI dx.doi.org/10.1007/s00391-013-0531-7
  • Holland H, Xu LX, Ahnert P, Kirsten H, Koschny R, Bauer M, Schober R, Meixensberger J, Krupp W. Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma. Pathology – research and practice. 209 (2013), 9, S. 541–7. DOI dx.doi.org/10.1016/j.prp.2013.06.001
  • Hubicka J, Jost J, Long Y, Stadler PF, Yang L. Relations between graphs. Ars mathematica contemporanea 6 (2013), Nr. 2, S. 323–350.
  • Jiang SN, Park SH, Lee HJ, Zheng JH, Kim HS, Bom HS, Hong Y, Szardenings M, Shin MG, Kim SC, Ntziachristos V, Choy HE, Min JJ. Engineering of bacteria for the visualiza­tion of targeted delivery of a cytolytic anticancer agent. Molecular Therapy. 21 (2013), 11, S. 1985–95. DOI dx.doi.org/10.1038/mt.2013.183
  • Kehlen A, Haegele M, Menge K, Gans K, Immel UD, Hoang-Vu C, Klonisch T, Demuth HU. Role of glutaminyl cyclases in thyroid carcinomas. Endocr Relat Cancer. 2013 Feb 18;20(1):79-90. DOI dx.doi.org/10.1530/ERC-12-0053 Print 2013 Feb.
  • Kolenko P, Koch B, Rahfeld JU, Schilling S, Demuth HU, Stubbs MT. Structure of glutaminyl cyclase from Drosophila melanogaster in space group I4. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69 (Pt 4): 358-61. DOI dx.doi.org/10.1107/S1744309113005575 Epub 2013 Mar 28.
  • Langenberger D, Cakir MV, Hoffmann S, Stadler PF. Dicer-processed small RNAs: Rules and exceptions. Journal of experimental zoology. Part B, Molecular and developmental evolution 320B (2013), Nr. 1, S. 35–46. DOI dx.doi.org/10.1002/jez.b.22481
  • Lechner M, Marz M, Ihling C, Sinz A, Stadler PF, Krauss V. The correlation of genome size and DNA methylation rate in metazoans. Theory in Biosciences 132 (2013), Nr. 1, S. 47–60. DOI dx.doi.org/10.1007/s12064-012-0167-y
  • Lehmann J, Stadler PF, Krauss V. Near intron pairs and the metazoan tree. Molecular phylogenetics and evolution 66 (2013), Nr. 3, S. 811–823. DOI dx.doi.org/10.1016/j.ympev.2012.11.012
  • Lipfert J, Ödemis V, Wagner DC, Boltze J, Engele J. CXCR4 and CXCR7 form a functional receptor unit for SDF-1/CXCL12 in primary rodent microglia. Neuropathology and applied neurobiology. 39 (2013), 6, S. 667–80. DOI dx.doi.org/10.1111/nan.12015
  • Lison H, Happel MF, Schneider F, Baldauf K, Kerbstat S, Seelbinder B, Schneeberg J, Zappe M, Goldschmidt J, Budinger E, Schröder UH, Ohl FW, Schilling S, Demuth HU, Scheich H, Reymann KG, Rönicke R. Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death. Neurobiol Dis. 2014 Mar;63:62-73. DOI dx.doi.org/10.1016/j.nbd.2013.11.014 Epub 2013 Nov 27.
  • Lobsien D, Dreyer AY, Stroh A, Boltze J, Hoffmann KT. Imaging of VSOP labeled stem cells in agarose phantoms with susceptibility weighted and T2* weighted MR Imaging at 3T: determination of the detection limit. PLoS One. 8 (2013), 5, e62644. DOI dx.doi.org/10.1371/journal.pone.0062644
  • Mitzner S. Stellenwert der MARS-Dialyse beim Acute-on-chronic-Leberversagen. Zeitschrift für Gastroenterologie. 51 (2013), 10, S. 1193–4. DOI dx.doi.org/10.1055/s-0033-1350351
  • Mitzner SR, Gloger M, Henschel J, Koball S. Improvement of hemodynamic and inflammatory parameters by combined hemoadsorption and hemodiafiltration in septic shock: a case report. Blood Purification. 35 (2013),4, S. 314–5. DOI dx.doi.org/10.1159/000351206
  • Müller SA, Findeiß S, Pernitzsch SR, Wissenbach DK, Stadler PF, Hofacker IL, Bergen M. von, Kalkhof S. Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics. Journal of Proteomics 86 (2013), S. 27–42. DOI dx.doi.org/10.1016/j.jprot.2013.04.036
  • Pachernegg S, Joshi I, Muth-Köhne E, Pahl S, Münster Y, Terhag J, Karus M, Werner M, Ma-Högemeier ZL, Körber C, Grunwald T, Faissner A, Wiese S, Hollmann M. Undifferentiated embryonic stem cells express ionotropic glutamate receptor mRNAs. Frontiers in Neuroscience. 7 (2013), 241, 12 S. DOI dx.doi.org/10.3389/fncel.2013.00241
  • Pönisch W, Moll B, Bourgeois M, Andrea M, Schliwa T, Heyn S, Schmalfeld M, Edelmann T, Becker C, Hoffmann FA, Schwarzer A, Kreibich U, Egert M, Stiegler R, Krahl R, Remane Y, Bachmann A, Lindner T, Weid­hase L, Petros S, Fricke S, Vucinic V, Al Ali H, Niederwieser D. Bendamustine and prednisone in combination with bortezomib (BPV) in the treatment of patients with relapsed or refractory multiple myeloma and light chain-induced renal failure. Journal of Cancer Research and Clinical Oncology. 139 (2013), 11, S. 1937–46. DOI dx.doi.org/10.1007/s00432-013-1513-2
  • Ramsbeck D., Buchholz M., Koch B., Böhme S., Hoffmann T., Demuth H-U, Heiser U. Structure-activity relationships of benzimidazole-based glutaminyl cyclase inhibitors featuring a heteroaryl scaffold. Journal of Medicinal Chemistry.56 (2013), 17, S. 6613–25. DOI dx.doi.org/10.1021/jm4001709
  • Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J. RNAsnp: Efficient detection of local RNA secondary structure changes induced by SNPs. Human mutation 34 (2013), Nr. 4, S. 546–556. DOI dx.doi.org/10.1002/humu.22273
  • Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J. The RNAsnp web server: predicting SNP effects on local RNA secondary structure. Nucleic Acids Research 41 (2013), Nr. W1, S. W475–W479. DOI dx.doi.org/10.1093/nar/gkt291
  • Sack U, Barnett D, Demirel GY, Fossat C, Fricke S, Kafassi N, Nebe T, Psarra K, Steinmann J, Lambert C. Accreditation of flow cytometry in Europe. Cytometry B Clinical Cytometry. 84 B (2013), 3, S. 135–42. DOI dx.doi.org/10.1002/cyto.b.21079
  • Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR. Role of different replacement fluids during extracorporeal treatment in a pig model of sepsis. Therapeutic Apheresis and Dialysis. 17 (2013), 1, S. 84–92. DOI dx.doi.org/10.1111/j.1744-9987.2012.01103.x
  • Schreiber R, Luong N, Fan Z, Kuzyk A, Nickels PC, Zhang T, Smith DM, Yurke B, Kuang W, Govorov AO, Liedl T. Chiral plasmonic DNA nano­structures with switchable circular dichroism. Nature Communations. 4 (2013), 2948. DOI dx.doi.org/10.1038/ncomms3948
  • Smith D, Schüller V, Engst C, Rädler J, Liedl T. Nucleic acid nanostructures for biomedical applications. Nanomedicine. 8 (2013), 1, S. 105–21. DOI dx.doi.org/10.2217/nnm.12.184
  • Stolzing A, Haendeler J. Aging-mechanisms, models, and translation. Zeitschrift für Gerontologie und Geriatrie. 46 (2013), 7, S. 612. DOI dx.doi.org/10.1007/s00391-013-0528-2
  • Sun N, Hartmann R, Lecher J, Stoldt M, Funke SA, Gremer L, Ludwig HH, Demuth HU, Kleinschmidt M, Willbold D. Structural analysis of the pyroglutamate-modified isoform of the Alzheimer‘s disease-related amyloid-β using NMR spectroscopy. J Pept Sci. 2012 Nov;18(11):691-5. DOI dx.doi.org/10.1002/psc.2456 Epub 2012 Sep 24
  • Tessema B, Beer J, Merker M, Emmrich F, Sack U, Rodloff AC, Niemann S. Molecular epidemiology and trans­mission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia. BMC Infectious Diseases. 13 (2013), 131. DOI dx.doi.org/10.1186/1471-2334-13-131
  • Wachsmuth M, Findeiß S, Weissheimer N, Stadler PF, Mörl M. De novo design of a synthetic riboswitch that regulates transcription termination. Nucleic Acids Research 41 (2013), Nr. 4, S. 2541–2551. DOI dx.doi.org/10.1093/nar/gks1330
  • Wagner DC, Scheibe J, Glocke I, Weise G, Deten A, Boltze J, Kranz A. Object-based analysis of astroglial reaction and astrocyte subtype morphology after ischemic brain injury. Acta Neurobio­logiae Experimentals. 73 (2013), 1, S. 79–87.
  • Will S, Siebauer MF, Heyne S, Engelhardt J, Stadler PF, Reiche K, Backofen R. LocARNAscan: incorporating thermodynamic stability in sequence and structure-based RNA homology search. Algorithms for Molecular Biology. 8 (2013), 1, 14. DOI dx.doi.org/10.1186/1748-7188-8-14

