The unit carries out research into infectious diseases relevant to cardiac surgery using state-of-the-art OMICS technology platforms. Infective endocarditis and the development of molecular biological diagnostic procedures are of particular scientific interest here, as is the translation of such procedures into routine clinical practice. In addition, prostheses, bone and wound infections are analyzed molecularly and biologically with regard to their pathogen spectrum. On this basis, existing and alternative treatment methods are evaluated and new interventional procedures taken to clinical maturity.
The unit will concentrate on the connection between infectious diseases and molecular regulatory mechanisms associated with haemostasis. In the interdisciplinary field of intervention strategies relating to cardiac surgery, the diagnosis and therapeutic intervention of the coagulation system play a vital role. The unit primarily develops diagnostic procedures to determine the effect of factor X inhibitors and / or coagulation diagnostics during the final stages of plasma coagulation.