© Fraunhofer IZI

The goal of the Bioinformatics Unit is early diagnosis and improved risk stratification for personalized medicine in order to enable an individualized choice of therapy for patients. This is where we come in with computer-assisted methods combined with omic-wide and multi-modal analytical procedures.

A wide range of methods enables us to implement a customized solution for your precision medicine challenge:

  • We accompany you in the development of algorithms and classification models for in vitro diagnostics.
  • We support you in gaining detailed insights into mechanisms of action and resistance for novel drugs, such as gene and cell therapies.
  • We are your partner for an accompanying evaluation of treatment results for clinical trials, using omic-wide and multi-modal measurements.
  • If required, we support you in the implementation of the resulting biomarker signature as a software prototype for medical devices (for example, as an in vitro diagnostic).
  • We implement our development processes within the framework of a certified quality management system (ISO 9001:2015).
  • The software lifecycle is planned and managed in accordance with IEC 62304 and carried out in compliance with risk management in accordance with ISO 14971.

In cooperation with the Next-Generation Diagnostics Unit and the Advanced Analytics Technology Platform, we implement multi-modal measurements for precision medicine.


  • Machine Learning
  • Statistical Learning
  • AI
  • Bioinformatics
  • Multi-modal analysis
  • Integrative Bioinformatics
  • Computational Biology
  • Functional Genomics
Darstellung der verschiedenen Ebenen der molekularen Charakterisierung von Gewebeproben (v.l.n.r): Zusammensetzung des ursprünglichen Gewebes (verschiedene Zellpopulationen sind in verschiedenen Farben dargestellt), Sequenzierung eines Zellgemisches (bulk transcriptomics), Sequenzierung einzelner Zellen (single-cell sequencing) und räumlich aufgelöste Sequenzierung (spatial transcriptomics).
© Fraunhofer IZI
Illustration of the different levels of molecular characterization of tissue samples (from left to right): Composition of the original tissue (different cell populations are shown in different colors), sequencing of a mixture of cells (bulk transcriptomics), sequencing of single cells (single-cell sequencing) and spatially resolved sequencing (spatial transcriptomics).