Publications 2012

  • Arnold A, Naaldijk YM, Fabian C, Wirth H, Binder H, Nikkhah G, Armstrong L, Stolzing A. Reprogramming of Human Huntington Fibroblasts Using mRNA. ISRN Cell Biology, Volume 2012 (2012), Article ID 124878, 12 pages. DOI dx.doi.org/10.5402/2012/124878 Article
  • Averill MM, Kerkhoff C, Bornfeldt KE. S100A8 and S100A9 in cardiovascular biology and disease. Arterioscler Thromb Vasc Biol. 32 (2012), 2, S. 223-9. DOI dx.doi.org/10.1161/ATVBAHA.111.236927
  • Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, Saliba F, Sauerbruch T, Klammt S, Ockenga J, Pares A, Wendon J, Brünnler T, Kramer L, Mathurin P, Mata MD, Gasbarrini A, Müllhaupt B, Wilmer A, Laleman W, Eefsen M, Sen S, Zipprich A, Tenorio T, Pavesi M, Schmidt HH, Mitzner S, Williams R, Arroyo V. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: The RELIEF trial. Hepatology. 2012. DOI dx.doi.org/10.1002/hep.26185 [Epub ahead of print]
  • Beer S, Gomez T, Dallinger D, Momber I, Marnay C, Stadler M, Lai J. An economic analysis of used electric vehicle batteries integrated into commercial building microgrids. IEEE transactions on smart grid 3 (2012), 1, S.517-525. DOI dx.doi.org/10.1109/TSG.2011.2163091
  • Boltze J, Kleinschnitz C, Reymann KG, Reiser G, Wagner DC, Kranz A, Michalski D; the meeting contributors. Neurovascular pathophysiology in cerebral ischemia, dementia and the ageing brain - current trends in basic, translational and clinical research. Exp Transl Stroke Med. 4 (2012), 1:14. DOI dx.doi.org/10.1186/2040-7378-4-14
  • Boltze J, Reich DM, Hau S, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Kamprad M, Stahl T. Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo. Cell Transplant. 21 (2012), 4, S. 723-737. DOI dx.doi.org/10.3727/096368911X586783
  • Boltze J, Schmidt UR, Reich DM, Kranz A, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Förschler A, Schäbitz WR. Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats. Cell Transplant. 21 (2012), 6, S. 1199-211. DOI dx.doi.org/10.3727/096368911X589609
  • Burkhardt J, Kirsten H, Holland H, Krupp W, Ligges C, Quente E, Boltze J, Ahnert P, Wilcke A. Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort. Psychiatric Genetics. 22 (2012), 6, S. 307-308. DOI dx.doi.org/10.1097/YPG.0b013e328353aeae
  • Burkhardt J, Kirsten H, Wolfram G, Quente E, Ahnert P. Differential allelic expression of IL13 and CSF2 genes associated with asthma. Genetics and molecular biology, 35(2012), 3, S. 567-574. DOI dx.doi.org/10.1590/S1415-47572012005000055
  • Colley H, McArthur SL, Stolzing A, Scutt A. Culture on fibrin matrices maintains the colony-forming capacity and osteoblastic differentiation of mesenchymal stem cells. Biomed Mater. 7 (2012), 4:045015. DOI dx.doi.org/10.1088/1748-6041/7/4/045015
  • De Filette M, Ulbert S, Diamond M, Sanders NN. Recent progress in West Nile virus diagnosis and vaccination. Vet Res.43 (2012), 1, S. 16. DOI dx.doi.org/10.1186/1297-9716-43-16
  • Engelhardt J, Stadler PF. Hidden treasures in unspliced EST data. Theory in Biosciences 131 (2012), 1, S.49-57. DOI dx.doi.org/10.1007/s12064-012-0151-6
  • Fricke S, Fricke C, Oelkrug C, Blatz R, Schönfelder U, Niederwieser D, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR for the detection and characterisation of Aspergillus species. Mycoses. 55 (2012), 5, S. 416-25. DOI dx.doi.org/10.1111/j.1439-0507.2011.02161.x
  • Fricke S, Rothe K, Hilger N, Ackermann M, Oelkrug C, Fricke C, Schönfelder U, Niederwieser D, Emmrich F, Sack U. Allogeneic bone marrow grafts with high levels of CD4(+) CD25(+) FoxP3(+) T cells can lead to engraftment failure. Cytometry A. 81 (2012), 6, S. 476-88. DOI dx.doi.org/10.1002/cyto.a.22061
  • Fueldner C, Mittag A, Knauer J, Biskop M, Hepp P, Scholz R, Wagner U, Sack U, Emmrich F, Tárnok A, Lehmann J. Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry. Arthritis Res Ther. 14 (2012), 1:R8. DOI dx.doi.org/10.1186/ar3682
  • Fuellen G, Dengjel J, Hoeflich A, Hoeijemakers J, Kestler HA, Kowald A, Priebe S, Rebholz-Schuhmann D, Schmeck B, Schmitz U, Stolzing A, Sühnel J, Wuttke D, Vera J. Systems Biology and Bioinformatics in Aging Research: A Workshop Report. Rejuvenation Res. 15 (2012), 6, S. 631 -641. DOI dx.doi.org/10.1089/rej.2012.1360
  • Hellmuth M, Ostermeier L, Stadler PF. A survey on hypergraph products. Mathematics in Computer Science 6 (2012), 1, S.1-32. DOI dx.doi.org/10.1007/s11786-012-0109-6
  • Hellmuth M, Ostermeier L, Stadler PF. Diagonalized Cartesian products of S-prime graphs are S-prime. Discrete mathematics 312 (2012), 1, S.74-80. DOI dx.doi.org/10.1016/j.disc.2011.03.033
  • Hertel J, Bartschat S, Wintsche A, Otto C, Stadler PF. Evolution of the let-7 microRNA Family. RNA biology 9 (2012), 3, S.231-241. DOI dx.doi.org/10.4161/rna.9.3.18974
  • Hinz D, Bauer M, Röder S, Olek S, Huehn J, Sack U, Borte M, Simon JC, Lehmann I, Herberth G; for the LINA study group. Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year. Allergy. 67 (2012), 3, S. 380 - 389. DOI dx.doi.org/10.1111/j.1398-9995.2011.02767.x
  • Hinze A, Stolzing A. Microglia differentiation using a culture system for the expansion of mice non-adherent bone marrow stem cells. J Inflamm (Lond). 9 (2012), 1:12. DOI dx.doi.org/10.1186/1476-9255-9-12
  • Hofacker IL, Reidys CM, Stadler PF. Symmetric circular matchings and RNA folding. Discrete mathematics 312 (2012), 1, S.100-112. DOI dx.doi.org/10.1016/j.disc.2011.06.004
  • Holland H, Ahnert P, Koschny R, Kirsten H, Bauer M, Schober R, Meixensberger J, Fritzsch D, Krupp W. Detection of novel genomic aberrations in anaplastic astrocytomas by GTG-banding, SKY, locusspecific FISH, and high density SNP-array. Pathology, research and practice, 208 (2012), 6, S. 325-330. DOI dx.doi.org/10.1016/j.prp.2012.03.010
  • Johnson AA, Akman K, Calimport SR, Wuttke D, Stolzing A, de Magalhães JP. The role of DNA methylation in aging, rejuvenation, and age-related disease. Rejuvenation Res. 15 (2012), 5, S. 483-94. DOI dx.doi.org/10.1089/rej.2012.1324
  • Jühling F, Pütz J, Bernt M, Donath A, Middendorf M, Florentz C, Stadler PF. Improved systematic tRNA gene annotation allows new insights into the evolution of mitochondrial tRNA structures and into the mechanisms of mitochondrial genome rearrangements. Nucleic Acids Research 40 (2012), 7, S.2833-2845. DOI dx.doi.org/10.1093/nar/gkr1131
  • Jühling F, Putz J, Florentz C, Stadler PF. Armless mitochondrial tRNAs in enoplea (nematoda). RNA biology 9 (2012), 9, S.1161-1166. DOI dx.doi.org/10.4161/rna.21630
  • Kerkhoff C, Voss A, Scholzen TE, Averill MM, Zänker KS, Bornfeldt KE. Novel insights into the role of S100A8/A9 in skin biology. Exp Dermatol. 21 (2012), 11, S. 822 - 6. DOI dx.doi.org/10.1111/j.1600-0625.2012.01571.x
  • Kielstein JT, Beutel G, Fleig S, Steinhoff J, Meyer TN, Hafer C, Kuhlmann U, Bramstedt J, Panzer U, Vischedyk M, Busch V, Ries W, Mitzner S, Mees S, Stracke S, Nürnberger J, Gerke P, Wiesner M, Sucke B, Abu-Tair M, Kribben A, Klause N, Schindler R, Merkel F, Schnatter S, Dorresteijn EM, Samuelsson O, Brunkhorst R; Collaborators of the DGfN STEC-HUS registry. Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome: an analysis of the German STEC-HUS registry. Nephrol Dial Transplant. 27 (2012), 10, S. 3807-15. DOI dx.doi.org/10.1093/ndt/gfs394
  • Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatric Genetics. 22 (2012), 4, S. 216-217. DOI dx.doi.org/10.1097/YPG.0b013e32834c0c97
  • Klammt S, Wojak HJ, Mitzner A, Koball S, Rychly J, Reisinger EC, Mitzner S. Albumin-binding capacity (ABiC) is reduced in patients with chronic kidney disease along with an accumulation of protein-bound uraemic toxins. Nephrol Dial Transplant. 27 (2012), 6, S. 2377-83. DOI dx.doi.org/10.1093/ndt/gfr616
  • Klemm K, Mehta A, Stadler PF. Landscape encodings enhance optimization. PLoS one. Online journal 7 (2012), 4, Art. E34780. DOI dx.doi.org/10.1371/journal.pone.0034780
  • Klionsky DJ and 1269 others. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8 (2012), 4, S. 445 - 544. DOI dx.doi.org/10.4161/auto.19496
  • Koch H, Graneist C, Emmrich F, Till H, Metzger R, Aupperle H, Schierle K, Sack U, Boldt A. Xenogenic esophagus scaffolds fixed with several agents: comparative in vivo study of rejection and inflammation. J Biomed Biotechnol. 2012; 2012:948320. DOI dx.doi.org/10.1155/2012/948320
  • Kuhlmeier D, Sandetskaya N, Allelein S. Application of nanotechnology in miniaturized systems and its use in medical and food analysis. Recent Pat Food Nutr Agric. 4 (2012), 3, S. 187-99. DOI dx.doi.org/10.2174/2212798411204030187
  • Lange F, Sack U. Gelenkentzündungen : Modellsysteme für die Arthritisforschung. GIT Spezial BIOforum 1/2012, S. 28-30. GIT Labor-Fachzeitschrift 56 (2012), 6, S. 459-461. Artikel
  • Langenberger D, Pundhir S, Ekstrom CT, Stadler PF, Hoffmann S, Gorodkin J. deepBlockAlign: A tool for aligning RNA-seq profiles of read block patterns. Bioinformatics 28 (2012), 1, S.17-24. DOI dx.doi.org/10.1093/bioinformatics/btr598
  • Leichsenring A, Lange F. Tiermodelle in der präklinischen Forschung. GIT Labor-Fachzeitschrift 56 (2012), 12, S. 848–849. Artikel
  • Maletzki C, Bodammer P, Breitrück A, Kerkhoff C. S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma. Hepat Mon. 2012, 12 (10 HCC):e7240. DOI dx.doi.org/10.5812/hepatmon.7240
  • Michalski D, Heindl M, Kacza J, Laignel F, Küppers-Tiedt L, Schneider D, Grosche J, Boltze J, Löhr M, Hobohm C, Härtig W. Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation. Eur J Histochem. 2012, 56(2):e14. DOI dx.doi.org/10.4081/ejh.2012.14
  • Möller K, Stahl T, Boltze J, Wagner DC. Isolation of inflammatory cells from rat brain tissue after stroke. Exp Transl Stroke Med. 4 (2012), 1:20. DOI dx.doi.org/10.1186/2040-7378-4-20
  • Naaldijk Y, Staude M, Fedorova V, Stolzing A. Effect of different freezing rates during cryopreservation of rat mesenchymal stem cells using combinations of hydroxyethyl starch and dimethylsulfoxide. BMC Biotechnol. (2012) 12:49. DOI dx.doi.org/10.1186/1472-6750-12-49
  • Ostermeier L, Hellmuth M, Stadler PF. The Cartesian product of hypergraphs. Journal of Graph Theory 70 (2012), 2, S.180-196. DOI dx.doi.org/10.1002/jgt.20609
  • Otto C, Reiche K, Hackermüller J. Detection of differentially expressed segments in tiling array data. In: Bioinformatics 28 (2012), 11, S.1471-1479. DOI dx.doi.org/10.1093/bioinformatics/bts142
  • Otto C, Stadler PF, Hoffmann S. Fast and sensitive mapping of bisulfite-treated sequencing data. Bioinformatics 28 (2012), 13, S.1698-1704. DOI dx.doi.org/10.1093/bioinformatics/bts254
  • Pohler P, Lehmann J, Veneruso V, Tomm J, v. Bergen M, Lambrecht B, Kohn B, Weingart C, Müller TH, Seltsam A. Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model. Transfusion. 52 (2012), 11, S. 2414-26. DOI dx.doi.org/10.1111/j.1537-2995.2012.03583.x
  • Polchow B, Kebbel K, Schmiedeknecht G, Reichardt A, Henrich W, Hetzer R, Lueders C. Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks. J Transl Med. 2012; 10:98. DOI dx.doi.org/10.1186/1479-5876-10-98
  • Pösel C, Möller K, Fröhlich W, Schulz I, Boltze J, Wagner DC. Density gradient centrifugation compromises bone marrow mononuclear cell yield. PLoS One. 7 (2012), 12:e50293. DOI dx.doi.org/10.1371/journal.pone.0050293
  • Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR. Plasma separation by centrifugation and subsequent plasma filtration: impact on survival in a pig model of sepsis. Ther Apher Dial. 16 (2012), 3, S. 205-12. DOI dx.doi.org/10.1111/j.1744-9987.2011.01055.x
  • Sauer M, Haubner C, Mencke T, Nöldge-Schomburg G, Mitzner S, Altrichter J, Stange J. Impaired cell functions of hepatocytes incubated with plasma of septic patients. Inflamm Res. 61 (2012), 6, S. 609-16. DOI dx.doi.org/10.1007/s00011-012-0451-9
  • Schmidtke C, Findeiß S, Sharma CM, Kuhfuß J, Hoffmann S, Vogel J, Stadler PF, Bonas U. Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions. Nucleic Acids Research 40 (2012), 5, S.2020-2031. DOI dx.doi.org/10.1093/nar/gkr904
  • Scholbach J, Schulz A, Westphal F, Egger D, Wege AK, Patties I, Köberle M, Sack U, Lange F. Comparison of hematopoietic stem cells derived from fresh and cryopreserved whole cord blood in the generation of humanized mice. PLoS One. 7 (2012), 10:e46772. DOI dx.doi.org/10.1371/journal.pone.0046772
  • Stolzing A, Bauer E, Scutt A. Suspension cultures of bonemarrow-derived mesenchymal stem cells: effects of donor age and glucose level. Stem Cells Dev. 21 (2012), 14, S. 2718-23. DOI dx.doi.org/10.1089/scd.2011.0406
  • Stolzing A, Naaldijk Y, Fedorova V, Sethe S. Hydroxyethylstarch in cryopreservation - mechanisms, benefits and problems. Transfus Apher Sci. 46 (2012), 2, S. 137-47. DOI dx.doi.org/10.1016/j.transci.2012.01.007
  • Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B, Klaesner B, Zhu C, Schwarzmaier S, Meissner L, Mamrak U, Engel DC, Drzezga A, Patel RP, Blomgren K, Barthel H, Boltze J, Kuebler WM, Plesnila N. Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles. Circ Res. 110 (2012), 5, S. 727-38. DOI dx.doi.org/10.1161/CIRCRESAHA.111.253419
  • Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. Analysis of gene mutations associated with isoniazid, rifampicin and ethambutol resistance among Mycobacterium tuberculosis isolates from Ethiopia. BMC Infect Dis. 12 (2012) :37. DOi dx.doi.org/10.1186/1471-2334-12-37
  • Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. First- and second-line anti-tuberculosis drug resistance in Northwest Ethiopia. Int J Tuberc Lung Dis. 16 (2012), 6 S. 805-11. DOI dx.doi.org/10.5588/ijtld.11.0522
  • Tippmann SC, Ivanek R, Gaidatzis D, Scholer A, Hoerner L, Nimwegen E. van, Stadler PF, Stadler MB, Schubeler D. Chromatin measurements reveal contributions of synthesis and decay to steady-state mRNA levels. Molecular systems biology 8 (2012), Art.593. DOI dx.doi.org/10.1038/msb.2012.23
  • Voss A, Bode G, Kerkhoff C. Double-stranded RNA induces IL-8 and MCP-1 gene expression via TLR3 in HaCaTkeratinocytes. Inflamm Allergy Drug Targets. 11 (2012), 5, S. 397-405.
  • Voss A, Gescher K, Hensel A, Nacken W, Zänker KS, Kerkhoff C. Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor. FEBS Lett. 586 (2012), 2, S. 196-203. DOI dx.doi.org/10.1016/j.febslet.2011.12.022
  • Wagner DC, Bojko M, Peters M, Lorenz M, Voigt C, Kaminski A, Hasenclever D, Scholz M, Kranz A, Weise G, Boltze J. Impact of age on the efficacy of bone marrow mononuclear cell transplantation in experimental stroke. Exp Transl Stroke Med. 24(2012), 1:17. DOI dx.doi.org/10.1186/2040-7378-4-17
  • Wagner DC, Deten A, Härtig W, Boltze J, Kranz A. Changes in T2 relaxation time after stroke reflect clearing processes. Neuroimage.61 (2012), 4, S. 780-5. DOi dx.doi.org/10.1016/j.neuroimage.2012.04.023
  • Weise G, Stoll G. Magnetic resonance imaging of blood brain/nerve barrier dysfunction and leukocyte infiltration: closely related or discordant? Front Neurol. 2012; 3:178. DOi dx.doi.org/10.3389/fneur.2012.00178
  • Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H. Imaging genetics of FOXP2 in dyslexia. European Journal of Human Genetics, 20 (2012), 2, S. 224-229. DOI dx.doi.org/10.1038/ejhg.2011.160
  • Will S, Joshi T, Hofacker IL, Stadler PF, Backofen R. LocARNA-P: Accurate boundary prediction and improved detection of structural RNAs. RNA 18 (2012), 5, S.900-914. DOI dx.doi.org/10.1261/rna.029041.111
  • Wuttig D, Zastrow S, Füssel S, Toma MI, Meinhardt M, Kalman K, Junker K, Sanjmyatav J, Boll K, Hackermüller J, Rolle A, Grimm M-O, Wirth MP. CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases. International journal of cancer 131 (2012), 5, S.E693-E704. DOI dx.doi.org/10.1002/ijc.27419

