Department of Preclinical Development and Validation

Publications of the department

2023

  • Adamowicz K, Arend L, Maier A, Schmidt J R, Kuster B, Tsoy O, Zolotareva O, Baumbach J, Laske T. Proteomic meta-study harmonization, mechanotyping and drug repurposing candidate prediction with ProHarMeD. NPJ Syst Biol Appl 2023, 9(1): 49. doi: 10.1038/s41540-023-00311-7
  • Engel C, Wirkner K, Zeynalova S, Baber R, Binder H, Ceglarek U, Enzenbach C, Fuchs M, Hagendorff A, Henger S, Hinz A, Rauscher FG, Reusche M, Riedel-Heller SG, Röhr S, Sacher J, Sander C, Schroeter ML, Tarnok A, Treudler R, Villringer A, Wachter R, Witte AV, Thiery J, Scholz M, Loeffler M; LIFE-Adult-Study working group. Cohort Profile: The LIFE-adult-study. Int J Epidemiol 2023, 52 (1): E66 - E791. doi: 10.1093/ije/dyac114
  • Han Y, Zhao J, Chao Z, Liang K, Zhang C, Jiang L, Jiao Z, Bai F, Tarnok A, You Z. Imaging flow cytometry using linear array spot excitation. Device 2023, 1 (6): 100124. doi: 10.1016/j.device.2023.100124
  • Hoen L, Pfeffer D, Schmidt J R, Kraft J, Hildebrand J, Kalkhof S. Hydration status of geriatric patients is associated with changes in plasma proteome, especially in proteins involved in coagulation. Nutrients 2023, 15 (17), article 3789. doi: 10.3390/nu15173789
  • Kiefer N, Nichterlein M, Reiß F, Runge M, Biermann U, Wieland T, Noll M, Kalkhof S. Eluates from façades at the beginning of their service time affect aquatic and sediment organisms. Sci Total Environ 2023, 906, article 167531. doi: 10.1016/j.scitotenv.2023.167531
  • Schmidt J R, Haupt J, Riemschneider S, Kämpf C, Löffler D, Blumert C, Reiche K, Koehl U, Kalkhof S, Lehmann J. Transcriptomic signatures reveal a shift towards an anti-inflammatory gene expression profile but also the induction of type I and type II interferon signaling networks through aryl hydrocarbon receptor activation in murine macrophages. Front Immunol 2023, 14: article number 1156493. doi: 10.3389/fimmu.2023.1156493
  • Tanuchai B, Ji L, Schröder O, Gawol S J, Geissler A, Wahdan S F M, Buscot F, Kalkhof S, Schulze E-D, Noll M, Purahong W. Fate of a biodegradable plastic in forest soil: dominant tree species and forest types drive changes in microbial community assembly, influence the composition of plastisphere, and affect poly(butylene succinate-co-adipate) degradation. Sci Total Environ 2023, 873: article 162230. doi: 10.1016/j.scitotenv.2023.162230

2022

  • Biadglegne F, Schmidt JR, Engel KM, Lehmann J, Lehmann RT, Reinert A, König B, Schiller J, Kalkhof S, Sack U. Mycobacterium tuberculosis affects protein and lipid content of circulating exosomes in infected patients depending on tuberculosis disease state. Biomedicines. 2022 Mar 27;10(4):783. doi: 10.3390/biomedicines10040783. IF 6.081
  • Fueldner F, Riemschneider S, Haupt J, Jungnickel H, Schulze F, Zoldan K, Esser C, Hauschildt S, Knauer J, Luch A, Kalkhof S, Lehmann J. Aryl hydrocarbon receptor activation by benzo[a]pyrene prevents development of septic shock and fatal outcome in a mouse model of systemic Salmonella enterica infection. Cells. 2022 Feb 20;11(4):737. doi: 10.3390/cells11040737. IF 6.629
  • Furesi G, Jesus Domingues A M, Alexopoulou D, Dahl A, Hackl M, Schmidt J, Kalkhof S, Kurth T, Taipaleenmaeki H, Conrad S, Hofbauer C, Rauner M, Hofbauer L C. Exosomal miRNAs from prostate cancer impair osteoblast function in mice. Int J Mol Sci. 2022 Jan 24;23(3):1285. doi: 10.3390/ijms23031285 
  • Hoen L, Rudisch C, Wick M, Indenbirken M, Grundhoff A, Wegwitz F, Kalkhof S, Hildebrand J. Osmotic stress interferes with DNA damage response and H2AX phosphorylation in human keratinocytes. Cells. 2022 Mar 11;11(6):959. doi: 10.3390/cells11060959 
  • Jiao Z, Han Y, Zhao J, Chao Z, Tárnok A, You Z. Rapid switching and durable on-chip spark-cavitation-bubble cell sorter. Microsyst Nanoeng. 2022 May 18;8:52. doi: 10.1038/s41378-022-00382-2. eCollection 2022 
  • Nagel M, Moretti R, Paschke R, Bergen M, Meiler J, Kalkhof S. Integrative model of the FSH receptor reveals the structural role of the flexible hinge region. Structure. 2022 Oct 6;30(10):1424-1431.e3. doi: 10.1016/j.str.2022.07.007. Epub 2022 Aug 15 
  • Poh P S, Lingner T, Kalkhof S, Maerdian S, Baumbach J, Dondl P, Duda G N, Checa S. Enabling technologies towards personalization of scaffolds for large bone defect regeneration. Curr Opin Biotechnol. 2022 Apr;74:263-270. doi: 10.1016/j.copbio.2021.12.002. Epub 2022 Jan 7 
  • Schaffert A, Karkossa I, Ueberham E, Schlichting R, Walter K, Arnold J, Blüher M, Heiker J T, Lehmann J, Wabitsch M, Escher B I, Bergen M, Schubert K. Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes. Environ Int. 2022 Jun;164:107279. doi: 10.1016/j.envint.2022.107279. Epub 2022 May 6 
  • Semwala R, Semwal R B, Lehmann J, Semwal D K. Recent advances in immunotoxicity and its impact on human health: causative agents, effects and existing treatments. Int Immunopharmacol. 2022 Jul;108:108859. doi: 10.1016/j.intimp.2022.108859. Epub 2022 May 19 
  • Subirana M A, Riemschneider S, Hause G, Dobritzsch D, Schaumloeffel D, Herzberg M. High spatial resolution imaging of subcellular macro and trace element distribution during phagocytosis. Metallomics. 2022 Apr 1;14(4):mfac011. doi: 10.1093/mtomcs/mfac011
  • Werner M, Dyas A, Parfentev I, Schmidt G E, Mieczkowska I K, Mueller-Kirschbaum L C, Mueller C, Kalkhof S, Reinhardt O, Urlaub H, Alves F, Gallwas J, Prokakis E, Wegwitz F. ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness. Cell Death Dis. 2022 Sep 3;13(9):762. doi: 10.1038/s41419-022-05197-7

