In the disCoVer 21 project, a diagnostic test based on PCR-free detection is to be developed. This would eliminate lengthy analysis steps (transcription of RNA into DNA and subsequent PCR), which sometimes lead to long waiting times for a smear result.
Due to a shortened analysis time, infected persons can be identified, isolated and treated more quickly if necessary. At the same time, chains of infection can be better traced in order to further reduce the spread of the virus.
To simplify sample analysis and increase throughput in laboratories, disCoVer 21 targets highly sensitive lateral flow test strips on which the target substances are directly and specifically detected. From the Fraunhofer Institute for Cell Therapy and Immunology IZI the units MicroDiagnostics and Preclinical Validation are working on the project.