Publications 2011

  • Boltze J, Kranz A, Wagner DC, Reymann K, Reiser G, Hess DC. Recent advances in basic and translational stroke research. Expert Rev Neurother. 2011 Feb;11(2):199-202.
  • Boltze J, Nitzsche B, Geiger KD, Schoon HA. Histopathological investigation of different MCAO modalities and impact of autologous bone marrow mononuclear cell administration in an Ovine stroke model. Translational Stroke Research 2 (2011), 3, S.279-293. DOI dx.doi.org/10.1007/s12975-011-0101-5
  • Boltze J, Reich DM, Hau S, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Kamprad M, Stahl T. Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo. Cell Transplant. 2011 Sep 16. DOI dx.doi.org/10.3727/096368911X586783 [Epub ahead of print]
  • Boltze J, Schmidt UR, Reich DM, Kranz A, Reymann KG, Strassburger M, Lobsien D, Wagner DC, Förschler A, Schäbitz WR. Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats. Cell Transplant. 2011 Dec 13. DOI dx.doi.org/10.3727/096368911X589609 [Epub ahead of print]
  • Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, Gingeras TR, Mattick JS. The reality of pervasive transcription. PLoS Biol. 9 (2011), 7, e1000625; discussion e1001102. DOI dx.doi.org/10.1371/journal.pbio.1000625
  • Efimenko A, Starostina E, Kalinina N, Stolzing A. (2011) Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. J Transl Med. Jan 18;9(1):10. DOI dx.doi.org/10.1186/1479-5876-9-10 Article
  • Eggenhofer F, Tafer H, Stadler PF, Hofacker IL. RNApredator : fast accessibility-based prediction of sRNA targets. Nucleic Acids Res. 39 (2011), Supl. 2, W149-54. DOI dx.doi.org/10.1093/nar/gkr467
  • Fangmann J, Kathrin Al-Ali H, Sack U, Kamprad M, Tautenhahn HM, Faber S, Hauss J, Niederwieser D, Lindner T, Bachmann A. Kidney transplant from the same donor without maintenance immunosuppression after previous hematopoietic stem cell transplant. Am J Transplant. 11 (2011), 1, S. 156 - 62. DOI dx.doi.org/10.1111/j.1600-6143.2010.03352.x
  • Fasold M, Langenberger D, Binder H, Stadler PF, Hoffmann S. DARIO: a ncRNA detection and analysis tool for next-generation sequencing experiments. Nucleic Acids Res. 39 (2011), Supl. 2, S. W112-7. DOI dx.doi.org/10.1093/nar/gkr357
  • Findeiss S, Engelhardt J, Prohaska SJ, Stadler PF. Protein-coding structured RNAs: A computational survey of conserved RNA secondary structures overlapping coding regions in drosophilids. Biochimie. 93 (2011), 11, S. 2019-23. DOI dx.doi.org/10.1016/j.biochi.2011.07.023
  • Findeiss S, Langenberger D, Stadler PF, Hoffmann S. Traces of post-transcriptional RNA modifications in deep sequencing data. Biol Chem. 2392 (2011), 4, S. 305-13. DOI dx.doi.org/10.1515/bc.2011.043
  • Fricke S, Fricke C, Oelkrug C, Blatz R, Schönfelder U, Niederwieser D, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR for the detection and characterisation of Aspergillus species. Mycoses. 2011 Dec 11. DOI dx.doi.org/10.1111/j.1439-0507.2011.02161.x [Epub ahead of print]
  • Grey D, Sack U, Scholz M, Knaack H, Fricke S, Oppel C, Luderer D, Fangmann J, Emmrich F, Kamprad M. Increased CD64 expression on polymorphonuclear neutrophils indicates infectious complications following solid organ transplantation. Cytometry A. 79 (2011), 6, S. 446 - 60. DOI dx.doi.org/10.1002/cyto.a.21049
  • Hinze A, Stolzing A. (2011) Differentiation of mouse bone marrow derived stem cells toward microglia. BMC Cell Biology. Aug 19;12(1):35. DOI dx.doi.org/10.1186/1471-2121-12-35 Article
  • Holland H, Livrea M, Ahnert P, Koschny R, Kirsten H, Meixensberger J, Bauer M, Schober R, Fritzsch D, Krupp W. Intracranial hemangiopericytoma: Case study with cytogenetics and genome wide SNP-A analysis. Pathol Res Pract. 2011 Feb 7. [Epub ahead of print]
  • Jühling F, Pütz J, Bernt M, Donath A, Middendorf M, Florentz C, Stadler PF. Improved systematic tRNA gene annotation allows new insights into the evolution of mitochondrial tRNA structures and into the mechanisms of mitochondrial genome rearrangements. Nucleic Acids Res. 2011 Dec 1. [Epub ahead of print] DOI dx.doi.org/10.1093/nar/gkr1131
  • Kehr S, Bartschat S, Stadler PF, Tafer H. PLEXY : efficient target prediction for box C/D snoRNAs. Bioinformatics. 27 (2011), 2, S. 279-80. DOI dx.doi.org/10.1093/bioinformatics/btq642
  • Kim M, Garant KA, Zur Nieden N, Alain T, Loken SD, Urbanski SJ, Forsyth PA, Rancourt D, Lee PW, Johnston RN. Attenuated reovirus displays oncolysis with reduced host toxicity. The British journal of cancer. 104 (2011), 2, S. 290 - 299. DOI dx.doi.org/10.1038/sj.bjc.6606053
  • Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatr Genet. 2011 Sep 20. DOI dx.doi.org/10.1097/YPG.0b013e32834c0c97 [Epub ahead of print].
  • Knauer J, Krupka I, Fueldner C, Lehmann J, Straubinger RK. Evaluation of the preventive capacities of a topically applied azithromycin formulation against Lyme borreliosis in a murine model. J Antimicrob Chemother. 66 (2011), 12, S. 2814 - 2822. DOI dx.doi.org/10.1093/jac/dkr371
  • Krakauer DC, Collins JP, Erwin D, Flack JC, Fontana W, Laubichler MD, Prohaska SJ, West GB, Stadler PF. The challenges and scope of theoretical biology. J Theor Biol. 276 (2011), 1, S. 269-76. DOI dx.doi.org/10.1016/j.jtbi.2011.01.051
  • Lechner M, Findeiss S, Steiner L, Marz M, Stadler PF, Prohaska SJ. Proteinortho : detection of (co-)orthologs in large-scale analysis. BMC Bioinformatics. 12 (2011), 124, 9 S. DOI dx.doi.org/10.1186/1471-2105-12-124
  • Marz M, Stadler PF. RNA interactions. Adv Exp Med Biol. 722 (2011), S. 20-38. DOI dx.doi.org/10.1007/978-1-4614-0332-6_2
  • Menzel P, Stadler PF, Gorodkin J. MaxAlike : maximum likelihood-based sequence reconstruction with application to improved primer design for unknown sequences. Bioinformatics. 27 (2011), 3, S. 317-25. DOI dx.doi.org/10.1093/bioinformatics/btq651
  • Michalski D, Pelz J, Weise C, Kacza J, Boltze J, Grosche J, Kamprad M, Schneider D, Hobohm C, Härtig W. Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke. Exp Transl Stroke Med. 3 (2011), 5, 9 S. DOI dx.doi.org/10.1186/2040-7378-3-5
  • Mocker K, Holland H, Ahnert P, Schober R, Bauer M, Kirsten H, Koschny R, Meixensberger J, Krupp W. Multiple meningioma with different grades of malignancy: case report with genetic analysis applying single-nucleotide polymorphism array and classical cytogenetics. Pathol Res Pract. 2011 Jan 15;207(1):67-72.
  • Oschatz C, Maas C, Lecher B, Jansen T, Björkqvist J, Tradler T, Sedlmeier R, Burfeind P, Cichon S, Hammerschmidt S, Müller-Esterl W, Wuillemin WA, Nilsson G, Renné T. Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity. 34 (2011), 2, S. 258-68. DOI dx.doi.org/10.1016/j.immuni.2011.02.008
  • Otto C, Hoffmann S, Gorodkin J, Stadler PF. Fast local fragment chaining using sum-of-pair gap costs. Algorithms Mol Biol. 6 (2011), 4, 8 S. DOI dx.doi.org/10.1186/1748-7188-6-4
  • Paulsen K, Tauber S, Timm J, Goelz N, Dumrese C, Stolzing A, Hass R, Ullrich O. (2011) The cannabinoid receptors agonist WIN55212-2 inhibits macrophageal differentiation and alters expression and phosphorylation of cell cycle control proteins. Cell Commun Signal. Dec 28;9(1):33.
  • Perseke M, Hetmank J, Bernt M, Stadler PF, Schlegel M, Bernhard D. The enigmatic mitochondrial genome of Rhabdopleura compacta (Pterobranchia) reveals insights into selection of an efficient tRNA system and supports monophyly of Ambulacraria. BMC Evol Biol. 11 (2011), 134, 12 S. DOI dx.doi.org/10.1186/1471-2148-11-134
  • Raincrow JD, Dewar K, Stocsits C, Prohaska SJ, Amemiya CT, Stadler PF, Chiu CH. Hox clusters of the bichir (Actinopterygii, Polypterus senegalus) highlight unique patterns of sequence evolution in gnathostome phylogeny. J Exp Zool B Mol Dev Evol. 16 (2011), 6, S. 451-64. DOI dx.doi.org/10.1002/jez.b.21420
  • Reidys CM, Huang FW, Andersen JE, Penner RC, Stadler PF, Nebel ME. Topology and prediction of RNA pseudoknots. Bioinformatics. 27 (2011), 8, S. 1076-85. DOI dx.doi.org/10.1093/bioinformatics/btr090
  • Riegelsberger UM, Deten A, Pösel C, Zille M, Kranz A, Boltze J, Wagner DC. Intravenous human umbilical cord blood transplantation for stroke: impact on infarct volume and caspase-3-dependent cell death in spontaneously hypertensive rats. Exp Neurol. 2011 Jan;227(1):218-23. Epub 2010 Nov 16.
  • Roesler U, Szabo I, Matthies C, Albrecht K, Leffler M, Scherer K, Nöckler K, Lehmann J, Methner U, Hensel A, Truyen U. Comparing validation of four ELISA-systems for detection of Salmonella derby- and Salmonella infantis-infected pigs. Berl Munch Tierarztl Wochenschr. 124 (2011), 7-8, S. 265-71. DOI dx.doi.org/10.2376/0005-9366-124-265
  • Rose D, Hiller M, Schutt K, Hackermüller J, Backofen R, Stadler PF. Computational discovery of human coding and non-coding transcripts with conserved splice sites. Bioinformatics. 27 (2011), 14, S. 1894-900. DOI dx.doi.org/10.1093/bioinformatics/btr314
  • Rupf S, Idlibi AN, Marrawi FA, Hannig M, Schubert A, von Mueller L, Spitzer W, Holtmann H, Lehmann A, Rueppell A, Schindler A. Removing biofilms from microstructured titanium ex vivo: a novel approach using atmospheric plasma technology. PLoS One.6 (2011), 10, e25893, 9 S. DOI dx.doi.org/10.1371/journal.pone.0025893
  • Schneeweiss A, Chabierski S, Salomo M, Delaroque N, Al-Robaiy S, Grunwald T, Bürki K, Liebert UG, Ulbert S. A DNA vaccine encoding the E protein of West Nile Virus is protective and can be boosted by recombinant domain DIII. Vaccine, 29 (2011), S. 6352-6357.
  • Schubert K, Polte T, Bönisch U, Schader S, Holtappels R, Hildebrandt G, Lehmann J, Simon JC, Anderegg U, Saalbach A. Thy-1 (CD90) regulates the extravasation of leukocytes during inflammation. Eur J Immunol. 41 (2011), 3, S. 645 - 656. DOI dx.doi.org/10.1002/eji.201041117
  • Skardelly M, Gaber K, Burdack S, Scheidt F, Hilbig H, Boltze J, Förschler A, Schwarz S, Schwarz J, Meixensberger J, Schuhmann MU. Long-term benefit of human fetal neuronal progenitor cell transplantation in a clinically adapted model after traumatic brain injury. J Neurotrauma. 28 (2011), 3, S. 401-14. DOI dx.doi.org/10.1089/neu.2010.1526
  • Smith DM, Schüller V, Forthmann C, Schreiber R, Tinnefeld P, Liedl T. A structurally variable hinged tetrahedron framework from DNA origami. J. Nuc. Acid., 2011. DOI dx.doi.org/10.4061/2011/360954
  • Stolzing A, Colley H, Scutt A. (2011) Effect of age and diabetes on the response of mesenchymal progenitor cells to fibrin matrices. Int J Biomater. 2011; 378034. Epub 2011 Dec 13. DOI dx.doi.org/10.1155/2011/378034 Article
  • Tafer H, Amman F, Eggenhofer F, Stadler PF, Hofacker IL. Fast accessibility-based prediction of RNA-RNA interactions. Bioinformatics. 27 (2011), 14, S. 1934-40. DOI dx.doi.org/10.1093/bioinformatics/btr281
  • Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B, Klaesner B, Zhu C, Schwarzmaier S, Meissner L, Mamrak U, Engel DC, Drzezga A, Patel RP, Blomgren K, Barthel H, Boltze J, Kuebler WM, Plesnila N. Inhalation of nitric oxide prevents Ischemic brain damage in experimental stroke by selective dilatation of Collateral Arterioles. Circ Res. 2011 Dec 29. DOI dx.doi.org/10.1161/CIRCRESAHA.111.253419 [Epub ahead of print]
  • Tessema B, Beer J, Emmrich F, Sack U, Rodloff AC. Rate of recovery of Mycobacterium tuberculosis from frozen acid-fast-bacillus smear-positive sputum samples subjected to long-term storage in Northwest Ethiopia. J Clin Microbiol. 49 (2011), 7, S. 2557 - 61. DOI dx.doi.org/10.1128/JCM.00059-11
  • Tramontano A, Donath A, Bernhart SH, Reiche K, Böhmdorfer G, Stadler PF, Bachmair A. Deletion analysis of the 3' long terminal repeat sequence of plant retrotransposon Tto1 identifies 125 base pairs redundancy as sufficient for first strand transfer. Virology. 412 (2011), 1, 75 - 82. DOI dx.doi.org/10.1016/j.virol.2010.12.059
  • Ulbert S. West Nile Virus: The Complex Biology of an Emerging Pathogen. Intervirology, 54 (2011), S. 171-184.
  • Ullrich A, Rohrschneider M, Scheuermann G, Stadler PF, Flamm C. In silico evolution of early metabolism. Artif Life. 17 (2011), 2, S. 87-108. DOI dx.doi.org/10.1162/artl_a_00021
  • Wagner DC, Riegelsberger UM, Michalk S, Härtig W, Kranz A, Boltze J. Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic. Brain Res. 2011 Mar 24;1381:237-42. Epub 2011 Jan 20.
  • Washietl S, Findeiss S, Müller SA, Kalkhof S, von Bergen M, Hofacker IL, Stadler PF, Goldman N. RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data. RNA. 17 (2011), 4, S. 578-94. DOI dx.doi.org/10.1261/rna.2536111
  • Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H. Imaging genetics of FOXP2 in dyslexia. Eur J Hum Genet. 20 (2012), 2, S. 224-9. DOI dx.doi.org/10.1038/ejhg.2011.160
  • Wuttig D, Zastrow S, Füssel S, Toma MI, Meinhardt M, Kalman K, Junker K, Sanjmyatav J, Boll K, Hackermüller J, Rolle A, Grimm MO, Wirth MP. CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases. Int J Cancer. 2011 Dec 31. DOI dx.doi.org/10.1002/ijc.27419 [Epub ahead of print]
  • zu Siederdissen CH, Bernhart SH, Stadler PF, Hofacker IL. A folding algorithm for extended RNA secondary structures. Bioinformatics. 27 (2011), 13, S. i129-36. DOI dx.doi.org/10.1093/bioinformatics/btr220

