Fraunhofer-Institut für Zelltherapie und Immunologie IZI
Fraunhofer-Institut für Zelltherapie und Immunologie IZI

MicroDiagnostics

Publikationen und Patente

Publikationen

  • Allelein S, Aerchlimann K A, Roesch G, Khajehamiri R, Koelsch A, Freese C, Kuhlmeier D. Prostate-specific membrane antigen (PSMA)-positive extracellular vesicles in urine - a potential liquid biopsy strategy for prostate cancer diagnosis? Cancers (Basel). 2022 Jun 17;14(12):2987. doi: 10.3390/cancers14122987
  • Arbaciauskaite S, Babakhani P, Sandetskaya N, Vitkus D, Jancoriene L, Karosiene D, Karciauskaite D, Zablockiene B, Kuhlmeier D. Self-sampled gargle water direct RT-LAMP as a screening method for the detection of SARS-CoV-2 infections. Diagnostics (Basel). 2022 Mar 22;12(4):775. doi: 10.3390/diagnostics12040775
  • Biadglegne F, Schmidt J R, Engel K M, Lehmann J, Lehmann R T, Reinert A, Koenig B, Schiller J, Kalkhof S, Sack U. Mycobacterium tuberculosis affects protein and lipid content of circulating exosomes in infected patients depending on Tuberculosis disease state. Biomedicines. 2022 Mar 27;10(4):783. doi: 10.3390/biomedicines10040783
  • Allelein S, Medina-Perez P, Heitor Lopes AL, Rau S, Hause G, Kölsch A, Kuhlmeier D. Potential and challenges of specifically isolating extracellular vesicles from heterogeneous populations. Sci Rep. 2021 Jun 2;11(1):11585. dx.doi.org/10.1038/s41598-021-91129-y
  • Saha S, Allelein S, Pandey R, Medina-Perez P, Osman E, Kuhlmeier D, Soleymani L. Two-step competitive hybridization assay: a method for analyzing cancer-related microRNA embedded in extracellular vesicles. Anal Chem. 93 (2021), 48, Seite 15913-15921. doi: 10.1021/acs.analchem.1c03165
  • Steppert I, Schönfelder J, Schultz C, Kuhlmeier D. Rapid in vitro differentiation of bacteria by ion mobility spectrometry. Appl Microbiol Biotechnol. 2021 May;105(10):4297-4307. dx.doi.org/10.1007/s00253-021-11315-w. Epub 2021 May 11.
  • Derrick T, Sandetskaya N, Pickering H, Kölsch A, Ramadhani A, Mafuru E, Massae P, Malisa A, Mtuy T, Burton MJ, Holland MJ, Kuhlmeier D. DjinniChip: evaluation of a novel molecular rapid diagnostic device for the detection of Chlamydia trachomatis in trachoma-endemic areas. Parasites & vectors 13 (2020) Artikel-Nr.: 533, 10 Seiten. dx.doi.org/10.1186/s13071-020-04414-6
  • Sandetskaya N, Isserstedt-John N, Koelsch A, Schattschneider S, Kuhlmeier D. An integrated homogeneous SPARCL™ immunoassay for rapid biomarker detection on a chip. Analytical methods 11 (2019), 19, Seite 2542-2550, dx.doi.org/10.1039/c9ay00198k
  • Rüppel N, Tröger V, Sandetskaya N, Kuhlmeier D, Schmieder S, Sonntag F. Detection and identification of staphylococcus aureus using magnetic particle enhanced surface plasmon spectroscopy. Engineering in life sciences 18 (2018), 4, S. 263-268. dx.doi.org/10.1002/elsc.201700098
  • Sandetskaya N, Moos D, Seifert S, Jenerowicz M, Becker H, Zilch C, Kuhlmeier D. An integrated versatile lab-on-a-chip platform for the isolation and nucleic acid-based detection of pathogens. Future Science OA. 2017 May; 3(2). DOI:10.4155/fsoa-2016-0088
  • Gärtig C, Niemann K, Berthold J, Giel L, Leitschuh N, Boehm C, Roussak L, Vetter K, Kuhlmeier D. Development of a point-of-care-device for fast detection of periodontal pathogens. BMC Oral Health. 2015 Dec 24;15(1):165.
  • Tröger V, Niemann K, Gärtig C, Kuhlmeier D. Isothermal Amplification and Quantification of Nucleic Acids and its Use in Microsystems. Journal of Nanomedicine & Nanotechnology. 01/2015; 6(3). DOI dx.doi.org/10.4172/2157-7439.1000282
  • Sandetskaya N, Engelmann B, Brandenburg K, Kuhlmeier D. Application of immobilized synthetic anti-lipopolysaccharide peptides for the isolation and detection of bacteria. Eur J Clin Microbiol Infect Dis. 2015 May 19.
  • Sandetskaya N, Naumann A, Hennig K, Kuhlmeier D. Specific enrichment of prokaryotic DNA using a recombinant DNA-binding protein. Analytical and Bioanalytical Chemistry. 2014 Jun;406(15):3755-62. DOI dx.doi.org/10.1007/s00216-014-7787-7.
  • Sandetskaya N, Allelein S, Kuhlmeier D. Application of nanotechnology in miniaturized systems and its use for advanced analytics and diagnostics - an updated review. Recent Pat Food Nutr Agric. 2013 Dec;5(3):220-38.
  • Becker H, Carstens C, Kuhlmeier D, Sandetskaya N, Schröter N, Zilch C, Gärtner C. Stationary microfluidics: molecular diagnostic assays by moving magnetic beads through non-moving liquids. 20 Mar. 2013; SPIE Digital Library.
  • Sandetskaya N, Lorenzen M, Nachsel R, Pötter H, Kuhlmeier D, Carstens C, Gärtner C, Zilch C. Magnetpartikel-basiertes Mikrosystem zum magnetoresistiven Schnellnachweis Sepsis-relevanter Pathogene. Proceedings MikroSystemTechnik Kongress 2012, VDE-Verlag
  • Kuhlmeier D, Gärtig C. Mit der PCR der Parodontitis auf der Spur. BIOspektrum 02.13.
  • Kuhlmeier D, Sandetskaya N, Lorenzen M, Schotter J. Retter im Scheckkartenformat. Laborpraxis 03/2011.
  • Kuhlmeier D, Sandetskaya N, Allelein S. Application of nanotechnology in miniaturized systems and its use in medical and food analysis. Recent Pat Food Nutr Agric. 4 (2012), 3, S. 187-99. DOI dx.doi.org/10.2174/2212798411204030187.
  • Lindner I. et al. alpha 2-Macroglobulin Inhibits the Malignant Properties of Astrocytoma Cells by Impeding beta-Catenin Signaling. Cancer Research, v. 70 (2010), no. 1, p. 277-287.

 

Patente

  • Kuhlmeier D, Sandetskaya N, Hennig K, Naumann A. Methode zur spezifischen Isolation von Nukleinsäuren. Patent application PCT/EP2013/072331.