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As technical methods continue to be advanced, new imaging procedures and evaluation methods used to depict structures and processes are always available for biological investigations.
The Department of Cell Therapy prepares new gene and cell therapy procedures for clinical application. This involves the validation of experimental approaches with an eye to safety, feasibility and efficiency. Numerous model systems that facilitate the preclinical testing of novel concepts under the strictest quality criteria have been and continue to be established by the department. These systems lend the obtained results a high level of predictive power with regard to their future clinical application. Cell therapeutic methods are used, for instance, in the case of ischemic diseases such as stroke and myocardial infarction while attention is also given to processes that could prevent cell degeneration and aging. The ”sleeping” potential of stem cells is also investigated. Last but not least, the department focuses on cell therapy methods in the field of immuno-oncology, where genetically modified immune cells (cytotoxic T-cells) or natural killer cells (NK cells) are developed to treat tumors.