Publications 2010

  • Al-Robaiy S, Dihazi H, Kacza J, Seeger J, Schiller J, Huster D, Knauer J, Straubinger RK. Metamorphosis of Borrelia burgdorferi organisms – RNA, lipid and protein composition in context with the spirochetes’ shape. Journal of Basic Microbiology. 50 (2010), Sup. 1, S. 5–17.
  • Amemiya CT, Powers TP, Prohaska SJ, Grimwood J, Schmutz J, Dickson M, Miyake T, Schoenborn MA, Myers R, Ruddle FH, Stadler PF. Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome. Proceedings of the National Academy of Sciences of the United States of America. 107 (2010), 8, S. 3622–3627.
  • Arnold C, Stadler PF. Polynomial algorithms for the Maximal Pairing Problem: efficient phylogenetic targeting on arbitrary trees. Algorithms for molecular biology. 5 (2010), 25, 10 S. DOI dx.doi.org/10.1186/1748-7188-5-25
  • Bermudez-Santana C, Attolini CSO, Kirsten T, Engelhardt J, Prohaska SJ, Steigele S, Stadler PF. Genomic organization of eukaryotic tRNAs. BMC genomics. 11 (2010), 270, 14 S. DOI dx.doi.org/10.1186/1471-2164-11-270
  • Boria I, Gruber A, Tanzer A, Bernhart SH, Lorenz R, Müller MM, Hofacker IL, Stadler PF. Nematode sbRNAs: homologs of vertebrate Y RNAs. Journal of molecular evolution. 70 (2010), 4, S. 346–358.
  • Chung NP, Breun SK, Bashirova A, Baumann JG, Martin TD, Karamchandani JM, Rausch JW, Le Grice SF, Wu L, Carrington M, Kewalramani VN. HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbo­hydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN). J Biol Chem. 285 (2010), 3, S. 2100–2112.
  • Dienelt A, zur Nieden NI. Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation. Stem Cells Dev. 2010 Nov 30 [Epub ahead of print]. DOI dx.doi.org/10.1089/scd.2010.025
  • Fasold M, Stadler PF, Binder H. G-stack modulated probe intensities on expression arrays – sequence corrections and signal calibration. BMC bioinformatics. 11 (2010), 207, 24 S. DOI dx.doi.org/10.1186/1471-2105-11-207
  • Findeiß S, Schmidtke C, Stadler PF, Bonas U. A novel family of plasmid-transferred anti-sense ncRNAs. RNA biology. 7 (2010), 2, S. 120–124. DOI dx.doi.org/10.4161/rna.7.2.11184
  • Fricke S, Fricke C, Oelkrug C, Hilger N, Schönfelder U, Kamprad M, Lehmann J, Boltze J, Emmrich F, Sack U. Characterization of murine non-adherent bone marrow cells leading to recovery of endogenous hematopoiesis. Cell Mol Life Sci. 67 (2010), 23, S. 4095–4106.
  • Fricke S, Fricke C, Schimmelpfennig C, Oelkrug C, Schönfelder U, Blatz R, Zilch C, Faber S, Hilger N, Ruhnke M, Rodloff AC. A real-time PCR assay for the differentiation of Candida species. J Appl Microbiol. 109 (2010), 4, S 1150–1158.
  • Gessner C, Rechner B, Hammerschmidt S, Kuhn H, Hoheisel G, Sack U, Ruschpler P, Wirtz H. Angiogenic markers in breath condensate identify non-small cell lung cancer. Lung Cancer, 68 (2010), 2, S. 177–184.
  • Hemdan NY, Birkenmeier G, Wichmann G, Abu El-Saad A, Krieger T, Conrad K, Sack U. Interleukin-17-producing T helper cells in autoimmunity. Autoimmunity Reviews, 9 (2010), 11, S. 785–792.
  • Hinz D, Simon JC, Maier-Simon C, Milkova L, Röder S, Sack U, Borte M, Lehmann I, Herberth G. Reduced maternal regulatory T cell numbers and increased T helper type 2 cytokine production are associated with elevated levels of immunoglobulin E in cord blood. Clinical and Experimental Allergy. 40 (2010), 3, S. 419–426.
  • Hofacker I, Flamm C, Heine C, Wolfinger MT, Scheuermann G, Stadler PF. BarMap: RNA folding on dynamic energy landscapes, RNA. 16 (2010), 7, S. 1308–1316.
  • Huang FWD, Qin J, Reidys CM, Stadler PF. Target prediction and a statistical sampling algorithm for RNA-RNA interaction. Bioinformatics. 26 (2010), 2, S. 175–181.
  • Kranz A, Wagner DC, Kamprad M, Scholz M, Schmidt UR, Nitzsche F, Aberman Z, Emmrich F, Riegelsberger UM, Boltze J. Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats. Brain Res, 1315 (2010), S. 128–36.
  • Lehmann J, Stadler PF, Eisenhardt C, Krauss V. Some novel intron positions in conserved Drosophila genes are caused by intron sliding or tandem duplication. BMC evolutionary biology. 10 (2010), 156, 15 S. DOI dx.doi.org/10.1186/1471-2148-10-156
  • Lenz D, Barten MJ, Hiller S, Tarnok A, Sack U. Regenerative and predictive medicine of cardiovascular disease: the 9th Leipziger Workshop and the 2nd International Workshop on slide based cytometry. Cytom Part A, 64 (2005), 2, S. 110-114.
  • Lindner I. et al. alpha 2-Macroglobulin Inhibits the Malignant Properties of Astrocytoma Cells by Impeding beta-Catenin Signaling. Cancer Research, v. 70 (2010), no. 1, p. 277–287.
  • Marz M, Vanzo N, Stadler PF. Temperature-dependent structural variability of RNAs: spliced leader RNAs and their evolutionary history. Journal of bioinformatics and computational biology. 8 (2010), 1, S. 1–17.
  • Mühle A, Mühle C, Amann K, Dötsch J, Nüsken KD, Boltze J, Schneider H. No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers. Pediatr Nephrol. 25 (2010), 9, S. 1653–61.
  • Müller M, Lutter D, Püschel AW. Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. J Cell Sci. 123 (2010), Pt 2, S. 286–94.
  • Perseke M, Bernhard D, Fritzsch G, Brümmer F, Stadler PF, Schlegel M. Mitochondrial genome evolution in Ophiuroidea, Echinoidea, and Holothuroidea: insights in phylogenetic relationships of Echinodermata. Molecular phylogenetics and evolution. 56 (2010), 1, S. 201–211.
  • Prohaska SJ, Stadler PF, Krakauer DC. Innovation in gene regulation: the case of chromatin computation. Journal of theoretical biology. 265 (2010), 1, S. 27–44.
  • Riester M, Stadler PF, Klemm K. Reconstruction of pedigrees in clonal plant populations. Theoretical population biology. 78 (2010), 2, S. 109–117.
  • Rupf S, Lehmann A, Hannig M, Schafer B, Schubert A, Feldmann U, Schindler A. Killing of adherent microbes by a non-thermal atmospheric plasma jet. J Med Microbiol. 59 (2010), Pt 2, S. 206–12.
  • Schneeweiss A, Buyens K, Giese M, Sanders N, Ulbert S. Synergistic effects between natural histone mixtures and polyethylenimine in non-viral gene delivery in vitro. Int J Pharm. 400 (2010), 1–2, S. 86–95.
  • Sharma C, Hoffmann S, Darfeuille F, Reignier J, Findeiß S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J. The primary transcriptome of the major human pathogen Helicobacter pylori. Nature. 464 (2010), 7286, S. 250–255.
  • Stadler BM, Stadler PF. Combinatorial vector fields and the valley structure of fitness landscapes. Journal of mathematical biology. 61 (2010), 6, S. 877–898.
  • Stolzing A, Sellers D, Llewelyn O, Scutt A. Diabetes induced changes in rat mesenchymal stem cells. Cells Tissues Organs. 191 (2010), 6, S. 453–65.
  • Tafer H, Kehr S, Hertel J, Hofacker IL, Stadler PF. RNAsnoop : efficient target prediction for H/ACA snoRNAs. Bioinformatics. 26 (2010), 5, S. 610–616.
  • Taiani JT, Krawetz RJ, zur Nieden NI, Wu YE, Kallos MS, Matyas JR, Rancourt DE. Reduced Differentiation Efficiency of Murine Embryonic Stem Cells in Stirred Suspension Bioreactors. Stem Cell Dev. (2010), 7, S. 989–998.
  • Tessema B, Biadglegne F, Mulu A, Getachew A, Emmrich F, Sack U. Magnitude and determinants of nonadherence and nonreadiness to highly active antiretroviral therapy among people living with HIV/AIDS in Northwest Ethiopia: a cross-sectional study. AIDS research and therapy, 7 (2010), 2, 8 S. DOI dx.doi.org/10.1186/1742-6405-7-2
  • Tessema B, Yismaw G, Kassu A, Amsalu A, Mulu A, Emmrich F, Sack U. Seroprevalence of HIV, HBV, HCV and syphilis infections among blood donors at Gondar University Teaching Hospital, Northwest Ethiopia: declining trends over a period of five years. BMC Infectious Diseases, 10 (2010), 111, 7 S. DOI dx.doi.org/10.1186/1471-2334-10-111
  • Yerebakan C, Klopsch C, Niefeldt S, Zeisig V, Vollmar B, Liebold A, Sandica E, Steinhoff G. Acute and chronic response of the right ventricle to surgically induced pressure and volume overload – an analysis of pressure-volume relations. Interact Cardiovasc Thorac Surg. 10 (2010), 4, S. 519–25.
  • Yerebakan C, Sandica E, Prietz S, Klopsch C, Ugurlucan M, Kaminski A, Abdija S, Lorenzen B, Boltze J, Nitzsche B, Egger D, Barten M, Furlani D, Ma N, Vollmar B, Liebold A, Steinhoff G. Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload. Cell Transplant, 18 (2009), 8, S. 855-68.
  • zur Nieden NI, Baumgartner L. Assessing developmental osteotoxicity of chlorides in the embryonic stem cell test. Reprod Toxicol. 30 (2010), 2, S. 277–283.
  • zur Nieden NI, Davis LA, Rancourt DE. Comparing three novel endpoints for developmental osteotoxicity in the embryonic stem cell test. Toxicol Appl Pharmacol. 247 (2010), 2, S. 91–97.
  • zur Nieden NI, Davis LA, Rancourt DE. Monolayer cultivation of osteoprogenitors shortens duration of the embryonic stem cell test while reliably predicting developmental osteotoxicity. Toxicology.277 (2010), 1–3, S. 66–73.