2021

  • Binder S, Zipfel I, Müller C, Wiedemann K, Schimmelpfennig C, Pfeifer G, Reiche K, Hauschildt S, Lehmann J, Köhl U, Horn F, Friedrich M. The noncoding RNA LINC00152 conveys contradicting effects in different glioblastoma cells. Sci Rep. 2021 Sep 16;11(1):18499. doi: 10.1038/s41598-021-97533-8. IF 4.379
  • Lidzba N, García Arteaga V, Schiermeyer A, Havenith H, Muranyi I, Schillberg S, Lehmann J, Ueberham E. Development of Monoclonal Antibodies against Pea Globulins for Multiplex Assays Targeting Legume Proteins. J Agric Food Chem. 2021 Mar 10;69(9):2864-2874. doi: 10.1021/acs.jafc.0c07177. Epub 2021 Feb 25. IF 5.279
  • Riemschneider S, Hoffmann M, Schwertassek U, Weber K, Hauschildt S, Lehmann J. Indol-3-carbinol and quercetin ameliorate chronic DSS-induced colitis in C57BL/6 mice by AhR-mediated anti-inflammatory mechanisms. Int J Environ Res Public Health. 2021 Feb 25;18(5):2262. doi: 10.3390/ijerph18052262. IF 2.849
  • Schaffert A, Krieg L, Weiner J, Schlichting R, Ueberham E, Karkossa I, Bauer M, Landgraf K, Junge KM, Wabitsch M, Lehmann J, Escher BI, Zenclussen AC, Körner A, Blüher M, Heiker JT, von Bergen M, Schubert K. Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation. Environ Int. 156 (2021), 106730. doi: 10.1016/j.envint.2021.106730. IF 9.621

2020

  • Ayobahan SU, Eilebrecht S, Baumann L, Teigeler M, Hollert H, Kalkhof S, Eilebrecht E, Schäfers C. Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Chemosphere. 2020 Feb;240:124970. doi: 10.1016/j.chemosphere.2019.124970. Epub 2019 Sep 25. PMID: 31726584
  • Bedulina D, Drozdova P, Gurkov A, von Bergen M, Stadler PF, Luckenbach T, Timofeyev M, Kalkhof S. Proteomics reveals sex-specific heat shock response of Baikal amphipod Eulimnogammarus cyaneus. Sci Total Environ. 2021 Apr 1;763:143008. doi: 10.1016/j.scitotenv.2020.143008. Epub 2020 Oct 19. PMID: 33187699
  • Friedrich M, Wiedemann K, Reiche K, Puppel S-H, Pfeifer G, Zipfel I, Binder S, Köhl U, Müller GA, Engeland K, Aigner A, Füssel S, Fröhner M, Peitzsch C, Dubrovska A, Rade M, Christ S, Schreiber S, Hackermüller J, Lehmann J, Toma MI, Muders MH, Sommer U, Baretton GB, Wirth M, Horn F. The Role of lncRNAs TAPIR-1 and -2 as Diagnostic Markers and Potential Therapeutic Targets in Prostate Cancer. Cancers (Basel). 2020 Apr 30;12(5):1122. doi: 10.3390/cancers12051122. IF 6.639
  • Hsu MJ, Karkossa I, Schäfer I, Christ M, Kühne H, Schubert K, Rolle-Kampczyk UE, Kalkhof S, Nickel S, Seibel P, von Bergen M, Christ B. Mitochondrial Transfer by Human Mesenchymal Stromal Cells Ameliorates Hepatocyte Lipid Load in a Mouse Model of NASH. Biomedicines. 2020 Sep 14;8(9):350. doi: 10.3390/biomedicines8090350. PMID: 32937969
  • Kalkhof S, Krieg L, Büttner P, Wabitsch M, Küntzel C, Friebe D, Landgraf K, Hanschkow M, Schubert K, Kiess W, Krohn K, Blüher M, von Bergen M, Körner A. In Depth Quantitative Proteomic and Transcriptomic Characterization of Human Adipocyte Differentiation Using the SGBS Cell Line. Proteomics. 2020 May 8;e1900405. doi: 10.1002/pmic.201900405. Online ahead of print. PMID: 32384580
  • Semwal DK, Chauhan A, Semwal RB, Sircar D, Roy P, Lehmann J. Natural molecules having anti-SARS-CoV activity – Can’t they be effective against SARS-CoV-2? Current Science 119 (1) (2020); IF 0.756

