The proposed project concerns the creation of a competent working group to focus on the development of innovative, smart, bioceramic implants for clinical use in the fields of orthopedics and dentistry. The long-term goal is to introduce immunologically effective biomolecules, pharmaceuticals or semiochemicals to new implants as additives so as to control or regulate the immune system's foreign body granuloma. The materials expertise and the manufacturing technologies for bioceramic materials and surfaces available at the Fraunhofer Institute for Ceramic Technologies and Systems (IKTS) offer a good framework in which to positively control the biological organism's "immune response", this being the response at the interface between implant and tissue, upon introducing foreign matter to the body. This may avoid an initial inflammatory response in the biological organism and support the integrity of the implant in the patient's own peri-implant tissue. This, in turn, is a decisive step in guaranteeing long-lasting stability and reducing the number of revision operations on account of implant loosening and instability in the long run.