Publications 2009

  • Althues H, Pötschke P, Kim G M, Kaskel S. Structure and Mechanical Properties of Transparent ZnO/PBDMA Nanocomposites. J Nanosci Nanotechno, 9 (2009), 4, S. 2739-2745.
  • Aupperle H, Thielebein J, Kiefer B, März I, Dinges G, Schoon HA, Schubert A. Expression of genes encoding matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in normal and diseased canine mitral valves. J Comp Pathol, 140 (2009), 4, S. 271-277.
  • Borte S, Liebert UG, Borte M, Sack U. Efficacy of measles, mumps and rubella revaccination in children with juvenile idiopathic arthritis treated with methotrexate and etanercept. Rheumatology, 48 (2009), 2, S. 144-148.
  • Borte S, Pan-Hammarstrom Q, Liu C, Sack U, Borte M, Wagner U, Graf D, Hammarström L. Interleukin-21 restores immunoglobulin production ex vivo in patients with common variable immunodeficiency and selective IgA deficiency. Blood, 114 (2009), 19, S. 4089-4098.
  • Burkhardt J, Petit-Teixeira E, Teixeira VH, Kirsten H, Garnier S, Ruehle S, Oeser C, Wolfram G, Scholz M, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Pascual-Salcedo D, Bombardieri S, Dequeker J, Radstake TR, Van Riel P, van de Putte L, Bardin T, Prum B, Buchegger-Podbielski U, Emmrich F, Melchers I, Cornelis F, Ahnert P. Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis. J Rheumatol, 36 (2009), 10, S.2149-2157.
  • Conant G, Stadler PF. Solvent exposure imparts similar selective pressures across a range of yeast proteins. Mol Biol Evol, 26 (2009), 5, S. 1155-1161.
  • Fisher M, Feuerstein G, Howells DW, Hurn PD, Kent TA, Savitz SI, Lo EH; STAIR Group. Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke, 40 (2009), 6, S. 2244-2250.
  • Fricke S, Ackermann M, Stolzing A, Schimmelpfennig C, Hilger N, Jahns J, Hildebrandt G, Emmrich F, Ruschpler P, Pösel C, Kamprad M, Sack U. Allogeneic non-adherent bone marrow cells facilitate hematopoietic recovery but do not lead to allogeneic engraftment. PLoS One  (2009), Jul 7, 4(7), e6157.
  • Fricke S, Fricke C, Schimmelpfennig C, Oelkrug C, Schönfelder U, Blatz R, Faber S, Zilch C, Hilger N, Ruhnke M, Rodloff A. New Real-time PCR assay for the differentiation of Candida species. Appl Microbiol (2009) (accepted JAM-2009-2135).
  • Härtig W, Reichenbach A, Voigt C, Boltze J, Bulavina L, Schuhmann MU, Seeger J, Schusser GF, Freytag C, Grosche J. Triple fluorescence labelling of neuronal, glial and vascular markers revealing pathological alterations in various animal models. J Chem Neuroanat, 37 (2009), 2, S. 128-138.
  • Heinrich A, Riethmüller D, Gloger M, Schusser GF, Giese M, Ulbert S. RNA interference protects horse cells in vitro from infection with Equine Arteritis Virus. Antivir Res, 81 (2009), 3, S. 209-216.
  • Heintz D, Gallien S, Wischgoll S, Ullmann AK, Schaeffer C, Kretzschmar AK, van Dorsselaer A, Boll M. Differential membrane proteome analysis reveals novel proteins involved in the degradation of aromatic compounds in Geobacter metallireducens. Mol Cell Proteomics, 8 (2009), 9, S. 2159-2169.
  • Hellmuth M, Imrich W, Klöckl W, Stadler PF. Approximate graph products. Eur J Combin, 30 (2009), 5, S. 1119-1133.
  • Herberth G, Gubelt R, Röder S, Krämer U, Schins RP, Diez U, Borte M, Heinrich J, Wichmann HE, Herbarth O, Lehmann I, LISA plus study group. Increase of inflammatory markers after indoor renovation activities: the LISA birth cohort study. Pediatr Allergy Immu, 20 (2009), 6, S. 563-570.
  • Hertel J, De Jong D, Marz M, Rose D, Tafer H, Tanzer A, Schierwater B, Stadler PF. Non-coding RNA annotation of the genome of Trichoplax adhaerens. Nucleic Acids Res, 37 (2009), 5, S. 1602-1615.
  • Hoffmann S, Otto C, Kurtz S, Sharma CM, Khaitovich P, Vogel J, Stadler PF, Hackermüller J. Fast Mapping of Short Sequences with Mismatches, Insertions and Deletions Using Index Structures. PLoS Comput Biol, 5 (2009), 5(9), e1000502.
  • Jaen O, Petit-Teixeira E, Kirsten H, Ahnert P, Semerano L, Pierlot C, Cornelis F, Boissier MC, Falgarone G; European Consortium on Rheumatoid Arthritis Families. No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis. Arthritis Res Ther. 2009;11(1):R5. Epub 2009 Jan 13.
  • Kaczkowski B, Torarinsson E, Reiche K, Havgaard JH, Stadler PF, Gorodkin J. Structural profiles of human miRNA families from pairwise clustering. Bioinformatics, 25 (2009), 3, S. 291-294.
  • Kirsten H, Burkhardt J, Hantmann H, Hunzelmann N, Vaith P, Ahnert P, Melchers I. 5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population. Arthritis Res Ther, 11 (2009), 2, S. 403.
  • Kirsten H, Petit-Teixeira E, Hantmann H, Reichardt J, Burkhardt J, Emmrich F, Cornelis F, Ahnert P. A family-based study does not support the association of a functional polymorphism in the gene for endothelial nitric oxide synthase with risk for rheumatoid arthritis. Scand J Rheumatol, 38 (2009), 4, S. 320-321.
  • Kirsten H, Petit-Teixeira E, Scholz M, Hasenclever D, Hantmann H, Heider D, Wagner U, Sack U, Hugo Teixeira V, Prum B, Burkhardt J, Pierlot C, Emmrich F, Cornelis F, Ahnert P. Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study. Arthritis Res Ther, 11 (2009), 3, R60.
  • Krämer U, Sugiri D, Ranft U, Krutmann J, von Berg A, Berdel D, Behrendt H, Kuhlbusch T, Hochadel M, Wichmann HE, Heinrich J, GINIplus and LISAplus study groups. Eczema, respiratory allergies, and traffic-related air pollution in birth cohorts from small-town areas. J Dermatol Sci, 56 (2009), 2, S. 99-105.
  • Krupka I, Knauer J, Lorentzen L, O‘Connor TP, Saucier J, Straubinger RK. Borrelia burgdorferi sensu lato species in Europe induce diverse immune responses against C6 peptides in infected mice. Clin Vaccine Immunol, 16 (2009), 11, S. 1546-1562.
  • Lee SM, Grass G, Kim G M, Dresbach C, Zhang L, Gösele U, Knez M. Low-temperature ZnO atomic layer deposition on biotemplates: flexible photocatalytic ZnO structures from Eggshell Membranes. Phys Chem Chem Phys, 11 (2009), 19, S. 3608-3614.
  • Meier H, Bullinger J, Marx G, Deten A, Horn LC, Rassler B, Zimmer HG, Briest W. Crucial role of interleukin-6 in the development of norepinephrine-induced left ventricular remodeling in mice. Cell Physiol Biochem, 23 (2009), 3-4, S. 327-334.
  • Quintana L, zur Nieden NI, Semino CE. Morphogenetic and regulatory mechanisms during devel­opmental chondrogenesis. Tissue Eng Pt B-Rev, 15 (2009), 1, S. 29-41.
  • Sack U, Conrad K, Csernok E, Frank I, Hiepe F, Krieger T, Kromminga A, Landenberg P, Messer G, Witte T, Mierau R, die deutsche EASI-Gruppe (European Autoimmunity Standardization Initiative). Autoantikörpernachweis mittels indirekter Immunfluoreszenz an HEp-2-Zellen. Deut Med Wochenschr, 134 (2009), 24, S. 1278-1282.
  • Sack U, Conrad K, Csernok E, Frank I, Hiepe F, Krieger T, Kromminga A, von Landenberg P, Messer G, Witte T, Mierau R, German EASI (European Autoimmunity Standardization Initiative). Autoantibody detection using indirect immunofluorescence on HEp-2 cells. Ann NY Acad Sci, 1173 (2009), S. 166-73.
  • Saver JL, Albers GW, Dunn B, Johnston KC, Fisher M, STAIR VI Consortium. Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials. Stroke, 40 (2009), 7, S. 2594-2600.
  • Scheibye-Alsing K, Hoffmann S, Frankel A, Jensen P, Stadler PF, Mang Y, Tommerup N, Gilchrist MJ, Nygard AB, Cirera S, Jorgensen CB, Fredholm M, Gorodkin J. Sequence assembly: review. Comput Biol Chem, 33 (2009), 2, S. 121-136.
  • Schlomann U, Schwamborn JC, Müller M, Fässler R, Püschel AW. The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase. J Cell Sci. 2009 Jun 15;122(Pt 12):2034-42. Epub 2009 May 19.
  • Scholz M, Ackermann M, Emmrich F, Loeffler M, Kamprad M. Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastin schedules in a chemotherapy mouse model. Biologics 3 (2009), S. 27-37.
  • Scholz M, Kamprad M, Ackermann M, Löffler M, Emmrich F, Engel Ch. A Pharmacokinetic Model of Filgrastim and Pegfilgrastim application in Normal and Cyclophosphamide Induced Granulopenic Mice. Cell Proliferat 42 (2009), 6, S. 813-22.
  • Simon P, Burkhardt U, Sack U, Kaisers UX, Muensterer OJ. Inflammatory Response Is No Different in Children Randomized to Laparoscopic or Open Appendectomy. J Laparoendosc Adv A, 19 (2009), Suppl 1, S. S71-S76.
  • Sommer G, Kralisch S, Stangl V, Vietzke A, Köhler U, Stepan H, Faber R, Schubert A, Lössner U, Bluher M, Stumvoll M, Fasshauer M. Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells. J Cell Biochem, 106 (2009), 4, S. 729-37.
  • Stadler PF, Chen JJ, Hackermüller J, Hoffmann S, Horn F, Khaitovich P, Kretzschmar AK, Mosig A, Prohaska SJ, Qi X, Schutt K, Ullmann K. Evolution of vault RNAs. Mol Biol Evol, 26 (2009), 9, S. 1975-91.
  • Stroh A, Boltze J, Sieland K, Hild K, Gutzeit C, Jung T, Kressel J, Hau S, Reich D, Grune T, Zimmer C. Impact of magnetic labeling on human and mouse stem cells and their long-term magnetic resonance tracking in a rat model of Parkinson disease. Mol Imaging, 8 (2009), 3, S. 166-78.
  • Tessema B, Muche A, Bekele A, Reissig D, Emmrich F, Sack U. Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia. A five - year retrospective study. BMC Public Health, 4 (2009), 371.
  • Wechsler L, Steindler D, Borlongan C, Chopp M, Savitz S, Deans R, Caplan L, Hess D, Mays RW, Boltze J, Boncoraglio G, Borlongan CV, Caplan LR, Carmichael ST, Chopp M, Davidoff AW, Deans RJ, Fisher M, Hess DC, Kondziolka D, Mays RW, Norrving B, Parati E, Parent J, Reynolds BA, Gonzalez-Rothi LJ, Savitz S, Sanberg P, Schneider D, Sinden JD, Snyder E, Steinberg GK, Steindler D, Wechsler L, Weiss MD, Weiss S, Victor S, Zheng T. Stem Cell Therapies as an Emerging Paradigm in Stroke Participants. Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke. Stroke, 40 (2009), 2, S. 510-5.
  • Wilcke A, Weissfuss J, Kirsten H, Wolfram G, Boltze J,Ahnert P. The role of gene DCDC2 in German dyslexics. Ann Dyslexia, 59 (2009), 1, S. 1-11.
  • Yerebakan C, Klopsch C, Prietz S, Boltze J, Vollmar B, Liebold A, Steinhoff G, Sandica E. Pressure-volume loops: feasible for the evaluation of right ventricular function in an experimental model of acute pulmonary regurgitation? Interact Cardiovasc Thorac Surg, 9 (2009), 2, S. 163-8.
  • Yerebakan C, Sandica E, Prietz S, Klopsch C, Ugurlucan M, Kaminski A, Abdija S, Lorenzen B, Boltze J, Nitzsche B, Egger D, Barten M, Furlani D, Ma N, Vollmar B, Liebold A, Steinhoff G. Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload. Cell Transplant, 18 (2009), 8, S. 855-68.

Publications 2008

  • Amemiya CT, Prohaska SJ, Hill-Force A, Cook A, Wasserscheid J, Ferrier DEK, Pascual-Anaya J, Garcia-Fernandez J, Dewar K, Stadler PF. The amphioxus Hox cluster: Characterization, comparative genomics, and evolution. J Exp Zool Part B 310B (2008), 5, S. 465-477.
  • Aupperle H, März I, Schubert A, Dinges G, Thielebein J, Schoon HA. Störungen des Metabolismus der extrazellularmatrix des Herzens bei der kaninen idiopathischen dilatativen Kardiomyopathie. Der praktische Tierarzt 89 (2008), 12, S. 998-1005.
  • Bernhart SH, Hofacker IL, Will S, Gruber AR, Stadler PF. RNAalifold. Improved consensus structure prediction for RNA alignments. BMC Bioinformatics. Online journal 9 (2008), Art. 474, 13S.
  • Bockamp E, Sprengel R, Eshkind L, Lehmann T, Braun JM, Emmrich F, Hengstler JG. Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration. Regen Med 3 (2008), 2, S. 217-35.
  • Bold A, Wurth R, Keller T, Trahorsch T, Voigt P, Schubert S, Sack U. Low-cost enumeration of CD4+ T cells using a density-based negative selection method (RosettaSepTM) for the monitoring of HIV-infected individuals in non-OECD countries. Cytom Part A 73 (2008), 1, S. 28-35.
  • Boltze J, Förschler A, Nitzsche B, Waldmin D, Hoffmann A, Boltze CM, Oreyer AY, Goldammer A, Reischauer A, Härtig W, Geiger KD, Barthel H, Emmrich F, Gille U. Permanent middle cerebral artery occlusion in sheep: a novel large animal model of focal cerebral ischemia. J Cerebr Blood F Met 28 (2008), 12, 1951-64.
  • Cepok S, Hoffmann S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wasmuth R, Hemmer B. HLA-DRB1 0401 and HLA-DRB1 0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis. J Neuroimmunol 203 (2008), 2, S. 194.
  • Daegelmann C, Herberth G, Röder S, Herbarth O, Giese T, Krämer U, Behrendt H, Borte M, Heinrich J, Emmrich F, Lehmann I; LISAplus study group. Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children. Clin Exp Allergy 38 (2008), 3, S. 438-48.
  • Davis LA, zur Nieden NI. Mesodermal fate decisions of a stem cell: the Wnt switch. Cell Mol Life Sci 65 (2008), 17, S. 2658-2674.
  • Dress AWM, Flamm C, Fritzsch G, Grünewald S, Kruspe M, Prohaska SJ, Stadler PF. Noisy: Identification of problematic columns in multiple sequence alignments. Algorithm Mol Biol. Online journal 3 (2008), Art. 7, 10S.
  • Focke A, Schwarz S, Foerschler A, Scheibe J, Milosevic J, Zimmer C, Schwarz J. Labeling of human neural precursor cells using ferromagnetic nanoparticles. Magn Reson Med. 2008 Dec;60(6):1321-8.