 

2019

  • Al-Essa MK, Melzer S, Tárnok A. Two-Color Analysis of Leukocytes Labeled by Modified RBCs and Their Fragments. Cytometry A. 2019 Mar;95(3):339-346. doi: 10.1002/cyto.a.23682. Epub 2018 Dec 21
  • Aswal S, Kumar A, Ruchi Badoni Semwal RB, Chauhan A, Kumar A, Lehmann J, Kumar Semwal D. Drimia indica - A traditional medicine with its comprehensive scientific perspective. Medicina, 55 (2019), 255  doi: 10.3390/medicina55060255. IF 1.429
  • Ayobahan SU, Eilebrecht E, Kotthoff M, Baumann L, Eilebrecht S, Teigeler M, Hollert H, Kalkhof S, Schäfers C. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. Sci Rep. 2019 Apr 29;9(1):6599. doi: 10.1038/s41598-019-43089-7. IF 4.011
  • Ayobahan SU, Eilebrecht S, Baumann L, Teigeler M, Hollert H, Kalkhof S, Eilebrecht E, Schäfers C. Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Chemosphere. 2020 Feb;240:124970. doi: 10.1016/j.chemosphere.2019.124970. Epub 2019 Sep 25. IF 5.35
  • Bengtsson E, Tárnok A. Special Section on Image Cytometry. Cytometry A. 2019 Apr;95(4):363-365. doi: 10.1002/cyto.a.23762
  • Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andrä I, Annunziato F, Anselmo A, Bacher P, Baldari CT, Bari S, Barnaba V, Barros-Martins J, Battistini L, Bauer W, Baumgart S, Baumgarth N, Baumjohann D, Baying B, Bebawy M, Becher B, Beisker W, Benes V, Beyaert R, Blanco A, Boardman DA, Bogdan C, Borger JG, Borsellino G, Boulais PE, Bradford JA, Brenner D, Brinkman RR, Brooks AES, Busch DH, Büscher M, Bushnell TP, Calzetti F, Cameron G, Cammarata I, Cao X, Cardell SL, Casola S, Cassatella MA, Cavani A, Celada A, Chatenoud L, Chattopadhyay PK, Chow S, Christakou E, Čičin-Šain L, Clerici M, Colombo FS, Cook L, Cooke A, Cooper AM, Corbett AJ, Cosma A, Cosmi L, Coulie PG, Cumano A, Cvetkovic L, Dang VD, Dang-Heine C, Davey MS, Davies D, De Biasi S, Del Zotto G, Dela Cruz GV, Delacher M, Della Bella S, Dellabona P, Deniz G, Dessing M, Di Santo JP, Diefenbach A, Dieli F, Dolf A, Dörner T, Dress RJ, Dudziak D, Dustin M, Dutertre CA, Ebner F, Eckle SBG, Edinger M, Eede P, Ehrhardt GRA, Eich M, Engel P, Engelhardt B, Erdei A, Esser C, Everts B, Evrard M, Falk CS, Fehniger TA, Felipo-Benavent M, Ferry H, Feuerer M, Filby A, Filkor K, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frehse B, Frenette PS, Frischbutter S, Fritzsche W, Galbraith DW, Gangaev A, Garbi N, Gaudilliere B, Gazzinelli RT, Geginat J, Gerner W, Gherardin NA, Ghoreschi K, Gibellini L, Ginhoux F, Goda K, Godfrey DI, Goettlinger C, González-Navajas JM, Goodyear CS, Gori A, Grogan JL, Grummitt D, Grützkau A, Haftmann C, Hahn J, Hammad H, Hämmerling G, Hansmann L, Hansson G, Harpur CM, Hartmann S, Hauser A, Hauser AE, Haviland DL, Hedley D, Hernández DC, Herrera G, Herrmann M, Hess C, Höfer T, Hoffmann P, Hogquist K, Holland T, Höllt T, Holmdahl R, Hombrink P, Houston JP, Hoyer BF, Huang B, Huang FP, Huber JE, Huehn J, Hundemer M, Hunter CA, Hwang WYK, Iannone A, Ingelfinger F, Ivison SM, Jäck HM, Jani PK, Jávega B, Jonjic S, Kaiser T, Kalina T, Kamradt T, Kaufmann SHE, Keller B, Ketelaars SLC, Khalilnezhad A, Khan S, Kisielow J, Klenerman P, Knopf J, Koay HF, Kobow K, Kolls JK, Kong WT, Kopf M, Korn T, Kriegsmann K, Kristyanto H, Kroneis T, Krueger A, Kühne J, Kukat C, Kunkel D, Kunze-Schumacher H, Kurosaki T, Kurts C, Kvistborg P, Kwok I, Landry J, Lantz O, Lanuti P, LaRosa F, Lehuen A, LeibundGut-Landmann S, Leipold MD, Leung LYT, Levings MK, Lino AC, Liotta F, Litwin V, Liu Y, Ljunggren HG, Lohoff M, Lombardi G, Lopez L, López-Botet M, Lovett-Racke AE, Lubberts E, Luche H, Ludewig B, Lugli E, Lunemann S, Maecker HT, Maggi L, Maguire O, Mair F, Mair KH, Mantovani A, Manz RA, Marshall AJ, Martínez-Romero A, Martrus G, Marventano I, Maslinski W, Matarese G, Mattioli AV, Maueröder C, Mazzoni A, McCluskey J, McGrath M, McGuire HM, McInnes IB, Mei HE, Melchers F, Melzer S, Mielenz D, Miller SD, Mills KHG, Minderman H, Mjösberg J, Moore J, Moran B, Moretta L, Mosmann TR, Müller