Department of Medical Bioinformatics

The Department of Medical Bioinformatics studies and develops computer-based and data-supported technologies for the next generation of precision medicine.

To this end, it combines bio-informatics methods with multimodal individual-cell analysis. This permits the characterization of a large number of molecular and cellular markers in individual cells as well as their biomechanical properties. The department develops digital patient twins, biomarkers and biosensors for personalized medicine and formulates new therapeutic target molecules with the help of machine learning and computer-supported biomedicine.

Selected processes used by the department are implemented in line with a certified quality management system (ISO9001:2015). Software components are implemented according to IEC 62304 and ISO 14971 to ensure that the computer-based methods developed can be used in the healthcare sector.

The department also supports preclinical development and assessment of novel therapies by providing detailed insights into their modes of action and assists customers and partners in planning and executing clinical studies through tailor-made bioinformatics workflows, multi-modal individual-cell analyses, and biomechanical cell characteristics.

Units

 

Bioinformatics

The Bioinformatics Unit develops and establishes computer-aided methods for the identification and verification of new biomarkers for personalized diagnosis and prognosis of diseases as well as for the detection of novel therapeutic targets.

 

Next-Generation Diagnostics

The Next-Generation Diagnostics Unit identifies and characterizes disease-associated nucleic acids for their application as diagnostic markers and therapeutic targets, and develops experimental methods for this purpose. 

 

DNA Nanodevices

The work undertaken in this unit focuses on developing diagnostic and therapeutic applications of nanomaterials constructed by methods such as DNA self-assembly and molecular programming.

Competencies of the department

Find out about our competencies here.