  • Geis M, Flamm C, Wolfinger MT, Tanzer A, Hofacker IL, Middendorf M, Mandl C, Stadler PF, Thurner C. Folding kinetics of large RNAs. J Mol Biol 379 (2008), 1, S. 160-173.
  • Gessner C, Dihazi H, Brettschneider S, Hammerschmidt S, Kuhn H, Eschrich K, Keller T, Engelmann L, Sack U, Wirtz H. Presence of cytokeratins in exhaled breath condensate of mechanical ventilated patients. Resp Med 102 (2008), 2, S. 299-306.
  • Goettsch W, Schubert A, Morawietz H. Expression of human endothelinconverting enzyme isoforms: role of angiotensin II. Can J Physiol Pharm 86 (2008), 6, S. 299-309.
  • Gruber AR, Kilgus C, Mosig A, Hofacker IL, Hennig W, Stadler PF. Arthropod 7SK RNA. Mol Biol Evol 25 (2008), 9, S. 1923-1930.
  • Hau S, Reich DM, Scholz M, Naumann W, Emmrich F, Kamprad M, Boltze, J. Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro. BMC Neurosci (2008), 9, S. 30.
  • Haussig S, Schubert A, Mohr FW, Dhein S. Sub-chronic nicotine exposure induces intercellular communication failure and differential down-regulation of connexins in cultured human endothelial cells. Atherosclerosis 196 (2008), 1, S. 210-8.
  • Hemdan NY. The role of interleukin-12 in the heavy metal-elicited immunomodulation: relevance of various evaluation methods. J Occup Med Toxicol 3 (2008), Art 25, 14S.
  • Hertel J, Hofacker IL, Stadler PF. SnoReport: Computational identification of snoRNAs with unknown targets. Bioinformatics 24 (2008), 2, S. 158-164.
  • Hoffmann S, Cepok S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wassmuth R, Hemmer B. HLA-DRB1*0401 and HLADRB1* 0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis. Am J Hum Genet 83 (2008), 2, S. 219-27.
  • Hollenbach M, Hintersdorf A, Huse K, Sack U, Bigl M, Groth M, Santel T, Buchold M, Lindner I, Otto A, Sicker D, Schellenberger D, Almendinger J, Pustowoit B, Birkemeyer C, Platzer M, Oerlecke I, Hemdan NY, Birkenmeier G. Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors. Biochem Pharmacol 76 (2008), 5, S. 631-644.
  • Hoppe A, Kamprad M, Wegmann C, Wötzel M, Hauss J, Emmrich F, Fangmann J, Sack U. Natürliche Killerzellen und natürliche Killer-T-Zellen bei Nierentransplanta­tion. Laboratoriumsmedizin 32 (2008), 3, S. 140-147.
  • Jochl C, Rederstorff M, Hertel J, Stadler PF, Hofacker IL, Schrettl M, Haas H, Hüttenhofer A. Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis. Nucleic Acids Res 36 (2008), 8, S. 2677-2689.
  • Jung C, Stöckle C, Wiesmüller KH, Laub R, Emmrich F, Jung G, Melms A. Complementary strategies to elucidate T helper cell epitopes in myasthenia gravis. J Neuroimmunol 201/202 (2008), S. 41-49.
  • Kendziorra K, Barthel H, Erbs S, Emmrich F, Hambrecht R, Schuler G, Sabri O, Kluge R. Effect of Progenitor Cells on Myocardial Perfusion and Metabolism in Patients After Recanalization of a Chronically Occluded Coronary Artery. J Nucl Med 48 (2008), 4, S. 557-563.
  • Kirsten H, Blume M, Emmrich F, Hunzelmann N, Mierau R, Rzepka R, Vaith P, Witte T, Melchers I, Ahnert P. No association between Systemic Sclerosis and the C77G Polymorphism in the Human PTPRC (CD45) Gene. J Rheumatol 35 (2008), 9, S. 1817-1819.
  • Klemm K, Flamm C, Stadler PF. Funnels in energy landscapes. Eur Phys J B 63 (2008), 3, S. 387-391.
  • Kralisch S, Sommer G, Stangl V, Köhler U, Kratzsch J, Stepan H, Faber R, Schubert A, Lössner U, Vietzke A, Bluher M, Stumvoll M, Fasshauer M. Secretory products from human adipocytes impair endothelial function via nuclear factor kappaB. Atherosclerosis 196 (2008), 2, S. 523-31.
  • Krauss V, Thummler C, Georgi F, Lehmann J, Stadler PF, Eisenhardt C. Near intron positions are reliable phylogenetic markers: An application to holometabolous insects. Mol Biol Evol 25 (2008), 5, S. 821-830.
  • Krupp W, Holland H, Koschny R, Bauer M, Schober R, Kirsten H, Livrea M, Meixensberger J, Ahnert P. Genome-wide genetic characterization of an atypical meningioma by single-nucleotide polymorphism array-based mapping and classical cytogenetics. Cancer Genet Cytogenet. 2008 Jul 15;184(2):87-93.
  • Kyaw WO, Uhlig A, Koller G, Sack U, Schusser GF. Freies Hämoglobin und Tumor-Nekrose-Faktor-Alpha im Blut von Pferden mit Kolik oder akuter Kolitis. Berl Munch Tierarztl W 121 (2008), 11-12, S. 440-445.
  • Lehmann J, Stadler PF, Prohaska SJ. SynBlast: Assisting the analysis of conserved synteny information. BMC Bioinformatics. Online journal 9 (2008), Art. 351, 14S.
  • Marz M, Kirsten T, Stadler PF. Evolution of spliceosomal snRNA genes in metazoan animals. J Mol Evol 67 (2008), 6, S. 594-607.
  • Morgenstern V, Zutavern A, Cyrys J, Brockow I, Koletzko S, Krämer U, Behrendt H, Herbarth O, von Berg A, Bauer CP, Wichmann HE, Heinrich J; GINI Study Group; LISA Study Group. Atopic diseases, allergic sensitization, and exposure to trafficrelated air pollution in children. Am J Resp Crit Care M 177 (2008), 12, S. 1331-1337.
  • Perseke M, Fritzsch G, Ramsch K, Bernt M, Merkle D, Middendorf M, Bernhard D, Stadler PF, Schlegel M. Evolution of mitochondrial gene orders in echinoderms. Mol Phylogenet Evol 47 (2008), 2, S. 855-864.
  • Pfefferkorn P, Scholz U, Veneruso V, Nikolaus T, Madin K, Eichenlaub U, Schubert A, Lehmann J. Influence of Serum Deprivation on Adherence and Proliferation of Murine Mesenchymal Progenitor Cells Analysed with Roche´s xCELLigence System. Biochemica (2008), 4, S. 14-16.
  • Pierzchalski A, Robitzki A, Mittag A, Emmrich F, Sack U, O‘Connor JE, Bocsi J, Tarnok A. Cytomics and nanobioengineering. Cytom Part B-Clin Cy 74 (2008), 6, S. 416-426.
  • Reich DM, Hau S, Stahl T, Scholz M, Naumann W, Emmrich F, Boltze J, Kamprad M. Neuronal hypoxia in vitro: investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells. BMC Neurosci (2008), 9, S. 91.
  • Rose D, Hertel J, Reiche K, Stadler PF, Hackermüller J. NcDNAlign: plausible multiple alignments of non-proteincoding genomic sequences. Genomics 92 (2008), 1, S. 65-74.
  • Rose D, Jöris J, Hackermüller J, Reiche K, Li Q, Stadler PF. Duplicated RNA genes in teleost fish genomes. J Bioinform Comput Biol 6 (2008), 6, 1157-75.
  • Sack U, Emmrich F. Monoklonale Antikörper: Prinzipien, Herstellung, Anwendung und Nebenwirkungen. Internist 49 (2008), 8, S. 921-928.
  • Santel T, Pflug G, Hemdan NY, Schafer A, Hollenbach M, Buchold M, Hintersdorf A, Lindner I, Otto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebhardt R, Platzer M, Weiss T, Vijayalakshmi MA, Kruger M, Birkenmeier G. Curcumin inhibits glyoxalase 1: a possible link to its antiinflammatory and anti-tumor activity. PLoS ONE (2008), 3, S. e3508.
  • Schimmelpfennig C. Biolumineszenz- und Fluoreszenz-Imaging: Ein neues Verfahren zur nicht-invasiven Bildgebung von zellbiologischen Prozessen in Kleintieren. Ingenieur Nachrichten (2008), 2, S. 10.
  • Schimmelpfennig C, Schmiedeknecht A, Emmrich F. Visualisierung von Immunfunktionen mithilfe von Biolumineszenz Imaging. Biospektrum 14 (2008), 5, S. 481-482.
  • Schoefer Y, Zutavern A, Brockow I, Schäfer T, Krämer U, Schaaf B, Herbarth O, von Berg A, Wichmann HE, Heinrich J; LISA study group. Health risks of early swimming pool attendance. Int J Hyg Envir Heal 211 (2008), 3-4, S. 367-73.
  • Schulz SM, Köhler G, Schütze N, Knauer J, Straubinger RK, Chackerian AA, Witte E, Wolk K, Sabat R, Iwakura Y, Hölscher C, Müller U, Kastelein RA, Alber G. Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is asso ciated with IL-23-dependent IL-22, but not IL-17. J Immunol 181 (2008), 11, S. 7891-901.
  • Sonnleitner E, Sorger-Domenigg T, Madej MJ, Findeiss S, Hackermüller J, Hüttenhofer A, Stadler PF, Bläsi U, Moll I. Detection of small RNAs in Pseudomonas aeruginosa by RNomics and structure-based bioinformatic tools. Microbiology 154 (2008), 10, S. 3175-87.
  • Stolzing A, Jones E, McGonagle D, Scutt A. Age related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies. Mech Ageing Dev, 129 (2008), 3, S. 163-173.
  • Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, Lehmann J, Sack U. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytom Part A 73 (2008), 3, S. 351-360.
  • Trepnau D, Ulrich E, Uhlig R, Lindner T, Selbitz HJ, Rösler U, Gabert J, Bergfeld U, Fehlhaber K, Brabetz W, Lehmann J. Antikörperantwort nach Impfung von Mastschweinen mit einem Salmonella-Typhimurium-Lebendimpfstoff in Abhängigkeit von der Applikationsform. Berl Munch Tierarztl 121 (2008), 9-10, S. 334-340.
  • Ueberham E, Lindner R, Kamprad M, Hiemann R, Hilger N, Woithe B, Mahn D, Cross M, Sack U, Gebhardt R, Arendt T, Ueberham U. Oval cell proliferation in p16INK4a expressing mouse liver is triggered by chronic growth stimuli. J Cell Mol Med 12 (2008), 2, S. 622-638.
  • Weimann A, Eisele RM, Pawellek S, Hippler-Benscheid M, Rüggeberg A, Cammann H, Radke C, Müller C, Klupp J, Sack U, Lun A. Diagnostic value of peripheral blood markers for acute rejection in LTX-patients receiving anti IL-2R antibodies. Laboratoriumsmedizin 32 (2008), 3, S. 148-157.
  • Willms H, Wiechmann V, Sack U, Gillissen A. Tracheobronchopathia osteochondroplastica: A rare cause of chronic cough with haemoptysis. Cough 4 (2008), 4, 4S.
  • Zutavern A, Brockow I, Schaaf B, von Berg A, Diez U, Borte M, Kraemer U, Herbarth O, Behrendt H, Wichmann HE, Heinrich J; LISA Study Group. Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA. Pediatrics (2008), 121, S. e44-52.