S, Multhoff G, Muñoz LE, Münz C, Nakayama T, Nasi M, Neumann K, Ng LG, Niedobitek A, Nourshargh S, Núñez G, O'Connor JE, Ochel A, Oja A, Ordonez D, Orfao A, Orlowski-Oliver E, Ouyang W, Oxenius A, Palankar R, Panse I, Pattanapanyasat K, Paulsen M, Pavlinic D, Penter L, Peterson P, Peth C, Petriz J, Piancone F, Pickl WF, Piconese S, Pinti M, Pockley AG, Podolska MJ, Poon Z, Pracht K, Prinz I, Pucillo CEM, Quataert SA, Quatrini L, Quinn KM, Radbruch H, Radstake TRDJ, Rahmig S, Rahn HP, Rajwa B, Ravichandran G, Raz Y, Rebhahn JA, Recktenwald D, Reimer D, Reis E Sousa C, Remmerswaal EBM, Richter L, Rico LG, Riddell A, Rieger AM, Robinson JP, Romagnani C, Rubartelli A, Ruland J, Saalmüller A, Saeys Y, Saito T, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sandrock I, Santoni A, Sanz RB, Saresella M, Sautes-Fridman C, Sawitzki B, Schadt L, Scheffold A, Scherer HU, Schiemann M, Schildberg FA, Schimisky E, Schlitzer A, Schlosser J, Schmid S, Schmitt S, Schober K, Schraivogel D, Schuh W, Schüler T, Schulte R, Schulz AR, Schulz SR, Scottá C, Scott-Algara D, Sester DP, Shankey TV, Silva-Santos B, Simon AK, Sitnik KM, Sozzani S, Speiser DE, Spidlen J, Stahlberg A, Stall AM, Stanley N, Stark R, Stehle C, Steinmetz T, Stockinger H, Takahama Y, Takeda K, Tan L, Tárnok A, Tiegs G, Toldi G, Tornack J, Traggiai E, Trebak M, Tree TIM, Trotter J, Trowsdale J, Tsoumakidou M, Ulrich H, Urbanczyk S, van de Veen W, van den Broek M, van der Pol E, Van Gassen S, Van Isterdael G, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Borstel A, von Volkmann K, Waisman A, Walker RV, Wallace PK, Wang SA, Wang XM, Ward MD, Ward-Hartstonge KA, Warnatz K, Warnes G, Warth S, Waskow C, Watson JV, Watzl C, Wegener L, Weisenburger T, Wiedemann A, Wienands J, Wilharm A, Wilkinson RJ, Willimsky G, Wing JB, Winkelmann R, Winkler TH, Wirz OF, Wong A, Wurst P, Yang JHM, Yang J, Yazdanbakhsh M, Yu L, Yue A, Zhang H, Zhao Y, Ziegler SM, Zielinski C, Zimmermann J, Zychlinsky A. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). Eur J Immunol. 2019 Oct;49(10):1457-1973. doi: 10.1002/eji.201970107
  • Czechowska K, Lannigan J, Aghaeepour N, Back JB, Begum J, Behbehani G, Bispo C, Bitoun D, Fernández AB, Boova ST, Brinkman RR, Ciccolella CO, Cotleur B, Davies D, Dela Cruz GV, Del Rio-Guerra R, Des Lauriers-Cox AM, Douagi I, Dumrese C, Bonilla Escobar DL, Estevam J, Ewald C, Fossum A, Gaudillière B, Green C, Groves C, Hall C, Haque Y, Hedrick MN, Hogg K, Hsieh EWY, Irish J, Lederer J, Leipold M, Lewis-Tuffin LJ, Litwin V, Lopez P, Nasdala I, Nedbal J, Ohlsson-Wilhelm BM, Price KM, Rahman AH, Rayanki R, Rieger AM, Robinson JP, Shapiro H, Sun YS, Tang VA, Tesfa L, Telford WG, Walker R, Welsh JA, Wheeler P, Tárnok A. Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2019 Conference Workshops. Cytometry A. 2019 Dec;95(12):1236-1274. doi: 10.1002/cyto.a.23941
  • Czechowska K, Lannigan J, Wang L, Arcidiacono J, Ashhurst TM, Barnard RM, Bauer S, Bispo C, Bonilla DL, Brinkman RR, Cabanski M, Chang HD, Chakrabarti L, Chojnowski G, Cotleur B, Degheidy H, Dela Cruz GV, Eck S, Elliott J, Errington R, Filby A, Gagnon D, Gardner R, Green C, Gregory M, Groves CJ, Hall C, Hammes F, Hedrick M, Hoffman R, Icha J, Ivaska J, Jenner DC, Jones D, Kerckhof FM, Kukat C, Lanham D, Leavesley S, Lee M, Lin-Gibson S, Litwin V, Liu Y, Molloy J, Moore JS, Müller S, Nedbal J, Niesner R, Nitta N, Ohlsson-Wilhelm B, Paul NE, Perfetto S, Portat Z, Props R, Radtke S, Rayanki R, Rieger A, Rogers S, Rubbens P, Salomon R, Schiemann M, Sharpe J, Sonder SU, Stewart JJ, Sun Y, Ulrich H, Van Isterdael G, Vitaliti A, van Vreden C, Weber M, Zimmermann J, Vacca G, Wallace P, Tárnok A. Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops. Cytometry A. 2019 Jun;95(6):598-644. doi: 10.1002/cyto.a.23777
  • Czechowska K, Tárnok A. New on the block: The workshop reports. Cytometry A. 2019 Jun;95(6):595-597. doi: 10.1002/cyto.a.23800
