Fraunhofer Institute for Cell Therapy and Immunology IZIMedicinal chemistry / Small Molecules
- Ligand- and structure-based design of enzyme inhibitors and receptor ligands
- Synthesis and characterisation of low-molecular drug molecules
- Fully equipped laboratories for drug synthesis
- Conventional synthesis, microwave synthesis, flow chemistry
- Analytical characterisation using HPLC, MS, NMR (external), HRMS (external)
- Peptide synthesis
- Exploration of structure-activity relationships
- Various cheminformatics software packages
- Homology modeling
- Pharmacophore modeling
- Docking & virtual screening
- Generation of virtual compound libraries
- Documentation and compound management with an electronic laboratory journal and compound inventory system