Publications 2007

  • Ahnert P, Kirsten H. Association of ITGAV supports a role of angiogenesis in rheumatoid arthritis. Arthritis Res Ther. 2007;9(5):108.
  • Athanasius F, Bompfünewerer Consortium, Backofen R, Bernhart SH, Flamm C, Fried C, Fritzsch G, Hackermüller J, Hertel J, Hofacker IL, Missal K, Mosig A, Prohaska SJ, Rose D, Stadler PF, Tanzer A, Washietl S, Will S. RNAs everywhere: genome-wide annotation of structured RNAs. J Exp Zool Part B (2007), 308, S. 1-25.
  • Aupperle H, Garbade J, Schubert A, Barten M, Dhein S, Schoon HA, Mohr FW. Effects of autologous stem cells on immunohistochemical patterns and gene expression of metalloproteinases and their tissue inhibitors in doxorubicin cardiomyopathy in a rabbit model. Vet Pathol 44 (2007), 4, S. 494-503.
  • Averbeck M, Gebhardt C, Emmrich F, Treudler R, Simon JC. Immunologic principles of allergic disease. J Dtsch Dermatol Ges 5 (2007), 11, S. 1015-28.
  • Backofen R, Flamm C, Fried C, Fritzsch G, Hackermüller J, Hertel J, Hofacker IL, Missal K, Prohaska SJ, Mosig A, Rose D, Stadler PF, Tanzer A, Washietl S, Will S. RNAs everywhere: genome-wide annotation of structured RNAs. J Exp Zool Part B, 308B (2007), 1, S. 1-25.
  • Bernt M, Merkle D, Ramsch K, Fritzsch G, Perseke M, Bernhard D, Schlegel M, Stadler PF, Middendorf M. CREx: inferring genomic rearrangements based on common intervals. Bioinformatics 23 (2007), 21, S. 2957-2958.
  • Brulport M, Schormann W, Bauer A, Hermes M, Elsner C, Hammersen FJ, Beerheide W, Spitkovsky D, Hartig W, Nussler A, Horn LC, Edelmann J, Pelz-Ackermann O, Petersen J, Kamprad M, von Mach M, Lupp A, Zulewski H, Hengstler JG. Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers. Hepatology 46 (2007), 3, S. 861-870.
  • Brumme S, Arnold T, Sigmarsson H, Lehmann J, Scholz HC, Hardt WD, Hensel A, Truyen H, Roesler U. Impact of Salmonella Typhimurium DT104 Virulence Factors invC and sseD affecting the onset, clinical course, colonization patterns and immune response of porcine salmonellosis. Vet Microbiol, 124 (2007), 3-4, S. 274-285.
  • Emmrich, F. Regenerative Medicine Today. BioWorld EUROPE Special Edition 1 (2007), S. 2-4.
  • ENCODE Project Consortium. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007), 447, S. 799-816.
  • Fangmann J, Wegmann C, Hoppe A, Martin P, Sack U, Harms J, Faber S, Emmrich F. Characterization of dendritic cell subsets in patients undergoing renal transplantation. Transplant Proc 39 (2007), 10, S. 3101-3104.
  • Förschler A, Boltze J, Waldmin D, Gille U, Zimmer C. MRI of experimental focal cerebral ischemia in sheep. Rofo 179 (2007), 5, S. 516-24.
  • Gebauer CM, Lenk H, Friedrich W, Sack U, Schuster V. Severe clinical course of Wiskott-Aldrich-syndrome – clinical course, hematologic, immunologic and genetic findings. Kinder- und Jugendmedizin (2007), 7, S. 39-44.
  • Gessner C, Hammerschmidt S, Kuhn H, Hoheisel G, Gillissen A, Sack U, Wirtz H. Breath Condensate nitrite correlates with hyperinflation in chronic obstructive pulmonary disease. Resp Med 101 (2007), 11, S. 2271-2278.
  • Hackermüller J, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447 (2007), 7146, S. 799-816.
  • Hemdan NY, Emmrich F, Faber S, Lehmann J, Sack U. Alterations of Th1/Th2 reac tivity by heavy metals – Possible consequences include induction of autoimmune diseases. Ann NY Acad Sci (2007), 1109, S. 129-137.
  • Hemdan NY, Lehmann I, Wichmann G, Lehmann J, Emmrich F, Sack U. Immunomodulation by mercuric chloride in vitro: application of different cell activation pathways. Clin Exp Immunol 148 (2007), 2, S. 325-37.
  • Hiemann R, Hilger N, Michel J, Nitschke J, Bohm A, Anderer U, Weigert M, Sack U. Automatic analysis of immunofluorescence patterns of HEp-2 cells. Ann NY Acad Sci 1109 (2007), 1, S. 358-371.
  • Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Kirsten H, Ahnert P. Comprehensive cytogenetic characterization of an esthesioneuroblastoma. Cancer Genet Cytogenet. 2007 Mar;173(2):89-96.

  • Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Schober R, Kirsten H, Ganten TM, Ahnert P. Cytogenetic and molecular biological characterization of an adult medulloblastoma. Cancer Genet Cytogen 178 (2007), 2, S. 104-113.
  • Kaltenhäuser S, Pierer M, Arnold S, Kamprad M, Baerwald C, Hantzschel H, Wagner U. Anti-bodies against cyclic citrullinated peptide are associated with the DRB1 shared epitope and predict joint erosion in rheumatoid arthritis. Rheumatology 46 (2007), 1, S. 100-104.
  • Kamprad M, Kindler S, Schuetze N, Emmrich F. Flow cytometric immunophenotyping of umbilical cord and peripheral blood haematopoietic progenitor cells by different CD34 epitopes, CD133, P-glycoprotein expression and rhodamine-123 efflux. Transfus Med  Hemoth 34 (2007), 3, S. 195-203.
  • Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, Stadler PF, Hertel J, Hackermüller J, Hofacker IL, Bell I, Cheung E, Drenkow J, Dumais E, Patel S, Helt G, Ganesh M, Ghosh S, Piccolboni A, Sementchenko V, Tammana H, Gingeras TR. RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science  316 (2007), 5830, S. 1484-1488.
  • Kirsten H, Teupser D, Weissfuss J, Wolfram G, Emmrich F, Ahnert P. Robustness of single-base extension against mismatches at the site of primer attachment in a clinical assay. J Mol Med 85 (2007), 4, S. 361-9.
  • Kruspe M, Stadler PF. Progressive multiple sequence alignments from triplets. BMC Bioinformatics. Online journal 8 (2007), S. 254.
  • Löffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermüller J, Kretzschmar AK, Burger R, Gramatzki M, Blumert C, Bauer K, Cvijic H, Ullmann AK, Stadler PF, Horn F. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110 (2007), 4, S. 1330-3.
  • Meng GL, zur Nieden NI, Liu SY, Cormier JT, Kallos MS, Rancourt DE. Properties of murine embryonic stem cells maintained on human foreskin fibroblasts without LIF. Mol Reprod Dev, 75 (2007), 4, S. 614-622.
  • Mosig A, Guofeng M, Stadler BMR, Stadler PF. Evolution of the vertebrate Y RNA cluster. Theor Biosci 126 (2007), 1, S. 9-14.
  • Rose D, Hackermüller J, Washietl S, Reiche K, Hertel J, Findeiß S, Stadler PF, Prohaska SJ. Computational RNomics of drosophilids. BMC Genomics. Online journal 8 (2007), Art. 406.
  • Saalbach A, Klein C, Sleeman J, Sack U, Kauer F, Gebhardt C, Averbeck M, Anderegg U, Simon JC. Dermal fibroblasts induce maturation of dendritic cells. J Immunol 178 (2007), 8, S. 4966-4974.
  • Sack U, Bocsi J, Tarnok A. Importance of cytometry for clinical diagnostics and therapy. Transfus Med Hemoth 34 (2007), 3, S. 153-154.
  • Sack U, Conrad K, Csernok E, Frank I, Haass M, Krieger T, Seyfarth M, Schlosser U, Schmidt R, Witte T. Standardization of autoimmune diagnostics in Germany: activities of the German group in the European Autoimmune Standardization Initiative. Ann NY Acad Sci (2007), 1109, S. 31-36.
  • Sack U, Gerling F, Tarnok A. Age-related lymphocyte subset changes in the peripheral blood of healthy children – A metastudy. Transfus Med Hemoth 34 (2007), 3, S. 176-181.
  • Savkovic V, Gantzer H, Reiser U, Selig L, Gaiser S, Sack U, Kloppel G, Mossner J, Keim V, Horn F, Bodeker H. Clusterin is protective in pancreatitis through anti-apoptotic and anti-inflammatory properties. Biochem Bioph Res Co 356 (2007), 2, S. 431-437.
  • Schloendorn J, Sethe S, Stolzing A. Cellular therapy using microglial cells. Rejuv Res 10 (2007), 1, S. 87-99.
  • Schmidt A, Haas SJ, Hildebrandt S, Scheibe J, Eckhoff B, Racek T, Kempermann G, Wree A, Pützer BM. Selective targeting of adenoviral vectors to neural precursor cells in the hippocampus of adult mice: new prospects for in situ gene therapy. Stem Cells. 2007 Nov;25(11):2910-8. Epub 2007 Jul 19.

  • Schwenk M, Sack U, Esser C, Klein R. Diagnostic relevance of the determination of lymphocyte subpopulations in environmental medicine. Int J Hyg Envir Heal 210 (2007), 2, S. 177-198.
  • Schwamborn JC, Müller M, Becker AH, Püschel AW. Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. EMBO J. 2007 Mar 7;26(5):1410-22. Epub 2007 Feb 22.
  • Sharma N, Kaur J, Xhu H, zur Nieden NI, Rancourt DE. Characterization of secretory leukocyte protease inhibitor (SLPI) as an inhibitor of implantation serine proteinase. Mol Reprod Dev, 75 (2007), 7, S. 1136-1142.
  • Stolzing A, Hescheler J, Sethe S. Fusion and regenerative therapies: is immortality really recessive? Rejuv Res 10 (2007), 4, S. 571-86.
  • Tanneberger K, Kirchberger J, Bar J, Schellenberger W, Rothemund S, Kamprad M, Otto H, Schoneberg T, Edelmann A. A novel form of 6-phosphofructokinase – Identification and functional relevance of a third type of subunit in pichia pastoris. J Biol Chem 282 (2007), 32, S. 23687-23697.
  • Washietl S, Pedersen JS, Korbel JO, Stocsits C, Gruber AR, Hackermüller J, Hertel J, Lindemeyer M, Reiche K, Tanzer A, Ucla C, Wyss C, Antonarakis SE, Denoeud F, Lagarde J, Drenkow J, Kapranov P, Gingeras TR, Guigó R, Snyder M, Gerstein MB, Reymond A, Hofacker IL, Stadler PF. Structured RNAs in the ENCODE selected regions of the human genome. Genome Res 17 (2007), 6, S. 852-64.
  • zur Nieden NI, Cormier JT, Rancourt DE, Kallos MS. Embryonic stem cells remain highly pluripotent following long term expansion as aggregates in suspension bioreactors. J Biotechnol 129 (2007), 3, S. 421-432.
  • zur Nieden NI, Price FD, Davis LA, Everitt R, Rancourt DE. Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for beta-catenin in osteogenic differentiation. Mol Endocrinol 21 (2007), 3, S. 674-685.