  • Del Zotto G, Preijers F, Tárnok A. Phenotype Reports: A new Manuscript Type. Cytometry A. 2019 Jun;95(6):645-646. doi: 10.1002/cyto.a.23796. Epub 2019 May 16
  • Gavasso S, Bringeland GH, Tárnok A. Receptor occupation in the fjords. Cytometry A. 2019 Oct;95(10):1044-1045. doi: 10.1002/cyto.a.23910
  • Haange S-B, Jehmlich N, Hoffmann M, Weber K, Lehmann J, von Bergen M, Schwertassek U. Metaproteomics revealed disease-related changes in bacterial protein abundance and functions in a refined model of dextran sulfate sodium (DSS)-induced colitis. J. Proteome Res. 18 (2019), 1774-1786, Epub 2019 Mar 26. doi: 10.1021/acs.jproteome.8b00974. IF 4.268
  • Hillmann A, Paebst F, Brehm W, Piehler D, Schubert S, Tárnok A, Burk J. A novel direct co-culture assay analyzed by multicolor flow cytometry reveals context- and cell type-specific immunomodulatory effects of equine mesenchymal stromal cells. PLoS One. 2019 Jun 27;14(6):e0218949. doi: 10.1371/journal.pone.0218949. eCollection 2019
  • Kern K, Havenith H, Delaroque N, Rautenberger P, Lehmann J, Fischer M, Spiegel H, Schillberg S, Ehrentreich-Förster E, Aurich S, Treudler R, Szardenings M. The immunome of soy allergy: Comprehensive identification and characterization of epitopes. Clin Exp Allergy. 2019 Feb;49(2):239-251. doi: 10.1111/cea.13285. Epub 2018 Dec 3. IF 5.158
  • Küster E, Kalkhof S, Aulhorn S, von Bergen M, Gündel U. Effects of Five Substances with Different Modes of Action on Cathepsin H, C and L Activities in Zebrafish Embryos. Int J Environ Res Public Health. 2019 Oct 17;16(20):3956. doi: 10.3390/ijerph16203956. IF 2.145
  • Rauwald HW, Liebold T, Grötzinger K, Lehmann J, Kuchta K. Labdanum and Labdanes of Cistus creticus and C. ladanifer. Anti-Borrelia Activity and its Phytochemical Profiling. Phytomedicine. 2019 Jul;60:152977. doi: 10.1016/j.phymed.2019.152977. Epub 2019 May 31. IF 3.61
  • Szendy M, Kalkhof S, Bittrich S, Kaiser F, Leberecht C, Labudde D, Noll M. Structural change in GadD2 of Listeria monocytogenes field isolates supports nisin resistance. Int J Food Microbiol. 2019 Sep 16;305:108240. doi: 10.1016/j.ijfoodmicro.2019.108240. Epub 2019 Jun 4. IF 4.187
  • Tárnok A. Cancer and Cytometry. Cytometry A. 2019 Mar;95(3):257-258. doi: 10.1002/cyto.a.23740
  • Tárnok A. Computational Cytometry. Cytometry A. 2019 Jul;95(7):706-707. doi: 10.1002/cyto.a.23856
  • Tárnok A. End of Year Note 2019. Cytometry A. 2019 Dec;95(12):1221-1222. doi: 10.1002/cyto.a.23950
  • Tárnok A. New Year Note 2019: Welcome to the Year of the Pig. Cytometry A. 2019 Jan;95(1):9. doi: 10.1002/cyto.a.23714
  • Tárnok A. Nobel prize for medicine 2019 and the impact of cytometry. Cytometry A. 2019 Nov;95(11):1127-1128. doi: 10.1002/cyto.a.23923
  • Tárnok A. SRL Communi(ty)cate. Cytometry A. 2019 Feb 6. doi: 10.1002/cyto.a.23727. Online ahead of print.
  • Tárnok A. Supervised Cytometry. Cytometry A. 2019 Sep;95(9):941-942. doi: 10.1002/cyto.a.23894
  • Ueberham E, Spiegel H, Havenith H, Rautenberger P, Lidzba N, Schillberg S, Lehmann J. Simplified Tracking of a Soy Allergen in Processed Food Using a Monoclonal Antibody-Based Sandwich ELISA Targeting the Soybean 2S Albumin Gly m 8. J Agric Food Chem. 2019 Aug 7;67(31):8660-8667. doi: 10.1021/acs.jafc.9b02717. Epub 2019 Jul 29. IF 3.571
  • Valainis D, Dondl P, Foehr P, Burgkart R, Kalkhof S, Duda GN, van Griensven M, Poh PSP. Integrated additive design and manufacturing approach for the bioengineering of bone scaffolds for favorable mechanical and biological properties. Biomed Mater. 2019 Sep 9;14(6):065002. doi: 10.1088/1748-605X/ab38c6. IF 3.30
  • Wichmann G, Gaede C, Melzer S, Bocsi J, Henger S, Engel C, Wirkner K, Wenning JR, Wald T, Freitag J, Willner M, Kolb M, Wiegand S, Löffler M, Dietz A, Tárnok A. Discrimination of Head and Neck Squamous Cell Carcinoma Patients and Healthy Adults by 10-Color Flow Cytometry: Development of a Score Based on Leukocyte Subsets. Cancers (Basel). 2019 Jun 12;11(6):814. doi: 10.3390/cancers11060814

