Proteinbiochemie

Publikationen

  • Bayly-Jones C, Lupton CJ, Fritz C, Venugopal H, Ramsbeck D, Wermann M, Jäger C, de Marco A, Schilling S, Schlenzig D, Whisstock JC. Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor. Nat Commun. 2022 Oct 19;13(1):6178. doi: 10.1038/s41467-022-33893-7
  • Linnert M, Fritz C, Jäger C, Schlenzig D, Ramsbeck D, Kleinschmidt M, Wermann M, Demuth H-U, Parthier C, Schilling S. Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor. Int. J. Mol. Sci. 2021, 22, doi: 10.3390/ijms22115651
  • Taudte N, Linnert M, Rahfeld J-U, Piechotta A, Ramsbeck D, Buchholz M, Kolenko P, Parthier C, Houston JA, Veillard F. Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis. J. Biol. Chem. 2021, 296, 100263, doi: 10.1016/j.jbc.2021.100263
  • Schulze A, Wermann M, Demuth HU, Yoshimoto T, Ramsbeck D, Schlenzig D, Schilling S. Continuous assays for meprin alpha and beta using prolyl tripeptidyl aminopeptidase (PtP) from Porphyromonas gingivalis. Anal Biochem. 2018 Oct 15;559:11-16. doi: 10.1016/j.ab.2018.08.005
  • Spahn C, Wermann M, Eichentopf R, Hause G, Schlenzig D, Schilling S. Purification of recombinant Aβ(1-42) and pGlu-Aβ(3-42) using preparative SDS-PAGE. Electrophoresis. 2017 Aug;38(16):2042-2049. doi: 10.1002/elps.201700154
  • Schlenzig D, Wermann M, Ramsbeck D, Moenke-Wedler T, Schilling S. Expression, purification and initial characterization of human meprin β from Pichia pastoris. Protein Expr Purif. 2015 Dec;116:75-81. doi: 10.1016/j.pep.2015.08.001