In vitro pharmacology

Publications

  • Engel K, Wieland L, Krüger A, Volkmer I, Cynis H, Emmer A, Staege MS. Identification of differentially expressed human endogenous retrovirus families in human leukemia and lymphoma cell lines and stem cells. Front Oncol. 2021 Apr 29;11:637981. doi: 10.3389/fonc.2021.637981. eCollection 2021.
  • Buniatian GH, Weiskirchen R, Weiss TS, Schwinghammer U, Fritz M, Seferyan T, Proksch B, Glaser M, Lourhmati A, Buadze M, Borkham-Kamphorst E, Gaunitz F, Gleiter CH, Lang T, Schaeffeler E, Tremmel R, Cynis H, Frey WH II, Gebhardt R, Friedmann SL, Mikulits W, Schwab M, Danielyan L. Antifibrotic effects of amyloid-beta and its loss in cirrhotic liver. Cells. 2020 Feb 17;9(2):452. doi: 10.3390/cells9020452
  • Lienau C, Gräwert T, Alves Avelar LA, Illarionov B, Held J, Knaab TC, Lungerich B, van Geelen L, Meier D, Geissler S, Cynis H, Riederer U, Buchholz M, Kalscheuer R, Bacher A, Mordmüller B, Fischer M, Kurz T. Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity. Eur J Med Chem. 2019 Nov 1;181:111555. doi: 10.1016/j.ejmech.2019.07.058. Epub 2019 Jul 22.
  • Cynis H, Scheel E, Saido T, Schilling S, Demuth HU. Amyloidogenic processing of amyloid precursor protein: evidence of a pivotal role of Glutaminyl Cyclase in generation of pyroglutamate-modified amyloid-beta. Biochemistry. 2008 Jul 15;47(28):7405-13. doi: 10.1021/bi800250p. Epub 2008 Jun 21.
  • Cynis H, Rahfeld JU, Stephan A, Kehlen A, Koch B, Wermann M, Demuth HU, Schilling S. Isolation of an isoenzyme of human Glutaminyl Cyclase: Retention in the Golgi complex suggests involvement in the protein maturation machinery. J Mol Biol. 2008 Jun 20;379(5):966-80. doi: 10.1016/j.jmb.2008.03.078. Epub 2008 Apr 15.