2018

  • Fueldner C, Kohlschmidt J, Riemschneider S, Schulze F, Zoldan K, Esser C, Hauschildt S, Lehmann J. Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner. Toxicology. 2018 Nov 1;409:80-90. doi: 10.1016/j.tox.2018.07.011. Epub 2018 Jul 24. IF 3.265
  • Hoffmann M, Schwertassek U, Seydel A, Weber K, Falk W, Hauschildt S, Lehmann J. A refined and translationally relevant model of chronic DSS colitis in BALB/c mice. Lab Anim. 2018 Jun;52(3):240-252. doi: 10.1177/0023677217742681. Epub 2017 Dec 1. IF 1.532
  • Riemschneider S, Kohlschmidt J, Fueldner C, Esser C, Hauschildt S, Lehmann J. Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macrophages. Toxicol Lett. 2018 Oct 15;296:106-113. doi: 10.1016/j.toxlet.2018.07.050. Epub 2018 Aug 9. IF 3.166

2017

  • Havenith H, Kern K, Rautenberger P, Spiegel H, Szardenings M, Ueberham E, Lehmann J, Buntru M, Vogel S, Treudler R, Fischer R, Schillberg S. Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants. Biotechnol J. 2017 Feb;12(2). doi: 10.1002/biot.201600441. PMID: 27906504; IF 3.649
  • Hoffmann M, Schwertassek U, Seydel A, Weber K, Hauschildt S, Lehmann J. Therapeutic efficacy of a combined sage and bitter apple phytopharmaceutical in chronic DSS-induced colitis. Sci Rep. 2017 Oct 27;7(1):14214. doi: 10.1038/s41598-017-13985-x. IF 4.259
  • Meinlschmidt P, Brode V, Sevenich R, Ueberham E, Schweiggert-Weisz U, Lehmann J, Rauh D, Knorr D, Eisner P. High pressure processing assisted enzymatic hydrolysis - an innovative approach for the reduction of soy immunoreactivity. Innovative Food Science and Emerging Technologies, 40 (2017), 58-67. doi: 10.1016/j.ifset.2016.06.022. IF 2.573
  • Theuß T, Ueberham E, Lehmann J, Lindner T, Springer S. Immunogenic Potential of a Salmonella Typhimurium Live Vaccine for Pigs against monophasic Salmonella Typhimurium DT 193. BMC Veterinary Research 13 (2017), 343; IF 1.75. https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-017-1271-5
  • Zoldan K, Schneider J, Moellmer T, Fueldner C, Knauer J, Fuerll M, Starke A, Specht M, Reiche K, Hackermueller J, Kalkhof S, von Bergen M, Bergfeld U, Fischer R, Pache S, Lehmann J. Discovery and Validation of Immunological Biomarkers in Milk for Health Monitoring of Dairy Cows - Results from a Multiomics Approach. J Adv Dairy Res 5 (2017): 182. ISSN: 2329-888X; doi: 10.4172/2329-888X.1000182. IF 1.684

2016

  • Hilger N, Glaser J, Müller C, Halbich C, Müller A, Schwertassek U, Lehmann J, Ruschpler P, Lange F, Boldt A, Stahl L, Sack U, Oelkrug C, Emmrich F, Fricke S. Attenuation of graft-versus-host-disease in NOD scid IL-2Rγ(-/-) (NSG) mice by ex vivo modulation of human CD4(+) T cells. Cytometry A. 2016 Sep;89(9):803-15. doi: 10.1002/cyto.a.22930. Epub 2016 Aug 25. PMID: 27560708; IF 3.222
  • Meinlschmidt P, Ueberham E, Lehmann J, Reineke K, Schlüter O, Eisner P, Schweiggert-Weisz U, Knorr D. Application of nonthermal technologies for the mitigation of soy immunoreactivity – pulsed ultraviolet light, -irradiation, and nonthermal atmospheric plasma. Innovative Food Science and Emerging Technologies, 38 (2016), 374-383; ISSN: 1466-8564; doi: 10.1016/j.ifset.2016.06.007. IF 2.573
  • Meinlschmidt P, Ueberham E, Lehmann J, Schweiggert-Weisz U, Eisner P. Immunoreactivity, sensory and physicochemical properties of fermented soy protein isolate. Food Chem. 2016 Aug 15;205:229-38. doi: 10.1016/j.foodchem.2016.03.016. Epub 2016 Mar 8. PMID: 27006235; IF 4.529

