X-ray structural analysis

Selected publications

  • Linnert M, Fritz C, Jäger C, Schlenzig D, Ramsbeck D, Kleinschmidt M, Wermann M, Demuth H-U, Parthier C, Schilling S. Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor. Int J Mol Sci. 2021 May 26;22(11):5651. doi: 10.3390/ijms22115651
  • Taudte N, Linnert M, Rahfeld J-U, Piechotta A, Ramsbeck D, Buchholz M, Kolenko P, Parthier C, Houston JA, Veillard F, Eick S, Potempa J, Schilling S, Demuth H-U, Stubbs MT. Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis. J Biol Chem. 2021 Jan 5;jbc.RA120.016836. doi: 10.1016/j.jbc.2021.100263
  • Piechotta A, Parthier C, Kleinschmidt M, Gnoth K, Pillot T, Lues I, Demuth H-U, Schilling S, Rahfeld J-U, Stubbs MT. Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy. J Biol Chem. 2017 Jul 28;292(30):12713-12724. doi: 10.1074/jbc.M117.777839
  • Zhu J, Bailly A, Zwiewka M, Sovero V, Di Donato M, Ge P, Oehri J, Aryal B, Hao P, Linnert M, Burgardt NI, Lücke C, Weiwad M, Michel M, Weiergräber OH, Pollmann S, Azzarello E, Mancuso S, Ferro N, Fukao Y, Hoffmann C, Wedlich-Söldner R, Friml J, Thomas C, Geisler M. TWISTED DWARF1 Mediates the Action of Auxin Transport Inhibitors on Actin Cytoskeleton Dynamics. Plant Cell. 2016 Apr;28(4):930-48. doi: 10.1105/tpc.15.00726
  • Linnert M, Lin Y-J, Manns A, Haupt K, Paschke A-K, Fischer G, Weiwad M, Lücke C. The FKBP-type domain of the human aryl hydrocarbon receptor-interacting protein reveals an unusual Hsp90 interaction. Biochemistry. 2013 Mar 26;52(12):2097-107. doi: 10.1021/bi301649m
  • Linnert M, Haupt K, Lin Y-J, Kissing S, Paschke A-K, Fischer G, Weiwad M, Lücke C. NMR assignments of the FKBP-type PPIase domain of the human aryl-hydrocarbon receptor-interacting protein (AIP). Biomol NMR Assign. 2012 Oct;6(2):209-12. doi: 10.1007/s12104-012-9359-0