Publications 2006

  • Baumann JG. Intracellular restriction factors in mammalian cells – an ancient defense system finds a modern foe. Curr HIV Res, 4 (2006), 2, S. 141-168.
  • Birkenmeier G, Nicklisch S, Pockelt C, Mossie A, Steger V, Glaser C, Hauschildt S, Usbeck E, Huse K, Sack U, Bauer M, Schafer A. Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: modes of action and impact on lethality. J Pharmacol Exp Ther, 318 (2006), 2, S. 762-771.
  • Bocsi J, Lenz D, Mittag A, Varga VS, Molnar B, Tulassay Z, Sack U, Tarnok A. Automated four-color analysis of leukocytes by scanning fluorescence microscopy using quantum dots. Cytom Part A, 69 (2006), 3, S. 131-134.
  • Bocsi J, Mittag A, Sack U, Gerstner AO, Barten MJ, Tarnok A. Novel aspects of systems biology and clinical cytomics. Cytom Part A, 69 (2006), 3, S. 105-108.
  • Boltze J, Kowalski I, Forschler A, Schmidt U, Wagner D, Lobsien D, Emmrich J, Egger D, Kamprad M, Blunk J, Emmrich F. The stairway: a novel behavioral test detecting sensomotoric stroke deficits in rats. Artif Organs, 30 (2006), 10, S. 756-763.
  • Brocke-Heidrich K, Ge B, Cvijic H, Pfeifer G, Loffler D, Henze C, McKeithan TW, Horn F. BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription. Oncogene, 25 (2006), 55, S. 7297-7304.
  • Colsman A, Sticherling M, Stopel C, Emmrich F. Computer-assisted learning in medicine : how to create a novel software for immunology. Arch Dermatol Res, 298 (2006), 1, S. 1-6.
  • Cormier JT, zur Nieden NI, Rancourt DE, Kallos MS. Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors. Tissue Eng, 12 (2006), 11, S. 3233-3245.
  • Dietrich A, Stockmar C, Aust G, Endesfelder S, Guetz A, Sack U, Schoenfelder M, Hauss J. Intraoperative subcutaneous or intrasplenic vaccination with modified autologous tumor cells leads to enhanced survival in a mouse tumor model. J Cancer Res Clin, 132 (2006), 6, S. 379-388.
  • Ehlers J, Alt M, Trepnau D, Lehmann J. Anwendung neuer Immunglobulin-isotypspezifischer ELISA-Systeme zur Erkennung von Salmonelleninfektionen bei Schweinen. Berl Munch Tierarztl 119 (2006), 11-12, S. 461-466.
  • Emmrich F. Regenerative Medizin – Made in Germany. Zeitschrift für Regenerative Medizin, 1. Jahrg. (2006), 1.
  • Funke B, Jungel A, Schastak S, Wiedemeyer K, Emmrich F, Sack U. Transdermal photodynamic therapy-a treatment option for rheumatic destruction of small joints? Laser Surg Med, 38 (2006), 9, S. 866-874.
  • Giese M, Liebert UG, Schneider T, Bock K, Zahn N, Uhlig A, Schusser GF. Therapeutical immunization of EAV-infected horses by DNA-Vaccination. Reprod Domest Anim 41 (2006), 4, S. 297-298.
  • Härtig W, Lehmann J, Stieler J, Singer D, Grosche J, Arendt T, Hoffmann R. Simultaneous detection of tau phospho-epitopes with haptenylated antibodies. Neuroreport, 17 (2006), 9, S. 869-875.
  • Hemdan NY, Emmrich F, Sack U, Wichmann G, Lehmann J, Adham K, Lehmann I. The in vitro immune modulation by cadmium depends on the way of cell activation. Toxicology 222 (2006), 1-2, S. 37-45.
  • Hiemann R, Hilger N, Sack U, Weigert M. Objective quality evaluation of fluorescence images to optimize automatic image acquisition. Cytom Part A, 69 (2006), 3, S. 182-184.
  • Kirsten H, Dienst S, Emmrich F, Ahnert P. CalcDalton: a tool for multiplex genotyping primer design for single-base extension reactions using cleavable primers. Biotechniques, 40 (2006), 2, S. 158-160.
  • Koschny R, Holland H, Koschny T, Vitzthum HE. Comparative genomic hybridization pattern of non-anaplastic and anaplastic oligodendrogliomas – a meta-analysis. Pathol Res Pract, 202 (2006), 1, S. 23-30.
  • Lange F, Hartl S, Ungethuem U, Kuban RJ, Hammerschmidt S, Faber S, Morawietz L, Wirtz H, Emmrich F, Krenn V, Sack U. Anti-TNF effects on destructive fibroblasts depend on mechanical stress. Scand J Immunol, 64 (2006), 5, S. 544-553.
  • Lehmann J, Springer S, Werner CE, Lindner T, Bellmann S, Straubinger RK, Selbitz HJ, Alber G. Immunity induced with a Salmonella enterica serovar enteritidis live vaccine is regulated by Th1-cell-dependent cellular and humoral effector mechanisms in susceptible BALB/c mice. Vaccine, 24 (2006), 22, S. 4779-4793.
  • Mishto M, Bellavista E, Santoro A, Stolzing A, Ligorio C, Nacmias B, Spazzafumo L, Chiapelli M, Licastro F, Sorbi S, Pession A, Ohm T, Grune T, Franceschi C. Immunoproteasome and LMP2 polymorphism in aged and Alzheimer’s disease brains. Neurobiol Aging, 27 (2006), 1, S. 54-66.
  • Mittag A, Lenz D, Bocsi J, Sack U, Gerstner AO, Tarnok A. Sequential photobleaching of fluorochromes for polychromatic slide-based cytometry. Cytom Part A, 69 (2006), 3, S. 139-141.
  • Morawietz H, Erbs S, Holtz J, Schubert A, Krekler M, Goettsch W, Kuss O, Adams V, Lenk K, Mohr FW, Schuler G, Hambrecht R. Endothelial protection, AT1 blockade and cholesterol-dependent oxidative stress: the EPAS trial. Circulation, 114 (2006), 1, S. 1296-1301.
  • Mückstein U, Tafer H, Hackermüller J, Bernhart SH, Stadler PF, Hofacker IL. Thermodynamics of RNA-RNA binding. Bioinformatics 22 (2006), 10, S. 1177-1182.
  • Müller H, Johne R, Schusser G, Giese M, Linke S, Pauli G. West Nile Virus - Causative agent of a zoonosis with increasing significance? Deut Tierarztl Woch 113 (2006), 12, S. 435-439.
  • Pohl S, Fricke S, Hildebrandt G, Uharek L, Braun JM, Emmrich F. Permanent induction of specific immunotolerance to allograft and prevention of graft-versushost-disease. Zeitschrift für Regenerative Medizin (2006), 1, S. 60.
  • Poppek D, Keck S, Ermack G, Jung T, Stolzing A, Ullrich O, Davies KJ, Grune T. Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress. Biochem J 400 (2006), 3, S. 511-520.
  • Rulli SJjr, Muriaux D, Nagashima K, Mirro J, Oshima M, Baumann JG, Rein A. Mutant murine leukemia virus Gag proteins lacking proline at the N-terminus of the capsid domain block infectivity in virions containing wild-type Gag. Virology, 347 (2006), 2, S. 364-371.
  • Sack U, Biereder B, Elouahidi T, Bauer K, Keller T, Trobs RB. Diagnostic value of blood inflammatory markers for detection of acute appendicitis in children. BMC Surg 6 (2006), 15.
  • Sack U, Scheibe R, Wötzel M, Hammerschmidt S, Kuhn H, Emmrich F, Hoheisel G, Wirtz H, Gessner C. Multiplex analysis of cytokines in exhaled breath condensate. Cytom Part A, 69 (2006), 3, S. 169-172.
  • Seleverstov O, Zabirnyk O, Zscharnack M, Bulavina L, Nowicki M, Heinrich JM, Yezhelyev M, Emmrich F, O Regan R, Bader A. Quantum dots for human mesenchymal stem cells labeling. A size-dependent autophagy activation. Nano Lett, 6 (2006), 12, S. 2826-2832.
  • Selig L, Sack U, Gaiser S, Kloppel G, Savkovic V, Mossner J, Keim V, Bodeker H. Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen. BMC Gastroenterol (2006), 6, S. 30ff.
  • Sethe S, Scutt A, Stolzing A. Aging of mesenchymal stem cells. Aging Res Rev (2006), 5, S. 91-116.
  • Singer D, Lehmann J, Hanisch K, Härtig W, Hoffmann R. Neighbored phosphorylation sites as PHF-tau specific markers in Alzheimer’s disease. Biochem Bioph Res Co (2006), 346, S. 819-828.
  • Stolzing A, Scutt A. Age-related impairment of mesenchymal progenitor cell function. Aging Cell (2006), 5, S. 213-224.
  • Stolzing A, Scutt A. Effect of reduced culture temperature on antioxidant defences of mesenchymal stem cells. Free Radical Bio Med, 41 (2006), 2, S. 326-38.
  • Stolzing A, Scutt A. Glucose-induced replicative senescence in mesenchymal stem cells. Rejuv Res, 9 (2006), 1, S. 31-35.
  • Stolzing A, Sethe S, Scutt A. Stressed stem cells: temperature response in aged mesenchymal stem cells. Stem Cells Dev, 15 (2006), 4, S. 478-87.
  • Stolzing A, Widmer R, Jung T, Grune T. Tocopherol-mediated modulation of age-related changes in microglial cells: turnover of extracellular oxidized protein material. Free Radical Bio Med 40 (2006), 12, S. 2126-2135.
  • Stolzing A, Widmer R, Jung T, Voss P, Grune T. Degradation of glycated bovine serum albumin in microglial cells. Free Radical Bio Med, 40 (2006), 6, S. 1017-1027.
  • Walther T, Schubert A, Wustmann T, Falk V, Walther C, Doll N, Rastan A, Gummert J, Mohr FW. Reverse remodeling of cardiac collagen protein expression after surgical therapy for experimental aortic stenosis. J Heart Valve Dis, 15 (2006), 5, S. 651-6.

Publications 2005

  • Aust G, Kamprad M, Lamesch P, Schmücking E. CXCR6 within T-helper (Th) and T-cytotoxic (Tc) type 1 lymphocytes in Graves’ disease (GD). Eur J Endocrinol, 152 (2005), 4, S. 635-643.
  • Boltze J, Kowalski I, Geiger K, Reich D, Gunther A, Buhrle C, Egger D, Kamprad M, Emmrich F. Experimental treatment of stroke in spontaneously hypertensive rats by CD34+ and CD34-cord blood cells. Ger Med Sci, 3, Doc09 (2005), 20051110.
  • Burkhardt C, Müller M, Badde A, Garner CC, Gundelfinger ED, Püschel AW. Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif. FEBS Lett. 2005 Jul 4;579(17):3821-8.
  • Erbs S, Linke A, Adams V, Lenk K, Thiele H, Diederich KW, Emmrich F, Kluge R, Kendziorra K, Sabri O, Schuler G, Hambrecht R. Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study. Circ Res, 97 (2005), 8, S. 756-762.
  • Garbade J, Schubert A, Rastan AJ, Lenz D, Walther T, Gummert JF, Dhein S, Mohr FW. Fusion of bone marrow-derived stem cells with cardiomyocytes in a heterologous in vitro model. Eur J Cardio-Thorac, 28 (2005), 5, S. 685-91.
  • Gessner C, Scheibe R, Wötzel M, Hammerschmidt S, Kuhn H, Engelmann L, Hoheisel G, Sack U. Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease. Resp Med, 99 (2005), 10, S. 1229-1240.
  • Gielen S, Adams V, Linke A, Erbs S, Mobius-Winkler S, Schubert A, Schuler G, Hambrecht R. Exercise training in chronic heart failure: correlation between reduced local inflammation and improved oxidative capacity in the skeletal muscle. Eur J Cardiov Prev R,12 (2005), 4, S. 393-400.
  • Hambrecht R, Schulze PC, Gielen S, Linke A, Mobius-Winkler S, Erbs S, Kratzsch J, Schubert A, Adams V, Schuler G. Effects of exercise training on insulin-like growth factor-I expression in the skeletal muscle of non-cachectic patients with chronic heart failure. Eur J Cardiov Prev R,12 (2005), 4, S. 401-6.
  • Hammerschmidt S, Kuhn H, Sack U, Schlenska A, Gessner C, Gillissen A, Wirtz H. Mechanical stretch alters alveolar type II cell mediator release toward a proinflammatory pattern. Am J Resp Cell Mol, 33 (2005), 2, S. 203-210.
  • Hemdan NY, Emmrich F, Adham K, Wichmann G, Lehmann I, El-Massry A, Ghoneim H, Lehmann J, Sack U. Dose-dependent modulation of the in vitro cytokine production of human immune competent cells by lead salts. Toxicol Sci, 86 (2005), 1, S. 75-83.
  • Holtick U, Vockerodt M, Pinkert D, Schoof N, Sturzenhofecker B, Kussebi N, Lauber K, Wesselborg S, Löffler D, Horn F, Trümper L, Kube D. STAT3 is essential for Hodgkin lymphoma cell proliferation and is target of tyrphostin AG17 which confers sensitization for apoptosis. Leukemia, 19 (2005), 6, S. 936-944.
  • Lange F, Bajtner E, Caspar T, Rintisch C, Nandakumar KS, Sack U, Holmdahl R. Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis. Ann Rheum Dis, 64 (2005), 4, S. 599-605.
  • Lenk K, Adams V, Lurz P, Erbs S, Linke A, Gielen S, Schmidt A, Scheinert D, Biamino G, Emmrich F, Schuler G, Hambrecht R. Therapeutical potential of blood-derived progenitor cells in patients with peripheral arterial occlusive disease and critical limb ischaemia. Eur Heart J, 26 (2005), 18, S. 1903-1909.
  • Lenz D, Barten MJ, Hiller S, Tarnok A, Sack U. Regenerative and predictive medicine of cardiovascular disease: the 9th Leipziger Workshop and the 2nd International Workshop on slide based cytometry. Cytom Part A, 64 (2005), 2, S. 110-114.
  • Linke A, Adams V, Schulze PC, Erbs S, Gielen S, Fiehn E, Mobius-Winkler S, Schubert A, Schuler G, Hambrecht R. Antioxidative effects of exercise training in patients with chronic heart failure. Increase in radical scavenger enzyme activity in skeletal muscle. Circulation, 111 (2005), 14, S. 1763-70.
  • Mittag A, Lenz D, Gerstner AO, Sack U, Steinbrecher M, Koksch M, Raffael A, Bocsi J, Tarnok A. Polychromatic (eight-color) slide-based cytometry for the phenotyping of leukocyte, NK, and NKT subsets. Cytom Part A, 65 (2005), 2, S. 103-115.
  • Moche M, Hui DSC, Huse K, Chan KS, Choy DKL, Tannapfel A, Scholz GH, Gosse H, Sack U, Hoheisel G. Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion. Pneumologie, 59 (2005), 8, S. 523-528.
  • Pelz O, Wu M, Nikolova T, Kamprad M, Ackermann M, Egger D, Emmrich F, Wobus AM, Cross M. Duplex polymerase chain reaction quantification of human cells in a murine background. Stem Cells, 23 (2005), 6, S. 828-833.
  • Pohlers D, Siegling A, Buchner E, Schmidt-Weber CB, Palombo-Kinne E, Emmrich F, Brauer R, Kinne RW. Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis. Arthritis Res Ther, 7 (2005), 3, S. 445-457.
  • Rastan AJ, Walther T, Kostelka M, Garbade J, Schubert A, Stein A, Dhein S, Mohr FW. Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells-an in vitro-model. Eur J Cardio-Thorac, 27 (2005), 1, S. 104-10.
  • Sack U, Hirth A, Funke B, Wiedemeyer K, Lange F, Troltzsch M, Tannapfel A, Gebhardt R, Emmrich F, Lehmann J. A novel model of fibroblast-mediated cartilage destruction. Scand J Immunol, 61 (2005), 1, S. 18-28.
  • Sack U, Hoffmann M, Zhao XJ, Chan KS, Hui DS, Gosse H, Engelmann L, Schauer J, Emmrich F, Hoheisel G. Vascular endothelial growth factor in pleural effusions of different origin. Eur Respir J, 25 (2005), 4, S. 600-604.
  • Sack U, Sehm B, Kahlenberg F, Murr A, Lehmann J, Tannapfel A, Uberla K, Moessner A, Dietrich A, Emmrich F, Lange F, Jungel A, Braun JM, Anderegg U. Investigation of arthritic joint destruction by a novel fibroblastbased model. Ann NY Acad Sci 1051 (2005), 1, S. 291-298.
  • Schastak S, Jean B, Handzel R, Kostenich G, Hermann R, Sack U, Orenstein A, Wang YS, Wiedemann P. Improved pharmacokinetics, biodistribution and necrosis in vivo using a new near infra-red photosensitizer: tetrahydroporphyrin tetratosylat. J Photoch Photobio B, 78 (2005), 3, S. 203-213.
  • Schneider A, Sack U, Rothe K, Bennek J. Peritoneal taurolidine lavage in children with localised peritonitis due to appendicitis. Pediatr Surg Int 21 (2005), 6, S. 445-448.
  • Stolzing A, Sethe S, Grune T. Chronically active - role of oxidative stress in age and neuropathology. Redox Rep, 10 (2005), 4, S. 207-13.
  • Wötzel M, Schröder S, Sack U. Differentiation of anti-platelet antibodies using microspheres and flow cytometry. J Lab Clin Med (2005), 29, S. 368-376.
  • zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ. Induction of chondro-, osteoand adipogenesis in embryonic stem cells by bone morphogenetic protein-2: Effect of co-factors on differentiating lineages. BMC Dev Biol 5 (2005), 1, S. 1-15.