Department of Extracorporeal Therapy Systems

The Fraunhofer department in Rostock mainly works in the areas of blood purification and detoxification therapies.

Medical device development

• In vitro models for extracorporeal methods (organ support outside the patient's body)
• Process development (e.g. new methods for liver replacement therapy)
• Creating prototypes
• Constructing bioreactors
• Analyzing functional models (e.g. testing dialysis membranes or adsorber cartridges)

Diagnostic and therapeutic cell cultures

• In-vitro toxicity according to ISO 10933-5 for medical products
• Analysis of hepatotoxicity (drugs and medical products)
• Biosensor technology: Early detection of liver failure
• Producing immune cell concentrates (accumulating granulocytes from whole blood)

Chemical analysis (GCMS, LCMS)

• Endotoxins
• Lipophilic protein ligands (especially albumin-bound toxins)

Clinical trials

• Preclinical and clinical trials with large patient populations
• Study design, conduct and evaluation
• Regulatory aspects

Clinical expertise

• Nephrology
• Dialysis
• Intensive medicine
• Sepsis