Department of Medical Bioinformatics

The Department of Medical Bioinformatics investigates and develops computer-based and data-driven technologies for the next generation of precision medicine. This involves combining bioinformatics methods with multimodal single-cell analytics. This enables the characterization of a variety of molecular and cellular markers in individual cells, as well as their biomechanical properties. Through the use of machine learning and computational biomedicine, digital patient twins, biomarkers, and biosensors for personalized medicine are developed, and new therapeutic target molecules are described. Selected processes within the department are implemented in a certified quality management system (ISO 9001:2015). Software components are developed according to IEC 62304 and ISO 14971 to ensure the application of developed computer-based methods in healthcare. The department supports the preclinical development and evaluation of new therapies by providing detailed insights into their mechanisms of action and assists clients and partners in planning and conducting clinical studies through tailored bioinformatics workflows as well as multimodal single-cell analytics and biomechanical cell characteristics.