Vesicle-based Immunomodulation

Publications

  • Jaimes Y, Naaldijk Y, Wenk K, Leovsky C, Emmrich F. Mesenchymal Stem Cell-Derived Microvesicles Modulate Lipopolysaccharides-Induced Inflammatory Responses to Microglia Cells. Stem Cells. 2017 Mar;35(3):812-823. DOI: dx.doi.org/10.1002/stem.2541. Epub 2017 Feb 22.
  • Kieback E, Hilgenberg E, Stervbo U, Lampropoulou V, Shen P, Bunse M, Jaimes Y, Boudinot P, Radbruch A, Klemm U, Kühl AA, Liblau R, Hoevelmeyer N, Anderton SM, Uckert W, Fillatreau S. Thymus-Derived Regulatory T Cells Are Positively Selected on Natural Self-Antigen through Cognate Interactions of High Functional Avidity. Immunity. 2016 May 17;44(5):1114-26. DOI: dx.doi.org/10.1016/j.immuni.2016.04.018.
  • Gras C, Eiz-Vesper B, Jaimes Y, Immenschuh S, Jacobs R, Witte T, Blasczyk R, Figueiredo C. Secreted semaphorin 5A activates immune effector cells and is a biomarker for rheumatoid arthritis. Arthritis Rheumatol. 2014 Jun;66(6):1461-71. DOI: dx.doi.org/10.1002/art.38425.
  • Shen P, Roch T, Lampropoulou V, O'Connor RA, Stervbo U, Hilgenberg E, Ries S, Dang VD, Jaimes Y, Daridon C, Li R, Jouneau L, Boudinot P, Wilantri S, Sakwa I, Miyazaki Y, Leech MD, McPherson RC, Wirtz S, Neurath M, Hoehlig K, Meinl E, Grützkau A, Grün JR, Horn K, Kühl AA, Dörner T, Bar-Or A, Kaufmann SH, Anderton SM, Fillatreau S. IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature. 2014 Mar 20;507(7492):366-370. DOI: dx.doi.org/10.1038/nature12979. Epub 2014 Feb 23.
  • Saragih H, Zilian E, Jaimes Y, Paine A, Figueiredo C, Eiz-Vesper B, Blasczyk R, Larmann J, Theilmeier G, Burg-Roderfeld M, Andrei-Selmer LC, Becker JU, Santoso S, Immenschuh S. PECAM-1-dependent heme oxygenase-1 regulation via an Nrf2-mediated pathway in endothelial cells. Thromb Haemost. 2014 Jun;111(6):1077-88. DOI: dx.doi.org/10.1160/TH13-11-0923. Epub 2014 Feb 6..
  • Jaimes Y, Gras C, Goudeva L, Buchholz S, Eiz-Vesper B, Immenschuh S, Seltsam A, Blasczyk R, Figueiredo C. Platelet differentiation from CD34+ progenitor cells is impaired by semaphorin 7A. J Thromb Haemost. 2012 Jun;10(6):1100-8. DOI: dx.doi.org/10.1111/j.1538-7836.2012.04708.x.
  • Jaimes Y, Seltsam A, Eiz-Vesper B, Blasczyk R, Figueiredo C. Regulation of HLA class II expression prevents allogeneic T-cell responses. Tissue Antigens. 2011 Jan;77(1):36-44. DOI: dx.doi.org/10.1111/j.1399-0039.2010.01576.x.
  • Schlahsa L, Jaimes Y, Blasczyk R, Figueiredo C. G-CSF: a strong inhibitor of NK cell function. Transfusion. 2011 Feb;51(2):293-305. DOI: dx.doi.org/10.1111/j.1537-2995.2010.02820.x. Epub 2010 Aug 16.
  • Jaimes Y, Figueiredo C, Blasczyk R. Silencing the expression of Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) prevents allogeneic T cell cytotoxicity. Transfusion. 2010 Sep;50(9):1988-2000. DOI: dx.doi.org/10.1111/j.1537-2995.2010.02677.x.
  • Figueiredo C, Jaimes Y, Horn PA, Eiz-Vesper B. The new HLA-Cw*0524 allele increase the variability of position 49 in HLA-C. Tissue Antigens. 2009 Sep;74(3):258-9. DOI: dx.doi.org/10.1111/j.1399-0039.2009.01310.x. Epub 2009 Jul 13.