2015

  • Lehmann J, Schulz RM, Sanzenbacher R. Strategic considerations on the design and choice of animal models for non-clinical investigations of cell-based medicinal products. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2015 Nov;58(11-12):1215-24. doi: 10.1007/s00103-015-2239-x. German. PMID: 26431722; IF 1.422
  • Riemschneider S, Herzberg M, Lehmann J. Subtoxic Doses of Cadmium Modulate Inflammatory Properties of Murine RAW 264.7 Macrophages. Biomed Res Int. 2015;2015:295303. doi: 10.1155/2015/295303. Epub 2015 Aug 3. PMID: 26339604; IF 1.579
  • Zscharnack M, Krause C, Aust G, Thümmler C, Peinemann F, Keller T, Smink JJ, Holland H, Somerson JS, Knauer J, Schulz RM, Lehmann J. Preclinical good laboratory practice-compliant safety study to evaluate biodistribution and tumorigenicity of a cartilage advanced therapy medicinal product (ATMP). J Transl Med. 2015 May 20;13:160. doi: 10.1186/s12967-015-0517-x. PMID: 25990108; IF 3.93

2014

  • Fricke S, Pfefferkorn C, Wolf D, Riemschneider S, Kohlschmidt J, Hilger N, Fueldner C, Knauer J, Sack U, Emmrich F, Lehmann J. Characterization of the murine myeloid precursor cell line MuMac-E8. PLoS One. 2014 Dec 29;9(12):e113743. doi: 10.1371/journal.pone.0113743. eCollection 2014. Erratum in: PLoS One. 2015;10(4):e0119657. PMID: 25546418; IF 3.234
  • Lehmann J, Härtig W, Seidel A, Füldner C, Hobohm C, Grosche J, Krueger M, Michalski D. Inflammatory cell recruitment after experimental thromboembolic stroke in rats. Neuroscience. 2014 Oct 24;279:139-54. doi: 10.1016/j.neuroscience.2014.08.023. Epub 2014 Aug 26. PMID: 25168731; IF 3.357
  • Wege AK, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, Lehmann J. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. MAbs. Jul-Aug 2014;6(4):968-77. doi: 10.4161/mabs.29111. Epub 2014 May 8. PMID: 24870377; IF 4.558
  • Zoldan K, Moellmer T, Schneider J, Fueldner C, Knauer J, Lehmann J. Increase of CD25 expression on bovine neutrophils correlates with disease severity in post-partum and early lactating dairy cows. Dev Comp Immunol. 2014 Dec;47(2):254-63. doi: 10.1016/j.dci.2014.08.002. Epub 2014 Aug 11. PMID: 25106916; IF 2.815

2012

  • Fueldner C, Mittag A, Knauer J, Biskop M, Hepp P, Scholz R, Wagner U, Sack U, Emmrich F, Tárnok A, Lehmann J. Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry. Arthritis Res Ther. 2012 Jan 17;14(1):R8. doi: 10.1186/ar3682. PMID: 22251373; IF 4.302
  • Pohler P, Lehmann J, Veneruso V, Tomm J, von Bergen M, Lambrecht B, Kohn B, Weingart C, Müller TH, Seltsam A. Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model. Transfusion. 2012 Nov;52(11):2414-26. doi: 10.1111/j.1537-2995.2012.03583.x. Epub 2012 Mar 8. PMID: 22404822; IF 3.526

2011

  • Knauer J, Krupka I, Fueldner C, Lehmann J, Straubinger RK. Evaluation of the preventive capacities of a topically applied azithromycin formulation against Lyme borreliosis in a murine model. J Antimicrob Chemother. 2011 Dec;66(12):2814-22. doi: 10.1093/jac/dkr371. Epub 2011 Sep 15. PMID:21921078; IF 3.526
  • Lehmann I, Sack U, Lehmann J. Metal ions affecting the immune system. Met Ions Life Sci. 2011;8:157-85. PMID: 21473381; IF 1.11
  • Roesler U, Szabo I, Matthies C, Albrecht K, Leffler M, Scherer K, Nöckler K, Lehmann J, Methner U, Hensel A, Truyen U. Comparing validation of four ELISA-systems for detection of Salmonella derby- and Salmonella infantis-infected pigs. Berl Munch Tierarztl Wochenschr. Jul-Aug 2011;124(7-8):265-71. PMID: 21848033; IF 0.82
  • Schubert K, Polte T, Bönisch U, Schader S, Holtappels R, Hildebrandt G, Lehmann J, Simon JC, Anderegg U, Saalbach A. Thy-1 (CD90) regulates the extravasation of leukocytes during inflammation. Eur J Immunol. 2011 Mar;41(3):645-56. doi: 10.1002/eji.201041117. Epub 2011 Jan 25. PMID: 21264853; IF 5.068

