Department of Extracorporeal Immunomodulation

The Fraunhofer department in Rostock mainly works in the areas of blood purification and detoxification therapies.

Medical device development

  • In vitro models for extracorporeal methods (organ support outside the patient's body)
  • Process development (e.g. new methods for liver replacement therapy)
  • Creating prototypes
  • Constructing bioreactors
  • Analyzing functional models (e.g. testing dialysis membranes or adsorber cartridges)

Diagnostic and therapeutic cell cultures

  • In-vitro toxicity according to ISO 10933-5 for medical products
  • Analysis of hepatotoxicity (drugs and medical products)
  • Biosensor technology: Early detection of liver failure
  • Producing immune cell concentrates (accumulating granulocytes from whole blood)

Chemical analysis (GCMS, LCMS)

  • Endotoxins
  • Lipophilic protein ligands (especially albumin-bound toxins)

Clinical trials

  • Preclinical and clinical trials with large patient populations
  • Study design, conduct and evaluation
  • Regulatory aspects

Clinical expertise

  • Nephrology
  • Dialysis
  • Intensive medicine
  • Sepsis