2010

  • Fricke S, Fricke C, Oelkrug C, Hilger N, Schönfelder U, Kamprad M, Lehmann J, Boltze J, Emmrich F, Sack U. Characterization of murine non-adherent bone marrow cells leading to recovery of endogenous hematopoiesis. Cell Mol Life Sci. 2010 Dec;67(23):4095-106. doi: 10.1007/s00018-010-0427-2. Epub 2010 Jun 18. PMID: 20556631; IF 7.047
  • Zoldan K, Arnold A, Stolzing A, Lehmann J. Automated harvest of induced pluripotent stem cell colonies and colony fractions using the cell separation robot CellCelector™. App. Note, Nature Methods, Online publication. http://www.nature.com/app_notes/nmeth/2010/101008/pdf/an7723.pdf; IF 20.717
  • Zoldan K, Arnold A, Stolzing A, Lehmann J. Visualizing of migration, interaction, proliferation or differentiation of cells in time lapse exposures using the cell separation robot CellCelector™. App. Note, Nature Methods, Online publication; IF 20.717
  • Zoldan K, Füldner C, Schubert A, Lehmann J. Automated isolation of semi-adherent macrophage-like cells from a fibroblast contaminated culture using the cell separation robot CellCelector™. App. Note, Nature Methods, Online publication; IF 20.717
  • Zoldan K, Knauer J, Lehmann J. Automated clonal selection of hybridoma colonies from methylcellulose-based, semi-solid medium using the CellCelector™.  App. Note, Nature Methods, Online publication; IF 20.717

2008

  • Pfefferkorn, C., Scholz, U., Veneruso, V., Nikolaus, T., Madin, K., Eichenlaub, U., Schubert, A., and Lehmann, J. Influence of Serum Deprivation on Adherence and Proliferation of Murine Mesenchymal Progenitor Cells Analysed with Roche´s xCELLigence System. Biochemica.2008 4:14-16
  • Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, Lehmann J, Sack U. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008 Apr;73(4):351-60. doi: 10.1002/cyto.a.20532. PMID: 18307273; IF 3.259
  • Trepnau D, Ulrich E, Uhlig R, Lindner T, Selbitz HJ, Rösler U, Gabert J, Bergfeld U, Fehlhaber K, Brabetz W, Lehmann J. Antibody response after immunization with a Salmonella Typhimurium live vaccine in dependence on the way of application. Berl Munch Tierarztl Wochenschr. Sep-Oct 2008;121(9-10):334-40. German. PMID: 18822604; IF 0.812

2007

  • Brumme S, Arnold T, Sigmarsson H, Lehmann J, Scholz HC, Hardt WD, Hensel A, Truyen U, Roesler U. Impact of Salmonella Typhimurium DT104 virulence factors invC and sseD on the onset, clinical course, colonization patterns and immune response of porcine salmonellosis. Vet Microbiol. 2007 Oct 6;124(3-4):274-85. doi: 10.1016/j.vetmic.2007.04.032. Epub 2007 Apr 27. PMID: 17524577; IF 1.169
  • Hemdan NY, Emmrich F, Faber S, Lehmann J, Sack U. Alterations of TH1/TH2 reactivity by heavy metals: possible consequences include induction of autoimmune diseases. Ann N Y Acad Sci. 2007 Aug;1109:129-37. doi: 10.1196/annals.1398.015. PMID: 17785298; IF 0.45
  • Hemdan NY, Lehmann I, Wichmann G, Lehmann J, Emmrich F, Sack U. Immunomodulation by mercuric chloride in vitro: application of different cell activation pathways. Clin Exp Immunol. 2007 May;148(2):325-37. doi: 10.1111/j.1365-2249.2007.03338.x. Epub 2007 Feb 14. PMID: 17302730; IF 2.599

2006

  • Ehlers J, Alt M, Trepnau D, Lehmann J. Use of new immunoglobulin isotype-specific ELISA-systems to detect Salmonella infections in pigs. Berl Munch Tierarztl Wochenschr. Nov-Dec 2006;119(11-12):461-6. German. PMID: 17172133; IF 0.611
  • Härtig W, Lehmann J, Stieler J, Singer D, Grosche J, Arendt T, Hoffmann R. Simultaneous detection of tau phospho-epitopes with haptenylated antibodies. Neuroreport. 2006 Jun 26;17(9):869-74. doi: 10.1097/01.wnr.0000215778.76602.da. PMID: 16738478; IF 2.137
  • Hemdan NY, Emmrich F, Sack U, Wichmann G, Lehmann J, Adham K, Lehmann I. The in vitro immune modulation by cadmium depends on the way of cell activation. Toxicology. 2006 May 1;222(1-2):37-45. doi: 10.1016/j.tox.2006.01.026. Epub 2006 Feb 28. PMID: 16510232; IF 2.685
  • Lehmann J, Springer S, Werner CE, Lindner T, Bellmann S, Straubinger RK, Selbitz HJ, Alber G. Immunity induced with a Salmonella enterica serovar Enteritidis live vaccine is regulated by Th1-cell-dependent cellular and humoral effector mechanisms in susceptible BALB/c mice. Vaccine. 2006 May 29;24(22):4779-93. doi: 10.1016/j.vaccine.2006.03.024. Epub 2006 Mar 29. PMID: 16647169; IF 3.159
  • Singer D, Lehmann J, Hanisch K, Härtig W, Hoffmann R. Neighbored phosphorylation sites as PHF-tau specific markers in Alzheimer's disease. Biochem Biophys Res Commun. 2006 Aug 4;346(3):819-28. doi: 10.1016/j.bbrc.2006.05.201. Epub 2006 Jun 9. PMID: 16781671; IF 0.611